Tuesday, September 27, 2016

Phytochemicals in Foods- The Effects of Myricetin

Kyle J. Norton(Scholar and Master of Nutrients, all right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.


                                     Myricetin



Myricetin is a flavonol, belong to the flavonoid in Flavonoids (polyphenols), found in many grapes, berries, fruits, vegetables, herbs, as well as other plants. It has been used as antioxidant to lower cholesterol, treat certain types of cancer, etc.

Health benefits
1. Anti cancers
In the investigation of dietary polyphenols as anticarcinogenic agents and the apoptotic effects of piceatannol and myricetin,found that apoptosis induced by piceatannol or myricetin occurs through an ROS-independent cell death pathway. In conclusion, piceatannol and myricetin synergistically induced apoptosis in HL-60 cells but not in HepG2 cells. These findings suggest that the potential anticarcinogenic properties of dietary polyphenols depend largely on the cell line used, according to "Selective apoptotic effects of piceatannol and myricetin in human cancer cells" by Morales P, Haza AI.(1)

2. Skin Cancer
In the affirmation of myricetin, a flavonol, found in many plants, including tea, berries, fruits, vegetables, and medicinal herbs and its chemopreventive effects on skin cancer found that myricetin was found to inhibit UVB-induced angiogenesis by targeting PI3-K in an SKH-1 hairless mouse skin tumorigenesis model. Raf kinase is a critical target for myricetin in inhibiting the UVB-induced formation of wrinkles and suppression of type I procollagen and collagen levels in mouse skin, according to "Myricetin is a potent chemopreventive phytochemical in skin carcinogenesis" by Kang NJ, Jung SK, Lee KW, Lee HJ.(2)

3. Colon cancer
In the research of Myricetin, a well known bioflavonoid and its protective effect on colon cancer found that Myricetin not only brought about significant decrease in the incidence of number of tumor bearing rats but also the tumor incidence.Myricetin supplementation significantly reduced liver TBARS. Further the anti oxidant enzymes like Catalase, Glutathione peroxidase and GSH were significantly rejuvenated following myricetin supplementation in a dose dependent manner, according to "Effect of myricetin on 1,2 dimethylhydrazine induced rat colon carcinogenesis" by Nirmala P, Ramanathan M.(3)

4. Pancreatic cancer
In the observation of the flavonoid myricetin and its effect on metastatic pancreatic cancer cell lines, found that myricetin resulted in tumor regression and decreased metastatic spread. Importantly, myricetin was non-toxic, both in vitro and in vivo, underscoring its use as a therapeutic agent against pancreatic cancer, according to the study of "Myricetin induces pancreatic cancer cell death via the induction of apoptosis and inhibition of the phosphatidylinositol 3-kinase (PI3K) signaling pathway" by Phillips PA, Sangwan V, Borja-Cacho D, Dudeja V, Vickers SM, Saluja AK.(4)

5. Antioxidant and cytotoxic activity
In the evaluation of extracted from plants containing phenolic compound, including flavonoid-galloyl glycoside [myricetin 3-O-(2',3'4'-tri-O-galloyl)-α-l-rhamnopyranoside] and theirs antioxidant and cytotoxic effect found that the methanol extract exhibited high antioxidant activity (SC(50) = 3.94 µg/ml), which is correlated with its phenolic content. The extract also showed cytotoxic activity against Hep G2 (IC(50) value 1.41 µg/ml) confirming its anticancer activity against hepatocellular carcinoma, according to the study of "Antioxidant and cytotoxic activity of polyphenolic compounds isolated from the leaves of Leucenia leucocephala" by Haggag EG, Kamal AM, Abdelhady MI, El-Sayed MM, El-Wakil EA, Abd-El-Hamed SS.(5)

6. Liver cancer
In the examination of study the mechanism of myricetin and its effect on the HepG-2 cell line found that Myricetin significantly inhibits the proliferation and induces the apoptosis of HepG-2 in a dose-dependent manner, which is accompanied with G2/M and S phase arrest. In addition, myricetin also increases the activation of caspase 3,9 and results in a depolarization and delta psi m collapse in a dose-dependent manner, according to "[Studies on mechanism ofmyricetin-induced apoptosis in human hepatocellular carcinoma HepG-2 cells].[Article in Chinese]" by Zhang X, Ling Y, Yu H, Ji Y.(6)

7. Synovial sarcoma cells
In observation of myricetin and its effect on the destruction cartilage and bone in RA joint found that Myricetin significantly decreased IL-1beta-induced production of IL-6 and MMP-1 in synovial cells. Moreover, myricetin diminished the phosphorylation of Jun NH2-terminal kinase (JNK) and p38 MAPK. These results suggest that myricetin reduces the production of MMP and IL-6 in SW982 cells by inhibiting (mitogen-activated protein kinases)MAPKs (JNK and p38), according to "Myricetin inhibits IL-1beta-induced inflammatory mediators in SW982 human synovial sarcoma cells" by Lee YS, Choi EM.(7)

8. Leukemia
In the comparison of the cytotoxic effect of 11 flavonoids on chronic myeloid leukemia (erythroblast crisis) K562 cells and peripheral blood mononuclear cells from healthy donors found that Baicalein and myricetin had a specific cytotoxic effect on leukemia cells, according to "Cytotoxic effect of flavonoids on leukemia cells and normal cells of human blood" by Romanouskaya TV, Grinev VV.(8)

9. Cell transformation
In the analyzing myricetin and its effect on cellular processes including cell growth, proliferation, and apoptosis found that myricetin inhibited Akt-mediated activator protein-1 (AP-1) transactivation, cyclin D1 expression and cell transformation. Overall, our results indicate that Akt is a direct target for myricetinto inhibit cell transformation, acccording to "Akt is a direct target for myricetin to inhibit cell transformation" by Kumamoto T, Fujii M, Hou DX.(9)

