Wednesday, April 6, 2016

Most Common Disease of 50Plus: The Clinical trials and Studies of Musculo-Skeletal disorders(MSDs) - Osteoarthritis: The Antioxidants

Kyle J. Norton (Scholar)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

Musculoskeletal disorders (MSDs) are medical condition mostly caused by work related occupations and working environment, affecting patients’ muscles, joints, tendons, ligaments and nerves and developing over time. A community sample of 73 females and 32 males aged 85 and over underwent a standardised examination at home. Musculoskeletal pain was reported by 57% of those interviewed. A major restriction of joint movement range was frequent in the shoulder but uncommon in other joints(1).

Types of Musculo-Skeletal disorders in elder(2)

1. Osteoarthritis
2. Gout
3. Rheumatoid Arthritis
4. Polymalagia Arthritis
5. Cervical myleopathy and spinal canal stenosis
6. Osteoporosis
7. Low back pain
8. Fibromyalgia      



                                                      Osteoarthritis


Osteoarthritis (OA), a form of arthritis, is defined as a condition of as a result of aging causes of wear and tear on a joint, affecting over 25 million people in the United States in alone. University of Porto Medical School indicated that one must understand the differences in prevalence and incidence estimates of osteoarthritis (OA), according to case definition, in knee, hip and hand joints(3).
The characteristics of osteoarthritis are aching pain(5), stiffness(6), or difficulty of moving the joint or joints(7). The pain usually gets worse in change of weather, at night and in the advanced diseases, the pain can occur even at rest(8). Today management of osteoarthritis (OA) focuses on pain relief and improved physical function through pharmacological, non pharmacological, and surgical treatments(4).

               The Preventive and Management Antioxidants


1. Immune system and functioning (Free radical scavengers)
Free Radicals play an important role in the function of the Immune System. The immune system produces free radicals to kill foreign microbes(176)(177), but the production of free radical sometime can be excessive, leading to formation of a large number of free radicals(178)(179). The domino effects have shown to induce many chronic illness, such as cancers(179)
a. Vitamin A
vitamin A plays an essential roles in enhancing a broad range of immune processes, including white blood cells activation and proliferation(180)(181)of T-helper-cell differentiation, the production of specific antibody in regulation of the immune response(182).
b. Vitamin C
Researchers found that vitamin C raised the concentration in the blood of total immunoglobulin(183) in promotion of the ability of antibodies and phagocytic cells to clear pathogens(184).
c. Vitamin E
Vitamin E not only increased both cell-dividing and IL-producing capacities of naive T cells(185) but also enhanced the immune functions(186) in association with significant improvement in resistance to influenza infection(187).
d. Zinc
Zinc, having a regulatory role in the immune system,(189) as a antioxidant is essential mineral improved immune system by enhancing the proper function of T and B cells(188) which belong to a group of white blood cells known as lymphocytes, in fighting against damaging free radicals(190).

2. Antioxidants and osteoarthritis
Diet included vitamin E significantly reduce the levels of inflammation by analyzing the pro and anti-inflammatory cytokines in the blood serum(193). According to the study of "Antioxidants and antiinflammatory dietary supplements for osteoarthritis and rheumatoid arthritis", vitamins A, C, and E in combination; ginger; turmeric; or Zyflamend (New Chapter, Brattleboro, Vermont) have found to be effective for the treatment of OA(191). According to Dr. Christensen R, and DR. Bliddal H. food supplement containing fish oils, urtica dioica, zinc, and vitamin E (Phytalgic) may also have a very large clinical effect, for treatment of OA(192)

b. Glucosamine
Glucosamine, a compound of the simple sugar glucose and the amino acid glutamine, is a precursor for glycosaminoglycans(194), a major component of joint cartilage(195). Treatment of glucosamine sulfate, chondroitin sulfate, hyaluronic acid, collagen hydrolysate, or nutrients, such as antioxidants and omega-3 fatty acids showed to prevent cartilage degeneration and treat arthritis, according to study(195).

c. DLPA (dl- phenylalanine)
DLPA, a mixture of D-Phenylalanine and L-Phenylalanine, is a nutritional supplement amino acid(196). showed effectively in treatment for OA (197) as well as reducing arthritis pain(198) and joint inflammation(198) in many patients.

d. Methylsulfonylmethane, also known DMSO2 is an organosulfur compound with the formula (CH3)2SO2
In a randomized, double-blind, placebo-controlled trial of Fifty men and women, 40-76 years of age with knee OA pain enrolled in an outpatient medical center. MSM (3g twice a day) improved symptoms of pain and physical function during the short intervention without major adverse events, after 12 weeks(199)(200)


3. Etc.

Arthritis Is Curable
You Can Eliminate Osteoarthritis
By addressing the Underlying Causes through Clinical Trials and Studies


Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months


Back to General health http://kylejnorton.blogspot.ca/


Back to Kyle J. Norton Home page http://kylejnorton.blogspot.ca p/general-health.html


Super foods Library, Eat Yourself Healthy With The Best of the Best Nature Has to Offer


References
(1) Prevalence of rheumatic symptoms, rheumatoid arthritis, ankylosing spondylitis, and gout in Shanghai, China: a COPCORD study by Dai SM1, Han XH, Zhao DB, Shi YQ, Liu Y, Meng JM.(PubMed)
(2) Musculoskeletal Disorders in the Elderly by Ramon Gheno, Juan M. Cepparo, Cristina E. Rosca,1 and Anne Cotten(PMC)
(3) The effect of osteoarthritis definition on prevalence and incidence estimates: a systematic review by Pereira D1, Peleteiro B, Araújo J, Branco J, Santos RA, Ramos E.(PubMed)
(4) Effect of therapeutic aquatic exercise on symptoms and function associated with lower limb osteoarthritis: systematic review with meta-analysis by Waller B1, Ogonowska-Slodownik A2, Vitor M3, Lambeck J4, Daly D5, Kujala UM6, Heinonen A7.(PubMed)
(5) Effects of therapeutic ultrasound on pain, physical functions and safety outcomes in patients with kneeosteoarthritis: A systematic review and meta-analysis by Zhang C1, Xie Y2, Luo X3, Ji Q3, Lu C3, He C4, Wang P3.(PubMed)
(6) Oral intake of purple passion fruit peel extract reduces pain and stiffness and improves physical function in adult patients with knee osteoarthritis by Farid R1, Rezaieyazdi Z, Mirfeizi Z, Hatef MR, Mirheidari M, Mansouri H, Esmaelli H, Bentley G, Lu Y, Foo Y, Watson RR.(PubMed)
(7) Functional ability, mobility, and pain before and after knee replacement in patients aged 75 and older: a cross-sectional study by Limnell K1, Jämsen E, Huhtala H, Jäntti P, Puolakka T, Jylhä M.(PubMed)

