Monday, November 19, 2018
How to Prevent Onset of Pulmonary Fibrosis Naturally
Green tea may have a therapeutic and positive effect to reduce risk and progression and treatment of pulmonary fibrosis, some scientists suggested.
Pulmonary fibrosis (PF) is a chronic and progressive condition of lung disease characterized by reduced numbers and increased stiffness of air sac in the lungs (alveoli), affecting the lung breathing function to provide enough oxygen into the bloodstream
Green tea is a precious drink processed numbers of health benefit known to almost everyone in Asia and the Western world.
In the evaluation of green tea extract efficacy in pulmonary fibrosis caused by direct injury due to overexpression of oxygen free radicals and inflammatory cells and fibroblasts in mice model with injection of Paraquat (0.3 mg/kg) into the right lungs of rats, after 2 weeks, then assigned the tested mice to group treated by green tea extract or non treatment groups and control group treated by saline, after assessment, researchers found that
* Nontreatment group exerts a significant expression of pulmonary fibrosis, observed by contents of light microscopic morphometry and hydroxyproline and overcapacity of ROS observed by the lipid peroxidation assay.
Light microscopic morphometry is a valuable technique in the analysis of precancerous lesions at the light and electron microscopic level, in this case, it is pulmonary fibrosis.
Further examination also discovered that non-treatment mice group displays a pronouncedly increased
levels of malondialdehyde (MDA), an indication of overexpression of free radicals in induction of oxidative stress caused by ROS chain reaction and endothelin (ET)-1, and prepro-ET-1 mRNA expression, a strong indication of the endothelium signals of vasoconstriction and local cellular growth and survival of air sac cells in the lungs (alveoli).
Malondialdehyde (MDA) is a marker of oxidative stress
Endothelin 1 (ET-1) is a potent vasoconstrictor
Compared to nontreatment and saline groups, green tea administered 1% GTE mixed with feed group shows a significant decrease in pulmonary fibrosis, along with decreases in MDA, ET-1, and prepro-ET-1 mRNA expression
The result suggested that green tea inhibitory oxidative activity in reduced expression of pulmonary fibrosis through the promoted production of antioxidants and antioxidants from the host restore the ratio of antioxidant and free radicals and decreased the facilitation of proinflammatory cytokines in precipitated damage and apoptosis of lung cells and fibroblasts.
Dr. Kim HR, the lead author, after taking into account other confounders said, "GTE inhibits paraquat-induced pulmonary fibrosis by suppression of oxidative stress and ET-1 expression".
Additional study of the neutrophils in the site of infection in initiated host defense and inflammation for pulmonary fibrosis development by the Medical School of Padova, revealed that application of green tea (-)epigallocatechin-3-gallate (EGCG) strongly inhibits neutrophil elastase by repressing the reactive oxygen species activity in the induction of apoptosis of activated neutrophils.
In vitro, administration of EGCG dramatically inhibited chemokine expression, secondary pro-inflammatory mediators induced by primary pro-inflammatory in activated neutrophil chemotaxis in the migration of neutrophils of the immune system to the site of infection.
Importantly, injection of green tea EGCG also demonstrated a significant effect by blocking neutrophil-mediated angiogenesis in vivo by the initiated growth of new blood vessels to stimulate and fuel the ongoing lung cell damage and death of the cell in the alveoli.
This differentiation constituted a substantial and protective effect in enhanced resolution in a pulmonary inflammation model and significantly reduced consequent fibrosis.
Dr. Donà M, at the end of the analysis, said, "These results provide molecular and cellular insights into the claimed beneficial properties of green tea and indicate that EGCG is a potent anti-inflammatory compound with therapeutic potential".
The above analysis of green tea effect in protect the lung against the development of pulmonary fibrosis caused by free radical chain reaction and overproduction of pro-inflammatory factors were supported by the study of "the protective effect of green tea extract (GTE), curcumin, against N-acetyl cysteine (NAC) on experimentally induced pulmonary fibrosis" by Cairo University.
According to the study, application of curcumin (200 mg/kg b.w), GTE (150 mg/kg b.w), and NAC (490 mg/kg b.w) orally for 14 days with concomitant administration of cyclophosphamide (CP), revealed a strong activity in inhibited oxidative stress and lung myeloperoxidase activity observed in animals of the CP group.
Cyclophosphamide is a chemo drug used to suppress the immune system.
Myeloperoxidase (MPO) is a highly oxidative enzyme.
Treatment group also decreased the levels of N-acetyl-β-d-glucosaminidase, leukotriene C₄, and protein in bronchoalveolar lavage fluid (BALF) in demonstration of overreaction of immune response in induction of inflammation through inhibited production of proinflammatory cytokines (growth factor-β, interleukin -1β, and histamine) in initiated lung injury and induced apoptosis of lung cells.
N-acetyl-beta-D-glucosaminidase) in the analysis of kidney disease including nephrotoxicity.
Leukotriene C₄ is a leukotriene produced and secreted by eosinophils on activation.
Bronchoalveolar lavage fluid (BALF) is used to analyze interstitial lung diseases.
Protein abundance levels in BALF is a marker of lung diseases
Taken together, green tea and its bioactive polyphenols may be considered a functional food for the prevention and treatment of pulmonary fibrosis through reducing oxidative stress and inflammatory effect in elevated risk and progression of the disease.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Loose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Home page http://kylejnorton.blogspot.ca
Kyle J. Norton (Scholar, Master of Nutrients, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.
Sources
(1) Neutrophil restraint by green tea: inhibition of inflammation, associated angiogenesis, and pulmonary fibrosis by Donà M1, Dell'Aica I, Calabrese F, Benelli R, Morini M, Albini A, Garbisa S.(PubMed)
(2) Green tea extract inhibits paraquat-induced pulmonary fibrosis by suppression of oxidative stress and endothelin-l expression by Kim HR1, Park BK, Oh YM, Lee YS, Lee DS, Kim HK, Kim JY, Shim TS, Lee SD(PubMed)
(3) Modulatory effects of curcumin and green tea extract against experimentally induced pulmonary fibrosis: a comparison with N-acetyl cysteine by Hamdy MA1, El-Maraghy SA, Kortam MA(PubMed)
Sunday, November 18, 2018
How to Cure Impetigo Naturally With No Adverse Effects
Green tea or tea lotion may have a therapeutic and positive effect better than conventional medicine Framycetin and Cephalexin gramicidin (soframycin) in the treatment of impetigo, some scientists suggested.
The disease investigation was differentiated by numbers of institutes including Baghdad University and the results of the studies were published in the online literature.
You can view the abstract of studies from PubMed, by clicking any of the resources' link.
Impetigo is a skin condition caused by bacterial skin infection with symptoms of blisters and sores,
around the nose and mouth, and on the arms or legs. In some case, it may appear in the facial area.
The disease infects mostly children.
In differentiated the effect of tea lotion against impetigo infected by bacteria, researchers at the Baghdad University conducted a study with participated of a total of 104 patients, including 47 females (45.2%) and 57 males (54.8%) with ages ranged from one month to 40 years with a median of 4 years.
Patients were randomly assigned to the treatment group with green tea applied to the infected areas and the control group.
According to the diagnosis from the swabbed collected from patients, and analyzed by microbiology impetigo contagiosa, pure S. aureus and the combination of S. aureus and Streptococcus pyogenes were presented in 94.3% and 5.7% respectively in all patients.
These results suggested that the prevalent risk of impetigo is mostly caused by the infection of S. aureus.
Application tea lotion, including green tea, demonstrated a significant effect in reduced infectious areas substantially with the successfully cured rate of 81.3% in compared to control non-treatment group.
In examining the 40 patients in control group further assigned to 2 groups received either an ointment containing Framycetin or gramicidin (soframycin), researchers found that Framycetin and cephalexin gramicidin (soframycin) exerted a potential a cure rate of only 72.2% and 78.6%, respectively.
