Medical Advisor Journals

Thursday, March 24, 2016

The Smoothie of Cooked Tomato, broccoli and Orange Juice for Prevention and Treatment of Hyperalbuminemia

Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.

Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post

Nominated for shorty award over last 4 years

Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

The smoothie for prevention and treatment of
Hyperalbuminuria

Yield: 2 servings (about 8 ounces each)

1 1/4 cups tomato

1/2 cup broccoli
1 cup organic orange juice

1. Place all ingredients in a blender and puree about 1 minute

2. Blend on high speed about 1 minute or until the mixture is thick and the ice is well crushed.

3. Serve immediately

The finding of a natural source for treatment of Albuminuria has been running into many obstacles, many ingredients showed initially with promising result in animal studies have not produced same potentials in large sample size and mutli centers human trials.

Recent studies back by well known institutions proposed, Cooked Tomato, broccoli and Orange Juice may be the next generation of natural ingredients for prevention and treatment of Albuminuria due to kidney decline

Albuminuria is a medical condition with too much protein in the urine, found

typically inpatients with kidney diseases. According to the Brigham and Women's Hwayospital, higher derivative vitamin A, beta-carotene, intake may reduce risk for Glomerular Filtration Rate (GFR) decline(1).

Lycopene, a chemically a carotene, also exhibited anti nephrotoxicity through anti proinflammatory pathways(3),

Coenzyme Q10, antioxidant found abundantly in broccoli may prevent or minimize cyclosporine nephrotoxicity through its antioxidant effect(4).

Dr. Ishikawa A and Dr. Homma Y. professors a the the University of Tokyo said, "Ubiquinol, the reduced form of coenzyme Q10 ......an antioxidants, may have potential for preventing CyA nephrotoxicity"(5).

In type 2 diabetes model, intake of supplement of coenzyme Q10 exhibited anti renal mitochondrial dysfunction caused by diabetic induced nephropathy(6).

Free radical scavengers vitamin C (Orange) intake, increased plasma and renal cortical vitamin C or E content in prevention of renal injury(7) and development of diabetic nephropathy(9).

According to the Yonsei University Wonju College of Medicine, vitamin C exhibited anti oxidative stress in ameliorated albuminuria and renal sclerosis in experimental diabetic rats(8).

The effectiveness of Cooked Tomato, broccoli and Orange Juice may serve as cornerstones of pharmaceutical target for further studies in production of a potential medication for reduced risk, complications and treatment of Albuminuria with little or no adverse effects.

People who are at high risk of Albuminuria due to aging, weaken renal function... should drink at least one serving daily and women with Albuminuria should drink no more than 4 servings daily, depending to digestive toleration.
Life style and diet pattern change are necessary as overweight and obesity are well-established risk factors for cardiovascular disease and decline in kidney function(2)

All Forms of Arthritis are Curable

You Can Eliminate Osteoarthritis

By addressing the Underlying Causes through Clinical Trials and Studies

Ovarian Cysts And PCOS Elimination

Holistic System In Existence That Will Show You How To

Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Super foods Library, Eat Yourself Healthy With The Best of the Best Nature Has to Offer

References
(1) Associations of diet with albuminuria and kidney function decline. by Lin J1, Hu FB, Curhan GC.(PubMed)
(2) Association between body mass index and CKD in apparently healthy men by Gelber RP1, Kurth T, Kausz AT, Manson JE, Buring JE, Levey AS, Gaziano JM.(PubMed)
(3) Nrf2/HO-1 signaling pathway may be the prime target for chemoprevention of cisplatin-induced nephrotoxicity by lycopene. Sahin K1, Tuzcu M, Sahin N, Ali S, Kucuk O.(PubMed)
(4) Effect of reduced form of coenzyme Q10 on cyclosporine nephrotoxicity by Sato T1, Ishikawa A, Homma Y.(PubMed)
(5) Beneficial effect of ubiquinol, the reduced form of coenzyme Q10, on cyclosporine nephrotoxicity by Ishikawa A1, Homma Y.(PubMed)
(6) Ubiquinone (coenzyme Q10) prevents renal mitochondrial dysfunction in an experimental model of type 2 diabetes by Sourris KC1, Harcourt BE, Tang PH, Morley AL, Huynh K, Penfold SA, Coughlan MT, Cooper ME, Nguyen TV, Ritchie RH, Forbes JM.(PubMed)
(7) Effects of supplementation with vitamin C or E on albuminuria, glomerular TGF-beta, and glomerular size in diabetes by Craven PA1, DeRubertis FR, Kagan VE, Melhem M, Studer RK.(PubMed)
(8) Blockade of oxidative stress by vitamin C ameliorates albuminuria and renal sclerosis in experimental diabetic rats by Lee EY1, Lee MY, Hong SW, Chung CH, Hong SY.(PubMed)
(9) Effect of vitamin E and vitamin C supplementation on antioxidative state and renal glomerular basement membrane thickness in diabetic kidney by Kedziora-Kornatowska K1, Szram S, Kornatowski T, Szadujkis-Szadurski L, Kedziora J, Bartosz G.(PubMed)