(176) Free Radicals, Antioxidants in Disease and Health by Lien Ai Pham-Huy,1 Hua He,2 and Chuong Pham-Huy3(PMC)
(177) Superoxide Anion and Its Functions(Beta Forces)
(178) Free radicals and antioxidants in normal physiological functions and human disease by Valko M1, Leibfritz D, Moncol J, Cronin MT, Mazur M, Telser J.(PubMed)
(179) Free radicals, metals and antioxidants in oxidative stress-induced cancer by Valko M1, Rhodes CJ, Moncol J, Izakovic M, Mazur M.(PubMed)
(180) Vitamin A, immunity, and infection by Semba RD1.(PubMed)
(181) Vitamin A as an immunomodulating agent by Rumore MM1.(PubMed)
(182) The effect of newborn vitamin A supplementation on infant immune functions: trial design, interventions, and baseline data by Ahmad SM1, Raqib R2, Qadri F3, Stephensen CB4(PubMed)
(183) Effect of dietary vitamin C on the growth performance and innate immunity of juvenile cobia (Rachycentron canadum) by Zhou Q1, Wang L, Wang H, Xie F, Wang T.(PubMed)
(184) The treatment of poliomyelitis and other virus diseases with vitamin C by KLENNER FR.(PubMed)
(185) Vitamin E-enhanced IL-2 production in old mice: naive but not memory T cells show increased cell division cycling and IL-2-producing capacity by Adolfsson O1, Huber BT, Meydani SN.(PubMed)
(186) Vitamin E and immune response in the aged: molecular mechanisms and clinical implications. by Meydani SN1, Han SN, Wu D.(PubMed)
(187) Vitamin E and infectious diseases in the aged by Han SN1, Meydani SN.(PubMed)
(188) Zinc and its role in immunity and inflammation by Bonaventura P1, Benedetti G1, Albarède F2, Miossec P3.(PubMed)
(189) Zinc homeostasis and immunosenescence by Maywald M1, Rink L2.(PubMed)
(190) Dietary zinc deficiency induced-changes in the activity of enzymes and the levels of free radicals, lipids and protein electrophoretic behavior in growing rats by Yousef MI1, El-Hendy HA, El-Demerdash FM, Elagamy EI.(PubMed)
(191) Antioxidants and antiinflammatory dietary supplements for osteoarthritis and rheumatoid arthritis by Rosenbaum CC1, O'Mathúna DP, Chavez M, Shields K.(PubMed)
(192) Is Phytalgic(R) a goldmine for osteoarthritis patients or is there something fishy about this nutraceutical? A summary of findings and risk-of-bias assessment by Christensen R, Bliddal H.(PubMed)
(193) Vitamin E has a dual effect of anti-inflammatory and antioxidant activities in acetic acid–induced ulcerative colitis in rat by Gulgun Tahan, MD,*† Erman Aytac, MD,* Huseyin Aytekin, MD,‡ Feyza Gunduz, MD,† Gulen Dogusoy, MD,§ Seval Aydin, MD,¶ Veysel Tahan, MD,** and Hafize Uzun, MD(PMC)
(194) Glucosamine inhibits the synthesis of glycosaminoglycan chains on vascular smooth muscle cell proteoglycans by depletion of ATP by Little PJ1, Drennon KD, Tannock LR.(PubMed)
(195) Effects of Glucosamine and Chondroitin Sulfate on Cartilage Metabolism in OA: Outlook on Other Nutrient Partners Especially Omega-3 Fatty Acid by Jörg Jerosch(PubMed)
(196) NON-PHYSIOLOGICAL AMINO ACID (NPAA) THERAPY TARGETING BRAIN PHENYLALANINE REDUCTION: PILOT STUDIES IN PAHENU2 MIC by Kara R. Vogel,1 Erland Arning,2 Brandi L. Wasek,2 Teodoro Bottiglieri,2 and K. Michael Gibson1,(PubMed)
(197) DLPA (D, L Phenylalanine)(Whole health Chicago)
(198) PHENYLALANINE(WebMD)
(199) Efficacy of methylsulfonylmethane (MSM) in osteoarthritis pain of the knee: a pilot clinical trial. by Kim LS1, Axelrod LJ, Howard P, Buratovich N, Waters RF.(PubMed)
(200) Efficacy of methylsulfonylmethane supplementation on osteoarthritis of the knee: a randomized controlled study by Debbi EM1, Agar G, Fichman G, Ziv YB, Kardosh R, Halperin N, Elbaz A, Beer Y, Debi R.(PubMed)

The Best of Sweet Potato, Tomato and Orange Juice for Prevention and Treatment of Adenosis, a benign breast disease

Kyle J. Norton(Scholar, Master of Nutrients), all right reserved.
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

The smoothie for reduced risk and Treatment of  Adenosis, a benign breast disease
Yield: 2 serving (about 8 ounce each)
1/8 cup cooked sweet potato
1/4 cup tomato
1 4/5 cups orange juice

1. Place all ingredients in a blender and puree about 1 minute
2. Blend on high speed about 1 minute or until the mixture is thick and the ice is well crushed. Add more green tea drink if needed
3. Serve immediately

The finding the natural ingredients for treatment of Adenosis is considered as a dream of many scientist to replace the long term usage adverse effect of conventional medicine to other organs in the body. Unfortunately, many compounds found effective in initial studying failed to confirm the potential in large sample size and multi center.

Adenosis tumor is a benign breast disorder of enlarged breast lobules, containing more glands than usual. Although  Adenosis tumor is not a precursor of breast cancer, women with adenosis tumor are at increased risk of developed invasive breast cancer(1).

Women with benign breast disease(BBD) are found to have lower antioxidant status, probably to compensate for this elevated free radical production(3)

According to the, dietary supplement "Karinat" containing beta-carotene 2.5 mg, alpha-tocopherol 5 mg, ascorbic acid 30 mg and garlic powder 150 mg per one tablet in a total of 66 patients twice a day during 6 months exhibited anti benign breast disease up to 75.8% in comparison to placebo(2).

According to the Chinese University of Hong Kong, Intakes of vitamin E and individual carotenoids may associate to reduce risk proliferative BBD(4), particular in carotenoids intake in BBD of adolescent girls(5).

Dr. Ramaswamy G and Dr. Krishnamoorthy L. said, "Serum ascorbate levels were significantly lower in patients with benign diseases of the breast and cervix than in controls"(6).


The effectiveness of Sweet Potato(Vitamin E), Tomato(Vitamin A) and Orange Juice(Ascorbic Acid or Vitamin C )  may serve as cornerstones of pharmaceutical target for further studies in production of a potential medication for for Reduced Risk and treatment of Adenosis, a benign disease of the breast with little or no adverse effects.

