Monday, September 21, 2020
Bromelain Ameliorates Endometrial Pain
Endometriosis is a medical condition caused by the tissue of the endometrium that grows outside the uterus, leading to severe abnormal pain.
Most cases of endometriosis are found to involve the ovaries, fallopian tubes and the tissue lining the pelvis.
Some researchers suggested the cause of endometriosis is a result of a layer of endometriosis lining on the inside of the uterus is expelled, instead, some of the endometriosis tissues grow somewhere in the body in the last stage menstrual cycle (menstruation).
Endometriosis also reacts to hormone signals of the monthly menstrual cycle, by building up tissue, breaking it, and eliminating, according to the stage of the menstrual period. Since they grow in somewhere other than in the uterus when they break, the period blood has no way to exit, causing blood attaching to the organs or lining of the abdomen, resulting in scars or adhesion as well as weakening the normal function of organs.
According to statistics, endometriosis affects
a) About 20% of reproductive-age women with endometriosis present but without symptoms.
b) About 55% of women who have developed the new onset of severe menstrual cramps.
c) About 25% of women with sub-fertility (less fertile than a normal couple)
Endometriosis can vary in appearance. It may be clear or white, reddish, brown or blue-black, and cysts. The condition can be classified according to the stage of severity:
* Minimal stage:
The top surface, few in number. Commonly they are found in the inside wall of the uterus, ligaments, and ovary.
* Mild stage:
Deeper implants, greater numbers are presented. Commonly found in the same area as a minimal stage.
* Moderate stage:
Many implants, endometrial cysts present, affecting ovary function, causing scar tissues and adhesion is also present.
* Severe stage:
Intensive peritoneal implants, large endometriomas present, and dense adhesion.
Each woman experiences differently from endometriosis. Some women may have extensive endometrial tissues in their body but feel little or no pain, while other women may only be in the early stage of endometriosis but have excessive pain.
Bromelain, a proteolytic enzyme found in pineapples (Ananas comosus) has been used in traditional medicine as an inflammatory agent and to treat pains, strains, and muscle aches and pains and ease back pain and chronic joint pain, skin diseases, etc.
With an aim to find a potential ingredient for the treatment of endometriosis-associated pelvic pain, researchers evaluated the antioxidant activity of a preparation containing N-acetyl cysteine, alpha lipoic acid, and bromelain.
The multicenter, open-label, non-comparative clinical trial included a sample of 398 patients with a mean age of 34.6 ± 7.2 years with endometriosis-associated pelvic pain.
According to the results of a combination of N-acetyl cysteine, alpha-lipoic acid and bromelain treatment after 6 months, in comparison of 92.7% of the patients with pain intensity > 4 on the visual analogue scale (VAS) at the baseline, the percentage was decreased to 87.2% (p = 0.074) at 3 months of treatment.
Also compared to the baseline, the percentage decreased even more at 82.7% (p < 0.05) at the 6 months treatment.
More importantly, the use of medicine for pain relief also was also reduced upon the application of the combination, according to the results of the experiment.
Dr. Lete I, the lead scientist said at the final report, "Women with endometriosis who wish to become pregnant and are treated with a preparation containing N-acetyl cysteine, alpha lipoic acid and bromelain experienced a significant improvement in endometriosis-associated pelvic pain and required lower intake of rescue analgesics".
Taken altogether, bromelain used alone or combined with other remedies may be considered supplements for the prevention and treatment of endometrial pain, pending to the confirmation of the larger sample size and multicenter human study.
Intake of bromelain in the form of supplements should be taken with extreme care to prevent overdose acute liver toxicity.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(2) Effectiveness of an antioxidant preparation with N-acetyl cysteine, alpha lipoic acid and bromelain in the treatment of endometriosis-associated pelvic pain: LEAP study by Lete I1, Mendoza N2, de la Viuda E3, Carmona F. (PubMed)
Sunday, September 20, 2020
Bromelain Promotes Enzyme and Evokes Antibodies Against the Progression of Lung Cancer
Lung cancer is a chronic condition characterized by the irregular cell in the lung tissues caused by the alternation of cells DNA.
The lung is a vital organ of the human being, located near the backbone on either side of the heart with functions of inhaling oxygen from the air then transporting them to the bloodstream and exhaling carbon dioxide from the bloodstream.
According to the statistics, in the US, lung cancer is the leading cause of cancer deaths. In n 2007. lung caused the death of 158,683 Americans, including 88,329 men and 70,354 women i
There are several types of lung cancer including
1. Non-small cell lung cancer
Non-small cell lung cancer, the most common type of lung cancer grown and spread methodically and predictably, includes
* Squamous-cell carcinoma often found in an outer area of the lung.
*Large-cell carcinoma found in the center of the lung by an air tube.
* Adenocarcinoma found in any part of the lung.
2. Small cell lung cancer
Small cell lung cancer is an aggressive type of lung cancer. The cells of small cell cancer have been found to spread to distant parts of the body in a relatively early stage.
* Small cell carcinoma in which the cells are small, round and resemble oats.
* Mixed small cell/large cell carcinoma, the malignant tumor is found in combining components of small cell lung carcinoma with large cell lung carcinoma.
* Combined small cell carcinoma, the malignant tumor is found in combining of a component of small cell lung carcinoma with components of non-small cell lung carcinoma
Out of many risk factors associated with the onset of lung cancer, some researchers suggested smokers are at substantial risk of the disease.
Dr. Ozlü T the lead scientist wrote, "It is estimated that deaths attributable to tobacco use will rise to 10 million by 2025, and one-third of all adult deaths are expected to be related to cigarette smoking".
And, "Tobacco use has been reported to be the main cause of 90% of male and 79% of female lung cancers. 90% of deaths from lung cancer are estimated to be due to smoking. The risk of lung cancer development is 20-40 times higher in lifelong smokers compared to non-smokers".
The results strongly suggested that if you are a smoker, your risk of lung cancer developing is rocketing.
Bromelain, a proteolytic enzyme found in pineapples (Ananas comosus) has been used in traditional medicine as an inflammatory agent and to treat pains, strains, and muscle aches and pains and ease back pain and chronic joint pain, skin diseases, etc.