The results suggested that tea ointment or lotion displayed a better effect in treating impetigo in compared to conventional medicine Framycetin and gramicidin (soframycin) without inducing any adverse effects.
Dr. Sharquie KE, after taking into account of other co and confounders said, "(tea lotion) demonstrated the anti-bacterial action of crude tea in vivo, against impetigo contagiosa".
In further evaluation of green tea effect in reduced prevalence of skin infection, researchers at the Oakland University William Beaumont School of Medicine Rochester showed that catechins found in green tea have shown promise for having antimicrobial effects, particular in fractions of (-)-epicatechin (EC), (-)-epicatechin-3-gallate (ECG), (-)-epigallocatechin (EGC), and (-)-epigallocatechin-3-gallate (EGCG).
Researchers continued, application of green tea bioactive catechin exhibited a variety of antimicrobial mechanisms and may be considered as a potential for preventive and therapeutic purposes.
In fact, relatively low concentrations of ECG was found to sensitize methicillin-resistant S. aureus (MRSA) clinical isolates to levels of oxacillin.
And, Catechin gallates such as ECG also showed to intercalate into phospholipid bilayers, affecting both virulence and antibiotic resistance by perturbing the function of the bacterial process of invasion.
The results may be attributed to green tea effect in reduced key processes associated with the bacterial cytoplasmic membrane.
However, further data collection on studies performed with human consumption during the course of infections, and studies on the occurrence of infections in populations that consume regular amounts of green tea will be necessary to complete the picture of its antimicrobial possibilities.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) The antibacterial activity of tea in vitro and in vivo (in patients with impetigo contagiosa).
Sharquie KE1, al-Turfi IA, al-Salloum SM. (PubMed)
(2) Antimicrobial properties of green tea catechins by Taylor PW1, Hamilton-Miller JM, Stapleton PD. (PubMed)
(3) The antimicrobial possibilities of green tea by Reygaert WC1.(PubMed)
The disease investigation was differentiated by numbers of institutes including Baghdad University and the results of the studies were published in the online literature.
You can view the abstract of studies from PubMed, by clicking any of the resources' link.
Impetigo is a skin condition caused by bacterial skin infection with symptoms of blisters and sores,
around the nose and mouth, and on the arms or legs. In some case, it may appear in the facial area.
The disease infects mostly children.
In differentiated the effect of tea lotion against impetigo infected by bacteria, researchers at the Baghdad University conducted a study with participated of a total of 104 patients, including 47 females (45.2%) and 57 males (54.8%) with ages ranged from one month to 40 years with a median of 4 years.
Patients were randomly assigned to the treatment group with green tea applied to the infected areas and the control group.
According to the diagnosis from the swabbed collected from patients, and analyzed by microbiology impetigo contagiosa, pure S. aureus and the combination of S. aureus and Streptococcus pyogenes were presented in 94.3% and 5.7% respectively in all patients.
These results suggested that the prevalent risk of impetigo is mostly caused by the infection of S. aureus.
Application tea lotion, including green tea, demonstrated a significant effect in reduced infectious areas substantially with the successfully cured rate of 81.3% in compared to control non-treatment group.
In examining the 40 patients in control group further assigned to 2 groups received either an ointment containing Framycetin or gramicidin (soframycin), researchers found that Framycetin and cephalexin gramicidin (soframycin) exerted a potential a cure rate of only 72.2% and 78.6%, respectively.
The results suggested that tea ointment or lotion displayed a better effect in treating impetigo in compared to conventional medicine Framycetin and gramicidin (soframycin) without inducing any adverse effects.
Dr. Sharquie KE, after taking into account of other co and confounders said, "(tea lotion) demonstrated the anti-bacterial action of crude tea in vivo, against impetigo contagiosa".
In further evaluation of green tea effect in reduced prevalence of skin infection, researchers at the Oakland University William Beaumont School of Medicine Rochester showed that catechins found in green tea have shown promise for having antimicrobial effects, particular in fractions of (-)-epicatechin (EC), (-)-epicatechin-3-gallate (ECG), (-)-epigallocatechin (EGC), and (-)-epigallocatechin-3-gallate (EGCG).
Researchers continued, application of green tea bioactive catechin exhibited a variety of antimicrobial mechanisms and may be considered as a potential for preventive and therapeutic purposes.
In fact, relatively low concentrations of ECG was found to sensitize methicillin-resistant S. aureus (MRSA) clinical isolates to levels of oxacillin.
And, Catechin gallates such as ECG also showed to intercalate into phospholipid bilayers, affecting both virulence and antibiotic resistance by perturbing the function of the bacterial process of invasion.
The results may be attributed to green tea effect in reduced key processes associated with the bacterial cytoplasmic membrane.
However, further data collection on studies performed with human consumption during the course of infections, and studies on the occurrence of infections in populations that consume regular amounts of green tea will be necessary to complete the picture of its antimicrobial possibilities.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) The antibacterial activity of tea in vitro and in vivo (in patients with impetigo contagiosa).
Sharquie KE1, al-Turfi IA, al-Salloum SM. (PubMed)
(2) Antimicrobial properties of green tea catechins by Taylor PW1, Hamilton-Miller JM, Stapleton PD. (PubMed)
(3) The antimicrobial possibilities of green tea by Reygaert WC1.(PubMed)
Saturday, November 17, 2018
Infectious Diseases: Carrot, The Tasty Food That Gobbles Up Pathogenic Microorganisms, Scientists Reveal
Carrots may have a profound and positive effect in gobbled up foreign microbial organisms before they can cause infection and damage to the host tissue, some scientists suggested.
The results of the veggie inhibition of mycobacterial expression in increased risk of infection were demonstrated by respectable institutes, including Iowa State University and Université de Monastir.
Infectious tissue caused by microbial organisms can induce transmissible disease or communicable disease through the production of toxins.
Most common symptoms of infection are a fever. This is the result of the reaction of the immune response in stimulated overproduction of pro-inflammatory cytokines in protection the damage or injury against micro pathogens.
However, over repression of pro-inflammatory factors can also induce tissue damage and forming of scars.
Other common symptoms also include chills and sweats, cough, sore throat, nasal congestion,....and burning or pain with urination
Some researchers suggested that most people with a balance of antioxidant, produced by tissue enzyme and free radicals are normally performed quite well against microorganisms during the time of infection.
Unluckily, people with a weakened immune system caused by reduced levels of antioxidant enzymes may need to gobble up some anti-inflammatory agents to speed up the recovery.
Conventional antibiotics may be helpful, however, they can cause severe adverse effects.
Carrot, a root vegetable with an orange color is a subspecies of Daucus carota, belongings to the family Apiaceae, native to Asian and Europe.
Nutrients
1. Carbohydrates
2. Sugars
3. Fibre
4. Fat
5. Protein
6. Vitamin A
7. Thiamine (VittaminB1)
8. Riboflavin (Vittamin B2)
9. Niacin (Vittamin B3)
10. Vitamin B6
11. Folate (Vittamin B9)
12. Vitamin C
13. Vitamin K
14. Calcium
15. Iron
16. Magnesium
17. Molybdenum
18. Phosphorus
19. Potassium
20. Sodium
In the investigate the effect of essential oils extracted from Daucus carota L. (Apiaceae) seeds in inhibited the spread of microbial organism through comparison of 4 volatile compounds β-bisabolene (mean content of 39.33%), sabinene (8.53%), geranyl acetate (7.12%), and elemicin (6.26%), researchers found that application of all compounds exert strong activity in inhibited expression of Gram-positive (Staphylococcus aureus) and two Gram-negative bacteria (Escherichia coli and Salmonella typhimurium).
