Infection is a condition caused by a harmful microbial invasion of the body tissues
Most cases of bacterial infection are treated with antibiotics. However, bacterias are very adaptable, overuse of antibiotics has been found to make them resistant to antibiotics.
Out of trillions of strains of bacteria in the world, only a few cause diseases in humans. Believe it or not, our gut contains trillion microorganisms, most of which are bacteria.
The most common symptoms of bacterial infection are redness and heat, swelling, fever, pain at the site of infection.
In severe cases, the patient may also experience symptoms of swollen lymph glands.
Most cases of bacterial infection are treated successfully if the types of bacteria that cause the infection are identified.
There are many risk factors associated with the onset of bacterial infection, people with severe chronic disease may increase the prevalence of bacterial infection, particularly in those with cirrhosis.
Dr. Deschênes M, the lead scientist at the Université de Montréal wrote, "Bacterial infection is a frequent and severe complication of cirrhosis. Cirrhotic patients admitted for gastrointestinal bleeding are at high risk of such a complication and have been targeted in trials of antibiotic prophylaxis".
And, " patients with severe cirrhosis who are admitted for gastrointestinal bleeding have a higher risk of developing a bacterial infection during their hospitalization than other cirrhotic patients".
Cranberry is an evergreen dwarf shrub, genus Vaccinium, belongings to the family Ericaceae, native to Northern America and Southern Asia. Because of its health benefits, cranberry has been cultivated in some parts of the world for commercial profit and used in traditional and herbal medicine to treat wounds, urinary disorders, diarrhea, diabetes, stomach ailments, and liver problems.
On finding a potential compound for the treatment of bacterial infection, researchers examined the effect of cranberry antibacterial activity against uropathogenic strains of Escherichia coli (UPEC).
According to the tested analysis, the whole extract showed a powerful antibacterial activity against UPEC compared to the selected fractions that presented a different behavior.
Myricetin and quercitrin demonstrated the highest decrease of E. coli biofilm formation compared with the control and other fractions.
However, other chemical constituents such as dihydro ferulic acid glucuronide, procyanidin A dimer, quercetin glucoside, myricetin, and prodelphinidin B led to a significant decrease of the surface hydrophobicity compared with the control.
In other words, all fractions in the cranberry extract worked synergistically to protect the host against the infection caused by E. coli
Based on the results, researchers said, "apart from proanthocyanidins, other compounds, mainly flavonoids, can act against E. coli biofilm formation and also modify UPEC surface hydrophobicity in vitro."
Taken altogether, cranberry may be considered a remedy for the prevention and treatment of bacterial infection, pending the confirmation of the larger sample size and multicenter human study.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Antibacterial activity of isolated phenolic compounds from cranberry (Vaccinium macrocarpon) against Escherichia coli by Rodríguez-Pérez C1, Quirantes-Piné R2, Uberos J3, Jiménez-Sánchez C1, Peña A4, Segura-Carretero A. (PubMed)
(2) In Vivo Consumption of Cranberry Exerts ex Vivo Antiadhesive Activity against FimH-Dominated Uropathogenic Escherichia coli: A Combined in Vivo, Ex Vivo, and In Vitro Study of an Extract from Vaccinium macrocarpon by Rafsanjany N1, Senker J1, Brandt S1, Dobrindt U2, Hensel A. (PubMed)
(3) Risk factors for the development of bacterial infections in hospitalized patients with cirrhosis by Deschênes M1, Villeneuve JP. (PubMed)
Saturday, September 18, 2021
Friday, September 3, 2021
Phytochemical Lycopene Inhibits the Risk of Dyslipidemia in Human Study
Antioxidants are stable atoms that inhibit the oxidation caused by reactive oxygen species.
Antioxidants also play a critical role in the prevention of the oxidative stress induced by a chain of reactions as a result of over-expression of free radicals that can only be stopped with the expression of antioxidants produced by the host or from the dietary sources.
More precisely, oxidative stress is caused by the imbalance of the ratio of free radicals and antioxidants.
Epidemiologically, over time, oxidative stress induces damage of protein, lipid, and cell DNA that lead to the incidences of chronic disease, including heart disease, RA, and cancers.
In cancer, antioxidants are molecules that process the capability to protect healthy cells against oxidative stress-induced DNA alternation.
In cardiovascular disease, antioxidants reduce the fragility and “permeability” in capillaries and prevent the clotting up of arteries due to oxidation.
In RA, antioxidant inhibits the rheumatoid joint fluid containing significant amounts of hydroxyl radical.
The overexpression of free radicals is bad. However, free radicals generated from cell metabolism may play a critical role in the synthesis of the energy of essential molecules and boosting the immune system. According to the free radical theory, over time, the damage inflicted by reactive oxygen species (ROS), can also induce skin aging.
In a healthy individual, antioxidant enzymes produced by the body are more than enough to accounter the expression of free radicals occurred in our body every day.
However, in people with a weakened immune system such as the elderly, the intake of dietary antioxidants such as supplements or fruits rich with antioxidants may be the only option to improve levels of antioxidants in the body.
Dyslipidemia is a condition with an abnormally high amount of lipids (e.g. triglycerides, cholesterol, and/or fat phospholipids) in the blood.
Lycopene is a phytochemical in the class of carotenoid, a natural pigment with no vitamin A activity found abundantly in tomatoes and other red fruits and vegetables, such as red carrots, watermelons, and papayas,
Tomatoes provide about 80% of the lycopene in the world diet. In plants, lycopene protects the host against excessive photodamage and performs various functions in photosynthesis.
On finding a potential ingredient for the prevention and treatment of diseases associated with oxidative stress, researchers examined the effects of lycopene on vascular oxidative stress and inflammation in a young healthy subject.
The study included blood collection of 18 men and 9 women with restriction of lycopene-containing foods for 1-wk (LYr), after a fasting state, and 3 h after an HFm and a low-fat meal (LFm).
Compared to the blood sample collected on pre-and post-meals following 1-wk of 80 mg/day lycopene supplementation (LYs) under continued dietary LYr in the fasting state, researchers found that
* LYs compared with LYr not only evoked a >2-fold increase in plasma lycopene but also increased plasma beta-carotene and alpha-tocopherol.
* However, LYs did not affect plasma nitrate/nitrite, a biomarker of nitric oxide, malondialdehyde, a biomarker of lipid oxidative stress, vascular- and intercellular-adhesion molecules or C-reactive protein, the biomarkers of inflammation.
In other words, HFm-induced dyslipidemic state was inhibited by LYr or LYs but did not affect the plasma malondialdehyde, C-reactive protein, or adhesion molecules.
The results suggested that 1-wk of LYs increased plasma lycopene, beta-carotene, and alpha-tocopherol do not have an effect on the plasma lipid-soluble antioxidant pool, biomarkers of vascular oxidative stress and inflammation in the fasted state as well as during dyslipidemia induced by an HFm in young healthy subjects.
In other words, plasma lycopene consumption inhibits dyslipidemia but does not affect the changes of parameters induced by an HFm in young healthy subjects in the short term.
Intake of lycopene in the form of supplements should be taken with extreme care to prevent overdose acute liver toxicity.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) The role of the antioxidants lycopene and vitamin E in the prevention of halothane-induced hepatotoxicity by Beştaş A1, Kahramanoglu M, Erhan OL, Bolat E, Ozercan I, Gürsu F, Gülcü F. (PubMed)
(2) Effect of short-term lycopene supplementation and postprandial dyslipidemia on plasma antioxidants and biomarkers of endothelial health in young, healthy individuals by Denniss SG1, Haffner TD, Kroetsch JT, Davidson SR, Rush JW, Hughson RL. (PubMed)
Antioxidants also play a critical role in the prevention of the oxidative stress induced by a chain of reactions as a result of over-expression of free radicals that can only be stopped with the expression of antioxidants produced by the host or from the dietary sources.
More precisely, oxidative stress is caused by the imbalance of the ratio of free radicals and antioxidants.
Epidemiologically, over time, oxidative stress induces damage of protein, lipid, and cell DNA that lead to the incidences of chronic disease, including heart disease, RA, and cancers.
In cancer, antioxidants are molecules that process the capability to protect healthy cells against oxidative stress-induced DNA alternation.
In cardiovascular disease, antioxidants reduce the fragility and “permeability” in capillaries and prevent the clotting up of arteries due to oxidation.
In RA, antioxidant inhibits the rheumatoid joint fluid containing significant amounts of hydroxyl radical.
The overexpression of free radicals is bad. However, free radicals generated from cell metabolism may play a critical role in the synthesis of the energy of essential molecules and boosting the immune system. According to the free radical theory, over time, the damage inflicted by reactive oxygen species (ROS), can also induce skin aging.
In a healthy individual, antioxidant enzymes produced by the body are more than enough to accounter the expression of free radicals occurred in our body every day.
However, in people with a weakened immune system such as the elderly, the intake of dietary antioxidants such as supplements or fruits rich with antioxidants may be the only option to improve levels of antioxidants in the body.
