Wednesday, January 20, 2016

)The tasty Smoothie of Green Tea, Grape and Avocado for Reduced Risk and Treatment of Pelvic inflammation disease (PID)


Kyle J. Norton(Scholar, Master of Nutrients), all right reserved.
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.


The smoothie for reduced risk and treatment of pelvic inflammation disease
Yield: 2 serving (about 8 ounce each)
1 cup grape
1/4 cup avocado


1 cup green tea drink (Make from 4 grams of green tea, a slice of ginger and a cup of hot water lipped for 5 minutes, and let cool to room temperature)

1. Place all ingredients in a blender and puree about 1 minute
2. Blend on high speed about 1 minute or until the mixture is thick and the ice is well crushed. Add more green tea drink if needed
3. Serve immediately

The finding the natural ingredients for treatment of pelvic inflammation disease  is considered as a dream of many scientist to replace the long term usage adverse effect of conventional medicine.
Unfortunately, many compounds found effective in initial studying failed to confirm the potential in  large sample size and multi center.

Pelvic inflammation disease (PID) is defined as condition caused by inflammation or infection of the female uterus, fallopian tubes, and/or ovaries as a result of scars and adhesion in the pelvic which in turn may prevent the implantation of egg during natural pregnancy process. It affects over 1 million women in U.S. every month and most of them are in their teen and twenties and over 100,000 women become infertile in the US alone each year.
Recent studies reported by some well known institution, green tea, may process the anti inflammatory diseases, including inhibition of pelvic inflammation disease (PID), as pelvic inflammatory disease is
associated to increased expressions of Th1 cytokine IFN-gamma, and Th2 cytokine IL-5, related to pro inflammatory pathways(2).

Recent studies back by renowned institution suggested, Green tea(1) and carrot, tomato(4) may have a potential and therapeutic value for reduced risk and treatment of cervical cancer probably due to theirs' phytochemicals effect in ameliorated proliferation of cancer cell expression, recent studies suggested. According to The Catholic University of Korea, epigallocatechin-3-gallate attenuated the chronic inflammatory activities through educed the level of IFN-γ-induced priming signal in immune regulation via the down-regulation of pro-IL-1β and pro-capspase-1 in HEKn cell of proinflammatory cytokines(1).
Dr. and the colleagues at the Medical College of Ohio Ruppert proposed, theaflavins, amajor green constituent exhibited antioxidant, antineoplastic and antiinflammatory properties, including induction of IFNgamma mRNA of NF-kappaB for gene expression of pro - inflammatory pathway(3).Dr. Chen X, and professors Li W and Wang H.at the New York University School of Medicine, suggested that Green tea reduced endotoxin-induced release of (e.g., TNF, IL-1, and IFN-gamma) and (e.g., HMGB1) pro-inflammatory cytokines(4).

Avocado, a green-skinned, pear-shaped fruit that ripens after harvesting and native to the Caribbean, Mexico, South America and Central America, belonging to the flowering plant family Lauraceae, is a commercially valuable fruit and cultivated in tropical climates throughout the world.

Omega-3 polyunsaturated fatty acids (PUFA) found abundantly in avocado may possess the most potent immunomodulatory activities, and among the omega-3 PUFA in reduced risk and treatment of inflammatory and auto immune diseases caused by the increased level of interleukin 1 (IL-1), a proinflammatory cytokine(5).
Dr. Calder PC. said, "n-3 PUFA can down regulate the activity of the nuclear transcription factor NFB" and "suppressed production of pro-inflammatory cytokines and can decrease adhesion molecule expression"(6).
According to Dr. Gouveia TL and research, omega 3 fatty acids plays an important role in activation of the immune system in the central nervous system in response to the release of pro inflammatory cytokines such as IL-1β, IL-6, and TNF-α(7) of which related to the occurance of pelvic inflammatory disease(2).

Resveratrol is a phytochemical in the class of Stilbenoids, found abundantly in skins and seed of grape may also expressed the inhibition of cytokines involved the progression of pelvic inflammation disease (PID), according to Dr. Inoue H and Dr. Nakata R. said, "Resveratrol is as a phytoalexin, cyclooxygenase (COX) suppressor, and an activator of peroxisome proliferatoractivated receptor (PPAR) and SIRT1."(8).
According to the, resveratrol intake ameliorated, in a dose-dependent manner, pro-inflammatory cytokines IL-1β, TNF-α and IL-6 mRNA expression and promote the release of anti-inflammatory interleukin (IL)-10(9). of that related to reduced risk and treatment of inflammatory diseases.
In fact the effectiveness of resveratrol in reduced risk and treatment of chronic inflammatory diseases may be due to promotion of anti inflammatory and reduction of pro inflammatory properties(10).

