Cinnamon is a spice derived from the inner bark of tree, native to South East Asia, of over 300 species of the genus Cinnamomum, belonging to the familyLauraceae, use in herbal and traditional medicine as anti-fungal and bacteria level, to improve reproductive organ, prevent flatulence and intestinal cramping, and to treat indigestion, diarrhea, bad breath, headache, migraine, etc.
Topical use of essential oil extracted from cinnamon may be the next generation whole herb medicine for prevention and treatment of menstrual pain and heavy menstrual bleeding
According to the Eulji University, in the study compared the effect of aromatherapy massage and acetaminophen on menstrual pain in Korean high school girls. the cinnamon treatment group showed a significantly higher reduction of menstrual pain than in the acetaminophen group.
In a randomized, double-blind trial, out of 114, the group received Cinnamon (capsule containing 420 mg Cinnamon, TDS, n= 38) in 24 h significantly reduced the severity and duration of pain during menstruation and menstrual bleeding.
In primary dysmenorrhea, cinnamon expressed significantly over the reduction of pain, menstrual bleeding, nausea, and vomiting with primary dysmenorrhea without side effects.
Dr. Marzouk TM., the lead author at the Mansoura University said, " ... aromatherapy abdominal massage once daily for seven days prior to menstruation using the essential oils (cinnamon....) is effective in alleviating menstrual pain, its duration, and excessive menstrual bleeding...." and "Aromatherapy can be provided as a nonpharmacological pain relief measure and as a part of nursing care given to girls suffering from dysmenorrhea, or excessive menstrual bleeding".
Further study of the effect of cinnamon extract on symptoms of dysmenorrhea and contractility in some smooth muscles, Dr. Alotaibi M. suggested, cinnamon may be used to alleviate menstrual pain associated with dysmenorrhoea or prevent unwanted uterine activity in early pregnancy.
Indeed, Cinnamon may be the effective whole herb medicine used for the treatment of menstrual pain. Intake of cinnamon should be taken with care as toxicity is found in case of overdoses.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma ISSN 0975-6299.
Sources
(1) Aromatherapy massage on the abdomen for alleviating menstrual pain in high school girls: a preliminary controlled clinical study by Hur MH1, Lee MS, Seong KY, Lee MK.(PubMed)
(2) Comparative effect of cinnamon and Ibuprofen for treatment of primary dysmenorrhea: a randomized double-blind clinical trial by Jaafarpour M1, Hatefi M2, Khani A3, Khajavikhan J4.(PubMed)
(3) The effect of cinnamon on menstrual bleeding and systemic symptoms with primary dysmenorrhea by Jaafarpour M1, Hatefi M2, Najafi F3, Khajavikhan J4, Khani A3.(PubMed)
(4) The effect of aromatherapy abdominal massage on alleviating menstrual pain in nursing students: a prospective randomized cross-over study by Marzouk TM1, El-Nemer AM, Baraka HN.(PubMed)
(5) The effect of cinnamon extract on isolated rat uterine strips by Alotaibi M1.(PubMed)
Wednesday, August 5, 2020
Tuesday, August 4, 2020
Angelica Sinensis Destroys the Glioma Cells in Vitro and in Vivo
A glioma is a type of brain and spinal cord tumor characterized by the alternation of DNA of the glial cells.
Believe it or not, gliomas have been found accounting for 30 percent of all brain tumors and central nervous system tumors, and 80 percent of all malignant brain tumors.
Glioma can be classified into 3 types, including
* Astrocytomas are found in glial cells, star-shaped brain cells in the cerebrum called astrocytes. Most astrocytomas are localized.
* Ependymomas are cancers that grow in your brain or any part of the spine, including your neck and upper and lower back starting from the ependymal cells in the middle of your spinal cord and fluid-filled spaces in your brain.
* Oligodendrogliomas are cancers that begin on the oligodendrocytes of the brain or from a glial precursor cell.
Primary glioblastoma is considered the most aggressive cancer that begins within the brain. Cancer may arise de novo, meaning they begin as a Grade IV tumor with no evidence.
According to the statistic, the median survival time of primary glioblastoma is approximately 3 months without medical treatment. Glioblastomas represent about 15% of all primary brain tumors.
Due to the rapid growth of the tumor, patients diagnosed with primary glioblastoma experience brain swelling and increased brain pressure, leading to symptoms of nausea, vomiting, and severe headaches and localized symptoms depending on the location of the tumor.
Radiation and chemotherapy are the most common forms of treatment for patients with glioblastoma particularly, in a tumor that cannot be removed with surgery.
On finding a natural ingredient for the prevention and treatment of neurological diseases, scientists examined the inhibitory effects of Angelica polysaccharides (APs), bioactive constituents of Angelica on a glioma cell line.
Angelica or Dang Gui is a herb of Genus Angelica from the family Apiaceae, indigenous to China.
The herb has been used as a Queen herb in traditional Chinese medicine antispasmodic and vasodilatory agent, and to balance the hormones in women for a normal menstrual cycle and menstruation and strengthen heart, spleen, kidneys, and liver for both men and women, etc. In other words, it is used to treat gynecological ailments, fatigue, mild anemia, and high blood pressure. It has analgesic, anti-inflammatory, etc.
According to tested analysis both in vitro and in vivo models,
* APs exerted a significant inhibition of the growth and proliferation of U251 cells and induced their apoptosis.
* APs effectively reduced the expression of several cell cycle regulators such as cyclins D1, B, and E in the induction of cell cycle division of the tested cell line.
* APs also inhibited the anti-apoptotic protein Bcl-2 and increased the expression of pro-apoptotic proteins Bax and cleaved-caspase-3.
* Most importantly, APs inhibited the transforming growth factor (TGF)-β signaling pathway and stimulated the expression of E-cadherin, associated with the inhibition of cell growth.
Based on the results, researchers suggest, " the results indicate that APs attenuate the tumorigenicity of glioma cells and promote their apoptosis by suppressing the TGF-β signaling pathway".