The Smoothie of Banana, Avocado and Herbal Ginger Tea for Prevention and Treatment of Hyperemesis gravidarum in Pregnancy

Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post

Nominated for shorty award over last 4 years

Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

The smoothie for prevention and treatment of Hyperemesis gravidarum(Liver disease)

Yield: 2 servings (about 8 ounces each)

1 cup banana

1/2 cup avocado

1 cup herbal ginger tea

1. Place all ingredients in a blender and puree about 1 minute

2. Blend on high speed about 1 minute or until the mixture is thick and the ice is well crushed.

3. Serve immediately

The finding of a natural source for treatment of intrahepatic cholestasis of pregnancy has been running into many obstacles, many ingredients showed initially with promising result in animal studies have not produced same potentials in large sample size and mutli centers human trials.

Hyperemesis gravidarum of pregnancy is a medical condition with severe nausea, vomiting, weight loss, and electrolyte disturbance during pregnancy. The prevalence of hyperemesis gravidarum of

pregnancy, may be associated to the presence of serum levels of neopterin, as a marker for immune system activation, inflammatory markers and oxidative stress(1)(2), particular Vitamin E, E equivalent, vitamin C, carotene and vitamin A levels(3).

Recent studies back by well known institutions proposed, Banana(7), Avocado(7) and Herbal Ginger Tea(4) may be the next generation of natural ingredients for prevention and treatment of hyperemesis gravidarum.

Ginger (Zingiber officinale) or ginger root is the genus Zingiber, belongings to the family Zingiberaceae, native to Tamil used in traditional and Chinese medicine to treat dyspepsia, gastroparesis, constipation, edema, difficult urination, colic, etc. According to the University of Copenhagen, powdered root of ginger in daily doses of 1 g during 4 day, scored an significantly geater relief of the symptoms hyperemesis gravidarum in comparison to placebo(4).

Dr. Sonkusare S. professor at the Melaka Manipal Medical College, said, "The management of the (hyperemesis gravidarum)condition involves symptomatic treatment along with antiemetic, pyridoxine and thiamine. Important role of alternative therapies like ginger and P6 acupoint stimulation in the treatment of hyperemesis has been identified"(5).

Truly, the search of Medline, Embase, The Cochrane Library, and other important databases up to September 2013 (Clinical Evidence reviews are updated periodically; please check our website for the most up-to-date version of this review) by Festin M, professor at the Philippine General Hospital, suggested, alternative medicine of ginger root may also be effective for reduced risk and treatment of hyperemesis gravidarum when used combination with acupressure; acupuncture; corticosteroids; metoclopramide; ondansetron; prochlorperazine; promethazine; and pyridoxine (vitamin B6)(6).

Pyridoxine, also known as vitamin B6 found abundantly in bananas, and avocados is also found to associate to reduce risk and treatment of Hyperemesis gravidarum(7).

According to the case of Naval Medical Center, in a double-blind, randomized, controlled trial in which women with nausea and vomiting of pregnancy, showed that the combination of pyridoxine and doxylamine relieved symptoms of nausea and emesis in pregnancy but lesser than those of ondansetron(8).

The effectiveness of Banana, Avocado and Herbal Ginger Tea may serve as cornerstones of pharmaceutical target for further studies in production of a potential medication for prevention and treatment of hyperemesis gravidarum with little or no adverse effects.

Women who are at high risk of hyperemesis gravidarumdue to family history, previous pregnancy..... should drink at least one serving daily and women with hyperemesis gravidarumshould drink the smoothie as much as they can, depending to digestive toleration.
Life style and dietary patter change are recommended.

All Forms of Arthritis are Curable

You Can Eliminate Osteoarthritis

By addressing the Underlying Causes through Clinical Trials and Studies

Ovarian Cysts And PCOS Elimination

Holistic System In Existence That Will Show You How To

Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Super foods Library, Eat Yourself Healthy With The Best of the Best Nature Has to Offer