Dyslipidemia is a condition with an abnormally high amount of lipids (e.g. triglycerides, cholesterol, and/or fat phospholipids) in the blood.
Lycopene is a phytochemical in the class of carotenoid, a natural pigment with no vitamin A activity found abundantly in tomatoes and other red fruits and vegetables, such as red carrots, watermelons, and papayas,
Tomatoes provide about 80% of the lycopene in the world diet. In plants, lycopene protects the host against excessive photodamage and performs various functions in photosynthesis.
On finding a potential ingredient for the prevention and treatment of diseases associated with oxidative stress, researchers examined the effects of lycopene on vascular oxidative stress and inflammation in a young healthy subject.
The study included blood collection of 18 men and 9 women with restriction of lycopene-containing foods for 1-wk (LYr), after a fasting state, and 3 h after an HFm and a low-fat meal (LFm).
Compared to the blood sample collected on pre-and post-meals following 1-wk of 80 mg/day lycopene supplementation (LYs) under continued dietary LYr in the fasting state, researchers found that
* LYs compared with LYr not only evoked a >2-fold increase in plasma lycopene but also increased plasma beta-carotene and alpha-tocopherol.
* However, LYs did not affect plasma nitrate/nitrite, a biomarker of nitric oxide, malondialdehyde, a biomarker of lipid oxidative stress, vascular- and intercellular-adhesion molecules or C-reactive protein, the biomarkers of inflammation.
In other words, HFm-induced dyslipidemic state was inhibited by LYr or LYs but did not affect the plasma malondialdehyde, C-reactive protein, or adhesion molecules.
The results suggested that 1-wk of LYs increased plasma lycopene, beta-carotene, and alpha-tocopherol do not have an effect on the plasma lipid-soluble antioxidant pool, biomarkers of vascular oxidative stress and inflammation in the fasted state as well as during dyslipidemia induced by an HFm in young healthy subjects.
In other words, plasma lycopene consumption inhibits dyslipidemia but does not affect the changes of parameters induced by an HFm in young healthy subjects in the short term.
Intake of lycopene in the form of supplements should be taken with extreme care to prevent overdose acute liver toxicity.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) The role of the antioxidants lycopene and vitamin E in the prevention of halothane-induced hepatotoxicity by Beştaş A1, Kahramanoglu M, Erhan OL, Bolat E, Ozercan I, Gürsu F, Gülcü F. (PubMed)
(2) Effect of short-term lycopene supplementation and postprandial dyslipidemia on plasma antioxidants and biomarkers of endothelial health in young, healthy individuals by Denniss SG1, Haffner TD, Kroetsch JT, Davidson SR, Rush JW, Hughson RL. (PubMed)
Ginger, the Potent anti Metabolic Syndrome Pungent Spice, Scientists Say
Ginger may have a potential and profound effect in regulating the expression of metabolic syndrome, some scientists suggested.
Metabolic syndrome is a cluster of conditions associated with the onset of cardiovascular disease and diabetes, including fat around the waist, elevated blood pressure, high triglycerides, elevated blood sugar, and low HDL cholesterol.
Researchers suggested that people who have 3 of 5 above conditions are at substantial risk of heart disease, stroke, and type 2 diabetes.
There is no single cause of the metabolic syndrome. some conditions epidemiologically are associated with overweight or obesity, insulin resistance, inactive lifestyle, and poor diet.
According to the statistic, In the US, approximately, over 23 percent of adults have metabolic syndrome, many of them do not know they have it.
In fact, metabolic syndrome can be reversed through a healthy lifestyle choice, accompanied by weight loss.
Dr. Christos Pitsavos, the cardio team at the University of Athens and Society for Biomedical Diabetes Research, wrote, "Several epidemiologic studies and some clinical trials, it has been suggested that people with the metabolic syndrome may benefit from intensive lifestyle modifications including dietary changes and adopting a physically more active lifestyle."
"During the last decades increasing scientific evidence has emerged that protective health effects can be obtained from diets that are rich in fruits, vegetables, legumes, and whole grains, and which include fish, nuts, and low-fat dairy products".
These results clearly stated that by changing the poor diet pattern to a healthy one accompanied by moderate exercise, metabolic syndrome can be reserved.
Furthermore, a healthy lifestyle in patients with metabolic syndrome also greatly improved the reduction of body weight.
Ginger (Zingiber officinale) or ginger root, the second superfood used for thousands of years by mankind, is the genus Zingiber, belonging to the family Zingiberaceae, native to Tamil.
The root has been used in traditional and Chinese medicine to treat dyspepsia, gastroparesis, constipation, edema, difficult urination, colic, etc.
With an aim to find a natural ingredient or whole food for the treatment of metabolic syndrome, researchers assess the effects of ginger (Zingiber officinale Roscoe) on type 2 diabetes mellitus (T2DM) and/or components of the metabolic syndrome (MetS) by searching the database of medical literature.
10 studies met the inclusion criteria with a total of 490 individuals were included in the review.
Ginger showed a significant beneficial effect on glucose control and insulin sensitivity.
Ginger significantly reduced fasting blood glucose in T2DM patients (-21.24; 95% CI: -33.21, -9.26; P < 0.001) and three-month average plasma glucose concentration.
Furthermore, ginger also displayed significant effects of improvement of lipid profile.
Dr. Zhu J, the lead scientist said, in the final report "Based on the negligible side effects and obvious ameliorative effects on glucose control, insulin sensitivity, and lipid profile, ginger may be a promising adjuvant therapy for T2DM and MetS".
Moreover, in order to gain more evidence of ginger anti-metabolic syndrome effect, a study to determine the individual and concomitant effect of 6-weeks water-based exercise and oral ginger supplement on markers that have related to metabolic syndrome and systemic inflammation in obese women with breast neoplasms was conducted the University of Mazandaran.
40 women diagnosed with breast neoplasms were randomly assigned into four groups; placebo, exercise training, ginger supplement, and exercise training+ ginger supplement groups.
Participants in the ginger supplement group and the exercise training+ ginger supplement group have orally received 4 capsules, 7 days a week and for 6 weeks.
During the experiment, the ginger supplementation and the water-based exercise have resulted in a reduction of hs-CRP, IL-10 (inflammation), insulin, glucose, insulin resistance, low-density lipoprotein (LDL), triglyceride (TG); but an increase in high-density lipoprotein (HDL) and ratio HDL/LDL.
These results strongly suggested that ginger supplement plus exercise demonstrates a significant effect in reducing the fasting glucose, insulin resistance, inflammation, and lipid profile and balanced the ratio of high and low-density lipoproteins.
In other words, the water-based exercise and ginger supplement group significantly showed a larger positive effect on all outcomes, compared to the water-based exercise or ginger supplement alone groups.
The findings suggested that obese breast neoplasms survivors' metabolic syndrome and elevated inflammation were totally inhibited by the application of ginger supplement plus exercise training.
Taken altogether, ginger, the pungent spice can be considered a functional food for the prevention and treatment of metabolic syndrome accompanied by moderate exercise without inducing any adverse effects.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma ISSN 0975-6299.
Sources
(1) Effects of Ginger (Zingiber officinale Roscoe) on Type 2 Diabetes Mellitus and Components of the Metabolic Syndrome: A Systematic Review and Meta-Analysis of Randomized Controlled Trials by Zhu J1, Chen H1, Song Z1, Wang X1, Sun Z2. (PubMed)
(2) Individually and Combined Water-Based Exercise With Ginger Supplement, on Systemic Inflammation and Metabolic Syndrome Indices, Among the Obese Women With Breast Neoplasms by Karimi N1, Dabidi Roshan V1, Fathi Bayatiyani Z1. (PubMed)
(3) Diet, Exercise and Metabolic Syndrome by Christos Pitsavos,1 Demosthenes Panagiotakos,2 Michael Weinem,3 and Christodoulos Stefanadis. (PMC)
Metabolic syndrome is a cluster of conditions associated with the onset of cardiovascular disease and diabetes, including fat around the waist, elevated blood pressure, high triglycerides, elevated blood sugar, and low HDL cholesterol.
Researchers suggested that people who have 3 of 5 above conditions are at substantial risk of heart disease, stroke, and type 2 diabetes.
There is no single cause of the metabolic syndrome. some conditions epidemiologically are associated with overweight or obesity, insulin resistance, inactive lifestyle, and poor diet.
According to the statistic, In the US, approximately, over 23 percent of adults have metabolic syndrome, many of them do not know they have it.
In fact, metabolic syndrome can be reversed through a healthy lifestyle choice, accompanied by weight loss.
Dr. Christos Pitsavos, the cardio team at the University of Athens and Society for Biomedical Diabetes Research, wrote, "Several epidemiologic studies and some clinical trials, it has been suggested that people with the metabolic syndrome may benefit from intensive lifestyle modifications including dietary changes and adopting a physically more active lifestyle."