Taken altogether, Dandelion may be considered a neuroprotective remedy, pending to the confirmation of the larger sample size and multicenter human study.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You. How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Angelica polysaccharides inhibit the growth and promote the apoptosis of U251 glioma cells in vitro and in vivo by Zhang WF1, Yang Y1, Li X1, Xu DY1, Yan YL1, Gao Q1, Jia AL1, Duan MH. (PubMed)
Believe it or not, gliomas have been found accounting for 30 percent of all brain tumors and central nervous system tumors, and 80 percent of all malignant brain tumors.
Glioma can be classified into 3 types, including
* Astrocytomas are found in glial cells, star-shaped brain cells in the cerebrum called astrocytes. Most astrocytomas are localized.
* Ependymomas are cancers that grow in your brain or any part of the spine, including your neck and upper and lower back starting from the ependymal cells in the middle of your spinal cord and fluid-filled spaces in your brain.
* Oligodendrogliomas are cancers that begin on the oligodendrocytes of the brain or from a glial precursor cell.
Primary glioblastoma is considered the most aggressive cancer that begins within the brain. Cancer may arise de novo, meaning they begin as a Grade IV tumor with no evidence.
According to the statistic, the median survival time of primary glioblastoma is approximately 3 months without medical treatment. Glioblastomas represent about 15% of all primary brain tumors.
Due to the rapid growth of the tumor, patients diagnosed with primary glioblastoma experience brain swelling and increased brain pressure, leading to symptoms of nausea, vomiting, and severe headaches and localized symptoms depending on the location of the tumor.
Radiation and chemotherapy are the most common forms of treatment for patients with glioblastoma particularly, in a tumor that cannot be removed with surgery.
On finding a natural ingredient for the prevention and treatment of neurological diseases, scientists examined the inhibitory effects of Angelica polysaccharides (APs), bioactive constituents of Angelica on a glioma cell line.
Angelica or Dang Gui is a herb of Genus Angelica from the family Apiaceae, indigenous to China.
The herb has been used as a Queen herb in traditional Chinese medicine antispasmodic and vasodilatory agent, and to balance the hormones in women for a normal menstrual cycle and menstruation and strengthen heart, spleen, kidneys, and liver for both men and women, etc. In other words, it is used to treat gynecological ailments, fatigue, mild anemia, and high blood pressure. It has analgesic, anti-inflammatory, etc.
According to tested analysis both in vitro and in vivo models,
* APs exerted a significant inhibition of the growth and proliferation of U251 cells and induced their apoptosis.
* APs effectively reduced the expression of several cell cycle regulators such as cyclins D1, B, and E in the induction of cell cycle division of the tested cell line.
* APs also inhibited the anti-apoptotic protein Bcl-2 and increased the expression of pro-apoptotic proteins Bax and cleaved-caspase-3.
* Most importantly, APs inhibited the transforming growth factor (TGF)-β signaling pathway and stimulated the expression of E-cadherin, associated with the inhibition of cell growth.
Based on the results, researchers suggest, " the results indicate that APs attenuate the tumorigenicity of glioma cells and promote their apoptosis by suppressing the TGF-β signaling pathway".
Taken altogether, Dandelion may be considered a neuroprotective remedy, pending to the confirmation of the larger sample size and multicenter human study.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You. How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Angelica polysaccharides inhibit the growth and promote the apoptosis of U251 glioma cells in vitro and in vivo by Zhang WF1, Yang Y1, Li X1, Xu DY1, Yan YL1, Gao Q1, Jia AL1, Duan MH. (PubMed)
Monday, August 3, 2020
Fennel, The Potent Neurons Protective and Memory Enhancing Functional Food
Intake of fennel daily and regularly may have a profound and positive effect in enhancing memory, some scientists suggested.
The human brain consists of billions of neurons, some of them were given a special function in storing the event from the past.
In other words, there is a faculty in the human brain in which the mind stores and remembers information.
There are 2 types of memory. The short-term memory (STM) is a temporary storage system that processes the working memory, reacted by taking into information that already was happened in the past.
Long-term memories are information collected by the brain that can last for just a few days, or years. Some long-term memories are more important than others.
Memory loss occurs often in the aging population. It is a normal degeneration, however, we can’t take action to slow it down a little.
Some researchers suggested that change of lifestyle, such as meditation and eating habits such as reduced intake of red meat which has been found to associate with lipid peroxidation can improve or slow down the risk of memory loss.
Dr. Xian Jiang, the lead author in the evaluation of the consumption of fruit and vegetables in the risk of cognitive impairment and dementia, wrote, "The meta-analysis showed that increased consumption of fruit and vegetables was associated with a significant reduction in the risk of cognitive impairment and dementia (the leading cause of memory loss)".
Risks of cognitive impairment and dementia-inducing memory loss were reduced by approximately 13% for an increment of 100 g per day of fruit and vegetable consumption.
A study that examines the fennel enhancing memory activity in an orogastric tube suggested that administration at doses of 50, 100, and 200 mg/kg body weight, fennel displays a significant effect in enhancing short and long-term memory.
Scientists at the research center, after taking into account all factors, recommended that adding a portion of fennel in the daily diet may improve memory in all aspects.
Fennel (Foeniculum vulgare) is a plant species of the genus, belongings to Apiaceae (Umbelliferae), native to the Mediterranean.
The herbal medicine has been used in traditional and herbal medicine, like warming, carminative, antispasmodic, antidepressant agent and to stimulate the appetite, ease indigestion, soothe coughing, reduce intestinal spasms, to regulate the menstrual cycle and relieve PMS,...
According to the observation of urinary levels of vanillylmandelic acid (VMA), daily administration of F. Vulgare extract (50, 100 and 200 mg/kg body weight) 1 h prior to the induction of stress, exerted a significantly altered the stress in reducing central nervous system in the expression of stress hormone production from 395.79 to 347.12, 311.21 and 258.86 μg/kg, receptively.
In comparison to ascorbic acid, fennel extracts treated groups also exhibited potent antioxidant effect by inhibiting lipid peroxidation in both tested rats liver and brain homogenates to a greater extent.
These results suggested that fennel extract may also improve brain function by reduced oxidative stress and lipid peroxidation in the induction of neuron cells cytotoxicity and apoptosis in facilitating plagues accumulation in the neurons, the process has long been found to decrease long-term memory recalled.
