Fennel Balances the Ratio of the Levels Free Radicals and Antioxidants in Our Body, Researchers Find

Imbalancing the ratio of the free radicals and antioxidants in the facilitation of oxidative stress was associated with the increased risk of the early onset of many chronic diseases, scientists found.

Fennel is a species of Foeniculum Vulgare, belonging to the family Apiaceae (Umbelliferae), and native to the shores of the Mediterranean, may process a potential effect in improving the levels of antioxidant enzymes produced by the human body, therefore, adding a portion of fennel on your daily diet should be helpful in reducing the risk of diabetics, rheumatoid arthritis, post-ischemic perfusion injury, myocardial infarction, cardiovascular diseases, chronic inflammation, stroke ...

Dr. Moylan JS, the lead author in the study "Oxidative stress, chronic disease, and muscle wasting", wrote, "If an overproduction of oxidants overwhelms the antioxidant defenses, oxidative damage of cells, tissues, and organs ensue. In some cases, oxidative stress is assigned a causal role in disease pathogenesis, whereas in others the link is less certain".

Free radicals are unstable molecules with unpaired electrons produced daily in our body, reactive oxygen species, and reactive nitrogen can induce a domino's effect by stealing an electron from other molecules, leading to a continued function that cannot stop until they are paired or inhibited by the presence of antioxidant molecules.

If the generation of free radicals exceeds the protective effects of antioxidants and some co-factors, the process can cause oxidative damage accumulated during the life cycle, leading to the disruption in the function of the cells.

There are many risk factors that can increase the overexpression of free radicals, including fried foods, alcohol, tobacco smoke, pesticides, and air pollutants.

Therefore by changing your diet pattern with more fruits and vegetables, whole grains, and less red meat and processed foods and maintaining an active lifestyle, you can absolutely balance the ratio of free radicals and antioxidants in your body, thus decreasing the risk of many related chronic diseases.

In the review of the traditional use of fennel essential oils (EO) possess antimicrobial, anti-inflammable oil and insect repellent, anti-cancer, and antioxidant properties, researchers launched a comparison of essential oil and their main constituents in Citrus aurantium, C. limon, Cupressus sempervirens, Eucalyptus globulus, Foeniculum vulgare, and Thymus vulgaris.


EO of fennel showed the best free radicals scavenging capacity compared to others.

Fennel EO also was most effective against lipid peroxidation along with EO of C. limon.

Interestingly, after in-depth analysis, researchers discovered the antioxidant and anti-inflammatory activities of the EOs were plant-species-dependent and not always attributable to the EOs main components.

Additionally, in the evaluation of chemical constituents from essential oil from (Foeniculum vulgare var. azoricum, Foeniculum vulgare var. dulce, and Foeniculum vulgare var. Vulgare, researchers suggested
* trans-Anethole, estragole, fenchone and limonene found highly abundant in all of the examined oils demonstrated strong antioxidant activities in the DPPH radical scavenging, lipid peroxidation, and metal chelating assays
* All 3 tested essentials display significant antimicrobial activities against two species of fungi, two species of Gram-negative, and two species of Gram-positive bacteria.


Finally, in the study to assess the efficacy of medicinal plants used traditionally in folk medicine as natural healing remedies with therapeutic effects such as prevention of cardiovascular diseases, inflammation disorders, or reducing the risk of cancer, researchers found that fennel in comparison to other medical exerts a strong antioxidant effect through many of its bioactive compound such as phenolic compounds.

However, Dr. Škrovánková S, the lead scientist in the concerns of some conditions that may affect the herbal quality, said, "The antioxidant properties of medicinal plants depend on the plant, its variety, environmental conditions, climatic and seasonal variations, geographical regions of growth, degree of ripeness, growing practices, and many other factors such as postharvest treatment and processing.


Taken all together, adding a portion of fennel into your diet may have a potential effect in increasing the levels of antioxidants in your body and countering the risk of overexpression of free radicals.