"During the last decades increasing scientific evidence has emerged that protective health effects can be obtained from diets that are rich in fruits, vegetables, legumes, and whole grains, and which include fish, nuts, and low-fat dairy products".
These results clearly stated that by changing the poor diet pattern to a healthy one accompanied by moderate exercise, metabolic syndrome can be reserved.
Furthermore, a healthy lifestyle in patients with metabolic syndrome also greatly improved the reduction of body weight.
Ginger (Zingiber officinale) or ginger root, the second superfood used for thousands of years by mankind, is the genus Zingiber, belonging to the family Zingiberaceae, native to Tamil.
The root has been used in traditional and Chinese medicine to treat dyspepsia, gastroparesis, constipation, edema, difficult urination, colic, etc.
With an aim to find a natural ingredient or whole food for the treatment of metabolic syndrome, researchers assess the effects of ginger (Zingiber officinale Roscoe) on type 2 diabetes mellitus (T2DM) and/or components of the metabolic syndrome (MetS) by searching the database of medical literature.
10 studies met the inclusion criteria with a total of 490 individuals were included in the review.
Ginger showed a significant beneficial effect on glucose control and insulin sensitivity.
Ginger significantly reduced fasting blood glucose in T2DM patients (-21.24; 95% CI: -33.21, -9.26; P < 0.001) and three-month average plasma glucose concentration.
Furthermore, ginger also displayed significant effects of improvement of lipid profile.
Dr. Zhu J, the lead scientist said, in the final report "Based on the negligible side effects and obvious ameliorative effects on glucose control, insulin sensitivity, and lipid profile, ginger may be a promising adjuvant therapy for T2DM and MetS".
Moreover, in order to gain more evidence of ginger anti-metabolic syndrome effect, a study to determine the individual and concomitant effect of 6-weeks water-based exercise and oral ginger supplement on markers that have related to metabolic syndrome and systemic inflammation in obese women with breast neoplasms was conducted the University of Mazandaran.
40 women diagnosed with breast neoplasms were randomly assigned into four groups; placebo, exercise training, ginger supplement, and exercise training+ ginger supplement groups.
Participants in the ginger supplement group and the exercise training+ ginger supplement group have orally received 4 capsules, 7 days a week and for 6 weeks.
During the experiment, the ginger supplementation and the water-based exercise have resulted in a reduction of hs-CRP, IL-10 (inflammation), insulin, glucose, insulin resistance, low-density lipoprotein (LDL), triglyceride (TG); but an increase in high-density lipoprotein (HDL) and ratio HDL/LDL.
These results strongly suggested that ginger supplement plus exercise demonstrates a significant effect in reducing the fasting glucose, insulin resistance, inflammation, and lipid profile and balanced the ratio of high and low-density lipoproteins.
In other words, the water-based exercise and ginger supplement group significantly showed a larger positive effect on all outcomes, compared to the water-based exercise or ginger supplement alone groups.
The findings suggested that obese breast neoplasms survivors' metabolic syndrome and elevated inflammation were totally inhibited by the application of ginger supplement plus exercise training.
Taken altogether, ginger, the pungent spice can be considered a functional food for the prevention and treatment of metabolic syndrome accompanied by moderate exercise without inducing any adverse effects.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma ISSN 0975-6299.
Sources
(1) Effects of Ginger (Zingiber officinale Roscoe) on Type 2 Diabetes Mellitus and Components of the Metabolic Syndrome: A Systematic Review and Meta-Analysis of Randomized Controlled Trials by Zhu J1, Chen H1, Song Z1, Wang X1, Sun Z2. (PubMed)
(2) Individually and Combined Water-Based Exercise With Ginger Supplement, on Systemic Inflammation and Metabolic Syndrome Indices, Among the Obese Women With Breast Neoplasms by Karimi N1, Dabidi Roshan V1, Fathi Bayatiyani Z1. (PubMed)
(3) Diet, Exercise and Metabolic Syndrome by Christos Pitsavos,1 Demosthenes Panagiotakos,2 Michael Weinem,3 and Christodoulos Stefanadis. (PMC)
Saturday, August 28, 2021
Berry Extract Inhibits β-Amyloid Aggregation
Amyloid beta (Aβ or Abeta) is the main component of the amyloid plaques that cause the gradual death of neurons, leading to the onset of Alzheimer's disease.
Alzheimer's disease is a common form of dementia or neurodegenerative disease found in the elderly.
Alzheimer's disease is a type of dementia correlated with major reductions of neurons to the respective target areas, named after German physician Alois Alzheimer.
According to the statistics, the disease is most prevalent in the elderly. Approximately 5.7 million Americans of all ages are living with Alzheimer's. 15.9 million family caregivers provide an estimated 18.2 billion hours and $230 billion to people with dementia worldwide.
Alzheimer's disease is caused by a combination of genetic, lifestyle, and environmental factors that affect the neurons of the brain over time. However, less than 10% of patients with AD are associated with a genetic preposition. Patients with such mutated genes on chromosomes 21, 14, and 1are virtually guaranteed to develop the disease.
More precisely, Alzheimer's disease is caused by the gradual loss of neuron functioning that usually starts with the early symptom of the difficulty of remembering recent events and worsens over time.
Alzheimer's destroys brain cells, causing cognitive modalities severe enough to affect language communication, memory, lifelong hobbies, or social life. Alzheimer's gets worse over time, and it is fatal.
Dementia is a group of neurodegenerative diseases caused by a decline in mental ability in the older population that is severe enough to interfere with daily life, such as memory loss.
Compared to dementia, neurological disorders are a class of brain disease associated with reduced function of the brain, depending on the region of the neurons that were affected.
Dr. Rudolph E. Tanzi said, "The inheritance of AD exhibits a dichotomous pattern. On one hand, rare mutations in APP, PSEN1, and PSEN2 virtually guarantee early-onset (<60 years) familial AD, which represents ∼5% of AD. On the other hand, common gene polymorphisms, such as the ε4 and ε2 variants of the APOE gene, can influence susceptibility for ∼50% of the common late-onset AD".
And, " These four genes account for 30%–50% of the inheritability of AD".
Cranberry is an evergreen dwarf shrub, genus Vaccinium, belongings to the family Ericaceae, native to Northern America and Southern Asia. Because of its health benefits, cranberry has been cultivated in some parts of the world for commercial profit and used in traditional and herbal medicine to treat wounds, urinary disorders, diarrhea, diabetes, stomach ailments, and liver problems.
On finding a potential compound for the treatment of neurodegenerative disorders, researchers examined the effect of cranberry extract (CE) on the Alzheimer's disease (AD)associated with the aggregation and toxicity of proteins β-amyloid (Aβ).
The study is to compare the effects of berry crude extracts (CE) that yield anthocyanins-free (ACF) and anthocyanins-enriched (ACE) extracts.
According to the tested analysis, the berry ACEs (at 100 μg/mL) showed superior free radical scavenging, reactive carbonyl species trapping, and anti-glycation effects, compared to ACFs.
Furthermore, the berry ACEs at a dose of 100 μg/mL inhibited both thermal- and reactive carbonyl species (methylglyoxal; MGO)-induced Aβ fibrillation associated with the production of pro-inflammatory cytokines.
In BV-2 microglia, the berry ACEs at a dose of 20 μg/mL reduced H₂O₂-induced reactive oxygen species production and lipopolysaccharide-induced nitric oxide species.
Based on the findings, researchers said, "The free radical scavenging, reactive carbonyl trapping, anti-glycation, anti-Aβ fibrillation, and microglial neuroprotective effects of these berry extracts warrant further in vivo studies to evaluate their potential neuroprotective effects against AD.".
Taken altogether, berries including cranberry processed abundantly anthocyanins may be considered remedies for the prevention of β-Amyloid Aggregation against the onset of AD, pending the confirmation of the larger sample size and multicenter human study.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You. How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Evaluation of Polyphenol Anthocyanin-Enriched Extracts of Blackberry, Black Raspberry, Blueberry, Cranberry, Red Raspberry, and Strawberry for Free Radical Scavenging, Reactive Carbonyl Species Trapping, Anti-Glycation, Anti-β-Amyloid Aggregation, and Microglial Neuroprotective Effects by Ma H1,2,3, Johnson SL4,5, Liu W6, DaSilva NA7,8, Meschwitz S9, Dain JA10, Seeram NP. (PubMed)
(2) The Genetics of Alzheimer Disease by Rudolph E. Tanzi. (NCBI)
Alzheimer's disease is a common form of dementia or neurodegenerative disease found in the elderly.
Alzheimer's disease is a type of dementia correlated with major reductions of neurons to the respective target areas, named after German physician Alois Alzheimer.
According to the statistics, the disease is most prevalent in the elderly. Approximately 5.7 million Americans of all ages are living with Alzheimer's. 15.9 million family caregivers provide an estimated 18.2 billion hours and $230 billion to people with dementia worldwide.
Alzheimer's disease is caused by a combination of genetic, lifestyle, and environmental factors that affect the neurons of the brain over time. However, less than 10% of patients with AD are associated with a genetic preposition. Patients with such mutated genes on chromosomes 21, 14, and 1are virtually guaranteed to develop the disease.