References
(1) Serum levels of neopterin, inflammatory markers and oxidative stress indicators in hyperemesis gravidarum by Tunc SY1, Agacayak E1, Budak S2, Tunc N3, Icen MS1, Findik FM1, Ekinci A4, Gul T1.(PubMed)
(2) The oxidative stress index increases among patients with hyperemesis gravidarum but not in normal pregnancies by Yilmaz S, Ozgu-Erdinc AS, Demirtas C, Ozturk G, Erkaya S, Uygur D.(PubMed)
(3) Dietary antioxidant levels in hyperemesis gravidarum: a case control study by Celik F1, Guzel AI, Kuyumcuoglu U, Celik Y.(PubMed)
(4) Ginger treatment of hyperemesis gravidarum by Fischer-Rasmussen W1, Kjaer SK, Dahl C, Asping U.(PubMed)
(5) Hyperemesis gravidarum: a review. by Sonkusare S1.(PubMed)
(6) Nausea and vomiting in early pregnancy by Festin M1.(PubMed)
(7) [Treatment of hyperemesis gravidarum with combined inositol and pyridoxine].[Article in Italian] by BALESTRI F.(PubMed)
(8) Ondansetron compared with doxylamine and pyridoxine for treatment of nausea in pregnancy: a randomized controlled trial by Oliveira LG1, Capp SM, You WB, Riffenburgh RH, Carstairs SD.(PubMed)

Most Common Diseases of elder: Respiratory Pleural disease: Pleural effusion Treatment caused by Liver disease (cirrhosis)

Kyle J. Norton(Scholar and Master of Nutrients, all right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

Respiratory Disease

Respiratory Disease is defined as medical conditions, affecting the breathing organ and tissues including Inflammatory lung disease, Obstructive lung diseases, Restrictive lung diseases, Respiratory tract infections, trachea, bronchi, bronchioles, alveoli, the nerves and muscles breathing , etc,.

Pleural disease: Pleural effusion

The pleura is a thin tissue covered by a layer of cells (mesothelial cells) that surrounds the lungs and lines the inside of the chest wall.
Pleural effusion is a condition of collection of fluid within the pleural cavity as a result of heart failure, bleeding (hemothorax), infections, excessive or decreased fluid volume, etc.