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Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
References
(1) Anti-oxidant, anti-inflammatory and anti-proliferative activities of Moroccan commercial essential oils by Aazza S, Lyoussi B, Megías C, Cortés-Giraldo I, Vioque J, Figueiredo AC, Miguel MG. (PubMed)
(4) Distillation time modifies essential oil yield, composition, and antioxidant capacity of fennel (Foeniculum vulgare Mill) by Zheljazkov VD1, Horgan T, Astatkie T, Schlegel V.(PubMed)
(3) Antioxidant activity and protecting health effects of common medicinal plants.
(4) Oxidative stress, chronic disease, and muscle wasting by Moylan JS1, Reid M. (PubMed)

Fennel Essential Oil and Extract, The Potent Anti Hypoglycemic Remedies, Scientists Reveal

Fennel may process a strong effect in preventing the abnormal rise of blood glucose in patients with diabetes, some scientists found.
In comparison to hyperglycemia with an excessive amount of glucose that circulates in the blood plasma, hypoglycemia is a condition of blood sugar, that falls below the levels of the normal range.

Patients with acute hypoglycemia may experience symptoms of clumsiness, trouble talking, confusion, loss of consciousness, seizures, or death.



Most cases of hyperglycemia in patients with diabetes are due to poor management. However, eating more carbohydrates than usual, less physical activity compared to a normal day being sick or high levels of stress in patients with diabetes also can cause blood glucose uptake.


Some researchers suggested that not getting the right dosage of insulin and glucose-lowering medication also causes increased blood glucose levels.


Long-term untreated hyperglycemia can elevate the onset of some serious complications including nerve damage, kidney damage and failure, heart disease, and eye disease, particularly in food and skin problems. or retinopathy foot problems caused by damaged nerves and poor blood flow skin problems, such as bacterial and fungal infections


Fennel (Foeniculum vulgare) is a plant species belongings to the family Apiaceae (Umbelliferae), native to the Mediterranean

The plant has been used in traditional and herbal medicine as a warming, carminative, antispasmodic, and antidepression agent and to stimulate the appetite, ease indigestion, soothe coughing, reduce intestinal spasms, regulate the menstrual cycle and relieve PMS,...

In the examine the antihyperglycemic activity of fennel essential oil in an animal model, researchers launched an investigation to evaluate rats induced by bacterial streptozotocin.

At the concentrations of 30 mg/kg body weight, the essential oil of fennel demonstrated a correction of hyperglycemia in the doses from 162.5 mg/dL to 81.97 ± 1.97 mg/dL by increasing the serum of antioxidants activity of serum glutathione peroxidase from 59.72 U/g Hb to 99.60 U/g Hb produced by the host.

The application also improved the pathological changes noticed in their kidney and pancreas, compared to the control group.

After making the final adjustment, researchers suggested that the study not only reaffirms the use of the essential oil of fennel for the treatment of hyperglycemia in folk medicine but also raises the possibility of essential oil inclusion in the antidiabetic drug industry.

Further analysis of the ethanolic and aqueous extracts of selected Sudanese plants, including fennel that is traditionally used to treat diabetes, researchers at the Khartoum College of Medical Sciences, suggested that fennel extract reveals a significant antioxidant activity in DPPH free radical scavenging assay.

However, the injection of fennel extract exhibited the highest toxicity.


These findings indicated that although fennel extract processes a substantial and positive effect in reducing the spike of blood glucose intake and the use of the fennel extract can only be prescribed by herbalists and professionals in the related field.

Additionally, in the testing, the hypoglycemic effect of a single dose of Gluconorm-5 (150, 300, and 600 mg/kg body weight) made up of five plants namely Camellia sinensis, Punica granatum, Macrotyloma uniflorum, Foeniculum vulgare and Trigonella foenum-graecum in normal, glucose loaded normal and diabetes-induced rats, researchers found that

* Fifteen days of oral feeding of the Gluconorm-5 (300 and 600 mg/kg) to diabetic rats resulted in a significant (P < 0.01) reduction of blood glucose, lipid profile, liver weight, and marker enzymes as compared to those rats in whom STZ induced toxicity was untreated.

* The diabetic rats treated with the formula showed expanded islets compared to the untreated diabetic rats, which showed shrunken islets.