The result of efficacy probably was due to carrot seed extract's protection of cell membrane against micro organism in initiated cell infection
Nornally, infectious agents invade cell membrane as the entry point to alternate DNA of the healthy cells.
In vitro, injection of all major compounds also showed a potential effect against Candida albicans, a pathogenic yeast.
Further more, essential oil of carrot seed extract also exerted a similar antibacterial and antifungal activities in compared to the individual compound.
Some researchers suggested that antioxidant may also have a profound effect in the initiated expression of free radical cytotoxicity in facilitating the damage and death of microorganims, particularly in the infectious cells.
Interestingly, the precipitated cytotoxicity induced by reactive oxygen species and carrot antioxidant did not cause harm to the healthy cells.
Also, the expression of antioxidant in the found compound ameliorated the immune response to protect our body against the stimulation of microorganism in the initiated production of inflammatory cytokine without reduced immune activity.
Over expression of proinflammation not only associated to increase symptoms of swelling, pain, fever but also the risk of cell damage and apoptosis in the site of infection, leading to the abnormal healing skin.
Additionally, in the analysis of the carrot essential oil from flowers and roots of Daucus carota L. ssp. maritimus obtained by hydrodistillation, researchers at the Université de Monastir reported that out of thirty-two and six compounds were identified in flower and root oils, phenolic derivatives (76.3%), myristicin (31; 29.7%), and dillapiole (32; 46.6%) constituted to main fraction demonstrated most protective effect in the inhibition of a series of common human pathogenic bacteria.
According to the minimum inhibitory concentration (MIC) and the minimum bactericidal concentration (MBC) assays, the found chemical compound also inhibited some clinically and environmentally isolated strains.
The findings suggested that carrot with abundant bioactive compounds may be used as a functional food for reduced risk and treatment of mycobacterial infection.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Variation of the chemical composition and antimicrobial activity of the essential oils of natural populations of Tunisian Daucus carota L. (Apiaceae) by Rokbeni N1, M'rabet Y, Dziri S, Chaabane H, Jemli M, Fernandez X, Boulila A.(PubMed)
(2) Flower and root oils of the tunisian Daucus carota L. ssp. maritimus (Apiaceae): integrated analyses by GC, GC/MS, and 13C-NMR spectroscopy, and in vitro antibacterial activity by Jabrane A1, Jannet HB, Harzallah-Skhiri F, Mastouri M, Casanova J, Mighri Z.(PubMed)
The results of the veggie inhibition of mycobacterial expression in increased risk of infection were demonstrated by respectable institutes, including Iowa State University and Université de Monastir.
Infectious tissue caused by microbial organisms can induce transmissible disease or communicable disease through the production of toxins.
Most common symptoms of infection are a fever. This is the result of the reaction of the immune response in stimulated overproduction of pro-inflammatory cytokines in protection the damage or injury against micro pathogens.
However, over repression of pro-inflammatory factors can also induce tissue damage and forming of scars.
Other common symptoms also include chills and sweats, cough, sore throat, nasal congestion,....and burning or pain with urination
Some researchers suggested that most people with a balance of antioxidant, produced by tissue enzyme and free radicals are normally performed quite well against microorganisms during the time of infection.
Unluckily, people with a weakened immune system caused by reduced levels of antioxidant enzymes may need to gobble up some anti-inflammatory agents to speed up the recovery.
Conventional antibiotics may be helpful, however, they can cause severe adverse effects.
Carrot, a root vegetable with an orange color is a subspecies of Daucus carota, belongings to the family Apiaceae, native to Asian and Europe.
Nutrients
1. Carbohydrates
2. Sugars
3. Fibre
4. Fat
5. Protein
6. Vitamin A
7. Thiamine (VittaminB1)
8. Riboflavin (Vittamin B2)
9. Niacin (Vittamin B3)
10. Vitamin B6
11. Folate (Vittamin B9)
12. Vitamin C
13. Vitamin K
14. Calcium
15. Iron
16. Magnesium
17. Molybdenum
18. Phosphorus
19. Potassium
20. Sodium
In the investigate the effect of essential oils extracted from Daucus carota L. (Apiaceae) seeds in inhibited the spread of microbial organism through comparison of 4 volatile compounds β-bisabolene (mean content of 39.33%), sabinene (8.53%), geranyl acetate (7.12%), and elemicin (6.26%), researchers found that application of all compounds exert strong activity in inhibited expression of Gram-positive (Staphylococcus aureus) and two Gram-negative bacteria (Escherichia coli and Salmonella typhimurium).
The result of efficacy probably was due to carrot seed extract's protection of cell membrane against micro organism in initiated cell infection
Nornally, infectious agents invade cell membrane as the entry point to alternate DNA of the healthy cells.
In vitro, injection of all major compounds also showed a potential effect against Candida albicans, a pathogenic yeast.
Further more, essential oil of carrot seed extract also exerted a similar antibacterial and antifungal activities in compared to the individual compound.
Some researchers suggested that antioxidant may also have a profound effect in the initiated expression of free radical cytotoxicity in facilitating the damage and death of microorganims, particularly in the infectious cells.
Interestingly, the precipitated cytotoxicity induced by reactive oxygen species and carrot antioxidant did not cause harm to the healthy cells.
Also, the expression of antioxidant in the found compound ameliorated the immune response to protect our body against the stimulation of microorganism in the initiated production of inflammatory cytokine without reduced immune activity.
Over expression of proinflammation not only associated to increase symptoms of swelling, pain, fever but also the risk of cell damage and apoptosis in the site of infection, leading to the abnormal healing skin.
Additionally, in the analysis of the carrot essential oil from flowers and roots of Daucus carota L. ssp. maritimus obtained by hydrodistillation, researchers at the Université de Monastir reported that out of thirty-two and six compounds were identified in flower and root oils, phenolic derivatives (76.3%), myristicin (31; 29.7%), and dillapiole (32; 46.6%) constituted to main fraction demonstrated most protective effect in the inhibition of a series of common human pathogenic bacteria.
According to the minimum inhibitory concentration (MIC) and the minimum bactericidal concentration (MBC) assays, the found chemical compound also inhibited some clinically and environmentally isolated strains.
The findings suggested that carrot with abundant bioactive compounds may be used as a functional food for reduced risk and treatment of mycobacterial infection.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Variation of the chemical composition and antimicrobial activity of the essential oils of natural populations of Tunisian Daucus carota L. (Apiaceae) by Rokbeni N1, M'rabet Y, Dziri S, Chaabane H, Jemli M, Fernandez X, Boulila A.(PubMed)
(2) Flower and root oils of the tunisian Daucus carota L. ssp. maritimus (Apiaceae): integrated analyses by GC, GC/MS, and 13C-NMR spectroscopy, and in vitro antibacterial activity by Jabrane A1, Jannet HB, Harzallah-Skhiri F, Mastouri M, Casanova J, Mighri Z.(PubMed)
Friday, November 16, 2018
Herbal Alfalfa,The Anti-inflammatory Diseases Natural Whole Food and Plant
The efficacy of botany in the use of plants for treatment and cure diseases with little or no side effects have drawn interest in today conscientious scientists, since the discovery of aspirin (from willow bark), quinine (from cinchona bark), and morphine (from the opium poppy)...
However, the development of synthetic single medicine for treating diseases is not beneficial to patients but profits to the big pharmaceutical companies symptoms.
The use of conventional medicine for the treatment of one disease is found to induce serious side effects in the short term and serious complications in the long-term.
Examples
* Intake of aspirin may facilitate symptoms of black, bloody, or tarry stools; coughing up blood, severe nausea, vomiting,........ and stomach pain. Long-term use of the medicine can cause stroke as a result of burst blood vessels,.... and gastrointestinal bleeding.