TheTreatment

Treatments in conventional medicine perspective
Pleural effusion caused by Liver disease (cirrhosis)
Treatments of cirrhosis depend not only on the underlined causes but also the stages of the diseases
A.1. Alcohol causes of cirrhosis
If the the disease is caused by excessive alcohol drinking, patients will be asked to stop drinking. with help from the professional teams and certain medication. The long-term management of alcoholic liver disease stresses the following(82).
(1) Abstinence of alcohol (Grade 1A), with referral to an alcoholic rehabilitation program;
(2) Adequate nutritional support (Grade 1B), emphasizing multiple feedings and a referral to a nutritionist; (3) Routine screening in alcoholic cirrhosis to prevent complications;
(4) Timely referral to a liver transplant program for those with decompensated cirrhosis;
(5) Avoid pharmacologic therapies, as these medications have shown no benefit.
But according to the study by the Catholic University of Rome, in the intervention to achieve alcohol abstinence represents the most effective treatment for alcohol-dependent patients with liver cirrhosis by investigating the effectiveness and safety of Baclofen, is a GABA(B) receptor agonist in achieving and maintaining alcohol abstinence in patients with liver cirrhosis, showed that baclofen is effective at promoting alcohol abstinence in alcohol-dependent patients with liver cirrhosis. The drug is well tolerated and could have an important role in treatment of these individuals(83).
A.2. Obesity and Fatty liver
The prevalence of overweight and obesity are increasing in World wide, especially in the Emerging world, as a result of recently economic prosperity.
Obesity is defined as a medical condition of excess body fat accumulated overtime. Overweight is a condition of excess body weight relatively to the height. According to the Body Mass Index(BMI), a BMI between 25 to 29.9 is considered over weight, while a BMI of over 30 is an indication of obesity. In US, 68% of population are either overweight or obese. According to the study by Department of Pediatrics, Nanjing Maternity and Child Health Care Hospital, for age-specific subgroup analyses, both overweight and obesity increased more rapidly in the toddler stage than in other developmental stages. Toddlers and urban boys were at particularly high risk; the prevalence in these groups increased more rapidly than in their counterparts(84).
The Obesity Society and the American Society of Hypertension agreed to jointly sponsor a position paper on obesity-related hypertension to be published jointly in the journals of each society(2). Other researchers suggested that in light of the worldwide epidemic of obesity, and in recognition of hypertension as a major factor in the cardiovascular morbidity and mortality associated with obesity(85).
Recent study showed that evidence has emerged for an association between genetic variability at the APOA5 locus and increased risk of obesity and metabolic syndrome(86).
Fatty liver disease is defined as a condition of accumulation of fat in the liver, including people who drink little or no alcohol (Non alcohol fatty disease) or who are excessive alcohol drinking (Alcohol fatty liver disease). The disease can even occur after a short period of heavy drinking (acute alcoholic liver disease). More than 15 million people in the U.S. either abuse or overuse alcohol with fatty liver diseases with fat makes up 5-10 percent of liver weight.
Non-alcoholic fatty liver disease (NAFLD) encompasses a wide spectrum of clinical conditions, actually representing an emerging disease of great clinical interest(87)
There is no standard treatment in conventional medicine. If you are obese, you are advised to lose weight. If excessive drinking alcohol is the cause, you are advised to stop drinking.
Some researchers suggested that Vitamin E plus C combination treatment is a safe, inexpensive and effective treatment option in patients with fatty liver disease, with results comparable to those obtained with ursodeoxycholic acid(88). But some researchers suggested that Neither vitamin E nor metformin was superior to placebo in attaining the primary outcome of sustained reduction in ALT level in patients with pediatric NAFLD(89).
In traditional Chinese medicine, fatty liver is associated closely to obesity, as a result of over intake of “bad” fat and excessive alcohol drinking. Even though fatty liver is a result of too much fat, but trying to eliminate all fats from the diet won’t help to prevent or relieve the disease as malnutrition can also trigger fatty liver as fat and protein stored elsewhere in the body move to the liver for storage and conversion to energy as needed. That’s why some women who eat almost nothing but vegetables can also develop fatty liver(90).
Many traditional Chinese medicine practitioners believe, no way that one can lose weight if fatty liver diseases are not cured. Syndromes of fatty liver could be typed into 4 TCM types of the asthenia Pi-Shen with Gan-stagnation type, the asthenia Pi-Shen type, the asthenia Pi with phlegm-heat type and the unclassified type. Among them the asthenia Pi-Shen with Gan-stagnation type was the commonest one, which accounted to 62.32%(91).
Dr. Liu T, and the research team at the Shanghai University of Traditional Chinese Medicine, in the study to explore the pathogenesis of nonalcoholic fatty liver (NAFL) in traditional Chinese medicine (TCM) by comparing the therapeutic efficacy of methods for fortifying the spleen and replenishing qi, warming yang and fortifying the spleen and warming yang to move water, showed that body weight, liver and epididymal fat indexes and liver TAG level of rats all significantly increased in the model group as compared with the normal group (P<0.05). Hepatic fatty infiltration, TAG concentration and the levels of serum TAG and ALT were significantly decreased in the LGZG and SZ groups when compared to those in the model group (P<0.05). Method of warming yang or moving water can promote the lipid metabolism. It may be an effective strategy in preventing and treating NAFL by treating with warming yang and moving water together(92)
Other studies showed that Zhi Zi has a very strong inhibitory action on lipidosis and inflammatory injury in the rat model of NAFLD. This mechanism may possibly be related to the inhibition of the free fatty acid metabolism pathway(93)).
In the study to investigate the effect of Cigu Xiaozhi pills on expression of tumor necrosis factor alpha (TNF-alpha) in rat with nonalcoholic steatoheptatitis (NASH), found that Cigu Xiaozhi pills can effectively treat experimental nonalcoholic steatohepatitis in rats, and its mechanism may be associated with ameliorating hepatocellular steatosis, removing the free radicals and enhancing the capability of anti-oxidation and anti-inflammatory(94).
Most people with fatty liver disease are experience no symptoms at all, but Fatty liver disease is associated with high blood pressure, heart disease and diabetes can, in time, cause life threatening cirrhosis of the liver. According to the article By Donald Norfolk, "Today, as a direct effect of the obesity plague, it's reckoned that one in five British adults is now suffering from fatty liver disease, unconnected with virus infections or heavy drinking. This malady, known medically as steatosis, is believed to affect 90 per cent of morbidly obese patients, in whom it may remain totally symptomless for many years"(95).

All Forms of Arthritis are Curable
You Can Eliminate Osteoarthritis
By addressing the Underlying Causes through Clinical Trials and Studies

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Super foods Library, Eat Yourself Healthy With The Best of the Best Nature Has to Offer

The Best Smoothie of Carrot and Sweet Potato and Low Fat Cow Milk for Prevention of Giving Birth to Low birth-weight babies

Kyle J. Norton(Scholar, master of Nutrients), all right reserved.
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

The smoothie for reduced risk and treatment of Low birth-weight babies
Yield: 2 serving (about 8 ounce each)
1 cup sweet potato
1/2 cup carrot
1 cup of low fat cow milk

1. Place all ingredients in a blender and puree about 1 minute
2. Blend on high speed about 1 minute or until the mixture is thick and the ice is well crushed.
3. Serve immediately

The finding of a natural source for reduced risk and treatment of low birth-weight babies has encountered many obstacles, many ingredients showed initially the promising result in animal studies have not produced same potentials in large sample size and mutli centers human trials.

Low birth weight is a condition of a baby who was born below the weight of gestational age due to several reasons, including, the baby was born too soon, were small for gestational age, the poor health of the mother, nutritional deficiency, certain diseases, etc. According to the statistic of the
World health organization, globally, more than 20 million infants were born with low birth weight.