In the same period, memory deficits induced by scopolamine (1mg/kg, i.p.) in rats was significantly reversed by F. Vulgare dose-dependently.
Dr. A. E. Bawazirand, the lead author of the research paper said, "F. vulgare may be useful in the management of stress and stress-related disorders on account of its multiple actions such as anti-stress, memory-enhancing and antioxidant effects".
Further analysis of the enhanced memory and intelligence of F. vulgaris, an ayurvedic Rasayana (mixture) served to children as part of their food in Indian traditional medicine, scientists found that ingestion of whole plant extract at doses of 50, 100 and 200 mg/kg exhibits a strong memory-enhancing effect against scopolamine-induced amnesic rats.
Observed by conditioned avoidance response (CAR) technique, group treated with fennel extract of rats through gradually increased administration up to 95% over 7 to 12 days demonstrated a significant increase of percent avoidance due to information feedback from previous experience, compared to control group.
Additionally, fennel extracts showed strong linearly and independently in memory recalled from tested rats.
As Animals received 200 mg/kg body weight of the extract took ten days, while groups treated with 100 and 50 mg/kg doses of the extract required eleven and twelve days, respectively, to reach the point of acquisition.
Importantly, during the period of the experiment, treated rats demonstrated significantly less amnesia, a partial or total loss of memory induced by scopolamine in comparison to the nontreatment group.
Continuously, fennel treatment also produced better retention and recovery of memory deficits in a dose-dependent manner than the vehicle-treated animals.
Dr. Shamkant B. Badgujar, the lead scientist said, "Recovery from scopolamine-induced amnesia in the extract-treated groups took 3–5 days when compared to normal (control) group which took over 6 days".
Some researchers suggested that the neuro memory enhancement of fennel extracts may be attributed by the effective influence as a sedative and the herbal protective effects in the maintenance of brain tissue through directly increase the total content of neurotransmitters in all the tested regions.
Finally, "Fennel is likely to be safe for use as a moderator and enhancer of the functions of the central nervous system by increasing the total content of neurotransmitters and also can be a protection against stress and stress-related diseases such as memory loss, because it contains high amounts of antioxidants", according to the study of "Foeniculum vulgare Mill: A Review of Its Botany, Phytochemistry, Pharmacology, Contemporary Application, and Toxicology" suggestion.
Taking together, Fennel whole plant and whole plant extracts may be considered as a function in improved memory in all aspects.
These results also reaffirmed the use of fennel as a brain enhancer product by traditional herbal medicine.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) The effect of aqueous extracts of Fennel (Foenicul umvulgare Mill) seeds on some neurotransmitters Content and histological structure changing of cerebellar cortexin the brain of male albino rats by A. E. Bawazirand, L. E. Bokhary(Journal of American Science)
(2) Foeniculum vulgare Mill (Umbelliferae) Attenuates Stress and Improves Memory in Wister Rats by S Koppula, H Kumar(Tropical Journal of Pharmaceutical Research)
(5) Foeniculum vulgare Mill: A Review of Its Botany, Phytochemistry, Pharmacology, Contemporary Application, and Toxicology by Shamkant B. Badgujar,* Vainav V. Patel, and Atmaram H. Bandivdekar(PubMed)
The human brain consists of billions of neurons, some of them were given a special function in storing the event from the past.
In other words, there is a faculty in the human brain in which the mind stores and remembers information.
There are 2 types of memory. The short-term memory (STM) is a temporary storage system that processes the working memory, reacted by taking into information that already was happened in the past.
Long-term memories are information collected by the brain that can last for just a few days, or years. Some long-term memories are more important than others.
Memory loss occurs often in the aging population. It is a normal degeneration, however, we can’t take action to slow it down a little.
Some researchers suggested that change of lifestyle, such as meditation and eating habits such as reduced intake of red meat which has been found to associate with lipid peroxidation can improve or slow down the risk of memory loss.
Dr. Xian Jiang, the lead author in the evaluation of the consumption of fruit and vegetables in the risk of cognitive impairment and dementia, wrote, "The meta-analysis showed that increased consumption of fruit and vegetables was associated with a significant reduction in the risk of cognitive impairment and dementia (the leading cause of memory loss)".
Risks of cognitive impairment and dementia-inducing memory loss were reduced by approximately 13% for an increment of 100 g per day of fruit and vegetable consumption.
A study that examines the fennel enhancing memory activity in an orogastric tube suggested that administration at doses of 50, 100, and 200 mg/kg body weight, fennel displays a significant effect in enhancing short and long-term memory.
Scientists at the research center, after taking into account all factors, recommended that adding a portion of fennel in the daily diet may improve memory in all aspects.
Fennel (Foeniculum vulgare) is a plant species of the genus, belongings to Apiaceae (Umbelliferae), native to the Mediterranean.
The herbal medicine has been used in traditional and herbal medicine, like warming, carminative, antispasmodic, antidepressant agent and to stimulate the appetite, ease indigestion, soothe coughing, reduce intestinal spasms, to regulate the menstrual cycle and relieve PMS,...
According to the observation of urinary levels of vanillylmandelic acid (VMA), daily administration of F. Vulgare extract (50, 100 and 200 mg/kg body weight) 1 h prior to the induction of stress, exerted a significantly altered the stress in reducing central nervous system in the expression of stress hormone production from 395.79 to 347.12, 311.21 and 258.86 μg/kg, receptively.
In comparison to ascorbic acid, fennel extracts treated groups also exhibited potent antioxidant effect by inhibiting lipid peroxidation in both tested rats liver and brain homogenates to a greater extent.
These results suggested that fennel extract may also improve brain function by reduced oxidative stress and lipid peroxidation in the induction of neuron cells cytotoxicity and apoptosis in facilitating plagues accumulation in the neurons, the process has long been found to decrease long-term memory recalled.
In the same period, memory deficits induced by scopolamine (1mg/kg, i.p.) in rats was significantly reversed by F. Vulgare dose-dependently.