More precisely, Alzheimer's disease is caused by the gradual loss of neuron functioning that usually starts with the early symptom of the difficulty of remembering recent events and worsens over time.
Alzheimer's destroys brain cells, causing cognitive modalities severe enough to affect language communication, memory, lifelong hobbies, or social life. Alzheimer's gets worse over time, and it is fatal.
Dementia is a group of neurodegenerative diseases caused by a decline in mental ability in the older population that is severe enough to interfere with daily life, such as memory loss.
Compared to dementia, neurological disorders are a class of brain disease associated with reduced function of the brain, depending on the region of the neurons that were affected.
Dr. Rudolph E. Tanzi said, "The inheritance of AD exhibits a dichotomous pattern. On one hand, rare mutations in APP, PSEN1, and PSEN2 virtually guarantee early-onset (<60 years) familial AD, which represents ∼5% of AD. On the other hand, common gene polymorphisms, such as the ε4 and ε2 variants of the APOE gene, can influence susceptibility for ∼50% of the common late-onset AD".
And, " These four genes account for 30%–50% of the inheritability of AD".
Cranberry is an evergreen dwarf shrub, genus Vaccinium, belongings to the family Ericaceae, native to Northern America and Southern Asia. Because of its health benefits, cranberry has been cultivated in some parts of the world for commercial profit and used in traditional and herbal medicine to treat wounds, urinary disorders, diarrhea, diabetes, stomach ailments, and liver problems.
On finding a potential compound for the treatment of neurodegenerative disorders, researchers examined the effect of cranberry extract (CE) on the Alzheimer's disease (AD)associated with the aggregation and toxicity of proteins β-amyloid (Aβ).
The study is to compare the effects of berry crude extracts (CE) that yield anthocyanins-free (ACF) and anthocyanins-enriched (ACE) extracts.
According to the tested analysis, the berry ACEs (at 100 μg/mL) showed superior free radical scavenging, reactive carbonyl species trapping, and anti-glycation effects, compared to ACFs.
Furthermore, the berry ACEs at a dose of 100 μg/mL inhibited both thermal- and reactive carbonyl species (methylglyoxal; MGO)-induced Aβ fibrillation associated with the production of pro-inflammatory cytokines.
In BV-2 microglia, the berry ACEs at a dose of 20 μg/mL reduced H₂O₂-induced reactive oxygen species production and lipopolysaccharide-induced nitric oxide species.
Based on the findings, researchers said, "The free radical scavenging, reactive carbonyl trapping, anti-glycation, anti-Aβ fibrillation, and microglial neuroprotective effects of these berry extracts warrant further in vivo studies to evaluate their potential neuroprotective effects against AD.".
Taken altogether, berries including cranberry processed abundantly anthocyanins may be considered remedies for the prevention of β-Amyloid Aggregation against the onset of AD, pending the confirmation of the larger sample size and multicenter human study.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You. How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Evaluation of Polyphenol Anthocyanin-Enriched Extracts of Blackberry, Black Raspberry, Blueberry, Cranberry, Red Raspberry, and Strawberry for Free Radical Scavenging, Reactive Carbonyl Species Trapping, Anti-Glycation, Anti-β-Amyloid Aggregation, and Microglial Neuroprotective Effects by Ma H1,2,3, Johnson SL4,5, Liu W6, DaSilva NA7,8, Meschwitz S9, Dain JA10, Seeram NP. (PubMed)
(2) The Genetics of Alzheimer Disease by Rudolph E. Tanzi. (NCBI)
Tuesday, August 24, 2021
11 Health Benefits of Phytochemical Tocopherols
Tocopherols are phytochemicals of which many have vitamin E activity, belonging to the group of Lipids, found abundantly in butter, egg yolk, milk fat, some vegetable, and seed or nut oils, etc.
Health benefits
1. Antioxidative, anti-inflammatory, and anticarcinogenic activities
In the examination of the inhibition of inflammation as well as of cancer formation and growth in the lung and colon in animal models., using a-tocopherol mixture that is rich in gamma-T (gamma-TmT, which contains 57%gamma-T), found that when given in the diet at 0.3%, gamma-TmT inhibited chemically induced lung tumorigenesis in the A/J mice as well as the growth of human lung cancer cell H1299 xenograft tumors. gamma-TmT also decreased the levels of 8-hydroxydeoxyguanosine, gamma-H2AX, and nitrotyrosine in tumors. More evident anti-inflammatory and cancer preventive activities of dietary gamma-TmT were demonstrated in mice treated with azoxymethane and dextran sulfate sodium. These results demonstrate the antioxidative, anti-inflammatory, and anticarcinogenic activities of tocopherols, according to "Inhibition of inflammation and carcinogenesis in the lung and colon by tocopherols" by Yang CS, Lu G, Ju J, Li GX.(1)
2. Cancer prevention
The study of the cancer-preventive activities of tocopherols and tocotrienols, indicated that a gamma-tocopherol-rich mixture of tocopherols inhibits colon, prostate, mammary, and lung tumorigenesis in animal models, suggesting that this mixture may have a high potential for applications in the prevention of human cancer. In this review, we discuss biochemical properties of tocopherols, results of possible cancer-preventive effects in humans and animal models, and possible mechanisms involved in the inhibition of carcinogenesis. Based on this information, we propose that a gamma-tocopherol-rich mixture of tocopherols is a very promising cancer-preventive agent and warrants extensive future research, according to "Cancer-preventive activities of tocopherols and tocotrienols" by Ju J, Picinich SC, Yang Z, Zhao Y, Suh N, Kong AN, Yang CS.(2)
3. Bone formation
In the investigation of the antioxidant and anti-inflammatory properties of Alpha- and gamma-tocopherol, the two predominant isomers of vitamin E and their effects on bone metabolism, found that gamma-tocopherol may uncouple bone turnover, resulting in more bone formation than resorption. Vitamin E supplements in the form of alpha-tocopherol suppress serum gamma-tocopherol levels and may have negative effects on bone formation. Further research is needed to investigate the potential anabolic effect of gamma-tocopherol from food sources on bone, according to "Effects of vitamin E on bone turnover markers among US postmenopausal women" by Hamidi MS, Corey PN, Cheung AM.(3)
4. Liver fibrosis
In the study of Antiproliferative and proapoptotic effects of tocopherol and tocol on activated hepatic stellate cells, found that significant cell detachment was also observed in δ-tocopherol- and tocol-treated HSCs. Decreased protein expressions of α-smooth muscle actin and β1 integrin were observed in a dose-dependent manner. These results indicate that δ-tocopherol and tocol induce anoikis in activated HSCs, according to "Antiproliferative and proapoptotic effects of tocopherol and tocol on activated hepatic stellate cells" by Yamaguchi N, Mezaki Y, Miura M, Imai K, Morii M, Hebiguchi T, Yoshikawa K.(4)
5. Antioxidant and Antidiabetic Activities
In the determination of the antioxidant and antidiabetic activities of proximate composition, amino acids, fatty acids, tocopherols, sterols, glucosinolate and phenolic content in extracts, found that all examined extracts were prominently rich in phenolics and glucosinates, and they showed potent antidiabetic and antihemolytic activity. The present study could be helpful in developing medicinal preparations for the treatment of diabetes and related symptoms, according to "Compositional Studies: Antioxidant and Antidiabetic Activities of Capparis decidua (Forsk.) Edgew" by Zia-Ul-Haq M, Cavar S, Qayum M, Imran I, de Feo V.(5)
6. Breast cancer
in the investigation of the breast cancer effect of vitamin E, consisting of eight different variants: α-, β-, γ-, and δ-tocopherols (saturated phytyl tail) and α-, β-, γ-, and δ-tocotrienols (unsaturated phytyl tail), indicated that γ-tocopherol, and more recently δ-tocopherol, have shown greater ability to reduce inflammation, cell proliferation, and tumor burden. Recent results have shown that γ-enriched mixed tocopherols inhibit the development of mammary hyperplasia and tumorigenesis in animal models, according to "Chemopreventive Activity of Vitamin E in Breast Cancer: A Focus on γ- and δ-Tocopherol" by Smolarek AK, Suh N.(6)
7. Colon cancer
In the investigation of the effects of both alpha and gamma-tocopherol on the expression of PPARgamma mRNA and protein in SW 480 colon cancer cell lines and measurement of the intracellular concentrations of vitamin E in SW 480 colon cancer cell lines, found that both alpha and gamma-tocopherol can upregulate the expression of PPARgamma which is considered an important molecular target for colon cancer chemoprevention, according to "Gamma (gamma) tocopherol upregulates peroxisome proliferator-activated receptor (PPAR) gamma (gamma) expression in SW 480 human colon cancer cell lines" by Campbell SE, Stone WL, Whaley SG, Qui M, Krishnan K.(7)