10. Esophageal cancer
In the investigation of flavones and flavonols and their effect on on esophageal squamous cell carcinoma cell line (KYSE-510) found that the cytotoxic potency of these compounds was in the order of: luteolin>quercetin>chrysin>kaempferol>apigenin>myricetin. . Flow cytometry and DNA fragmentation analysis indicated that the cytotoxicity induced by flavones and flavonols was mediated by G(2)/M cell cycle arrest and apoptosis, according to "Cytotoxicity of flavones and flavonols to a human esophageal squamous cell carcinoma cell line (KYSE-510) by induction of G2/M arrest and apoptosis' by Zhang Q, Zhao XH, Wang ZJ.(10)

11. Antitumour and anti-inflammatory activities
In the observation of of flavonoids isolated from Byrsonima crass and its effect on mammary tumour cells LM2, found that almost all the samples showed inhibitory activity to the release of NO but not of TNF-alpha. Of all substances tested, flavonoids 2 (quercetin) and 6 (myricetin) may show promising activity in the treatment of murine breast cancer by immunomodulatory and antiproliferative activities, according to "Isolated flavonoids against mammary tumour cells LM2" by Carli CB, de Matos DC, Lopes FC, Maia DC, Dias MB, Sannomiya M, Rodrigues CM, Andreo MA, Vilegas W, Colombo LL, Carlos IZ.(11)

12. Ovarian cancer
In the research of inverse associations with certain flavonoids or flavonoid subclasses (myricetin, kaempferol, quercetin, luteolin, and apigenin) and ovariancancer risk, found that In analyses of each individual flavonoid, only intake of apigenin was associated with a borderline significant decrease in risk (RR, highest vs. lowest quintile = 0.79, 95% CI = 0.59-1.06; p-trend = 0.26), and this association was significant after adjustment for intake of the other 4 individual flavonoids (comparable RR = 0.72, 95% CI = 0.53-0.98; p-trend = 0.09), according to "Flavonoid intake and ovarian cancer risk in a population-based case-control study" by Gates MA, Vitonis AF, Tworoger SS, Rosner B, Titus-Ernstoff L, Hankinson SE, Cramer DW.(12)

13. Prostate cancer
In the selection of several potential uPA inhibitors (antipain, leupeptin, folic acid, rosmarinic acid, lavendustin A, fisetin, myricetin, tolfenamic acid) and examination of theirs effects in prostate cancer found that a proper diet rich in uPA-inhibiting nutraceuticals might support the prevention of prostrate cancer and be a supportive tool in prostate cancer treatment, according to "Nutraceutical inhibitors of urokinase: potential applications in prostate cancer prevention and treatment" by Jankun J, Selman SH, Aniola J, Skrzypczak-Jankun E.(13)

14. Breast cancer
In study of red wine intake and its beneficial health effects on the proliferation of hormone-dependent breast cancer cells found that the estrogenic activity of PIC(piceatannol) and MYR(myricetin) might be considered at least as a potential factor in the association of red wine intake and breast tumors, particularly in postmenopausal women, according to "The red wine phenolics piceatannol andmyricetin act as agonists for estrogen receptor alpha in human breast cancercells" by Maggiolini M, Recchia AG, Bonofiglio D, Catalano S, Vivacqua A, Carpino A, Rago V, Rossi R, Andò S.(14)

15. Etc.

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Reverse Infertility And Get Pregnant Naturally
Using Holistic Ancient Chinese Medicine



Sources
(1) http://www.ncbi.nlm.nih.gov/pubmed/21935971
(2) http://www.ncbi.nlm.nih.gov/pubmed/21793847
(3) http://www.ncbi.nlm.nih.gov/pubmed/21699017
(4) http://www.ncbi.nlm.nih.gov/pubmed/21676539
(5) http://www.ncbi.nlm.nih.gov/pubmed/21595573
(6) http://www.ncbi.nlm.nih.gov/pubmed/20617691
(7) http://www.ncbi.nlm.nih.gov/pubmed/20403460
(8) http://www.ncbi.nlm.nih.gov/pubmed/19902097
(9) http://www.ncbi.nlm.nih.gov/pubmed/19504174
(10) http://www.ncbi.nlm.nih.gov/pubmed/19397994
(11) http://www.ncbi.nlm.nih.gov/pubmed/19323263
(12) http://www.ncbi.nlm.nih.gov/pubmed/19117058
(13) http://www.ncbi.nlm.nih.gov/pubmed/16820913
(14) http://www.ncbi.nlm.nih.gov/pubmed/16216908

Phytochemicals in Foods- The Effects of Kaempferol

Kyle J. Norton(Scholar and Master of Nutrients, all right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.


                                   Kaempferol

Kaempferol is type of flavonoid found in tea, broccoli, Delphinium, Witch-hazel, grapefruit,cabbage, kale, beans, endive, etc., and may be a potential phytochemical in preventing arteriosclerosis, oxidative damage of cells, lipids and DNA, etc.


Health Benefits
1. Hypoglycemic and antioxidant effects
In the investigation of the effects of kaempferol-3,7-O-(alpha)-dirhamnoside (kaempferitrin) on serum glucose levels for its antioxidant potential and hypoglycemic effect found that the hypoglycemic effect of kaempferitrin in diabetic rats was evident at all doses tested (50, 100, and 200 mg/kg), and this profile was maintained throughout the period studied for both higher doses while the compound showed high reactivity with 1,1-diphenyl-2-picryl hydrazyl (DPPH), IC(50) of 84.0 +/- 7.8 microM, inhibited myeloperoxidase activity with K(0.5) = 86 +/- 9.9 microM, and decreased lipid peroxidation, induced by ascorbyl radical either in microsomes or in asolectin and phosphatidylcholine liposomes, with IC(50)'s of 320 +/- 14.1, 223 +/- 8.3, and 112 +/- 8.8 microM, respectively, according to the study of "Hypoglycemic effect and antioxidant potential of kaempferol-3,7-O-(alpha)-dirhamnoside from Bauhinia forficata leaves" by de Sousa E, Zanatta L, Seifriz I, Creczynski-Pasa TB, Pizzolatti MG, Szpoganicz B, Silva FR.(1)