Women who are at increased risk of Adenosismay drink at least one serving daily and women with Adenosis may drink as much as they can, depending to the digestive toleration.
Life style and dietary patter change are recommended

All Forms of Arthritis are Curable
You Can Eliminate Osteoarthritis
By addressing the Underlying Causes through Clinical Trials and Studies

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to General health http://kylejnorton.blogspot.ca/p/general-health.html

Back to Kyle J. Norton Home page http://kylejnorton.blogspot.ca


References
(1) Benign breast disease and the risk of breast cancer in the next 15 years by Socolov D, Anghelache I, Ilea C, Socolov R, Carauleanu A.(PubMed)
(2) [Study of an antioxidant dietary supplement "Karinat" in patients with benign breast disease].
[Article in Russian] by Bespalov VG, Barash NIu, Ivanova OA, Krzhivitskiĭ PI, Semiglazov VF, Aleksandrov VA, Sobenin NA, Orekhov AN.(PubMed)
(3) Lipid peroxidation and antioxidant status in blood and tissue of malignant breast tumor and benign breast disease by Gönenç A1, Erten D, Aslan S, Akinci M, Simşek B, Torun M.(PubMed)
(4) Intakes of fat and micronutrients between ages 13 and 18 years and the incidence of proliferative benign breast disease. by Su X1, Boeke CE, Collins LC, Baer HJ, Willett WC, Schnitt SJ, Connolly JL, Rosner B, Colditz GA, Tamimi RM.(PubMed)
(5) Adolescent carotenoid intake and benign breast disease by Boeke CE1, Tamimi RM2, Berkey CS3, Colditz GA4, Eliassen AH2, Malspeis S5, Willett WC6, Frazier AL7.(PubMed)
(6) Serum carotene, vitamin A, and vitamin C levels in breast cancer and cancer of the uterine cervix. by Ramaswamy G1, Krishnamoorthy L.(PubMed)

Most Common Diseases of 50plus: Pulmonary vascular disease(Respiratory disease): Pulmonary edema- Signs and Symptoms

Kyle J. Norton(Scholar and Master of Nutrients, all right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

                           Respiratory Disease

Respiratory Disease is defined as medical conditions, affecting the breathing organ and tissues including Inflammatory lung disease, Obstructive lung diseases, Restrictive lung diseases, Respiratory tract infections, trachea, bronchi, bronchioles, alveoli, the nerves and muscles breathing, etc,.

         Pulmonary vascular disease:  Pulmonary edema


Pulmonary vascular disease is defined as a condition of blood flow to the lung’s artery is blocked suddenly due to a blood clot somewhere in the body, including pulmonary embolism, chronic thromboembolic disease, pulmonary arterial hypertension, pulmonary veno-occlusive disease, pulmonary arteriovenous malformations, pulmonary edema, etc.
                                                    
Pulmonary edema is defined as a condition of fluid accumulation in the air spaces and parenchyma of the lungs of that can lead to difficult of breathing and respiratory failure.

                                                          Signs and Symptoms

Acute pulmonary edema can be classified as either cardiogenic or noncardiogenic or both. Cardiogenic pulmonary edema occurs when the pulmonary capillary hydrostatic pressure exceeds plasma oncotic pressure. Noncardiogenic pulmonary edema occurs when pulmonary capillary permeability is increased(a).
1. Shortness of breath, precipitation, high systolic blood pressure, and chest pain
In the study to
1) describe the prehospital clinical presentation and management of patients with a clinical diagnosis of APE and
2) compare the accuracy of coding of APE by paramedics against the emergency department (ED) medical discharge diagnosis, including a retrospective cohort of all patients who had episodes identified as APE by ambulance paramedics and were transported to a metropolitan hospital ED in 2011, found that four hundred ninety-five patients were transported to an ED with APE identified by the paramedics as the primary problem code. Shortness of breath, crepitations, high systolic blood pressure, and chest pain were the most common presenting signs and symptoms. Pink frothy sputum was rare (3% of patient episodes of APE)(1). 

2. Severe respiratory distress with evident inability to adequately ventilate and/or oxygenate
According to the study by the University Hospital of Pisa there is a series of study with the use of intravenous atenolol, a short-acting cardioselective beta-adrenergic antagonist, to treat acute pulmonary edema in the prehospital setting. Four patients with a documented history of cardiac disease and one patient with unknown cardiac issues experienced severe respiratory distress and presented with pulmonary edema; the local emergency medical service was utilized. In all of the patients, the saturation of peripheral oxygen (SpO2) was severely low, and the patients were rapidly treated with oxygen, diuretics, morphine, and nitrates(2).

3. According to the article by Jack Hirsh, MD; John Hoak, MD, patients who survive an acute PE are at high risk for recurrent PE and for the development of pulmonary hypertension and chronic cor pulmonale, which occurs in up to 70% of patients and carries its own attendant mortality and morbidity. Massive PE causes hypotension due to acute cor pulmonale, but the physical examination findings early in submassive PE may be completely normal. Initially, abnormal physical findings are absent in most patients with PE. After 24-72 hours, loss of pulmonary surfactant often causes atelectasis and alveolar infiltrates that are indistinguishable from pneumonia on clinical examination and by x-ray. New wheezing may be appreciated. If pleural lung surfaces are affected, a pulmonary rub may be heard.

The spontaneous onset of chest wall tenderness without a good history of trauma is always worrisome, because patients with PE may have chest wall tenderness as the only physical finding.
In patients with massive PE, the incidence of physical signs has been reported as follows:
96% have tachypnea (respiratory rate >16/min)
58% develop rales 53% have an accentuated second heart sound 44% have tachycardia (heart rate >100/min)
43% have fever (temperature >37.8° C)
36% have diaphoresis
34% have an S3 or S4 gallop
32% have clinical signs and symptoms suggesting thrombophlebitis
24% have lower extremity edema
23% have a cardiac murmur
19% have cyanosis (3)

All Forms of Arthritis are Curable
You Can Eliminate Osteoarthritis
By addressing the Underlying Causes through Clinical Trials and Studies

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Super foods Library, Eat Yourself Healthy With The Best of the Best Nature Has to Offer

Tuesday, April 5, 2016

Most Common Disease of 50Plus: The Clinical trials and Studies of Musculo-Skeletal disorders(MSDs) - Osteoarthritis: The Diet

Kyle J. Norton (Scholar)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

Musculoskeletal disorders (MSDs) are medical condition mostly caused by work related occupations and working environment, affecting patients’ muscles, joints, tendons, ligaments and nerves and developing over time. A community sample of 73 females and 32 males aged 85 and over underwent a standardised examination at home. Musculoskeletal pain was reported by 57% of those interviewed. A major restriction of joint movement range was frequent in the shoulder but uncommon in other joints(1).

Types of Musculo-Skeletal disorders in elder(2)

1. Osteoarthritis
2. Gout
3. Rheumatoid Arthritis
4. Polymalagia Arthritis
5. Cervical myleopathy and spinal canal stenosis
6. Osteoporosis
7. Low back pain
8. Fibromyalgia        



                                                      Osteoarthritis


Osteoarthritis (OA), a form of arthritis, is defined as a condition of as a result of aging causes of wear and tear on a joint, affecting over 25 million people in the United States in alone. University of Porto Medical School indicated that one must understand the differences in prevalence and incidence estimates of osteoarthritis (OA), according to case definition, in knee, hip and hand joints(3).
The characteristics of osteoarthritis are aching pain(5), stiffness(6), or difficulty of moving the joint or joints(7). The pain usually gets worse in change of weather, at night and in the advanced diseases, the pain can occur even at rest(8). Today management of osteoarthritis (OA) focuses on pain relief and improved physical function through pharmacological, non pharmacological, and surgical treatments(4).

                      The Prevention and management Diet


The aims of the diet is to provide protection to avoid elevation of the inflammatory effects(139) in induced-degeneration causes of osteoarthritis(133)(134)
1. Green tea
Epigallocatechin 3-gallate (EGCG), according to the College of Pharmacy, found abundantly in green tea showed to exhibit its anti anti-rheumatic activity in patients with joint diseases(140) through its antioxidant property(141).