With an aim to find a natural ingredient against lung cancer, researchers examined the effects of the antitumor effect of fastuosain, a cysteine proteinase from Bromelia fastuosa on the intravenous model of lung colonization in C57Bl/6 mice.
According to the tested assays, fastuosain showed reduced expression of the marker of cancer progression (CD44) and decreased invasion by inhibiting cancer cell communication and inflammation in tumor cells.
Furthermore, fastuosain also induced cancer apoptosis by blocking the function enzymes associated with cell proliferation.
Interestingly, in green fluorescent protein-chimeric animals, treatment with fastuosain did not change the number of cells that migrated to the lung, compared to PBS-injected control mice, but the number of positive major histocompatibility complex class II cells associated with antigens was increased significantly.
In other words, fastuosain anti-lung cancer activity is mainly involved in the direct effect of the enzyme and elicitation of protective antibodies.
Taken altogether, bromelain may be considered supplements for the prevention and treatment of lung cancer, pending to the confirmation of the larger sample size and multicenter human study.
Intake of bromelain in the form of supplements should be taken with extreme care to prevent overdose acute liver toxicity.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Antitumor effects in vitro and in vivo and mechanisms of protection against melanoma B16F10-Nex2 cells by fastuosain, a cysteine proteinase from Bromelia fastuosa by Guimarães-Ferreira CA1, Rodrigues EG, Mortara RA, Cabral H, Serrano FA, Ribeiro-dos-Santos R, Travassos LR. (PubMed)
(2) Melanoma heterogeneity: differential, invasive, metastatic properties and profiles of cathepsin B, D and L activities in subclones of the B16F10-NEX2 cell line by Freitas ZF1, Rodrigues EG, Oliveira V, Carmona AK, Travassos LR. (PubMed)
(3) Smoking and lung cancer by Ozlü T1, Bülbül Y. (PubMed)
The lung is a vital organ of the human being, located near the backbone on either side of the heart with functions of inhaling oxygen from the air then transporting them to the bloodstream and exhaling carbon dioxide from the bloodstream.
According to the statistics, in the US, lung cancer is the leading cause of cancer deaths. In n 2007. lung caused the death of 158,683 Americans, including 88,329 men and 70,354 women i
There are several types of lung cancer including
1. Non-small cell lung cancer
Non-small cell lung cancer, the most common type of lung cancer grown and spread methodically and predictably, includes
* Squamous-cell carcinoma often found in an outer area of the lung.
*Large-cell carcinoma found in the center of the lung by an air tube.
* Adenocarcinoma found in any part of the lung.
2. Small cell lung cancer
Small cell lung cancer is an aggressive type of lung cancer. The cells of small cell cancer have been found to spread to distant parts of the body in a relatively early stage.
* Small cell carcinoma in which the cells are small, round and resemble oats.
* Mixed small cell/large cell carcinoma, the malignant tumor is found in combining components of small cell lung carcinoma with large cell lung carcinoma.
* Combined small cell carcinoma, the malignant tumor is found in combining of a component of small cell lung carcinoma with components of non-small cell lung carcinoma
Out of many risk factors associated with the onset of lung cancer, some researchers suggested smokers are at substantial risk of the disease.
Dr. Ozlü T the lead scientist wrote, "It is estimated that deaths attributable to tobacco use will rise to 10 million by 2025, and one-third of all adult deaths are expected to be related to cigarette smoking".
And, "Tobacco use has been reported to be the main cause of 90% of male and 79% of female lung cancers. 90% of deaths from lung cancer are estimated to be due to smoking. The risk of lung cancer development is 20-40 times higher in lifelong smokers compared to non-smokers".
The results strongly suggested that if you are a smoker, your risk of lung cancer developing is rocketing.
Bromelain, a proteolytic enzyme found in pineapples (Ananas comosus) has been used in traditional medicine as an inflammatory agent and to treat pains, strains, and muscle aches and pains and ease back pain and chronic joint pain, skin diseases, etc.
With an aim to find a natural ingredient against lung cancer, researchers examined the effects of the antitumor effect of fastuosain, a cysteine proteinase from Bromelia fastuosa on the intravenous model of lung colonization in C57Bl/6 mice.
According to the tested assays, fastuosain showed reduced expression of the marker of cancer progression (CD44) and decreased invasion by inhibiting cancer cell communication and inflammation in tumor cells.
Furthermore, fastuosain also induced cancer apoptosis by blocking the function enzymes associated with cell proliferation.
Interestingly, in green fluorescent protein-chimeric animals, treatment with fastuosain did not change the number of cells that migrated to the lung, compared to PBS-injected control mice, but the number of positive major histocompatibility complex class II cells associated with antigens was increased significantly.
In other words, fastuosain anti-lung cancer activity is mainly involved in the direct effect of the enzyme and elicitation of protective antibodies.
Taken altogether, bromelain may be considered supplements for the prevention and treatment of lung cancer, pending to the confirmation of the larger sample size and multicenter human study.
Intake of bromelain in the form of supplements should be taken with extreme care to prevent overdose acute liver toxicity.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Antitumor effects in vitro and in vivo and mechanisms of protection against melanoma B16F10-Nex2 cells by fastuosain, a cysteine proteinase from Bromelia fastuosa by Guimarães-Ferreira CA1, Rodrigues EG, Mortara RA, Cabral H, Serrano FA, Ribeiro-dos-Santos R, Travassos LR. (PubMed)
(2) Melanoma heterogeneity: differential, invasive, metastatic properties and profiles of cathepsin B, D and L activities in subclones of the B16F10-NEX2 cell line by Freitas ZF1, Rodrigues EG, Oliveira V, Carmona AK, Travassos LR. (PubMed)
(3) Smoking and lung cancer by Ozlü T1, Bülbül Y. (PubMed)
Saturday, September 19, 2020
Fennel May Improve Your Heart Functioning Naturally and Permanently, Studies Showed
Fennel may have a potential and positive effect in improvement of cardiovascular activity, some scientists suggested.
The results of vascular and cardiovascular protective effect were reported by numbers of universities including the Birzeit University and published on online medical literature.