2. Anti-inflammatory effects
In the evaluation of Kaempferol-3-O-sophoroside (KPOS), isolated from the leaves of cultivated mountain ginseng and its Anti-inflammatory effects, found that that KPOS possesses barrier integrity activity, inhibitory activity on cell adhesion and migration to endothelial cells by blocking the activation of NF-κB expression and production of TNF-α, thereby endorsing its usefulness as therapy for vascularinflammatory diseases, according to "Anti-inflammatory effects of kaempferol-3-O-sophoroside in human endothelial cells" by Kim TH, Ku SK, Lee IC, Bae JS.(2)

3. Antimicrobial effect
In the observation of kaempferol, myricetin, naringin, and rutin were the major flavonoids present in the pericarp and theirs antimicrobial effect found that the anti fungi activity was only found in seed extract against Aspergillus niger (1.87 cm) at concentration of 0.3 mg/well. From the results obtained, P. macrocarpa fruit could be considered as a natural antimicrobial source due to the presence of flavonoid compounds, according to the study of "Flavonoid Analyses and AntimicrobialActivity of Various Parts of Phaleria macrocarpa (Scheff.) Boerl Fruit" by Hendra R, Ahmad S, Sukari A, Shukor MY, Oskoueian E.(3)

4. Cardioprotective effect
In the analyzing the LGP consisted of 92% carbohydrate and was rich in flavans, anthocyanins, quercetin, myricetin, kaempferol, and resveratrol and it effect in cardiovascular diseases found that through alterations in lipoprotein metabolism, oxidative stress, and inflammatory markers, LGP intake beneficially affected key risk factors for coronary heart disease in both pre- and postmenopausal women, according to "Grape polyphenols exert a cardioprotective effect in pre- and postmenopausal women by lowering plasma lipids and reducing oxidative stress" by Zern TL, Wood RJ, Greene C, West KL, Liu Y, Aggarwal D, Shachter NS, Fernandez ML.(4)

5. Neuroprotective effects
In the investigationthe neuroprotective effects of kaempferol in the mouse model of Parkinson's disease found that kaempferol could prevent the loss of TH-positive neurons induced by MPTP. Taken together, we propose that kaempferol has shown anti-Parkinsonian properties in our studies. More work is needed to explore detailed mechanisms of action, according to"Neuroprotective effect ofkaempferol against a 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced mouse model of Parkinson's disease" by Li S, Pu XP.(5)

6. Osteoporosis
In observation of two widespread flavonols, quercetin and kaempferol and their anti anti-osteoporotic effects found that both flavonols significantly increased (alkaline phosphatase) ALP activity and concluded that flavonols derivatives as quercetin and kaempferol can stimulate osteoblastic activity. Such compounds may represent new pharmacological tools for the treatment of osteoporosis, according to "Stimulatory effect of naturally occurring flavonols quercetin andkaempferol on alkaline phosphatase activity in MG-63 human osteoblasts through ERK and estrogen receptor pathway" by Prouillet C, Mazière JC, Mazière C, Wattel A, Brazier M, Kamel S.(6)

7. Estrogenic effects
In the research of Kaempferol (K), a flavonol and its anti-osteoclastogenic effect inovariectomized adult Sprague-Dawley rats found that The K-treated group exhibited significantly higher bone mineral density (BMD) in the trabecular regions (femur neck, proximal tibia and vertebrae) and lower serum ALP (bone turnover marker), according to "Kaempferol has osteogenic effect in ovariectomized adult Sprague-Dawley rats" by Trivedi R, Kumar S, Kumar A, Siddiqui JA, Swarnkar G, Gupta V, Kendurker A, Dwivedi AK, Romero JR, Chattopadhyay N.(7)

8. Anxiolytic-like response
In the comparison of three different regions of Mexico to compare their flavonoid content, including quercetin and kaempferol glycosides and anxiolytic-like response flavonoid content and anxiolytic-like response found that cince quercetin and kaempferol aglycons demonstrated anxiolytic-like response and that no difference in the pharmacological evaluation was observed between these three Mexican Tilias, we suggest that this pharmacological effect of Tilia inflorescences involves these flavonoids occurrence independently of the kind of glycosides present in the samples, according to "HPLC/MS analysis and anxiolytic-like effect of quercetin and kaempferol flavonoids from Tilia americana var. mexicana" by Aguirre-Hernández E, González-Trujano ME, Martínez AL, Moreno J, Kite G, Terrazas T, Soto-Hernández M.(8)

9. Anti cancers
In the investigation of Moringa oleifera leaf extract (MLE) found to have the presence of of phenolics such as quercetin and kaempferol and it anti cancer effect found that the leaf extracts from M. oleifera had strong antiproliferation and potent induction of apoptosis. Thus, it indicates that M. oleifera leaf extracts has potential for cancer chemoprevention and can be claimed as a therapeutic target for cancer, according to the study of "Antiproliferation and induction of apoptosis by Moringa oleifera leaf extract on human cancer cells" by Sreelatha S, Jeyachitra A, Padma PR.(9)

10. Analgesic and anti-inflammatory effects
In the evaluation of analgesic and anti-inflammatory activities of Cassia siamea Lam stem bark extracts, including four major families of compounds present in the plant may explain these activities: triterpenes (lupeol, oleanolic acid, ursolic acid, friedelin, betulin), flavonoids (apigenin, kaempferol, luteolin), anthraquinones (emodin), phytosterols (stigmasterol, beta-sitosterol). found that At the doses used (100, 200, and 400mg/kg) ethanol and water extracts showed significant and dose-dependent analgesic and anti-inflammatory effects, according to "Analgesic and anti-inflammatory effects of Cassia siamea Lam. stem bark extracts" by Nsonde Ntandou GF, Banzouzi JT, Mbatchi B, Elion-Itou RD, Etou-Ossibi AW, Ramos S, Benoit-Vical F, Abena AA, Ouamba JM.