2. Salmon
Salmon is the common name for Salmonidae, born in fresh water, migrate to the ocean, then travel thousands of miles in the deep sea cold water throughout their life cycle and within five years returning to the exacted location where they were born to reproduce and die.
a. Weight loss
Intake of salmon oil has shown to induce body weight loss in mice, according to the study by University of Washington(142). N3 long-chain polyunsaturated fatty acids (n3-LCPUFA) enhanced body weight loss, at the end of the 1-month period in 16 children through deduction of insulin resistance(143).


b. Antioxidants
Megadoses of vitamin E, found in salmon oil exhibited pro-oxidative activity, through increased the anti-oxidative capacity of the liver(144).

c. Omega 3 fatty acids
Omega 3 fatty acids is necessary to maintain the ratio of good and bad cholesterol(145), thus reducing the risk of cholesterol inflammation(146)(148) cause of heart diseases (147) and osteoarthritis(133)(134).

d. Anti inflammation
Omega 3 fatty acids not only reduces the risk of inflammatory effects on our joints and improved blood flow(149), by regulating the migration of inflammatory cells(139), but also reduce the elevation of the proinflammatory leukotriene LTB(4) causes of autoimmune diseases(150).

3. Walnut tree
Walnut tree, cultivated for its nut and kernel and for commercial purpose all over the world, is one of the Genus plant belong to the family Juglandaceae about 30–130 ft).
a. Antioxidant effects(151)(152)
Even-though walnuts consumption did not only significantly change the plasma antioxidant capacity of healthy, well-nourished older adults through its polyphenols in inhibitiobn plasma and LDL oxidation(151) but chronic consumption, it improved postprandial serum antioxidants and biomarkers of oxidative status(152) through its antioxidant linoleic acid and pyridoxal phosphate in enhancing total plasma thiols(151).


b. Inflammation defense(153)
Intake of walnuts is shown to promote manganese superoxide dismutase (MnSOD), an enzyme located in mitochondria(154), is the key enzyme in protection of the energy-generating mitochondria from oxidative damage caused by free radicals(155).

c. Diabetes risk

Adiponectin found abundantly in walnut-enriched meal plays an important causal role in insulin resistance and metabolic syndrome(156). Diabetes in older adult is shown to associate increased risk of osteoarthritis(157).



4. Dulse
Dulse, commonly used in Ireland and Atlantic Canada both as foods and medicines, is a red seaweed of genus Palmaria, belong to Family Palmariaceae grown attached to rocks by a “holdfast” in the North Atlantic and Northwest Pacific. Dulse is found in many health food stores or fish markets or can be ordered directly from local distributors.
a. Health benefits
Seaweeds, including dulse, showed to consist a important functional activities, such as antioxidant(158)(160)(161), antimutagenic(159)(162) and anticoagulant effect(160), antitumor activity(160), and modification of lipid metabolism(161).
b. Antioxidants
Dulse extracts showed to inhibit certain lipid peroxidations(162).
c. Weigh loss
As a rich source of fiber, dulse enhances the process of digestion, for making the stomach feeling fullness, thus reducing the risk of insulin cause of food craving(163).

5. Lime (Lemon)
Lime, a around shape with green to yellow in color and 3–6 cm in diameter, is a species of Citrus Aurantifolia, belongs to the family Rutaceae, native to Southeast Asia.
a. Antioxidant
Lime flower extract may contain high levels of antioxidant(164)(165) but lesser than the ethanol extract of cinnamon(166).
b. Vitamin C
Besides preventing the breaking off small vein cause of hardening of the vessel wall(167), vitamin C also improves the digestive system in maximum absorption of vital nutrients and plays an important role in enhancing immune system fighting against the forming of free radicals that cause muscle damage(168). According to the University of Limerick, prior supplementation with dietary antioxidants, such as vitamin C and E may ameliorate muscle functional decrements subsequent to eccentric muscle contraction(169).

6. Dairy Products
Dairy products contain high amount of nutrients, it also has measure amount of vitamin D of which is necessary for the body in calcium absorption(170). Intake of dairy products per day, according to joint study including Université Libre de Bruxelles appears to be safe and may confer a favourable benefit with regard to bone health, such as osteoarthritis(172), rheumatoid arthritis(170).
In elderly Fracture risk, according to the Geneva University Hospitals and Faculty of Medicine, improved bone growth is influenced by dietary intake, particularly of calcium and protein such as Dairy products, yogurts are essential to achieve optimal peak bone mass during skeletal growth and to prevent bone loss(171). Recommendation of consuming 3 servings of dairy products per day during childhood and adolescence, has shown to improve bone health and reduce the risk of fractures in later life(171).
In the observation of a significant dose-response relationship between baseline milk intake and adjusted mean decrease of JSW in women, researcher at the Brigham and Women's Hospital and Harvard Medical School, Boston, showed that frequent milk consumption may be associated with reduced OA progression in women and delay in knee OA progression(173).



Arthritis Is Curable
You Can Eliminate Osteoarthritis
By addressing the Underlying Causes through Clinical Trials and Studies

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months


Super foods Library, Eat Yourself Healthy With The Best of the Best Nature Has to Offer recommended by Kyle J. Norton

Back to Kyle J. Norton Home page http://kylejnorton.blogspot.ca


References
(1) Prevalence of rheumatic symptoms, rheumatoid arthritis, ankylosing spondylitis, and gout in Shanghai, China: a COPCORD study by Dai SM1, Han XH, Zhao DB, Shi YQ, Liu Y, Meng JM.(PubMed)
(2) Musculoskeletal Disorders in the Elderly by Ramon Gheno, Juan M. Cepparo, Cristina E. Rosca,1 and Anne Cotten(PMC)
(3) The effect of osteoarthritis definition on prevalence and incidence estimates: a systematic review by Pereira D1, Peleteiro B, Araújo J, Branco J, Santos RA, Ramos E.(PubMed)
(4) Effect of therapeutic aquatic exercise on symptoms and function associated with lower limb osteoarthritis: systematic review with meta-analysis by Waller B1, Ogonowska-Slodownik A2, Vitor M3, Lambeck J4, Daly D5, Kujala UM6, Heinonen A7.(PubMed)
(5) Effects of therapeutic ultrasound on pain, physical functions and safety outcomes in patients with kneeosteoarthritis: A systematic review and meta-analysis by Zhang C1, Xie Y2, Luo X3, Ji Q3, Lu C3, He C4, Wang P3.(PubMed)
(6) Oral intake of purple passion fruit peel extract reduces pain and stiffness and improves physical function in adult patients with knee osteoarthritis by Farid R1, Rezaieyazdi Z, Mirfeizi Z, Hatef MR, Mirheidari M, Mansouri H, Esmaelli H, Bentley G, Lu Y, Foo Y, Watson RR.(PubMed)
(7) Functional ability, mobility, and pain before and after knee replacement in patients aged 75 and older: a cross-sectional study by Limnell K1, Jämsen E, Huhtala H, Jäntti P, Puolakka T, Jylhä M.(PubMed)
(8) The symptoms of OA and the genesis of pain by David J. Hunter, MBBS PhD,1,2 Jason J. McDougall, BSc PhD,3 and Francis J. Keefe4(PubMed)

