Saturday, April 2, 2016

The Fabulous Smoothie of Strawberry, Herbal Motherwort Tea and Green Tea for Prevention and Treatment of Autoimmune nephritis

Kyle J. Norton(Scholar, Master of Nutrients), all right reserved.
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.


The smoothie for prevention and treatment of autoimmune nephritis  
Yield: 2 servings (about 8 ounces each)
1/4 cup strawberry
1 cup herbal Motherwort tea(Make from 4 grams of Motherwort  and a cup of hot water lipped for 5 minutes. Set aside for cooling to room temperature)
1 cup green tea drink (Make from 4 grams of green tea, and a cup of hot water lipped for 5 minutes. Set aside for cooling to room temperature)
1. Place all ingredients in a blender and puree about 1 minute
2. Blend on high speed about 1 minute or until the mixture is thick and the ice is well crushed. Add more green tea drink if needed
3. Serve immediately

Autoimmune nephritis is a kidney inflammatory disorder caused by immune disorder. According to Centro Nacional de Investigaciones Cardiovasculares, stimulation of regulator of adipocyte development PPARγ and mediation of the biological effects of retinoids RXRα may provide a potential strategy to avoid autoimmunity against dying cells and to attenuate SLE(1).


The finding the natural ingredients for improvement of autoimmune nephritis without induced adverse effects is considered as a dream of many scientist. Unfortunately, many compounds found effective in initial studying failed to confirm the potential in large sample size and multi center. Some even produce conflicted results in second and further studies.

Recent studies reported by some renowned institutions suggested that Green tea(Vitamin E), Tomato(Vitamin A)  may process a potential effect as a therapeutic ingredients for reduced risk and treatment of autoimmune nephritis.

Green tea has been a precious drink in traditional Chinese culture and used exceptional in socialization for more than 4000 thousand years. Due to its commercial values and health effects, green tea now has been cultivated all over the world in suitable climate. According to the Shizuoka University, in the study of one-month-old MRL-Faslprcg/Faslprcg mice fed diets containing 2% green tea powder (GTP) for 3 months, showed that the survival of mice was significantly prolonged by GTP feeding for 6 months, through attenuated the progression of autoimmune disease, lupus-like
syndrome, including glomerulonephritis(2).Epigallocatechin-3-gallate, a major constituent of green tea, in mice induced cisplatin nephrotoxicity exhibited anti-oxidant, anti-inflammatory, and anti-tumorigenic effects through regulating kidney cell apoptosis in some mechanisms, including expression of Bax and Bcl-2(3) and pro inflammatory pathways NF-kappaB.(4).

Leonurine (LEO), an alkaloid isolated from Leonurus cardiaca(Motherwort),exhibited significant effects such as antioxidant, anticoagulant, and anti-apoptosis against renal tissue damage, production of pro inflammatory cytokines, via decreasing cellular ROS production(5). In chronic kidney inflammatory disease (CKD), the antioxidant also expressed anti inflammatory reactions and oxidative stress via modified the cytokine expression of TGF-β, TNF-α, IL-6 and IL-1β and suppressed the phosphorylation of Smad3 involved in transmitting chemical signals from the cell surface to the nucleus(6).

Strawberry is a genius of Fragaria × ananassa belongings to the family Roseaceae, grown all over the world with suitable climate for commercial profits and for health benefits. According to Dr. Ibrahim DS and Dr. Abd El-Maksoud MA, strawberry extracts inhibited diabetic nephropathy induced clinical syndrome of albuminuria, hypertension and progressive renal insufficiency through its anti-diabetic, antioxidant, anti-inflammatory and anti-apoptotic activities(7).

This discover of the effectiveness of  Strawberry, Herbal Motherwort Tea and Green Tea  may serve as cornerstones of pharmaceutical target for further studies in production of a potential medication for reduced risk and treatment of autoimmune nephritis little or no adverse effects.

People who are at high risk of  autoimmune nephritis due to family history, obesity,..... should drink at least one serving daily and people with autoimmune nephritis should drink the smoothie as much as they can, depending to digestive toleration.
Life style and dietary pattern change are recommended.


References
(1) Autoimmune kidney disease and impaired engulfment of apoptotic cells in mice with macrophage peroxisome proliferator-activated receptor gamma or retinoid X receptor alpha deficiency. by Roszer T1, Menéndez-Gutiérrez MP, Lefterova MI, Alameda D, Núñez V, Lazar MA, Fischer T, Ricote M.(PubMed)
(2) Inhibitory effects of autoimmune disease by green tea in MRL-Faslprcg/Faslprcg mice by Sayama K1, Oguni I, Tsubura A, Tanaka S, Matsuzawa A.(PubMed)
(3) Epigallocatechin-3-gallate protects against cisplatin nephrotoxicity by inhibiting the apoptosis in mouse by Zou P1, Song J1, Jiang B1, Pei F1, Chen B1, Yang X1, Liu G2, Hu Z1.(PubMed)
(4) Epigallocatechin-3-gallate activates Nrf2/HO-1 signaling pathway in cisplatin-induced nephrotoxicity in rats by Sahin K1, Tuzcu M, Gencoglu H, Dogukan A, Timurkan M, Sahin N, Aslan A, Kucuk O.(PubMed)
(5) Leonurine ameliorates LPS-induced acute kidney injury via suppressing ROS-mediated NF-κB signaling pathway by Xu D1, Chen M2, Ren X3, Ren X4, Wu Y5.(PubMed)
(6) Leonurine ameliorates kidney fibrosis via suppressing TGF-β and NF-κB signaling pathway in UUO mice by Cheng H1, Bo Y2, Shen W1, Tan J1, Jia Z1, Xu C3, Li F4.(PubMed)
(7) Effect of strawberry (Fragaria × ananassa) leaf extract on diabetic nephropathy in rats by Ibrahim DS1, Abd El-Maksoud MA1.(PubMed)