11. Anti-allergic effects
In the observation of flavonoid kaempferol glycoside compounds derived from plants and theirs anti allergic effects found that GRRK treatment before or after established allergic lung disease down-regulates key asthmatic features. Therefore, (alpha-l-ramnopiranosil]-7-O-alpha-l-ramnopiranosil-kaempferol) GRRK has a potential clinical use for the treatment of allergic asthma, according to the study of "Preventive and curative glycoside kaempferol treatments attenuate the TH2-driven allergic airway disease" by Medeiros KC, Faustino L, Borduchi E, Nascimento RJ, Silva TM, Gomes E, Piuvezam MR, Russo M.(11)

12. Etc.

Pregnancy Miracle
Reverse Infertility And Get Pregnant Naturally
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Sources
(1) http://www.ncbi.nlm.nih.gov/pubmed/15165145
(2) http://www.ncbi.nlm.nih.gov/pubmed/22113342
(3) http://www.ncbi.nlm.nih.gov/pubmed/21747685
(4) http://www.ncbi.nlm.nih.gov/pubmed/16046716
(5) http://www.ncbi.nlm.nih.gov/pubmed/21804220
(6) http://www.ncbi.nlm.nih.gov/pubmed/15013846
(7) http://www.ncbi.nlm.nih.gov/pubmed/18400372
(8) http://www.ncbi.nlm.nih.gov/pubmed/19799990
(9) http://www.ncbi.nlm.nih.gov/pubmed/21385597
(10) http://www.ncbi.nlm.nih.gov/pubmed/19799981
(11) http://www.ncbi.nlm.nih.gov/pubmed/19755174

Food Therapy: Poultry and Lean Meats - Beef, lean organic

Kyle J. Norton(Scholar and Master of Nutrients, all right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.                     

                             Beef, lean organic


Lean meats are considered as animal fresh of which most fats are withdrawn before consuming to reduce the amount of sutured fat and cholesterol. Although some people insist that meats with fat are highly tasty, but the consequence of eating too much fat can damp the health of your body, leading to all kinds of diseases. Because of the use of growth hormone and selective breeding for commercial purposes, it is advised only eating lean meats from organic farm.

Nutrients
1. Protein
2. Fat
3. Vitamin A
4. Vitamin B complex
5. Vitamin C
6. Vitamin D
7. Vitamin E
8. Sodium
9. Selenium
10. Phosphorus
11. Iron
12. Zinc
13. Etc.

Health Benefits
A. Health benefits according to studies
1. Nutrients
In the assessment of the nutrients in lean beef found that Total beef consumed among adults 19 to 50 and 51+ years was 49.3 +/- 1.4 g (1.74 oz/d) and 37.1 +/- 1.2 g (1.31 oz/d), respectively. In adults 19 to 50 and 51+ years, LB contributed 3.9% and 3.7% to total energy; 4.5% and 4.1% to total fat, 3.8% and 3.6% to saturated fatty acids; 13% and 11% to cholesterol intake; 15% and 14% to protein; 25% and 20% to vitamin B(12); 23% and 20% to zinc; and 8% and 7% to iron, respectively. Beef was also an important food source of many other nutrients, including niacin, vitamin B(6), phosphorus, and potassium. In addition, beefprovided only 1% of total sodium intake and concluded that Consumption of beefcontributed significantly to intake of protein and other key nutrients by US adults, according to "Lean beef contributes significant amounts of key nutrients to the diets of US adults: National Health and Nutrition Examination Survey 1999-2004" by Zanovec M, O'Neil CE, Keast DR, Fulgoni VL 3rd, Nicklas TA.(a)

2. Hypercholesterolemic
In the comparison of the effects on lipoprotein profiles in hypercholesterolemic men with consumption of beef with that of fish and poultry found that that an American Heart Association diet with a high polyunsaturated-to-saturated fatty acid ratio and high fiber content induced numerous favorable changes in coronary artery disease risk factors in hypercholesterolemic men, regardless of the protein source, according to "Plasma lipids and lipoproteins in hypercholesterolemic men fed a lipid-lowering diet containing lean beef, lean fish, or poultry" by Beauchesne-Rondeau E, Gascon A, Bergeron J, Jacques H.(b)

3. Weight loss and improved lipid
In the investigation of Conflicting recommendations are prevalent regarding the appropriateness of red meat versus white meat consumption found that that weight loss and improved lipid profile can be accomplished through diet and exercise, whether the dietary protein source is lean beef or chicken, according to "Weight loss and total lipid profile changes in overweight women consuming beef or chicken as the primary protein source" by Melanson K, Gootman J, Myrdal A, Kline G, Rippe JM.(c)

4. Cardiovascular health
In the examination of the effects of dietary protein intake on energy restriction (ER)-induced changes in body mass and body composition found that overweight postmenopausal women can achieve significant weight loss and comparable short-term improvements in body composition and lipid-lipoprotein profile by consuming either a moderate-protein (25% of energy intake) poultry- or beef-containing diet or a lacto-ovo vegetarian protein (17% of energy intake) diet, according to "Protein intake during energy restriction: effects on body composition and markers of metabolic and cardiovascular health in postmenopausal women" by

Mahon AK, Flynn MG, Stewart LK, McFarlin BK, Iglay HB, Mattes RD, Lyle RM, Considine RV, Campbell WW.(d)

5. Diabetes
In random sequence, 50 g protein in the form of very lean beef or only water at 0800 h and studied over the subsequent 8 h found that the amount of glucose appearing in the circulation was only approximately 2 g. The peripheral plasma glucose concentration decreased by approximately 1 mM after ingestion of either protein or water, confirming that ingested protein does not result in a net increase in glucose concentration, and results in only a modest increase in the rate of glucose disappearance, according to "Effect of protein ingestion on the glucose appearance rate in people with type 2 diabetes" by Gannon MC, Nuttall JA, Damberg G, Gupta V, Nuttall FQ.(e)

