Saturday, August 12, 2023
Tocopherols Reduce the Risk and Progression of Prostate Cancer in Vivo
The prostate gland wrapped around around a tube (the urethra), is a gland of the male reproductive system found in front of the rectum and just below the bladder.
The prostate gland is a gland that makes and stores semen. It is located below the bladder and surrounds the tube that carries urine out of your body.
Additionally, the muscles of the prostate gland also play a critical role in propelling seminal fluid into the urethra during ejaculation
Symptoms of an enlarged prostate are associated with a natural impend the conversion of testosterone to DHT. Unfortunately, aging is not the only cause of enlarged prostate.
Prostate cancer is a medical and chronic condition caused by the growth of cells irregularly in the tissue of the prostate.
Most cases of prostate cancer start in the cells on the surface of the inner lining of the prostate gland.
According to the statistic provided by the Canadian Cancer Society, prostate cancer is the third most common cancer among Canadian men and the 3rd leading cause of death from cancer in men in Canada.
In 2017, approximately 21,300 men were diagnosed with prostate cancer, accounting for 21% of all new cancer cases in men.
Furthermore, approximately 1 in 7 Canadian men will develop prostate cancer during his lifetime and 1 in 29 will die from it.
The 5-year survival rate for most men with local or regional prostate cancer is nearly 100%.
In other words, For men diagnosed with prostate cancer that has not spread to other parts of the body, the 5-year survival rate is 100%.
However, the 5 years survival rate of prostate cancer that has spread to other parts of the body, is only 30%.
Tocopherols are phytochemicals of which many have vitamin E activity, belonging to the group of Lipids, found abundantly in butter, egg yolk, milk fat, some vegetable, and seed or nut oils, etc.
On finding a potential phytochemical for the treatment of chronic diseases, researchers examined the effect of tocopherols on prostate cancer.
The study included specific Pten-/- (Ptenp-/-) mice induced cancer by activation of AKT cancer promotion signaling, fed by Ptenp-/- mice with AIN93M or 0.2% δ-T supplemented diet, at the age of 6 or 12 weeks.According to the analysis,
* δ-T treatment reduced prostate adenocarcinoma multiplicity at the age of 40 weeks by 53.3 and 42.7%, respectively.
* Furthermore, the phosphorylation of AKT (T308) that promotes cancer growth and survival was reduced in the prostate of the mice administered the δ-T diet.
* δ-T diet also, reduced proliferation and increased apoptosis in the prostate cancer cell line without affecting the oxidative stress.
Interestingly, α-tocopherol (α-T) at 0.2% in the diet exhibited anti-prostate cancer cell activity with no effects on prostate adenocarcinoma multiplicity in the Ptenp-/- mice.
After taking other factors into account, researchers said, " δ-T inhibits the development of prostate adenocarcinoma in Ptenp-/- mice, mainly through inhibition of AKT activation".
Taken together, tocopherols may be considered an adjunct therapy in the treatment of prostate cancer, pending the confirmation of the larger sample size and multicenter human study.
Intake of tocopherols in the form of supplements should be taken with extreme care to prevent overdose acute liver toxicity.Norton's
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professional Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You. How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the Karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as the prostate-specificinternational journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Carotenoids, retinol, tocopherols, and prostate cancer risk: a pooled analysis of 15 studies by Key TJ1, Appleby PN2, Travis RC2, Albanes D3, Alberg AJ4, Barricarte A5, Black A3, Boeing H6, Bueno-de-Mesquita HB7, Chan JM8, Chen C9, Cook MB3, Donovan JL10, Galan P11, Gilbert R10, Giles GG12, Giovannucci E13, Goodman GE14, Goodman PJ15, Gunter MJ16, Hamdy FC17, Heliövaara M18, Helzlsouer KJ19, Henderson BE20, Hercberg S11, Hoffman-Bolton J21, Hoover RN3, Johansson M22, Khaw KT23, King IB24, Knekt P18, Kolonel LN25, Le Marchand L25, Männistö S18, Martin RM26, Meyer HE27, Mondul AM3, Moy KA3, Neal DE28, Neuhouser ML29, Palli D30, Platz EA31, Pouchieu C12, Rissanen H18, Schenk JM32, Severi G12, Stampfer MJ13, Tjønneland A33, Touvier M11, Trichopoulou A34, Weinstein SJ3, Ziegler RG3, Zhou CK3, Allen NE35; Endogenous Hormones Nutritional Biomarkers Prostate Cancer Collaborative Group. (PubMed)
(2) δ-Tocopherol inhibits the development of prostate adenocarcinoma in prostate specific Pten-/- mice by Wang H1, Yang X1, Liu A1, Wang G2, Bosland MC3, Yang CS. (PubMed)
Tuesday, May 16, 2023
#Pintobeans Lower Non-HDL Cholesterol Levels in Vivo, Researchers Find
Cholesterol is a waxy substance carried around by lipoproteins, that do not mix with water-based blood in our body.
Cholesterol is needed for our body to build cell walls and make hormones and vitamin D, and create bile salts that help to digest fat, particularly in the building of strong cell membranes. However, too much of it can be dangerous because cholesterol cannot dissolve in your blood.
There are 2 types of cholesterol. The low-density lipoprotein is also known as bad cholesterol which performs the aforementioned activity in the right levels and the high-density lipoprotein which returns cholesterol back to the liver for reuse.
However, overexpression of cholesterol can cause plaque building up on the arterial wall, leading to arterial narrowing, wall stiffness, and hardening, some major causes of heart disease and stroke.
Although high blood cholesterol does not induce any symptoms, a prolonged period of uncontrolled high blood cholesterol can cause complications of chest pain, the early sign of coronary artery disease, heart attack,.... and stroke.
According to medical guidelines, the normal goal of non-HDL cholesterol levels should be 30 mg/dL higher than the LDL cholesterol level.
For example, if your non-HDL cholesterol level= is LDL cholesterol.+ 30 mg/dL = 130 mg/dL and your HDL is 40 mg/dL = Non-HDL-c/HDL-c ratio of 3.25, the ideal range of the ratio.
The healthy ratio of blood cholesterol is 4 (LDL)/1 (HDL). If you have a number that is lowers than 4, you have healthy blood cholesterol.
Hyperlipidemia is one member of the cluster conditions of metabolic syndrome, therefore, if you have a number that is higher than 4, your risk of cardiovascular is increased compared to people with healthy levels.