Fennel (Foeniculum vulgare) is a plant species of genus, belongings to Apiaceae (Umbelliferae), native to the Mediterranean, used in traditional and herbal medicine as warming, carminative, antispasmodic, antidepressant agent and to stimulate the appetite, ease indigestion, soothe coughing, reduce intestinal spasms, to regulate the menstrual cycle and relieve PMS,...
Nutrients
1. Carbohydrates
2. Fiber
3. Protein
4. Thiamine (Vitamin B1)
5. Riboflavin (Vitamin B2)
6. Niacin (Vitamin B3)
7. Pantothenic acid (B5)
8. Vitamin B6
9. Folate (Vitamin B9)
10. Vitamin C
11. Calcium
12. Copper
13. Iron
14. Magnesium
15. Molybdenum
16. Phosphorus
17. Potassium
18. Zinc
In the study to investigate the vascular effects of aqueous extracts of Foeniculum vulgare leaves in pentobarbital-anaesthetised rats, researchers found that intravenous administration of the lyophilized boiled water extract exerted a significant dose-related reduction in arterial blood pressure, without affecting the heart rate or respiratory rate in compared to histamine antagonists.
However, the application of non-boiled aqueous extract showed very little hypotensive activity.
In contrast to the conventional medicine histamine antagonists, the hypotensive effect of the boiling water extract appeared not to be mediated by adrenergic, muscarinic, ganglionic, or serotonergic receptors.
Furthermore, in the examine the cardiovascular effect of the main component of the oil, anethole isolated from on tested guinea pig fennel oil in inhibited arachidonic acid, collagen-, ADP- and U46619-induced aggregation, researchers found that application of anethole displayed comparable NO-independent vasorelaxant activity at antiplatelet concentrations.
Anethole also prevented thrombin-induced clot retraction at concentrations similar to fennel oil in comparison of U46619-induced aggregation (IC(50) from 4 to 147 microg ml(-1)). These results were confirmed in tested mice with application F. Vulgare essential oil and anethole in a subacute treatment of 30 mg kg(-1)day(-1) for 5 days.
F. Vulgare essential oil and anethole also showed significant antithrombotic activity in prevented paralysis induced by collagen-epinephrine intravenous injection with 70% and 83% protection, respectively.
In the rat model, both F. Vulgare essential oil and anethole (100 mg kg(-1) oral administration) provided significant protection toward ethanol-induced gastric lesions.
After taking into account of other co and confounders, togther with the collected information Dr. Tognolini M, the lead author said, " F. vulgare essential oil, and its main component anethole, a safe antithrombotic activity that seems due to their broad spectrum antiplatelet activity, clot destabilizing effect, and vasorelaxant action".
Further to reassess other cardiovascular activity of Foeniculum vulgare L, researchers at the UFR Physiologie-Pharmacologie, launched an investigation to compare the effects of Marrubium vulgare L. and Foeniculum vulgare L. in spontaneously hypertensive rats (SHR).
Interestingly, the oral application of Foeniculum extract exerted lowered the systolic blood pressure of SHR without induced change of normotensive Wistar-Kyoto rats (WKY).
These results were probably associated with to function of Foeniculum in increased water, sodium, and potassium excretion.
More importantly, Foeniculum extract hypertensive efficacy was decreased substantially in rat and mice presented with N-nitro-L-arginine.
The results indicated that fennel demonstrated the vascular protective activity as a diuretic and a natriuretic.
Taken together, Fennel and its essential oil and bioactive compound anethole may be considered as a function substance in promoting cardiovascular and vascular activity, particularly in animal models with a high risk of cardiovascular disease.
Intake of fennel extract should be taken with extreme care as overdoses may induce liver toxicity.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Loose Weight
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Home page http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrients, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.
Sources
(1) Protective effect of Foeniculum vulgare essential oil and anethole in an experimental model of thrombosis by Tognolini M1, Ballabeni V, Bertoni S, Bruni R, Impicciatore M, Barocelli E.(PubMed)
(2) Pharmacological evidence of hypotensive activity of Marrubium vulgare and Foeniculum vulgare in spontaneously hypertensive rat by El Bardai S1, Lyoussi B, Wibo M, Morel N.(PubMed)
(3) The vascular action of aqueous extracts of Foeniculum vulgare leaves by Abdul-Ghani AS1, Amin R.(PubMed)
The results of vascular and cardiovascular protective effect were reported by numbers of universities including the Birzeit University and published on online medical literature.
Fennel (Foeniculum vulgare) is a plant species of genus, belongings to Apiaceae (Umbelliferae), native to the Mediterranean, used in traditional and herbal medicine as warming, carminative, antispasmodic, antidepressant agent and to stimulate the appetite, ease indigestion, soothe coughing, reduce intestinal spasms, to regulate the menstrual cycle and relieve PMS,...
Nutrients
1. Carbohydrates
2. Fiber
3. Protein
4. Thiamine (Vitamin B1)
5. Riboflavin (Vitamin B2)
6. Niacin (Vitamin B3)
7. Pantothenic acid (B5)
8. Vitamin B6
9. Folate (Vitamin B9)
10. Vitamin C
11. Calcium
12. Copper
13. Iron
14. Magnesium
15. Molybdenum
16. Phosphorus
17. Potassium
18. Zinc
In the study to investigate the vascular effects of aqueous extracts of Foeniculum vulgare leaves in pentobarbital-anaesthetised rats, researchers found that intravenous administration of the lyophilized boiled water extract exerted a significant dose-related reduction in arterial blood pressure, without affecting the heart rate or respiratory rate in compared to histamine antagonists.
However, the application of non-boiled aqueous extract showed very little hypotensive activity.
In contrast to the conventional medicine histamine antagonists, the hypotensive effect of the boiling water extract appeared not to be mediated by adrenergic, muscarinic, ganglionic, or serotonergic receptors.
Furthermore, in the examine the cardiovascular effect of the main component of the oil, anethole isolated from on tested guinea pig fennel oil in inhibited arachidonic acid, collagen-, ADP- and U46619-induced aggregation, researchers found that application of anethole displayed comparable NO-independent vasorelaxant activity at antiplatelet concentrations.