Most Common Diseases of elder: Respiratory Pleural disease: Pleural Plaques - The Diet

Kyle J. Norton(Scholar and Master of Nutrients, all right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

                                          Respiratory Disease

Respiratory Disease is defined as medical conditions, affecting the breathing organ and tissues including Inflammatory lung disease, Obstructive lung diseases, Restrictive lung diseases, Respiratory tract infections, trachea, bronchi, bronchioles, alveoli, the nerves and muscles breathing, etc,.

                   Pleural disease: Pleural Plaques

The pleura is a thin tissue covered by a layer of cells (mesothelial cells) that surrounds the lungs and lines the inside of the chest wall.
Pleural plaques is a medical condition as a result of exposure to asbestos that lead to accumulated plagues within the pleural cavity(a). Many diseases such as pneumonia, breast cancer, and heart failure can affect the pleural space.,therefore, it is often a secondary effect of another disease process.

                                           The Preventive Diet

The only way to prevent pleural plaques and other asbestos-related lung damage is to eliminate asbestos exposure. Diagnosis early such as routine chest radiographs may help to prevent asbesto related lung diseases.According to the study by the UCLA Medical Center, although CT scans can demonstrate abnormalities, there are minimal data suggesting that these findings are of physiologic significance. This observation would be similar to the CT detection of unsuspected pleural plaques on routine chest radiographs in workers or others exposed to asbestos fiber who remain clinically asymptomatic with normal lung function. Further radiographic progression and clinical and/or functional impairment would not be generally expected for localized pleural plaques and/or radiographically negative, 0/1, 1/0, or 1/1 asbestosis. Radiographic progression has infrequently been noted following withdrawal from exposure. Understanding of underlying physiologic mechanisms and attention to the meaning of pathologic-physiologic relationships can help improve the utilization of pulmonary function testing for preventing occupational lung disease(26).

In the study of 86 men with sixty subjects with asbestos-related disorders (asbestosis: 18, diffuse pleural thickening (DPT): 16, pleural plaques (PPs): 26) and twenty six age- and gender-matched normal individuals to assess oxidative stress and lung inflammation in vivo, found that subjects with asbestosis had raised EBC markers of oxidative stress compared with normal controls [8-isoprostane (geometric mean (95% CI) 0.51 (0.17-1.51) vs 0.07 (0.04-0.13) ng/ml, p<0.01); hydrogen peroxide (13.68 (8.63-21.68) vs 5.89 (3.99-8.69) microM, p<0.05), as well as increased EBC total protein (17.27 (10.57-28.23) vs 7.62 (5.13-11.34) microg/ml, p<0.05), and fractional exhaled nitric oxide (mean+/-SD) (9.67+/-3.26 vs 7.57+/-1.89ppb; p<0.05). EBC pH was lower in subjects with asbestosis compared with subjects with DPT (7.26+/-0.31 vs 7.53+/-0.24; p<0.05). There were no significant differences in exhaled carbon monoxide, EBC total nitrogen oxides and 3-nitrotyrosine between any of the asbestos-related disorders, or between these and controls (27).

Since in asbestos-related disorders, markers of inflammation and oxidative stress are significantly elevated in subjects with asbestosis compared with healthy individuals but not in pleural diseases, then intake of antioxidants should be helpful.

Green tea, turmeric and grape seek and skin contain powerful natural sources of antioxidants in targeting oxidative stress with antioxidants or boosting the endogenous levels of antioxidants is likely to be beneficial in the treatment of inflammatory respiratory diseases. Ac coding to the study by the dietary polyphenols (curcumin, resveratrol, green tea, catechins/quercetin), have been reported to control nuclear factor-kappaB (NF-kappaB) activation, regulation of glutathione biosynthesis genes, chromatin remodeling, and hence inflammatory gene expression(27a).