On finding a natural ingredient for the prevention and treatment of diseases associated with high blood cholesterol, scientists examined the changes in cholesterol metabolism in response to whole pinto beans (wPB) and their hulls (hPB) supplemented into a diet rich in saturated fat in hamsters.
The pinto bean is also known as the common bean, genus Phaseolus and the family Fabaceae. It has a mottled appearance of darker reddish-brown spots on a lighter brownish-beige background, thus appearing painted or spotted.
The study included forty-four 9-wk-old male Golden Syrian hamsters that were randomly assigned to 4 diet groups (n = 11), including a 5% (wt:wt) fat diet [normal-fat diet (NF)], a 15% (wt:wt) fat diet [diet rich in saturated fat (HSF), saturated fatty acids accounted for 70% of total fatty acids], or HSF supplemented with 5% (wt:wt) wPB or 0.5% (wt:wt) hPB for 4 wk.
According to the plasma, liver, intestinal, and fecal samples that were collected to evaluate multiple cholesterol markers and gene targets,
* The plasma non-high-density lipoprotein (non-HDL) concentration was significantly reduced in the wPB- and hPB-supplemented groups by 31.9 ± 3.5% and 53.6 ± 3.2%, respectively, compared to the HSF group (P < 0.01), to concentrations comparable with the NF group
* The wPB-supplemented hamsters had significantly lower liver cholesterol (45.1%, P < 0.001) and higher fecal cholesterol concentrations (94.8%, P = 0.001) than those of the HSF group.
* The expressions of hepatic 3-hydroxy-3-methylglutaryl CoA reductase (Hmgcr) and small intestinal acyl-coenzyme A: cholesterol acyltransferase 2 (Acat2) associated with the elevation of blood cholesterol were significantly decreased in animals administered wPB (by 89.1% and 63.8%, respectively) and hPB (by 72.9% and 47.7%, respectively) compared to the HSF-fed counterparts (P < 0.05).
Based on the results, researchers suggest, "Pinto beans remediated high cholesterol induced by HSF in male hamsters by decreasing hepatic cholesterol synthesis and intestinal cholesterol absorption, effects which were partially exerted by the hulls".
Taken altogether, Pinto beans may be considered s functional for the treatment of high blood cholesterol, pending the confirmation of the larger sample size and multicenter human study.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You. How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the Karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Pinto Beans (Phaseolus vulgaris L.) Lower Non-HDL Cholesterol in Hamsters Fed a Diet Rich in Saturated Fat and Act on Genes Involved in Cholesterol Homeostasis by Nguyen AT1,2, Althwab S3,4, Qiu H3, Zbasnik R1, Urrea C5, Carr TP3, Schlegel V. (PubMed)
Cholesterol is needed for our body to build cell walls and make hormones and vitamin D, and create bile salts that help to digest fat, particularly in the building of strong cell membranes. However, too much of it can be dangerous because cholesterol cannot dissolve in your blood.
There are 2 types of cholesterol. The low-density lipoprotein is also known as bad cholesterol which performs the aforementioned activity in the right levels and the high-density lipoprotein which returns cholesterol back to the liver for reuse.
However, overexpression of cholesterol can cause plaque building up on the arterial wall, leading to arterial narrowing, wall stiffness, and hardening, some major causes of heart disease and stroke.
Although high blood cholesterol does not induce any symptoms, a prolonged period of uncontrolled high blood cholesterol can cause complications of chest pain, the early sign of coronary artery disease, heart attack,.... and stroke.
According to medical guidelines, the normal goal of non-HDL cholesterol levels should be 30 mg/dL higher than the LDL cholesterol level.
For example, if your non-HDL cholesterol level= is LDL cholesterol.+ 30 mg/dL = 130 mg/dL and your HDL is 40 mg/dL = Non-HDL-c/HDL-c ratio of 3.25, the ideal range of the ratio.
The healthy ratio of blood cholesterol is 4 (LDL)/1 (HDL). If you have a number that is lowers than 4, you have healthy blood cholesterol.
Hyperlipidemia is one member of the cluster conditions of metabolic syndrome, therefore, if you have a number that is higher than 4, your risk of cardiovascular is increased compared to people with healthy levels.
On finding a natural ingredient for the prevention and treatment of diseases associated with high blood cholesterol, scientists examined the changes in cholesterol metabolism in response to whole pinto beans (wPB) and their hulls (hPB) supplemented into a diet rich in saturated fat in hamsters.
The pinto bean is also known as the common bean, genus Phaseolus and the family Fabaceae. It has a mottled appearance of darker reddish-brown spots on a lighter brownish-beige background, thus appearing painted or spotted.
The study included forty-four 9-wk-old male Golden Syrian hamsters that were randomly assigned to 4 diet groups (n = 11), including a 5% (wt:wt) fat diet [normal-fat diet (NF)], a 15% (wt:wt) fat diet [diet rich in saturated fat (HSF), saturated fatty acids accounted for 70% of total fatty acids], or HSF supplemented with 5% (wt:wt) wPB or 0.5% (wt:wt) hPB for 4 wk.
According to the plasma, liver, intestinal, and fecal samples that were collected to evaluate multiple cholesterol markers and gene targets,
* The plasma non-high-density lipoprotein (non-HDL) concentration was significantly reduced in the wPB- and hPB-supplemented groups by 31.9 ± 3.5% and 53.6 ± 3.2%, respectively, compared to the HSF group (P < 0.01), to concentrations comparable with the NF group
* The wPB-supplemented hamsters had significantly lower liver cholesterol (45.1%, P < 0.001) and higher fecal cholesterol concentrations (94.8%, P = 0.001) than those of the HSF group.
* The expressions of hepatic 3-hydroxy-3-methylglutaryl CoA reductase (Hmgcr) and small intestinal acyl-coenzyme A: cholesterol acyltransferase 2 (Acat2) associated with the elevation of blood cholesterol were significantly decreased in animals administered wPB (by 89.1% and 63.8%, respectively) and hPB (by 72.9% and 47.7%, respectively) compared to the HSF-fed counterparts (P < 0.05).
Based on the results, researchers suggest, "Pinto beans remediated high cholesterol induced by HSF in male hamsters by decreasing hepatic cholesterol synthesis and intestinal cholesterol absorption, effects which were partially exerted by the hulls".