* Administration of quinine can induce serious symptoms of fever, chills, confusion, weakness, sweating; severe vomiting, stomach pain,.... and diarrhea chest pain. And long-term intake can induce trouble breathing, severe dizziness, fainting, fast or pounding heartbeats,.... and problems with vision or hearing.
Inflammation is a natural process of immune reaction that protest our body against infection and injury. Overexpression of inflammatory substances produced by the immune system may cause the localized physical condition of reddened, swollen, hot, and often painful. However, in some cases, over the presence of pro-inflammatory cytokines can induce cytotoxicity that damages healthy cells and tissue.
According to the free dictionary by Farlex(4), there are 3 major components that make up the state of acute inflammation, including
* Changes in the caliber of blood vessels and the rate of blood flow through them (hemodynamic changes)
* Increased capillary permeability, and
* Leukocytic exudation.
And chronic inflammation may be a slow onset but it is characterized by persistent inflammation and lack of clear resolution as the infectious tissues and cells are no longer able to overcome the effects caused by the injuring agents.
Chronic inflammation can eventually cause several diseases and conditions, including some cancers, autoimmune diseases,....... and rheumatoid arthritis.
Alfalfa, a botany plant may be used to modulate immune response for treatment of acute inflammation and diseases associated with chronic inflammation, some scientists suggested.
Alfalfa is a flowering plant in the genus Medicago, belonging to the family Fabaceae, cultivated all over the world as hay for cattle feeding.
The herbal plant has been used in traditional medicine over thousands of year to treat high cholesterol, asthma, osteoarthritis, rheumatoid arthritis, diabetes, enhanced digestive system, bleeding disorder, kidney, and urinary tract infection, etc.
North American aboriginals have used Alfalfa seed as food in making bread and mush.
According to studies, alfalfa expressed significant anti-inflammatory effect through the inhibiting production of pro-inflammatory cytokines during injury, foreign invasion, and free radical domino's action, etc....
The University of Maryland study of novel pectic polysaccharide from alfalfa(Medicago sativa L.) stem, suggested that the phytochemicals isolated from alfalfa exert significant anti-inflammatory effect against mRNA expressions of the pro-inflammatory cytokine genes, especially for IL-1β antibody(1).
IL-1β is a pro-inflammatory cytokine that used the major source of macrophages in response to the early stage of inflammation.
Chronic inflammatory expression of human IL-1β is associated with gastric inflammation and tumorigenesis in stomachs of studies mice.
The chloroform extract of alfalfa aerial part also inhibited the function of lipopolysaccharide (LPS) of Gram-negative bacteria in stimulated immune responses in induced inflammation and suppressed LPS-mediated activation of the extracellular signal-regulated the proinflammatory and prothrombotic responses of nuclear factor kappa-B pathway(2).
Dr. Toby Lawrence, in the evaluation of "The Nuclear Factor NF-κB Pathway in Inflammation" said, "The nuclear factor NF-κB pathway has long been considered a prototypical proinflammatory signaling pathway, largely based on the role of NF-κB in the expression of proinflammatory genes including cytokines, chemokines, and adhesion molecules" and " NF-κB has long been considered the “holy grail” as a target for new anti-inflammatory drugs"(6).
The cinnamic acid derivatives and fatty acids active constituents of the extract were also effective in ameliorated inflammation and immune response through inhibition of nitric oxide (NO), tumor necrosis factor (TNF-α), and prostaglandin E2 (PGE2) involved in the development of inflammatory diseases(3).
Nitric oxide (NO), plays a duo role in the pathogenesis of inflammation as anti-inflammatory cytokine under normal physiological conditions. However, the molecule also acts as a pro-inflammatory mediator in abnormal situations.
Tumor necrosis factor (TNF-α), a key regulator of the inflammatory response, plays an important role in the regulation of cellular responses, which include cell death, survival, differentiation, proliferation, and migration by stimulating a change of vascular endothelial cells in expression of pro-inflammation.
Prostaglandin E2 (PGE2) may function in both the promotion and resolution of inflammation.
However, under the abnormal condition such as persistent tissue damage, the hormone may contribute to the up-regulation of the pro-inflammatory cytokines.
Taking together, alfalfa no doubt has processed anti-inflammatory effects through inhibited free radicals, proinflammatory cytokines and hormone that involve the development of inflammatory and autoimmune diseases.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Structural, thermal, and anti-inflammatory properties of a novel pectic polysaccharide from alfalfa(Medicago sativa L.) stem by Chen L, Liu J, Zhang Y, Dai B, An Y, Yu LL1. (PubMed)
(2) Chloroform extract of alfalfa (Medicago sativa) inhibits lipopolysaccharide-induced inflammation by downregulating ERK/NF-κB signaling and cytokine production by Choi KC1, Hwang JM, Bang SJ, Kim BT, Kim DH, Chae M, Lee SA, Choi GJ, Kim DH, Lee JC. (PubMed)
(3) Anti-Inflammatory Activities of Cinnamomum cassiaConstituents In Vitro and In Viv by Jung-Chun Liao,1 Jeng-Shyan Deng,2 Chuan-Sung Chiu,3,4. (HindaWi)
(4) Acute inflammation, the free dictionary by Farlex
(5) IL-1β by Science Direct
(6) The Nuclear Factor NF-κB Pathway in Inflammation by Toby Lawrence. (PMC)
However, the development of synthetic single medicine for treating diseases is not beneficial to patients but profits to the big pharmaceutical companies symptoms.
The use of conventional medicine for the treatment of one disease is found to induce serious side effects in the short term and serious complications in the long-term.
Examples
* Intake of aspirin may facilitate symptoms of black, bloody, or tarry stools; coughing up blood, severe nausea, vomiting,........ and stomach pain. Long-term use of the medicine can cause stroke as a result of burst blood vessels,.... and gastrointestinal bleeding.
* Administration of quinine can induce serious symptoms of fever, chills, confusion, weakness, sweating; severe vomiting, stomach pain,.... and diarrhea chest pain. And long-term intake can induce trouble breathing, severe dizziness, fainting, fast or pounding heartbeats,.... and problems with vision or hearing.
Inflammation is a natural process of immune reaction that protest our body against infection and injury. Overexpression of inflammatory substances produced by the immune system may cause the localized physical condition of reddened, swollen, hot, and often painful. However, in some cases, over the presence of pro-inflammatory cytokines can induce cytotoxicity that damages healthy cells and tissue.
According to the free dictionary by Farlex(4), there are 3 major components that make up the state of acute inflammation, including
* Changes in the caliber of blood vessels and the rate of blood flow through them (hemodynamic changes)
* Increased capillary permeability, and
* Leukocytic exudation.
And chronic inflammation may be a slow onset but it is characterized by persistent inflammation and lack of clear resolution as the infectious tissues and cells are no longer able to overcome the effects caused by the injuring agents.
Chronic inflammation can eventually cause several diseases and conditions, including some cancers, autoimmune diseases,....... and rheumatoid arthritis.
Alfalfa, a botany plant may be used to modulate immune response for treatment of acute inflammation and diseases associated with chronic inflammation, some scientists suggested.
Alfalfa is a flowering plant in the genus Medicago, belonging to the family Fabaceae, cultivated all over the world as hay for cattle feeding.
The herbal plant has been used in traditional medicine over thousands of year to treat high cholesterol, asthma, osteoarthritis, rheumatoid arthritis, diabetes, enhanced digestive system, bleeding disorder, kidney, and urinary tract infection, etc.
North American aboriginals have used Alfalfa seed as food in making bread and mush.
According to studies, alfalfa expressed significant anti-inflammatory effect through the inhibiting production of pro-inflammatory cytokines during injury, foreign invasion, and free radical domino's action, etc....
The University of Maryland study of novel pectic polysaccharide from alfalfa(Medicago sativa L.) stem, suggested that the phytochemicals isolated from alfalfa exert significant anti-inflammatory effect against mRNA expressions of the pro-inflammatory cytokine genes, especially for IL-1β antibody(1).