Prevalence of vitamin A E, and D deficiencies is found to associated to pre-eclampsia and lower birth-weight babies in a total of 607 VLBW and 300 term neonates(1).
Vitamin A, a fat soluble vitamin and found abundantly in carrot, is a bi-polar molecule formed by bonds between carbon and hydrogen.

Dr. Murguía-Peniche T, professor at the National Center for Child and Adolescent Health (CeASIA), said, Preterm and low birth weight infants have low levels of these nutrients and are at risk for developing detrimental health consequences associated with vitamin A and vitamin D deficiencies"(2).

The Haukeland University Hospital study suggested, In HIV-infected women, vitamin A supplementation enhanced birth weight and growth in infants. Overdosing should be avoided(3).

Vitamin E, found abundantly in sweet potato, best known for its powerful antioxidant property is a fat soluble vitamin and can be stored in our body. Pregnant women with vitamin E is connected to ivinggbirth of very low birth-weight babies(1),Dr, Shah RS and researchers at the M.S. University,said, "maternal vitamin E deficiency is one of the features associated with prematurity and intra-uterine growth retardation"(4).

Vitamin D, found in very few food but added to milk in 103-105 (IU) per cup is associated to reduced risk of giving birth of low birth-weight babies(1).

According to the Iran University of Medical Sciences, maternal Vitamin D deficiency may increase the risk of low birth weight neonate, improving maternal vitamin D level could be beneficial on pregnancy outcome(5). In support of the above, St George Hospital, Gray Street, suggested, maternal vitamin D deficiency increased the risk of neonatal vitamin D deficiency and lower birth weight and is common among pregnant women; immigrant, veiled and dark skinned women(6).

The smoothie of Carrot and Sweet Potato and Low Fat Cow Milk may hold a key for further studies in production of effective natural ingredients for prevention of giving birth to low birth-weight babies without inducing adverse effects.
Women who are pregnant with vitamin A, E and D deficiency or due to family history, ... should drink at least one cup daily, depending to the digestive toleration.

All Forms of Arthritis are Curable

You Can Eliminate Osteoarthritis

By addressing the Underlying Causes through Clinical Trials and Studies

Ovarian Cysts And PCOS Elimination

Holistic System In Existence That Will Show You How To

Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to General health http://kylejnorton.blogspot.ca/p/general-health.html

Back to Kyle J. Norton Home page http://kylejnorton.blogspot.ca

References
(1) VitaminA, E, and D deficiencies in tunisian very low birth weight neonates: prevalence and risk factors by Fares S1, Sethom MM1, Khouaja-Mokrani C2, Jabnoun S2, Feki M3, Kaabachi N1.(PubMed)
(2) Vitamin D, vitamin A, maternal-perinatal considerations: old concepts, new insights, new questions by Murguía-Peniche T1.(PubMed)
(3) Influence of mineral and vitamin supplements on pregnancy outcome by Hovdenak N1, Haram K.(PubMed))
(4) Vitamin E status of the newborn in relation to gestational age, birth weight and maternal vitamin E status. by Shah RS1, Rajalakshmi R, Bhatt RV, Hazra MN, Patel BC, Swamy NB, Patel TV.(PubMed)) Vitamin A status of the newborn in relation to gestational age, body weight, and maternal nutritional status.
Shah RS, Rajalakshmi R.(5) The Relationship between Maternal Vitamin D Deficiency and Low Birth Weight Neonates by Khalessi N1, Kalani M2, Araghi M1, Farahani Z3.(PubMed)

The Smoothie of Green tea, Orange and Grape for Prevention and Treatment of Renal Amyloidosis

Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post

Nominated for shorty award over last 4 years

Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

The smoothie for prevention and treatment of Renal Amyloidosis

Yield: 2 servings (about 8 ounces each)

1/2 cup orange
1 cup grape
1 cup green tea drink (Make from 4 grams of green tea, a slice of ginger and a cup of hot water lipped for 5 minutes, and let cool to room temperature)

1. Place all ingredients in a blender and puree about 1 minute

2. Blend on high speed about 1 minute or until the mixture is thick and the ice is well crushed.

3. Serve immediately

The finding of a natural source for treatment of Renal Amyloidosis has been running into many obstacles, many ingredients showed initially with promising result in animal studies have not produced same potentials in large sample size and mutli centers human trials.

Recent studies back by well known institutions proposed, Green tea, Orange and Grape may be the next generation of natural ingredients for prevention and treatment of Reno Amyloidosis.

Renal Amyloidosis is a condition of kidney damage caused by deposited of amyloid, affecting kidney function in filtering wastes and breaking down proteins. According to the joint study led by the Tokushima University Graduate School, (-)-epigallocatechin-3-gallate (EGCG), a tea-derived flavanol, expressed anti Reno Amyloidosis effects by inhibited fibril formation and disaggregated fibrils preformed(1).