(141) Preparation and antioxidant activity of green tea extract enriched in epigallocatechin (EGC) and epigallocatechin gallate (EGCG) by Hu J1, Zhou D, Chen Y.(PubMed)
(142) Genetically determined body weight loss in mice fed diets containing salmon oil by LeBoeuf RC1, Veldee MS.(PubMed)
(143) Supplementation of n3 long-chain polyunsaturated fatty acid synergistically decreases insulin resistance withweight loss of obese prepubertal and pubertal children by López-Alarcón M1, Martínez-Coronado A, Velarde-Castro O, Rendón-Macías E, Fernández J.(PubMed)
(144) Effects of megadoses of dietary vitamin E on the antioxidant status of rats fed lard or salmon oil by Flader D1, Brandsch C, Hirche F, Eder K.(PubMed)
(145) Omega 3 fatty acids promote macrophage reverse cholesterol transport in hamster fed high fat diet by Kasbi Chadli F1, Nazih H, Krempf M, Nguyen P, Ouguerram K.(PubMed)
(146) Cholesterol, inflammation and innate immunity by Tall AR1, Yvan-Charvet L2.(PubMed)
(147) In vitro fatty acid enrichment of macrophages alters inflammatory response and net cholesterol accumulation by Wang S1, Wu D, Lamon-Fava S, Matthan NR, Honda KL, Lichtenstein AH.(PubMed)
(148) Uncoupling lipid metabolism from inflammation through fatty acid binding protein-dependent expression of UCP2. byXu H1, Hertzel AV1, Steen KA1, Wang Q2, Suttles J3, Bernlohr DA4.(PubMed)
(149) Low-dose aspirin and omega-3 fatty acids improve uterine artery blood flow velocity in women with recurrent miscarriage due to impaired uterine perfusion by Lazzarin N1, Vaquero E, Exacoustos C, Bertonotti E, Romanini ME, Arduini D.(PubMed)
(150) Omega-3 fatty acids in inflammation and autoimmune diseases. by Simopoulos AP1.(PubMed)
(151) Chronic and acute effects of walnuts on antioxidant capacity and nutritional status in humans: a randomized, cross-over pilot study by McKay DL1, Chen CY, Yeum KJ, Matthan NR, Lichtenstein AH, Blumberg JB.(PubMed)
(152) Effect of a walnut meal on postprandial oxidative stress and antioxidants in healthy individuals by Haddad EH1, Gaban-Chong N, Oda K, Sabaté J.(PubMed)
(153) Olive oil and walnut breakfasts reduce the postprandial inflammatory response in mononuclear cells compared with a butter breakfast in healthy men by Jiménez-Gómez Y1, López-Miranda J, Blanco-Colio LM, Marín C, Pérez-Martínez P, Ruano J, Paniagua JA, Rodríguez F, Egido J, Pérez-Jiménez F.(PubMed)
(154) manganese(The world healthier foods)
(155) The role of manganese superoxide dismutase in inflammation defense by Li C1, Zhou HM(PubMed)
(156) An acute intake of a walnut-enriched meal improves postprandial adiponectin response in healthy young adults by Lozano A1, Perez-Martinez P, Marin C, Tinahones FJ, Delgado-Lista J, Cruz-Teno C, Gomez-Luna P, Rodriguez-Cantalejo F, Perez-Jimenez F, Lopez-Miranda(PubMed)
(157) Links between osteoarthritis and diabetes: implications for management from a physical activity perspective by Piva SR1, Susko AM2, Khoja SS2, Josbeno DA2, Fitzgerald GK2, Toledo FG3.(PubMed)
(158) Antioxidant and cytotoxic activities of three species of tropical seaweeds by Chia YY1, Kanthimathi MS2,3, Khoo KS4, Rajarajeswaran J5, Cheng HM6, Yap WS7.(PubMed)
(159) Brown seaweed fucoidan: biological activity and apoptosis, growth signaling mechanism in cancer by Senthilkumar K1, Manivasagan P, Venkatesan J, Kim SK.(PubMed)
(160) Anticoagulant, Antioxidant and Antitumor Activities of Heterofucans from the Seaweed Dictyopteris delicatul by Kaline Dantas Magalhaes,1,2,† Leandro Silva Costa,1,3,† Gabriel Pereira Fidelis,1 Ruth Medeiros Oliveira,1 Leonardo Thiago Duarte Barreto Nobre,1 Nednaldo Dantas-Santos,1,2 Rafael Barros Gomes Camara,1 Ivan Rui Lopes Albuquerque,1,2 Sara Lima Cordeiro,1 Diego Araujo Sabry,1 Mariana Santana Santos Pereira Costa,1 Luciana Guimaraes Alves,1 and Hugo Alexandre Oliveira Rocha1,2(PMC)
(161) [Nutritional evaluation and physiological effects of edible seaweeds].[Article in Spanish] by Jiménez-Escrig A1, Goñi Cambrodón I.(PubMed)
(162) Extracts from dulse (Palmaria palmata) are effective antioxidants and inhibitors of cell proliferation in vitro by Yuan YV1, Carrington MF, Walsh NA.(PubMed)
(163) THE WORLD HEALTHIEST FOODS - PART II - VEGETABLES by Kyle J. Norton
(164) Role of bilirubin as antioxidant in neonatal jaundice and effect of ethanolic extract of sweet lime peel on experimentally induced jaundice in rat by Nag N1, Halder S, Chaudhuri R, Adhikary S, Mazumder S.(PubMed)
(165) Phytochemicals and antioxidant capacity of tortillas obtained after lime-cooking extrusion process of whole pigmented mexican maize by Aguayo-Rojas J1, Mora-Rochín S, Cuevas-Rodríguez EO, Serna-Saldivar SO, Gutierrez-Uribe JA, Reyes-Moreno C, Milán-Carril(PubMed)
(166) Antioxidant and anticholinesterase activities of eleven edible plants by Boğa M1, Hacıbekiroğlu I, Kolak U.(PubMed)
(167) Aging Hearts and Arteries: A Scientific Quest, Chapter 4: Blood Vessels and Aging: The Rest of the Journey(NIH)
(168) Does antioxidant vitamin supplementation protect against muscle damage? by McGinley C1, Shafat A, Donnelly AE(PubMed)
(169) Effects of dietary supplementation with vitamins C and E on muscle function during and after eccentric contractions in humans by Shafat A1, Butler P, Jensen RL, Donnelly AE.(PubMed)
(170) Effects of Dairy Products Consumption on Health: Benefits and Beliefs-A Commentary from the Belgian Bone Club and the European Society for Clinical and Economic Aspects of Osteoporosis, Osteoarthritis and Musculoskeletal Diseases by Rozenberg S1, Body JJ2, Bruyère O3, Bergmann P4, Brandi ML5, Cooper C6,7, Devogelaer JP8, Gielen E9, Goemaere S10, Kaufman JM11, Rizzoli R12,Reginster JY13(PubMed)
(171) Dairy products, yogurts, and bone health by Rizzoli R1.(PubMed)
(172) Got osteoarthritis? Maybe milk can help by Sahni S1, McLean RR.(PubMed)
(173) Milk consumption and progression of medial tibiofemoral knee osteoarthritis: data from the Osteoarthritis Initiative by Lu B1, Driban JB, Duryea J, McAlindon T, Lapane KL, Eaton CB(PubMed)

The Wonderful Smoothie of Cooked Sweet Potato and Mulberry Fruit Juices For Prevention and Treatment of Polyuria(Diuresis) in Kidney diseases

Kyle J. Norton (Scholar, and Master of nutrients) All right reserved
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years

Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

Imaging of long term intake of delicious smoothies loved by many with the power of reduced risk and treatment of chronic illness with no one mentions about. In fact, it happens. Epidemiological studies with strong evidences suggested that blueberry oral administration hold a potential with therapeutic values for reduced risk of women who carry the mutation gene and treatment of breast cancer(*).

