Cardiovascular disease (CVD) refers to any conditions caused by the underlying damage of blood vessels and the heart.
In other words, depending on the location of the blockage or disruption, CVD can be coronary artery diseases (CAD) such as angina, myocardial infarction (commonly known as a heart attack) or stroke.
According to the statistics provided by the American Heart Association, approximately 84 million people in this US suffer from some form of cardiovascular disease, leading to the death of about 2,200 people a day.
The exact causes of CVD are not identified. however, the most prevalent factors that cause CVD are aging, family history, unhealthy diet, lack of exercise, being overweight and smoking.
Epidemiological studies suggested that most people with CVD are also associated with atherosclerosis, a condition caused by long-term plaque buildup on artery walls, which can narrow the arteries and reduce blood flow through your arteries to the heart.
Some researchers suggested the promotion of the Western diet over the past few decades may have a strong implication on the rise of CVD.
Dr. Mirmiran P, the lead scientist, in the examination of the diet pattern and the risk of CVD in Iran, said, "During a mean 4.7 ± 1.4 years of follow-up, 57 participants experienced CVD-related events. In the fully adjusted model, we observed an increased risk of CVD-related events in the highest compared to the lowest tertile category of Western dietary pattern score (HR = 2.07, 95% CI = 1.03-4.18, P for trend = 0.01)".
And "the Western dietary pattern, characterized by higher loads of processed meats, salty snacks, sweets, and soft drinks, is a dietary risk factor for CVD in the Iranian population".
The results strongly indicated the increased risk of CVD in people who follow the Western diet pattern.
Turmeric is a perennial plant in the genus Curcuma, belonging to the family Zingiberaceae, native to tropical South Asia.
The herb has been used in traditional medicine as anti-oxidant, hypoglycemic, colorant, antiseptic, wound healing agent, and to treat flatulence, bloating, and appetite loss, ulcers, eczema, inflammations, etc.
In the urgency to discover a potential compound for the treatment of cardiovascular disease (CVD) associated with the largest mortality worldwide, scientists examined the cardiovascular protective properties of curcumin in CVDs.
According to the review, curcumin showed significant activity against the onset of CVDs, including cardiac hypertrophy, heart failure, drug-induced cardiotoxicity, myocardial infarction, atherosclerosis, abdominal aortic aneurysm, stroke, and diabetic cardiovascular complications.
In dyslipidemia, an important and common cardiovascular risk factor in the general population, researchers assessed the efficacy and safety of turmeric and curcumin in lowering blood lipids in patients at risk of cardiovascular disease (CVD), through searching the database of medical literature.
The comprehensive literature search conducted on PubMed, Embase, Ovid, Medline and Cochrane Library databases were to identify randomized controlled trials (published as of November 2016).
Based on the results of 7 eligible studies (649 patients) satisfied the guideline and criteria, researchers found that
* Turmeric and curcumin significantly reduced serum low-density lipoprotein cholesterol (LDL-C) levels as compared to those in the control group.
* Turmeric and curcumin also were effective in lowering serum total cholesterol (TC), levels in patients with metabolic syndrome.
* Turmeric extract has a greater effect on reducing serum TC levels compared to curcumin.
* Both turmeric and curcumin did not improve the serum high-density lipoprotein cholesterol (HDL-C).
* More importantly, turmeric and curcumin are safe, and no serious adverse events were reported in any of the included studies.
Dr. Qin S, the lead researcher wrote, "Turmeric and curcumin may protect patients at risk of CVD through improving serum lipid levels. Curcumin may be used as a well-tolerated dietary adjunct to conventional drugs".
Taken altogether, turmeric and its bioactive compound curcumin may be considered supplements for the prevention and treatment of cardiovascular disease, pending to the confirmation of the larger sample size and multicenter human study.
Intake of curcumin in the form of supplements should be taken with extreme care to prevent overdose acute liver toxicity.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Curcumin, the golden spice in treating cardiovascular diseases by Li H1, Sureda A2, Devkota HP3, Pittalà V4, Barreca D5, Silva AS6, Tewari D7, Xu S8, Nabavi SM. (PubMed)
(2) Efficacy and safety of turmeric and curcumin in lowering blood lipid levels in patients with cardiovascular risk factors: a meta-analysis of randomized controlled trials by Qin S1, Huang L1, Gong J1,2, Shen S1,2, Huang J1,2, Ren H2, Hu H. (PubMed)
(3) Western dietary pattern increases risk of cardiovascular disease in Iranian adults: a prospective population-based study by Mirmiran P1, Bahadoran Z2, Vakili AZ3, Azizi F. (PubMed)
Thursday, March 5, 2020
Herbal Ashwagandha Protects the Neurons Against Neurotoxicity
The central nervous system is a part of the nervous system of the brain and spinal cord with the function of integrates information it receives from for the entire nervous system, and control all the workings of the body.
Neurotoxicity is a form of toxicity that affects the structure or function of the central and/or peripheral nervous system, leading to damage to neurons and brain cells of the central nervous system.
In some cases, neurotoxicity can induce unpleasant symptoms of weakness in the limbs. altered sensation, tingling, and numbness in the limbs, headache, and loss of certain types of acute cognitive function.
However, in severe cases, neurotoxicity can cause vision loss, complete loss of memory and reduced cognitive function.
Some patients with neurotoxicity also experience uncontrollable obsessive and/or compulsive behavior and sexual dysfunction.
The blood-brain barrier (BBB) is composed of a network of vessels that form a structural and chemical barrier to protect the neuron's integrity and viability between the brain and systemic circulation.
BBB permeability is the functions of neurons that involve the extracellular matrix, and non-neuronal cells including astrocytes, pericytes, and vascular endothelial cells,... to protect the brain from exposure peripheral organs that toxic to neurons.
BBB dysfunction has been found to be induced by neuronal dysfunction, neuroinflammation, and neurodegeneration.
BBB permeability alternation can be caused by brain injury, ischemic stroke, multiple sclerosis (MS), Parkinson's disease, Alzheimer's disease, and major depression, leading to significant neuronal dysfunction.
Ashwagandha also is known as Withania somnifera is a nightshade plant in the genus of Withania, belonging to the family Solanaceae, native to the dry parts of India, North Africa, Middle East, and the Mediterranean.
The herbal medicine has been considered as Indian ginseng and used in Ayurvedic medicine over 3000 years to treat tumors and tubercular glands, carbuncles, memory loss, and ulcers and considered as anti-stress, cognition-facilitating, anti-inflammatory, and anti-aging herbal medicine.
On finding a potent compound that processes the neuroprotective effect, researchers examined the effects of the blood-brain barrier permeability of withanamides in W.somnifera fruit extract in a mice model.
In vitro, withanamides, the primary active constituents in W.somnifera fruit extract exhibited neuroprotective effects against β-amyloid-induced cytotoxicity in neuronal cell culture.
According to the tested assays, the effect of withanamides was attributed to four major withanamides isolated from W.somnifera fruit extract found in the brain and blood of mice administered with W.somnifera extract.
In other words, certain chemical constituents can pass through the blood-brain barrier to protect the brain against neuron deteriorate that lead to neurons' dysfunction.
More precisely, W.somnifera fruit extract may be used as a preventive or therapeutic botanical drug for stress-induced neurological disorders.
Taken altogether, Ashwagandha may be considered a functional herb for neurological diseases including Parkinson's disease, Alzheimer's disease, pending to the result of larger sample size and multicenter study
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Blood-brain barrier permeability of bioactive withanamides present in Withaniasomnifera fruit extract by Vareed SK1, Bauer AK, Nair KM, Liu Y, Jayaprakasam B, Nair MG. (PubMed)
Neurotoxicity is a form of toxicity that affects the structure or function of the central and/or peripheral nervous system, leading to damage to neurons and brain cells of the central nervous system.
In some cases, neurotoxicity can induce unpleasant symptoms of weakness in the limbs. altered sensation, tingling, and numbness in the limbs, headache, and loss of certain types of acute cognitive function.
However, in severe cases, neurotoxicity can cause vision loss, complete loss of memory and reduced cognitive function.
Some patients with neurotoxicity also experience uncontrollable obsessive and/or compulsive behavior and sexual dysfunction.
The blood-brain barrier (BBB) is composed of a network of vessels that form a structural and chemical barrier to protect the neuron's integrity and viability between the brain and systemic circulation.
BBB permeability is the functions of neurons that involve the extracellular matrix, and non-neuronal cells including astrocytes, pericytes, and vascular endothelial cells,... to protect the brain from exposure peripheral organs that toxic to neurons.
BBB dysfunction has been found to be induced by neuronal dysfunction, neuroinflammation, and neurodegeneration.
BBB permeability alternation can be caused by brain injury, ischemic stroke, multiple sclerosis (MS), Parkinson's disease, Alzheimer's disease, and major depression, leading to significant neuronal dysfunction.