Dr. A. E. Bawazirand, the lead author of the research paper said, "F. vulgare may be useful in the management of stress and stress-related disorders on account of its multiple actions such as anti-stress, memory-enhancing and antioxidant effects".
Further analysis of the enhanced memory and intelligence of F. vulgaris, an ayurvedic Rasayana (mixture) served to children as part of their food in Indian traditional medicine, scientists found that ingestion of whole plant extract at doses of 50, 100 and 200 mg/kg exhibits a strong memory-enhancing effect against scopolamine-induced amnesic rats.
Observed by conditioned avoidance response (CAR) technique, group treated with fennel extract of rats through gradually increased administration up to 95% over 7 to 12 days demonstrated a significant increase of percent avoidance due to information feedback from previous experience, compared to control group.
Additionally, fennel extracts showed strong linearly and independently in memory recalled from tested rats.
As Animals received 200 mg/kg body weight of the extract took ten days, while groups treated with 100 and 50 mg/kg doses of the extract required eleven and twelve days, respectively, to reach the point of acquisition.
Importantly, during the period of the experiment, treated rats demonstrated significantly less amnesia, a partial or total loss of memory induced by scopolamine in comparison to the nontreatment group.
Continuously, fennel treatment also produced better retention and recovery of memory deficits in a dose-dependent manner than the vehicle-treated animals.
Dr. Shamkant B. Badgujar, the lead scientist said, "Recovery from scopolamine-induced amnesia in the extract-treated groups took 3–5 days when compared to normal (control) group which took over 6 days".
Some researchers suggested that the neuro memory enhancement of fennel extracts may be attributed by the effective influence as a sedative and the herbal protective effects in the maintenance of brain tissue through directly increase the total content of neurotransmitters in all the tested regions.
Finally, "Fennel is likely to be safe for use as a moderator and enhancer of the functions of the central nervous system by increasing the total content of neurotransmitters and also can be a protection against stress and stress-related diseases such as memory loss, because it contains high amounts of antioxidants", according to the study of "Foeniculum vulgare Mill: A Review of Its Botany, Phytochemistry, Pharmacology, Contemporary Application, and Toxicology" suggestion.
Taking together, Fennel whole plant and whole plant extracts may be considered as a function in improved memory in all aspects.
These results also reaffirmed the use of fennel as a brain enhancer product by traditional herbal medicine.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) The effect of aqueous extracts of Fennel (Foenicul umvulgare Mill) seeds on some neurotransmitters Content and histological structure changing of cerebellar cortexin the brain of male albino rats by A. E. Bawazirand, L. E. Bokhary(Journal of American Science)
(2) Foeniculum vulgare Mill (Umbelliferae) Attenuates Stress and Improves Memory in Wister Rats by S Koppula, H Kumar(Tropical Journal of Pharmaceutical Research)
(5) Foeniculum vulgare Mill: A Review of Its Botany, Phytochemistry, Pharmacology, Contemporary Application, and Toxicology by Shamkant B. Badgujar,* Vainav V. Patel, and Atmaram H. Bandivdekar(PubMed)
Sunday, August 2, 2020
Herbal Bilberry Protects the Neurons Against Memory Impairment in Vivo
Memory impairment is a condition of partial or complete loss of memory, depending on the quality of the neuron that has been affected.
Memory impairment other than the physical impact is a progressive disease that can lead to permanent loss of memory due to the gradual loss of neurons in the brain.
The most common risk factors associated with memory loss in the general population are long-term use of certain medications, excessive alcohol drinking, smoking, drug abuse, depression, nutrient deficiency, stroke, and daily stress.
In elderly or aging-induced memory loss are associated with the deterioration of a region of the brain involved in the formation and retrieval of memories, the hippocampus, and the reduced hormones and protein that protect and repair brain cells and stimulate neural growth.
However, some researchers suggested the rise of memory impairment in the elderly probably is correlated to the promotion of the Western diet over the past few decades.
Dr. Scott E. Kanoski, the lead scientist in the review the risk cognitive impairment in the Western diet consumption wrote, "Intake of saturated fats and simple carbohydrates, two of the primary components of a modern Western diet, is linked with the development of obesity and Alzheimer's Disease".
And, "Western diet intake is associated with cognitive impairment, with a specific emphasis on learning and memory functions that are dependent on the integrity of the hippocampus".
The results clearly stated if you are a Western diet follower, you are at a higher risk of memory impairment compared to healthy diet individuals.
Bilberry is a species of low-growing shrubs in the genus Vaccinium, belonging to the family Ericaceae, native to Northern Europe.
The plant berry has been used as herbs in traditional medicine for the treatment of acute and chronic diarrhea, gastritis, gastric ulcer, and duodenal ulcer, enterocolitis, ulcerative colitis, anemia, cystitis, kidney disease, and psoriasis, diabetes, etc.
With an aim to find a potential ingredient for the treatment of memory impairment researchers investigated the effects of Vaccinium uliginosum L. (bilberry) on the learning and memory impairments induced by amyloid-β protein (AβP) 1-42.
The evaluation included selected ICR Swiss mice divided randomly into 4 groups: the control (Aβ40-1A), control with 5% bilberry group (Aβ40-1B), amyloid β protein 1-42 treated group (Aβ1-42A), and Aβ1-42 with 5% bilberry group (Aβ1-42B).
According to the tested assays, bilberry added groups showed to decrease the finding time of hidden platform, compared to those of escape latencies of AβP to that of Aβ40-1.
Furthermore, the bilberry added Aβ1-42B group also showed a significant (P<0.05) increase of probe crossing frequency compared to Aβ1-42A.
In the passive avoidance test, bilberry significantly (P<0.05) increased the time of staying in the lighted area compared to AD control.
These results suggested that bilberry improved memory and learning capability in chemically induced Alzheimer's disease in experimental animal models.
In the incidence of degenerative disorders including Alzheimer's disease (AD), rats consumed approximately 3.2 mg kg(-1)day (oral), of the anthocyanins significantly enhanced short-term memory, but not long-term memory in the inhibitory avoidance task.
Moreover, injection of approximately 3.2 mg kg(-1)day (oral), of the anthocyanins also induced an increase in the number of crossings in the first exposure to the open field.