The curable smoothies are collection of recipes produced from natural sources, including organic fruits and vegetables, and some herbs which have been proven effectively for reduced risk and treatment for diseases and syndromes by scientific research of clinical trials and/or studies.

The finding of foods from natural sources has been a dream of scientists and scholars since ancient time. Socrates Said," Let foods be your medicine and let medicine be your foods". Let all of us all exercise the values of the past wisdom to build a letter living and living health while enjoining these delicious drinks.

The smoothie for Prevention and treatment of Polyuria

Yield: 2 servings (about 8 ounces each)
1 1/2 cups sweet potato
1 cup mulberry fruit juice

1. Place all ingredients in a blender and puree about 1 minute
2. Blend on high speed about 1 minute or until the mixture is thick and the ice is well crushed. Add more green tea drink if needed
3. Serve immediately

Recent studies by some renowned institutions suggested that green tea(1) and grape may be the next generation of ingredient extracted from natural sources for reduced risk and treatment of Diuresis.
Polyuria is a condition of passing out too much urine not caused by increased liquid intake.
According to Second Hospital of Lanzhou University, in patients with diabetes, polyuria and hyperglycemia may induce bladder hypertrophy and late stage diabetic bladder dysfunction in urinary secretion(1). In fact, Short-term (3-week induction) diabetes- and polyuria-induced functional and morphological alterations of the bladder can mostly be reversed by Insulin treatment reversed in animal model(2).
According to Dr. Beshay E1 and Dr. Carrier S, anidxidant play an important role in reduced oxidative stress in induced apoptotic cells in the diabetic bladder smooth muscle cells cause of polyuria(3).

Vitamin E, a fat soluble found abundantly in sweet potato may be the next ingredient for prevention and treatment of Polyuria(Diuresis) in Kidney disease(4). According to the Osmangazi University Faculty of Medicine, Vitamin E exhibited protective effects on streptozotocin-induced diabetic rats in diabetic urinary bladder dysfunction, through decreased uroepithelial cells of diabetic bladder.apoptosis(4).

Mulberry, is also known as sang shen, used in traditional Chinese medicine for treatment of dizziness, tinnitus, insomnia, premature graying of the hair.... through tonifying blood and yin, native to China,
Cyanidin-3-O-β-D-glucopyranoside (C3G) isolated from mulberry fruit also exhibited protective effects against bladder dysfunction on streptozotocin-induced diabetic rats, according to the The Catholic University of Korea College of Medicine, study(5).

The effectiveness of Cooked Sweet Potato and Mulberry Fruit Juices may serve as cornerstones of pharmaceutical target for further studies in production of a potential medication for prevention and treatment of Polyuria(Diuresis) in Kidney diseases with little or no adverse effects.

People who are at high risk of Polyuria (Diuresis) due to kidney diseases and people with diabetic Polyuria (Diuresis) should drink no more than 4 servings daily, depending to digestive toleration.

Life style and diet pattern change are necessary.


References
(1) Roles of polyuria and hyperglycemia in bladder dysfunction in diabetes by Xiao N1, Wang Z, Huang Y, Daneshgari F, Liu G.(PubMed)
(2) Short-term diabetes- and diuresis-induced alterations of the bladder are mostly reversible in rats by Xiao N1, Huang Y, Kavran M, Elrashidy RA, Liu G.(PubMed)
(3) Oxidative stress plays a role in diabetes-induced bladder dysfunction in a rat model by Beshay E1, Carrier S.(PubMed)
(4) The protective effects of vitamin E on urinary bladder apoptosis and oxidative stress in streptozotocin-induced diabetic rats by Ustuner MC1, Kabay S, Ozden H, Guven G, Yucel M, Olgun EG, Ustuner D, Unal N, Degirmenci I.(PubMed)
(5) Protective effect of cyanidin-3-O-β-D-glucopyranoside fraction from mulberry fruit pigment against oxidative damage in streptozotocin-induced diabetic rat bladder by Ha US1, Bae WJ, Kim SJ, Yoon BI, Jang H, Hong SH, Lee JY, Hwang SY, Kim SW.(PubMed)



Most Common Diseases of elder: Respiratory Pleural disease: Pleural Plaques - Treatment In traditional Chinese medicine perspective

Kyle J. Norton(Scholar and Master of Nutrients, all right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

                                          Respiratory Disease

Respiratory Disease is defined as medical conditions, affecting the breathing organ and tissues including Inflammatory lung disease, Obstructive lung diseases, Restrictive lung diseases, Respiratory tract infections, trachea, bronchi, bronchioles, alveoli, the nerves and muscles breathing, etc,.

                   Pleural disease: Pleural Plaques

The pleura is a thin tissue covered by a layer of cells (mesothelial cells) that surrounds the lungs and lines the inside of the chest wall.
Pleural plaques is a medical condition as a result of exposure to asbestos that lead to accumulated plagues within the pleural cavity(a). Many diseases such as pneumonia, breast cancer, and heart failure can affect the pleural space.,therefore, it is often a secondary effect of another disease process.