* Treated rats received 300 mg/kg of Gluconorm-5 showed pronounced antidiabetic, antihyperlipidemic, and hepatoprotective effects.

This comprehensive differentiation showed that Gluconorm-5 processes potent antidiabetic antihyperlipidemic and hepatoprotective effect properties.

Taken altogether, fennel extract, and fennel essential oil used alone or combined with other herbal antidiabetic herbal medicine can be considered an adjuvant in the treatment of hyperglycemia and diabetes mellitus.


Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight

How To Get Rid Of Eye Floaters
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Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca


Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.


Sources
(1) Foeniculum vulgare Mill: A Review of Its Botany, Phytochemistry, Pharmacology, Contemporary Application, and Toxicology by Shamkant B. Badgujar,* Vainav V. Patel, and Atmaram H. Bandivdekar(PMC)
(2) A study of antioxidant activity, enzymatic inhibition and in vitro toxicity of selected traditional Sudanese plants with anti-diabetic potential by Hilmi Y1, Abushama MF, Abdalgadir H, Khalid A, Khalid H(PubMed)
(3) The Dietary Furocoumarin Imperatorin Increases Plasma GLP-1 Levels in Type 1-Like Diabetic Rats by Wang LY1,2,3, Cheng KC4, Li Y5,6, Niu CS7, Cheng JT8,9, Niu HS(PubMed)
(4) Antidiabetic antihyperlipidemic and hepato-protective effect of Gluconorm-5: A polyherbal formulation in steptozotocin induced hyperglycemic rats by Gengiah K1, Hari R2, Anbu J(PubMed)

#Herbal Ashwagandha Reduces the Risk of Memory Loss, Studies Find

Memory is one of the major functions of the brain that collects and stores data or information which is retrieved when needed.

In other words, memory is the retention of information over time that have a strong influence on future action.

Memory impairment is a condition of partial or complete loss of memory, depending on the quality of the neuron that has been affected.

Memory impairment other than the physical impact is a progressive disease that can lead to permanent loss of memory due to the gradual loss of neurons in the brain.

Memory impairment can be acute or chronic.

In acute impairment, memory is temporary loss in most cases associated with physical impact on the brain that causes injury of neurons.

Chronic memory impairment is the loss of memory that can get worse overtime found mostly in the elderly with neurodegenerative diseases, such as dementia.


In elderly or aging-induced memory loss is associated with the deterioration of a region of the brain involved in the formation and retrieval of memories, the hippocampus, and the reduced hormones and protein that protect and repair brain cells and stimulate neural growth.

The most common risk factors associated with memory loss in the general population are long-term use of certain medications, excessive alcohol drinking, smoking, drug abuse, depression, nutrient deficiency, stroke, and daily stress.

However, some researchers suggested the rise of memory impairment in the elderly probably is correlated to the promotion of the Western diet over the past few decades.

Dr. Scott E. Kanoski, the lead scientist in the review of the risk cognitive impairment in the Western diet consumption wrote, "Intake of saturated fats and simple carbohydrates, two of the primary components of a modern Western diet, is linked with the development of obesity and Alzheimer's Disease".


And, "Western diet intake is associated with cognitive impairment, with a specific emphasis on learning and memory functions that are dependent on the integrity of the hippocampus".

The results clearly stated if you are a Western diet follower, you are at a higher risk of memory impairment compared to healthy diet individuals.

Ashwagandha also is known as Withania somnifera is a nightshade plant in the genus of Withania, belonging to the family Solanaceae, native to the dry parts of India, North Africa, Middle East, and the Mediterranean. The herbal medicine has been considered as Indian ginseng and used in Ayurvedic medicine over 3000 years to treat tumors and tubercular glands, carbuncles, memory loss, and ulcers and considered as anti-stress, cognition-facilitating, anti-inflammatory, and anti-aging herbal medicine.

On finding a potent compound for the treatment of brain health, researchers examined the efficacy and safety of ashwagandha (Withania somnifera (L.) Dunal) on memory and cognitive functioning in adults with mild cognitive impairment (MCI).

The prospective, randomized, double-blind, placebo-controlled study included 50 adults assigned to the treatment of either ashwagandha-root extract (300 mg twice daily) or placebo for eight weeks.