However, in the comparison of the radial maze and elevated plus-maze, lyophilized berries (blueberry, bilberry) improved working memory in the radial maze, with significant differences observed during sessions 1-2 and 4, compared to no effects in the elevated plus-maze task.
The findings strongly indicated the positive effects of administration of lyophilized Vaccinium berries (blueberry, bilberry) and anthocyanin in the prevention of memory deficits related to AD.
Taken altogether, bilberry processed abundantly bioactive compound anthocyanin may be considered a functional remedy for the prevention and treatment of memory impairment, pending to the validation of larger sample size and multicenter human study.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
References
(1) Vaccinium uliginosum L. Improves Amyloid β Protein-Induced Learning and Memory Impairment in Alzheimer's Disease in Mice by Choi YH1, Kwon HS1, Shin SG1, Chung CK. (PubMed)
(2) Effect of lyophilised Vaccinium berries on memory, anxiety and locomotion in adult rats by Ramirez MR1, Izquierdo I, do Carmo Bassols Raseira M, Zuanazzi JA, Barros D, Henriques AT. (PubMed)
(3) Western Diet Consumption and Cognitive Impairment: Links to Hippocampal Dysfunction and Obesity by Scott E. Kanoski1 and Terry L. Davidson. (PMC)
Memory impairment other than the physical impact is a progressive disease that can lead to permanent loss of memory due to the gradual loss of neurons in the brain.
The most common risk factors associated with memory loss in the general population are long-term use of certain medications, excessive alcohol drinking, smoking, drug abuse, depression, nutrient deficiency, stroke, and daily stress.
In elderly or aging-induced memory loss are associated with the deterioration of a region of the brain involved in the formation and retrieval of memories, the hippocampus, and the reduced hormones and protein that protect and repair brain cells and stimulate neural growth.
However, some researchers suggested the rise of memory impairment in the elderly probably is correlated to the promotion of the Western diet over the past few decades.
Dr. Scott E. Kanoski, the lead scientist in the review the risk cognitive impairment in the Western diet consumption wrote, "Intake of saturated fats and simple carbohydrates, two of the primary components of a modern Western diet, is linked with the development of obesity and Alzheimer's Disease".
And, "Western diet intake is associated with cognitive impairment, with a specific emphasis on learning and memory functions that are dependent on the integrity of the hippocampus".
The results clearly stated if you are a Western diet follower, you are at a higher risk of memory impairment compared to healthy diet individuals.
Bilberry is a species of low-growing shrubs in the genus Vaccinium, belonging to the family Ericaceae, native to Northern Europe.
The plant berry has been used as herbs in traditional medicine for the treatment of acute and chronic diarrhea, gastritis, gastric ulcer, and duodenal ulcer, enterocolitis, ulcerative colitis, anemia, cystitis, kidney disease, and psoriasis, diabetes, etc.
With an aim to find a potential ingredient for the treatment of memory impairment researchers investigated the effects of Vaccinium uliginosum L. (bilberry) on the learning and memory impairments induced by amyloid-β protein (AβP) 1-42.
The evaluation included selected ICR Swiss mice divided randomly into 4 groups: the control (Aβ40-1A), control with 5% bilberry group (Aβ40-1B), amyloid β protein 1-42 treated group (Aβ1-42A), and Aβ1-42 with 5% bilberry group (Aβ1-42B).
According to the tested assays, bilberry added groups showed to decrease the finding time of hidden platform, compared to those of escape latencies of AβP to that of Aβ40-1.
Furthermore, the bilberry added Aβ1-42B group also showed a significant (P<0.05) increase of probe crossing frequency compared to Aβ1-42A.
In the passive avoidance test, bilberry significantly (P<0.05) increased the time of staying in the lighted area compared to AD control.
These results suggested that bilberry improved memory and learning capability in chemically induced Alzheimer's disease in experimental animal models.
In the incidence of degenerative disorders including Alzheimer's disease (AD), rats consumed approximately 3.2 mg kg(-1)day (oral), of the anthocyanins significantly enhanced short-term memory, but not long-term memory in the inhibitory avoidance task.
Moreover, injection of approximately 3.2 mg kg(-1)day (oral), of the anthocyanins also induced an increase in the number of crossings in the first exposure to the open field.
However, in the comparison of the radial maze and elevated plus-maze, lyophilized berries (blueberry, bilberry) improved working memory in the radial maze, with significant differences observed during sessions 1-2 and 4, compared to no effects in the elevated plus-maze task.
The findings strongly indicated the positive effects of administration of lyophilized Vaccinium berries (blueberry, bilberry) and anthocyanin in the prevention of memory deficits related to AD.
Taken altogether, bilberry processed abundantly bioactive compound anthocyanin may be considered a functional remedy for the prevention and treatment of memory impairment, pending to the validation of larger sample size and multicenter human study.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
References
(1) Vaccinium uliginosum L. Improves Amyloid β Protein-Induced Learning and Memory Impairment in Alzheimer's Disease in Mice by Choi YH1, Kwon HS1, Shin SG1, Chung CK. (PubMed)
(2) Effect of lyophilised Vaccinium berries on memory, anxiety and locomotion in adult rats by Ramirez MR1, Izquierdo I, do Carmo Bassols Raseira M, Zuanazzi JA, Barros D, Henriques AT. (PubMed)
(3) Western Diet Consumption and Cognitive Impairment: Links to Hippocampal Dysfunction and Obesity by Scott E. Kanoski1 and Terry L. Davidson. (PMC)
Saturday, August 1, 2020
Chaste Tree Berry, the Best Anti Inflammatory Whole Food
Chaste tree berry may process a strong anti-inflammatory effect in reduced symptoms of reddened, swollen, hot caused by an overreaction of immunity, a study suggested.
Inflammatory activity is an action of the immune system taken to protect the body against injury and infection.
Chaste tree berry is a species of Vitex agnus-castus, genus Vitex, belonging to the family Lamiaceae, native to the Mediterranean region, used in herbal medicine for thousands of years as an aphrodisiac herb and considered as Queen herb in treating menstrual problems and discomforts.