IL-1β is a pro-inflammatory cytokine that used the major source of macrophages in response to the early stage of inflammation.
Chronic inflammatory expression of human IL-1β is associated with gastric inflammation and tumorigenesis in stomachs of studies mice.
The chloroform extract of alfalfa aerial part also inhibited the function of lipopolysaccharide (LPS) of Gram-negative bacteria in stimulated immune responses in induced inflammation and suppressed LPS-mediated activation of the extracellular signal-regulated the proinflammatory and prothrombotic responses of nuclear factor kappa-B pathway(2).
Dr. Toby Lawrence, in the evaluation of "The Nuclear Factor NF-κB Pathway in Inflammation" said, "The nuclear factor NF-κB pathway has long been considered a prototypical proinflammatory signaling pathway, largely based on the role of NF-κB in the expression of proinflammatory genes including cytokines, chemokines, and adhesion molecules" and " NF-κB has long been considered the “holy grail” as a target for new anti-inflammatory drugs"(6).
The cinnamic acid derivatives and fatty acids active constituents of the extract were also effective in ameliorated inflammation and immune response through inhibition of nitric oxide (NO), tumor necrosis factor (TNF-α), and prostaglandin E2 (PGE2) involved in the development of inflammatory diseases(3).
Nitric oxide (NO), plays a duo role in the pathogenesis of inflammation as anti-inflammatory cytokine under normal physiological conditions. However, the molecule also acts as a pro-inflammatory mediator in abnormal situations.
Tumor necrosis factor (TNF-α), a key regulator of the inflammatory response, plays an important role in the regulation of cellular responses, which include cell death, survival, differentiation, proliferation, and migration by stimulating a change of vascular endothelial cells in expression of pro-inflammation.
Prostaglandin E2 (PGE2) may function in both the promotion and resolution of inflammation.
However, under the abnormal condition such as persistent tissue damage, the hormone may contribute to the up-regulation of the pro-inflammatory cytokines.
Taking together, alfalfa no doubt has processed anti-inflammatory effects through inhibited free radicals, proinflammatory cytokines and hormone that involve the development of inflammatory and autoimmune diseases.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Structural, thermal, and anti-inflammatory properties of a novel pectic polysaccharide from alfalfa(Medicago sativa L.) stem by Chen L, Liu J, Zhang Y, Dai B, An Y, Yu LL1. (PubMed)
(2) Chloroform extract of alfalfa (Medicago sativa) inhibits lipopolysaccharide-induced inflammation by downregulating ERK/NF-κB signaling and cytokine production by Choi KC1, Hwang JM, Bang SJ, Kim BT, Kim DH, Chae M, Lee SA, Choi GJ, Kim DH, Lee JC. (PubMed)
(3) Anti-Inflammatory Activities of Cinnamomum cassiaConstituents In Vitro and In Viv by Jung-Chun Liao,1 Jeng-Shyan Deng,2 Chuan-Sung Chiu,3,4. (HindaWi)
(4) Acute inflammation, the free dictionary by Farlex
(5) IL-1β by Science Direct
(6) The Nuclear Factor NF-κB Pathway in Inflammation by Toby Lawrence. (PMC)
Thursday, November 15, 2018
The Anti Fungal Infection Whole Food
The finding of whole food medication by renowned scientists all over the world to replace the single ingredient of Western medicine with little or no side effect has been difficult due to no commercial benefits and patent right to producers.
Fungal infection is a common disease caused by overgrowth of fungus.
In other words, the immune system that protects the body against microorganisms has been overwhelming by the overgrowth of fungus.
People with a weakened immune system such as cancer treatment, frequent use of antibiotics are associated to increase the risk of fungal infection.
Patients with diabetes are also more prone to fungal infections. Fungal infection associated with diabetes include jock itch, athlete's foot,..... and ringworm.
Depending on the locations of infection, patients may experience symptoms of common peeling, cracking, scaling redness, blisters Itching,...... and burning sensation.
In women, signs of yeast infection may include itching and swelling around the vagina. burning sensations or pain during urination or intercourse,........ and unusual vaginal discharge.
In men, signs of yeast infection may include burning and itching around the head of the penis,
redness, and swelling, pain during urination or sex,..... small, rash-like bumps.
If you experience some of the signs and symptoms indicated above, you may be infected by yeast. Please check with your doctor as soon as possible.
If you are given topical creams, oral medicine or antifungal injection, please make sure you understand the common and serious of side effects before applying.
Garbanzo bean(Chickpea) and its bioactive phytochemicals may be considered as antifungal function food in prevention and treatment of overgrowth of fungal species, some scientists suggested.
Garbanzo bean also known as chickpea is an edible legume of genus Cicer and the family Fabaceae.
It is one of the earliest cultivated vegetables in mankind, native to the Middle East.
The joint study lead by the ICAR-Indian Agricultural Research Institute suggested chickpea with abundant bioactive compounds may be used along with the relevant antioxidant capacities as antifungal whole food, through the expression of defense-related enzymes like l-phenylalanine ammonia lyase, peroxidase and polyphenol oxidase(1).
Phenylalanine ammonia lyase is an enzyme that converts ammonia and trans-cinnamic acid involved proper function of the neuron(7).
Peroxidase and polyphenol oxidase are antioxidants that inhibit overexpression of free radicals.
According to the study by the All India Institute of Medical Sciences, in the emergence of epidemic fungal pathogenic resistance to current antifungal drugs, C-25 found in Garbanzo beans(Chickpea) not only processes an effective antimycotic but also antiproliferative agent against human oral cancer cells(2).
In support to the above, chickpea is found to exhibit inhibitory activity against Aspergillus flavus in a study conducted by the South China Normal University(3).
Taken altogether garbanzo bean(chickpea) may be considered a functional food for the prevention and treatment of fungal infection. People with a high risk of fungal infection may want to add a portion garbanzo bean(chickpea) which processes abundant bioactive compounds into a daily diet for preventive measure.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Development of Mesorhizobium ciceri-Based Biofilms and Analyses of Their Antifungal and Plant Growth Promoting Activity in Chickpea Challenged by Fusarium Wilt. by Das K1, Rajawat MVS1, Saxena AK1,2, Prasanna R1.(PubMed)
(2) Antifungal and antiproliferative protein from Cicer arietinum: a bioactive compound against emerging pathogens by Kumar S1, Kapoor V2, Gill K1, Singh K1, Xess I3, Das SN2, Dey S1(PubMed)
(3) Some 2S albumin from peanut seeds exhibits inhibitory activity against Aspergillus flavus by Duan XH1, Jiang R, Wen YJ, Bin JH.(PubMed)
(4) Antibacterial and antifungal activity of cicerfuran and related 2-arylbenzofurans and stilbenes by Aslam SN1, Stevenson PC, Kokubun T, Hall DR.(PubMed)
(5) Cicerarin, a novel antifungal peptide from the green chickpea byChu KT1, Liu KH, Ng TB.(PubMed)
(6) Cicerin and arietin, novel chickpea peptides with different antifungal potencies by Ye XY1, Ng TB, Rao PF.(PubMed)
(7) Effects of cinnamic acid on memory deficits and brain oxidative stress in streptozotocin-induced diabetic mice by Hemmati AA1, Alboghobeish S2, Ahangarpour A(PubMed).
Fungal infection is a common disease caused by overgrowth of fungus.
In other words, the immune system that protects the body against microorganisms has been overwhelming by the overgrowth of fungus.
People with a weakened immune system such as cancer treatment, frequent use of antibiotics are associated to increase the risk of fungal infection.
Patients with diabetes are also more prone to fungal infections. Fungal infection associated with diabetes include jock itch, athlete's foot,..... and ringworm.