8. Antioxidant defense
in the study of salmon, a rich source of marine n-3 fatty acids, which may increase oxidative stress and, in turn, and its affect the antioxidant defense system in blood plasma and erythrocytes of pregnant women, found that besides, a concomitant increase in selenium and glutathione concentration, as well as glutathione peroxidase and reductase activities, were detected as the pregnancy progressed. However, tocopherols, retinol, β-carotene, and coenzyme Q(10) decreased in late pregnancy. Collectively, our findings lead to the hypothesis that increased farmed salmon intake may increase antioxidant defenses during pregnancy, according to "Does Consumption of Two Portions of Salmon Per Week Enhance the Antioxidant Defense System in Pregnant Women?" by García-Rodríguez CE, D Mesa M, Olza J, Vlachava M, Kremmyda LS, Diaper ND, Noakes PS, Miles EA, Ramírez-Tortosa MC, Liaset B, Frøyland L, Rossary A, Farges MC, Vasson MP, Aguilera CM, Helmersson-Karlqvist J, Godfrey KM, Calder PC, Basu S, Gil A.(8)
9. The antioxidant and anti-inflammatory activities
In the investigation of the antioxidant and anti-inflammatory actions of tocopherols in mice and determination of whether the nuclear factor (erythroid-derived 2)-like 2 (Nrf2) is involved in these activities, indicated that the antioxidant and anti-inflammatory activities of γ-TmT in the colon are mostly due to the direct action of tocopherols in trapping reactive oxygen and nitrogen species, independent of the antioxidant enzymes and anti-inflammatory proteins that are regulated by Nrf2; however, Nrf2 knockout appears to affect the serum levels of tocopherol metabolites, according to "The antioxidant and anti-inflammatory activities of tocopherols are independent of Nrf2 in mice" by Li G, Lee MJ, Liu AB, Yang Z, Lin Y, Shih WJ, Yang CS.(9)
10. Cognitive effects
In the examination of the relation of all plasma vitamin E forms and markers of vitamin E damage (α-tocopheryl quinone, 5-nitro-γ-tocopherol) to mild cognitive impairment (MCI) and Alzheimer's disease (AD). Within the AddNeuroMed-Project, plasma tocopherols, tocotrienols, α-tocopheryl quinone, and 5-nitro-γ-tocopherol were assessed in 168 AD cases, 166 MCI, and 187 cognitively normal (CN) people, found that compared with cognitively normal subjects, AD and MCI had lower levels of total tocopherols, total tocotrienols, and total vitamin E. In multivariable-polytomous-logistic regression analysis, both MCI and AD cases had 85% lower odds to be in the highest tertile of total tocopherols and total vitamin E, and they were, respectively, 92% and 94% less likely to be in the highest tertile of total tocotrienols than the lowest tertile. Further, both disorders were associated with increased vitamin E damage. Low plasma tocopherols and tocotrienols levels are associated with increased odds of MCI and AD, according to "Tocopherols and tocotrienols plasma levels are associated with cognitive impairment" by Mangialasche F, Xu W, Kivipelto M, Costanzi E, Ercolani S, Pigliautile M, Cecchetti R, Baglioni M, Simmons A, Soininen H, Tsolaki M, Kloszewska I, Vellas B, Lovestone S, Mecocci P; AddNeuroMed Consortium. (10)
11. Renal effects
In the examination of whether γ-tocotrienol (GT3) protects against mitochondrial dysfunction and renal proximal tubular cell (RPTC) injury caused by oxidants, showed that report demonstrating the protective effects of GT3 against RPTC injury by 1) decreasing the production of ROS, 2) improving mitochondrial respiration, coupling, ΔΨ(m), and F₀F₁-ATPase function, 3) maintaining ATP levels, and 4) preventing RPTC lysis. Our data suggest that GT3 is superior to AT in protecting RPTCs against oxidant injury and may prove therapeutically valuable for preventing renal injury associated with oxidative stress, according to "γ-Tocotrienol protects against mitochondrial dysfunction and renal cell death" by Nowak G, Bakajsova D, Hayes C, Hauer-Jensen M, Compadre CM.(11)
12. Etc.
Chinese Secrets To Fatty Liver And Obesity Reversal
Use The Revolutionary Findings To Achieve
Optimal Health And Loose Weight
Back to Popular Herbs http://kylejnorton.blogspot.ca/p/popular-herbs.html
Back to Kyle J. Norton Home page http://kylejnorton.blogspot.ca
Sources
(1) http://www.ncbi.nlm.nih.gov/pubmed/20716280
(2) http://www.ncbi.nlm.nih.gov/pubmed/19748925
(3) http://www.ncbi.nlm.nih.gov/pubmed/22308007
(4) http://www.ncbi.nlm.nih.gov/pubmed/22293208
(5) http://www.mdpi.com/1422-0067/12/12/8846/
(6) http://www.ncbi.nlm.nih.gov/pubmed/22254089
(7) http://www.ncbi.nlm.nih.gov/pubmed/14521714
(8) http://www.ncbi.nlm.nih.gov/pubmed/22229304
(9) http://www.ncbi.nlm.nih.gov/pubmed/22226829
(10) http://www.ncbi.nlm.nih.gov/pubmed/22192241
(11) http://www.ncbi.nlm.nih.gov/pubmed/22040679
Health benefits
1. Antioxidative, anti-inflammatory, and anticarcinogenic activities
In the examination of the inhibition of inflammation as well as of cancer formation and growth in the lung and colon in animal models., using a-tocopherol mixture that is rich in gamma-T (gamma-TmT, which contains 57%gamma-T), found that when given in the diet at 0.3%, gamma-TmT inhibited chemically induced lung tumorigenesis in the A/J mice as well as the growth of human lung cancer cell H1299 xenograft tumors. gamma-TmT also decreased the levels of 8-hydroxydeoxyguanosine, gamma-H2AX, and nitrotyrosine in tumors. More evident anti-inflammatory and cancer preventive activities of dietary gamma-TmT were demonstrated in mice treated with azoxymethane and dextran sulfate sodium. These results demonstrate the antioxidative, anti-inflammatory, and anticarcinogenic activities of tocopherols, according to "Inhibition of inflammation and carcinogenesis in the lung and colon by tocopherols" by Yang CS, Lu G, Ju J, Li GX.(1)
2. Cancer prevention
The study of the cancer-preventive activities of tocopherols and tocotrienols, indicated that a gamma-tocopherol-rich mixture of tocopherols inhibits colon, prostate, mammary, and lung tumorigenesis in animal models, suggesting that this mixture may have a high potential for applications in the prevention of human cancer. In this review, we discuss biochemical properties of tocopherols, results of possible cancer-preventive effects in humans and animal models, and possible mechanisms involved in the inhibition of carcinogenesis. Based on this information, we propose that a gamma-tocopherol-rich mixture of tocopherols is a very promising cancer-preventive agent and warrants extensive future research, according to "Cancer-preventive activities of tocopherols and tocotrienols" by Ju J, Picinich SC, Yang Z, Zhao Y, Suh N, Kong AN, Yang CS.(2)
3. Bone formation
In the investigation of the antioxidant and anti-inflammatory properties of Alpha- and gamma-tocopherol, the two predominant isomers of vitamin E and their effects on bone metabolism, found that gamma-tocopherol may uncouple bone turnover, resulting in more bone formation than resorption. Vitamin E supplements in the form of alpha-tocopherol suppress serum gamma-tocopherol levels and may have negative effects on bone formation. Further research is needed to investigate the potential anabolic effect of gamma-tocopherol from food sources on bone, according to "Effects of vitamin E on bone turnover markers among US postmenopausal women" by Hamidi MS, Corey PN, Cheung AM.(3)
4. Liver fibrosis
In the study of Antiproliferative and proapoptotic effects of tocopherol and tocol on activated hepatic stellate cells, found that significant cell detachment was also observed in δ-tocopherol- and tocol-treated HSCs. Decreased protein expressions of α-smooth muscle actin and β1 integrin were observed in a dose-dependent manner. These results indicate that δ-tocopherol and tocol induce anoikis in activated HSCs, according to "Antiproliferative and proapoptotic effects of tocopherol and tocol on activated hepatic stellate cells" by Yamaguchi N, Mezaki Y, Miura M, Imai K, Morii M, Hebiguchi T, Yoshikawa K.(4)
5. Antioxidant and Antidiabetic Activities
In the determination of the antioxidant and antidiabetic activities of proximate composition, amino acids, fatty acids, tocopherols, sterols, glucosinolate and phenolic content in extracts, found that all examined extracts were prominently rich in phenolics and glucosinates, and they showed potent antidiabetic and antihemolytic activity. The present study could be helpful in developing medicinal preparations for the treatment of diabetes and related symptoms, according to "Compositional Studies: Antioxidant and Antidiabetic Activities of Capparis decidua (Forsk.) Edgew" by Zia-Ul-Haq M, Cavar S, Qayum M, Imran I, de Feo V.(5)
