Medical Advisor Journals

Thursday, September 29, 2016

Herbal therapy: Popular Herbal Yohimbe Bark

Chinese Food Therapy
The Best Way to prevent, treat your disease, including Obesity
and restore your health naturally with Chinese diet

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Super foods Library, Eat Yourself Healthy With The Best of the Best Nature Has to Offer

Sources
(a) http://www.ncbi.nlm.nih.gov/pubmed/19876857
(1) http://www.tandfonline.com/doi/abs/10.1080/15438620600987106
(2) http://content.karger.com/ProdukteDB/produkte.asp?doi=10.1159/000104877
(3) http://www.ncbi.nlm.nih.gov/pubmed/17945493
(4) http://www.ncbi.nlm.nih.gov/pubmed/14735230
(5) http://www.ncbi.nlm.nih.gov/pubmed/8031688
(6) http://www.ncbi.nlm.nih.gov/pubmed/8836468

Food Therapy: Lean Meats - Lamb

Lean Meats - Lamb

Lamb is the meat from young sheep that are less than one year old. Although they are not consumed much in the North America but it is used in cooking some wonderful recipes throughout the world.

Nutrients
1. Protein
2. B vitamin
3. Folate
4. Fat (Saturated and mono-unsaturated)
5. Zinc
6. Niacin
7. Selenium
8. Phosphorus
9. Iron
10. Etc.

Health Benefits
A. Health benefits according to studies
1. Serum lipid profileIn the investigation of total and saturated fat intake in the management of high blood cholesterol levels for cardiovascular risk found that consumption of lean red meat (lamb) or lean white meat (chicken) as part of the usual diet is associated with a similar lipid response. These two foods can be exchanged in a healthy diet to increase palatability, according to "Effect of lean red meat from lamb v. lean white meat from chicken on the serum lipid profile: a randomised, cross-over study in women" by Mateo-Gallego R, Perez-Calahorra S, Cenarro A, Bea AM, Andres E, Horno J, Ros E, Civeira F.(a)

2. Hypercholesterolemia
In the investigation of intake of all meat, particularly red meat and theirs effect in lowering cholesterol found that Consumption of lean red meat or lean white meat, as part of an NCEP Step I diet, is similarly effective for reducing LDL cholesterol and elevating HDL cholesterol concentrations in free-living persons with hypercholesterolemia, according to "Incorporation of lean red meat into a National Cholesterol Education Program Step I diet: a long-term, randomized clinical trial in free-living persons with hypercholesterolemia" by Hunninghake DB, Maki KC, Kwiterovich PO Jr, Davidson MH, Dicklin MR, Kafonek SD.(b)

3 . Blood pressure
In the research of Low-sodium Dietary Approaches to Stop Hypertension (DASH) diets and its health effect found that a low-sodium DASH diet with a low dietary acid load, which also included lean red meat on most days of the week, was effective in reducing BP in older women, particularly in those taking antihypertensive medications, according to "Low-sodium Dietary Approaches to Stop Hypertension-type diet including lean red meat lowers blood pressure in postmenopausal women" by Nowson CA, Wattanapenpaiboon N, Pachett A.(c)

4. Good Sources of Nutrient
In the investigation of "Lean meat and heart health" found that lean red meatconsumption has no effect on in vivo and ex vivo production of thromboxane and prostacyclin or the activity of haemostatic factors. It is also a good source of protein, omega-3 fatty acids, vitamin B12, niacin, zinc and iron. In conclusion, leanred meat, trimmed of visible fat, which is consumed in a diet low in saturated fat does not increase cardiovascular risk factors (plasma cholesterol levels or thrombotic risk factors), according to "Lean meat and heart health" by Li D, Siriamornpun S, Wahlqvist ML, Mann NJ, Sinclair AJ.(d)

5. Lean meat and over all health
In the observation of Dietary lean red meat and human evolution found that leanmeat is a healthy and beneficial component of any well-balanced diet as long as it is fat trimmed and consumed as part of a varied diet, according to "Dietary leanred meat and human evolution" by Mann N.(e)