Green tea has been a precious drink in traditional Chinese culture and used exceptional in socialization for more than 4000 thousand years. Because of their health benefits, they have been cultivated for commercial purposes all over the world. An observational study, suggested, green tea consumption is associated to amyloid fibril reduction, due to its (-)-epigallocatechin-3-gallate (EGCG) in significant decrease of left ventricular (LV) myocardial mass through stabilization of wild-type transthyretin amyloid cardiomyopathy (wtATTR-CM)(2).

Furthermore, the phytochemical isolated from greem tea also inhibited the progression of Reno Amyloidosis by modulating the rate of formation and structural properties of apolipoprotein C-II amyloid fibrils, the The University of Melbourne, Parkville insisted(3).

Resveratrol, a phytochemical in the class of Stilbenoids, found abundantly in grape and blueberry also inhibited the process of amyloid formation by the normally soluble hormone islet amyloid polypeptide (IAPP) which contributed to β-cell death in type 2 diabetes, according to the Stony Brook University(4).

Vitamin C, one of the powerful may benefit patients with amyloidosis, through its free radical scavenger activity(5).

According to Dr. Ravid M and colleagues, in animal model, ascorbic acid partially restored the amyloid-degrading activity in dose-dependent manner(6).

The effectiveness of Green tea, Orange and Grape may serve as cornerstones of pharmaceutical target for further studies in production of a potential medication for reduced risk, complications and treatment of Renal Amyloidosis with little or no adverse effects.

People who are at high risk of Renal Amyloidosis due to aging, weaken reno function... should drink at least one serving daily and women with Renal Amyloidosis should drink no more than 4 servings daily, depending to digestive toleration.

Life style and diet pattern change are necessary.

All Forms of Arthritis are Curable

You Can Eliminate Osteoarthritis

By addressing the Underlying Causes through Clinical Trials and Studies

Ovarian Cysts And PCOS Elimination

Holistic System In Existence That Will Show You How To

Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Super foods Library, Eat Yourself Healthy With The Best of the Best Nature Has to Offer

References

(1) The polyphenol (-)-epigallocatechin-3-gallate prevents apoA-IIowa amyloidosis in vitro and protects human embryonic kidney 293 cells against amyloid cytotoxicity by Nakajima H1,2, Nishitsuji K1, Kawashima H3, Kuwabara K1,2, Mikawa S2, Uchimura K4, Akaji K3, Kashiwada Y5, Kobayashi N6, Saito H2,Sakashita N1.(PubMed)

(2) Green tea extract as a treatment for patients with wild-type transthyretin amyloidosis: an observational study by Siepen FA1, Bauer R1, Aurich M1, Buss SJ1, Steen H1, Altland K2, Katus HA1, Kristen AV1(PubMed)

(3) Fluphenazine·HCl and Epigallocatechin Gallate Modulate the Rate of Formation and Structural Properties of Apolipoprotein C-II Amyloid Fibrils by Zlatic CO1, Mao Y1, Ryan TM1, Mok YF1, Roberts BR1, Howlett GJ1, Griffin MD1.(PubMed)

(4) Mutational analysis of the ability of resveratrol to inhibit amyloid formation by islet amyloid polypeptide: critical evaluation of the importance of aromatic-inhibitor and histidine-inhibitor interactions by Tu LH1, Young LM, Wong AG, Ashcroft AE, Radford SE, Raleigh DP.(PubMed)

(6) Ascorbic acid-induced regression of amyloidosis in experimental animals by Ravid M, Chen B, Bernheim J, Kedar I.(PubMed)

Most Common Diseases of elder: Respiratory Pleural disease: Pleural effusion Treatment Caused by Pneumonia