Anethole also prevented thrombin-induced clot retraction at concentrations similar to fennel oil in comparison of U46619-induced aggregation (IC(50) from 4 to 147 microg ml(-1)). These results were confirmed in tested mice with application F. Vulgare essential oil and anethole in a subacute treatment of 30 mg kg(-1)day(-1) for 5 days.
F. Vulgare essential oil and anethole also showed significant antithrombotic activity in prevented paralysis induced by collagen-epinephrine intravenous injection with 70% and 83% protection, respectively.
In the rat model, both F. Vulgare essential oil and anethole (100 mg kg(-1) oral administration) provided significant protection toward ethanol-induced gastric lesions.
After taking into account of other co and confounders, togther with the collected information Dr. Tognolini M, the lead author said, " F. vulgare essential oil, and its main component anethole, a safe antithrombotic activity that seems due to their broad spectrum antiplatelet activity, clot destabilizing effect, and vasorelaxant action".
Further to reassess other cardiovascular activity of Foeniculum vulgare L, researchers at the UFR Physiologie-Pharmacologie, launched an investigation to compare the effects of Marrubium vulgare L. and Foeniculum vulgare L. in spontaneously hypertensive rats (SHR).
Interestingly, the oral application of Foeniculum extract exerted lowered the systolic blood pressure of SHR without induced change of normotensive Wistar-Kyoto rats (WKY).
These results were probably associated with to function of Foeniculum in increased water, sodium, and potassium excretion.
More importantly, Foeniculum extract hypertensive efficacy was decreased substantially in rat and mice presented with N-nitro-L-arginine.
The results indicated that fennel demonstrated the vascular protective activity as a diuretic and a natriuretic.
Taken together, Fennel and its essential oil and bioactive compound anethole may be considered as a function substance in promoting cardiovascular and vascular activity, particularly in animal models with a high risk of cardiovascular disease.
Intake of fennel extract should be taken with extreme care as overdoses may induce liver toxicity.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Loose Weight
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Home page http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrients, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.
Sources
(1) Protective effect of Foeniculum vulgare essential oil and anethole in an experimental model of thrombosis by Tognolini M1, Ballabeni V, Bertoni S, Bruni R, Impicciatore M, Barocelli E.(PubMed)
(2) Pharmacological evidence of hypotensive activity of Marrubium vulgare and Foeniculum vulgare in spontaneously hypertensive rat by El Bardai S1, Lyoussi B, Wibo M, Morel N.(PubMed)
(3) The vascular action of aqueous extracts of Foeniculum vulgare leaves by Abdul-Ghani AS1, Amin R.(PubMed)
Friday, September 18, 2020
Herbal Angelica Sinensis, A Potential Anti Weight Gain Remedy
Obesity is a medical condition caused by excess body fat accumulated to some extent that impacts personal health. The hallmark of obesity is attenuated metabolism and structural cell changes in the obese fat observed by reducing metabolic activity.
According to the Body Mass Index(BMI), people who have a BMI between 25 to 29.9 are considered overweight and a BMI of over 30 is an indication of obesity.
The formula of the BMI indexBMI= weight (kg)/ height (m2)
According to the statistic, 68% of the American population is either overweight or obese. However,
in 2016, more than 1.9 billion adults, 18 years and older, were overweight, including over 650 million were obese worldwide.
Visceral fat obesity is associated with 90% of patients with ischemic heart disease. In obese, the accumulation of visceral fat is predominant in the intra-abdominal cavity.
Visceral fat is a layer of fat that surrounds the organs. Overexpression of visceral fat has been found to promote insulin resistance, diabetes, heart disease, and inflammation.
However, in non-obese subjects, visceral fat accumulation is correlated with glucose intolerance, hyperlipidemia, and hypertension.
Obesity rates have increased for all age groups in the US over the last several decades, coincidently with the periods that promoted the Western diet.
Weight gain is an increase in body weight associated with some parameters, including increased muscle mass, fat deposits, excess fluids such as water, or other factors.
However, weight gain has also been found to be induced by serious medical conditions.
On finding a natural ingredient for the prevention and treatment of obesity, scientists examined the radix Angelica sinensis (RAS) suppressed body weight by altering the expression of the fat mass and obesity-associated (FTO) gene in an animal model.
Angelica or Dang Gui is a herb of Genus Angelica from the family Apiaceae, indigenous to China.
The herb has been used as a Queen herb in traditional Chinese medicine antispasmodic and vasodilatory agent, and to balance the hormones in women for a normal menstrual cycle and menstruation and strengthen heart, spleen, kidneys, and liver for both men and women, etc. In other words, it is used to treat gynecological ailments, fatigue, mild anemia, and high blood pressure. It has analgesic, anti-inflammatory, etc.
According to tested analysis in mice fed with high-fat diet (HFD)-induced obesity,
* 36 differentially-expressed genes (DEGs) associated with the increased onset of obesity were found in adipose tissues from the RAS supplementation group (DH) and control group (HC).
* Six out of the 36 DEGs identified to be involved in lipid metabolism, with the APOA2 gene a potential anti-obesogenic influence were inhibited by the injection of RAS compared to control.
In other words, RAS supplementation in HFD-induced obese mice was associated with an anti-obesogenic global transcriptomic response.
Based on the results, researchers suggest, "This study provides insight into potential applications of RAS in obesity therapy".
Taken altogether, Dandelion may be considered a remedy for the treatment of weight gain in obese, pending to the confirmation of the larger sample size and multicenter human study.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You. How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Anti-obesity effect of radix Angelica sinensis and candidate causative genes in transcriptome analyses of adipose tissues in high-fat diet-induced mice by Zhong T1, Zhang H1, Duan X1, Hu J1, Wang L1, Li L1, Zhang H1, Niu L. (PubMed)
According to the Body Mass Index(BMI), people who have a BMI between 25 to 29.9 are considered overweight and a BMI of over 30 is an indication of obesity.
The formula of the BMI indexBMI= weight (kg)/ height (m2)
According to the statistic, 68% of the American population is either overweight or obese. However,
in 2016, more than 1.9 billion adults, 18 years and older, were overweight, including over 650 million were obese worldwide.
Visceral fat obesity is associated with 90% of patients with ischemic heart disease. In obese, the accumulation of visceral fat is predominant in the intra-abdominal cavity.