The combination of Green Tea, Grape and Avocado smoothie may hold a key in further studies in production of an effective natural ingredients for prevention and treatment of  Pelvic inflammation disease (PID) without inducing adverse effects.

Women who are at increased risk of Pelvic inflammation disease (PID), due to family history,... should drink at least one cup daily. Women with Pelvic inflammation disease (PID) should drink as much as they can depending to the digestive toleration.

References
(1) Epigallocatechin-3-gallate attenuates the AIM2-induced secretion of IL-1β in human epidermal keratinocytes by Yun M1, Seo G1, Lee JY1, Chae GT1, Lee SB2.(PubMed)
(2) Significant elevation of a Th2 cytokine, interleukin-10, in pelvic inflammatory disease by Chen KS1, Wang PH, Yang SF, Lin DB, Lin YJ, Kuo DY, Lin LY, Wu MT, Lin CW, Lee S, Chou MC, Tsai HT, Hsieh YS.(PubMed)
(3) Tea pigments inhibit the production of type 1 (T(H1)) and type 2 (T(H2)) helper T cell cytokines in CD4(+) T cells by Tomita M1, Irwin KI, Xie ZJ, Santoro TJ.(PubMed)
(4) More tea for septic patients?--Green tea may reduce endotoxin-induced release of high mobility group box 1 and other pro-inflammatory cytokines by Chen X1, Li W, Wang H.(PubMed)
(5) Omega-3 fatty acids in inflammation and autoimmune diseases by Simopoulos AP1.(PubMed)
(6) Dietary modification of inflammation with lipids by Calder PC1.(PubMed)
(7) High serum levels of proinflammatory markers during epileptogenesis. Can omega-3 fatty acid administration reduce this process? by Gouveia TL1, Vieira de Sousa PV1, de Almeida SS2, Nejm MB1, Vieira de Brito JM1, Cysneiros RM3, de Brito MV4, Salu BR4, Oliva ML4, Scorza FA1, Naffah-Mazzacoratti Mda G5.(PubMed)
(8) Resveratrol Targets in Inflammation by Inoue H1, Nakata R.(PubMed)
(9) IL-10 plays a pivotal role in anti-inflammatory effects of resveratrol in activated microglia cells. by Cianciulli A1, Dragone T1, Calvello R1, Porro C2, Trotta T2, Lofrumento DD3, Panaro MA4.(PubMed)
(10) Resveratrol differentially modulates inflammatory responses of microglia and astrocytes by Lu X1, Ma L, Ruan L, Kong Y, Mou H, Zhang Z, Wang Z, Wang JM, Le Y.(PubMed)
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The Curable Smoothie of Papaya for Reduced Severity of Symptoms and Treatment of Anemia (β-thalassemia and sickle cell disease)

Kyle J. Norton(Scholar, Master of Nutrients), all right reserved.
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.


The smoothie for people with high risk of Anemia and Anemia
Yield: 2 serving (about 8 ounce each)
1 1/2 cups papaya
1 cup of rice milk

1. Place all ingredients in a blender and puree about 1 minute
2. Blend on high speed about 1 minute or until the mixture is thick and the ice is well crushed. Add more green tea drink if needed
3. Serve immediately

The finding the natural ingredients for treatment of anemia is considered as a dream of many scientist to replace the long usage adverse effect of conventional medicine to other organs in the body. Unfortunately, many compounds found effective in initial studying failed to confirm the potential in large sample size and multi center.

Most people understand that anemia is caused by iron deficiency in the bloodstream, but in reality anemia is characterized by deficiency in the hemoglobin of the red blood cells diminishing the ability of the blood to transport oxygen to our cells and to remove carbon dioxide.

Antioxidant plays an important role in the influences of the pharmacologic induction of fetal hemoglobin (HbF) for treatment of β-thalassemia and sickle cell disease through expression in the fetal liver, spleen and bone marrow(1).