According to Kyung Hee University, casticin a major compound found from Vitex species at doses of 1, 2, and 10mg/kg casticin via an i.p. injection to C57BL/6 mice, expressed a significant effect in inhibition of the numbers of cells of neutrophils, macrophages, and lymphocytes through reduced levels of proinflammatory cytokines and chemokines, as shown in the bronchoalveolar lavage fluid (BALF), and lung histological analysis.
Furthermore, the tested compound also displayed a remarkably decreased the peribronchial thickening or bronchial wall thickening and perivascular inflammatory cells and the epithelium thickness in mice with lung inflammation, particular to chronic obstructive pulmonary disease (COPD).
In some newly found chemical compound isolated from Chaste tree berry, namely a phenylindene-type lignan, vitexdoin F (1), and three phenylnaphthalene-type lignans, vitexdoins G, H and I (2-4) in the testing of anti inflammatory activities, Compound 1 showed a significant inhibition on the nitric oxide (NO) production (IC50 4.17 μg/mL) in induced inflammation.
Other, in the evaluation of the anti-arthritic activity of the extract of V. negundo seeds (EVNS) using Freund's complete adjuvant (CFA) induced arthritis (AA) in rat model, oral administrated rats showed elevated anti-inflammatory activities through suppressed paw edema, decreased the arthritis score, spleen index, and reversed the weight loss.
In fact, the efficacy of extract of Chaste tree berry in reduced inflammation may be resulted of suppressed expression of the protein in regulated pro-inflammatory cytokines in various inflammatory pathways.
Taking together, phytochemical compounds found in Chaste tree berry may exhibit strong anti-inflammatory properties through ameliorated the protein involved the expression of proinflammatory
cytokines.
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Home page http://kylejnorton.blogspot.ca
Sources
(1) Casticin, an active compound isolated from Vitex Fructus, ameliorates the cigarette smoke-induced acute lung inflammatory response in a murine model by Lee H1, Jung KH2, Lee H3, Park S4, Choi W5, Bae H6(PubMed)
(2) Anti-inflammatory and anti-osteoporotic lignans from Vitex negundo seeds by Zheng CJ1, Zhang XW2, Han T1, Jiang YP1, Tang JY3, Brömme D4, Qin LP5.(PubMed)
Inflammatory activity is an action of the immune system taken to protect the body against injury and infection.
Chaste tree berry is a species of Vitex agnus-castus, genus Vitex, belonging to the family Lamiaceae, native to the Mediterranean region, used in herbal medicine for thousands of years as an aphrodisiac herb and considered as Queen herb in treating menstrual problems and discomforts.
According to Kyung Hee University, casticin a major compound found from Vitex species at doses of 1, 2, and 10mg/kg casticin via an i.p. injection to C57BL/6 mice, expressed a significant effect in inhibition of the numbers of cells of neutrophils, macrophages, and lymphocytes through reduced levels of proinflammatory cytokines and chemokines, as shown in the bronchoalveolar lavage fluid (BALF), and lung histological analysis.
Furthermore, the tested compound also displayed a remarkably decreased the peribronchial thickening or bronchial wall thickening and perivascular inflammatory cells and the epithelium thickness in mice with lung inflammation, particular to chronic obstructive pulmonary disease (COPD).
In some newly found chemical compound isolated from Chaste tree berry, namely a phenylindene-type lignan, vitexdoin F (1), and three phenylnaphthalene-type lignans, vitexdoins G, H and I (2-4) in the testing of anti inflammatory activities, Compound 1 showed a significant inhibition on the nitric oxide (NO) production (IC50 4.17 μg/mL) in induced inflammation.
Other, in the evaluation of the anti-arthritic activity of the extract of V. negundo seeds (EVNS) using Freund's complete adjuvant (CFA) induced arthritis (AA) in rat model, oral administrated rats showed elevated anti-inflammatory activities through suppressed paw edema, decreased the arthritis score, spleen index, and reversed the weight loss.
In fact, the efficacy of extract of Chaste tree berry in reduced inflammation may be resulted of suppressed expression of the protein in regulated pro-inflammatory cytokines in various inflammatory pathways.
Taking together, phytochemical compounds found in Chaste tree berry may exhibit strong anti-inflammatory properties through ameliorated the protein involved the expression of proinflammatory
cytokines.
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Home page http://kylejnorton.blogspot.ca
Sources
(1) Casticin, an active compound isolated from Vitex Fructus, ameliorates the cigarette smoke-induced acute lung inflammatory response in a murine model by Lee H1, Jung KH2, Lee H3, Park S4, Choi W5, Bae H6(PubMed)
(2) Anti-inflammatory and anti-osteoporotic lignans from Vitex negundo seeds by Zheng CJ1, Zhang XW2, Han T1, Jiang YP1, Tang JY3, Brömme D4, Qin LP5.(PubMed)
Friday, July 31, 2020
Herbal Angelica, A Promising Anti-Colorectal Cancer in Vivo
Colorectum including the large intestine and the rectum is the second part of the digestive system involved in the absorption of water from the small bowel contents and breaks down certain materials in the feces into substances of which some of them to be reabsorbed and reused by the body.
The colon also is known as the large bowel or large intestine, formed parts of the digestive system in our body.
The colon consists of four parts: descending colon, ascending colon, transverse colon, and sigmoid colon.
The main functions of the colon are to reabsorb fluids and process waste products from the body and prepare for its elimination.
Colorectal cancer is a medical condition caused by irregular cell growth in the tissue of the colon or rectum.
Most cases of colorectal cancer start in the cells on the surface of the inner lining in the colon and rectum, before penetrating into deeper layers to form a tumor through proliferation.
Colorectal cancer is a relatively very slow-growing cancer that progresses in a predictable way.
According to the statistics provided by the American Cancer Society, excluding skin cancers, colorectal cancer is the third most common cancer diagnosed in both men and women in the United States.
In 2019, approximately 101,420 new cases of colon cancer and 44,180 new cases of rectal cancer will be diagnosed in the US.
The 5-year survival rate of colorectal cancer diagnosed at the localized stage is 90%. Sadly, only 39% of patients are diagnosed at this early stage.