Taken altogether, Pinto beans may be considered s functional for the treatment of high blood cholesterol, pending the confirmation of the larger sample size and multicenter human study.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You. How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the Karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Pinto Beans (Phaseolus vulgaris L.) Lower Non-HDL Cholesterol in Hamsters Fed a Diet Rich in Saturated Fat and Act on Genes Involved in Cholesterol Homeostasis by Nguyen AT1,2, Althwab S3,4, Qiu H3, Zbasnik R1, Urrea C5, Carr TP3, Schlegel V. (PubMed)
Friday, April 7, 2023
#Ginger and #ShellGinger in the Promotion of Healthy Longevity, According to Studies
Scientists may have a pungent spice that processes a potential for the promotion of healthy longevity, according to the study.
Compared to life expectancy which is the average number of years remaining of a given age or living of a certain group's people, longevity is a long life out of the boundary of the life expectancy.
Truly, we all dream to live healthy and with longevity. However how many of us can maintain health and prevent the onset of chronic disease?
Some researchers suggested that by following a healthy lifestyle and moderate exercise healthy longevity can be achieved.
Dr. Mehta N in the study of the healthy lifestyle impact on life expectancy wrote, "Compared to the whole US population, those with such a favorable behavioral profile had a life expectancy at age fifty that was seven years longer, and they experienced a delay in the onset of disability of up to six years".
The results clearly suggested the massively damaging effects caused by unhealthy behavioral risks on health at older ages.
Furthermore, Dr. Vincent Gremeaux and colleagues on the differentiation of exercise and longevity said, "As the number of older individuals continues to increase, it is important to develop interventions that can be easily implemented and contribute to “successful aging”".
And, " In addition to a healthy diet and psychosocial well-being, the benefits of regular exercise on mortality, and the prevention and control of chronic disease affecting both life expectancy and quality of life are well established".
Regularly moderate exercise has been found to have partially reverse effects on the aging process on physiological functions and preserve functional capability in the elderly.
Epidemiological studies strongly suggested that healthy longevity can be achieved by maintaining a minimum quantity and quality of exercise, preventing the development of certain cancers, and lowering the risk of osteoporosis.
Ginger (Zingiber officinale) or ginger root, the second superfood used for thousands of years by mankind, is the genus Zingiber, belonging to the family Zingiberaceae, native to Tamil.
The root has been used in traditional and Chinese medicine to treat dyspepsia, gastroparesis, constipation, edema, difficult urination, colic, etc.
Researchers on finding a bioactive compound for healthy longevity examined the shell ginger (Alpinia zerumbet (Pers.) B.L. Burtt & R.M. Sm) of the ginger family (Zingiberaceae) activity in the population in the Okinawa Islands of Japan.
According to the review of the literature, culinary shell ginger may contribute to longevity among the population in Okinawa probably due to the procession of phytochemical content with antioxidants and its effects on anti-obesity properties.
Some researchers suggested that the longevity of the population may also be attributed to the shell ginger in the promotion of health in reduced diseases by exhibiting anti-inflammatory, fungistatic, and antibacterial activities against Escherichia coli, Bacillus subtilis, and Bacillus cereus activity.
Shell ginger also is proven to have a positive effect on neuraminidase enzymes and inhibition of human immunodeficiency virus (HIV-1).
Dr. Rolf Teschke in the examination of the mortality rate of Japan's general public compared to the population on the island wrote, "Cardiovascular disease as the top cause of death for both sexes and neoplasms as the second leading cause of death in Japan nationally, with major variations among the prefectures"
And, " Comparing Japan overall with Okinawa, the mean mortality rates from ischaemic heart disease, Alzheimer’s disease, breast cancer, and oesophageal cancer were not remarkably different. However, for Okinawa, four death categories were significantly lower, including ischaemic stroke, stomach cancer, pancreatic cancer, and liver cancer due to hepatitis C.
The finding clearly suggested that the intake of shell ginger which was not found in other areas in Japan may contribute to the healthy longevity of the population in the Okinawa Islands of Japan.
In a joint study led by Woosuk University, Korean scientists evaluated the compound 6-gingerol longevity-promoting activity. isolated from the most active ethyl acetate soluble fraction on Caenorhabditis elegans (C. elegans).
Injection of 6 gingerol elevated the survival rate of worms against stressful environments including thermal, osmotic, and oxidative conditions.
The bioactive compound elevated the antioxidant enzyme activities of C. elegans and showed a dose-depend reduction of intracellular reactive oxygen species (ROS) accumulation in worms.
Furthermore, 6 gingerols also demonstrated increased stress tolerance, leading to the promotion of stress resistance proteins.
The findings strongly suggest that 6-gingerol exerted longevity-promoting activities independently of these factors and could extend the human lifespan.
Taken altogether, ginger and shell ginger may be considered functional foods for the promotion of healthy longevity with no side effects, pending the confirmation of a large sample size and multicenter human study.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals' Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma ISSN 0975-6299.
Sources
(1) Longevity and Stress Resistant Property of 6-Gingerol from Zingiber officinale Roscoe in Caenorhabditis elegans by Eun Byeol Lee,1 Jun Hyeong Kim,1 Chang Wan An,1 Yeong Jee Kim,1 Yun Jeong Noh,1Su Jin Kim,1 Ju-Eun Kim,1 Abinash Chandra Shrestha,1 Ha-Neul Ham,1 Jae-Yoon Leem,1Hyung-Kwon Jo,2 Dae-Sung Kim,2 Kwang Hyun Moon,3 Jeong Ho Lee,3 Kyung Ok Jeong,3 andDae Keun Kim. (PubMed)
(2) Viewpoint: A Contributory Role of Shell Ginger (Alpinia zerumbet) for Human Longevity in Okinawa, Japan? by Rolf Teschke1,* and Tran Dang Xuan. (PMC)
(3) The Population Health Benefits Of A Healthy Lifestyle: Life Expectancy Increased And Onset Of Disability Delayed by Mehta N1, Myrskylä M. (PubMed)
(4) Exercise and longevity by Vincent Gremeaux, Duxabcdef, MathieuGay, RomualdLeperse, Philippe Sosneraghi, MartinJuneau, AnilNigam. (Science Direct)
Truly, we all dream to live healthy and with longevity. However how many of us can maintain health and prevent the onset of chronic disease?
Some researchers suggested that by following a healthy lifestyle and moderate exercise healthy longevity can be achieved.
Dr. Mehta N in the study of the healthy lifestyle impact on life expectancy wrote, "Compared to the whole US population, those with such a favorable behavioral profile had a life expectancy at age fifty that was seven years longer, and they experienced a delay in the onset of disability of up to six years".