Visceral fat is a layer of fat that surrounds the organs. Overexpression of visceral fat has been found to promote insulin resistance, diabetes, heart disease, and inflammation.
However, in non-obese subjects, visceral fat accumulation is correlated with glucose intolerance, hyperlipidemia, and hypertension.
Obesity rates have increased for all age groups in the US over the last several decades, coincidently with the periods that promoted the Western diet.
Weight gain is an increase in body weight associated with some parameters, including increased muscle mass, fat deposits, excess fluids such as water, or other factors.
However, weight gain has also been found to be induced by serious medical conditions.
On finding a natural ingredient for the prevention and treatment of obesity, scientists examined the radix Angelica sinensis (RAS) suppressed body weight by altering the expression of the fat mass and obesity-associated (FTO) gene in an animal model.
Angelica or Dang Gui is a herb of Genus Angelica from the family Apiaceae, indigenous to China.
The herb has been used as a Queen herb in traditional Chinese medicine antispasmodic and vasodilatory agent, and to balance the hormones in women for a normal menstrual cycle and menstruation and strengthen heart, spleen, kidneys, and liver for both men and women, etc. In other words, it is used to treat gynecological ailments, fatigue, mild anemia, and high blood pressure. It has analgesic, anti-inflammatory, etc.
According to tested analysis in mice fed with high-fat diet (HFD)-induced obesity,
* 36 differentially-expressed genes (DEGs) associated with the increased onset of obesity were found in adipose tissues from the RAS supplementation group (DH) and control group (HC).
* Six out of the 36 DEGs identified to be involved in lipid metabolism, with the APOA2 gene a potential anti-obesogenic influence were inhibited by the injection of RAS compared to control.
In other words, RAS supplementation in HFD-induced obese mice was associated with an anti-obesogenic global transcriptomic response.
Based on the results, researchers suggest, "This study provides insight into potential applications of RAS in obesity therapy".
Taken altogether, Dandelion may be considered a remedy for the treatment of weight gain in obese, pending to the confirmation of the larger sample size and multicenter human study.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You. How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Anti-obesity effect of radix Angelica sinensis and candidate causative genes in transcriptome analyses of adipose tissues in high-fat diet-induced mice by Zhong T1, Zhang H1, Duan X1, Hu J1, Wang L1, Li L1, Zhang H1, Niu L. (PubMed)
Thursday, September 17, 2020
Cranberry, the Best in the Management of Obesity, Researchers Say
Obesity is a chronic condition characterized by excess body fat that has accumulated over time. People with a BMI of over 30 is considered obese.
Similarly, overweight is a condition of excess body weight relative to height. People with a BMI ranged from 25 to 29.9 is considered overweight.
According to the statistics, over 30 % of the American population is obese. Obesity has been found to induce adverse effects on nearly every system of the human body, leading to an increased risk of numerous diseases, including diabetes and cardiovascular disease.
Furthermore, the rate of obesity in the US and Canada continues to climb at an alarming rate, leading to significant burdens to the country's economy and health care system.
Epidemiologically, the most common symptoms of obesity are breathlessness, increased sweating, inability to cope with physical activity, feeling very tired every day, back and joint pains, low confidence, and self-esteem and feeling isolation
According to the CDC, the most common complications associated with obesity are coronary heart disease, stroke, type 2 diabetes, cancer of breast, colon, endometrial, gallbladder, kidney, and liver and sleep apnea.
Currently, there is no effective treatment of the disease. However, some researchers suggested that combat the powerful environmental factors that influence eating and physical activity may be the best approach to reduce the risk of obesity.
Dr. EunSeok Cha, the lead scientist wrote, "Obesity among young adults is a growing problem in the United States and is related to unhealthy lifestyle habits such as high caloric intake and inadequate exercise. Accurate assessment of lifestyle habits across obesity stages is important for informing age-specific intervention strategies to prevent and reduce obesity progression".
And, "Overweight and obese young adults can promote their cardiometabolic health with healthy lifestyles. To take action, young adults need practical and strategic dietary advice about beverage choices, diet quality, and macronutrient and micronutrient sources. In addition, increasing overall activity and minimizing sedentary behavior needs to be emphasized for young adults to achieve physical activity goals.".
In other words, by changing to a healthy lifestyle such as a healthy diet and moderate exercise, over a long-term obese is controllable.
Cranberry is an evergreen dwarf shrub, genus Vaccinium, belongings to the family Ericaceae, native to Northern America and Southern Asia. Because of its health benefits, cranberry has been cultivated in some parts of the world for commercial profit and used in traditional and herbal medicine to treat wounds, urinary disorders, diarrhea, diabetes, stomach ailments, and liver problems.
On finding a potential compound for the treatment of diseases associated with oxidative stress, researchers investigated the anti-adipogenic effect of the polyphenol-rich extract obtained from chokeberry Aronia melanocarpa (Michx.) Elliot, raspberry Rubus idaeus L., bilberry Vaccinium myrtillus L., and cranberry Vaccinium macrocarpon Aiton fruits.
According to the results from the analysis, the preparations ranged from 25-100 μg/mL not only significantly decreased lipid accumulation but also inhibited the expression of reactive oxygen species in the adipocytes without showing cytotoxicity.
The Real-time PCR analysis also revealed that the extract at a concentration of 100 μg/mL suppressed the process of cell differentiation of adipogenesis and lipogenesis that converts triglyceride for storage in fat via inhibiting the gene expression (PPARγ) of energy metabolism and genes associated with adipogenesis (C/EBPα) and lipogenesis (SREBP1).
In 3T3-L1 adipocytes, the expression of adiponectin involved in regulating glucose levels as well as fatty acid breakdown was increased by 4.4 fold whereas hormone leptin found in high levels of obese subjects was decreased by 90% by the extracts.
Based on the findings, researchers said, " the analyzed extract may be a promising source of bioactive compounds that support long-term weight maintenance and promote the effective management of obesity".