Most common types of colorectal cancer classified depending on the primary originated cells are
* Adenocarcinomas
Most bowel cancers are adenocarcinomas, originated in epithelium tissues, including the surface layer of skin, glands and their tissues that line the cavities and organs of the body.
* Squamous cell cancers
Squamous cells are the skin-like cells that make up the bowel lining together with the gland cells. Squamous cell cancers are rare with a risk of 25 per 100000 population.
On finding a natural ingredient for the prevention and treatment of cancers, scientists examined the chemopreventive effect of the supercritical extracts from Angelica sinensis (SFE-AS) on induced colorectal carcinoma in mice.
Angelica or Dang Qui is a herb of Genus Angelica from the family Apiaceae, indigenous to China.
The herb has been used as a Queen herb in traditional Chinese medicine antispasmodic and vasodilatory agent, and to balance the hormones in women for a normal menstrual cycle and menstruation and strengthen heart, spleen, kidneys, and liver for both men and women, etc. In other words, it is used to treat gynecological ailments, fatigue, mild anemia, and high blood pressure. It has analgesic, anti-inflammatory, etc.
According to the results of selected male colorectal carcinoma mice that were subcutaneously injected with a single dose of azoxymethane (AOM, 10 mg x kg(-1) body weight) then one week later, given 2% dextran sodium sulfate (DSS) in drinking water for 7 days to induce colorectal carcinoma, following by oral administration of supercritical extracts from Angelica sinensis at 15, 30, 60 mg x kg(-1) until the 17th week,* The Tumor-bearing quantity and tumor-bearing volume of the SFE-AS group were lower than that of the AOM/DSS model control group.
* The SFE-AS group also showed a significant reduction of oxidative stress in the AOM/DSS-induced mouse colorectal carcinoma model associated with inflammation.
In other words, the application of Angelica sinensis at 15, 30, 60 mg x kg(-1) and strong inhibitory activity against 2% dextran sodium sulfate (DSS) induced colorectal carcinoma,
Based on the evidence, researchers said, "SFE-AS showed an intervention effect in the incidence and development of AOM/DSS-induced mouse colorectal carcinoma associated with inflammation, and could be further used in chemo-preventive studies on human colorectal carcinoma".
Taken altogether, Herbal Angelica may be considered an anti colorectal cancer herbal remedy, pending to the confirmation of the larger sample size and multicenter human study.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You. How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) [Chemo-preventive effect of Angelica sinensis' supercritical extracts on AOM/DSS-induced mouse colorectal carcinoma associated with inflammation].[Article in Chinese] by An J, Li XN, Zhao BC, Wang Q, Lan Y, Wu Q. (PubMed)
The colon also is known as the large bowel or large intestine, formed parts of the digestive system in our body.
The colon consists of four parts: descending colon, ascending colon, transverse colon, and sigmoid colon.
The main functions of the colon are to reabsorb fluids and process waste products from the body and prepare for its elimination.
Colorectal cancer is a medical condition caused by irregular cell growth in the tissue of the colon or rectum.
Most cases of colorectal cancer start in the cells on the surface of the inner lining in the colon and rectum, before penetrating into deeper layers to form a tumor through proliferation.
Colorectal cancer is a relatively very slow-growing cancer that progresses in a predictable way.
According to the statistics provided by the American Cancer Society, excluding skin cancers, colorectal cancer is the third most common cancer diagnosed in both men and women in the United States.
In 2019, approximately 101,420 new cases of colon cancer and 44,180 new cases of rectal cancer will be diagnosed in the US.
The 5-year survival rate of colorectal cancer diagnosed at the localized stage is 90%. Sadly, only 39% of patients are diagnosed at this early stage.
Most common types of colorectal cancer classified depending on the primary originated cells are
* Adenocarcinomas
Most bowel cancers are adenocarcinomas, originated in epithelium tissues, including the surface layer of skin, glands and their tissues that line the cavities and organs of the body.
* Squamous cell cancers
Squamous cells are the skin-like cells that make up the bowel lining together with the gland cells. Squamous cell cancers are rare with a risk of 25 per 100000 population.
On finding a natural ingredient for the prevention and treatment of cancers, scientists examined the chemopreventive effect of the supercritical extracts from Angelica sinensis (SFE-AS) on induced colorectal carcinoma in mice.
Angelica or Dang Qui is a herb of Genus Angelica from the family Apiaceae, indigenous to China.
The herb has been used as a Queen herb in traditional Chinese medicine antispasmodic and vasodilatory agent, and to balance the hormones in women for a normal menstrual cycle and menstruation and strengthen heart, spleen, kidneys, and liver for both men and women, etc. In other words, it is used to treat gynecological ailments, fatigue, mild anemia, and high blood pressure. It has analgesic, anti-inflammatory, etc.
According to the results of selected male colorectal carcinoma mice that were subcutaneously injected with a single dose of azoxymethane (AOM, 10 mg x kg(-1) body weight) then one week later, given 2% dextran sodium sulfate (DSS) in drinking water for 7 days to induce colorectal carcinoma, following by oral administration of supercritical extracts from Angelica sinensis at 15, 30, 60 mg x kg(-1) until the 17th week,* The Tumor-bearing quantity and tumor-bearing volume of the SFE-AS group were lower than that of the AOM/DSS model control group.
* The SFE-AS group also showed a significant reduction of oxidative stress in the AOM/DSS-induced mouse colorectal carcinoma model associated with inflammation.
In other words, the application of Angelica sinensis at 15, 30, 60 mg x kg(-1) and strong inhibitory activity against 2% dextran sodium sulfate (DSS) induced colorectal carcinoma,
Based on the evidence, researchers said, "SFE-AS showed an intervention effect in the incidence and development of AOM/DSS-induced mouse colorectal carcinoma associated with inflammation, and could be further used in chemo-preventive studies on human colorectal carcinoma".