The results clearly suggested the massively damaging effects caused by unhealthy behavioral risks on health at older ages.
Furthermore, Dr. Vincent Gremeaux and colleagues on the differentiation of exercise and longevity said, "As the number of older individuals continues to increase, it is important to develop interventions that can be easily implemented and contribute to “successful aging”".
And, " In addition to a healthy diet and psychosocial well-being, the benefits of regular exercise on mortality, and the prevention and control of chronic disease affecting both life expectancy and quality of life are well established".
Regularly moderate exercise has been found to have partially reverse effects on the aging process on physiological functions and preserve functional capability in the elderly.
Epidemiological studies strongly suggested that healthy longevity can be achieved by maintaining a minimum quantity and quality of exercise, preventing the development of certain cancers, and lowering the risk of osteoporosis.
Ginger (Zingiber officinale) or ginger root, the second superfood used for thousands of years by mankind, is the genus Zingiber, belonging to the family Zingiberaceae, native to Tamil.
The root has been used in traditional and Chinese medicine to treat dyspepsia, gastroparesis, constipation, edema, difficult urination, colic, etc.
Researchers on finding a bioactive compound for healthy longevity examined the shell ginger (Alpinia zerumbet (Pers.) B.L. Burtt & R.M. Sm) of the ginger family (Zingiberaceae) activity in the population in the Okinawa Islands of Japan.
According to the review of the literature, culinary shell ginger may contribute to longevity among the population in Okinawa probably due to the procession of phytochemical content with antioxidants and its effects on anti-obesity properties.
Some researchers suggested that the longevity of the population may also be attributed to the shell ginger in the promotion of health in reduced diseases by exhibiting anti-inflammatory, fungistatic, and antibacterial activities against Escherichia coli, Bacillus subtilis, and Bacillus cereus activity.
Shell ginger also is proven to have a positive effect on neuraminidase enzymes and inhibition of human immunodeficiency virus (HIV-1).
Dr. Rolf Teschke in the examination of the mortality rate of Japan's general public compared to the population on the island wrote, "Cardiovascular disease as the top cause of death for both sexes and neoplasms as the second leading cause of death in Japan nationally, with major variations among the prefectures"
And, " Comparing Japan overall with Okinawa, the mean mortality rates from ischaemic heart disease, Alzheimer’s disease, breast cancer, and oesophageal cancer were not remarkably different. However, for Okinawa, four death categories were significantly lower, including ischaemic stroke, stomach cancer, pancreatic cancer, and liver cancer due to hepatitis C.
The finding clearly suggested that the intake of shell ginger which was not found in other areas in Japan may contribute to the healthy longevity of the population in the Okinawa Islands of Japan.
In a joint study led by Woosuk University, Korean scientists evaluated the compound 6-gingerol longevity-promoting activity. isolated from the most active ethyl acetate soluble fraction on Caenorhabditis elegans (C. elegans).
Injection of 6 gingerol elevated the survival rate of worms against stressful environments including thermal, osmotic, and oxidative conditions.
The bioactive compound elevated the antioxidant enzyme activities of C. elegans and showed a dose-depend reduction of intracellular reactive oxygen species (ROS) accumulation in worms.
Furthermore, 6 gingerols also demonstrated increased stress tolerance, leading to the promotion of stress resistance proteins.
The findings strongly suggest that 6-gingerol exerted longevity-promoting activities independently of these factors and could extend the human lifespan.
Taken altogether, ginger and shell ginger may be considered functional foods for the promotion of healthy longevity with no side effects, pending the confirmation of a large sample size and multicenter human study.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals' Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma ISSN 0975-6299.
Sources
(1) Longevity and Stress Resistant Property of 6-Gingerol from Zingiber officinale Roscoe in Caenorhabditis elegans by Eun Byeol Lee,1 Jun Hyeong Kim,1 Chang Wan An,1 Yeong Jee Kim,1 Yun Jeong Noh,1Su Jin Kim,1 Ju-Eun Kim,1 Abinash Chandra Shrestha,1 Ha-Neul Ham,1 Jae-Yoon Leem,1Hyung-Kwon Jo,2 Dae-Sung Kim,2 Kwang Hyun Moon,3 Jeong Ho Lee,3 Kyung Ok Jeong,3 andDae Keun Kim. (PubMed)
(2) Viewpoint: A Contributory Role of Shell Ginger (Alpinia zerumbet) for Human Longevity in Okinawa, Japan? by Rolf Teschke1,* and Tran Dang Xuan. (PMC)
(3) The Population Health Benefits Of A Healthy Lifestyle: Life Expectancy Increased And Onset Of Disability Delayed by Mehta N1, Myrskylä M. (PubMed)
(4) Exercise and longevity by Vincent Gremeaux, Duxabcdef, MathieuGay, RomualdLeperse, Philippe Sosneraghi, MartinJuneau, AnilNigam. (Science Direct)
Tuesday, January 10, 2023
Fennel Balances the Ratio of the Levels Free Radicals and Antioxidants in Our Body, Researchers Find
Imbalancing the ratio of the free radicals and antioxidants in the facilitation of oxidative stress was associated with the increased risk of the early onset of many chronic diseases, scientists found.
Fennel is a species of Foeniculum Vulgare, belonging to the family Apiaceae (Umbelliferae), and native to the shores of the Mediterranean, may process a potential effect in improving the levels of antioxidant enzymes produced by the human body, therefore, adding a portion of fennel on your daily diet should be helpful in reducing the risk of diabetics, rheumatoid arthritis, post-ischemic perfusion injury, myocardial infarction, cardiovascular diseases, chronic inflammation, stroke ...
Dr. Moylan JS, the lead author in the study "Oxidative stress, chronic disease, and muscle wasting", wrote, "If an overproduction of oxidants overwhelms the antioxidant defenses, oxidative damage of cells, tissues, and organs ensue. In some cases, oxidative stress is assigned a causal role in disease pathogenesis, whereas in others the link is less certain".
Free radicals are unstable molecules with unpaired electrons produced daily in our body, reactive oxygen species, and reactive nitrogen can induce a domino's effect by stealing an electron from other molecules, leading to a continued function that cannot stop until they are paired or inhibited by the presence of antioxidant molecules.
If the generation of free radicals exceeds the protective effects of antioxidants and some co-factors, the process can cause oxidative damage accumulated during the life cycle, leading to the disruption in the function of the cells.