6. Etc.
B. Health benefits according to concentration
1. TrytophanTryptophan is one of the 10 essential amino acids which the body uses to synthesize the proteins for brain cells need, thus enhancing the nerve cells in information transmitting between themselves and cells in the parts of the body that reduces the risk of anxiety and depression, according to the study of "The effects of tryptophan depletion on neural responses to emotional words in remitted depression" by Roiser JP, Levy J, Fromm SJ, Nugent AC, Talagala SL, Hasler G, Henn FA, Sahakian BJ, Drevets WC.(I)

2. ProteinIn the research of the importance of dietary proteins influence body weight by affecting four targets for body weight regulation: satiety, thermogenesis, energy efficiency, and body composition, found that Ingestion of dietary proteins in diabetes type 1 exerts a delayed postprandial increase in blood glucose levels due to protein-induced stimulation of pancreatic glucagon secretion. Higher than minimal amounts of protein in the diet needed for nitrogen balance may play animportant role for the increasing number of elderly obese subjects in our industrialized societies, since proteins exert beneficial effects in the conditions of overweight, metabolic syndrome, cardiovascular risk factors, bone health, and sarcopenia. Adverse effects of increased dietary proteins have been observed in subjects with renal impairment- this problem is frequently observed in the elderly, hypertensive, and diabetic population. Nevertheless, dietary proteins deserve more attention than they have received in the past, according to "Dietary proteins in obesity and in diabetes" by Keller U.(II)

3. Vitamin B complexBeef contains high levels of vitamin B complex, including niacin, thiamin, riboflavin and B6, which aid each other for the body's metabolism, according to the article of "Vitamin B Complex", posted in the Americam cancer societ, the author wrote that B vitamins are essential for growth, development, and a variety of other bodily functions. They play a major role in the activities of enzymes, proteins that regulate chemical reactions in the body(III), the formation of red blood cell formation and promoting the effectiveness of nervous system, according to the study of "The effect of 90 day administration of a high dosevitamin B-complex on work stress" by Stough C, Scholey A, Lloyd J, Spong J, Myers S, Downey LA., posted in PubMed (IV).

4. ZincIn the assessment of zinc and its effect on thyroid hormone andtestosterone levels found that exercise decreases thyroid hormones andtestosterone in sedentary men; however, zinc supplementation prevents this decrease. Administration of a physiologic dose of zinc can be beneficial to performance, according to "Effect of fatiguing bicycle exercise on thyroid hormone and testosterone levels in sedentary males supplemented with oralzinc" by Kilic M.(V)

5. SeleniumSelenium is considered as one of a powerful antioxidant in protection of free radical causes of cancer, according to study of "Low doses of seleniumspecifically stimulate the repair of oxidative DNA damage in LNCaP prostatecancer cells" by de Rosa V, Erkekoğlu P, Forestier A, Favier A, Hincal F, Diamond AM, Douki T, Rachidi W.(VI)
6. Etc.

C. Other health benefits
1. Enzymes
Lean meat contains a complete amino enzymes that are essential for the building blocks of about everything in our body including from enzymes and hormones to bones, muscles and skin., according to the article of "Protein" posted in Wikipedia(1), the writer wrote that proteins are essential parts of organisms and participate in virtually every process within cells. Many proteins are enzymes that catalyze biochemical reactions and are vital to metabolism. Proteins also have structural or mechanical functions.

2. Free radical scavenger
Vitamin C is one of antioxidant that improves the immune system in fighting against the forming of free radicals and invasion of foreign virus and bacteria, thus reducing the risk of abnormal cell growth, infection and inflammation according to the study of "Dietary antioxidants: immunity and host defense" by Puertollano MA, Puertollano E, de Cienfuegos GÁ, de Pablo MA., posted in PubMed(2)

3. Improve the nutrient transportation
The high levels of iron helps in maintaining high levels of energy and oxygen through the bloodstream as it enhances the function of blood in oxygen absorption, reduces the risk of iron deficiency anemia and improves the menstrual health for teenage girls and women in their child-bearing years, according to the study of "[Menstrual blood loss and iron nutritional status in female undergraduate students].[Article in Chinese]" by Li J, Gao Q, Tian S, Chen Y, Ma Y, Huang Z., posted in PubMed(3)

4. Osteoporosis
Beside aiding the body in absorption of calcium which is an essential mineral for healthy bone, it also play an important role in relaxing muscle thus reducing the risk of metal cramps and pain and fibromyalgia, according to the study of "The relationship between serum antioxidant vitamins, magnesium levels, and clinical parameters in patients with primary fibromyalgia syndrome.as well as improving insulin reaction to blood sugar level" by Sakarya ST, Akyol Y, Bedir A, Canturk F., posted in PubMed(4)

5. Nerve cells
Beside phosphorus is an essential minerals in maximizing the effectiveness in calcium, according to the atudy of "The Abnormal Phenotypes of Cartilage and Bone in Calcium-Sensing Receptor Deficient Mice Are Dependent on the Actions of Calcium, Phosphorus, and PTH" by Liu J, Lv F, Sun W, Tao C, Ding G, Karaplis A, Brown E, Goltzman D, Miao D., posted in PubMed (5), it also aids the function of digestive system in absorbing B vitamins, enhances the brain cells in information transmitting.

6. Etc.


Side effect
1. Although it is lean, it still contains a measure amount of fat, therefore, it is advised that people with history of heat diseases, stroke, high blood pressure and bad cholesterol to supplement their diet with plant protein.
2. It may cause stress to kidneys for certain people and reduce the absorption of calcium, if eating in large amount.
3. Etc.