6. Etc.

B. Health benefits according to concentration
1. Tryptophan
Tryptophan is one of the 10 essential amino acids which the body uses to synthesize the proteins for brain cells need, thus enhancing the nerve cells in information transmitting between themselves and cells in the parts of the body that reduces the risk of anxiety and depression, according to the study of "The effects of tryptophan depletion on neural responses to emotional words in remitted depression" by Roiser JP, Levy J, Fromm SJ, Nugent AC, Talagala SL, Hasler G, Henn FA, Sahakian BJ, Drevets WC.(I)

2. Protein
In the research of the importance of dietary proteins influence body weight by affecting four targets for body weight regulation: satiety, thermogenesis, energy efficiency, and body composition, found that Ingestion of dietary proteins in diabetes type 1 exerts a delayed postprandial increase in blood glucose levels due to protein-induced stimulation of pancreatic glucagon secretion. Higher than minimal amounts of protein in the diet needed for nitrogen balance may play animportant role for the increasing number of elderly obese subjects in our industrialized societies, since proteins exert beneficial effects in the conditions of overweight, metabolic syndrome, cardiovascular risk factors, bone health, and sarcopenia. Adverse effects of increased dietary proteins have been observed in subjects with renal impairment- this problem is frequently observed in the elderly, hypertensive, and diabetic population. Nevertheless, dietary proteins deserve more attention than they have received in the past, according to "Dietary proteins in obesity and in diabetes" by Keller U.(II)

3. Selenium
Lamp contains trace minerals selenium which is essential for the healthy function of the thyroid and immune system as it increases the antioxidant defense system by fighting against the forming of free radicals and reduce the risk of irregular cells growth causes of tumor and cancer, according to the study of "Selenium in theimmune system" by Arthur JR, McKenzie RC, Beckett GJ., posted in PubMed (http://www.ncbi.nlm.nih.gov/pubmed/12730442)

4. Vitamin B12
Besides supporting the production of red blood cell and maintaining the proper duplication of DNA, the genetic material in all cells, according to the study of "Vitamin B 12 and the macromolecular composition of Euglena. II. Recovery from unbalanced growth induced by Vitamin B 12 deficiency" by Johnston PL, Carell EF., posted in PubMed (http://www.ncbi.nlm.nih.gov/pubmed/4633443), it also plays an important role in promoting neurite outgrowth, according to the study of "Akt/mammalian target of rapamycin signaling pathway regulates neurite outgrowth in cerebellar granule neurons stimulated by methylcobalamin" by Okada K, Tanaka H, Temporin K, Okamoto M, Kuroda Y, Moritomo H, Murase T, Yoshikawa H., posted in PuBmed (http://www.ncbi.nlm.nih.gov/pubmed/21458538)

5. Vitamin B3
Vitamin B3 or Niacin is essential for lowering high cholesterol levels, according to the study of "Cholesterol efflux potential and antiinflammatory properties of high-density lipoprotein after treatment with niacin or anacetrapib" by Yvan-Charvet L, Kling J, Pagler T, Li H, Hubbard B, Fisher T, Sparrow CP, Taggart AK, Tall AR., posted in PubMed (http://www.ncbi.nlm.nih.gov/pubmed/20448206), forming the components of cells' genetic material DNA during excision repair, according to the study of "Niacin deficiency delays DNA excision repair and increases spontaneous and nitrosourea-induced chromosomal instability in rat bone marrow" by
Kostecki LM, Thomas M, Linford G, Lizotte M, Toxopeus L, Bartleman AP, Kirkland JB., posted in PubMed (http://www.ncbi.nlm.nih.gov/pubmed/17618655) and treating diabetes and high blood sugar levels, according to the study of "Treatment of dyslipidemia in patients with type 2 diabetes" by Vijayaraghavan K., posted in PubMed (http://www.ncbi.nlm.nih.gov/pubmed/21172030), researcher indicated that a number of lipid-lowering agents, including statins, fibrates, niacin, and bile acid sequestrants, are available to target normalization of the entire lipid profile.