There are many risk factors that can increase the overexpression of free radicals, including fried foods, alcohol, tobacco smoke, pesticides, and air pollutants.
Therefore by changing your diet pattern with more fruits and vegetables, whole grains, and less red meat and processed foods and maintaining an active lifestyle, you can absolutely balance the ratio of free radicals and antioxidants in your body, thus decreasing the risk of many related chronic diseases.
In the review of the traditional use of fennel essential oils (EO) possess antimicrobial, anti-inflammable oil and insect repellent, anti-cancer, and antioxidant properties, researchers launched a comparison of essential oil and their main constituents in Citrus aurantium, C. limon, Cupressus sempervirens, Eucalyptus globulus, Foeniculum vulgare, and Thymus vulgaris.
EO of fennel showed the best free radicals scavenging capacity compared to others.
Fennel EO also was most effective against lipid peroxidation along with EO of C. limon.
Interestingly, after in-depth analysis, researchers discovered the antioxidant and anti-inflammatory activities of the EOs were plant-species-dependent and not always attributable to the EOs main components.
Additionally, in the evaluation of chemical constituents from essential oil from (Foeniculum vulgare var. azoricum, Foeniculum vulgare var. dulce, and Foeniculum vulgare var. Vulgare, researchers suggested
* trans-Anethole, estragole, fenchone and limonene found highly abundant in all of the examined oils demonstrated strong antioxidant activities in the DPPH radical scavenging, lipid peroxidation, and metal chelating assays
* All 3 tested essentials display significant antimicrobial activities against two species of fungi, two species of Gram-negative, and two species of Gram-positive bacteria.
Finally, in the study to assess the efficacy of medicinal plants used traditionally in folk medicine as natural healing remedies with therapeutic effects such as prevention of cardiovascular diseases, inflammation disorders, or reducing the risk of cancer, researchers found that fennel in comparison to other medical exerts a strong antioxidant effect through many of its bioactive compound such as phenolic compounds.
However, Dr. Škrovánková S, the lead scientist in the concerns of some conditions that may affect the herbal quality, said, "The antioxidant properties of medicinal plants depend on the plant, its variety, environmental conditions, climatic and seasonal variations, geographical regions of growth, degree of ripeness, growing practices, and many other factors such as postharvest treatment and processing.
Taken all together, adding a portion of fennel into your diet may have a potential effect in increasing the levels of antioxidants in your body and countering the risk of overexpression of free radicals.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals' Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
References
(1) Anti-oxidant, anti-inflammatory and anti-proliferative activities of Moroccan commercial essential oils by Aazza S, Lyoussi B, Megías C, Cortés-Giraldo I, Vioque J, Figueiredo AC, Miguel MG. (PubMed)
(4) Distillation time modifies essential oil yield, composition, and antioxidant capacity of fennel (Foeniculum vulgare Mill) by Zheljazkov VD1, Horgan T, Astatkie T, Schlegel V.(PubMed)
(3) Antioxidant activity and protecting health effects of common medicinal plants.
(4) Oxidative stress, chronic disease, and muscle wasting by Moylan JS1, Reid M. (PubMed)
Fennel is a species of Foeniculum Vulgare, belonging to the family Apiaceae (Umbelliferae), and native to the shores of the Mediterranean, may process a potential effect in improving the levels of antioxidant enzymes produced by the human body, therefore, adding a portion of fennel on your daily diet should be helpful in reducing the risk of diabetics, rheumatoid arthritis, post-ischemic perfusion injury, myocardial infarction, cardiovascular diseases, chronic inflammation, stroke ...
Dr. Moylan JS, the lead author in the study "Oxidative stress, chronic disease, and muscle wasting", wrote, "If an overproduction of oxidants overwhelms the antioxidant defenses, oxidative damage of cells, tissues, and organs ensue. In some cases, oxidative stress is assigned a causal role in disease pathogenesis, whereas in others the link is less certain".
Free radicals are unstable molecules with unpaired electrons produced daily in our body, reactive oxygen species, and reactive nitrogen can induce a domino's effect by stealing an electron from other molecules, leading to a continued function that cannot stop until they are paired or inhibited by the presence of antioxidant molecules.
If the generation of free radicals exceeds the protective effects of antioxidants and some co-factors, the process can cause oxidative damage accumulated during the life cycle, leading to the disruption in the function of the cells.
There are many risk factors that can increase the overexpression of free radicals, including fried foods, alcohol, tobacco smoke, pesticides, and air pollutants.
Therefore by changing your diet pattern with more fruits and vegetables, whole grains, and less red meat and processed foods and maintaining an active lifestyle, you can absolutely balance the ratio of free radicals and antioxidants in your body, thus decreasing the risk of many related chronic diseases.
In the review of the traditional use of fennel essential oils (EO) possess antimicrobial, anti-inflammable oil and insect repellent, anti-cancer, and antioxidant properties, researchers launched a comparison of essential oil and their main constituents in Citrus aurantium, C. limon, Cupressus sempervirens, Eucalyptus globulus, Foeniculum vulgare, and Thymus vulgaris.
EO of fennel showed the best free radicals scavenging capacity compared to others.
Fennel EO also was most effective against lipid peroxidation along with EO of C. limon.
Interestingly, after in-depth analysis, researchers discovered the antioxidant and anti-inflammatory activities of the EOs were plant-species-dependent and not always attributable to the EOs main components.
Additionally, in the evaluation of chemical constituents from essential oil from (Foeniculum vulgare var. azoricum, Foeniculum vulgare var. dulce, and Foeniculum vulgare var. Vulgare, researchers suggested
* trans-Anethole, estragole, fenchone and limonene found highly abundant in all of the examined oils demonstrated strong antioxidant activities in the DPPH radical scavenging, lipid peroxidation, and metal chelating assays
* All 3 tested essentials display significant antimicrobial activities against two species of fungi, two species of Gram-negative, and two species of Gram-positive bacteria.
Finally, in the study to assess the efficacy of medicinal plants used traditionally in folk medicine as natural healing remedies with therapeutic effects such as prevention of cardiovascular diseases, inflammation disorders, or reducing the risk of cancer, researchers found that fennel in comparison to other medical exerts a strong antioxidant effect through many of its bioactive compound such as phenolic compounds.