Other study also indicated that Turmeric is known for its multiple health restoring properties, and has been used in treating several diseases including several respiratory disorders. Turmeric is a common spice used in the culinary preparations in South and East Asian countries. The active component of turmeric is curcumin, a polyphenolic phytochemical, with anti-inflammatory, antiamyloid, antiseptic, antitumor, and antioxidative properties(28).
All Forms of Arthritis are Curable
You Can Eliminate Osteoarthritis
By addressing the Underlying Causes through Clinical Trials and Studies

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Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

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Friday, April 1, 2016

Most Common Disease of 50plus: The Clinical trials and Studies of Musculo-Skeletal disorders(MSDs) - Osteoarthritis: Diseases associated to

Kyle J. Norton (Scholar)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

Musculoskeletal disorders (MSDs) are medical condition mostly caused by work related occupations and working environment, affecting patients’ muscles, joints, tendons, ligaments and nerves and developing over time. A community sample of 73 females and 32 males aged 85 and over underwent a standardised examination at home. Musculoskeletal pain was reported by 57% of those interviewed. A major restriction of joint movement range was frequent in the shoulder but uncommon in other joints(1).

Types of Musculo-Skeletal disorders in elder(2)

1. Osteoarthritis
2. Gout
3. Rheumatoid Arthritis
4. Polymalagia Arthritis
5. Cervical myleopathy and spinal canal stenosis
6. Osteoporosis
7. Low back pain
8. Fibromyalgia                  



                                                      Osteoarthritis


Osteoarthritis (OA), a form of arthritis, is defined as a condition of as a result of aging causes of wear and tear on a joint, affecting over 25 million people in the United States in alone. University of Porto Medical School indicated that one must understand the differences in prevalence and incidence estimates of osteoarthritis (OA), according to case definition, in knee, hip and hand joints(3).
The characteristics of osteoarthritis are aching pain(5), stiffness(6), or difficulty of moving the joint or joints(7). The pain usually gets worse in change of weather, at night and in the advanced diseases, the pain can occur even at rest(8). Today management of osteoarthritis (OA) focuses on pain relief and improved physical function through pharmacological, non pharmacological, and surgical treatments(4).

              Diseases associated with osteoarthritis


Researchers suggested that OA is not simply a disease related to aging or mechanical stress of joints but rather a “metabolic disorder(70)(71)” interrelated to lipid, metabolic, and humoral mediators(70). Indeed, OA has been linked not only to obesity(46)(47) but also to other cardiovascular risk factors(72)(73), namely, diabetes(74), dyslipidemia, hypertension, and insulin resistance(75).
Most people with osteoarthritis also suffer from one or more of below
1. Hypertension
According to the University Health Network Research Institute, the economic burden incurred by RA significantly exceeds that related to OA and HBP(76)(77).

2. Cardiovascular disease
According to Erasmus University Medical Centre, there is an associations of atherosclerosis with osteoarthritis of the knee and hand joints in women(72)(73)(78).

3. Peripheral vascular disease
According to Himchan Hospital, patient with due to osteoarthritis are associated to risk of asymptomatic peripheral vascular disease(80). The average vessel wall thickness of the popliteal artery was 1.09 mm in patients with generalized OA, and 0.96 mm in the matched normal reference population(79).

4. Congestive heart failure
Hypertension, diabetes, and older age have shown to increased risk of Congestive heart failure modestly(81). Etoricoxib, an annti-inflammatory painkillers showed a statistically significant inhibition at 90 mg in patients with osteoarthritis and rheumatoid arthritis(82).

5. Renal function impairment
According to the Southampton University Hospitals NHS Trust, pain pharmacotherapies osuch as osteoarthritis (OA) or mixed OA and rheumatoid arthritis may increase the risk of adverse events in patients with concurrent cardiovascular (CV) or renal disease(83). Median excretion of pyridinoline and deoxypyridinoline in the OA patients as a whole was raised above values found in a healthy control population(84).

6. Diabetes
Several epidemiological and experimental data support the hypothesis that diabetes could be an independent risk factor for osteoarthritis (OA)(76)(85).

7. Respiratory disease
People with Respiratory disease is also at a higher risk to develop osteoarthritis (OA), such as chronic cough and bilateral infiltrates on chest roentgenogram(86).

8. High serum of Cholesterol
There is an association between high serum cholesterol level and both knee and generalized OA, according to the study of 113 females and 133 males with average ages 46 14.2 and 51.54 16.0 years by King Khalid University Hospital(87).

Arthritis Is Curable
You Can Eliminate Osteoarthritis
By addressing the Underlying Causes through Clinical Trials and Studies