6. Etc.

C. Other health benefits
1. Zinc
Zinc beside promote healthy immune system in fighting against the forming of free radical and guarding our body from infection and inflammation due to foreign invasion, according to the study of "Essential role of vitamin C and zinc in child immunity and health" by Maggini S, Wenzlaff S, Hornig D., posted in PubMed (1) it is also an essential trace mineral for prostate health in assisting the male reproduction system to maintain healthy sperm production and against prostate cancer, according to the study of "The role of survivin and Bcl-2 inzinc-induced apoptosis in prostate cancer cells" by Ku JH, Seo SY, Kwak C, Kim HH., posted in PubMed(2).

2. Weigh loss
High levels of protein only is necessary for the body growth, according to the study of "A high-protein diet with resistance exercise training improves weight lossand body composition in overweight and obese patients with type 2 diabetes" by Wycherley TP, Noakes M, Clifton PM, Cleanthous X, Keogh JB, Brinkworth GD., posted in pubMed(3) but also helps you feel satisfied longer, thus preventing the weigh gain.

3. Iron
Iron is one of important mineral in forming complexes with molecular oxygen in hemoglobin, according to the study of "Glutathionyl Hemoglobin Is Elevated inIron Deficiency Anemia" by Shet AS, Pinto SM, Mitra G, Mandal AK., posted in PubMed(4), thus helping to carry oxygen to the muscles for energy and enhancing the brain performance, including memory and concentration.

5. Mono-unsaturated fat
Lamb contains mono-unsaturated fat, that helps to reduce the risk of bad cholesterol accumulation in the blood stream, causing hypertension and heart diseases and stroke., according to the study of "Dietary fats and oils: technologies for improving cardiovascular health" by Flickinger BD, Huth PJ., posted in PubMed(5)

6. Etc.

Side Effects
1. Saturated fat may cause clotting up of the arteries and vein.
2. Purines in lamp can cause the forming of kidney stone and problem for certain people.
3. Etc.

Chinese Food Therapy
The Best Way to prevent, treat your disease, including Obesity
and restore your health naturally with Chinese diet

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Super foods Library, Eat Yourself Healthy With The Best of the Best Nature Has to Offer

Sources
(a) http://www.ncbi.nlm.nih.gov/pubmed/21902857
(b) http://www.ncbi.nlm.nih.gov/pubmed/10872897
(c) http://www.ncbi.nlm.nih.gov/pubmed/19185772
(d) http://www.ncbi.nlm.nih.gov/pubmed/15927927
(e) http://www.ncbi.nlm.nih.gov/pubmed/10918988

(I) http://www.ncbi.nlm.nih.gov/pubmed/19539268
(II) http://www.ncbi.nlm.nih.gov/pubmed/22139563

(1) http://www.ncbi.nlm.nih.gov/pubmed/20515554
(2) http://www.ncbi.nlm.nih.gov/pubmed/20822926
(3) http://www.ncbi.nlm.nih.gov/pubmed/20150293(4)http://www.ncbi.nlm.nih.gov/pubmed/21996674
(5) http://www.ncbi.nlm.nih.gov/pubmed/15485593

Food Therapy: Poultry and Lean Meats - Chicken (Gallus gallus domesticus)

Chicken (Gallus gallus domesticus)

Chicken are domesticated fowl belonging to the subspecies of Gallus domesticus and is raised all over the world for its delicious meats and eggs. It can be roasted, broiled, grilled or poached into a very delicious, tasteful and nutritious meal.

Nutrients
In order to prevent the high levels in take of saturated fat (bad cholesterol), it is recommended to remove the skin before cooking.
1. Proteins
2. Cholesterol (LDL and HDL)
3. Vitamin B3
4. Vitamin B6
5. Selenium
6. Phosphorus
7. Iron
8.Choline
9. Etc.

Health benefits
A. Health benefits according to studies
1. Vitamins and minerals
In the classification of protein hydrolysates. Calcium, phosphorus and iron were analyzed by inductively coupled-plasma atomic emission spectrophotometry; vitamin C was analyzed by the reduction of cupric ions and vitamins B1 and B2 by fluorescence in beef, chicken, and turkey found that the beef hydrolysate (BH) had more iron than the turkey hydrolysate (TH) and the chicken hydrolysate (CH); TH had a little more phosphorus. BH had the largest amount of vitamin C, and similar amounts of vitamins B1 and B2. The amount of these nutrients found in the hydrolysates suggests that it is possible to use them to enrich special dietary formulations, according to "Mineral and vitamin content of beef, chicken, and turkey hydrolysates mineral and vitamin content of protein hydrolysates" by Maria Elisabeth Machado Pinto e SilvaI, Ive PatonI, Marlene TrigoI; Maria Carolina B. C. von AtzingenI, Carmem S. KiraII, Emiko I. InomataII, Leda C. A. LamardoII(a)