According to the analysis of Wechsler Memory Scale III subtest scores for logical memory, at week 8, the ashwagandha treatment group exerted significant improvements in both immediate and general memory, compared with the placebo group.

Futhermore, verbal paired associates I (p = 0.042), faces I (p = 0.020), family pictures I (p = 0.006), logical memory II (p = 0.006) scores were also significantly increase compared to placebo.


According to the scores of Eriksen Flanker task (p = 0.002), Wisconsin Card Sort test (p = 0.014), Trail-Making test part A (p = 0.006), and the Mackworth Clock test (p = 0.009), ashwagandha treatment group also displayed a significantly greater improvement in executive function, sustained attention, and information-processing speed also compared to placebo.

Based on the findings, researchers said, "Ashwagandha may be effective in enhancing both immediate and general memory in people with MCI as well as improving executive function, attention, and information processing speed.".

Taken altogether, Ashwagandha may be considered a functional herb for the improvement of the brain health, pending the result of larger sample size and multicenter study



Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight

How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca


Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.

Sources
(1) Efficacy and Safety of Ashwagandha (Withania somnifera (L.) Dunal) Root Extract in Improving Memory and Cognitive Functions by Choudhary D1, Bhattacharyya S2, Bose S. (PubMed)
(2) Western Diet Consumption and Cognitive Impairment: Links to Hippocampal Dysfunction and Obesity by Scott E. Kanoski1 and Terry L. Davidson. (PMC)

Ginger, the Natural Antibiotics Alternative Functional Spice

Ginger may be considered a natural antibiotics alternative for the treatment of Candida albicans overgrowth without inducing any side effects, some scientists suggested.

Candida albicans is an opportunistic pathogenic yeast formed part of the commensal gastrointestinal mycobiota.

Candida albicans overgrowth is the most prevalent cause of fungal infections in humans.


Epidemiological studies strongly suggested that long-term users of antibiotics that cause an imbalance of the gut microbiome, weakened immune system, unhealthy diet, and women who are pregnant and hormone imbalance of hormone near menstruation are susceptible to the onset of the condition.


If you experience symptoms of oral thrush, recurring genital or urinary tract infections, persistent digestive issues, or joint pain. particularly, in the skin and nail fungal infections, you may have a yeast infection.

Please check with your doctor to rule out the Candida albicans overgrowth possibility.

Dr. Carol A. Kumamoto in the research team of infectious diseases in the study "Inflammation and gastrointestinal Candida colonization" suggested that Candida albicans overgrowth can be caused by other medical conditions, associated with a digestive disorder.

In the study, the doctor wrote, "Recent studies, however, show that high-level Candida colonization is associated with several diseases of the gastrointestinal tract. Further, results from animal models argue that Candida colonization delays the healing of inflammatory lesions and that inflammation promotes colonization".

And, "Both inflammatory bowel disease and gastrointestinal Candida colonization are associated with elevated levels of the pro-inflammatory cytokine IL-17. Therefore, effects on IL-17 levels may underlie the ability of Candida colonization to enhance inflammation".


These results strongly suggested, inflammation flames the overgrowth of Candida colonization in return, the overgrowth of Candida albicans induces persistently low-grade inflammation.

Ginger (Zingiber officinale) or ginger root, the second superfood used for thousands of years by mankind, is the genus Zingiber, belonging to the family Zingiberaceae, native to Tamil.

The root has been used in traditional and Chinese medicine to treat dyspepsia, gastroparesis, constipation, edema, difficult urination, colic, etc.


With an aim to find the natural ingredient or whole food for the replacement of conventional antibiotics without inducing any effects, researchers at the Teikyo University Institute of Medical Mycology investigated the effect of ginger against infection caused by Candida albicans.

4 preparations of the essential oils of young and mature rhizomes, air-dried and steamed rhizomes, and seed rhizomes of Zingiber officinale Roscoe (ginger) were compared in the study.

* All ginger essential oils processed a significant anti-Candida Albicans activity.

* Essential oil from the seed and air-dried rhizomes, exerted the highest effect compared to other preparations.