Depending on the locations of infection, patients may experience symptoms of common peeling, cracking, scaling redness, blisters Itching,...... and burning sensation.
In women, signs of yeast infection may include itching and swelling around the vagina. burning sensations or pain during urination or intercourse,........ and unusual vaginal discharge.
In men, signs of yeast infection may include burning and itching around the head of the penis,
redness, and swelling, pain during urination or sex,..... small, rash-like bumps.
If you experience some of the signs and symptoms indicated above, you may be infected by yeast. Please check with your doctor as soon as possible.
If you are given topical creams, oral medicine or antifungal injection, please make sure you understand the common and serious of side effects before applying.
Garbanzo bean(Chickpea) and its bioactive phytochemicals may be considered as antifungal function food in prevention and treatment of overgrowth of fungal species, some scientists suggested.
Garbanzo bean also known as chickpea is an edible legume of genus Cicer and the family Fabaceae.
It is one of the earliest cultivated vegetables in mankind, native to the Middle East.
The joint study lead by the ICAR-Indian Agricultural Research Institute suggested chickpea with abundant bioactive compounds may be used along with the relevant antioxidant capacities as antifungal whole food, through the expression of defense-related enzymes like l-phenylalanine ammonia lyase, peroxidase and polyphenol oxidase(1).
Phenylalanine ammonia lyase is an enzyme that converts ammonia and trans-cinnamic acid involved proper function of the neuron(7).
Peroxidase and polyphenol oxidase are antioxidants that inhibit overexpression of free radicals.
According to the study by the All India Institute of Medical Sciences, in the emergence of epidemic fungal pathogenic resistance to current antifungal drugs, C-25 found in Garbanzo beans(Chickpea) not only processes an effective antimycotic but also antiproliferative agent against human oral cancer cells(2).
In support to the above, chickpea is found to exhibit inhibitory activity against Aspergillus flavus in a study conducted by the South China Normal University(3).
Taken altogether garbanzo bean(chickpea) may be considered a functional food for the prevention and treatment of fungal infection. People with a high risk of fungal infection may want to add a portion garbanzo bean(chickpea) which processes abundant bioactive compounds into a daily diet for preventive measure.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Development of Mesorhizobium ciceri-Based Biofilms and Analyses of Their Antifungal and Plant Growth Promoting Activity in Chickpea Challenged by Fusarium Wilt. by Das K1, Rajawat MVS1, Saxena AK1,2, Prasanna R1.(PubMed)
(2) Antifungal and antiproliferative protein from Cicer arietinum: a bioactive compound against emerging pathogens by Kumar S1, Kapoor V2, Gill K1, Singh K1, Xess I3, Das SN2, Dey S1(PubMed)
(3) Some 2S albumin from peanut seeds exhibits inhibitory activity against Aspergillus flavus by Duan XH1, Jiang R, Wen YJ, Bin JH.(PubMed)
(4) Antibacterial and antifungal activity of cicerfuran and related 2-arylbenzofurans and stilbenes by Aslam SN1, Stevenson PC, Kokubun T, Hall DR.(PubMed)
(5) Cicerarin, a novel antifungal peptide from the green chickpea byChu KT1, Liu KH, Ng TB.(PubMed)
(6) Cicerin and arietin, novel chickpea peptides with different antifungal potencies by Ye XY1, Ng TB, Rao PF.(PubMed)
(7) Effects of cinnamic acid on memory deficits and brain oxidative stress in streptozotocin-induced diabetic mice by Hemmati AA1, Alboghobeish S2, Ahangarpour A(PubMed).
Tuesday, November 13, 2018
The Root Veggie and Its Bio Active Compounds That Prevent Stroke
Carrots may have a profound and positive effect in reduced risk of stroke, some scientists suggested.
Stroke is a medical condition caused by reduced blood flow to the brain resulting in cell death due to the blocked artery (ischemic stroke) or the leaking or bursting of a blood vessel (hemorrhagic stroke).
There is a general belief that stroke is an accumulation over a long period of unhealthy diet with red meat and processed meats in induction of artery-clogging.
Some researchers suggested that increased intake of fruits and vegetables such as carrot accompanied with good fats such as salmon, tuna, and mackerel may have a substantial effect in reduced inflammation in the arteries, improved blood flow and decreased the chance of blood clots.
Sadly, stroke is one of the most common causes of death worldwide.
In the US, according to statistic, approximately 800,000 people suffer a stroke in which 600,000 of these are first attacks, and 185,000 are recurrent attacks. Nearly three-quarters of all strokes occur in people over the age of 65.
Carrot, a root vegetable with an orange color is a sub species of Daucus carota, belongings to the family Apiaceae, native to Asian and Europe.
In the review of literature published to understand more of the role of carotenoids as antioxidants in lowering stroke risk based on observational studies, researchers at the Isfahan University of Medical Sciences conducted a search with some important keywords, including (Carotenoids [MeSH] OR Carotenes [tiab] OR Carotene [tiab] OR "lycopene [Supplementary Concept]" [MeSH] OR lycopene [tiab] OR beta-Carotene [tiab]) AND (stroke [MeSH] OR stroke [tiab] OR "Cerebrovascular Accident" [tiab] OR "Cerebrovascular Apoplexy" [tiab] OR "Brain Vascular Accident" [tiab] OR "Cerebrovascular Stroke" [tiab]) AND ("oxidative stress" [MeSH] OR "oxidative stress"[tiab]).
The results of the searching of papers published between 2000 and 2017 suggested that
* High dietary intake of six main carotenoids (i.e., lycopene, <- and®-carotene, lutein, zeaxanthin, and astaxanthin) was associated with reduced risk of stroke due to their benefits in reduced overexpression of reactive oxygen species.
* Beyond the antioxidant activities in preventing free radical in the induction of chain reaction, other properties and mechanisms in ameliorated risk of stroke were not identified in studies sanctified the guideline and criteria.
These results suggested that dietary intake of six major carotenoids may be considered as stroke prevention and stroke mortality reduction.
Further in differentiation the benefits of lycopene a bioactive member in carotenoids, researchers found that intake of food containing a high amount of lycopene demonstrates a substantially reduced risk of stroke in compared to nontakers.
According to the assessment of pooled analysis of seven prospective studies, with 116,127 participants and 1,989 cases, frequent consumption of lycopene decreased stroke risk by 19.3%, after adjusting for confounding factors.
In gender and geographic analysis, researchers also stated that lycopene exerts a strong impact in preventing the onset of stroke, particularly in European and male gender.
Dr. the lead scientist said, " Duration of follow-up had no effect on the final results. There was no evidence of publication bias" and " Lycopene, especially circulating lycopene, is negatively associated with stroke risk".
Additionally, in the examine the hypothesis whether low serum levels of lycopene are associated with increased risk of acute coronary events and stroke in middle-aged men previously free of CHD and stroke, researchers launched an investigation of 725 men aged 46-64 years examined in 1991-3 in the Kuopio Ischaemic Heart Disease Risk Factor Study.
By December 1997, out of 725 patients, 41 men were found to have either a fatal or a non-fatal acute coronary event or a stroke.
According to the observation of a Cox' proportional hazard's model and after adjusting to examination years, age, systolic blood pressure and three nutritional factors (serum folate, beta-carotene, and plasma vitamin C), researchers found that all 41 men are in the lowest quarter of serum lycopene levels.
These results once again suggested that daily intake of lycopene-rich foods to increase the circulating lycopene plays an essential role in the prevented risk of atherosclerotic vascular events in middle-aged men previously free of CHD and stroke.
Truly, patients with lower levels of serum lycopene were found to had a 3.3-fold risk of acute coronary events or stroke in compared with the others.
Taken together, carrot with a high amount of bioactive carotenoids, especially lycopene may be considered as a functional food in reduced the prevalent risk of stroke.