2. Hypercholesterolemia
In the research of the contribution of beef, pork, lamb, and veal to total fat, saturated fat, and cholesterol intake from a total-diet standpoint found that Substituting skinless chicken or fish for meat may make sense from the standpoint of personal preference and dietary variety but does not confer additional benefits in terms of reducing blood cholesterol levels, according to "Hypercholesterolemia. Dietary advice for patients regarding meat" by Keenan JM, Morris DH.(b)

3. Iron and zinc
In the evaluation of Reducing red meat intake to lower serum cholesterol may also lower iron and zinc intake found that although serum ferritin level change between baseline and intervention was significantly different between the lean beef and lean poultry and fish groups (median [interquartile range] 0.7 [-6, 8] and -6.8 [-12, 2] microg/dL, respectively), the drop in the lean poultry and fish group was not clinically significant. No differences were observed in iron and zinc intake or in serum zinc and cholesterol levels. Teenagers eating diets low in saturated fat may benefit from adequate amounts of lean red meat, according to "Adolescents eating diets rich in either lean beef or lean poultry and fish reduced fat and saturated fat intake and those eating beef maintained serum ferritin status" by Snetselaar L, Stumbo P, Chenard C, Ahrens L, Smith K, Zimmerman B.(c)

4. Nutrients
In the investigation of food selection of the healthy elderly may be influenced by life-styles, the food supply, and recommendations related to diet and disease found that a moderate but not excessive intake of meat/poultry/fish made a substantial contribution to nutrient intake. The fat contribution of these food groups could be decreased by emphasizing lower-fat selections of meat, poultry, and fish, according to "Meat, poultry, and fish consumption and nutrient intake in the healthy elderly" by Koehler KM, Hunt WC, Garry PJ.(d)

5. Etc.

B. Health benefits according to concentration
1. Vitamin B complex

a) Vitamin B2 or Riboflavin is one of very important vitamin in metabolism of energy by helping the transforming of fats, proteins and carbohydrates and high dose riboflavin appears to be useful alone or along with beta-blockers in the prevention of migraine, according to the study of "Effectiveness of high-doseriboflavin in migraine prophylaxis. A randomized controlled trial" by Schoenen J, Jacquy J, Lenaerts M., posted in PubMed (http://www.ncbi.nlm.nih.gov/pubmed/9484373)

b) Vitamin B3
Vitamin B3 or Niacin is essential for lowering high cholesterol levels, according to the study of "Cholesterol efflux potential and antiinflammatory properties of high-density lipoprotein after treatment with niacin or anacetrapib" by Yvan-Charvet L, Kling J, Pagler T, Li H, Hubbard B, Fisher T, Sparrow CP, Taggart AK, Tall AR., posted in PubMed (http://www.ncbi.nlm.nih.gov/pubmed/20448206), forming the components of cells' genetic material DNA during excision repair, according to the study of "Niacin deficiency delays DNA excision repair and increases spontaneous and nitrosourea-induced chromosomal instability in rat bone marrow" by

Kostecki LM, Thomas M, Linford G, Lizotte M, Toxopeus L, Bartleman AP, Kirkland JB., posted in PubMed (http://www.ncbi.nlm.nih.gov/pubmed/17618655) and treating diabetes and high blood sugar levels, according to the study of "Treatment of dyslipidemia in patients with type 2 diabetes" by Vijayaraghavan K., posted in PubMed (http://www.ncbi.nlm.nih.gov/pubmed/21172030), researcher indicated that a number of lipid-lowering agents, including statins, fibrates, niacin, and bile acid sequestrants, are available to target normalization of the entire lipid profile.