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

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References

(1) Prevalence of rheumatic symptoms, rheumatoid arthritis, ankylosing spondylitis, and gout in Shanghai, China: a COPCORD study by Dai SM1, Han XH, Zhao DB, Shi YQ, Liu Y, Meng JM.(PubMed)
(2) Musculoskeletal Disorders in the Elderly by Ramon Gheno, Juan M. Cepparo, Cristina E. Rosca,1 and Anne Cotten(PMC)
(3) The effect of osteoarthritis definition on prevalence and incidence estimates: a systematic review by Pereira D1, Peleteiro B, Araújo J, Branco J, Santos RA, Ramos E.(PubMed)
(4) Effect of therapeutic aquatic exercise on symptoms and function associated with lower limb osteoarthritis: systematic review with meta-analysis by Waller B1, Ogonowska-Slodownik A2, Vitor M3, Lambeck J4, Daly D5, Kujala UM6, Heinonen A7.(PubMed)
(5) Effects of therapeutic ultrasound on pain, physical functions and safety outcomes in patients with kneeosteoarthritis: A systematic review and meta-analysis by Zhang C1, Xie Y2, Luo X3, Ji Q3, Lu C3, He C4, Wang P3.(PubMed)
(6) Oral intake of purple passion fruit peel extract reduces pain and stiffness and improves physical function in adult patients with knee osteoarthritis by Farid R1, Rezaieyazdi Z, Mirfeizi Z, Hatef MR, Mirheidari M, Mansouri H, Esmaelli H, Bentley G, Lu Y, Foo Y, Watson RR.(PubMed)
(7) Functional ability, mobility, and pain before and after knee replacement in patients aged 75 and older: a cross-sectional study by Limnell K1, Jämsen E, Huhtala H, Jäntti P, Puolakka T, Jylhä M.(PubMed)
(8) The symptoms of OA and the genesis of pain by David J. Hunter, MBBS PhD,1,2 Jason J. McDougall, BSc PhD,3 and Francis J. Keefe4(PubMed)

(70) Osteoarthritis: another component of metabolic syndrome? by Velasquez MT1, Katz JD.(PubMed)
(71) [Metabolic syndrome and a course of osteoarthrosis].[Article in Russian] by Korochina IE, Bagirova GG.(PubMed)

(72) Risk of cardiovascular disease in patients with osteoarthritis: a prospective longitudinal study. by Rahman MM1, Kopec JA, Anis AH, Cibere J, Goldsmith CH.(PubMed)
(73) Cardiovascular disease and osteoarthritis: common pathways and patient outcomes. by Fernandes GS1, Valdes AM.(PubMed)
(74) Risk of Type 2 Diabetes among Osteoarthritis Patients in a Prospective Longitudinal Study by Rahman MM1, Cibere J2, Anis AH3, Goldsmith CH4, Kopec JA5.(PubMed)
(75) Osteoarthritis—the impact of a serious disease by F. C. Breedveld
(76) Bone loss at subchondral plate in knee osteoarthritis patients with hypertension and type 2 diabetes mellitus. by Wen CY1, Chen Y, Tang HL, Yan CH, Lu WW, Chiu KY.(PubMed)
(77) The economic burden associated with osteoarthritis, rheumatoid arthritis, and hypertension: a comparative study. by Maetzel A1, Li LC, Pencharz J, Tomlinson G, Bombardier C; Community Hypertension and Arthritis Project Study Team.(PubMed)
(78) Association of atherosclerosis with presence and progression of osteoarthritis: the Rotterdam Study by Hoeven TA1, Kavousi M, Clockaerts S, Kerkhof HJ, van Meurs JB, Franco O, Hofman A, Bindels P, Witteman J, Bierma-Zeinstra S.(PubMed)
(79) Positive association between increased popliteal artery vessel wall thickness and generalized osteoarthritis: is OA also part of the metabolic syndrome? by Kornaat PR1, Sharma R, van der Geest RJ, Lamb HJ, Kloppenburg M, Hellio le Graverand MP, Bloem JL, Watt I.(PubMed)
(80) Asymptomatic peripheral vascular disease in total knee arthroplasty: preoperative prevalence and risk factors. by Park IH1, Lee SC, Park IS, Nam CH, Ahn HS, Park HY, Gondalia VH, Jung KA.(PubMed)
(81) Baseline factors associated with congestive heart failure in patients receiving etoricoxib or diclofenac: multivariate analysis of the MEDAL program by Krum H1, Curtis SP, Kaur A, Wang H, Smugar SS, Weir MR, Laine L, Brater DC, Cannon CP.(PubMed)
(82) Baseline factors associated with congestive heart failure in patients receiving etoricoxib or diclofenac: multivariate analysis of the MEDAL program by Krum H1, Curtis SP, Kaur A, Wang H, Smugar SS, Weir MR, Laine L, Brater DC, Cannon CP.(PubMed)
(83) Pain pharmacotherapy in patients with inflammatory arthritis and concurrent cardiovascular or renal disease: a Cochrane systematic review. by Marks JL1, van der Heijde DM, Colebatch AN, Buchbinder R, Edwards CJ.(PubMed)
(84) Urinary excretion of pyridinium crosslinks of collagen correlated with joint damage in arthritis by Astbury C1, Bird HA, McLaren AM, Robins SP.(PubMed)
(85) Diabetes-induced osteoarthritis: from a new paradigm to a new phenotype by Berenbaum F1.(PubMed)
(86) [Pulmonary infiltrates with blood eosinophilia in a 62-year-old patient].[Article in German] by Kohlhäufl M1, Weber N, Morresi-Hauf A, Geiger D, Raith H, Häussinger K.(PubMed)
(87) Radiographic osteoarthritis and serum cholesterol by Al-Arfaj AS1.(PubMed)