Recent studies suggested that chronic consumption of the combination of papaya(2) may be beneficiary to reduce symptoms and treatment  for patients with anemia such as β-thalassemia and sickle cell disease.

Papaya is a species of Carica Papaya, belongs to the family Caricaceae and native to the tropics of the Americas, and was first cultivated in Mexico and several centuries. Vitamin C found abundantly in papaya out of all fruits, according to the Chinese Academy of Medical Science, improved the levels of hemoglobin-based oxygen carriers (HBOCs) through the indication of the oxygen binding curves and the molecular weights(2).
In patients with sickle cell hemoglobin from both parents and are associated with unusually large numbers of immature blood cells, C. papaya seed oil significantly increased HbSSM and HbSSF human sickle cell blood peroxidase activity and hemoglobin concentration significantly, through exhibited particular antisickling properties and reduced oxidative stress in sickle cell patient(3).

In patients with beta-thalassemia major and intermedia and E-beta-thalassemia due to defects and mutations in the beta-globin gene, fermented papaya preparation (FPP) improve the status of anemia through increased the content of reduced glutathione (GSH) in red blood cells (RBC), and decreased free radicals generation, membrane lipid peroxidation, and externalization of phosphatidylserine (PS) in beta-thal, major and intermedia, (in Israel) and E-beta-thal patients(4).
Dr. Olalla-Saad ST said, "... reduction of oxidative status in red blood cells of patients with β- and E-β-thalassemia (β-thal) treated with fermented papaya preparation"(5) of that reducing the severity of the symptoms of anemia(6).

In fact, on sickle cell trait (HbAS) and sickle cell disease (HbSS) blood samples, long term consumption of tropical fruit extract, Carica papaya produced significant less numbers of sickle cells, the Covenant University study suggested(7).

People who are at increased risk of anemia (β-thalassemia and sickle cell disease) due to family history, genetic mutation .....should drink at least 2 serving daily and people with chronic anemia (β-thalassemia and sickle cell disease) should drink the juices as much as they can, depending to digestive toleration.
Change of life style and diet pattern are also recommended.

All Forms of Arthritis are Curable
You Can Eliminate Osteoarthritis
By addressing the Underlying Causes through Clinical Trials and Studies

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to General health http://kylejnorton.blogspot.ca/p/general-health.html

Back to Kyle J. Norton Home page http://kylejnorton.blogspot.ca

References
(1) Induction of human fetal hemoglobin via the NRF2 antioxidant response signaling pathway by Macari ER1, Lowrey CH.(PubMed)
(2) Antioxidant effects of vitamin C on hemoglobin-based oxygen carriers derived from human cord blood by Chen G1, Duan Y1, Liu J1, Wang H1, Yang C1,2.(PubMed)
(3) Solenostemon monostachyus, Ipomoea involucrata and Carica papaya seed oil versus Glutathione, or Vernonia amygdalina: methanolic extracts of novel plants for the management of sickle cell anemia disease by Afolabi IS1, Osikoya IO, Fajimi OD, Usoro PI, Ogunleye DO, Bisi-Adeniyi T, Adeyemi AO, Adekeye BT.(PubMed)
(4) Amelioration of oxidative stress in red blood cells from patients with beta-thalassemia major and intermedia and E-beta-thalassemia following administration of a fermented papaya preparation.
Fibach E1, Tan ES, Jamuar S, Ng I, Amer J, Rachmilewitz EA.(PubMed)
(5) Fermented papaya preparation for β-thalassemia? by Olalla-Saad ST1.(PubMed)
(6) Fermented papaya preparation as redox regulator in blood cells of beta-thalassemic mice and patients by Amer J1, Goldfarb A, Rachmilewitz EA, Fibach E.(PubMed)
(7) Preliminary in vitro antisickilng properties of crude juice extracts of Persia Americana, Citrus sinensis, Carica papaya and Ciklavit® by Iweala EE1, Uhegbu FO, Ogu GN.(PubMed)
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Most Common Diseases of elder: Bronchiectasis (Respiratory Disease) – The Complications

Kyle J. Norton(Scholar and Master of Nutrients, all right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

Respiratory Disease is defined as medical conditions which affect the breathing organ and tissues including Inflammatory lung disease, Obstructive lung diseases, Restrictive lung diseases, Respiratory tract infections, trachea, bronchi, bronchioles, alveoli, the nerves and muscles breathing , etc,.