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Sources
(a) http://www.ncbi.nlm.nih.gov/pubmed/20650344
(b) http://www.ncbi.nlm.nih.gov/pubmed/12600847
(c) http://www.ncbi.nlm.nih.gov/pubmed/12714091
(d) http://www.ncbi.nlm.nih.gov/pubmed/17536130
(e) http://www.ncbi.nlm.nih.gov/pubmed/11238483

(I) http://www.ncbi.nlm.nih.gov/pubmed/19539268
(II) http://www.ncbi.nlm.nih.gov/pubmed/22139563
(III) http://www.cancer.org/Treatment/TreatmentsandSideEffects/ComplementaryandAlternativeMedicine/HerbsVitaminsandMinerals/vitamin-b-complex
(IV) http://www.ncbi.nlm.nih.gov/pubmed/21905094
(V) http://www.ncbi.nlm.nih.gov/pubmed/17984944
(VI) http://www.ncbi.nlm.nih.gov/pubmed/22145923

1. http://en.wikipedia.org/wiki/Protein
2. http://www.ncbi.nlm.nih.gov/pubmed/21506934
3. http://www.ncbi.nlm.nih.gov/pubmed/21560310
4. http://www.ncbi.nlm.nih.gov/pubmed/21347604
5. http://www.ncbi.nlm.nih.gov/pubmed?term=The%20Abnormal%20Phenotypes%20of%20Cartilage%20and%20Bone%20in%20Calcium-Sensing%20Receptor%20Deficient%20Mice%20Are%20Dependent%20on%20the%20Actions%20of%20Calcium%2C%20Phosphorus%2C%20and%20PTH


Herbal Therapy: The Aloe Vera effects on Gingivitis

Kyle J. Norton(Scholar, Master of Nutrients), all right reserved.
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

                 
                                         Aloe Vera

Aloe Vera is species of succulent plant in the genus Aloe, belonging to the Family Xanthorrhoeaceae, native to Sudan. It has become very popular for commercial cultivation due to its health benefits. Aloe vera has been used in herbal medicine in treating many kinds of disease, including wound, burn healing, minor skin infections, sebaceous cysts, diabetes, and elevated of cholesterol, etc. It is also one of many popular herb studied in scientific ways with some conflicted results.


                                                     Gingivitis

Gingivitis is defined as a condition of Inflammation of Gum Diseases.

The Ingredients
The ten main areas of chemical constituents of Aloe vera include: amino acids, anthraquinones, enzymes, minerals, vitamins, lignins, monosaccharide, polysaccharides, salicylic acid, saponins, and sterols.

The benefits
Aloe Vera anti-inflammatory property may be the result of the plant used in treatment of gum diseases. In the sudy of 45 patients who were diagnosed with plaque-induced gingivitis were included, aloe mouth wash is proven to be the most potential in reduction in gingival inflammation caused by plagues. Other in the the randomized, controlled, and double-blind study, a total of 148 systemically healthy subjects, showed statistically significant decrease in PI, MGI, and BI scores after the rinse regimen began in comparison with the use of chlorhexidine. But Dr. de Oliveira SM, and the research team in comparison of Aloe vera and fluoridated dentifrice, found that here was a significant reduction on plaque and gingivitis in both groups, but no statistically significant difference was observed among them (p>0.01), Aloe vera did not show any additional effect on plaque and gingivitis control compared to the fluoridated dentifrice.

The Side effects
1. Hepatitis
Some researchers concerned that the over use of oral aloe vera may contribute to acute hepatitis, according to the study of "Oral aloe vera-induced hepatitis" by Bottenberg MM, Wall GC, Harvey RL, Habib S., posted in PubMed
2. Diarrhea, caused by the laxative effect of oral use of Aloe Vera
3. oral use of Aloe Vera may cause abdominal cramps and pain
4. It may cause of rheumatoid arthritis symptoms as a result of collagen in the plant
5. Etc. 


References
(1) Aloe barbadensis Mill. formulation restores lipid profile to normal in a letrozole-induced polycystic ovarian syndrome rat Model (PubMed)
(2) ALOE VERA by Gertrude Baldwin,http://www.herballegacy.com/Baldwin_Chemical.html
(3) Aloe vera: It's effect on gingivitis by Ajmera N, Chatterjee A, Goyal V.(PubMed)
(4) A randomized, double-blind clinical study to assess the antiplaque and antigingivitis efficacy of Aloe vera mouth rinse by Chandrahas B, Jayakumar A, Naveen A, Butchibabu K, Reddy PK, Muralikrishna T.(PubMed)
(5) Effect of a dentifrice containing Aloe vera on plaque and gingivitis control. A double-blind clinical study in humans by de Oliveira SM, Torres TC, Pereira SL, Mota OM, Carlos MX.(PubMed)
(7) Oral aloe vera-induced hepatitis(PubMed)(8) Oral type II collagen in thetreatment of rheumatoid arthritis. A six-month double blind placebo-controlledstudy(PubMed)


Herbal Therapy: The Aloe Vera effects on Polycystic Ovarian Syndrome

Kyle J. Norton(Scholar, Master of Nutrients), all right reserved.
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

                 
                                         Aloe Vera

Aloe Vera is species of succulent plant in the genus Aloe, belonging to the Family Xanthorrhoeaceae, native to Sudan. It has become very popular for commercial cultivation due to its health benefits. Aloe vera has been used in herbal medicine in treating many kinds of disease, including wound, burn healing, minor skin infections, sebaceous cysts, diabetes, and elevated of cholesterol, etc. It is also one of many popular herb studied in scientific ways with some conflicted results.


                                   Polycystic Ovarian Syndrome

Polycystic Ovarian Syndrome is defined as endocrinologic diseases caused by undeveloped follicles clumping on the ovaries that interferes with the function of the normal ovaries as resulting of enlarged ovaries, leading to hormone imbalance( excessive androgen), resulting in male pattern hair development, acne,irregular period or absence of period, weight gain and effecting fertility. It effects over 5% of women population or 1 in 20 women. According to the study by Desai BN, Maharjan RH, Nampoothiri LP. almost 70% PCOS women have abnormal serum lipid levels (dyslipidemia) and 50% of these women are obese. Several classes of pharmacological agents have been used to manage dyslipidemia. However, studies have shown adverse effects associated with these drugs.