The smoothie of Cooked Tomato, Peanut and Olive for reduced complications and Treatment of Polycystic kidney disease (Renal cystic disease)

Kyle J. Norton(Scholar, Master of Nutrients), all right reserved.
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

The smoothie for prevention and treatment of  polycystic kidney disease (Renal cystic disease) 
Yield: 2 servings (about 8 ounces each)
3/4 cup cooked tomato
1/2 cup peanut
1/4 cup olive
1 cup rice milk

1. Place all ingredients in a blender and puree about 1 minute
2. Blend on high speed about 1 minute or until the mixture is thick and the ice is well crushed.
3. Serve immediately

The finding of a natural source for treatment of Polycystic kidney disease (Renal cystic disease) has been running into many obstacles, many ingredients showed initially with promising result in animal studies have not produced same potentials in large sample size and mutli centers human trials.

Polycystic Kidney Disease is an inherited diseases with fluid-filled cysts developed on the kidney. According to the University of Kansas Medical Center, the disease is associated to risk factors of aging, in older persons with multiple cysts probably induced by potassium deficiency, congenital disorders, metabolic diseases, and toxic renal injury(1).

Recent studies back by well known institutions proposed, Cooked Tomato, Peanut and Olive may be the next generation of natural ingredients for reduced complications and treatment of Polycystic kidney disease.

Vitamin B3 , also known as niacin, is a water-soluble vitamin.Vitamin B3 found abundantly in peanut may benefit patient with polycystic kidney disease(2). According to C.J. Janovy, administration of Vitamin B3 to a neonate, toddler or adolescent will effectively prevent or delay cyst formation and can be used for a lifetime(2).
Dr. Al Adlouni A and Dr. Hertig A. Said, "Vitamin B3 exhibited anti  autosomal dominant effect  involed the develop of polycystic kidney disease"(3).

Omaga 3 fatty acids found abundantly in flax seed also attenuated the progression of polycystic kidney disease, through alternation of multiple steps in PKD pathogenesis(4). According to the University of Guelph, mice fed with an n-3 fatty acid-enriched diet (MaxEPA) for 60 days, showed a marked decrease in the proportion of kidney area occupied by cysts in male but not in female rat(5).
Dr. Yamaguchi T and colleagues in the study led by the University of Manitoba, said,"Dietary flax oil may therefore reduce disease progression via mitigation of oxylipin abnormalities"(6) in patients with renal diseases.

Retinoic acids all-trans retinoic acid (AT-RA) and 9-cis retinoic acid (9C-RA) with function as of vitamin A suppressed the activation of the poly cystic kidney disease-1 (PKD1) promoter in's attenuated the diseases' progression(7). 
 Dr.Yamane A and professors at the Gunma University Graduate School of Medicine, said," A 63-year-old APL patient, complicated by Child-Pugh class A liver cirrhosis and polycystic kidney (creatinine 3.2 mg/dL), was successfully treated with 45 mg/m(2)/day of all-trans retinoic acid (ATRA)"(8).

The effectiveness of  Cooked Tomato, Peanut and Olive may serve as cornerstones of pharmaceutical target for further studies in production of a potential medication for reduced risk, complications and treatment of polycystic kidney disease (Renal cystic disease) with little or no adverse effects.

People who are at high risk of polycystic kidney disease (Renal cystic disease) due to aging, weaken reno function... should drink at least one serving daily and women with polycystic kidney disease (Renal cystic disease) should drink no more than 4 servings daily, depending to digestive toleration.

Life style and diet pattern change are necessary.



Refeneces
(1) Polycystic kidney disease: etiology, pathogenesis, and treatment by Martinez JR1, Grantham JJ.(PubMed)
(2) Vitamin B3 holds promise for treating polycystic kidney disease, research suggests, June 17, 2013
By C.J. Janovy
(3) [Vitamin B3 to prevent autosomal dominant polycystic kidney disease].[Article in French] by Al Adlouni A1, Hertig A2.(PubMed)
(4) Evidence for a role of proteins, lipids, and phytochemicals in the prevention of polycystic kidney disease progression and severity by Maditz KH1, Gigliotti JC, Tou JC.(PubMed)
(5) Effects of dietary supplementation with n-3 fatty acids on kidney morphology and the fatty acid composition of phospholipids and triglycerides from mice with polycystic kidney disease by Yamaguchi T1, Valli VE, Philbrick D, Holub B, Yoshida K, Takahashi H.(PubMed)
(6) Dietary flax oil rich in α-linolenic acid reduces renal disease and oxylipin abnormalities, including formation of docosahexaenoic acid derived oxylipins in the CD1-pcy/pcy mouse model of nephronophthisis by Yamaguchi T1, Devassy JG1, Gabbs M2, Ravandi A3, Nagao S4, Aukema HM5.(PubMed)
(7) Retinoic acid-dependent activation of the polycystic kidney disease-1 (PKD1) promoter by Islam MR1, Puri S, Rodova M, Magenheimer BS, Maser RL, Calvet JP.(PubMed)
(8) Successful treatment by all-trans retinoic acid in a patient with acute promyelocytic leukemia complicated by liver cirrhosis and polycystic kidney by Yamane A1, Tsukamoto N, Saitoh T, Uchiumi H, Handa H, Karasawa M, Nojima Y, Murakami H.(PubMed)