c) Vitamin B6
c. 1. Vitamin B6 or Pyridoxine beside is important in enhancing the developing red blood cells by stimulating the production of hemoglobin, it also helps to keep blood sugar levels steady during the process of breaking down stored energy in gestation pregnancy, according to the study of "Improvement of oral glucose tolerance in gestational diabetes by pyridoxine" by Bennink HJ, Schreurs WH., posted in PubMed (http://www.ncbi.nlm.nih.gov/pubmed/1131652)

c.2. It also plays a pivotal role as a methyl donor in the basic cellular process ofmethylation, through which methyl groups are transferred from one molecule to another, resulting in the formation of a wide variety of precess, including regulation of gene expression, protein function, and RNA metabolism. When levels of B6 are inadequate, it may cause faulty Methylation with high levels of homocysteine that can cause variety of disease, including cervical dysplasia, faulty detoxification and impaired DNA repair, etc., according to the study of "Back To Life Natural Health Center - Healthcare Through Natural Methods"(http://www.backtolifehealth.com/Methylation.htm)

d) Vitamin B12In the evaluation of vitamin B12 in Turnip greens found that vitamin Bi2 was present in the
leaves of a higher plant in amounts. there is no evidence supporting the synthesis of vitamin Bi2 by a higher plant. Was it produced by soil microorganisms and subsequently absorbed via the plant roots? There is ample proof of such synthetic activity by certain microorganisms and of vitamin B12 activity in soil , but no evidence that the vitamin B]2molecule is absorbed by the plant from the soil. Could it have been produced by bacteria living epiphytically
on the turnip leaf? Ericson and Lewis ('54) postulated such a relationship in their studies of vitamin Bt2 compounds found in certain algae, according to "STUDIES OF VITAMIN B12IN TUENIP GREENS" by LOUISE F. GEAY ANDLOUISE J. DANIEL(http://jn.nutrition.org/content/67/4/623.full.pdf)

2. Protein
Protein beside is important building block of bones, muscles, cartilage, skin, and blood, it also enhances the nervous system in information transmitting between cells and cells of the other parts of the body, thus reducing the risk of nervous tension, (according to the study of "The planar polarity protein Scribble1 is essential for neuronal plasticity and brain function" by Moreau MM, Piguel N, Papouin T, Koehl M, Durand CM, Rubio ME, Loll F, Richard EM, Mazzocco C, Racca C, Oliet SH, Abrous DN, Montcouquiol M, Sans N, posted in PubMed (http://www.ncbi.nlm.nih.gov/pubmed/20660256)

3. Iron
Beside as a mineral in carrying life-giving oxygen to human blood cells and maintaining robust health as an essential protein component for metabolism, it also helps in synthesis of a number of essential neurotransmitters like dopamine, nor-epinephrine, along with serotonin. acccording to the study of "Brain Iron Dysregulation and the Risk of Ageing White Matter Lesions" by Gebril OH, Simpson JE, Kirby J, Brayne C, Ince PG., posted in PubMed, researchers found that The mRNA expression using QPCR suggests a pattern that favours decreased intracellular iron influx, increased ferrous oxidation and increased iron export from the cells. Iron metabolism seems to be changed in brains with WML, increased elemental iron in these brains and in turn increased production of free oxidative radicals could represent a potentiating factor for the development of ageing WML.

4. Selenium
In the investigation of genistin and selenium and their effect in breast cancer found that Supplementation of genistin alone or with selenium provided antioxidant defense with high-potential chemopreventive activity against DMBA-induced mammary tumors more than selenium alone, according to "Prevention of rat breast cancer by genistin and selenium" by Hamdy SM, Latif AK, Drees EA, Soliman SM.(I)

5. phosphorus
Phosphorus is one of essential trace minerals to maintains healthy teeth and bones, according to the study of "Phosphorus nutrition and the treatment ofosteoporosis" by Heaney RP, posted in PubMed (II).