The Ingredients
The ten main areas of chemical constituents of Aloe vera include: amino acids, anthraquinones, enzymes, minerals, vitamins, lignins, monosaccharide, polysaccharides, salicylic acid, saponins, and sterols.They all work together in a synergistic way to create healing and health giving benefits, according to Gertrude Baldwin in the article of THE BENEFITS OF THE USE OF ALOE VERA IN HERBAL PREPARATIONS.

The Benefits
Aloe Vera may be a potential herb in treating Polycystic Ovarian Syndrome by enhancing the reductions of plasma triglyceride and LDL cholesterol levels, with an increase in HDL cholesterol or by restoring the ovarian steroid status. According to the study of PCOS was induced in Charles Foster female rats by oral administration of non-steroidal aromatase inhibitor letrozole (0.5 mg/kg body weight, 21 days), AVG treated PCOS rats exhibited significant reduction in plasma triglyceride and LDL cholesterol levels, with an increase in HDL cholesterol. The gel treatment also caused reversion of abnormal estrous cyclicity, glucose intolerance, and lipid metabolizing enzyme activities, bringing them to normal. Other study also indicated that Aloe vera gel formulation exerts a protective effect in against the PCOS phenotype by restoring the ovarian steroid status, and altering key steroidogenic activity. This can be attributed to phyto-components present in the extract.
Dr.Pérez YY and the research team in the study of Effect of a polyphenol-rich extract from Aloe vera gel on experimentally induced insulin resistance in mice also indicated that decreasing significantly both body weight (p < 0.008) and blood glucose levels of Aloe, calculated using the homeostasis model assessment for insulin resistance (HOMA-IR) formula by the polyphenol-rich extract from Aloe vera.
Also in the confirmation of above result, study of Aloe vera leaves on blood glucose level in type I and type II diabetic rat models, vera leaf pulp extract showed hypoglycaemic activity on IDDM and NIDDM rats, the effectiveness being enhanced for type II diabetes in comparison with glibenclamide. On the contrary, A. vera leaf gel extract showed hyperglycaemic activity on NIDDM rats. It may therefore be concluded that the pulps of Aloe vera leaves devoid of the gel could be useful in the treatment of non-insulin dependent diabetes mellitus. Where non-diabetic (ND), type I (IDDM) and type II (NIDDM) diabetic rats.

The Side effects
1. Hepatitis
Some researchers concerned that the over use of oral aloe vera may contribute to acute hepatitis, according to the study of "Oral aloe vera-induced hepatitis" by Bottenberg MM, Wall GC, Harvey RL, Habib S., posted in PubMed
2. Diarrhea, caused by the laxative effect of oral use of Aloe Vera
3. oral use of Aloe Vera may cause abdominal cramps and pain
4. It may cause of rheumatoid arthritis symptoms as a result of collagen in the plant, according to the study of "Oral type II collagen in the treatment ofrheumatoid arthritis. A six-month double blind placebo-controlled study" by Cazzola M, Antivalle M, Sarzi-Puttini P, Dell'Acqua D, Panni B, Caruso I., posted in PubMed
5. Etc.


References
(1) Aloe barbadensis Mill. formulation restores lipid profile to normal in a letrozole-induced polycystic ovarian syndrome rat Model (PubMed)
(2) ALOE VERA by Gertrude Baldwin,http://www.herballegacy.com/Baldwin_Chemical.html
(3) Effect of Aloe barbadensis Mill. formulation on Letrozole induced polycystic ovarian syndrome rat model (PubMed)
(4) Effect of a polyphenol-rich extract from Aloe vera gel on experimentally induced insulin resistance in mice (PubMed)
(5) Oral aloe vera-induced hepatitis(PubMed)
(6) Oral type II collagen in the treatment of rheumatoid arthritis. A six-monthdouble blind placebo-controlled study(PubMed)


Herbal Therapy: The Aloe Vera effects on Cancers

Kyle J. Norton(Scholar, Master of Nutrients), all right reserved.
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

                 
                                         Aloe Vera

Aloe Vera is species of succulent plant in the genus Aloe, belonging to the Family Xanthorrhoeaceae, native to Sudan. It has become very popular for commercial cultivation due to its health benefits. Aloe vera has been used in herbal medicine in treating many kinds of disease, including wound, burn healing, minor skin infections, sebaceous cysts, diabetes, and elevated of cholesterol, etc. It is also one of many popular herb studied in scientific ways with some conflicted results.


                                                     Cancers




Cancer is a class of diseases in which a group of cells growing and multiplying disordered and uncontrollable way in our body, have become progressively worse and damaged other healthy tissues, sometimes spreads to other organs in the body via lymph or blood and results may be in death.

The Ingredients
The ten main areas of chemical constituents of Aloe vera include: amino acids, anthraquinones, enzymes, minerals, vitamins, lignins, monosaccharide, polysaccharides, salicylic acid, saponins, and sterols.
They all work together in a synergistic way to create healing and health giving benefits, according to Gertrude Baldwin in the article of THE BENEFITS OF THE USE OF ALOE VERA IN HERBAL PREPARATIONS.

The Benefits
Aloe-Emodi, a chemical compound found in Aloe vera, specifically suppress breast cancer cell proliferation by targeting ER α protein stability through distinct mechanisms and may be used as a possible application of anthraquinones in preventing or treating breast cancer in the future. Also in other study, Aloe-Emodi is considered as a potential value for the treatment of gastric cancer and cervical cancer because of its mechanisms are by means of cell cycle interruption and induce differentiation and suppressed the expression of PKCalpha and c-myc.Radiotherapy are most often used to treat head and neck cancer patients. Ina study of Aloe Vera, Dr. Ahmadi A. found that oral Aloe vera mouthwash may not only prevent radiation-induced mucositis, but also may reduce oral candidiasis of patients undergoing head and neck radiotherapy due to its antifungal and immunomodulatory properties

The Side effects
1. Hepatitis
Some researchers concerned that the over use of oral aloe vera may contribute to acute hepatitis, according to the study of "Oral aloe vera-induced hepatitis" by Bottenberg MM, Wall GC, Harvey RL, Habib S., posted in PubMed
2. Diarrhea, caused by the laxative effect of oral use of Aloe Vera
3. oral use of Aloe Vera may cause abdominal cramps and pain
4. It may cause of rheumatoid arthritis symptoms as a result of collagen in the plant, according to the study of "Oral type II collagen in the treatment ofrheumatoid arthritis. A six-month double blind placebo-controlled study" by Cazzola M, Antivalle M, Sarzi-Puttini P, Dell'Acqua D, Panni B, Caruso I., posted in PubMed
5. Etc.