Most Common Diseases of 50plus: Respiratory Pleural disease: Pleural Plaques - The Diagnosis

Kyle J. Norton(Scholar and Master of Nutrients, all right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

                                          Respiratory Disease

Respiratory Disease is defined as medical conditions, affecting the breathing organ and tissues including Inflammatory lung disease, Obstructive lung diseases, Restrictive lung diseases, Respiratory tract infections, trachea, bronchi, bronchioles, alveoli, the nerves and muscles breathing, etc,.

                Pleural disease: Pleural Plaques

The pleura is a thin tissue covered by a layer of cells (mesothelial cells) that surrounds the lungs and lines the inside of the chest wall.
Pleural plaques is a medical condition as a result of exposure to asbestos that lead to accumulated plagues within the pleural cavity(a). Many diseases such as pneumonia, breast cancer, and heart failure can affect the pleural space.,therefore, it is often a secondary effect of another disease process.

                               Diagnosis

If you are experience certain of above symptoms and your doctor suspect that you may have develop pleural plaques, after recording you family history including occupation and a complete physical examination, including listen to your lung to test for asbestosis, as the lungs affected by asbestosis often produce a particular dry, crackling sound and pulmonary function test. Other tests which your doctor orders may include
1. Chest X-ray and CT scans
Pleural plaques are asymptomatic focal thickenings of the pleura and considered the hallmark of asbestos exposure. In a retrospective study by the Nagoya University Graduate School of Medicine using chest CT scans of 140 Japanese asbestos-exposed construction workers who have probable or definite findings of pleural plaque on CXR; firstly, we proposed plaque morphology-based classification for CXR findings, and then we examined if those classified findings could be confirmed as pleural plaques on CT scans. Our morphology-based classification of pleural plaque findings included nine types. The percentages of confirmed pleural plaques on CT scans by type (number of confirmed pleural plaque on CT/number of observed on CXR) were 93% (40/43) for straight, 89% (56/63) for diamond, 88% (7/8) for double, 83% (19/23) for tapered medially, 80% (20/25) for parallel, 77% (23/30) for crescent, 79% (11/14) for tenting, 72% (18/25) for tapered-laterally (long type), and 0% (0/9) for tapered-laterally (short type). When added to the ILO classification, morphology-based classification of CXR pleural plaque findings makes its detection easier and hence chest radiograph continues to be a suitable tool for screening asbestos-related pleural plaques based on its simplicity, low radiation exposure, wide availability and cost-effectiveness(23).

Other in the review of results of the published studies concerning radiography or CT note that the great interobserver variability in the recognition of pleural plaques and asbestosis, indicating the need for adequate training of radiologists, and the importance of defining standardized, quantified criteria for CT abnormalities. The very low agreement between thoracic and general radiologists must be taken into account. The reading of CT scans in cases of occupational exposure to asbestos should be entrusted to thoracic radiologists or to general radiologists having validated specific training. A double interpretation of CT could be considered in medicosocial requests. CT is more sensitive than chest radiography in the detection of bronchial carcinoma but generates a great number of false positive results (96 to 99%)(24).

2. MRI
In the study to compare respiratory-gated high-spatial resolution magnetic resonance imaging (MRI) and radial MRI with ultra-short echo times with computed tomography (CT) in the diagnosis of asbestos-related pleural disease, by the German Cancer Research Center, indicated that high-resolution MR sequences and radial MRI achieve a comparable interobserver agreement in detecting pleural plaques and even a higher interobserver agreement in assessing pleural thickening, pleural effusion, and extrapleural fat when compared with CT(25).

All Forms of Arthritis are Curable
You Can Eliminate Osteoarthritis
By addressing the Underlying Causes through Clinical Trials and Studies

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months


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Thursday, March 31, 2016

The Best Smoothie of Celery, Apple and Green tea for prevention and treatment of Hypertension nephrosclerosis

Kyle J. Norton(Scholar, Master of Nutrients), all right reserved.
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

The smoothie for reduced risk of Hypertensive nephrosclerosis

Yield: 2 servings (about 8 ounces each)
3/4 cup celery
3/4 cup of apple with peel
1 cup green tea drink 1 cup green tea drink (Make from 4 grams(2 tea bags) of green tea, a slice of ginger and a cup of hot water lipped for 5 minutes, and set aside for cooling to room temperature)

1. Place the celery, apple with peels, green tea, in a blender and puree about 1 minute
2. Blend on high speed about 1 minute or until the mixture is thick and the ice is well crushed.
3. Serve immediately

Blood pressure is the force of blood pushing against the walls of the arteries as the heart pumps out blood. high blood pressure means raising pressure in your heart. If your blood pressure stays high over time it can damage the body in many ways.
Blood pressure medications have undoubtedly prevented many deaths from heart disease in the past 30 years, but also induced many irreversible adverse effects, including kidney damage.