Ashwagandha also is known as Withania somnifera is a nightshade plant in the genus of Withania, belonging to the family Solanaceae, native to the dry parts of India, North Africa, Middle East, and the Mediterranean.
The herbal medicine has been considered as Indian ginseng and used in Ayurvedic medicine over 3000 years to treat tumors and tubercular glands, carbuncles, memory loss, and ulcers and considered as anti-stress, cognition-facilitating, anti-inflammatory, and anti-aging herbal medicine.
On finding a potent compound that processes the neuroprotective effect, researchers examined the effects of the blood-brain barrier permeability of withanamides in W.somnifera fruit extract in a mice model.
In vitro, withanamides, the primary active constituents in W.somnifera fruit extract exhibited neuroprotective effects against β-amyloid-induced cytotoxicity in neuronal cell culture.
According to the tested assays, the effect of withanamides was attributed to four major withanamides isolated from W.somnifera fruit extract found in the brain and blood of mice administered with W.somnifera extract.
In other words, certain chemical constituents can pass through the blood-brain barrier to protect the brain against neuron deteriorate that lead to neurons' dysfunction.
More precisely, W.somnifera fruit extract may be used as a preventive or therapeutic botanical drug for stress-induced neurological disorders.
Taken altogether, Ashwagandha may be considered a functional herb for neurological diseases including Parkinson's disease, Alzheimer's disease, pending to the result of larger sample size and multicenter study
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Blood-brain barrier permeability of bioactive withanamides present in Withaniasomnifera fruit extract by Vareed SK1, Bauer AK, Nair KM, Liu Y, Jayaprakasam B, Nair MG. (PubMed)
Wednesday, March 4, 2020
Turmeric, the Natural Treatment for Hyperlipidemia with No Side Effects
Hyperlipidemia is a chronic condition of abnormally high levels of any or all lipoproteins in the bloodstream, including cholesterol and triglycerides.
The condition is normally known as high blood cholesterol in the general population.
People with hyperlipidemia are asymptomatic. Over time, the fat collection in the arteries accompanied by calcium or other substances form plague, leading to narrowing arteries and reduced function of the arteries to transport oxygen-rich blood to the parts of the body.
According to the statistics provided by the CDC, in 2015–2016, more than 12% of adults age 20 and older had total cholesterol higher than 240 mg/dL, and more than 18% had high-density lipoprotein (HDL, or “good”) cholesterol levels less than 40 mg/dL.
Believe it or not, about half of the U.S. adults (55%, or 43 million) are currently taking medicine associated with lower blood cholesterol.
There are many risk factors that cause the onset of hyperlipidemia, such as people with diabetes, being overweight gain, physical activity, and smoking.
Some researchers suggested the promotion of a high-fat diet over the past decades may be one of the silent cause of hyperlipidemia in the Western world.
Dr. Charles Desmarchelier in the examined the risk of high blood cholesterol in a high-fat diet model said, "Mice on Western diet showed increased plasma cholesterol levels, associated with the higher dietary cholesterol supply, yet, significantly reduced cholesterol levels were found in intestine and liver".
And, "(The) intestine and liver react to a high dietary fat intake by activation of de novo cholesterol synthesis and other cholesterol-saving mechanisms, as well as with major changes in phospholipid metabolism, to accommodate to the fat load'.
Turmeric is a perennial plant in the genus Curcuma, belonging to the family Zingiberaceae, native to tropical South Asia.
The herb has been used in traditional medicine as anti-oxidant, hypoglycemic, antiseptic, wound healing agent, and to treat flatulence, bloating, and appetite loss, ulcers, eczema, inflammations, etc.
With an aim to find a natural ingredient for the treatment of hyperlipidemia, researchers investigated the effects of curcumin on hyperlipidemia and hepatic steatosis in high-fructose-fed Wistar rats.
The study included 40 male Wistar rats divided into four groups with 10 rats in each. Two groups were fed with a standard rodent diet and the other two with a 60% high-fructose diet for 10 weeks. Curcumin (200 mg/kg body weight) was administered along with the diets simultaneously to each of the aforementioned diet groups.
After 10 weeks of the experiment, researchers found that curcumin decreased the levels of hyperlipidemia observed by reducing body weight, liver weight, adipose weight.
The plasma levels of triglyceride by inhibited the proteins associated with fat cell fat metabolism, lipid ratios and increased HDL-C (28.4 ± 4.5 mg/dL) in fructose-fed rats were also lower by the injection of curcumin
Furthermore, curcumin also suppressed the lipogenic enzymes involved in regulating lipogenesis in fat cells.
Taken altogether, turmeric processed a high amount of curcumin may be used for the prevention and treatment of hyperlipidemia, pending to the confirmation of the larger sample size and multicenter human study.
Intake of turmeric in the form of supplements should be taken with extreme care to prevent overdose acute liver toxicity.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Curcumin inhibits hyperlipidemia and hepatic fat accumulation in high-fructose-fed male Wistar rats by Maithilikarpagaselvi N1, Sridhar MG1, Swaminathan RP2, Sripradha R1, Badhe B. (PubMed)
(2) Highly bioavailable micellar curcuminoids accumulate in blood, are safe and do not reduce blood lipids and inflammation markers in moderately hyperlipidemic individuals by Kocher A1, Bohnert L1, Schiborr C1, Frank J, (PubMed)
(3) C57Bl/6 N mice on a western diet display reduced intestinal and hepatic cholesterol levels despite a plasma hypercholesterolemia by Charles Desmarchelier,
1 Christoph Dahlhoff,1,2 Sylvia Keller,3 Manuela Sailer,1Gerhard Jahreis,3 and Hannelore Daniel. (PMC)
The condition is normally known as high blood cholesterol in the general population.
People with hyperlipidemia are asymptomatic. Over time, the fat collection in the arteries accompanied by calcium or other substances form plague, leading to narrowing arteries and reduced function of the arteries to transport oxygen-rich blood to the parts of the body.
According to the statistics provided by the CDC, in 2015–2016, more than 12% of adults age 20 and older had total cholesterol higher than 240 mg/dL, and more than 18% had high-density lipoprotein (HDL, or “good”) cholesterol levels less than 40 mg/dL.
Believe it or not, about half of the U.S. adults (55%, or 43 million) are currently taking medicine associated with lower blood cholesterol.
There are many risk factors that cause the onset of hyperlipidemia, such as people with diabetes, being overweight gain, physical activity, and smoking.
Some researchers suggested the promotion of a high-fat diet over the past decades may be one of the silent cause of hyperlipidemia in the Western world.
Dr. Charles Desmarchelier in the examined the risk of high blood cholesterol in a high-fat diet model said, "Mice on Western diet showed increased plasma cholesterol levels, associated with the higher dietary cholesterol supply, yet, significantly reduced cholesterol levels were found in intestine and liver".
And, "(The) intestine and liver react to a high dietary fat intake by activation of de novo cholesterol synthesis and other cholesterol-saving mechanisms, as well as with major changes in phospholipid metabolism, to accommodate to the fat load'.
Turmeric is a perennial plant in the genus Curcuma, belonging to the family Zingiberaceae, native to tropical South Asia.
The herb has been used in traditional medicine as anti-oxidant, hypoglycemic, antiseptic, wound healing agent, and to treat flatulence, bloating, and appetite loss, ulcers, eczema, inflammations, etc.
With an aim to find a natural ingredient for the treatment of hyperlipidemia, researchers investigated the effects of curcumin on hyperlipidemia and hepatic steatosis in high-fructose-fed Wistar rats.
The study included 40 male Wistar rats divided into four groups with 10 rats in each. Two groups were fed with a standard rodent diet and the other two with a 60% high-fructose diet for 10 weeks. Curcumin (200 mg/kg body weight) was administered along with the diets simultaneously to each of the aforementioned diet groups.
After 10 weeks of the experiment, researchers found that curcumin decreased the levels of hyperlipidemia observed by reducing body weight, liver weight, adipose weight.
The plasma levels of triglyceride by inhibited the proteins associated with fat cell fat metabolism, lipid ratios and increased HDL-C (28.4 ± 4.5 mg/dL) in fructose-fed rats were also lower by the injection of curcumin
Furthermore, curcumin also suppressed the lipogenic enzymes involved in regulating lipogenesis in fat cells.
Taken altogether, turmeric processed a high amount of curcumin may be used for the prevention and treatment of hyperlipidemia, pending to the confirmation of the larger sample size and multicenter human study.