* The seed and air-dried rhizomes essential oils also had a potent inhibitory activity compared to ginger oleoresins obtained by ethanol and hypercritical carbon dioxide extraction and essential oils of 5 other plants in the family Zingiberaceae.
According to the chemical constituents assay, [6]-shogaol was most active against filament formation and growth of C. Albicans, followed by citral and [6]-gingerol.

Furthermore, ginger oleoresin, especially that obtained by ethanol extraction, with a high [6]-gingerol content exhibited potent anti-growth of C. Albicans compared to essential oils of ginger and other Zingiberaceae plants.



Moreover, a vitro joint study by the Institute of Science and Technology, researchers launched an investigation to evaluate the antimicrobial activity of 2% chlorhexidine gel (CHX) isolated from ginger as an auxiliary chemical substance and intracanal medications on Candida albicans.


The study included 48 single-rooted human teeth randomly divided into four groups (n = 12), according to intracanal medications used: (1) Calcium hydroxide + apyrogenic saline solution (Ca(OH)2 + SS), (2) 20% ginger glycolic extract (GEN), (3) calcium hydroxide + 20% ginger glycolic extract (Ca(OH)2 + GEN), (4) apyrogenic SS (control).


At the end of the experiment, researchers found that
* CHX was effective in the complete elimination of E. coli and C. Albicans.

* ChX also significantly reduced and then completely eliminated E. faecalis after intracanal medication.

* All other applications also revealed a reduction of endotoxins, the outer membrane of the cell wall of Gram-negative bacteria.

In the final report, the research team concluded, "CHX and intracanal medication used were able to eliminate the microorganisms from the root canal; the endotoxins were reduced, yet not completely eliminated".


These results strongly suggested that ginger bioactive compound processes a significant antibacterial activity, particularly in those of C. Albicans.


Taken all together, there is no doubt that ginger may be considered a functional food for the prevention and combined with primary medicine for the treatment of yeast infection with no side effects.

Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight

How To Get Rid Of Eye Floaters
Contrary To Professionals' Prediction, Floaters Can Be Cured Naturally

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca


Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.



Sources
(1) Anti-Candida and radical scavenging activities of essential oils and oleoresins of Zingiber officinale Roscoe and essential oils of other plants belonging to the family Zingiberaceae by Takahashi M1, Inouye S, Abe S.(PubMed)
(2) Action of Chlorhexidine, Zingiber officinale, and Calcium Hydroxide on Candidaalbicans, Enterococcus faecalis, Escherichia coli, and Endotoxin in the Root Canals by Valera MC1, Oliveira SA2, Maekawa LE2, Cardoso FG3, Chung A2, Silva SF2, Carvalho CA2. (PubMed)
(3) Inflammation and gastrointestinal Candida colonization by Carol A. Kumamoto. (PMC)

Herbal Bilberry, the Potential Treatment for Retinitis Pigmentosa, Researchers Say

Retinitis pigmentosa is a genetic condition characterized by the breakdown and gradual loss of cells in the retina.

The retina is the light-sensitive tissue lining the back of the eye. The function of the retina is to convert the light received into neural signals before sending them to the brain for visual recognition.
Most cases of retinitis pigmentosa are diagnosed during the teenage years and at birth. Some patients who carry the genetic preposition may develop the disease in later years.

The later diagnosed case is usually mild with slow progression compared to those presented in the teen years and at birth.

Most common symptoms of patients with retinitis pigmentosa are difficulty seeing at night and a loss of side (peripheral) vision. However, at the disease progress into the later stage, most patients also experience tunnel vision.

Conventionally, the treatment of retinitis pigmentosa is totally depending on the condition. The aim of treatment is to slow the vision loss and improve the patient quality of life.

Bilberry is a species of low-growing shrubs in the genus Vaccinium, belonging to the family Ericaceae, native to Northern Europe.

The plant berry has been used as herbs in traditional medicine for the treatment of acute and chronic diarrhea, gastritis, gastric ulcer, and duodenal ulcer, enterocolitis, ulcerative colitis, anemia, cystitis, kidney disease, and psoriasis, diabetes, etc.