Hypertensive nephrosclerosis is a kidney disease without causing severe damage to the kidney, in association with long-standing hypertension. The risk of hypertension  induced serious renal damage is low in diabetic patients.

Diet rich in fruits and vegetable and reduced intake of red meat, saturated fat and trans fat has shown to attenuated risk of hypertension(1). Recent study showed that celery(2) intake used conjunction with berries(3) and green tea(4) may be the potential drink for prevention and treatment of hypertension.

Celery is a species of Apium graveolens, belongings to the family Apiaceae, cultivated all around the globe as a vegetable. According to Chronic administration of hexanic, methanolic, and aqueous-ethanolic extracts of celery seed effectively exhibited an antihypertensive activity in chronic treatment of elevated BP in tested animals(5).
Dr. Dianat M and the research team at the Ahvaz Jundishapur University of Medical Sciences said," hydro-alcoholic celery leaf extract on systolic blood pressure (SBP), heart rate (HR) and lipid profile in animals' model of hypertension induced by fructose"(6)
3‑n‑butylphthalide (NBP), an phytochemical found in celery seed used in traditional Chinese medicine exhibited significantly antihypertensive and attenuated progression of hypertensive effects through decreased oxidative stress and the expression of pro‑inflammatory cytokines(7). 

Apple is the pomaceous fruit of the apple tree, a species of the rose family Rosaceae. It is one of the most widely cultivated tree fruits. With phytochemical flavonoids, apple and its peel inhibited angiotensin converting enzyme (ACE) in promoted the development of high blood pressure, Dr Balasuriya N and Dr. Rupasinghe HP. Suggested(8)According to the Mount Sinai School of Medicine, "Flavonoid (found abundantly in fruits and vegetable)(10) intake has been inversely associated with mortality from coronary heart disease and stroke,..... Lowering blood pressure through increased dietary consumption of dietary antioxidants(such as flavonoid) may decrease the rate of end-organ damage that is secondary to hypertension"(9).

Green tea has been a precious drink in traditional Chinese culture and used exceptional in socialization for more than 4000 thousand years. Due to its commercial values and health effects, green tea now has been cultivated all over the world in suitable climate.

Epigallocatechin-3-O-gallate (EGCG), the main polyphenol presence in green tea is best known for its antioxidant and anti inflammatory effect. In animal model, the phytochemical exhibited anti hypertensive and progressive activity through reduction of oxidative stress in paraventricular nucleus of hypothalamus (PVN), the Xi'an Jiaotong University Health Science Center study showed(11).

Dr. Yarmolinsky J and the research team at the Federal University of Rio Grande do Sul, suggested that, intake of tea are shown to reduce blood pressure in individuals within prehypertensive and hypertensive ranges in the review of all relevant studies published from 1946 to September 27, 2013.(12).

Furthermore, green tea extract (GTE) inhibited the oxidative stress and ingiotensin (Ang) II induces endothelial dysfunction (ED) causes of hypertension through scavenging of superoxide anion generation, the University of Padova, insisted(13).

People who are at increased risk of hypertension due to family history .....should drink at least one cup daily and people with chronic hypertension should drink the juices at least 3 times a day, depending to digestive toleration.
Change of life style and diet pattern are also recommended.

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You Can Eliminate Osteoarthritis
By addressing the Underlying Causes through Clinical Trials and Studies