Intake of turmeric in the form of supplements should be taken with extreme care to prevent overdose acute liver toxicity.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Curcumin inhibits hyperlipidemia and hepatic fat accumulation in high-fructose-fed male Wistar rats by Maithilikarpagaselvi N1, Sridhar MG1, Swaminathan RP2, Sripradha R1, Badhe B. (PubMed)
(2) Highly bioavailable micellar curcuminoids accumulate in blood, are safe and do not reduce blood lipids and inflammation markers in moderately hyperlipidemic individuals by Kocher A1, Bohnert L1, Schiborr C1, Frank J, (PubMed)
(3) C57Bl/6 N mice on a western diet display reduced intestinal and hepatic cholesterol levels despite a plasma hypercholesterolemia by Charles Desmarchelier,
1 Christoph Dahlhoff,1,2 Sylvia Keller,3 Manuela Sailer,1Gerhard Jahreis,3 and Hannelore Daniel. (PMC)
Dietary Patterns in the Risk of Metabolic Syndrome
A dietary pattern is the measurement of the quantity, variety, or combination of different foods and beverages in a diet as well as the frequency of the foods are habitually consumed.
Most common dietary patterns are
* The traditional diet, Wikipedia wrote, "Traditional foods are foods and dishes that are passed through generations or which have been consumed many generations. Traditional foods and dishes are traditional in nature, and may have a historic precedent in a national dish, regional cuisine or local cuisine".
* The Western diet is a standard American diet (SAD) associated with high intakes of red meat, processed meat, pre-packaged and refined foods, fried foods, high-fat dairy products, high salt, and sugar.foods.
Metabolic syndrome is a cluster of conditions associated with the increased risk of cardiovascular disease and diabetes.
The health problems found in the group include too much fat around the waist, elevated blood pressure, high triglycerides, elevated blood sugar, and low HDL cholesterol.
In other words, if you have 3 of the conditions in the group, your risk of CVD and diabetes are increased substantially compared to those who have less.
According to the statistics, approximately 30% of people in the US are living with metabolic syndrome.
Believe it or not, among US adults aged 18 years or older, the prevalence of metabolic syndrome rose by more than 35% from 1988–1994 to 2007–2012, increasing from 25.3% to 34.2%.
Besides the aforementioned conditions, risks of metabolic syndrome may include age, family history, physical, inactivity, and women with polycystic ovary syndrome, epidemiologically.
As of today, the treatment of metabolic syndrome commonly is prescribed medications to reduce blood pressure, cholesterol, and/or blood sugar with an aim to reduce the risk of developing further health complications and improve quality of life.
On finding a potent ingredient for the treatment of metabolic syndrome, researchers investigated the association between major dietary patterns, including several eating habits.
The cross-sectional study included a total of 425 subjects 35 to 55 y of age, using a food-frequency questionnaire in 5 dietary patterns.
Five major dietary patterns were examined by the Isfahan University of Medical Sciences, including
* A western pattern (high in sweets, butter, soda, mayonnaise, sugar, cookies, the tail of a lamb, hydrogenated fat, and eggs),
* A prudent pattern (high in fish, peas, honey, nuts, juice, dry fruits, vegetable oil, liver and organic meat, and coconuts and low in hydrogenated fat and non-leafy vegetables),
* A vegetarian pattern (high in potatoes, legumes, fruits rich in vitamin C, rice, green leafy vegetables, and fruits rich in vitamin A),
* A high-fat dairy pattern (high in high-fat yogurt and high-fat milk and low in low-fat yogurt, peas, and bread), and
* A chicken and plant pattern (high in chicken, fruits rich in vitamin A, green leafy vegetables, and mayonnaise and low in the beef, liver, and organic meat).
Based on the tested differentiation and adjusting to other confounders,
* The western pattern has a strong and negative impact on increasing triacylglycerol and blood pressure.
* The prudent pattern was positively associated a low high-density lipoprotein cholesterol levels compared to other dietary patterns.
* However, the vegetarian dietary pattern was inversely associated with a risk of an abnormal fasting blood glucose level.
Collectively, all dietary patterns are associated with positive or negative in increasing or decreasing the risk of metabolic syndrome.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You. How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Relationship between major dietary patterns and metabolic syndrome among individuals with impaired glucose tolerance by Amini M1, Esmaillzadeh A, Shafaeizadeh S, Behrooz J, Zare M. (PubMed)
Most common dietary patterns are
* The traditional diet, Wikipedia wrote, "Traditional foods are foods and dishes that are passed through generations or which have been consumed many generations. Traditional foods and dishes are traditional in nature, and may have a historic precedent in a national dish, regional cuisine or local cuisine".
* The Western diet is a standard American diet (SAD) associated with high intakes of red meat, processed meat, pre-packaged and refined foods, fried foods, high-fat dairy products, high salt, and sugar.foods.
Metabolic syndrome is a cluster of conditions associated with the increased risk of cardiovascular disease and diabetes.
The health problems found in the group include too much fat around the waist, elevated blood pressure, high triglycerides, elevated blood sugar, and low HDL cholesterol.
In other words, if you have 3 of the conditions in the group, your risk of CVD and diabetes are increased substantially compared to those who have less.
According to the statistics, approximately 30% of people in the US are living with metabolic syndrome.
Believe it or not, among US adults aged 18 years or older, the prevalence of metabolic syndrome rose by more than 35% from 1988–1994 to 2007–2012, increasing from 25.3% to 34.2%.
Besides the aforementioned conditions, risks of metabolic syndrome may include age, family history, physical, inactivity, and women with polycystic ovary syndrome, epidemiologically.
As of today, the treatment of metabolic syndrome commonly is prescribed medications to reduce blood pressure, cholesterol, and/or blood sugar with an aim to reduce the risk of developing further health complications and improve quality of life.
On finding a potent ingredient for the treatment of metabolic syndrome, researchers investigated the association between major dietary patterns, including several eating habits.
The cross-sectional study included a total of 425 subjects 35 to 55 y of age, using a food-frequency questionnaire in 5 dietary patterns.
Five major dietary patterns were examined by the Isfahan University of Medical Sciences, including
* A western pattern (high in sweets, butter, soda, mayonnaise, sugar, cookies, the tail of a lamb, hydrogenated fat, and eggs),
* A prudent pattern (high in fish, peas, honey, nuts, juice, dry fruits, vegetable oil, liver and organic meat, and coconuts and low in hydrogenated fat and non-leafy vegetables),
* A vegetarian pattern (high in potatoes, legumes, fruits rich in vitamin C, rice, green leafy vegetables, and fruits rich in vitamin A),
* A high-fat dairy pattern (high in high-fat yogurt and high-fat milk and low in low-fat yogurt, peas, and bread), and
* A chicken and plant pattern (high in chicken, fruits rich in vitamin A, green leafy vegetables, and mayonnaise and low in the beef, liver, and organic meat).
Based on the tested differentiation and adjusting to other confounders,
* The western pattern has a strong and negative impact on increasing triacylglycerol and blood pressure.
* The prudent pattern was positively associated a low high-density lipoprotein cholesterol levels compared to other dietary patterns.
* However, the vegetarian dietary pattern was inversely associated with a risk of an abnormal fasting blood glucose level.
Collectively, all dietary patterns are associated with positive or negative in increasing or decreasing the risk of metabolic syndrome.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You. How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Relationship between major dietary patterns and metabolic syndrome among individuals with impaired glucose tolerance by Amini M1, Esmaillzadeh A, Shafaeizadeh S, Behrooz J, Zare M. (PubMed)
Tuesday, March 3, 2020
The Science Base of Herbs in Induced Weight Loss and Weight Maintenance
Overweight and obesity have reached epidemic proportions in many countries, causing economic burden in increased absentees in the workplaces and funding for the health care system in dealing with obesity-related disorders such as diabetes, hypertension, and cardiovascular diseases(1).
One of six Malaysian are either extremely overweight or obese, according to Datin Paduka Santha Kumari, chairman of the Selangor branch of the Malaysian Diabetes Association and the global health observatory, at least 2.8 million people die each year as a result of being overweight or obese, and an estimated 35.8 million (2.3%) of global burden of disease is caused by overweight or obesity(2).
Epidemiological studies, linking herbal medicine, foods, and vitamins in preventing and treating these diseases have been inconclusive(a)
Some researchers suggested that the intake of certain herbal medicine may enhance appetite suppression.
According to the Georgetown University Medical Center, the appetite of average daily food intake was decreased only with the herbal formulation, regardless number of single-ingredient in comparison to the effectiveness among herbal formulation and a commonly available(3).
Other researchers insisted that using herbs and supplements to induce weight loss should be taken with care, as a considerable number of reports have been published on hepatotoxicity associated to intake of herbal products(4)(5)(6)(7).
The College of Medicine, The Ohio State University insisted that various dietary, lifestyle and psychological factors are involved in the etiology of Prameha, in initiated disturbances of fat and carbohydrate metabolism in overweight and obese(8), without effective management, obtaining a workable weight loss plan may be extremely difficult.