However, Dr. Škrovánková S, the lead scientist in the concerns of some conditions that may affect the herbal quality, said, "The antioxidant properties of medicinal plants depend on the plant, its variety, environmental conditions, climatic and seasonal variations, geographical regions of growth, degree of ripeness, growing practices, and many other factors such as postharvest treatment and processing.
Taken all together, adding a portion of fennel into your diet may have a potential effect in increasing the levels of antioxidants in your body and countering the risk of overexpression of free radicals.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals' Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
References
(1) Anti-oxidant, anti-inflammatory and anti-proliferative activities of Moroccan commercial essential oils by Aazza S, Lyoussi B, Megías C, Cortés-Giraldo I, Vioque J, Figueiredo AC, Miguel MG. (PubMed)
(4) Distillation time modifies essential oil yield, composition, and antioxidant capacity of fennel (Foeniculum vulgare Mill) by Zheljazkov VD1, Horgan T, Astatkie T, Schlegel V.(PubMed)
(3) Antioxidant activity and protecting health effects of common medicinal plants.
(4) Oxidative stress, chronic disease, and muscle wasting by Moylan JS1, Reid M. (PubMed)
Saturday, December 3, 2022
Fennel Essential Oil and Extract, The Potent Anti Hypoglycemic Remedies, Scientists Reveal
Fennel may process a strong effect in preventing the abnormal rise of blood glucose in patients with diabetes, some scientists found.
In comparison to hyperglycemia with an excessive amount of glucose that circulates in the blood plasma, hypoglycemia is a condition of blood sugar, that falls below the levels of the normal range.
Patients with acute hypoglycemia may experience symptoms of clumsiness, trouble talking, confusion, loss of consciousness, seizures, or death.
Most cases of hyperglycemia in patients with diabetes are due to poor management. However, eating more carbohydrates than usual, less physical activity compared to a normal day being sick or high levels of stress in patients with diabetes also can cause blood glucose uptake.
Some researchers suggested that not getting the right dosage of insulin and glucose-lowering medication also causes increased blood glucose levels.
Long-term untreated hyperglycemia can elevate the onset of some serious complications including nerve damage, kidney damage and failure, heart disease, and eye disease, particularly in food and skin problems. or retinopathy foot problems caused by damaged nerves and poor blood flow skin problems, such as bacterial and fungal infections
Fennel (Foeniculum vulgare) is a plant species belongings to the family Apiaceae (Umbelliferae), native to the Mediterranean
The plant has been used in traditional and herbal medicine as a warming, carminative, antispasmodic, and antidepression agent and to stimulate the appetite, ease indigestion, soothe coughing, reduce intestinal spasms, regulate the menstrual cycle and relieve PMS,...
In the examine the antihyperglycemic activity of fennel essential oil in an animal model, researchers launched an investigation to evaluate rats induced by bacterial streptozotocin.
At the concentrations of 30 mg/kg body weight, the essential oil of fennel demonstrated a correction of hyperglycemia in the doses from 162.5 mg/dL to 81.97 ± 1.97 mg/dL by increasing the serum of antioxidants activity of serum glutathione peroxidase from 59.72 U/g Hb to 99.60 U/g Hb produced by the host.
The application also improved the pathological changes noticed in their kidney and pancreas, compared to the control group.
After making the final adjustment, researchers suggested that the study not only reaffirms the use of the essential oil of fennel for the treatment of hyperglycemia in folk medicine but also raises the possibility of essential oil inclusion in the antidiabetic drug industry.
Further analysis of the ethanolic and aqueous extracts of selected Sudanese plants, including fennel that is traditionally used to treat diabetes, researchers at the Khartoum College of Medical Sciences, suggested that fennel extract reveals a significant antioxidant activity in DPPH free radical scavenging assay.
However, the injection of fennel extract exhibited the highest toxicity.
These findings indicated that although fennel extract processes a substantial and positive effect in reducing the spike of blood glucose intake and the use of the fennel extract can only be prescribed by herbalists and professionals in the related field.
Additionally, in the testing, the hypoglycemic effect of a single dose of Gluconorm-5 (150, 300, and 600 mg/kg body weight) made up of five plants namely Camellia sinensis, Punica granatum, Macrotyloma uniflorum, Foeniculum vulgare and Trigonella foenum-graecum in normal, glucose loaded normal and diabetes-induced rats, researchers found that
* Fifteen days of oral feeding of the Gluconorm-5 (300 and 600 mg/kg) to diabetic rats resulted in a significant (P < 0.01) reduction of blood glucose, lipid profile, liver weight, and marker enzymes as compared to those rats in whom STZ induced toxicity was untreated.
* The diabetic rats treated with the formula showed expanded islets compared to the untreated diabetic rats, which showed shrunken islets.
* Treated rats received 300 mg/kg of Gluconorm-5 showed pronounced antidiabetic, antihyperlipidemic, and hepatoprotective effects.
This comprehensive differentiation showed that Gluconorm-5 processes potent antidiabetic antihyperlipidemic and hepatoprotective effect properties.
Taken altogether, fennel extract, and fennel essential oil used alone or combined with other herbal antidiabetic herbal medicine can be considered an adjuvant in the treatment of hyperglycemia and diabetes mellitus.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals' Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Foeniculum vulgare Mill: A Review of Its Botany, Phytochemistry, Pharmacology, Contemporary Application, and Toxicology by Shamkant B. Badgujar,* Vainav V. Patel, and Atmaram H. Bandivdekar(PMC)
(2) A study of antioxidant activity, enzymatic inhibition and in vitro toxicity of selected traditional Sudanese plants with anti-diabetic potential by Hilmi Y1, Abushama MF, Abdalgadir H, Khalid A, Khalid H(PubMed)
(3) The Dietary Furocoumarin Imperatorin Increases Plasma GLP-1 Levels in Type 1-Like Diabetic Rats by Wang LY1,2,3, Cheng KC4, Li Y5,6, Niu CS7, Cheng JT8,9, Niu HS(PubMed)
(4) Antidiabetic antihyperlipidemic and hepato-protective effect of Gluconorm-5: A polyherbal formulation in steptozotocin induced hyperglycemic rats by Gengiah K1, Hari R2, Anbu J(PubMed)
Sunday, November 27, 2022
#Herbal Ashwagandha Reduces the Risk of Memory Loss, Studies Find
Memory is one of the major functions of the brain that collects and stores data or information which is retrieved when needed.
In other words, memory is the retention of information over time that have a strong influence on future action.