                                              Bronchiectasis

Bronchiectasis is defined as a condition chracterized by the damage of the localized, irreversible dilation of part of the bronchial tree and the walls of the large airways of the lung as a result of the destruction of the lung muscles and elastic tissues. Bronchiectasis can be present alone, but in most cases, it is a disease coexisted with patient of chronic obstructive pulmonary disease (COPD).

                                                The  Complications

 1. Arterial stiffness (an indicator of increased CV risk), increased inflammation, reduced exercise capacity and bone thinning
In the study to investigate of a total of 20 patients with noncystic fibrosis bronchiectasis and compare to 20 controls similar in age, gender and smoking exposure, found that Patients with bronchiectasis had increased arterial stiffness (an indicator of increased CV risk), increased inflammation, reduced exercise capacity and bone thinning(28).

2. T Hemoptysis
T Hemoptysis is a common complication of bronchiectasis. Patients with bronchiectasis complicated by primary hyperfibrolysis do not respond to regular treatment for hemoptysis, which may potential cause fatal consequences, according to the study by Department of Respiratory Diseases, Southern Medical University.(29).

3. Acute respiratory failure from bilateral broncholithiasis
There is a report of a case of acute airway obstruction secondary to bilateral broncholiths. Successful management was achieved with rigid bronchoscopy(30).

4. Endobronchial nocardiosis
There is a report of a case of endobronchial nocardiosis associated with the presence of a broncholith(31).

5. Pneumonia
There is a report of a 56-year-old woman visited our hospital in 2003 and right upper lobe pneumonia was detected with a calcified nodule that completely obstructed the right upper lobe bronchus on CT. After admission, she spontaneously expectorated a stone. The composition of the stone was 57% calcium phosphate and 43% calcium carbonate. Radiological findings and the composition of the stone suggested that this broncholith was calcified bronchial mucus rather than a calcified lymph node that might have perforated into the airway. Bronchiectasis of the right B3 broncus was observed on CT scan after lithoptysis. Although the bronchiectasis was unchanged 2 years later, she had no symptoms, such as fever or cough(32).
6. Etc.

All Forms of Arthritis are Curable
You Can Eliminate Osteoarthritis
By addressing the Underlying Causes through Clinical Trials and Studies

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to General health http://kylejnorton.blogspot.ca/p/general-health.html

Back to Kyle J. Norton Home page http://kylejnorton.blogspot.ca
Sources
(28) http://www.ncbi.nlm.nih.gov/pubmed/23129800
(29) http://www.ncbi.nlm.nih.gov/pubmed/23076203
(30) http://journal.publications.chestnet.org/article.aspx?articleid=1078716
(31) http://www.ncbi.nlm.nih.gov/pubmed/19350841
(32) http://www.ncbi.nlm.nih.gov/pubmed/18318256
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Tuesday, January 19, 2016

The Curable Smoothie of Green Tea, Almond and Camel Milk for Reduced Symptoms and Treatment of Autism

Kyle J. Norton(Scholar, Master of Nutrients), all right reserved.
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.


The smoothie for Prevention and Treatment of Autism
Yield: 2 serving (about 8 ounce each)
1/4 cup almond
4/5 cup of camel milk
1 cup green tea drink (Make from 4 grams(2 tea bags) of green tea, and a cup of hot water lipped for 5 minutes, and set aside for cooling to room temperature)

1. Place all ingredients in a blender and puree about 1 minute
2. Blend on high speed about 1 minute or until the mixture is thick and the ice is well crushed. Add more green tea drink if needed
3. Serve immediately

The finding the natural ingredients for treatment of autism is considered as a dream of many scientist to replace the long usage adverse effect of conventional medicine to other organs in the body. Unfortunately, many compounds found effective in initial studying failed to confirm the potential in large sample size and multi center.

the combination of Green Tea(3), Almond(4) and Camel Milk(7) may be a protential formula for reduced severity of symptoms and treatment of autism, recent studies found 

Autism is one most common form of brain development disorder in children. According to statistic one in 166 child is diagnosed with some forms of autism. Children who are diagnosed with autism tend to have weak immune system and auto immune problems. Autism is defined as medical condition in which a child has some of the following impairments(1)
a) Speech
b) Social and communication skills
c) Limited interest
d) Repetitive behaviour
According to the joint study lead by the Murdoch Childrens Research Institute, Very preterm (VP) children with autism spectrum disorder (ASD) have different brain structure in the neonatal period compared with those who do not have ASD(2).