6. Breast cancer
in the investigation of the breast cancer effect of vitamin E, consisting of eight different variants: α-, β-, γ-, and δ-tocopherols (saturated phytyl tail) and α-, β-, γ-, and δ-tocotrienols (unsaturated phytyl tail), indicated that γ-tocopherol, and more recently δ-tocopherol, have shown greater ability to reduce inflammation, cell proliferation, and tumor burden. Recent results have shown that γ-enriched mixed tocopherols inhibit the development of mammary hyperplasia and tumorigenesis in animal models, according to "Chemopreventive Activity of Vitamin E in Breast Cancer: A Focus on γ- and δ-Tocopherol" by Smolarek AK, Suh N.(6)
7. Colon cancer
In the investigation of the effects of both alpha and gamma-tocopherol on the expression of PPARgamma mRNA and protein in SW 480 colon cancer cell lines and measurement of the intracellular concentrations of vitamin E in SW 480 colon cancer cell lines, found that both alpha and gamma-tocopherol can upregulate the expression of PPARgamma which is considered an important molecular target for colon cancer chemoprevention, according to "Gamma (gamma) tocopherol upregulates peroxisome proliferator-activated receptor (PPAR) gamma (gamma) expression in SW 480 human colon cancer cell lines" by Campbell SE, Stone WL, Whaley SG, Qui M, Krishnan K.(7)
8. Antioxidant defense
in the study of salmon, a rich source of marine n-3 fatty acids, which may increase oxidative stress and, in turn, and its affect the antioxidant defense system in blood plasma and erythrocytes of pregnant women, found that besides, a concomitant increase in selenium and glutathione concentration, as well as glutathione peroxidase and reductase activities, were detected as the pregnancy progressed. However, tocopherols, retinol, β-carotene, and coenzyme Q(10) decreased in late pregnancy. Collectively, our findings lead to the hypothesis that increased farmed salmon intake may increase antioxidant defenses during pregnancy, according to "Does Consumption of Two Portions of Salmon Per Week Enhance the Antioxidant Defense System in Pregnant Women?" by García-Rodríguez CE, D Mesa M, Olza J, Vlachava M, Kremmyda LS, Diaper ND, Noakes PS, Miles EA, Ramírez-Tortosa MC, Liaset B, Frøyland L, Rossary A, Farges MC, Vasson MP, Aguilera CM, Helmersson-Karlqvist J, Godfrey KM, Calder PC, Basu S, Gil A.(8)
9. The antioxidant and anti-inflammatory activities
In the investigation of the antioxidant and anti-inflammatory actions of tocopherols in mice and determination of whether the nuclear factor (erythroid-derived 2)-like 2 (Nrf2) is involved in these activities, indicated that the antioxidant and anti-inflammatory activities of γ-TmT in the colon are mostly due to the direct action of tocopherols in trapping reactive oxygen and nitrogen species, independent of the antioxidant enzymes and anti-inflammatory proteins that are regulated by Nrf2; however, Nrf2 knockout appears to affect the serum levels of tocopherol metabolites, according to "The antioxidant and anti-inflammatory activities of tocopherols are independent of Nrf2 in mice" by Li G, Lee MJ, Liu AB, Yang Z, Lin Y, Shih WJ, Yang CS.(9)
10. Cognitive effects
In the examination of the relation of all plasma vitamin E forms and markers of vitamin E damage (α-tocopheryl quinone, 5-nitro-γ-tocopherol) to mild cognitive impairment (MCI) and Alzheimer's disease (AD). Within the AddNeuroMed-Project, plasma tocopherols, tocotrienols, α-tocopheryl quinone, and 5-nitro-γ-tocopherol were assessed in 168 AD cases, 166 MCI, and 187 cognitively normal (CN) people, found that compared with cognitively normal subjects, AD and MCI had lower levels of total tocopherols, total tocotrienols, and total vitamin E. In multivariable-polytomous-logistic regression analysis, both MCI and AD cases had 85% lower odds to be in the highest tertile of total tocopherols and total vitamin E, and they were, respectively, 92% and 94% less likely to be in the highest tertile of total tocotrienols than the lowest tertile. Further, both disorders were associated with increased vitamin E damage. Low plasma tocopherols and tocotrienols levels are associated with increased odds of MCI and AD, according to "Tocopherols and tocotrienols plasma levels are associated with cognitive impairment" by Mangialasche F, Xu W, Kivipelto M, Costanzi E, Ercolani S, Pigliautile M, Cecchetti R, Baglioni M, Simmons A, Soininen H, Tsolaki M, Kloszewska I, Vellas B, Lovestone S, Mecocci P; AddNeuroMed Consortium. (10)
11. Renal effects
In the examination of whether γ-tocotrienol (GT3) protects against mitochondrial dysfunction and renal proximal tubular cell (RPTC) injury caused by oxidants, showed that report demonstrating the protective effects of GT3 against RPTC injury by 1) decreasing the production of ROS, 2) improving mitochondrial respiration, coupling, ΔΨ(m), and F₀F₁-ATPase function, 3) maintaining ATP levels, and 4) preventing RPTC lysis. Our data suggest that GT3 is superior to AT in protecting RPTCs against oxidant injury and may prove therapeutically valuable for preventing renal injury associated with oxidative stress, according to "γ-Tocotrienol protects against mitochondrial dysfunction and renal cell death" by Nowak G, Bakajsova D, Hayes C, Hauer-Jensen M, Compadre CM.(11)
12. Etc.
Chinese Secrets To Fatty Liver And Obesity Reversal
Use The Revolutionary Findings To Achieve
Optimal Health And Loose Weight
Back to Popular Herbs http://kylejnorton.blogspot.ca/p/popular-herbs.html
Back to Kyle J. Norton Home page http://kylejnorton.blogspot.ca
Sources
(1) http://www.ncbi.nlm.nih.gov/pubmed/20716280
(2) http://www.ncbi.nlm.nih.gov/pubmed/19748925
(3) http://www.ncbi.nlm.nih.gov/pubmed/22308007
(4) http://www.ncbi.nlm.nih.gov/pubmed/22293208
(5) http://www.mdpi.com/1422-0067/12/12/8846/
(6) http://www.ncbi.nlm.nih.gov/pubmed/22254089
(7) http://www.ncbi.nlm.nih.gov/pubmed/14521714
(8) http://www.ncbi.nlm.nih.gov/pubmed/22229304
(9) http://www.ncbi.nlm.nih.gov/pubmed/22226829
(10) http://www.ncbi.nlm.nih.gov/pubmed/22192241
(11) http://www.ncbi.nlm.nih.gov/pubmed/22040679
Fennel, The Potent Food That Processes Cyto-protection and Antitumor Activity
Fennel may have a potential and positive effect that induces cytoprotection and antitumor activity against cancer expression, scientists suggested.
The results of fennel efficacy were reported by several respectable institutes including the National Cancer Institute and the National Institute of Health.
Fennel (Foeniculum vulgare) is a plant species of the genus, belongings to Apiaceae (Umbelliferae), native to the Mediterranean, used in traditional and herbal medicine as warming, carminative, antispasmodic, antidepressant agent and to stimulate the appetite, ease indigestion, soothe coughing, reduce intestinal spasms, to regulate the menstrual cycle and relieve PMS,...
Nutrients
1. Carbohydrates
2. Fiber
3. Protein
4. Thiamine (Vitamin B1)
5. Riboflavin (Vitamin B2)
6. Niacin (Vitamin B3)
7. Pantothenic acid (B5)
8. Vitamin B6
9. Folate (Vitamin B9)
10. Vitamin C
11. Calcium
12. Copper
13. Iron
14. Magnesium
15. Molybdenum
16. Phosphorus
17. Potassium
18. Zinc
In the study to evaluate the efficacy of fennel seed methanolic extract (FSME) for its antioxidant, cytotoxic, and antitumor activities and for its capacity to serve as a nontoxic radioprotector in Swiss albino mice through injection of FSME, 100 mg/kg intraperitoneally into mice bearing EAC before exposed to three 2-Gy doses of gamma irradiation, researchers found at after 30 days, the application exerted a strong effect at the C50 (mean standard deviation 50% inhibitory concentrations) at a dose of 50 μg/mL for the MCF7 breast cancer cell line and 48 μg/mL for the Hepg-2 liver cancer cell line.
The treatment group also displayed a decreased level of MDA and improved natural antioxidants produced by the tissues of the host compared to the elevation of MDA and significantly reduced levels of catalase and GSH contents.
These results suggested that fennel seed methanolic extract (FSME) inhibited the overproduction of ROS caused by ingestion of doses of gamma irradiation through its anioxidants and enhanced antioxidants production of the mice tissue via the ratio of ROS and Antioxidants.
In other words, application of the fennel extract may have a potential in
* Reduced oxidative stress and protected mouse cells from damage caused by reactive oxygen species.
* Improved natural antioxidants and the oxidative stability of fatty foods during storage.
* Exhibited an antitumor effect by modulating lipid peroxidation and augmenting the antioxidant defense system in EAC-bearing mice with or without exposure to radiation.