Memory impairment is a condition of partial or complete loss of memory, depending on the quality of the neuron that has been affected.
Memory impairment other than the physical impact is a progressive disease that can lead to permanent loss of memory due to the gradual loss of neurons in the brain.
Memory impairment can be acute or chronic.
In acute impairment, memory is temporary loss in most cases associated with physical impact on the brain that causes injury of neurons.
Chronic memory impairment is the loss of memory that can get worse overtime found mostly in the elderly with neurodegenerative diseases, such as dementia.
In elderly or aging-induced memory loss is associated with the deterioration of a region of the brain involved in the formation and retrieval of memories, the hippocampus, and the reduced hormones and protein that protect and repair brain cells and stimulate neural growth.
The most common risk factors associated with memory loss in the general population are long-term use of certain medications, excessive alcohol drinking, smoking, drug abuse, depression, nutrient deficiency, stroke, and daily stress.
However, some researchers suggested the rise of memory impairment in the elderly probably is correlated to the promotion of the Western diet over the past few decades.
Dr. Scott E. Kanoski, the lead scientist in the review of the risk cognitive impairment in the Western diet consumption wrote, "Intake of saturated fats and simple carbohydrates, two of the primary components of a modern Western diet, is linked with the development of obesity and Alzheimer's Disease".
And, "Western diet intake is associated with cognitive impairment, with a specific emphasis on learning and memory functions that are dependent on the integrity of the hippocampus".
The results clearly stated if you are a Western diet follower, you are at a higher risk of memory impairment compared to healthy diet individuals.
Ashwagandha also is known as Withania somnifera is a nightshade plant in the genus of Withania, belonging to the family Solanaceae, native to the dry parts of India, North Africa, Middle East, and the Mediterranean. The herbal medicine has been considered as Indian ginseng and used in Ayurvedic medicine over 3000 years to treat tumors and tubercular glands, carbuncles, memory loss, and ulcers and considered as anti-stress, cognition-facilitating, anti-inflammatory, and anti-aging herbal medicine.
On finding a potent compound for the treatment of brain health, researchers examined the efficacy and safety of ashwagandha (Withania somnifera (L.) Dunal) on memory and cognitive functioning in adults with mild cognitive impairment (MCI).
The prospective, randomized, double-blind, placebo-controlled study included 50 adults assigned to the treatment of either ashwagandha-root extract (300 mg twice daily) or placebo for eight weeks.
According to the analysis of Wechsler Memory Scale III subtest scores for logical memory, at week 8, the ashwagandha treatment group exerted significant improvements in both immediate and general memory, compared with the placebo group.
Futhermore, verbal paired associates I (p = 0.042), faces I (p = 0.020), family pictures I (p = 0.006), logical memory II (p = 0.006) scores were also significantly increase compared to placebo.
According to the scores of Eriksen Flanker task (p = 0.002), Wisconsin Card Sort test (p = 0.014), Trail-Making test part A (p = 0.006), and the Mackworth Clock test (p = 0.009), ashwagandha treatment group also displayed a significantly greater improvement in executive function, sustained attention, and information-processing speed also compared to placebo.
Based on the findings, researchers said, "Ashwagandha may be effective in enhancing both immediate and general memory in people with MCI as well as improving executive function, attention, and information processing speed.".
Taken altogether, Ashwagandha may be considered a functional herb for the improvement of the brain health, pending the result of larger sample size and multicenter study
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Efficacy and Safety of Ashwagandha (Withania somnifera (L.) Dunal) Root Extract in Improving Memory and Cognitive Functions by Choudhary D1, Bhattacharyya S2, Bose S. (PubMed)
(2) Western Diet Consumption and Cognitive Impairment: Links to Hippocampal Dysfunction and Obesity by Scott E. Kanoski1 and Terry L. Davidson. (PMC)
In other words, memory is the retention of information over time that have a strong influence on future action.
Memory impairment is a condition of partial or complete loss of memory, depending on the quality of the neuron that has been affected.
Memory impairment other than the physical impact is a progressive disease that can lead to permanent loss of memory due to the gradual loss of neurons in the brain.
Memory impairment can be acute or chronic.
In acute impairment, memory is temporary loss in most cases associated with physical impact on the brain that causes injury of neurons.
Chronic memory impairment is the loss of memory that can get worse overtime found mostly in the elderly with neurodegenerative diseases, such as dementia.
In elderly or aging-induced memory loss is associated with the deterioration of a region of the brain involved in the formation and retrieval of memories, the hippocampus, and the reduced hormones and protein that protect and repair brain cells and stimulate neural growth.
The most common risk factors associated with memory loss in the general population are long-term use of certain medications, excessive alcohol drinking, smoking, drug abuse, depression, nutrient deficiency, stroke, and daily stress.
However, some researchers suggested the rise of memory impairment in the elderly probably is correlated to the promotion of the Western diet over the past few decades.
Dr. Scott E. Kanoski, the lead scientist in the review of the risk cognitive impairment in the Western diet consumption wrote, "Intake of saturated fats and simple carbohydrates, two of the primary components of a modern Western diet, is linked with the development of obesity and Alzheimer's Disease".
And, "Western diet intake is associated with cognitive impairment, with a specific emphasis on learning and memory functions that are dependent on the integrity of the hippocampus".
The results clearly stated if you are a Western diet follower, you are at a higher risk of memory impairment compared to healthy diet individuals.
Ashwagandha also is known as Withania somnifera is a nightshade plant in the genus of Withania, belonging to the family Solanaceae, native to the dry parts of India, North Africa, Middle East, and the Mediterranean. The herbal medicine has been considered as Indian ginseng and used in Ayurvedic medicine over 3000 years to treat tumors and tubercular glands, carbuncles, memory loss, and ulcers and considered as anti-stress, cognition-facilitating, anti-inflammatory, and anti-aging herbal medicine.
On finding a potent compound for the treatment of brain health, researchers examined the efficacy and safety of ashwagandha (Withania somnifera (L.) Dunal) on memory and cognitive functioning in adults with mild cognitive impairment (MCI).
The prospective, randomized, double-blind, placebo-controlled study included 50 adults assigned to the treatment of either ashwagandha-root extract (300 mg twice daily) or placebo for eight weeks.
According to the analysis of Wechsler Memory Scale III subtest scores for logical memory, at week 8, the ashwagandha treatment group exerted significant improvements in both immediate and general memory, compared with the placebo group.