1. Ginseng
Ginseng is a slow-growing perennial plant with fleshy roots, the genus Panax, belongings to the family Araliaceae. Depending on the climate where it grows, ginseng can be classified mainly into Panax ginseng Asian ginseng (root), Red ginseng, wild ginseng, American ginseng (root)(14).
In 10 obese middle-aged Korean women who took Panax ginseng extracts for 8 wk, showed effectively in influence on gut microbiota in promoting weight loss but depending on the composition of gut microbiota prior to ginseng intake(15).
In mice fed with a high-fat diet, ginseng saponin and ginsenosides exerted anti-obesity effects via the modulation of physiological lipid metabolism in vivo or intracellular signaling in cell culture systems and abnormal physiology of leptin, insulin, and adiponectin in energy and lipid metabolism(16).
2. Zingiber Officinale(Ginger
Ginger (Zingiber officinale) or ginger root is the genus Zingiber, belongings to the family Zingiberaceae, native to Tamil, used in traditional and Chinese medicine to treat dyspepsia, gastroparesis, constipation, edema, difficult urination, colic, etc.(17).
According to the Tehran University of Medical Sciences, Slimax (extract of several plants including Zingiber officinale and Bofutsushosan) showed a significant decrease in body weight or inhibited weight gain(18).
Application of composition of a multi-ingredients supplement containing primarily raspberry ketone, caffeine, capsaicin, garlic, ginger, and Citrus aurantium, also improved body composition, waist, and hip girth, in an eight-week diet and exercise weight loss program(19).
In a comparison of the weight loss effect of Orlistat, a pharmacological agent promoting weight loss, injection of ginger (Zingiber officinale Roscoe, Zingiberacae) in male albino rats induced a great ability to reduce body weight without inhibiting pancreatic lipase level, or affected bilirubin concentration, and increased peroxisomal catalase level and HDL-cholesterol(20).
3. Cissus quadrangularis (CQ)
Cissus quadrangularis is an ancient herb used to treat a variety of indications, belongings to the grape family, probably native to India or Sri Lanka.
In a randomized, double-blind, placebo-controlled design study involving 123 overweight and obese persons (47.2% male; 52.8% female; ages 19-50). conducted by University of Yaoundé I, Cissus quadrangularis, application of cissus quadrangularis displayed a statistically significant net reductions in weight and central obesity, as well as normalized metabolic syndrome(21).
In comparison of the efficacy of Cissus quadrangularis-only and Cissusquadrangularis/Irvingia gabonensis combination, on weight loss in overweight and obese human subjects, cissus quadrangularis-only group showed significant reductions on all variables in compared to the placebo group, but lower effects in compared to the cissus quadrangularis/Irvingia gabonensis combination group(22)
Intake of CQR-300, a proprietary extract of Cissusquadrangularis, also demonstrated a significant deceased weight and blood glucose levels, serum lipids, thus improving cardiovascular risk factors, according to the University of Yaoundé I,(23).
4. Sambucus nigra
Elder also known as Common Elder, is a shrub or small tree of the genus Sambucus of 30 specie, belongings to the family Adoxaceae, native to the temperate-to-subtropical regions of both the Northern Hemisphere and the Southern Hemisphere, used in traditional and herbal medicine to treat constipation, colic, diarrhea, colds, flu, bronchial and upper-respiratory, irritation of the skin, rheumatism, etc.
The composition of supplement with Sambucus nigra and Asparagus officinalis study expressed effectiveness in reduced weight, blood pressure, enhanced physical and emotional well-being and quality of life(24).
The Tehran University of Medical Sciences, Sambucus nigra study, also demonstrated a significant decrease in body weight in numbers of animal studies(25).
5. Asparagus officinalis
Asparagus is a flowering plant belonging to species the genus Asparagus, native to the western coasts of northern Spain, north to Ireland, Great Britain, and northwest Germany, northern Africa, and western Asia, used from early times as a vegetable and medicine, because of its delicate flavor and diuretic properties(26).
Asparagus officinalis L. powder tablets provided 19 mg saponins per day in overweight and obese subjects reduced mean weight, blood pressure, and enhanced physical and emotional well-being and the quality of life with the rate of very good or good in most of the completers(27).
In 12 weeks supplementation of a botanical extract-based weight loss formula, including Asparagus, researchers at the Poznan University of Medical Science indicated that the formula exerts a significant change of the body composition improvement index (BCI), induces greater weight loss than placebo, probably through a concurrently performed exercise program recommended strategy for lifestyle modification(28).
6. Slimax
Slimax (extract of several plants including officinale and Bofutsushosan), in the reviews of the database of studies published, researchers showed that intake of Slimax indices a significant decrease in body weight(29).
In 41 animal studies, the formula was found to be effective in significant induced weight loss or inhibited weight gain(29).
Taken altogether, the above herbs may be effective in enhanced weight loss through suppression of appetite and improvement of syndrome induced by overweight and obesity. However, the intake of herbal supplements and composition should only be prescribed by herbal doctors.
FDA banned Ephedra (Ma Huang) weight loss products in 2004
[Ma Huang is also known as ephedra. The acrid, slightly bitter and warm herb has been used in TCM to promote urination and sweating and rid of cold, soothe wheezing asthma, ...., by enhancing the functions of lung and bladder channels(9).
According to Dongguk University, certain chemicals found in Ephera showed an association with changes of BW and BMI through alteration of gut microbiota varied by indigenous microbiota of tested subject(10).
The combined study of a low-calorie diet and Ephera, in 125 otherwise healthy obese women, showed effectively in reducing BMI. RMR changes not compensated for by the herbal medicines tried.
Resting metabolic rate (RMR) change seemed to be affected by constitution and body composition rather than by medicine(11). The Dongeui University study of composition GGEx18( Laminaria japonica, Rheum palmatum, and Ephedra sinica) in high fat diet-induced obese mice suggested that GGEx18 improves obesity through skeletal muscle AMPK and AMPK-stimulated expression of PPARα and its target enzymes for fatty acid oxidation, through inhibited lipid accumulation, and similar activation of genes(12).
Please note that due to its adverse reactions of palpitations, stress, headache and insomnia and stroke, heart attacks, cardiac arrhythmias, seizures, and psychotic effect, the FDA banned the product on 2004, the Dutch Inspectorate for Health Care and the Ministry of Health in Canada have recently requested a market recall of some ephedrine-containing herbal products in response to above adverse reactions. In the Netherlands, the status of Ephedra-containing products is currently reconsidered(13)]
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Home page http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.