Green tea has been a precious drink in traditional Chinese culture and used exceptional in socialization for more than 4000 thousand years. Because of their health benefits, they have been cultivated for commercial purposes all over the world.

According Dr. Banji D and colleagues, in mice with in neurobehavioral aberrations, oral administration of green tea induced neuronal protection against the impact of toxicants, and improved motor co-ordination, nociceptive response, locomotion, anxiety, exploratory activity and cognition on various postnatal days through its neuronal cytoprotective against symptoms of autism(3).

Almond consists of an outer hull and a hard shell with the seed (nut) inside is native to the Middle East. It is most widely cultivated seed in the world for it economic and health benefit.
Omega-3 fatty acids, an unsaturated fatty acids, with three double bonds at particular positions in the hydrocarbon chain, found abundantly in almond, in an open-label pilot study of 10 children aged 4-7 years old with ASD improved 8 showed about 33% on the Autism Treatment Evaluation Checklist (ATEC) of 8 children(4).
In a total of 41 children and adolescents aged 7-18 years (36 boys, 5 girls; mean age = 11.66, s.d. = 3.05) diagnosed with ASD, the use of omega-3 fatty acids supplementation showed a significant improvements on all subscales of the Social Responsiveness Scale (P < 0.01) and the Social and Attention Problems syndrome scales of the Child Behavior Checklist (P < 0.05) with Blood fatty acid levels were significantly correlated with changes in the core symptoms of ASD, according to the study lead by the University of Basel(5).
In support of the above conclusion, The joint study lead by the Massachusetts General Hospital and Harvard Medical School, suggested that abnormal lipid metabolism is implicated in autism(6). 

Camel milk, may also be another ingredient for treatment of autism, as it reduced the oxidative stress in several neurological diseases, including autismspectrum disorder (ASD), through improvment of levels of antioxidant and autistic behaviour as demonstrated on Childhood Autism Rating Scale (CARS)(7).
Dr. Al-Ayadhi LY and researchers at the King Saud University also insisted that camel milk improve behavioral characteristic in 65 (boys=60, girls=5) children with autism (aged from 2 to 12 years) after after the 2 weeks of therapy(8).
Dr. Adams CM, the researcher of Author/professional writer, Laguna Beach said," Beginning at age 9, he drank one half cup of raw camel milk a day and experienced overnight an improvement in his symptoms. His continued regular consumption of camel milk was associated with sustained symptom improvements for 6 consecutive years (2007-2013)." in a report of his son, who was diagnosed with autism spectrum disorder (ASD) at 3 years of age(9).

Taking all together, intake of the smoothie with green tea, almond and camel milk is found to reduce the severity of  symptoms and enhance treatment of Autism,  adult with autism should drink as much as possible depending to the digestive toleration.

Please note: for children with autism, the volume of green tea should be replaced by the same volume of camel milk.


References
(1) [Basics of early intervention in children with autism spectrum disorders].[Article in Spanish] by Zalaquett DF1, Schönstedt MG2, Angeli M3, Herrrera CC4, Moyano AC5.(PubMed)
(2) Neonatal brain abnormalities associated with autism spectrum disorder in children born very preterm by Ure AM1,2, Treyvaud K1,3, Thompson DK1,3, Pascoe L1, Roberts G1,2,3, Lee KJ1,3, Seal ML1,3, Northam E1,3, Cheong JL1,3,4, Hunt RW1,2,3, Inder T5, Doyle LW3,4, Anderson PJ3.(PubMed)
(3) Amelioration of behavioral aberrations and oxidative markers by green tea extract in valproate induced autism in animals by Banji D1, Banji OJ, Abbagoni S, Hayath MS, Kambam S, Chiluka VL.(PubMed)
(4) Omega 3 fatty acid treatment in autism by Meiri G1, Bichovsky Y, Belmaker RH.(PubMed)
(5) Omega-3 fatty acids in the management of autism spectrum disorders: findings from an open-label pilot study in Singapore by Ooi YP1, Weng SJ2, Jang LY3, Low L3, Seah J3, Teo S3, Ang RP4, Lim CG2, Liew A3, Fung DS5, Sung M3.(PubMed)
(6) Autistic children exhibit decreased levels of essential Fatty acids in red blood cells by Brigandi SA1, Shao H2, Qian SY3, Shen Y4, Wu BL5, Kang JX6.(PubMed)
(7) Camel Milk as a Potential Therapy as an Antioxidant in Autism Spectrum Disorder (ASD) by Al-Ayadhi LY1, Elamin NE.(PubMed)
(8) Behavioral Benefits of Camel Milk in Subjects with Autism Spectrum Disorder by Al-Ayadhi LY1, Halepoto DM2, Al-Dress AM1, Mitwali Y2, Zainah R2.(PubMed)
(9) Patient report: autism spectrum disorder treated with camel milk by Adams CM1.(PubMed)
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Most Common Diseases of elder: Bronchiectasis (Respiratory Disease) – The Risk Factors