Further illustration of the effect of herbal medicine in treatment of cancers and examine the cytoprotective effects, researchers at the National Institute of Health conducted a comparison of five herbal supplements, designated FB, FM, PP, HF, and FBL101, which contain different combinations of various natural herbs such as licorice, black cohosh, Dong Quai, false unicorn and vitex berry root against mice bearing CWR22R and PC3 prostate cancer xenografts.
According to the results of experiment,
* All herbal medicine, FB, FM, PP, HF, and FBL101 inhibited PC3 tumor growth by 53%, 75%, 80%, 81%, and 87%, respectively.
* In CWR22R tumors, applications of supplements exerted a similar effect in suppressing the cancer cells.
* All applications did not show inhibitory activity against levels of testosterone in compared to untreated mice. However, supplements PP and FBL101 exerted significantly reduced VEGF levels, a potent angiogenic factor with function in stimulated production of new blood vessels to ensure cell proliferation, in PC3 and CWR22R tumors.
* Intratumoral microvessel density was decreased in PC3 tumors treated with all five supplements but only in CWR22R tumors treated with HF.
Dr. Ng SS, the lead author said, "herbal supplements containing the aforementioned extracts inhibit the growth of prostate tumor xenografts, possibly in part by antiangiogenic mechanisms".
The above differentiation was supported by the Quaid-i-Azam University in the analysis of the antibacterial potential of some medicinal plants against multi-drug resistant (MDR) pathogens and anticancer effect against MCF-7 cell line.
According to the results of the report, the application of Ethanol extract of Foeniculum vulgare exhibited significant inhibition of cancer cells proliferation and induction of cancer cell apoptosis and reduction of growth of Klebsiella pneumonia, Serratia marcescens, and Methicillin-resistant S. aureus. Pseudomonas aeruginosa
Taken together, fennel and its extracts may be used as a functional food in the exertion of cytoprotection and antitumor activity.
For More information on yoga lessons tailor to a complete well being for women, please visit: YOGA FOR WOMEN
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Home page http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrients, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.
Sources
(1) Antioxidant and anticarcinogenic effects of methanolic extract and volatile oil of fennel seeds (Foeniculum vulgare) by Mohamad RH1, El-Bastawesy AM, Abdel-Monem MG, Noor AM, Al-Mehdar HA, Sharawy SM, El-Merzabani MM.(PubMed)
(2) Antitumor activity of herbal supplements in human prostate cancer xenografts implanted in immunodeficient mice by Ng SS1, Figg WD.(PubMed)
(3) Study of anticancer and antibacterial activities of Foeniculum vulgare, Justicia adhatoda and Urtica dioica as natural curatives by Batool R1, Salahuddin H1, Mahmood T1, Ismail M2.(PubMed)
The results of fennel efficacy were reported by several respectable institutes including the National Cancer Institute and the National Institute of Health.
Fennel (Foeniculum vulgare) is a plant species of the genus, belongings to Apiaceae (Umbelliferae), native to the Mediterranean, used in traditional and herbal medicine as warming, carminative, antispasmodic, antidepressant agent and to stimulate the appetite, ease indigestion, soothe coughing, reduce intestinal spasms, to regulate the menstrual cycle and relieve PMS,...
Nutrients
1. Carbohydrates
2. Fiber
3. Protein
4. Thiamine (Vitamin B1)
5. Riboflavin (Vitamin B2)
6. Niacin (Vitamin B3)
7. Pantothenic acid (B5)
8. Vitamin B6
9. Folate (Vitamin B9)
10. Vitamin C
11. Calcium
12. Copper
13. Iron
14. Magnesium
15. Molybdenum
16. Phosphorus
17. Potassium
18. Zinc
In the study to evaluate the efficacy of fennel seed methanolic extract (FSME) for its antioxidant, cytotoxic, and antitumor activities and for its capacity to serve as a nontoxic radioprotector in Swiss albino mice through injection of FSME, 100 mg/kg intraperitoneally into mice bearing EAC before exposed to three 2-Gy doses of gamma irradiation, researchers found at after 30 days, the application exerted a strong effect at the C50 (mean standard deviation 50% inhibitory concentrations) at a dose of 50 μg/mL for the MCF7 breast cancer cell line and 48 μg/mL for the Hepg-2 liver cancer cell line.
The treatment group also displayed a decreased level of MDA and improved natural antioxidants produced by the tissues of the host compared to the elevation of MDA and significantly reduced levels of catalase and GSH contents.
These results suggested that fennel seed methanolic extract (FSME) inhibited the overproduction of ROS caused by ingestion of doses of gamma irradiation through its anioxidants and enhanced antioxidants production of the mice tissue via the ratio of ROS and Antioxidants.
In other words, application of the fennel extract may have a potential in
* Reduced oxidative stress and protected mouse cells from damage caused by reactive oxygen species.
* Improved natural antioxidants and the oxidative stability of fatty foods during storage.
* Exhibited an antitumor effect by modulating lipid peroxidation and augmenting the antioxidant defense system in EAC-bearing mice with or without exposure to radiation.
Further illustration of the effect of herbal medicine in treatment of cancers and examine the cytoprotective effects, researchers at the National Institute of Health conducted a comparison of five herbal supplements, designated FB, FM, PP, HF, and FBL101, which contain different combinations of various natural herbs such as licorice, black cohosh, Dong Quai, false unicorn and vitex berry root against mice bearing CWR22R and PC3 prostate cancer xenografts.
According to the results of experiment,
* All herbal medicine, FB, FM, PP, HF, and FBL101 inhibited PC3 tumor growth by 53%, 75%, 80%, 81%, and 87%, respectively.
* In CWR22R tumors, applications of supplements exerted a similar effect in suppressing the cancer cells.
* All applications did not show inhibitory activity against levels of testosterone in compared to untreated mice. However, supplements PP and FBL101 exerted significantly reduced VEGF levels, a potent angiogenic factor with function in stimulated production of new blood vessels to ensure cell proliferation, in PC3 and CWR22R tumors.
* Intratumoral microvessel density was decreased in PC3 tumors treated with all five supplements but only in CWR22R tumors treated with HF.
Dr. Ng SS, the lead author said, "herbal supplements containing the aforementioned extracts inhibit the growth of prostate tumor xenografts, possibly in part by antiangiogenic mechanisms".
The above differentiation was supported by the Quaid-i-Azam University in the analysis of the antibacterial potential of some medicinal plants against multi-drug resistant (MDR) pathogens and anticancer effect against MCF-7 cell line.
According to the results of the report, the application of Ethanol extract of Foeniculum vulgare exhibited significant inhibition of cancer cells proliferation and induction of cancer cell apoptosis and reduction of growth of Klebsiella pneumonia, Serratia marcescens, and Methicillin-resistant S. aureus. Pseudomonas aeruginosa
Taken together, fennel and its extracts may be used as a functional food in the exertion of cytoprotection and antitumor activity.
For More information on yoga lessons tailor to a complete well being for women, please visit: YOGA FOR WOMEN
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Home page http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrients, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.
Sources
(1) Antioxidant and anticarcinogenic effects of methanolic extract and volatile oil of fennel seeds (Foeniculum vulgare) by Mohamad RH1, El-Bastawesy AM, Abdel-Monem MG, Noor AM, Al-Mehdar HA, Sharawy SM, El-Merzabani MM.(PubMed)
(2) Antitumor activity of herbal supplements in human prostate cancer xenografts implanted in immunodeficient mice by Ng SS1, Figg WD.(PubMed)
(3) Study of anticancer and antibacterial activities of Foeniculum vulgare, Justicia adhatoda and Urtica dioica as natural curatives by Batool R1, Salahuddin H1, Mahmood T1, Ismail M2.(PubMed)
Monday, August 16, 2021
Ginger, The Best to Normal Your Blood Cholesterol With No Side Effects
Ginger may be considered a functional food for the prevention and treatment of hyperlipidemia without inducing side effects, some scientists found.
Hyperlipidemia is a condition of abnormally high blood cholesterol.
In other words, people with hyperlipidemia have an elevated ratio of low-density lipoprotein/ high-density lipoprotein.
The normal and healthy ratio of healthy blood cholesterol is lower than 4/1.
The most common causes of high blood cholesterol are an unhealthy diet with high saturated and trans fat, red meat and processed foods, and few in fruits and vegetables.
In fact low intake of high-density lipoproteins which have the unique function to trnasport the excess cholesterol back to the liver.
In other words, the presence of high-density lipoproteins reduces the bad blood cholesterol in the bloodstream, thus decreasing the forming of plaque accumulated in the arterial wall, the major risk of heart disease.
Some researchers suggested that genetic preposition and certain medical conditions such as diabetes mellitus, kidney disease, and hypothyroidism may also increase the risk of hyperlipidemia.
The most common types of high-density lipoproteins can be found in olive oil which has been found to lower the inflammatory impact of LDL cholesterol on the body, beans, and legumes, whole grains. ... high-fiber fruit, and deep-sea fatty fish.