References
(1) Rising Burden of Obesity in Asia by Ambady Ramachandran and Chamukuttan Snehalatha(Journey of Obesity)
(2) Obesity - Situation and trends(WHO)
(3) Influence of a combination of herbs on appetite suppression and weight loss in rats by Talpur NA1, Echard BW, Manohar V, Preuss HG.(PubMed)
(4) [Hepatotoxicity induced by herbs and medicines used to induce weight loss].[Article in Spanish]by Herrera S1, Bruguera M.(PubMed)
(5) A case report of adult lead toxicity following use of Ayurvedic herbal medication by Breeher L1, Gerr F, Fuortes L.(PubMed)
(6) [Chronic lead intoxication associated with Ayurvedic medication].[Article in Dutch] by Kanen BL1, Perenboom RM.(PubMed)
(7) Potential toxicity of caffeine when used as a dietary supplement for weight loss by Pendleton M1, Brown S, Thomas C, Odle B.(PubMed)
(8) Multinutrient supplement containing ephedra and caffeine causes weight loss and improves metabolic risk factors in obese women: a randomized controlled trial by Hackman RM1, Havel PJ, Schwartz HJ, Rutledge JC, Watnik MR, Noceti EM, Stohs SJ, Stern JS, Keen CL.(PubMed)
(9) Ma Huang(Popular Chinese herbs)
(10) Prameha in Ayurveda: correlation with obesity, metabolic syndrome, and diabetes mellitus. Part 2--management of Prameha by Sharma H1, Chandola HM.(PubMed)
(11) Effect of herbal Ephedra sinica and Evodia rutaecarpa on body composition and resting metabolic rate: a randomized, double-blind clinical trial in Korean premenopausal women by Kim HJ1, Park JM, Kim JA, Ko BP(PubMed)
(12) The herbal composition GGEx18 from Laminaria japonica, Rheum palmatum, and Ephedra sinica reduces obesity via skeletal muscle AMPK and PPARα by Shin SS1, Park D, Lee HY, Hong Y, Choi J, Oh J, Lee H, Lee HR, Kim MR, Shen ZB, Cui HH, Yoon M.(PubMed)
(13) [Ephedrine and ephedra in weight loss products and other preparations].[Article in Dutch] by van der Hooft CS1, Stricker BH.(PubMed)
(14) Ginseng, Asian (Panax ginseng) and Ginseng, North America(Popular Chinese Herbs)
(15) Influence of Panax ginseng on obesity and gut microbiota in obese middle-aged Korean women by Song MY1, Kim BS2, Kim H(PubMed)
(16) Lipid metabolic effect of Korean red ginseng extract in mice fed on a high-fat diet by Song YB1, An YR, Kim SJ, Park HW, Jung JW, Kyung JS, Hwang SY, Kim YS.(PubMed)
(17) Popular #Herbs - #Ginger (Zingiber officinale)(Popular Chinese herbs)
(18) A systematic review of the efficacy and safety of herbal medicines used in the treatment of obesity by Hasani-Ranjbar S1, Nayebi N, Larijani B, Abdollahi M.(PubMed)
(19) Eight weeks of supplementation with a multi-ingredient weight lossproduct enhances body composition, reduces hip and waist girth, and increases energy levels in overweight men and women by Lopez HL1, Ziegenfuss TN, Hofheins JE, Habowski SM, Arent SM, Weir JP, Ferrando AA.(PubMed)
(20) Comparative evaluation of the efficacy of ginger and orlistat on obesity management, pancreatic lipase and liver peroxisomal catalase enzyme in male albino rats by Mahmoud RH1, Elnour WA.(PubMed)
(21) The use of a Cissus quadrangularis formulation in the management of weight loss and metabolic syndrome by Oben J1, Kuate D, Agbor G, Momo C, Talla X.(PubMed)
(22) The use of a Cissus quadrangularis/Irvingia gabonensis combination in the management of weight loss: a double-blind placebo-controlled study. by Oben JE1, Ngondi JL, Momo CN, Agbor GA, Sobgui CS.(PubMed)
(23) The effect of Cissus quadrangularis (CQR-300) and a Cissusformulation (CORE) on obesity and obesity-induced oxidative stress by Oben JE1, Enyegue DM, Fomekong GI, Soukontoua YB, Agbor GA.(PubMed)
(24) An observational study and quantification of the actives in a supplement with Sambucus nigra and Asparagus officinalis used for weight reduction by Chrubasik C1, Maier T, Dawid C, Torda T, Schieber A, Hofmann T, Chrubasik S.(PubMed)
(25) A systematic review of the efficacy and safety of herbal medicines used in the treatment of obesity by Hasani-Ranjbar S1, Nayebi N, Larijani B, Abdollahi M(PubMed)
(26) #Healthy #Foods - Vegetables - Asparagus (Asparagus officinalis)(health tips for better living and living health)
(27) An observational study and quantification of the actives in a supplement with Sambucus nigra and Asparagus officinalis used for weight reduction by Chrubasik C1, Maier T, Dawid C, Torda T, Schieber A, Hofmann T, Chrubasik S.(PubMed)
(28) Efficacy of 12 weeks supplementation of a botanical extract-based weight loss formula on body weight, body composition and blood chemistry in healthy, overweight subjects--a randomised double-blind placebo-controlled clinical trial by Opala T1, Rzymski P, Pischel I, Wilczak M, Wozniak J.(PubMed)
(29) A systematic review of the efficacy and safety of herbal medicines used in the treatment of obesity by Hasani-Ranjbar S1, Nayebi N, Larijani B, Abdollahi M.(PubMed)
One of six Malaysian are either extremely overweight or obese, according to Datin Paduka Santha Kumari, chairman of the Selangor branch of the Malaysian Diabetes Association and the global health observatory, at least 2.8 million people die each year as a result of being overweight or obese, and an estimated 35.8 million (2.3%) of global burden of disease is caused by overweight or obesity(2).
Epidemiological studies, linking herbal medicine, foods, and vitamins in preventing and treating these diseases have been inconclusive(a)
Some researchers suggested that the intake of certain herbal medicine may enhance appetite suppression.
According to the Georgetown University Medical Center, the appetite of average daily food intake was decreased only with the herbal formulation, regardless number of single-ingredient in comparison to the effectiveness among herbal formulation and a commonly available(3).
Other researchers insisted that using herbs and supplements to induce weight loss should be taken with care, as a considerable number of reports have been published on hepatotoxicity associated to intake of herbal products(4)(5)(6)(7).
The College of Medicine, The Ohio State University insisted that various dietary, lifestyle and psychological factors are involved in the etiology of Prameha, in initiated disturbances of fat and carbohydrate metabolism in overweight and obese(8), without effective management, obtaining a workable weight loss plan may be extremely difficult.
1. Ginseng
Ginseng is a slow-growing perennial plant with fleshy roots, the genus Panax, belongings to the family Araliaceae. Depending on the climate where it grows, ginseng can be classified mainly into Panax ginseng Asian ginseng (root), Red ginseng, wild ginseng, American ginseng (root)(14).
In 10 obese middle-aged Korean women who took Panax ginseng extracts for 8 wk, showed effectively in influence on gut microbiota in promoting weight loss but depending on the composition of gut microbiota prior to ginseng intake(15).
In mice fed with a high-fat diet, ginseng saponin and ginsenosides exerted anti-obesity effects via the modulation of physiological lipid metabolism in vivo or intracellular signaling in cell culture systems and abnormal physiology of leptin, insulin, and adiponectin in energy and lipid metabolism(16).
2. Zingiber Officinale(Ginger
Ginger (Zingiber officinale) or ginger root is the genus Zingiber, belongings to the family Zingiberaceae, native to Tamil, used in traditional and Chinese medicine to treat dyspepsia, gastroparesis, constipation, edema, difficult urination, colic, etc.(17).
According to the Tehran University of Medical Sciences, Slimax (extract of several plants including Zingiber officinale and Bofutsushosan) showed a significant decrease in body weight or inhibited weight gain(18).
Application of composition of a multi-ingredients supplement containing primarily raspberry ketone, caffeine, capsaicin, garlic, ginger, and Citrus aurantium, also improved body composition, waist, and hip girth, in an eight-week diet and exercise weight loss program(19).
In a comparison of the weight loss effect of Orlistat, a pharmacological agent promoting weight loss, injection of ginger (Zingiber officinale Roscoe, Zingiberacae) in male albino rats induced a great ability to reduce body weight without inhibiting pancreatic lipase level, or affected bilirubin concentration, and increased peroxisomal catalase level and HDL-cholesterol(20).
3. Cissus quadrangularis (CQ)
Cissus quadrangularis is an ancient herb used to treat a variety of indications, belongings to the grape family, probably native to India or Sri Lanka.
In a randomized, double-blind, placebo-controlled design study involving 123 overweight and obese persons (47.2% male; 52.8% female; ages 19-50). conducted by University of Yaoundé I, Cissus quadrangularis, application of cissus quadrangularis displayed a statistically significant net reductions in weight and central obesity, as well as normalized metabolic syndrome(21).
In comparison of the efficacy of Cissus quadrangularis-only and Cissusquadrangularis/Irvingia gabonensis combination, on weight loss in overweight and obese human subjects, cissus quadrangularis-only group showed significant reductions on all variables in compared to the placebo group, but lower effects in compared to the cissus quadrangularis/Irvingia gabonensis combination group(22)
Intake of CQR-300, a proprietary extract of Cissusquadrangularis, also demonstrated a significant deceased weight and blood glucose levels, serum lipids, thus improving cardiovascular risk factors, according to the University of Yaoundé I,(23).
4. Sambucus nigra
Elder also known as Common Elder, is a shrub or small tree of the genus Sambucus of 30 specie, belongings to the family Adoxaceae, native to the temperate-to-subtropical regions of both the Northern Hemisphere and the Southern Hemisphere, used in traditional and herbal medicine to treat constipation, colic, diarrhea, colds, flu, bronchial and upper-respiratory, irritation of the skin, rheumatism, etc.
The composition of supplement with Sambucus nigra and Asparagus officinalis study expressed effectiveness in reduced weight, blood pressure, enhanced physical and emotional well-being and quality of life(24).
The Tehran University of Medical Sciences, Sambucus nigra study, also demonstrated a significant decrease in body weight in numbers of animal studies(25).
5. Asparagus officinalis
Asparagus is a flowering plant belonging to species the genus Asparagus, native to the western coasts of northern Spain, north to Ireland, Great Britain, and northwest Germany, northern Africa, and western Asia, used from early times as a vegetable and medicine, because of its delicate flavor and diuretic properties(26).
Asparagus officinalis L. powder tablets provided 19 mg saponins per day in overweight and obese subjects reduced mean weight, blood pressure, and enhanced physical and emotional well-being and the quality of life with the rate of very good or good in most of the completers(27).
In 12 weeks supplementation of a botanical extract-based weight loss formula, including Asparagus, researchers at the Poznan University of Medical Science indicated that the formula exerts a significant change of the body composition improvement index (BCI), induces greater weight loss than placebo, probably through a concurrently performed exercise program recommended strategy for lifestyle modification(28).