Kyle J. Norton(Scholar and Master of Nutrients, all right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

Respiratory Disease is defined as medical conditions which affect the breathing organ and tissues including Inflammatory lung disease, Obstructive lung diseases, Restrictive lung diseases, Respiratory tract infections, trachea, bronchi, bronchioles, alveoli, the nerves and muscles breathing , etc,.

                                              Bronchiectasis

Bronchiectasis is defined as a condition chracterized by the damage of the localized, irreversible dilation of part of the bronchial tree and the walls of the large airways of the lung as a result of the destruction of the lung muscles and elastic tissues. Bronchiectasis can be present alone, but in most cases, it is a disease coexisted with patient of chronic obstructive pulmonary disease (COPD).


                                                   The  Risk factors


1. Tuberculosis, tobacco smoking and exposure to indoor air pollution
Tuberculosis, tobacco smoking and exposure to indoor air pollution are associated to increased risk of bronchiectasis. In the study to describe the clinical spectrum of the patients presenting with bronchiectasis at the referral clinic for the respiratory diseases in eastern Nepal, conducted by Department of Internal Medicine, B.P. Koirala Institute of Health Sciences, indicated that in Nepal bronchiectasis remains one of the important chronic respiratory diseases, post tubercular variety being the commonest type. Tuberculosis, tobacco smoking and exposure to indoor air pollution contributes towards higher morbidity of this diseases(14). Other suggested that increasedsmokers, urbanization and air pollution are associated to the prevalence of the Morbidity and mortality of respiratory diseases(14a).

2. Gender
If you are women, you are at increased risk of Bronchiectasis. According to the study by
University of California-Davis School of Medicine, bronchiectasis in women may act more virulently. Identified gender and sex differences range from increased exposure risks to altered inflammatory responses. There is sufficient evidence to suggest that chronic airway infection, most notably non-CF bronchiectasis, is a more common and more virulent disease in women(15).

3. Systemic inflammation and accelerated aging
Systemic inflammation, the consequences of systemic inflammation, the possibility of accelerated aging, and of how these concepts could relate to shared genetic risk factors for both comorbidity and pulmonary aspects of COPD, including small airways diseases, chronic bronchitis and bronchiectasis, as well as pulmonary emphysema(16).

4. Family history and other diseases
There is a report of a 68 year old woman with a lifelong history of chronic bronchitis diagnosed as having cystic fibrosis. The diagnosis was based on a suggestive family history, steatorrhoea, bronchiectasis with respiratory insufficiency, and very high sweat sodium content. The patient was found to be heterozygous for the delta F 508 gene defect(17).

5. Delay diagnosis
In the study to provide advice regarding when to suspect bronchiectasis, how to proceed with confirming or refuting a diagnosis, and the principles of management to minimise disease progression and manage the acute exacerbations, symptoms and associated disability and impaired quality of life, found that delay in the diagnosis, investigation and management of bronchiectasis in both children and adults is common, and this delay has been shown to be associated with more rapid progression of disease(18).
6. Etc.

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Monday, January 18, 2016

The Curable Smoothie of Yogurt and Honey for reduced risk and treatment of Allergy

Kyle J. Norton(Scholar, Master of Nutrients), all right reserved.
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.


The smoothie for people with high risk of Anemia and Anemia
Yield: 2 serving (about 8 ounce each)
1 1/4 cup yogurt
1/4 cup honey
1 cup of rice milk

1. Place all ingredients in a blender and puree about 1 minute
2. Blend on high speed about 1 minute or until the mixture is thick and the ice is well crushed. Add more green tea drink if needed
3. Serve immediately

The finding the natural ingredients for treatment of allergy is considered as a dream of many scientist to replace the long usage adverse effect of conventional medicine to other organs in the body. Unfortunately, many compounds found effective in initial studying failed to confirm the potential in large sample size and multi center.