Researchers on finding a natural compound for the treatment of retinitis pigmentosa with not side effects examined the effects of Bilberry (Vaccinium myrtillus L.) and lingonberry (Vacciniumvitis-idaea) containing high amounts of polyphenols (anthocyanins, resveratrol, and proanthocyanidins) against blue light a high-energy or short-wavelength visible light-induced retinal diseases such as age-related macular degeneration and retinitis pigmentosa.

According to the results from the cultured murine photoreceptor (661 W) cells exposed to blue LED light following treatment with B-ext, L-ext, or their constituents (cyanidin, delphinidin, malvidin, trans-resveratrol, and procyanidin B2), B-ext, L-ext, NAC, and their active components improved the viability of 661 W cells against the blue light damage.

The efficacy was found to be attributed to the injection of tested compounds in inhibiting the generation of intracellular ROS induced by the blue LED light irradiation.

Furthermore, B-ext and L-d with also protected the cells integrity against the activation of proteins by stimuli associated with the production of production of proinflammatory cytokines.

Moreover, B-ext, L-ext, and NAC inhibited proteins involved in cell death and autophagy against cells damaged by blue light.

Dr. Ogawa K the lead scientist said, "These findings suggest that B-ext and L-ext containing high amounts of polyphenols exert protective effects against blue LED light-induced retinal photoreceptor cell damage mainly through inhibition of ROS production and activation of pro-apoptotic proteins".

In a murine model of photo-stressed retina, researchers examined the bilberry extract through a stomach tube in Balb/c mice (750 mg/kg body weight) light-induced visual function impairment.

According to the tested assays, bilberry extract suppressed photo-induced apoptosis in the photoreceptor cell layer and shortening of the outer segments of rod and cone photoreceptors.


Bilberry extracts also reduced the levels of photo-induced reactive oxygen species (ROS), oxidative and endoplasmic reticulum (ER) stress markers observed by the analysis.

In other words, bilberry inhibited the ER stress in the retina, and at least in part, in Müller glial cells.

Based on the findings, researchers suggested, "bilberry extract attenuates photo-induced apoptosis and visual dysfunction most likely, and at least in part, through ROS reduction, and subsequent ER stress attenuation in the retina".

Taken altogether, bilberry processed abundantly bioactive compounds may be considered a function remedy for the prevention and treatment of age-related macular degeneration and retinitis pigmentosa, pending the validation of larger sample size and multicenter human study.


Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight

How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca


Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.

References
(1) Protective effects of bilberry and lingonberry extracts against blue light-emitting diode light-induced retinal photoreceptor cell damage in vitro by Ogawa K, Kuse Y, Tsuruma K, Kobayashi S, Shimazawa M, Hara H1. (PubMed)
(2) Neuroprotective effect of bilberry extract in a murine model of photo-stressed retina by Osada H1, Okamoto T1,2, Kawashima H1,2, Toda E1, Miyake S1,3, Nagai N1,2, Kobayashi S3, Tsubota K2, Ozawa Y. (PubMed)

Herbal Arctostaphylos uva-ursi, the Potential Anti Gastric/ Stomach Cancer Remedy

Scientists may have found a herbal remedy for the prevention and treatment of gastric cancer with no side effects, according to studies.

Gastric cancer or stomach cancer is a condition characterized by the abnormal growth of cells in the stomach tissue.

Most cases of gastric cancer start in the cells on the surface of the inner lining of the stomach tissue.

At stage 0, due to the gastric cancer cells being restricted or completely contained within the innermost layer of the lining, patients may not experience any symptoms.

However, at the later stage, the cancer cells can travel a distance away from the stomach to infect other tissue and organ, leading to secondary metastasis. If the tumor grows large enough, it may suppress the nearby blood vessels and nerve cells, causing blood to leak into the stomach and localized severe pain.

Besides common symptoms of cancers, patients with gastric cancer also experience some specific symptoms such as persistent abdominal (belly) pain., vague discomfort in the abdomen, a sense of fullness in the upper abdomen after eating a small meal, and heartburn or indigestion.

If you are having some of the above symptoms, please check with your doctor to rule out gastric cancer possibility.