6. Slimax
Slimax (extract of several plants including officinale and Bofutsushosan), in the reviews of the database of studies published, researchers showed that intake of Slimax indices a significant decrease in body weight(29).
In 41 animal studies, the formula was found to be effective in significant induced weight loss or inhibited weight gain(29).
Taken altogether, the above herbs may be effective in enhanced weight loss through suppression of appetite and improvement of syndrome induced by overweight and obesity. However, the intake of herbal supplements and composition should only be prescribed by herbal doctors.
FDA banned Ephedra (Ma Huang) weight loss products in 2004
[Ma Huang is also known as ephedra. The acrid, slightly bitter and warm herb has been used in TCM to promote urination and sweating and rid of cold, soothe wheezing asthma, ...., by enhancing the functions of lung and bladder channels(9).
According to Dongguk University, certain chemicals found in Ephera showed an association with changes of BW and BMI through alteration of gut microbiota varied by indigenous microbiota of tested subject(10).
The combined study of a low-calorie diet and Ephera, in 125 otherwise healthy obese women, showed effectively in reducing BMI. RMR changes not compensated for by the herbal medicines tried.
Resting metabolic rate (RMR) change seemed to be affected by constitution and body composition rather than by medicine(11). The Dongeui University study of composition GGEx18( Laminaria japonica, Rheum palmatum, and Ephedra sinica) in high fat diet-induced obese mice suggested that GGEx18 improves obesity through skeletal muscle AMPK and AMPK-stimulated expression of PPARα and its target enzymes for fatty acid oxidation, through inhibited lipid accumulation, and similar activation of genes(12).
Please note that due to its adverse reactions of palpitations, stress, headache and insomnia and stroke, heart attacks, cardiac arrhythmias, seizures, and psychotic effect, the FDA banned the product on 2004, the Dutch Inspectorate for Health Care and the Ministry of Health in Canada have recently requested a market recall of some ephedrine-containing herbal products in response to above adverse reactions. In the Netherlands, the status of Ephedra-containing products is currently reconsidered(13)]
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Home page http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.
References
(1) Rising Burden of Obesity in Asia by Ambady Ramachandran and Chamukuttan Snehalatha(Journey of Obesity)
(2) Obesity - Situation and trends(WHO)
(3) Influence of a combination of herbs on appetite suppression and weight loss in rats by Talpur NA1, Echard BW, Manohar V, Preuss HG.(PubMed)
(4) [Hepatotoxicity induced by herbs and medicines used to induce weight loss].[Article in Spanish]by Herrera S1, Bruguera M.(PubMed)
(5) A case report of adult lead toxicity following use of Ayurvedic herbal medication by Breeher L1, Gerr F, Fuortes L.(PubMed)
(6) [Chronic lead intoxication associated with Ayurvedic medication].[Article in Dutch] by Kanen BL1, Perenboom RM.(PubMed)
(7) Potential toxicity of caffeine when used as a dietary supplement for weight loss by Pendleton M1, Brown S, Thomas C, Odle B.(PubMed)
(8) Multinutrient supplement containing ephedra and caffeine causes weight loss and improves metabolic risk factors in obese women: a randomized controlled trial by Hackman RM1, Havel PJ, Schwartz HJ, Rutledge JC, Watnik MR, Noceti EM, Stohs SJ, Stern JS, Keen CL.(PubMed)
(9) Ma Huang(Popular Chinese herbs)
(10) Prameha in Ayurveda: correlation with obesity, metabolic syndrome, and diabetes mellitus. Part 2--management of Prameha by Sharma H1, Chandola HM.(PubMed)
(11) Effect of herbal Ephedra sinica and Evodia rutaecarpa on body composition and resting metabolic rate: a randomized, double-blind clinical trial in Korean premenopausal women by Kim HJ1, Park JM, Kim JA, Ko BP(PubMed)
(12) The herbal composition GGEx18 from Laminaria japonica, Rheum palmatum, and Ephedra sinica reduces obesity via skeletal muscle AMPK and PPARα by Shin SS1, Park D, Lee HY, Hong Y, Choi J, Oh J, Lee H, Lee HR, Kim MR, Shen ZB, Cui HH, Yoon M.(PubMed)
(13) [Ephedrine and ephedra in weight loss products and other preparations].[Article in Dutch] by van der Hooft CS1, Stricker BH.(PubMed)
(14) Ginseng, Asian (Panax ginseng) and Ginseng, North America(Popular Chinese Herbs)
(15) Influence of Panax ginseng on obesity and gut microbiota in obese middle-aged Korean women by Song MY1, Kim BS2, Kim H(PubMed)
(16) Lipid metabolic effect of Korean red ginseng extract in mice fed on a high-fat diet by Song YB1, An YR, Kim SJ, Park HW, Jung JW, Kyung JS, Hwang SY, Kim YS.(PubMed)
(17) Popular #Herbs - #Ginger (Zingiber officinale)(Popular Chinese herbs)
(18) A systematic review of the efficacy and safety of herbal medicines used in the treatment of obesity by Hasani-Ranjbar S1, Nayebi N, Larijani B, Abdollahi M.(PubMed)
(19) Eight weeks of supplementation with a multi-ingredient weight lossproduct enhances body composition, reduces hip and waist girth, and increases energy levels in overweight men and women by Lopez HL1, Ziegenfuss TN, Hofheins JE, Habowski SM, Arent SM, Weir JP, Ferrando AA.(PubMed)
(20) Comparative evaluation of the efficacy of ginger and orlistat on obesity management, pancreatic lipase and liver peroxisomal catalase enzyme in male albino rats by Mahmoud RH1, Elnour WA.(PubMed)
(21) The use of a Cissus quadrangularis formulation in the management of weight loss and metabolic syndrome by Oben J1, Kuate D, Agbor G, Momo C, Talla X.(PubMed)
(22) The use of a Cissus quadrangularis/Irvingia gabonensis combination in the management of weight loss: a double-blind placebo-controlled study. by Oben JE1, Ngondi JL, Momo CN, Agbor GA, Sobgui CS.(PubMed)
(23) The effect of Cissus quadrangularis (CQR-300) and a Cissusformulation (CORE) on obesity and obesity-induced oxidative stress by Oben JE1, Enyegue DM, Fomekong GI, Soukontoua YB, Agbor GA.(PubMed)
(24) An observational study and quantification of the actives in a supplement with Sambucus nigra and Asparagus officinalis used for weight reduction by Chrubasik C1, Maier T, Dawid C, Torda T, Schieber A, Hofmann T, Chrubasik S.(PubMed)
(25) A systematic review of the efficacy and safety of herbal medicines used in the treatment of obesity by Hasani-Ranjbar S1, Nayebi N, Larijani B, Abdollahi M(PubMed)
(26) #Healthy #Foods - Vegetables - Asparagus (Asparagus officinalis)(health tips for better living and living health)
(27) An observational study and quantification of the actives in a supplement with Sambucus nigra and Asparagus officinalis used for weight reduction by Chrubasik C1, Maier T, Dawid C, Torda T, Schieber A, Hofmann T, Chrubasik S.(PubMed)
(28) Efficacy of 12 weeks supplementation of a botanical extract-based weight loss formula on body weight, body composition and blood chemistry in healthy, overweight subjects--a randomised double-blind placebo-controlled clinical trial by Opala T1, Rzymski P, Pischel I, Wilczak M, Wozniak J.(PubMed)
(29) A systematic review of the efficacy and safety of herbal medicines used in the treatment of obesity by Hasani-Ranjbar S1, Nayebi N, Larijani B, Abdollahi M.(PubMed)
Ginger, May Be A Natural Alternative for Testosterone Hormone Therapy with No Side Effects, According to Studies
Scientists may have a pungent spice which processes a potential to increased levels of testosterone deficiency, particularly in the elderly with no side effects according to studies.
Testosterone is a steroid hormone found in humans made mostly from the testicles in men and a small amount in women's ovaries.
According to epidemiological studies, treatment for hypogonadism is on the rise, particularly in the population due to natural reduced production of levels of testosterone other than normal aging.
Testosterone production starts to produce significantly during puberty and dip after age 30.
In males, the early onset of reduced production of levels of testosterone is associated with a highly prevalent burden of comorbid medical conditions and polypharmacy complicates compared to those of normal aging,
Also, low levels of testosterone in the males are associated with the early onset of metabolic syndrome in the induction of cardiovascular disease and type 2 diabetes.
Conventional medicine used for the treatment in this population is found to be a unique challenge to clinicians.
Apart from normal aging, low levels of testosterone are found to induce symptoms of decreased sex drive, low energy, weight gain, the risk of depression, and moodiness, loss of hair and thinner bones.