Allergy is the over reaction of immune system to harmless substances after entering our body affecting 1 in every 3 people and is defined as the type I reactions or Immediate Hypersensitivity as a result of over production of Immunoglobulin E (IgE), a class of allergic antibody by the immune system against harmless substances of that increasingly lead to mediated release of histamine and other mediators from mast cells and basophils, resulting in allergic reaction, including mucus secretion, sneezing, itching, etc.

Recent studies suggested that the combination of yogurt(1) and honey(4) may hold an important information as a therapeutic value in reduced risk and treatment of allergy.

Yogurt, made from milk products through bacterial fermentation is considered as one of most healthy foods in balancing the bacteria in the digestive system. Dr. Brown-Riggs C said," yogurt is often a more easily digestible alternative to milk, and thus more palatable to people who experience symptoms of lactose intolerance. This was a key factor cited in the final rule to include yogurt in the Special Supplemental Nutrition Program for Women, Infants, and Children"(1).
According to the joint study lead by the Food Science Research Laboratories, R&D Division, yogurt fermented with different strains of lactobacilli and their metabolite exhibited increasing immunostimulatory exopolysaccharide (EPS) effects by keeping immune functions stable(2) against allergy.
In a randomized, double-blind, placebo-controlled trial, 44 JCPsis subjects, intake of yogurt or powder supplemented with the Bifidobacterium longum BB536 probiotic strain alleviated allergic symptoms during the pollen seasons of 2004 and 2005, through maintaining the normal function of microorganisms inhabiting the human body in health and disease(3).

The rich golden liquid is the miraculous product made by bees using nectar from flowers and considered as one of healthy sweet food for replacing the use of white sugar and artificial sweetener by many people with benefits of treating cough, fever, and inflammation in folk medicine.

In air inflammatory diseases, including asthma, aerosolised honey induced structural changes of the epithelium, mucosa, and submucosal regions of the airway that caused by the induction with ovalbumin(OVA)(4).
Manuka honey (MH) produced from the nectar of the mānuka tree at a concentration between 0.9 and 1.8 mg/mL may be safe to mucosa and efficacious treatment option for recalcitrant chronic rhinosinusitis (CRS), according to the University of Adelaide(5).

Local honey, in fact hold a important cue for reduced risk of allergy in city and local population, due to its effects in attenuated allergic reaction, such as sneezing and runny noses, according to the article of Seasonal Allergies? A Spoonful of Honey, posted in New York time on April 11-2010, the author to the editor said,"there is a simpler way for allergy sufferers to find relief: local honey. This remedy (predating Claritin and its ilk) has long been recognized around the world"(6).

Taking all together, people with high risk of allergy due to family history, weaken immune system should drink at least a serving daily to prevent the develop of seasonal allergy.
Taking foods, such as garlic, ginger, turmeric, etc.... in enhancing immunity are recommended

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References
(1) Nutrition and Health Disparities: The Role of Dairy in Improving Minority Health Outcomes by Brown-Riggs C1.(PubMed)
(2) Enhanced natural killer cell activation by exopolysaccharides derived from yogurt fermented with Lactobacillus delbrueckii ssp. bulgaricus OLL1073R-1 by Makino S1, Sato A2, Goto A2, Nakamura M2, Ogawa M2, Chiba Y2, Hemmi J2, Kano H2, Takeda K3, Okumura K4, Asami Y2.(PubMed)
(3) Influence of Bifidobacterium longum BB536 intake on faecal microbiota in individuals with Japanese cedar pollinosis during the pollen season by Odamaki T1, Xiao JZ, Iwabuchi N, Sakamoto M, Takahashi N, Kondo S, Miyaji K, Iwatsuki K, Togashi H, Enomoto T, Benno Y.(PubMed)
(4) Inhalation of honey reduces airway inflammation and histopathological changes in a rabbit model of ovalbumin-induced chronic asthma by Kamaruzaman NA, Sulaiman SA, Kaur G, Yahaya B1.(PubMed)
(5) Methylglyoxal-augmented manuka honey as a topical anti-Staphylococcus aureus biofilm agent: safety and efficacy in an in vivo model by Paramasivan S1, Drilling AJ, Jardeleza C, Jervis-Bardy J, Vreugde S, Wormald PJ.(PubMed)
(6)  Seasonal Allergies? A Spoonful of Honey(NYtimes)