People who are at the higher quarter of stroke risk may want to add a portion of carrot into their daily diet for preventive measure.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Carotenoids as Potential Antioxidant Agents in Stroke Prevention: A Systematic Review by Bahonar A1, Saadatnia M1, Khorvash F1, Maracy M2, Khosravi A(PubMed)
(2) Dietary and circulating lycopene and stroke risk: a meta-analysis of prospective studies by Li X1, Xu J2.(PubMed)
(3) Low serum lycopene concentration is associated with an excess incidence of acute coronary events and stroke: the Kuopio Ischaemic Heart Disease Risk Factor Study by Rissanen TH1, Voutilainen S, Nyyssönen K, Lakka TA, Sivenius J, Salonen R, Kaplan GA, Salonen JT.(PubMed)
(4) Healthy eating and stroke(Stroke Foundation)
(5) Stroke Statistics by The Internet Stroke center
Stroke is a medical condition caused by reduced blood flow to the brain resulting in cell death due to the blocked artery (ischemic stroke) or the leaking or bursting of a blood vessel (hemorrhagic stroke).
There is a general belief that stroke is an accumulation over a long period of unhealthy diet with red meat and processed meats in induction of artery-clogging.
Some researchers suggested that increased intake of fruits and vegetables such as carrot accompanied with good fats such as salmon, tuna, and mackerel may have a substantial effect in reduced inflammation in the arteries, improved blood flow and decreased the chance of blood clots.
Sadly, stroke is one of the most common causes of death worldwide.
In the US, according to statistic, approximately 800,000 people suffer a stroke in which 600,000 of these are first attacks, and 185,000 are recurrent attacks. Nearly three-quarters of all strokes occur in people over the age of 65.
Carrot, a root vegetable with an orange color is a sub species of Daucus carota, belongings to the family Apiaceae, native to Asian and Europe.
In the review of literature published to understand more of the role of carotenoids as antioxidants in lowering stroke risk based on observational studies, researchers at the Isfahan University of Medical Sciences conducted a search with some important keywords, including (Carotenoids [MeSH] OR Carotenes [tiab] OR Carotene [tiab] OR "lycopene [Supplementary Concept]" [MeSH] OR lycopene [tiab] OR beta-Carotene [tiab]) AND (stroke [MeSH] OR stroke [tiab] OR "Cerebrovascular Accident" [tiab] OR "Cerebrovascular Apoplexy" [tiab] OR "Brain Vascular Accident" [tiab] OR "Cerebrovascular Stroke" [tiab]) AND ("oxidative stress" [MeSH] OR "oxidative stress"[tiab]).
The results of the searching of papers published between 2000 and 2017 suggested that
* High dietary intake of six main carotenoids (i.e., lycopene, <- and®-carotene, lutein, zeaxanthin, and astaxanthin) was associated with reduced risk of stroke due to their benefits in reduced overexpression of reactive oxygen species.
* Beyond the antioxidant activities in preventing free radical in the induction of chain reaction, other properties and mechanisms in ameliorated risk of stroke were not identified in studies sanctified the guideline and criteria.
These results suggested that dietary intake of six major carotenoids may be considered as stroke prevention and stroke mortality reduction.
Further in differentiation the benefits of lycopene a bioactive member in carotenoids, researchers found that intake of food containing a high amount of lycopene demonstrates a substantially reduced risk of stroke in compared to nontakers.
According to the assessment of pooled analysis of seven prospective studies, with 116,127 participants and 1,989 cases, frequent consumption of lycopene decreased stroke risk by 19.3%, after adjusting for confounding factors.
In gender and geographic analysis, researchers also stated that lycopene exerts a strong impact in preventing the onset of stroke, particularly in European and male gender.
Dr. the lead scientist said, " Duration of follow-up had no effect on the final results. There was no evidence of publication bias" and " Lycopene, especially circulating lycopene, is negatively associated with stroke risk".
Additionally, in the examine the hypothesis whether low serum levels of lycopene are associated with increased risk of acute coronary events and stroke in middle-aged men previously free of CHD and stroke, researchers launched an investigation of 725 men aged 46-64 years examined in 1991-3 in the Kuopio Ischaemic Heart Disease Risk Factor Study.
By December 1997, out of 725 patients, 41 men were found to have either a fatal or a non-fatal acute coronary event or a stroke.
According to the observation of a Cox' proportional hazard's model and after adjusting to examination years, age, systolic blood pressure and three nutritional factors (serum folate, beta-carotene, and plasma vitamin C), researchers found that all 41 men are in the lowest quarter of serum lycopene levels.
These results once again suggested that daily intake of lycopene-rich foods to increase the circulating lycopene plays an essential role in the prevented risk of atherosclerotic vascular events in middle-aged men previously free of CHD and stroke.
Truly, patients with lower levels of serum lycopene were found to had a 3.3-fold risk of acute coronary events or stroke in compared with the others.
Taken together, carrot with a high amount of bioactive carotenoids, especially lycopene may be considered as a functional food in reduced the prevalent risk of stroke.
People who are at the higher quarter of stroke risk may want to add a portion of carrot into their daily diet for preventive measure.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Carotenoids as Potential Antioxidant Agents in Stroke Prevention: A Systematic Review by Bahonar A1, Saadatnia M1, Khorvash F1, Maracy M2, Khosravi A(PubMed)
(2) Dietary and circulating lycopene and stroke risk: a meta-analysis of prospective studies by Li X1, Xu J2.(PubMed)
(3) Low serum lycopene concentration is associated with an excess incidence of acute coronary events and stroke: the Kuopio Ischaemic Heart Disease Risk Factor Study by Rissanen TH1, Voutilainen S, Nyyssönen K, Lakka TA, Sivenius J, Salonen R, Kaplan GA, Salonen JT.(PubMed)
(4) Healthy eating and stroke(Stroke Foundation)
(5) Stroke Statistics by The Internet Stroke center
Monday, November 12, 2018
Garlic, The Herb and Roots Spice That Gobbles Up Arterial Plaques Before They Can Cause Atherosclerosis
A recent study suggested that patients with atherosclerosis may be benefits from adding aged garlic extract with supplement into their diet.
Atherosclerosis is a disease with plaque builds up inside the arteries, affecting the levels of oxygen in the blood as well as increasing risks of heart attacks, strokes, and peripheral vascular disease.
Atherosclerosis is a slow, progressive disease that may begin as early as childhood, caused by damage of the inner lining of the artery. However, the actual causes of the condition are debatable.
Some researchers suggested that atherosclerosis may be caused by long-term high blood pressure,
high cholesterol and triglycerides (a type of fat) in the blood. Particularly, in high levels of insulin in the blood from diabetes and in exposure to chemicals from smoking tobacco.
Patients at the early stage of atherosclerosis may not experience any symptoms. However, as the disease progress, patients may have the symptoms of chest pain if the blockage occurs in an artery of the heart (coronary artery) and leg cramps during exercise or walking if the blockage occurs in the legs.
At the advanced stage, if atherosclerosis develops in the arteries or the brain, it may cause a heart attack and stroke, respectively.
Truly, change and diet and life style not only has a strong impact in prevent early onset of atherosclerosis but also inhibits progression of the condition.
Dr.Torres N the lead scientist in the joint study of conducted by the Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, said, " In many cases, diet is a major driving force, which is much easier to change and follow than other factors. It is important to establish that the first strategy to treat atherosclerosis is to modify lifestyle habits, focusing on the beneficial properties of specific nutrients" and " epidemiological, clinical and experimental studies have demonstrated that diet plays a central role in the prevention of atherosclerosis. In particular, we include information about fiber, plant sterols and stanols, niacin, taurine, olive oil, omega 3 fatty acids, antioxidants, minerals, methyl nutrients and soy"(5).