The Treatment

In traditional Chinese medicine perspective(47)
Bai He Gu Jin Pian, one of many Chinese herb formula used by TCM to nourish lung Yin energy, moisten the lungs, transform phlegm, and stop cough may have a potential in treating lung diseases, including
1. Bai He
Bai He, is also known as Bulbus Lilii. The Sweet, slightly bitter, slightly cold herb has been used in TCM to treat Chronic cough, blood-streaked sputum, difficult to solve chronic low grade fever, insomnia with abundance of dreams, inability to concentrate, restlessness, irritability, etc., by enhancing the function of heart and lung function.
2. Di Huang
a. Sheng di huang
The bitter, sweet, bitter cold herb has been used in TCM as diuretic agent and to enhance heart function (small doses constrict the blood vessels and large doses dilate the blood vessel), decrease blood sugar, etc., as it clears Heat and cools the Blood, nourishes Yin, generates Fluids, cools the Upward-Blazing of Heart Fire, etc., by promoting the functions of heart, kidney, and liver channels.
b. Shu di huang
The bitter, sweet, bitter and warm herb has been used in as diuretic agent and to enhance heart function (small doses constrict the blood vessels and large doses dilate the blood vessel), decrease blood sugar, etc., as it clears Heat and cools the Blood (Sheng) as it nourishes Yin and Blood, tonifies the Essence, strengthens the Marrow, etc., by enhancing the functions of heart, kidney, and liver channels.
3. Mai Men Dong
Mai Dong or Mai Men Dong is also known as Ophiopogon tuber. The sweet and slightly bitter and cold herb has been used in TCM as anti-arrhythmia, Anti shock, anti bacterial agent and improve contraction of heart muscles, and improves toleration of lack of oxygen, protect heart muscle, enhance immune system, lower blood sugar, etc., as it moistens the Lung and Lung-Yin, benefits the Stomach, promotes generation of Body Fluids, clears the Heart, calms restlessness and anxiety, etc., by enhancing the functions of hear, lung and stomach channels.
4. Xuan Shen
Xuan Shen is also known as Figwort Root. The salty, sweet, bitter and cold herb has been used in TCM as anti bacterial, anti inflammatory, sedative, anti-pyretic agent and to lower blood pressure, blood sugar, etc., as it clears Heat, expels toxins, nourishes Yin, etc. by enhancing the functions of kidney, lung and stomach channels.
5. Bei Mu
Bei Mu is also known as Fritillary Bulb. The sweet, bitter and cold herb has been used in TCM as antibiotic and to raise blood pressure, stop cough, , increased blood sugar,etc. as it transforms Phlegm, calms cough; clears Heat, dissolves nodules, etc. by enhancing the functions of heart and lung channels.
6. Jie Geng
Jie geng is also known as Platycodon root. The bitter, acrid neutral herb has been used in TCM to get rid of phlegm, inhibit cough, treat bronchitis and sore throat, etc., by enhancing the function of lung channel.
7. Gan Cao
Gan Cao is also known as Licorice root. The sweet and neutral herb has been used in TCM as anti allergy, anti inflammation, anti ulcer, anti convulsion and to treat stomach weakness, tired and lack of strength, palpitation and short of breath, cough with abundance of phlegm, stomach and solar plexus pain, etc., as it tonifies the Spleen, benefits the Qi, moistens the Lungs, calms cough, deaf or acute pain, by enhancing all 12 channels.
8. Dang Gui
Dang Qui is also known as Angelica Root. The sweet, bitter, acrid and warm herb has been used in TCM to regulate the menses, lower lipids, reduce platelet coagulation and swelling, expel pus, relieve pain, etc/, as it tonifies and moves Blood, calms pain, moistens the Intestines, etc., by enhancing the function of heart, liver and spleen channels.
9. Bai Shao
Bai Shao also known as White Paeony Root, the bitter sour and cool herb has been used in TCM as anti-spastic, anticonvulsant, analgesic, sedative, antipyretic, anti-inflammatory, antibiotic agent and to owers blood pressure, dilates peripheral blood vessels etc., as it nourishes Blood and liver, preserves the Yin, clams pain;, etc., by promoting the function of liver and spleen channels.

All Forms of Arthritis are Curable
You Can Eliminate Osteoarthritis
By addressing the Underlying Causes through Clinical Trials and Studies

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Super foods Library, Eat Yourself Healthy With The Best of the Best Nature Has to Offer

Monday, April 4, 2016

Most Common Disease of 50Plus: The Clinical trials and Studies of Musculo-Skeletal disorders(MSDs) - Osteoarthritis: The Do and do not’s list

Kyle J. Norton (Scholar)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

Musculoskeletal disorders (MSDs) are medical condition mostly caused by work related occupations and working environment, affecting patients’ muscles, joints, tendons, ligaments and nerves and developing over time. A community sample of 73 females and 32 males aged 85 and over underwent a standardised examination at home. Musculoskeletal pain was reported by 57% of those interviewed. A major restriction of joint movement range was frequent in the shoulder but uncommon in other joints(1).

Types of Musculo-Skeletal disorders in elder(2)

1. Osteoarthritis
2. Gout
3. Rheumatoid Arthritis
4. Polymalagia Arthritis
5. Cervical myleopathy and spinal canal stenosis
6. Osteoporosis
7. Low back pain
8. Fibromyalgia          



                                                      Osteoarthritis


Osteoarthritis (OA), a form of arthritis, is defined as a condition of as a result of aging causes of wear and tear on a joint, affecting over 25 million people in the United States in alone. University of Porto Medical School indicated that one must understand the differences in prevalence and incidence estimates of osteoarthritis (OA), according to case definition, in knee, hip and hand joints(3).
The characteristics of osteoarthritis are aching pain(5), stiffness(6), or difficulty of moving the joint or joints(7). The pain usually gets worse in change of weather, at night and in the advanced diseases, the pain can occur even at rest(8). Today management of osteoarthritis (OA) focuses on pain relief and improved physical function through pharmacological, non pharmacological, and surgical treatments(4).

The Prevention and management The Do and do not’s list

1. Prevention recurrent injure to damage menisci
The meniscus is an important tissue because if its function in shock absorption and load distribution in the healthy knee joint(111). A meniscal tear can lead to knee osteoarthritis (OA), but knee OA can also lead to a spontaneous breakdown of meniscal tear and damage to meniscal structure(112). Meniscus damage or recurrent injure might be considered as a signifying feature of incipient OA in middle-aged and elderly people(113).

2. Take precaution if your occupation is at increased risk of osteoarthritis
Osteoarthritis (OA) is one of the most important diseases as it frequently affects the active age group of the population contributed to loss of working hours and of disability(114)(115)(117). Compressive, torsional, pulling and angular movements common in certain occupations or sports may result in injuries of soft tissue, thus increasing the development of OA(116).

3. Muscle strengthening and aerobic exercises
Enhanced muscle strengthening with neuromuscular electrical stimulation(118), aerobic exercises(119) and exercice(220) are effective in reducing pain and improving physical function in patients with mild to moderate OA of the knee(220).

4. Maintain a healthy weight(117)
Increased BMI and obesity are associated with more severe cartilage degeneration(121)(123) as assessed by both morphological and quantitative MRI measurements(122).

5. Avoid dehydration
Dehydration has shown to reduce the mobility of collagen amino acid residues and carbon sugar ring structures in glycosaminoglycans, according to University of Michigan(124) of that may effect the functions of cartilage and induce the risk of OA(125), but dehydration effects are reversible, through the restoration of molecular structure and mobility(124).

6. Avoid intake of inflammatory foods
Loading up on junk foods and fast foods contains high amount of trans fat of that increases the risk of inflammation(126) exhibit pro inflammatory effects(127) causes of osteoarthritis (OA)(128). Red meat, eggs, and wheat products all contain high amount of arachidonic acid, too much arachidonic acid may be worsen the inflammation process(129), etc.

7. Eat your fruits and vegetables
Fruits and vegetables containning high amount of nutrients and antioxidant(130), can enhance immune defense system(131)within the joint through direct infleuences of transferrin performance for reduction of inflammation(131)(132) as well as suppressing free radicals and the chain of free radicals reaction cause of elevating the swelling and promoting degeneration(133)(134).

8. Replace regular beverage with green tea
Epigallocatechin-3-gallate, a green tea polyphenol(135)(136), was found to be effective in reducing inflammatory cytokines induced inflammatory diseases(137)(138).