If you are experiencing some of the above symptoms, you may have low levels of testosterone. Please make sure you check with your doctor to rule out the possibility.
Dr. Giagulli VA, in examining the complications of testosterone in men wrote, "Testosterone deficiency syndrome (TDS) induces several negative effects that generally involve different organs such as testis, bone, skeletal muscle, and heart, leading to reduction in testis function, causing osteoporosis, strongly reducing muscle mass, decreasing exercise capacity and strength and facilitating heart failure".
And, " Approximately 25% of patients affected by chronic heart failure (CHF) is characterized by plasma Testosterone (T) levels below normal ranges also related to disease progression".
These results clearly suggested apart from normal aging, males with testosterone deficiency are associated with the complications of many ailments.
Ginger (Zingiber officinale) or ginger root, the second superfood used for thousands of years by mankind, is the genus Zingiber, belonging to the family Zingiberaceae, native to Tamil.
The root has been used in traditional and Chinese medicine to treat dyspepsia, gastroparesis, constipation, edema, difficult urination, colic, etc.
Scientists on finding a natural compound which processes a function in enhancing and protecting primary sex hormone in males examined the effects of ginger activity in enhancing testosterone production in males.
By searching the PubMed, Scopus, and Web of Science databases for English language articles (full texts or abstracts) from November 1991 through August 2018 using the keywords "ginger" and "Zingiber officinale" versus "testosterone" linking the effects of ginger on testosterone researchers found that ginger supplementation, particularly in oxidative stress conditions, enhances testosterone production in males.
The mechanisms by which this occurs mainly by enhancing luteinizing hormone (LH) production in stimulating the Leydig cell production of testosterone, increasing the level of cholesterol in synthesizing male sex steroid, testosterone (T), by reducing oxidative stress and lipid peroxidation in the testes.
Furthermore, application of ginger also inhibited the expression of free radical by promoting the activity of the antioxidant enzymes.
Ginger also normalized the blood glucose by increasing blood flow to the testes.
Moreover, ginger improved production of testosterone by increasing testicular weight and recycling testosterone receptors.
The finding strongly supports the use of ginger in the enhanced testosterone production for treatment of diseases associated with the testosterone deficiency.
In order to reveal more information about ginger in the production of testosterone by examing the
ginger effects on multiple animal models, including 60adult male Sprague Dawley rats divided into * Group A served as normal control,
* Group B received 0.3% lead acetate in drinking water,
*Group C and group D received supplementary 0.5 and 1 gm/Kg body weight of ginger respectively along with lead acetate in drinking water.
During the experiments, co-administration with different doses of ginger showed a significant rise in the testosterone levels in of teste, compared to the lead-treated group.
Interestingly, ginger application at different doses showed no significant change of LH levels, compared to the rise in the previous ginger treatment,
These results strongly suggested there must other compounds from ginger that exhibits the increased levels of LH that is not mentioned in both studies.
Taken altogether, ginger may be considered a functional remedy for the prevention and combined with primary medicine for the treatment for diseases associated with testosterone deficiency.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma ISSN 0975-6299.
Sources
(1) Ginger and Testosterone by Banihani SA. (PubMed)
(2) Protective role of ginger on lead induced derangement in plasma testosterone and luteinizing hormone levels of male Sprague Dawley rats by Riaz F1, Khan UA, Ayub M, Shaukat S.(PubMed)
(3) Testosterone deficiency in male: a risk factor for heart failure by Giagulli VA1, Guastamacchia E, De Pergola G, Iacoviello M, Triggiani V.(PubMed)
Testosterone is a steroid hormone found in humans made mostly from the testicles in men and a small amount in women's ovaries.
According to epidemiological studies, treatment for hypogonadism is on the rise, particularly in the population due to natural reduced production of levels of testosterone other than normal aging.
Testosterone production starts to produce significantly during puberty and dip after age 30.
In males, the early onset of reduced production of levels of testosterone is associated with a highly prevalent burden of comorbid medical conditions and polypharmacy complicates compared to those of normal aging,
Also, low levels of testosterone in the males are associated with the early onset of metabolic syndrome in the induction of cardiovascular disease and type 2 diabetes.
Conventional medicine used for the treatment in this population is found to be a unique challenge to clinicians.
Apart from normal aging, low levels of testosterone are found to induce symptoms of decreased sex drive, low energy, weight gain, the risk of depression, and moodiness, loss of hair and thinner bones.
If you are experiencing some of the above symptoms, you may have low levels of testosterone. Please make sure you check with your doctor to rule out the possibility.
Dr. Giagulli VA, in examining the complications of testosterone in men wrote, "Testosterone deficiency syndrome (TDS) induces several negative effects that generally involve different organs such as testis, bone, skeletal muscle, and heart, leading to reduction in testis function, causing osteoporosis, strongly reducing muscle mass, decreasing exercise capacity and strength and facilitating heart failure".
And, " Approximately 25% of patients affected by chronic heart failure (CHF) is characterized by plasma Testosterone (T) levels below normal ranges also related to disease progression".
These results clearly suggested apart from normal aging, males with testosterone deficiency are associated with the complications of many ailments.
Ginger (Zingiber officinale) or ginger root, the second superfood used for thousands of years by mankind, is the genus Zingiber, belonging to the family Zingiberaceae, native to Tamil.
The root has been used in traditional and Chinese medicine to treat dyspepsia, gastroparesis, constipation, edema, difficult urination, colic, etc.
Scientists on finding a natural compound which processes a function in enhancing and protecting primary sex hormone in males examined the effects of ginger activity in enhancing testosterone production in males.
By searching the PubMed, Scopus, and Web of Science databases for English language articles (full texts or abstracts) from November 1991 through August 2018 using the keywords "ginger" and "Zingiber officinale" versus "testosterone" linking the effects of ginger on testosterone researchers found that ginger supplementation, particularly in oxidative stress conditions, enhances testosterone production in males.
The mechanisms by which this occurs mainly by enhancing luteinizing hormone (LH) production in stimulating the Leydig cell production of testosterone, increasing the level of cholesterol in synthesizing male sex steroid, testosterone (T), by reducing oxidative stress and lipid peroxidation in the testes.
Furthermore, application of ginger also inhibited the expression of free radical by promoting the activity of the antioxidant enzymes.
Ginger also normalized the blood glucose by increasing blood flow to the testes.
Moreover, ginger improved production of testosterone by increasing testicular weight and recycling testosterone receptors.
The finding strongly supports the use of ginger in the enhanced testosterone production for treatment of diseases associated with the testosterone deficiency.
In order to reveal more information about ginger in the production of testosterone by examing the
ginger effects on multiple animal models, including 60adult male Sprague Dawley rats divided into * Group A served as normal control,
* Group B received 0.3% lead acetate in drinking water,
*Group C and group D received supplementary 0.5 and 1 gm/Kg body weight of ginger respectively along with lead acetate in drinking water.
During the experiments, co-administration with different doses of ginger showed a significant rise in the testosterone levels in of teste, compared to the lead-treated group.
Interestingly, ginger application at different doses showed no significant change of LH levels, compared to the rise in the previous ginger treatment,
These results strongly suggested there must other compounds from ginger that exhibits the increased levels of LH that is not mentioned in both studies.
Taken altogether, ginger may be considered a functional remedy for the prevention and combined with primary medicine for the treatment for diseases associated with testosterone deficiency.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma ISSN 0975-6299.
Sources
(1) Ginger and Testosterone by Banihani SA. (PubMed)
(2) Protective role of ginger on lead induced derangement in plasma testosterone and luteinizing hormone levels of male Sprague Dawley rats by Riaz F1, Khan UA, Ayub M, Shaukat S.(PubMed)
(3) Testosterone deficiency in male: a risk factor for heart failure by Giagulli VA1, Guastamacchia E, De Pergola G, Iacoviello M, Triggiani V.(PubMed)
Monday, March 2, 2020
Fennel In Ameliorated Risk, Progression and Treatment of Breast Cancer
Fennel may have a potential and therapeutic effect in reduced risk and treatment of breast cancer, some scientists suggested.
Breast cancer is a medical condition characterized by cell growth disorderly and uncontrollably in the breast tissue. At the later stage, cancerous cells may travel a distance away to infect other healthy tissue and organs.
Fennel (Foeniculum vulgare) is a plant species of genus, belongings to Apiaceae (Umbelliferae), native to the Mediterranean, used in traditional and herbal medicine as warming, carminative, antispasmodic, antidepressant agent and to stimulate the appetite, ease indigestion, soothe coughing, reduce intestinal spasms, to regulate the menstrual cycle and relieve PMS,...