B.6.1. Treatments in conventional medicine perspective

Pleural effusion Caused by Pneumonia
Antibiotics are the mosst efective medication used to treat pneumonia. Other medication used conjucntion with antibiotics can be helpful in relieveing breathing and symptoms.
1. Antibiotics
Pneumonia caused by bacterial pathogens is the leading cause of mortality in children in low-income countries. In a review to identify effective antibiotics for community acquired pneumonia (CAP) in children by comparing various antibiotics, conducted by All India Institute of Medical Sciences, Ansari Nagar, indicated that for treatment of ambulatory patients with CAP, amoxycillin is an alternative to co-trimoxazole. With limited data on other antibiotics, co-amoxyclavulanic acid and cefpodoxime may be alternative second-line drugs. For severe pneumonia without hypoxia, oral amoxycillin may be an alternative to injectable penicillin in hospitalised children; however, for ambulatory treatment of such patients with oral antibiotics, more studies in community settings are required. For children hospitalised with severe and very severe CAP, penicillin/ampicillin plus gentamycin is superior to chloramphenicol. The other alternative drugs for such patients are ceftrioxone, levofloxacin, co-amoxyclavulanic acid and cefuroxime. Until more studies are available, these can be used as a second-line therapy(80).
Side effects are not limit to soft stools or diarrhea, mild stomach upset, etc.
2. Antivirals
Parainfluenza viruses affect the upper respiratory tract in all age group patients, in children aged 6 months to 3 years in particular. In the study to investigate the antiviral activity of Ingavirin (2-(imidazole-4-yl) ethanamide of pentandioic-1,5 acid) on a model of parainfluenza infection in Syrian hamsters, showed that the drug was shown to restrict the infectious process in animal lung tissue. This restriction manifested itself as reductions in the infectious titer of parainfluenza virus in the lung tissue, in the degree of pulmonary edema and tissue cell infiltration, and in virus-specific lesion of bronchial epithelial cells(81). Side effects are not limit to dizziness, fatigue, joint or muscle pain, headache, dry mouth, nausea, vomiting, loss of appetite, weight loss, insomnia, etc.
3. Other Supportive treatment to reduce symptoms, include
Fever and pain reducers such as aspirin, ibuprofen, naproxen or acetaminophen, etc. and cough medicine.

All Forms of Arthritis are Curable
You Can Eliminate Osteoarthritis
By addressing the Underlying Causes through Clinical Trials and Studies

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Super foods Library, Eat Yourself Healthy With The Best of the Best Nature Has to Offer

Sources
(80) http://www.ncbi.nlm.nih.gov/pubmed/20238334
(81) http://www.ncbi.nlm.nih.gov/pubmed/22834146

Most Common Diseases of elder: Respiratory Pleural disease: Pleural effusion treatment Pleural effusion Caused by Congestive heart failure

B.6.1. Treatments in conventional medicine perspective
Treatments in conventional medicine perspective are depending to the underlined causes of the diseases with an aim to produce enough oxygen to the lung for the body to function.