Futhermore, verbal paired associates I (p = 0.042), faces I (p = 0.020), family pictures I (p = 0.006), logical memory II (p = 0.006) scores were also significantly increase compared to placebo.
According to the scores of Eriksen Flanker task (p = 0.002), Wisconsin Card Sort test (p = 0.014), Trail-Making test part A (p = 0.006), and the Mackworth Clock test (p = 0.009), ashwagandha treatment group also displayed a significantly greater improvement in executive function, sustained attention, and information-processing speed also compared to placebo.
Based on the findings, researchers said, "Ashwagandha may be effective in enhancing both immediate and general memory in people with MCI as well as improving executive function, attention, and information processing speed.".
Taken altogether, Ashwagandha may be considered a functional herb for the improvement of the brain health, pending the result of larger sample size and multicenter study
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Efficacy and Safety of Ashwagandha (Withania somnifera (L.) Dunal) Root Extract in Improving Memory and Cognitive Functions by Choudhary D1, Bhattacharyya S2, Bose S. (PubMed)
(2) Western Diet Consumption and Cognitive Impairment: Links to Hippocampal Dysfunction and Obesity by Scott E. Kanoski1 and Terry L. Davidson. (PMC)
Tuesday, November 22, 2022
Ginger, the Natural Antibiotics Alternative Functional Spice
Ginger may be considered a natural antibiotics alternative for the treatment of Candida albicans overgrowth without inducing any side effects, some scientists suggested.
Candida albicans is an opportunistic pathogenic yeast formed part of the commensal gastrointestinal mycobiota.
Candida albicans overgrowth is the most prevalent cause of fungal infections in humans.
Epidemiological studies strongly suggested that long-term users of antibiotics that cause an imbalance of the gut microbiome, weakened immune system, unhealthy diet, and women who are pregnant and hormone imbalance of hormone near menstruation are susceptible to the onset of the condition.
If you experience symptoms of oral thrush, recurring genital or urinary tract infections, persistent digestive issues, or joint pain. particularly, in the skin and nail fungal infections, you may have a yeast infection.
Please check with your doctor to rule out the Candida albicans overgrowth possibility.
Dr. Carol A. Kumamoto in the research team of infectious diseases in the study "Inflammation and gastrointestinal Candida colonization" suggested that Candida albicans overgrowth can be caused by other medical conditions, associated with a digestive disorder.
In the study, the doctor wrote, "Recent studies, however, show that high-level Candida colonization is associated with several diseases of the gastrointestinal tract. Further, results from animal models argue that Candida colonization delays the healing of inflammatory lesions and that inflammation promotes colonization".
And, "Both inflammatory bowel disease and gastrointestinal Candida colonization are associated with elevated levels of the pro-inflammatory cytokine IL-17. Therefore, effects on IL-17 levels may underlie the ability of Candida colonization to enhance inflammation".
These results strongly suggested, inflammation flames the overgrowth of Candida colonization in return, the overgrowth of Candida albicans induces persistently low-grade inflammation.
Ginger (Zingiber officinale) or ginger root, the second superfood used for thousands of years by mankind, is the genus Zingiber, belonging to the family Zingiberaceae, native to Tamil.
The root has been used in traditional and Chinese medicine to treat dyspepsia, gastroparesis, constipation, edema, difficult urination, colic, etc.
With an aim to find the natural ingredient or whole food for the replacement of conventional antibiotics without inducing any effects, researchers at the Teikyo University Institute of Medical Mycology investigated the effect of ginger against infection caused by Candida albicans.
4 preparations of the essential oils of young and mature rhizomes, air-dried and steamed rhizomes, and seed rhizomes of Zingiber officinale Roscoe (ginger) were compared in the study.
* All ginger essential oils processed a significant anti-Candida Albicans activity.
* Essential oil from the seed and air-dried rhizomes, exerted the highest effect compared to other preparations.
* The seed and air-dried rhizomes essential oils also had a potent inhibitory activity compared to ginger oleoresins obtained by ethanol and hypercritical carbon dioxide extraction and essential oils of 5 other plants in the family Zingiberaceae.
According to the chemical constituents assay, [6]-shogaol was most active against filament formation and growth of C. Albicans, followed by citral and [6]-gingerol.
Furthermore, ginger oleoresin, especially that obtained by ethanol extraction, with a high [6]-gingerol content exhibited potent anti-growth of C. Albicans compared to essential oils of ginger and other Zingiberaceae plants.
Moreover, a vitro joint study by the Institute of Science and Technology, researchers launched an investigation to evaluate the antimicrobial activity of 2% chlorhexidine gel (CHX) isolated from ginger as an auxiliary chemical substance and intracanal medications on Candida albicans.
The study included 48 single-rooted human teeth randomly divided into four groups (n = 12), according to intracanal medications used: (1) Calcium hydroxide + apyrogenic saline solution (Ca(OH)2 + SS), (2) 20% ginger glycolic extract (GEN), (3) calcium hydroxide + 20% ginger glycolic extract (Ca(OH)2 + GEN), (4) apyrogenic SS (control).
At the end of the experiment, researchers found that
* CHX was effective in the complete elimination of E. coli and C. Albicans.
* ChX also significantly reduced and then completely eliminated E. faecalis after intracanal medication.
* All other applications also revealed a reduction of endotoxins, the outer membrane of the cell wall of Gram-negative bacteria.
In the final report, the research team concluded, "CHX and intracanal medication used were able to eliminate the microorganisms from the root canal; the endotoxins were reduced, yet not completely eliminated".
These results strongly suggested that ginger bioactive compound processes a significant antibacterial activity, particularly in those of C. Albicans.
Taken all together, there is no doubt that ginger may be considered a functional food for the prevention and combined with primary medicine for the treatment of yeast infection with no side effects.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals' Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Anti-Candida and radical scavenging activities of essential oils and oleoresins of Zingiber officinale Roscoe and essential oils of other plants belonging to the family Zingiberaceae by Takahashi M1, Inouye S, Abe S.(PubMed)
(2) Action of Chlorhexidine, Zingiber officinale, and Calcium Hydroxide on Candidaalbicans, Enterococcus faecalis, Escherichia coli, and Endotoxin in the Root Canals by Valera MC1, Oliveira SA2, Maekawa LE2, Cardoso FG3, Chung A2, Silva SF2, Carvalho CA2. (PubMed)
(3) Inflammation and gastrointestinal Candida colonization by Carol A. Kumamoto. (PMC)
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