Although there are many risk factors involved in the onset of the disease, such as family history, Helicobacter pylori infection, smoking, genetic preposition, certain stomach conditions, previous stomach surgery and type A blood, some researchers suggested that the most common cause of gastric cancer in the Western world is the Western diet-related disease.

Dr. Bertuccio P, the lead scientist at the Istituto di Ricerche Farmacologiche Mario Negri, in the concern of diet pattern in the risk of gastric cancer wrote, " An unfavorable role on GC emerged for the 'Western/unhealthy' dietary pattern, with an OR of 1.51 (95% CI: 1.21-1.89)" and "A favorable role on GC emerged for the 'Prudent/healthy', with an odds ratio (OR) of 0.75 [95% confidence interval (CI): 0.63-0.90], for the highest versus the lowest category".

The results strongly indicated the risk of gastric cancer is substantially higher in the Western diet group compared to the lower risk of a healthy diet.

Arctostaphylos uva-ursi is one of the species of Bearberry, in the genus Arctostaphylos, belonging to the family Ericaceae, native to northern North America, Asia, and Europe.

The herb plant has been used in traditional medicine as a diuretic agent and to treat urinary problems, including bladder infections, kidney infections, kidney stones, pelvic pain, etc.

The plant contains arbutin, ursolic acid, tannic acid, gallic acid, some essential oil and resin, hydroquinones tannins, phenolic glycosides, and flavonoids.

With an aim to find a natural ingredient or whole food for the treatment of gastric cancer, researchers at the Shanghai University of Traditional Chinese Medicine examined the effects of ursolic acid isolated from bearberry (Arctostaphylos uva-ursi) against the pathogenesis of gastric cancer characterized by excessive proliferation, abnormal differentiation, and reduced apoptosis.

Ursolic acid, extracted from the traditional Chinese medicine bearberry, inhibited gastric cancer cell proliferation and induced apoptosis.

Further assessment of anti-gastric cancer, researchers discovered that ursolic acid exhibited apoptotic activity through cancer cell degradation observed in the gastric cancer BGC-823 cells.


In other words, efficacy is associated with a translocation of cofilin-1 protein that activates the function of cytochrome c in programmed cell death from the mitochondria to the cytoplasm.

These results suggested that ursolic acid activated the function of proteins (the caspase cascade) associated with the cell death and apoptotic pathway.


Where Mitochondria are the major organelles involved in the biochemical execution of apoptosis


Dr. the lead scientist, after taking into account co and confounders said, "mitochondrial translocation of cofilin-1 might play a crucial role in the promotion of apoptosis and might be a key target for future treatment of human gastric cancer".


Taken altogether, Bearberry (herbal Arctostaphylos uva-ursi) processed a major compound of ursolic acid may be considered a functional remedy for the prevention and combined with other primary medicine for the treatment of gastric cancer, pending the confirmation of large sample size and multicenter human study.


However, intake of ursolic acid as a supplement should be taken with extreme care to prevent overdoses and acute liver toxicity.




Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight

How To Get Rid Of Eye Floaters
Contrary To Professional Prediction, Floaters Can Be Cured Naturally

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca


Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
References
(1) Mitochondrial translocation of cofilin-1 promotes apoptosis of gastric cancer BGC-823 cells induced by ursolic acid by Tang Q, Ji Q, Tang Y, Chen T, Pan G, Hu S, Bao Y, Peng W, Yin P.(PubMed)
(2) Dietary patterns and gastric cancer risk: a systematic review and meta-analysis by Bertuccio P1, Rosato V, Andreano A, Ferraroni M, Decarli A, Edefonti V, La Vecchia C. (PubMed)

Herbal Ashwagandha Processes Lowering Cholesterol Property

Cholesterol produced by the liver plays an essential role in a moderate amount in orchestrating the production of steroid hormone and vitamin D, building strong cell walls, and aiding the digestive system in absorbing nutrients and fluids.

Hyperlipidemia or high blood cholesterol is a medical condition characterized by abnormally high levels of lipids in the blood.

Blood cholesterol can be classified into
* The high-density lipoprotein also known as good cholesterol processes a function to return cholesterol to the liver.