Taken altogether, Herbal Angelica may be considered an anti colorectal cancer herbal remedy, pending to the confirmation of the larger sample size and multicenter human study.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You. How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) [Chemo-preventive effect of Angelica sinensis' supercritical extracts on AOM/DSS-induced mouse colorectal carcinoma associated with inflammation].[Article in Chinese] by An J, Li XN, Zhao BC, Wang Q, Lan Y, Wu Q. (PubMed)
Thursday, July 30, 2020
Herbal Coltsfoot(Tussilago farfara), A Natural Neuro-Protective Remedy
Neuroprotection is a process to preserve the neuronal structure and/or function against the death or gradual death of neurons, including the use of medicines and herbs.
In other words, neuroprotection protects the neuronal integrity against the reduction in the rate of neuronal loss over time inducing neurological disease, including neurodegenerative disease.
Neurodegenerative disease is the class of condition associated with the progressive loss of neuron occurred mostly in older adults, including dementia. The most common dementia in the US is Alzheimer`s disease (AD).
Alzheimer's disease is an irreversible, progressive brain disorder caused by the slowly lost of neuron in the brain that affects the memory and thinking skills and, eventually, the ability to carry out the simplest tasks as the disease progress into advanced stage.
According to the statistic, dementia affects over 47.5 million people worldwide, approximately 58 percent are living within low and middle-income countries.
Believe it or not, 5.8 million Americans of all ages are living with Alzheimer's dementia in 2019 and two-thirds of people with Alzheimer's disease are women.
Conventionally, as of today, there is no cure for dementia. Treatment of dementia is focusing to improve dementia symptoms and slow down the progression of the disease.
Coltsfoot(Tussilago farfara) is a perennial herbaceous plant, genus Tussilago, belonging to the family Asteraceae, native to Europe and Asia. The herb has been used over thousands of years to treat asthma, various coughs, bronchial congestion, respiratory disorders, headaches and obstruction in the nasal passage, etc.
On finding a potential compound for the treatment of the neurological disorder, researchers examined the neuroprotective effect of Tussilagone (TSL) on LPS-induced neuronal cell death.
According to the tested assays, 4 sesquiterpenoids isolated from the TSL showed a significant effect against the production of nitric oxide, prostaglandin E2 and tumor necrosis factor-α in LPS-treated BV-2 cells.
In other words, the sesquiterpenoids inhibited the production of free radicals and proinflammatory expression associated with the BV-2 cells oxidative stress induced by LPS.
More precisely, the inhibition against the initiation of oxidative stress was attributed to the sesquiterpenoids activity in blocking the activation of the proinflammatory (NF-κB) pathway
Furthermore, the sesquiterpenoids also inhibited LPS-induced neuronal cell death in the co-culture system by inhibiting the expression of NF-κB pathway and scavenging of ROS.
Based on the findings, researchers said, "sesquiterpenoids from Tussilago farfara may have beneficial therapeutic potential for the treatment of neurodegenerative diseases through inhibition of microglial activation".
Taken altogether, coltsfoot may be considered a remedy for the treatment of neurological disease, pending to the confirmation of the larger sample size and multicenter human study.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You. How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) In vitro neuroprotective activity of sesquiterpenoids from the flower buds of Tussilago farfara by Lim HJ1, Dong GZ, Lee HJ, Ryu JH. (PubMed)
(2) Neuroprotection against 6-OHDA toxicity in PC12 cells and mice through the Nrf2 pathway by a sesquiterpenoid from Tussilago farfara by Lee J1, Song K1, Huh E2, Oh MS3, Kim YS. (PubMed)
In other words, neuroprotection protects the neuronal integrity against the reduction in the rate of neuronal loss over time inducing neurological disease, including neurodegenerative disease.
Neurodegenerative disease is the class of condition associated with the progressive loss of neuron occurred mostly in older adults, including dementia. The most common dementia in the US is Alzheimer`s disease (AD).
Alzheimer's disease is an irreversible, progressive brain disorder caused by the slowly lost of neuron in the brain that affects the memory and thinking skills and, eventually, the ability to carry out the simplest tasks as the disease progress into advanced stage.
According to the statistic, dementia affects over 47.5 million people worldwide, approximately 58 percent are living within low and middle-income countries.
Believe it or not, 5.8 million Americans of all ages are living with Alzheimer's dementia in 2019 and two-thirds of people with Alzheimer's disease are women.
Conventionally, as of today, there is no cure for dementia. Treatment of dementia is focusing to improve dementia symptoms and slow down the progression of the disease.
Coltsfoot(Tussilago farfara) is a perennial herbaceous plant, genus Tussilago, belonging to the family Asteraceae, native to Europe and Asia. The herb has been used over thousands of years to treat asthma, various coughs, bronchial congestion, respiratory disorders, headaches and obstruction in the nasal passage, etc.
On finding a potential compound for the treatment of the neurological disorder, researchers examined the neuroprotective effect of Tussilagone (TSL) on LPS-induced neuronal cell death.
According to the tested assays, 4 sesquiterpenoids isolated from the TSL showed a significant effect against the production of nitric oxide, prostaglandin E2 and tumor necrosis factor-α in LPS-treated BV-2 cells.
In other words, the sesquiterpenoids inhibited the production of free radicals and proinflammatory expression associated with the BV-2 cells oxidative stress induced by LPS.
More precisely, the inhibition against the initiation of oxidative stress was attributed to the sesquiterpenoids activity in blocking the activation of the proinflammatory (NF-κB) pathway
Furthermore, the sesquiterpenoids also inhibited LPS-induced neuronal cell death in the co-culture system by inhibiting the expression of NF-κB pathway and scavenging of ROS.
Based on the findings, researchers said, "sesquiterpenoids from Tussilago farfara may have beneficial therapeutic potential for the treatment of neurodegenerative diseases through inhibition of microglial activation".
Taken altogether, coltsfoot may be considered a remedy for the treatment of neurological disease, pending to the confirmation of the larger sample size and multicenter human study.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You. How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) In vitro neuroprotective activity of sesquiterpenoids from the flower buds of Tussilago farfara by Lim HJ1, Dong GZ, Lee HJ, Ryu JH. (PubMed)
(2) Neuroprotection against 6-OHDA toxicity in PC12 cells and mice through the Nrf2 pathway by a sesquiterpenoid from Tussilago farfara by Lee J1, Song K1, Huh E2, Oh MS3, Kim YS. (PubMed)
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