Taken altogether, cranberry combined with other herbal medicine may be considered a remedy for the management of obesity, pending to the confirmation of the larger sample size and multicenter human study.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Inhibitory activity of chokeberry, bilberry, raspberry and cranberry polyphenol-rich extract towards adipogenesis and oxidative stress in differentiated 3T3-L1 adipose cells by Kowalska K1, Olejnik A1, Szwajgier D2, Olkowicz M. (PubMed)
(2) Lifestyle habits and obesity progression in overweight and obese American young adults: Lessons for promoting cardiometabolic health by EunSeok Cha, PhD, MPH, MSN, CDE, RN, Margeaux K. Akazawa, MPH, Kevin H. Kim, PhD,*Colleen R. Dawkins, MSN, FNP-BC, RD, Hannah M. Lerner, BS, Guillermo Umpierrez, MD, FACP, FACE, and Sandra B. Dunbar, PhD, FAAN, FAHA, RN. (PMC)
Similarly, overweight is a condition of excess body weight relative to height. People with a BMI ranged from 25 to 29.9 is considered overweight.
According to the statistics, over 30 % of the American population is obese. Obesity has been found to induce adverse effects on nearly every system of the human body, leading to an increased risk of numerous diseases, including diabetes and cardiovascular disease.
Furthermore, the rate of obesity in the US and Canada continues to climb at an alarming rate, leading to significant burdens to the country's economy and health care system.
Epidemiologically, the most common symptoms of obesity are breathlessness, increased sweating, inability to cope with physical activity, feeling very tired every day, back and joint pains, low confidence, and self-esteem and feeling isolation
According to the CDC, the most common complications associated with obesity are coronary heart disease, stroke, type 2 diabetes, cancer of breast, colon, endometrial, gallbladder, kidney, and liver and sleep apnea.
Currently, there is no effective treatment of the disease. However, some researchers suggested that combat the powerful environmental factors that influence eating and physical activity may be the best approach to reduce the risk of obesity.
Dr. EunSeok Cha, the lead scientist wrote, "Obesity among young adults is a growing problem in the United States and is related to unhealthy lifestyle habits such as high caloric intake and inadequate exercise. Accurate assessment of lifestyle habits across obesity stages is important for informing age-specific intervention strategies to prevent and reduce obesity progression".
And, "Overweight and obese young adults can promote their cardiometabolic health with healthy lifestyles. To take action, young adults need practical and strategic dietary advice about beverage choices, diet quality, and macronutrient and micronutrient sources. In addition, increasing overall activity and minimizing sedentary behavior needs to be emphasized for young adults to achieve physical activity goals.".
In other words, by changing to a healthy lifestyle such as a healthy diet and moderate exercise, over a long-term obese is controllable.
Cranberry is an evergreen dwarf shrub, genus Vaccinium, belongings to the family Ericaceae, native to Northern America and Southern Asia. Because of its health benefits, cranberry has been cultivated in some parts of the world for commercial profit and used in traditional and herbal medicine to treat wounds, urinary disorders, diarrhea, diabetes, stomach ailments, and liver problems.
On finding a potential compound for the treatment of diseases associated with oxidative stress, researchers investigated the anti-adipogenic effect of the polyphenol-rich extract obtained from chokeberry Aronia melanocarpa (Michx.) Elliot, raspberry Rubus idaeus L., bilberry Vaccinium myrtillus L., and cranberry Vaccinium macrocarpon Aiton fruits.
According to the results from the analysis, the preparations ranged from 25-100 μg/mL not only significantly decreased lipid accumulation but also inhibited the expression of reactive oxygen species in the adipocytes without showing cytotoxicity.
The Real-time PCR analysis also revealed that the extract at a concentration of 100 μg/mL suppressed the process of cell differentiation of adipogenesis and lipogenesis that converts triglyceride for storage in fat via inhibiting the gene expression (PPARγ) of energy metabolism and genes associated with adipogenesis (C/EBPα) and lipogenesis (SREBP1).
In 3T3-L1 adipocytes, the expression of adiponectin involved in regulating glucose levels as well as fatty acid breakdown was increased by 4.4 fold whereas hormone leptin found in high levels of obese subjects was decreased by 90% by the extracts.
Based on the findings, researchers said, " the analyzed extract may be a promising source of bioactive compounds that support long-term weight maintenance and promote the effective management of obesity".
Taken altogether, cranberry combined with other herbal medicine may be considered a remedy for the management of obesity, pending to the confirmation of the larger sample size and multicenter human study.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Inhibitory activity of chokeberry, bilberry, raspberry and cranberry polyphenol-rich extract towards adipogenesis and oxidative stress in differentiated 3T3-L1 adipose cells by Kowalska K1, Olejnik A1, Szwajgier D2, Olkowicz M. (PubMed)
(2) Lifestyle habits and obesity progression in overweight and obese American young adults: Lessons for promoting cardiometabolic health by EunSeok Cha, PhD, MPH, MSN, CDE, RN, Margeaux K. Akazawa, MPH, Kevin H. Kim, PhD,*Colleen R. Dawkins, MSN, FNP-BC, RD, Hannah M. Lerner, BS, Guillermo Umpierrez, MD, FACP, FACE, and Sandra B. Dunbar, PhD, FAAN, FAHA, RN. (PMC)
Wednesday, September 16, 2020
Herbal Bilberry Effects On Locomotion In Patients with Neurodegenerative Disease
Locomotion is the ability to move from place to the other. In humans, locomotion controlled by the cerebellum is a complex process that requires the integration of central and peripheral nervous signaling coordinated by the muscles.
In other words, every time you move any part of the body, the cerebellum fires into action.
Damage of the cerebellum of the brain has been found to induce difficulty with balance, coordination, and fine motor skills in patients.
Besides neurodegenerative diseases, alcohol abuse, certain medications, stroke, tumor, cerebral palsy, brain degeneration, and multiple sclerosis are the most common risk factors which can affect the brain locomotion control.
In conventional medicine, depending on the causes that affect the locomotion, adaptive devices may be introduced to maintain independence. Other therapies such as physical, occupational, and speech therapy with moderate exercise have been found to be helpful.
Bilberry is a species of low-growing shrubs in the genus Vaccinium, belonging to the family Ericaceae, native to Northern Europe.