* The low-density lipoprotein is also known as "bad" cholesterol processed a function aforementioned health benefits in a moderate amount.

In a healthy individual, unused cholesterol is returned to the liver. However, overexpression of "bad" cholesterol due to the consumption of a high-fat diet and reduced levels of "good" cholesterol can cause bad cholesterol to remain in the bloodstream, leading to hyperlipidemia.

The healthy ratio of total blood cholesterol ("bad"/ "good") is any number that is less than 4.

Patients with hyperlipidemia are asymptomatic. However, over time hyperlipidemia can cause plaque to accumulate on the arterial wall, leading to atherosclerosis, a major cause of heart disease and stroke.

According to the statistics provided by the CDC, in 2015–2016, more than 12% of adults age 20 and older had total cholesterol higher than 240 mg/dL, and more than 18% had high-density lipoprotein (HDL, or “good”) cholesterol levels less than 40 mg/dL in the US.

Some researchers suggested that the hyperlipidemic prevalence in the Western world may correlate to the promotion of a high-fat diet over the past few decades.

Dr. Karam I, the lead scientist in examing the said, "Hyperlipidemia, a group of metabolic disorders characterized by the elevated levels of lipids, is a major modifiable risk factor for atherosclerosis and cardiovascular disease [5]. These lipids include cholesterol, cholesterol esters, phospholipids, and triglycerides. Increased levels of LDL are related to the development of atherosclerosis [15,16].


And, "The result showed that there was a significant increase in hyperlipidemia biomarker which includes TC, TG, LDL, and HDL. There were histological changes in organs which confirm the previous result of blood lipid. That means high-fat diet successfully induces hyperlipidemia in rats, to make disease model of hyperlipidemia.".

The life-long condition of hyperlipidemia is treatable. By a change of diet and daily moderate exercise, you may control the condition without medication.

Ashwagandha also known as Withania somnifera is a nightshade plant in the genus of Withania, belonging to the family Solanaceae, native to the dry parts of India, North Africa, the Middle East, and the Mediterranean.

The herbal medicine has been considered Indian ginseng and used in Ayurvedic medicine for over 3000 years to treat tumors and tubercular glands, carbuncles, memory loss, and ulcers and considered an anti-stress, cognition-facilitating, anti-inflammatory, and anti-aging herbal medicine.

On finding a potent compound for the treatment of heart disease, researchers examined the effects of Ashwagandha on lowering blood cholesterol.

The study included rats induced by a high-fat diet treated by aqueous extract of fruits of Withania coagulans for 7 weeks.

According to the tested analysis during the experiment, administration of the extract showed a significantly reduced elevated serum cholesterol, triglycerides and lipoprotein levels.


In triton-induced hypercholesterolemia., the aqueous extract of fruits of Withania coagulans exerted a significantly hypolipidemic activity.

Furthermore, according to the tested analysis of the liver tissues of treated hyperlipidemic rats, the extracts also inhibited the degenerative changes, compared to hyperlipidemic controls.

Based on the findings, researchers said, "The hypolipidemic effect of W. coagulans fruits was found to be comparable to that of an Ayurvedic product containing Commiphora mukkul".

Taken altogether, Ashwagandha may be considered a functional herb for lowering blood cholesterol, pending the result of larger sample size and multicenter study

Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight

How To Get Rid Of Eye Floaters
Contrary To Professional's Prediction, Floaters Can Be Cured Naturally

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca


Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.

Sources
(1) Hypolipidemic and antioxidant activity of aqueous extract of fruit of Withaniacoagulans (Stocks) Dunal in cholesterol-fed hyperlipidemic rabbit model by Shukla K, Dikshit P, Shukla R, Sharma S, Gambhir JK. (PubMed)
(2) Hypolipidemic activity of aqueous extract of Withania coagulans Dunal in albino rats by Hemalatha S1, Wahi AK, Singh PN, Chansouria JP. (PubMed)
(2) Induce Hyperlipidemia in Rats Using High Fat Diet Investigating Blood Lipid and Histopathology by Karam I, Ma N, Yang Y-J, and Li J-Y. (The Journal of Hematology and Blood Disorders)