Pleural effusion Caused by Congestive heart failure
Congestive heart failure is a condition of which the heart can’t pump enough blood to the body’s needs.
1. Nonsurgical treatment
1.1. Medication
The renin-angiotensin-aldosterone system is a well-established therapeutic target in the treatment of heart failure (HF). Substantial advances have been made with existing agents-angiotensin-converting enzyme (ACE) inhibitors, angiotensin II-receptor blockers (ARBs), and mineralocorticoid-receptor antagonists (MRAs)-and new data continue to emerge. According to teh study by the Medical Research Institute, University of Dundee, ARBs have been shown to be a beneficial alternative to ACE inhibitors in HFrEF, but their value when added to ACE inhibitors has been questioned. Upstream, direct renin blockade with aliskiren is being pursued in two large trials of HF, despite the premature halting of a third study. A substantial, unmet need remains in patients who have HF with preserved ejection fraction (HFpEF)(70).
2. Surgical treatments
2.1. Implantation of medical devices
a. Ventricular assist device (VAD).
Ventricular assist devices (VADs) have become an established therapeutic option for patients with end-stage heart failure. There is a reprot of six cases of VAD patients with clinical presentation of heart failure at different times after implantation and describe the mechanisms involved(71)
b. Cardiac resynchronization therapy (CRT) device (biventricular cardiac pacemaker).
In the study to elucidate the role of nuclear medicine imaging in the selection of candidates for cardiac resynchronization therapy (CRT) and in the evaluation of CRT effectiveness of a total of 28 patients (19 male and 9 female) with dilated cardiomyopathy (DCM) and heart failure (HF), found that all patients after CRT were divided into three groups. The first group included 10 patients with LVEF increased by more than 10 % (hyperresponders), the 2nd group included 11 patients with an increase in EF of more than 5 % but less than 10 % (responders) and third group consisted of 7 males whose LVEF remained unchanged or worsened compared with pre-operative values (nonresponders). Prior to CRT, no statistically significant differences were found between groups in hemodynamic parameters (EF, EDV, ESV, SV), intra- and interventricular dyssynchrony, as well as in the midsize of perfusion defects. Following long-term CRT, we found increase in LVEF and decrease in average size of perfusion defects in groups of hyperresponders and responders (p < 0.05). Results of SPECT with 123I-BMIPP, performed prior to CRT, showed that nonresponders had more pronounced disturbance of myocardial metabolism compared with the group of hyperresponders (20 vs. 14.7 %, p < 0.05)(72).
c. Internal cardiac defibrillator (ICD)
The Kalmar County Hospita, presented a case report and a selective review of pertinent literature retrieved by a PubMed search, including two up-to-date consensus documents. One-third to two-thirds of all ICD patients receive defibrillation therapy in the final days of their lives. Patients and their physicians rarely discuss deactivating the ICD. Automatic defibrillation therapy in a terminally ill patient with an ICD is painful and distressing, serves no medical purpose, and should be avoided. This issue should be discussed with ICD patients and their families. Institutions caring for terminally ill patients, as well as cardiology units where ICD patients are treated, should develop ethically and legally well-founded protocols for dealing with the question of ICD deactivation(73).
d. Rotary blood pumps
Rotary blood pumps are increasingly recognized as mainstream therapy for severely symptomatic heart failure. Carefully targeted refinements in patient selection and postoperative care have substantially reduced the adverse event burden. The Oxford University Hospitals Trust, John Radcliffe Hospital, suggested that It should focus on the choice between pump versus palliative care for the thousands of patients of all age groups who are judged ineligible for transplantation. Comprehensive healthcare systems must consider contemporary evidence and provide the most symptomatic of heart failure patients with effective care(74).
2.2. Surgical treatments
a. Heart valve repair or replacement.
The aim of the surgery is to relieve symptoms and improve quality of life of patients with congestive heart failure. In the study to o describe the pathophysiology of functional tricuspid regurgitation, summarize the current reports favoring a more aggressive approach toward tricuspid valve surgery, and discuss the emerging role of tricuspid valve annuloplasty with left ventricular assist device (LVAD) implantation, found that the presence of significant tricuspid regurgitation, whether in the context of mitral valve disease or heart failure, should no longer be treated with 'surgical abstention'. Whether the surgical correction of tricuspid regurgitation in left heart disease can definitively improve clinical outcomes should be addressed by prospective clinical trials(75). Other in the study to evaluate the long-term (5-year) safety and efficacy of mitral valve surgery with and without the CorCap cardiac support device (Acorn Cardiovascular, St Paul, Minn) in patients with dilated cardiomyopathy and New York Heart Association class II-IV heart failure, indicated that the data provide evidence supporting mitral valve repair in combination with the Acorn CorCap device for patients with nonischemic heart failure with severe left ventricular dysfunction who have been medically optimized yet remain symptomatic with significant mitral regurgitation(76).
b. Coronary bypass surgery
According to the study by the University of California, in the study to quantify the effects of a novel implantable hydrogel (Algisyl-LVR™) treatment in combination with coronary artery bypass grafting (i.e. Algisyl-LVR™+CABG) on both LV function and wall stress in heart failure patients. The data supportedthe novel concept that Algisyl-LVR™+CABG treatment leads to decreased myofiber stress, restored LV geometry and improved function(77)..
c. Heart transplant
Only for patients with severe congestive heart failure and other treatments have failed. According to the Ohio State University, Columbus, Avoidance of the clinical syndrome of acute right-sided heart failure after heart transplantation is, unfortunately, not possible. Clinical experience and the literature certainly suggest that a significant factor in the successful management of right ventricular (RV) failure is recipient selection. Moreover, threshold hemodynamic values beyond which RV failure is certain to occur and heart transplantation is contraindicated do not exist.Only through careful preoperative planning can this life-threatening condition be managed in the postoperative period(78).
d. Myectomy
Patient with blockage that occurs in hypertrophic cardiomyopathy may meed myectomy, if all medication have failed. There is a report of a 38-year-old woman of Hypertrophic Obstructive Cardiomyopathy, HOCM complicated with lung edema and cardiac arrest due to acute left heart failure. Intraventricular pressure gradient showed 125 mmHg in previous study, and echocardiogram demonstrated evidences suggestive of terminal-staged HOCM. After unsuccessful attempts of intravenous propranolol administration, emergency myectomy of left ventricular outflow tract was carried out. Postoperative course was uneventful, and intraventricular pressure gradient was relieved. The patient is now asymptomatic without medication after 1 years of operation. This case suggests that emergency myectomy may be a choice to relieve refractory congestive heart failure in patient with HOCM(79).

Sources
(70) http://www.ncbi.nlm.nih.gov/pubmed/23319100
(71) http://www.ncbi.nlm.nih.gov/pubmed/23374971
(72) http://www.ncbi.nlm.nih.gov/pubmed/23456177
(73) http://www.ncbi.nlm.nih.gov/pubmed/23152737
(74) http://www.ncbi.nlm.nih.gov/pubmed/23463973
(75) http://www.ncbi.nlm.nih.gov/pubmed/22327290
(76) http://www.ncbi.nlm.nih.gov/pubmed/21269649
(77) http://www.ncbi.nlm.nih.gov/pubmed/23394895
(78) http://www.ncbi.nlm.nih.gov/pubmed/11583860
(79) http://www.ncbi.nlm.nih.gov/pubmed/8940847

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