The plant berry has been used as herbs in traditional medicine for the treatment of acute and chronic diarrhea, gastritis, gastric ulcer, and duodenal ulcer, enterocolitis, ulcerative colitis, anemia, cystitis, kidney disease, and psoriasis, diabetes, etc.
On finding a potential compound for the improvement of locomotion in patients with neurodegenerative disease, researchers examined the possible effects of prolonged administration of lyophilized Vaccinium berries (blueberry, bilberry) on cognitive performance against the incidence of degenerative disorders.
Mice selected to the study were observed by step-down inhibitory avoidance, open field, elevated plus-maze, and radial maze tasks. The lyophilized berries were administered for 30 days before the first training.
According to the tested assays, lyophilized berries significantly enhanced locomotion by increasing the number of crossings in the first exposure to the open field.
Additionally, short term treatment with lyophilized berries also improves rat performance on the elevated plus-maze task.
In other words, lyophilized berries inhibited the neuro deficits associated with inactivity behavior such as anxiety.
Taken altogether, bilberry processed abundantly bioactive compound anthocyanoside may be considered a functioning remedy for the improvement of locomotion in patients with neurodegenerative diseases, pending to the validation of a larger sample size and multicenter human study.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
References
(1) Effect of lyophilised Vaccinium berries on memory, anxiety and locomotion in adult rats by Ramirez MR1, Izquierdo I, do Carmo Bassols Raseira M, Zuanazzi JA, Barros D, Henriques AT. (PubMed)
In other words, every time you move any part of the body, the cerebellum fires into action.
Damage of the cerebellum of the brain has been found to induce difficulty with balance, coordination, and fine motor skills in patients.
Besides neurodegenerative diseases, alcohol abuse, certain medications, stroke, tumor, cerebral palsy, brain degeneration, and multiple sclerosis are the most common risk factors which can affect the brain locomotion control.
In conventional medicine, depending on the causes that affect the locomotion, adaptive devices may be introduced to maintain independence. Other therapies such as physical, occupational, and speech therapy with moderate exercise have been found to be helpful.
Bilberry is a species of low-growing shrubs in the genus Vaccinium, belonging to the family Ericaceae, native to Northern Europe.
The plant berry has been used as herbs in traditional medicine for the treatment of acute and chronic diarrhea, gastritis, gastric ulcer, and duodenal ulcer, enterocolitis, ulcerative colitis, anemia, cystitis, kidney disease, and psoriasis, diabetes, etc.
On finding a potential compound for the improvement of locomotion in patients with neurodegenerative disease, researchers examined the possible effects of prolonged administration of lyophilized Vaccinium berries (blueberry, bilberry) on cognitive performance against the incidence of degenerative disorders.
Mice selected to the study were observed by step-down inhibitory avoidance, open field, elevated plus-maze, and radial maze tasks. The lyophilized berries were administered for 30 days before the first training.
According to the tested assays, lyophilized berries significantly enhanced locomotion by increasing the number of crossings in the first exposure to the open field.
Additionally, short term treatment with lyophilized berries also improves rat performance on the elevated plus-maze task.
In other words, lyophilized berries inhibited the neuro deficits associated with inactivity behavior such as anxiety.
Taken altogether, bilberry processed abundantly bioactive compound anthocyanoside may be considered a functioning remedy for the improvement of locomotion in patients with neurodegenerative diseases, pending to the validation of a larger sample size and multicenter human study.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
References
(1) Effect of lyophilised Vaccinium berries on memory, anxiety and locomotion in adult rats by Ramirez MR1, Izquierdo I, do Carmo Bassols Raseira M, Zuanazzi JA, Barros D, Henriques AT. (PubMed)
Tuesday, September 15, 2020
Herbal Bilberry Protects Us Against Diseases Associated with Oxidative Stress
Oxidative stress occurs when the ratio of the levels of free radicals and antioxidants is imbalanced. In other words, oxidative stress is a result caused by either overexpression of free radicals or depletion of antioxidant enzymes produced by the host.
Free radicals are an unstable atom with a lone electron in the outer ring. Therefore, in order to become stable, free radicals must steal or donate an electron from other stable atoms, leading to a chain reaction which is highly reactive that can be stopped until all single electron is paired or inhibited by antioxidants.
Antioxidants are stable atoms which inhibit oxidation.
Free radical exists in and outside our body. Externally, the air we breathe, the food we eat and environmental toxins and internally, the cell's metabolism, all contribute to the production of free radicals.
On the other hand, antioxidants can either be produced by the body internally or induced by the consumption of antioxidant-rich externally.
Under normal conditions, in a healthy individual, the production of antioxidant enzymes by the body is more than enough to counter the levels of free radicals in the body. However, for people with a weakened immune system or immature immune system, the intake of dietary sources of antioxidant-rich foods may be necessary.
Maintaining the healthy levels of antioxidants in the body is the best way to prevent diseases associated with oxidative stress, including atherosclerosis, cancer, diabetics, rheumatoid arthritis.
Bilberry is a species of low-growing shrubs in the genus Vaccinium, belonging to the family Ericaceae, native to Northern Europe.
The plant berry has been used as herbs in traditional medicine for the treatment of acute and chronic diarrhea, gastritis, gastric ulcer, and duodenal ulcer, enterocolitis, ulcerative colitis, anemia, cystitis, kidney disease, and psoriasis, diabetes, etc.
In the urgency to discover a bioactive compound for the treatment of diseases associated with oxidative stress, researchers examined the anti-adipogenic effect of the polyphenol-rich extract obtained from chokeberry Aronia melanocarpa (Michx.) Elliot, raspberry Rubus idaeus L., bilberry Vaccinium myrtillus L., and cranberry Vacciniummacrocarpon Aiton fruits.
According to the tested assays, treatment with the extract (25-100 μg/mL) significantly decreased lipid accumulation and reactive oxygen species generation in adipocytes without showing cytotoxicity.
The extract at a concentration of 100 μg/mL suppressed adipogenesis and lipogenesis by inhibiting the receptors involved gene expression.
Moreover, the extract also exerted the anti-adipogenic effect by a significant increase in the expression of adiponectin (4.4-fold) and decreased leptin expression (90%) made by adipose cells.