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

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References
(1) Fruit and Vegetable Consumption and the Incidence of Hypertension in Three Prospective Cohort Studies by Borgi L1, Muraki I2, Satija A2, Willett WC2, Rimm EB2, Forman JP2.(PubMed)
(2) The effect of hydro-alcoholic celery (Apiumgraveolens) leaf extract on cardiovascular parameters and lipid profile in animal model of hypertension induced by fructose by Dianat M1, Veisi A1, Ahangarpour A1, Fathi Moghaddam H1.(PubMed)
(3) Flavonoids from fruit and vegetables: a focus on cardiovascular risk factors by Toh JY1, Tan VM, Lim PC, Lim ST, Chong MF.(PubMed)
(4) Decaffeinated green tea extract improves hypertension and insulin resistance in a rat model of metabolic syndrome by Ihm SH1, Jang SW, Kim OR, Chang K, Oak MH, Lee JO, Lim DY, Kim JH.(PubMed)
(5) Antihypertensive effect of celery seed on rat blood pressure in chronic administration by Moghadam MH1, Imenshahidi M, Mohajeri SA.(PubMed)
(6) The effect of hydro-alcoholic celery (Apiumgraveolens) leaf extract on cardiovascular parameters and lipid profile in animal model of hypertension induced by fructose by Dianat M1, Veisi A1, Ahangarpour A1, Fathi Moghaddam H1.(PubMed)
(7) Protective effect of 3-n-butylphthalide against hypertensive nephropathy in spontaneously hypertensive rats by Zhu J1, Zhang Y1, Yang C1.(PubMed)
(8) Antihypertensive properties of flavonoid-rich apple peel extract by Balasuriya N1, Rupasinghe HP.(PubMed)
(9) Dietary flavonoids and hypertension: is there a link? by Moline J1, Bukharovich IF, Wolff MS, Phillips R.(PubMed)
(10) Antihypertensive effects of the flavonoid quercetin by Perez-Vizcaino F1, Duarte J, Jimenez R, Santos-Buelga C, Osuna A.(PubMed)
(11) Paraventricular Nucleus Infusion of Epigallocatechin-3-O-Gallate Improves Renovascular Hypertension by Yi QY1, Qi J, Yu XJ, Li HB, Zhang Y, Su Q, Shi T, Zhang DM, Guo J, Feng ZP, Wang ML, Zhu GQ, Liu JJ, Shi XL, Kang YM.(PubMed)
(12) Effect of tea on blood pressure for secondary prevention of cardiovascular disease: a systematic review and meta-analysis of randomized controlled trials by Yarmolinsky J1, Gon G2, Edwards P2.(PubMed)
(13) Prevention of hypertension, cardiovascular damage and endothelial dysfunction with green tea extracts by Antonello M1, Montemurro D, Bolognesi M, Di Pascoli M, Piva A, Grego F, Sticchi D, Giuliani L, Garbisa S, Rossi GP.(PubMed)

Most Common Diseases of elder: Respiratory Pleural disease: Pleural Plaques - Diseases associated to Asbestos exposure

Kyle J. Norton(Scholar and Master of Nutrients, all right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

                                          Respiratory Disease

Respiratory Disease is defined as medical conditions, affecting the breathing organ and tissues including Inflammatory lung disease, Obstructive lung diseases, Restrictive lung diseases, Respiratory tract infections, trachea, bronchi, bronchioles, alveoli, the nerves and muscles breathing, etc,.

                   Pleural disease: Pleural Plaques

The pleura is a thin tissue covered by a layer of cells (mesothelial cells) that surrounds the lungs and lines the inside of the chest wall.
Pleural plaques is a medical condition as a result of exposure to asbestos that lead to accumulated plagues within the pleural cavity(a). Many diseases such as pneumonia, breast cancer, and heart failure can affect the pleural space.,therefore, it is often a secondary effect of another disease process.

                                                   Misdiagnosis


According to Nigel Askew from the article factory, there are five main asbestos diseases including asbestos cancer that can develop following exposure to asbestos fibres: malignant asbestos mesothelioma cancer, asbestos lung cancer, asbestosis, asbestos pleural thickening and asbestos pleural plaques, however, doctors who do not regularly diagnose asbestos disease can misdiagnose (or be slow to give a diagnosis) what the condition is. This can lead to sufferers of asbestos disease wrongly concluding they do not have a right to make an asbestos claim(20).

1. Pleural mesothelioma
In the study designed to examine the association between pleural plaques on computed tomography (CT) scan and the risk of pleural mesothelioma in a follow-up study of asbestos-exposed workers, indicated that a total of 17 incident cases of pleural mesothelioma were diagnosed. A statistically significant association was observed between mesothelioma and pleural plaques (unadjusted hazard ratio (HR) = 8.9, 95% confidence interval [CI] = 3.0 to 26.5; adjusted HR = 6.8, 95% CI = 2.2 to 21.4 after adjustment for time since first exposure and cumulative exposure index to asbestos)(19).

2. Asbestos-related pleural abnormalities
In the study to study the observer agreement in several asbestos-related pleural abnormalities and to define criteria to discriminate between pleural changes in workers with occupational disease, and those in controls, found that the extent, calcification and thickness were well-repeatable indicators of benign pleural pathology and thus their use in future classification systems in computed tomography is recommended. In our material, the extent of 45 cm(2) and the degree of calcification were helpful in discriminating between pleural changes in workers with occupational disease, and those in controls who also presented marked pleural pathology(21).

3. Parietal pleural plaques
According to the study lead by Svenes KB, in a series of 402 consecutive autopsies, parietal pleural plaques (PP) were found in 68 individuals above 40 years of age. The frequency of PP was 26.9% in males and 3.1% in females. In 28 cases chest roentgenographs taken shortly before death were available. These films were randomly mixed with chest roentgenographs from 33 subjects who had subsequently died and in whom no PP had been found at autopsy. All films were scrutinized by two experienced readers, ignorant of the case histories and autopsy findings. In less than half the PP cases was this diagnosis suggested from the roentgenological examination. On the other hand, the readers had 13 and 14 cases with positive or uncertain findings in the 33 cases with no PP found at autopsy(22)



All Forms of Arthritis are Curable
You Can Eliminate Osteoarthritis
By addressing the Underlying Causes through Clinical Trials and Studies

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Super foods Library, Eat Yourself Healthy With The Best of the Best Nature Has to Offer