Therefore, by topical 2 spoonfuls of olive oil to your lunch salad every day, you may kiss the hyper cholesterol goodbye after six months.
Why it takes so long? because olive oil is a food and fat, not Western single-ingredient medicine.
Dr. Cullinen K in the nutrition team at the Rhode Island Department of Health, said, "Olive oil consumption increases HDL-cholesterol levels, while decreasing LDL-cholesterol levels, LDL susceptibility to oxidation and lipid peroxidation".
And, "The reduction of cellular oxidative stress, thrombogenicity and the formation of atheroma plague can explain the preventive effects of olive oil on atherosclerosis development".
These results clearly supported the use of oiler oil for the treatment in patients with hyperlipidemia.
Ginger (Zingiber officinale) or ginger root, the second superfood used for thousands of years by mankind, is the genus Zingiber, belonging to the family Zingiberaceae, native to Tamil.
The root has been used in traditional and Chinese medicine to treat dyspepsia, gastroparesis, constipation, edema, difficult urination, colic, etc.
With an aim to find a natural whole food for the treatment of abnormally high blood cholesterol with no side effects, researchers at the Tehran University of Medical Sciences assessed the effect of ginger consumption on glycemic status, lipid profile, and some inflammatory markers in patients with type 2 diabetes mellitus.
The double-blinded, placebo-controlled clinical trial included 70 type 2 diabetic patients allocated randomly into the ginger group and control group.
The treatment group consumed 1600 mg ginger versus 1600 mg wheat flour consumed by the placebo daily for 12 weeks.
At the end of the trial, researchers showed that the ginger treatment group exerts a significantly reduced fasting plasma glucose, HbA1C, insulin resistance, HOMA, triglyceride, total cholesterol, CRP, and PGE₂, compared to placebo group.
However, there were no significant differences in HDL, LD, and TNFα between two groups.
These results clearly suggested ginger has a strong effect in improving all parameters associated with diabetic symptoms.
Dr. Arablou T in the final report said, "Ginger improved insulin sensitivity and some fractions of lipid profile, and reduced CRP and PGE₂ in type 2 diabetic patients".
Other researchers in the concern of oxidative stress in the development and progression of diabetic nephropathy (DN)launched an investigation to examine the potential protective effect of ginger (Zingiber officinale) rhizome extract on hyperglycemia-induced oxidative stress, inflammation, and apoptosis.
Diabetes rats selected to the study were given 400 or 800 mg/kg/day Z. officinale extract for six weeks orally.
Treatment with Z. officinale not only improved all diabetic symptoms but also ameliorated hyperglycemia, hyperlipidemia and kidney function.
In addition, Z. officinale minimized the histological alterations in the kidney of diabetic rats
The evidence indicated Z. officinale extract significantly attenuated oxidative stress, inflammation and apoptosis, and enhanced antioxidant defenses in the diabetic kidney.
Taken all together, ginger may be considered a functional food for the prevention and treatment of abnormally high blood cholesterol with no side effects.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma ISSN 0975-6299.
Sources
(1) The effect of ginger consumption on glycemic status, lipid profile and some inflammatory markers in patients with type 2 diabetes mellitus by Arablou T1, Aryaeian N, Valizadeh M, Sharifi F, Hosseini A, Djalali M. (PubMed)
(2) POSSIBLE HYPOCHOLESTEROLEMIC EFFECT OF GINGER AND ROSEMARY OILS IN RATS. by Eissa FA1, Choudhry H1,2,3, Abdulaal WH1,3, Baothman OA1, Zeyadi M1, Moselhy SS1,4,5,6, Zamzami MA1,2. (PubMed)
(3) Ginger alleviates hyperglycemia-induced oxidative stress, inflammation, and apoptosis and protects rats against diabetic nephropathy by Al Hroob AM1, Abukhalil MH2, Alghonmeen RD3, Mahmoud AM4. (PubMed)
(4) Olive oil in the treatment of hypercholesterolemia by Cullinen K. (PubMed)
Hyperlipidemia is a condition of abnormally high blood cholesterol.
In other words, people with hyperlipidemia have an elevated ratio of low-density lipoprotein/ high-density lipoprotein.
The normal and healthy ratio of healthy blood cholesterol is lower than 4/1.
The most common causes of high blood cholesterol are an unhealthy diet with high saturated and trans fat, red meat and processed foods, and few in fruits and vegetables.
In fact low intake of high-density lipoproteins which have the unique function to trnasport the excess cholesterol back to the liver.
In other words, the presence of high-density lipoproteins reduces the bad blood cholesterol in the bloodstream, thus decreasing the forming of plaque accumulated in the arterial wall, the major risk of heart disease.
Some researchers suggested that genetic preposition and certain medical conditions such as diabetes mellitus, kidney disease, and hypothyroidism may also increase the risk of hyperlipidemia.
The most common types of high-density lipoproteins can be found in olive oil which has been found to lower the inflammatory impact of LDL cholesterol on the body, beans, and legumes, whole grains. ... high-fiber fruit, and deep-sea fatty fish.
Therefore, by topical 2 spoonfuls of olive oil to your lunch salad every day, you may kiss the hyper cholesterol goodbye after six months.
Why it takes so long? because olive oil is a food and fat, not Western single-ingredient medicine.
Dr. Cullinen K in the nutrition team at the Rhode Island Department of Health, said, "Olive oil consumption increases HDL-cholesterol levels, while decreasing LDL-cholesterol levels, LDL susceptibility to oxidation and lipid peroxidation".
And, "The reduction of cellular oxidative stress, thrombogenicity and the formation of atheroma plague can explain the preventive effects of olive oil on atherosclerosis development".
These results clearly supported the use of oiler oil for the treatment in patients with hyperlipidemia.
Ginger (Zingiber officinale) or ginger root, the second superfood used for thousands of years by mankind, is the genus Zingiber, belonging to the family Zingiberaceae, native to Tamil.
The root has been used in traditional and Chinese medicine to treat dyspepsia, gastroparesis, constipation, edema, difficult urination, colic, etc.
With an aim to find a natural whole food for the treatment of abnormally high blood cholesterol with no side effects, researchers at the Tehran University of Medical Sciences assessed the effect of ginger consumption on glycemic status, lipid profile, and some inflammatory markers in patients with type 2 diabetes mellitus.
The double-blinded, placebo-controlled clinical trial included 70 type 2 diabetic patients allocated randomly into the ginger group and control group.
The treatment group consumed 1600 mg ginger versus 1600 mg wheat flour consumed by the placebo daily for 12 weeks.
At the end of the trial, researchers showed that the ginger treatment group exerts a significantly reduced fasting plasma glucose, HbA1C, insulin resistance, HOMA, triglyceride, total cholesterol, CRP, and PGE₂, compared to placebo group.
However, there were no significant differences in HDL, LD, and TNFα between two groups.
These results clearly suggested ginger has a strong effect in improving all parameters associated with diabetic symptoms.
Dr. Arablou T in the final report said, "Ginger improved insulin sensitivity and some fractions of lipid profile, and reduced CRP and PGE₂ in type 2 diabetic patients".
Other researchers in the concern of oxidative stress in the development and progression of diabetic nephropathy (DN)launched an investigation to examine the potential protective effect of ginger (Zingiber officinale) rhizome extract on hyperglycemia-induced oxidative stress, inflammation, and apoptosis.
Diabetes rats selected to the study were given 400 or 800 mg/kg/day Z. officinale extract for six weeks orally.
Treatment with Z. officinale not only improved all diabetic symptoms but also ameliorated hyperglycemia, hyperlipidemia and kidney function.
In addition, Z. officinale minimized the histological alterations in the kidney of diabetic rats
The evidence indicated Z. officinale extract significantly attenuated oxidative stress, inflammation and apoptosis, and enhanced antioxidant defenses in the diabetic kidney.
Taken all together, ginger may be considered a functional food for the prevention and treatment of abnormally high blood cholesterol with no side effects.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma ISSN 0975-6299.
Sources
(1) The effect of ginger consumption on glycemic status, lipid profile and some inflammatory markers in patients with type 2 diabetes mellitus by Arablou T1, Aryaeian N, Valizadeh M, Sharifi F, Hosseini A, Djalali M. (PubMed)
(2) POSSIBLE HYPOCHOLESTEROLEMIC EFFECT OF GINGER AND ROSEMARY OILS IN RATS. by Eissa FA1, Choudhry H1,2,3, Abdulaal WH1,3, Baothman OA1, Zeyadi M1, Moselhy SS1,4,5,6, Zamzami MA1,2. (PubMed)
(3) Ginger alleviates hyperglycemia-induced oxidative stress, inflammation, and apoptosis and protects rats against diabetic nephropathy by Al Hroob AM1, Abukhalil MH2, Alghonmeen RD3, Mahmoud AM4. (PubMed)
(4) Olive oil in the treatment of hypercholesterolemia by Cullinen K. (PubMed)
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