9. Etc.


Arthritis Is Curable
You Can Eliminate Osteoarthritis
By addressing the Underlying Causes through Clinical Trials and Studies


Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Super foods Library, Eat Yourself Healthy With The Best of the Best Nature Has to Offer


References
(1) Prevalence of rheumatic symptoms, rheumatoid arthritis, ankylosing spondylitis, and gout in Shanghai, China: a COPCORD study by Dai SM1, Han XH, Zhao DB, Shi YQ, Liu Y, Meng JM.(PubMed)
(2) Musculoskeletal Disorders in the Elderly by Ramon Gheno, Juan M. Cepparo, Cristina E. Rosca,1 and Anne Cotten(PMC)
(3) The effect of osteoarthritis definition on prevalence and incidence estimates: a systematic review by Pereira D1, Peleteiro B, Araújo J, Branco J, Santos RA, Ramos E.(PubMed)
(4) Effect of therapeutic aquatic exercise on symptoms and function associated with lower limb osteoarthritis: systematic review with meta-analysis by Waller B1, Ogonowska-Slodownik A2, Vitor M3, Lambeck J4, Daly D5, Kujala UM6, Heinonen A7.(PubMed)
(5) Effects of therapeutic ultrasound on pain, physical functions and safety outcomes in patients with kneeosteoarthritis: A systematic review and meta-analysis by Zhang C1, Xie Y2, Luo X3, Ji Q3, Lu C3, He C4, Wang P3.(PubMed)
(6) Oral intake of purple passion fruit peel extract reduces pain and stiffness and improves physical function in adult patients with knee osteoarthritis by Farid R1, Rezaieyazdi Z, Mirfeizi Z, Hatef MR, Mirheidari M, Mansouri H, Esmaelli H, Bentley G, Lu Y, Foo Y, Watson RR.(PubMed)
(7) Functional ability, mobility, and pain before and after knee replacement in patients aged 75 and older: a cross-sectional study by Limnell K1, Jämsen E, Huhtala H, Jäntti P, Puolakka T, Jylhä M.(PubMed)
(8) The symptoms of OA and the genesis of pain by David J. Hunter, MBBS PhD,1,2 Jason J. McDougall, BSc PhD,3 and Francis J. Keefe4(PubMed)
(111) The meniscus in knee osteoarthritis by Englund M1, Guermazi A, Lohmander LS.(PubMed)
(112) The role of the meniscus in knee osteoarthritis: a cause or consequence? by Englund M1, Guermazi A, Lohmander SL.(PubMed)
(113) Meniscus pathology, osteoarthritis and the treatment controversy by Englund M1, Roemer FW, Hayashi D, Crema MD, Guermazi A.(PubMed)
(114) Productivity loss due to presenteeism among patients with arthritis: estimates from 4 instruments by Zhang W1, Gignac MA, Beaton D, Tang K, Anis AH; Canadian Arthritis Network Work Productivity Group(PubMed)
(115) Occupational lifting is associated with hip osteoarthritis: a Japanese case-control study. by Yoshimura N1, Sasaki S, Iwasaki K, Danjoh S, Kinoshita H, Yasuda T, Tamaki T, Hashimoto T, Kellingray S, Croft P, Coggon D, Cooper C.(PubMed)(116) Occupation and osteoarthritis by Genti G.(PubMed)
(117) Risk factors for knee osteoarthritis in Japanese women: heavy weight, previous joint injuries, and occupational activities by Yoshimura N1, Nishioka S, Kinoshita H, Hori N, Nishioka T, Ryujin M, Mantani Y, Miyake M, Coggon D, Cooper C.(PubMed)
(118) Neuromuscular electrical stimulation for muscle strengthening in elderly with knee osteoarthritis - a systematic review by de Oliveira Melo M1, Aragão FA, Vaz MA.(PubMed)
(119) Effectiveness of exercise for osteoarthritis of the knee: A review of the literature. by Iwamoto J1, Sato Y, Takeda T, Matsumoto H.(PubMed)
(120) Effectiveness of exercise for osteoarthritis of the knee: A review of the literature by Iwamoto J1, Sato Y, Takeda T, Matsumoto H.(PubMed)
(121) Articular Cartilage Degeneration: Etiologic Association With Obesity by Deryk G. Jones, MD(PubMed)
(122) Correlation of magnetic resonance imaging-based knee cartilage T2 measurements and focal knee lesions with body mass index: thirty-six-month followup data from a longitudinal, observational multicenter study by Baum T1, Joseph GB, Nardo L, Virayavanich W, Arulanandan A, Alizai H, Carballido-Gamio J, Nevitt MC, Lynch J, McCulloch CE, Link TM.(PubMed)
(123) The evolving role of obesity in knee osteoarthritis by MaryFran R. Sowers and Carrie A. Karvonen-Gutierrez(PMC)
(124) Solid-state NMR spectroscopy provides atomic-level insights into the dehydration of cartilage by Xu J1, Zhu P, Morris MD, Ramamoorthy A.(PubMed)
(125) Geriatric Rehabilitation Manual By Timothy L. Kauffman
(126) Dietary intake of trans fatty acids and systemic inflammation in women by Mozaffarian D1, Pischon T, Hankinson SE, Rifai N, Joshipura K, Willett WC, Rimm EB.(PubMed)
(127) Health effects of trans-fatty acids: experimental and observational evidence by Mozaffarian D1, Aro A, Willett WC.(PubMed)
(128) Metabolic triggered inflammation in osteoarthritis by Wang X1, Hunter D2, Xu J3, Ding C4.(PubMed)
(129) Arachidonic acid metabolism: role in inflammation by Samuelsson B1.(PubMed)
(130) Antagonizing arachidonic acid-derived eicosanoids reduces inflammatory Th17 and Th1 cell-mediatedinflammation and colitis severity. by Monk JM1, Turk HF1, Fan YY1, Callaway E1, Weeks B2, Yang P3, McMurray DN4, Chapkin RS5.(PubMed)
(130) Effect of fruit and vegetable antioxidants on total antioxidant capacity of blood plasma by Harasym J1, Oledzki R2.(PubMed)
(131) Dietary antioxidants: immunity and host defense by Puertollano MA1, Puertollano E, de Cienfuegos GÁ, de Pablo MA.(PubMed)
(132) Cellular immunity in osteoarthritis: novel concepts for an old disease by Liossis SN1, Tsokos GC.(PubMed)
(133) Free Radicals, Antioxidants in Disease and Health by Lien Ai Pham-Huy,1 Hua He,2 and Chuong Pham-Huy3(PMC)
(134) Studies on free radicals, antioxidants, and co-factors by Khalid Rahman(PMC)
(135) New insights into the mechanisms of polyphenols beyond antioxidant properties; lessons from the green tea polyphenol, epigallocatechin 3-gallate by Hae-Suk Kim,a Michael J. Quon,c and Jeong-a Kima,b(PMC)
(136) Green tea catechin, epigallocatechin-3-gallate (EGCG): mechanisms, perspectives and clinical applications by Singh BN1, Shankar S, Srivastava RK.(PubMed)
(137) Dietary polyphenols and mechanisms of osteoarthritis by Shen CL1, Smith BJ, Lo DF, Chyu MC, Dunn DM, Chen CH, Kwun IS.(PubMed)
(138) Green tea: a new option for the prevention or control of osteoarthritis by Katiyar SK, Raman C.(PubMed)