Garlic (Allium sativum) is a species in the onion genus, belonging to family Amaryllidaceae, native to central Asia, used popularly in traditional and Chinese medicine in treating common cold and flu to the Plague, blood pressure cholesterol levels, natural antibiotic, etc.
According to the UCLA-School of Medicine, Los Angeles, the effectiveness of garlic in reduced homocysteine and progression of Atherosclerosis is the result of the changing white (wEAT) and brown (bEAT) epicardial adipose tissue(a form of visceral fat deposited around the heart) in plaque stabilization.
In a placebo-controlled, double-blind, randomized trial (conducted 2005-2007), with 65 intermediate risk patients (age 60+/-9 years) treated with a capsule containing aged garlic extract (250 mg) plus Vitamin B12 (100 microg), folic acid (300 microg), Vitamin B6 (12.5 mg) and l-arginine (100 mg) daily for a 1 year, researchers found that the application exerts a favorable improvement in oxidative biomarkers, vascular function, and reduced progression of atherosclerosis.
(AGE) retard the progression of coronary calcification in patients with coronary artery disease in vitro and vivo,
Dr. Morihara N, the lead author at the joint study said, " Antiatherosclerotic activity of AGE is at least partly due to the suppression of inflammation and lipid deposition in the vessels during the early stage of atherosclerotic development".
The experiment of a total of 157 healthy postmenopausal women (age 65 ± 6) randomized study, 500 mg isoflavonoid-rich herbal preparation, including garlic powder, reduced risk of cardiovascular disease and atherosclerosis progression through lowering high blood cholesterol.
Although garlic prevents the development of cholesterol-induced experimental atherosclerosis and possesses the direct anti-atherogenic activity, intake of garlic supplement should be taken with care to patients with ulcer.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Loose Weight
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Home page http://kylejnorton.blogspot.ca
Kyle J. Norton, Master of Nutrition
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.
Sources
(1) Aged garlic extract with supplement is associated with increase in brown adipose, decrease in white adipose tissue and predict lack of progression in coronary atherosclerosis by Ahmadi N1, Nabavi V, Hajsadeghi F, Zeb I, Flores F, Ebrahimi R, Budoff M.(PubMed)
(2) Aged garlic extract supplemented with B vitamins, folic acid and L-arginine retards the progression of subclinical atherosclerosis: a randomized clinical trial by Budoff MJ1, Ahmadi N, Gul KM, Liu ST, Flores FR, Tiano J, Takasu J, Miller E, Tsimikas S.(PubMed)
(3) Aged Garlic Extract Suppresses the Development of Atherosclerosis in Apolipoprotein E-Knockout Mice by Morihara N1, Hino A2, Yamaguchi T3, Suzuki J3.(PubMed)
(4) Anti-atherosclerotic effects of garlic preparation in freeze injury model of atherosclerosis in cholesterol-fed rabbits by Sobenin IA1, Andrianova IV2, Lakunin KY3, Karagodin VP4, Bobryshev YV5, Orekhov AN6.(PubMed)
(5) Nutrition and Atherosclerosis by Torres N1, Guevara-Cruz M1, Velázquez-Villegas LA1, Tovar AR(PubMed)
Atherosclerosis is a disease with plaque builds up inside the arteries, affecting the levels of oxygen in the blood as well as increasing risks of heart attacks, strokes, and peripheral vascular disease.
Atherosclerosis is a slow, progressive disease that may begin as early as childhood, caused by damage of the inner lining of the artery. However, the actual causes of the condition are debatable.
Some researchers suggested that atherosclerosis may be caused by long-term high blood pressure,
high cholesterol and triglycerides (a type of fat) in the blood. Particularly, in high levels of insulin in the blood from diabetes and in exposure to chemicals from smoking tobacco.
Patients at the early stage of atherosclerosis may not experience any symptoms. However, as the disease progress, patients may have the symptoms of chest pain if the blockage occurs in an artery of the heart (coronary artery) and leg cramps during exercise or walking if the blockage occurs in the legs.
At the advanced stage, if atherosclerosis develops in the arteries or the brain, it may cause a heart attack and stroke, respectively.
Truly, change and diet and life style not only has a strong impact in prevent early onset of atherosclerosis but also inhibits progression of the condition.
Dr.Torres N the lead scientist in the joint study of conducted by the Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, said, " In many cases, diet is a major driving force, which is much easier to change and follow than other factors. It is important to establish that the first strategy to treat atherosclerosis is to modify lifestyle habits, focusing on the beneficial properties of specific nutrients" and " epidemiological, clinical and experimental studies have demonstrated that diet plays a central role in the prevention of atherosclerosis. In particular, we include information about fiber, plant sterols and stanols, niacin, taurine, olive oil, omega 3 fatty acids, antioxidants, minerals, methyl nutrients and soy"(5).
Garlic (Allium sativum) is a species in the onion genus, belonging to family Amaryllidaceae, native to central Asia, used popularly in traditional and Chinese medicine in treating common cold and flu to the Plague, blood pressure cholesterol levels, natural antibiotic, etc.
According to the UCLA-School of Medicine, Los Angeles, the effectiveness of garlic in reduced homocysteine and progression of Atherosclerosis is the result of the changing white (wEAT) and brown (bEAT) epicardial adipose tissue(a form of visceral fat deposited around the heart) in plaque stabilization.
In a placebo-controlled, double-blind, randomized trial (conducted 2005-2007), with 65 intermediate risk patients (age 60+/-9 years) treated with a capsule containing aged garlic extract (250 mg) plus Vitamin B12 (100 microg), folic acid (300 microg), Vitamin B6 (12.5 mg) and l-arginine (100 mg) daily for a 1 year, researchers found that the application exerts a favorable improvement in oxidative biomarkers, vascular function, and reduced progression of atherosclerosis.
(AGE) retard the progression of coronary calcification in patients with coronary artery disease in vitro and vivo,
Dr. Morihara N, the lead author at the joint study said, " Antiatherosclerotic activity of AGE is at least partly due to the suppression of inflammation and lipid deposition in the vessels during the early stage of atherosclerotic development".
The experiment of a total of 157 healthy postmenopausal women (age 65 ± 6) randomized study, 500 mg isoflavonoid-rich herbal preparation, including garlic powder, reduced risk of cardiovascular disease and atherosclerosis progression through lowering high blood cholesterol.
Although garlic prevents the development of cholesterol-induced experimental atherosclerosis and possesses the direct anti-atherogenic activity, intake of garlic supplement should be taken with care to patients with ulcer.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Loose Weight
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Home page http://kylejnorton.blogspot.ca
Kyle J. Norton, Master of Nutrition
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.
Sources
(1) Aged garlic extract with supplement is associated with increase in brown adipose, decrease in white adipose tissue and predict lack of progression in coronary atherosclerosis by Ahmadi N1, Nabavi V, Hajsadeghi F, Zeb I, Flores F, Ebrahimi R, Budoff M.(PubMed)
(2) Aged garlic extract supplemented with B vitamins, folic acid and L-arginine retards the progression of subclinical atherosclerosis: a randomized clinical trial by Budoff MJ1, Ahmadi N, Gul KM, Liu ST, Flores FR, Tiano J, Takasu J, Miller E, Tsimikas S.(PubMed)
(3) Aged Garlic Extract Suppresses the Development of Atherosclerosis in Apolipoprotein E-Knockout Mice by Morihara N1, Hino A2, Yamaguchi T3, Suzuki J3.(PubMed)
(4) Anti-atherosclerotic effects of garlic preparation in freeze injury model of atherosclerosis in cholesterol-fed rabbits by Sobenin IA1, Andrianova IV2, Lakunin KY3, Karagodin VP4, Bobryshev YV5, Orekhov AN6.(PubMed)
(5) Nutrition and Atherosclerosis by Torres N1, Guevara-Cruz M1, Velázquez-Villegas LA1, Tovar AR(PubMed)
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