References
(1) Aloe barbadensis Mill. formulation restores lipid profile to normal in a letrozole-induced polycystic ovarian syndrome rat Model (PubMed)
(2) ALOE VERA by Gertrude Baldwin,http://www.herballegacy.com/Baldwin_Chemical.html
(3) Potential prevention: Aloe vera mouthwash may reduce radiation-induced oral mucositis in head and neck cancer patients. by Ahmadi A.(PubMed)
(4) Emodin and Aloe-Emodin Suppress Breast Cancer Cell Proliferation through ER α Inhibition.
Huang PH, Huang CY, Chen MC, Lee YT, Yue CH, Wang HY, Lin H.(PubMed)
(5) Growth inhibitory effects of gastric cancer cells with an increase in S phase and alkaline phosphatase activity repression by aloe-emodin. by Guo J, Xiao B, Zhang S, Liu D, Liao Y, Sun Q.(PubMed)
(6) Anticancer effect of aloe-emodin on cervical cancer cells involves G2/M arrest and induction of differentiation. by Guo JM, Xiao BX, Liu Q, Zhang S, Liu DH, Gong ZH.(PubMed)
(5) Oral aloe vera-induced hepatitis(PubMed)
(6) Oral type II collagen in the treatment of rheumatoid arthritis. A six-monthdouble blind placebo-controlled study(PubMed)

Monday, September 26, 2016

Herbal Therapy: The Aloe Vera effects on Gastric Ulcers

Kyle J. Norton(Scholar, Master of Nutrients), all right reserved.
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

                 
                                         Aloe Vera

Aloe Vera is species of succulent plant in the genus Aloe, belonging to the Family Xanthorrhoeaceae, native to Sudan. It has become very popular for commercial cultivation due to its health benefits. Aloe vera has been used in herbal medicine in treating many kinds of disease, including wound, burn healing, minor skin infections, sebaceous cysts, diabetes, and elevated of cholesterol, etc. It is also one of many popular herb studied in scientific ways with some conflicted results.


                                                     Gastric Ulcers



Gastric ulcers is defined as a condition of a localized tissue erosion in the liningthe stomach. as a result of bacteria Helicobacter pylori (H pylori) in most cases.

The Ingredients
The ten main areas of chemical constituents of Aloe vera include: amino acids, anthraquinones, enzymes, minerals, vitamins, lignins, monosaccharide, polysaccharides, salicylic acid, saponins, and sterols.
They all work together in a synergistic way to create healing and health giving benefits, according to Gertrude Baldwin in the article of THE BENEFITS OF THE USE OF ALOE VERA IN HERBAL PREPARATIONS.

The benefits
Some people with gastric ulcers may be not experience any symptoms at all, while others may have burning pain, severe nausea, and vomiting. In the comparison of the effects of Aloe vera and sucralfate on gastricmicrocirculatory changes, cytokine levels and gastric ulcer healing, treatment of Aloe vera found to reduce leukocyte adherence and TNF-alpha level, elevate IL-10 level and promote gastric ulcer healing. Because of its Anti-inflammatory effects, treatment of A. vera process the enhancement in leukocyte-endothelium interaction are associated with reduction in TNF-alpha level. Other in the study of acute gastric mucosal lesions induced by 0.6 M HCl and acid outpu, indicated that Aloe vera is endowed with gastric acid anti-secretory activity and could protect the gastric mucosa at low concentrations against injurious agents. Other component of Aloe vera, the Polymer fraction (Avpf; molecular weight cut-off ≥50 kDa; 150 mg/kg body weight, p.o.), reduce 50% of the mRNA expressions of inducible nitric oxide synthase (iNOS) and neuronal nitric oxide synthase (nNOS), according to the study.


The Side effects
1. Hepatitis
Some researchers concerned that the over use of oral aloe vera may contribute to acute hepatitis, according to the study of "Oral aloe vera-induced hepatitis" by Bottenberg MM, Wall GC, Harvey RL, Habib S., posted in PubMed
2. Diarrhea, caused by the laxative effect of oral use of Aloe Vera
3. oral use of Aloe Vera may cause abdominal cramps and pain
4. It may cause of rheumatoid arthritis symptoms as a result of collagen in the plant
5. Etc.

References
(1) Aloe barbadensis Mill. formulation restores lipid profile to normal in a letrozole-induced polycystic ovarian syndrome rat Model (PubMed)
(2) ALOE VERA by Gertrude Baldwin,http://www.herballegacy.com/Baldwin_Chemical.html
(3) Effects of Aloe vera and sucralfate on gastric microcirculatory changes, cytokine levels and gastric ulcer healing in rats, by Eamlamnam K, Patumraj S, Visedopas N, Thong-Ngam D.(PubMed)
(4) Anti-inflammatory effects of Aloe vera on leukocyte-endothelium interaction in the gastric microcirculation of Helicobacter pylori-infected rats by Prabjone R, Thong-Ngam D, Wisedopas N, Chatsuwan T, Patumraj S.(PubMed)
(5) The effect of Aloe vera A. Berger (Liliaceae) on gastric acid secretion and acute gastric mucosal injury in rats by Yusuf S, Agunu A, Diana M.(PubMed)
(6) Polymer fraction of Aloe vera exhibits a protective activity on ethanol-inducedgastric lesions.
Park CH, Nam DY, Son HU, Lee SR, Lee HJ, Heo JC, Cha TY, Baek JH, Lee SH.(PubMed)