In the study to investigate the antihyperglycemic effects of four extracts obtained from leaves and fruits of Vaccinium myrtillus and Vacciniumcorymbosum in diabetic rats randomly divided into seven equal groups: NC-normal control, DC-diabetic control, PC-positive control treated with metformin, VML-received V. myrtillus leaf extract, VMLF-received VML, and fruit extract, VCL-received V. corymbosum leaf extract, and VCLF-received VCL and fruit extract, researchers found that according to the Bodyweight and glucose levels monitored every second week and after 8 weeks of treatment, serum glucose, insulin, and malondialdehyde measurement
* VML treated group showed no significant decrease in weight compared to a decrease in body weight in all diabetic groups in the first weeks.
* VML, VMLF, and VCLF groups demonstrated a decrease in blood glucose levels compared to the increase in the DC, PC, and VCL groups.
* Additionally, serum insulin and glucose levels at the end of the experiment were lower in VML, VMLF, and VCLF groups compared to other unimproved groups.
* More importantly, V. myrtillus extracts prevented the development of cataract compared with the DC group (P < .05).
The findings suggested that bilberry processes antioxidative stress activity against the onset of obesity and retinal degenerative disease.
Taken altogether, bilberry processed abundantly bioactive compounds may be considered a functioning remedy for the prevention and treatment of diseases associated with oxidative stress, pending to the validation of a larger sample size and multicenter human study.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
References
(1) Inhibitory activity of chokeberry, bilberry, raspberry and cranberry polyphenol-rich extract towards adipogenesis and oxidative stress in differentiated 3T3-L1 adipose cells by Kowalska K1, Olejnik A1, Szwajgier D2, Olkowicz M. (PubMed)
(2) Vaccinium Extracts as Modulators in Experimental Type 1 Diabetes by Ştefănescu Braic R1, Vari C2, Imre S3, Huţanu A4, Fogarasi E5, Todea T6, Groşan A2, Eşianu S1, Laczkó-Zöld E1, Dogaru M. (PubMed)
Free radicals are an unstable atom with a lone electron in the outer ring. Therefore, in order to become stable, free radicals must steal or donate an electron from other stable atoms, leading to a chain reaction which is highly reactive that can be stopped until all single electron is paired or inhibited by antioxidants.
Antioxidants are stable atoms which inhibit oxidation.
Free radical exists in and outside our body. Externally, the air we breathe, the food we eat and environmental toxins and internally, the cell's metabolism, all contribute to the production of free radicals.
On the other hand, antioxidants can either be produced by the body internally or induced by the consumption of antioxidant-rich externally.
Under normal conditions, in a healthy individual, the production of antioxidant enzymes by the body is more than enough to counter the levels of free radicals in the body. However, for people with a weakened immune system or immature immune system, the intake of dietary sources of antioxidant-rich foods may be necessary.
Maintaining the healthy levels of antioxidants in the body is the best way to prevent diseases associated with oxidative stress, including atherosclerosis, cancer, diabetics, rheumatoid arthritis.
Bilberry is a species of low-growing shrubs in the genus Vaccinium, belonging to the family Ericaceae, native to Northern Europe.
The plant berry has been used as herbs in traditional medicine for the treatment of acute and chronic diarrhea, gastritis, gastric ulcer, and duodenal ulcer, enterocolitis, ulcerative colitis, anemia, cystitis, kidney disease, and psoriasis, diabetes, etc.
In the urgency to discover a bioactive compound for the treatment of diseases associated with oxidative stress, researchers examined the anti-adipogenic effect of the polyphenol-rich extract obtained from chokeberry Aronia melanocarpa (Michx.) Elliot, raspberry Rubus idaeus L., bilberry Vaccinium myrtillus L., and cranberry Vacciniummacrocarpon Aiton fruits.
According to the tested assays, treatment with the extract (25-100 μg/mL) significantly decreased lipid accumulation and reactive oxygen species generation in adipocytes without showing cytotoxicity.
The extract at a concentration of 100 μg/mL suppressed adipogenesis and lipogenesis by inhibiting the receptors involved gene expression.
Moreover, the extract also exerted the anti-adipogenic effect by a significant increase in the expression of adiponectin (4.4-fold) and decreased leptin expression (90%) made by adipose cells.
In the study to investigate the antihyperglycemic effects of four extracts obtained from leaves and fruits of Vaccinium myrtillus and Vacciniumcorymbosum in diabetic rats randomly divided into seven equal groups: NC-normal control, DC-diabetic control, PC-positive control treated with metformin, VML-received V. myrtillus leaf extract, VMLF-received VML, and fruit extract, VCL-received V. corymbosum leaf extract, and VCLF-received VCL and fruit extract, researchers found that according to the Bodyweight and glucose levels monitored every second week and after 8 weeks of treatment, serum glucose, insulin, and malondialdehyde measurement
* VML treated group showed no significant decrease in weight compared to a decrease in body weight in all diabetic groups in the first weeks.
* VML, VMLF, and VCLF groups demonstrated a decrease in blood glucose levels compared to the increase in the DC, PC, and VCL groups.
* Additionally, serum insulin and glucose levels at the end of the experiment were lower in VML, VMLF, and VCLF groups compared to other unimproved groups.
* More importantly, V. myrtillus extracts prevented the development of cataract compared with the DC group (P < .05).
The findings suggested that bilberry processes antioxidative stress activity against the onset of obesity and retinal degenerative disease.
Taken altogether, bilberry processed abundantly bioactive compounds may be considered a functioning remedy for the prevention and treatment of diseases associated with oxidative stress, pending to the validation of a larger sample size and multicenter human study.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
References
(1) Inhibitory activity of chokeberry, bilberry, raspberry and cranberry polyphenol-rich extract towards adipogenesis and oxidative stress in differentiated 3T3-L1 adipose cells by Kowalska K1, Olejnik A1, Szwajgier D2, Olkowicz M. (PubMed)
(2) Vaccinium Extracts as Modulators in Experimental Type 1 Diabetes by Ştefănescu Braic R1, Vari C2, Imre S3, Huţanu A4, Fogarasi E5, Todea T6, Groşan A2, Eşianu S1, Laczkó-Zöld E1, Dogaru M. (PubMed)
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