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Most Common Diseases of elder: Bronchiectasis (Respiratory Disease) – The Causes

Kyle J. Norton(Scholar and Master of Nutrients, all right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

Respiratory Disease is defined as medical conditions which affect the breathing organ and tissues including Inflammatory lung disease, Obstructive lung diseases, Restrictive lung diseases, Respiratory tract infections, trachea, bronchi, bronchioles, alveoli, the nerves and muscles breathing , etc,.

                                              Bronchiectasis

Bronchiectasis is defined as a condition chracterized by the damage of the localized, irreversible dilation of part of the bronchial tree and the walls of the large airways of the lung as a result of the destruction of the lung muscles and elastic tissues. Bronchiectasis can be present alone, but in most cases, it is a disease coexisted with patient of chronic obstructive pulmonary disease (COPD).

                                         The Causes

1. Congenital bronchiectasis
In cystic fibrosis, mutations of the CFTR gene lead to diffuse bronchiectasis (DB).and the disease is associated with other diseases including rheumatoid arthritis (RA). In the study to to determine whether the frequency of CFTR mutations was higher in patients with RA-associated DB and to determine whether a causal relationship could be established between the variant and the disease by evaluating its cosegregation with DB within families, found that the frequency of CFTR mutations was higher in family members with RA-DB or DB only than in unaffected relatives (p<0.005 for each comparison) and in unrelated healthy controls (p<0.001 for each comparison) but not in family members with RA only. CFTR mutations were more frequent in family members with RA-DB than in those with RA only (OR 5.30, 95% CI 2.48 to 11.33; p<5×10(-5)). They cosegregated with RA-DB in the families (sib-TDT=10.82, p=0.005)(8).

2. Gene
Alpha-1-antitrypsin (A1AT) is the main inhibitor of neutrophil elastase, and severe alpha-1-antitrypsin deficiency (A1ATD) is a genetic risk factor for early-onset emphysema. In the study to investigate the adults with chronic obstructive pulmonary disease (COPD) (n=348), asthma (n=71), and bronchiectasis (n=35)with the control was 1435 healthy blood donors, showed that The high prevalence of A1ATD phenotypes/allele in our population has confirmed the necessity of screening for A1ATD in patients with COPD(9). Other study indicated that clinically significant bronchiectasis (radiologic bronchiectasis in 4 or more bronchopulmonary segments together with symptoms of regular sputum production) occurred in 20 subjects (27%). AAT-deficient index cases had higher airway disease scores (P < 0.05), more severe emphysema (P < 0.001), and greater impairment of physiology (P < 0.001) and health status (P < 0.05) than nonindex cases. Airway disease scores correlated with health status, and bronchial wall thickening correlated with FEV(1)(10).

3. Smoke
The long-term course of a patient with bronchiectasis and bronchiolitis obliterans, both of which developed as late complications of a smoke inhalation injury. Sequential chest X-rays obtained during the observation period showed gradual progression of bronchiectasis from the saccular to the cystic type, according to the study by Department of Medicine, School of Medicine, Keio University(11).

4. Others
In the study to to determine causative factors in 150 adults with bronchiectasis (56 male, 94 female) identified using high-resolution computerized tomography, found that immotile cilia syndrome (primary ciliary dyskinesia) and genetic anomalies that are associated with a humoral or cellular immunodeficiency are common causes of bronchiectasis., includingimmune defects (12 cases), cystic fibrosis (4), Young’s syndrome (5), ciliary dysfunction (3), aspiration (6), panbronchiolitis (1), congenital defect (1), ABPA (11), rheumatoid arthritis (4), and early childhood pneumonia, pertussis, or measles (44)(12). In other study, researchers at the indicated that Broncholithiasis is a rare condition in which calcified material erodes into the tracheobronchial tree. Most are caused from afungal, nocardial, mycobacterial, or silicosis-related granulomatous lymphadenitis. Over time, the peribronchial lymph nodes become calcified; thereafter, with the normal repetitive motions of respiration, circulation, and deglutition, the calcifications erode into the lumen of the airway(13).
5. Etc.
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