Nutrients
1. Carbohydrates
2. Fiber
3. Protein
4. Thiamine (Vitamin B1)
5. Riboflavin (Vitamin B2)
6. Niacin (Vitamin B3)
7. Pantothenic acid (B5)
8. Vitamin B6
9. Folate (Vitamin B9)
10. Vitamin C
11. Calcium
12. Copper
13. Iron
14. Magnesium
15. Molybdenum
16. Phosphorus
17. Potassium
18. Zinc
19. Etc.
In the evaluation of the essential oil extracted from fennel activity in the human breast cancer cell line (MDA-Mb), researchers found that the application of fennel extract exerted a significant effect in inhibition of the expression of cancer cell lines at a dose of lower than 10 μg/mL with IC50.
According to the University of Malaya in investigation of the DNA protecting activity and inhibition of nicotine-induced cancer cell migration of 9 spices, fennel exerted a potential effect in protection of the DNA integrity and inhibition of nicotine-induced cancer cell migration against Murine fibroblasts (3T3-L1) and human breast cancer (MCF-7) cells pre-treated with spice extracts and then exposed to H₂O₂ and nicotine.
Additional analysis suggested that the result of inhibition was attributed to fennel antioxidants of phenols and flavonoids in ameliorated H2O2 in initiated chain activity in the induction of cytotoxicity in altered DNA of the experiment cell line.
Some researchers suggested that overproduction of hydrogen peroxide may serve as a prodrug in the presence of transition metal ions, in induced production of highly reactive hydroxyl radicals to initiated DNA damage in precipitated apoptosis.
In other words, the application of highly oxidative hydrogen peroxide in the breast cancer cell line may cause a significant cytotoxic effect in cancer cell death.
These results demonstrated the correlation of increase of apoptosis with the rise in the generation of reactive oxygen species in cancer cells.
Due to this potential activity, some researchers suggested that hydrogen peroxide overproduced in tumor cells can serve as a prodrug for the treatment of cancer.
On the other hand, the application of H2O2 in the healthy cells may induce DNA damage in the initiation of cancer cell development.
Furthermore, fennel scored a statistically significant DNA protecting activity compared to other spices, such as at ginger with 50 μg/ml in reduced 68% of DNA damage in 3T3-L1 cells.
However, Fennel exerted a lesser effect in inhibited cancer MCF-7 cells with nicotine-induced cell migration compared to other spices such as pepper, long pepper, and ginger.
The above differentiation was supported by the joint study lead by the Avicenna Tajik State Medical University, in the evaluation of the antioxidant effect of essential oil of fennel (Foeniculum vulgare) against MCF-7 (human breast adenocarcinoma).
According to the result from Gas chromatographic-mass spectrometric analysis, fennel displayed a moderated antioxidant in precipitated cytotoxic activity against MCF-7 (human breast adenocarcinoma) with IC50 values between 30-210 mg L-1 in compared to cytotoxic reference compounds.
In fact, the efficacy of fennel essential oil in inhibited breast cancer proliferation and migration was attributed to the presence of lipophilic secondary metabolites and anise aldehyde, which have potential in elevated the interference with molecular targets in cells by fennel antioxidant compounds such as anethole.
Taken together, fennel and its bioactive compound may be considered as functional food in reduced risk, progression, and treatment of breast cancer. However, intake of fennel supplements should be taken with extreme care in prevented liver acute toxicity.
For More information about yoga lessons tailor to a complete well being for women, please visit: YOGA FOR WOMEN
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Home page http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrients, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.
Sources
(1) Analysis and evaluation of the antimicrobial and anticancer activities of the essential oil isolated from Foeniculum vulgare from Hamedan, Iran by Akhbari M1, Kord R1, Jafari Nodooshan S2, Hamedi S3.(PubMed)
(2) Cytotoxicity of the Essential Oil of Fennel (Foeniculum vulgare) from Tajikistan by Sharopov F1,2, Valiev A3, Satyal P4, Gulmurodov I5, Yusufi S6, Setzer WN7, Wink M8.(PubMed)
(3) Dietary spices protect against hydrogen peroxide-induced DNA damage and inhibit nicotine-induced cancer cell migration by Jayakumar R1, Kanthimathi MS.(PubMed)
Breast cancer is a medical condition characterized by cell growth disorderly and uncontrollably in the breast tissue. At the later stage, cancerous cells may travel a distance away to infect other healthy tissue and organs.
Fennel (Foeniculum vulgare) is a plant species of genus, belongings to Apiaceae (Umbelliferae), native to the Mediterranean, used in traditional and herbal medicine as warming, carminative, antispasmodic, antidepressant agent and to stimulate the appetite, ease indigestion, soothe coughing, reduce intestinal spasms, to regulate the menstrual cycle and relieve PMS,...
Nutrients
1. Carbohydrates
2. Fiber
3. Protein
4. Thiamine (Vitamin B1)
5. Riboflavin (Vitamin B2)
6. Niacin (Vitamin B3)
7. Pantothenic acid (B5)
8. Vitamin B6
9. Folate (Vitamin B9)
10. Vitamin C
11. Calcium
12. Copper
13. Iron
14. Magnesium
15. Molybdenum
16. Phosphorus
17. Potassium
18. Zinc
19. Etc.
In the evaluation of the essential oil extracted from fennel activity in the human breast cancer cell line (MDA-Mb), researchers found that the application of fennel extract exerted a significant effect in inhibition of the expression of cancer cell lines at a dose of lower than 10 μg/mL with IC50.
According to the University of Malaya in investigation of the DNA protecting activity and inhibition of nicotine-induced cancer cell migration of 9 spices, fennel exerted a potential effect in protection of the DNA integrity and inhibition of nicotine-induced cancer cell migration against Murine fibroblasts (3T3-L1) and human breast cancer (MCF-7) cells pre-treated with spice extracts and then exposed to H₂O₂ and nicotine.
Additional analysis suggested that the result of inhibition was attributed to fennel antioxidants of phenols and flavonoids in ameliorated H2O2 in initiated chain activity in the induction of cytotoxicity in altered DNA of the experiment cell line.
Some researchers suggested that overproduction of hydrogen peroxide may serve as a prodrug in the presence of transition metal ions, in induced production of highly reactive hydroxyl radicals to initiated DNA damage in precipitated apoptosis.
In other words, the application of highly oxidative hydrogen peroxide in the breast cancer cell line may cause a significant cytotoxic effect in cancer cell death.
These results demonstrated the correlation of increase of apoptosis with the rise in the generation of reactive oxygen species in cancer cells.
Due to this potential activity, some researchers suggested that hydrogen peroxide overproduced in tumor cells can serve as a prodrug for the treatment of cancer.
On the other hand, the application of H2O2 in the healthy cells may induce DNA damage in the initiation of cancer cell development.
Furthermore, fennel scored a statistically significant DNA protecting activity compared to other spices, such as at ginger with 50 μg/ml in reduced 68% of DNA damage in 3T3-L1 cells.
However, Fennel exerted a lesser effect in inhibited cancer MCF-7 cells with nicotine-induced cell migration compared to other spices such as pepper, long pepper, and ginger.
The above differentiation was supported by the joint study lead by the Avicenna Tajik State Medical University, in the evaluation of the antioxidant effect of essential oil of fennel (Foeniculum vulgare) against MCF-7 (human breast adenocarcinoma).
According to the result from Gas chromatographic-mass spectrometric analysis, fennel displayed a moderated antioxidant in precipitated cytotoxic activity against MCF-7 (human breast adenocarcinoma) with IC50 values between 30-210 mg L-1 in compared to cytotoxic reference compounds.
In fact, the efficacy of fennel essential oil in inhibited breast cancer proliferation and migration was attributed to the presence of lipophilic secondary metabolites and anise aldehyde, which have potential in elevated the interference with molecular targets in cells by fennel antioxidant compounds such as anethole.
Taken together, fennel and its bioactive compound may be considered as functional food in reduced risk, progression, and treatment of breast cancer. However, intake of fennel supplements should be taken with extreme care in prevented liver acute toxicity.
For More information about yoga lessons tailor to a complete well being for women, please visit: YOGA FOR WOMEN
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Home page http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrients, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.
Sources
(1) Analysis and evaluation of the antimicrobial and anticancer activities of the essential oil isolated from Foeniculum vulgare from Hamedan, Iran by Akhbari M1, Kord R1, Jafari Nodooshan S2, Hamedi S3.(PubMed)
(2) Cytotoxicity of the Essential Oil of Fennel (Foeniculum vulgare) from Tajikistan by Sharopov F1,2, Valiev A3, Satyal P4, Gulmurodov I5, Yusufi S6, Setzer WN7, Wink M8.(PubMed)
(3) Dietary spices protect against hydrogen peroxide-induced DNA damage and inhibit nicotine-induced cancer cell migration by Jayakumar R1, Kanthimathi MS.(PubMed)
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