6. Calcium
In the investigation of micronutrients, calcium (Ca) and inorganic (i) phosphate (P) ,the two main constituents of hydroxyapatite and theirs effect on bone health found that they are endowed with a transport system that accumulates Pi inside the matrix vesicles, followed by the influx of Ca ions. This process leads to the formation of hydroxyapatite crystal and its subsequent association with the organic matrix collagen fibrils. In addition to this structural role, both Ca and Pi positively influence the activity of bone-forming and bone-resorbing cells. Pi plays a role in the maturation of osteocytes, the most abundant cells in bone. Osteocytes are implicated in bone mineralization and systemic Pi homeostasis, according to"Calcium and phosphate: a duet of ions playing for bone health" by Bonjour JP.(III)

7. Etc.

C. Other health benefits
1. Cholesterol
The chicken of skin contains about 50 - 50 good and bad cholesterol. We know that cholesterol good or bad are necessary for keeping good health for all the cells in the body, including brain cells, according to the study of "Liposome formulated with TAT-modified cholesterol for improving brain delivery and therapeutic efficacy on brain glioma in animals" by Qin Y, Chen H, Zhang Q, Wang X, Yuan W, Kuai R, Tang J, Zhang L, Zhang Z, Zhang Q, Liu J, He Q., posted in PubMed(1) Too much of bad cholesterol can cause clotting up the arteries and veins and hardening the arterial walls, leading to break off or blocking the flow, causing heart disease and stroke, according to the study of "Dietary fat and cholesterol and risk ofcardiovascular disease in older adults: the Health ABC Study" by Houston DK, Ding J, Lee JS, Garcia M, Kanaya AM, Tylavsky FA, Newman AB, Visser M, Kritchevsky SB; Health ABC Study, posted in PubMed(2). It is advised that people with high levels of bad cholesterol should avoid to eat chicken and replace it with plant base cholesterol.

2. Reduce the risk of cancer
B vitamin- niacin is important component of the enzyme systems that repair broken DNA molecules. Deficiency of niacin can cause genetic DNA damage, leading to cancer, according to the study of "Niacin deficiency and cancer in women" by Jacobson EL., posted in PubMed(3), the researchers wrote that Studies of the consequences of DNA damage in cultured mouse and human cells as a function of niacin status have supported the hypothesis that niacin may be a protective factor that limits carcinogenic events.

3. Antioxidant
Since it contain high levels of selenium which the essential trace minerals necessary for the major metabolic pathways and immune system in fighting against the forming of free radicals and prevent the invasion of foreign virus and bacteria, causing irregular cells growth, infection and inflammation, according to the study of "Selenium in the immune system" by Arthur JR, McKenzie RC, Beckett GJ., posted in PubMed(4)

5. Collagen
Collagen from the chicken leg, a fibrous protein, is used to connect and support other body tissues, has an ability to act as an ACE inhibitor in reducing blood pressure in people with hypertension, acording to the study of "Therapeutic effects of marine collagen peptides on Chinese patients with type 2 diabetes mellitus and primary hypertension" by Zhu CF, Li GZ, Peng HB, Zhang F, Chen Y, Li Y, posted in PubMed(5), researchers wrote that MCPs(Marine collagenpeptides) supplement may benefit glucose and lipid metabolism, insulin sensitivity, renal function and hypertension management in Chinese patients with T2DM andhypertension
6. Etc.

Side Effects
1. Increases the risk of heart attack and stoke, due to bad cholesterol.
2. Purines in all meat, including chicken can cause health problems in some individuals due to excess of uric acid.
3. Etc.
Chinese Food Therapy
The Best Way to prevent, treat your disease, including Obesity
and restore your health naturally with Chinese diet

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Super foods Library, Eat Yourself Healthy With The Best of the Best Nature Has to Offer

Herbal therapy: Popular Herbal Yarrow (Achillea millefolium)

Kyle J. Norton(Scholar and Master of Nutrients, all right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

Tea Tree oil

Yarrow is a flowering plant in the genus Achillea, belonging to the family Asteraceae, native to the Northern Hemisphere. The herb has been used in traditional medicine as astringent, antiseptic and anti-inflammatory, antispasmodics agent to promote healing of cuts and wounds, burns and ulcers, skin diseases, digestive disorders, treat menstrual irregularity, relieve menstrual cramps and pain, etc.

Health benefits
1. Hyperactive cardiovascular and airway disorders
In the investigation of the crude extract of Achillea millefolium (Am.Cr) and its hypotensive, cardio-depressant, vasodilatory and bronchodilatory activities, found that Achillea millefolium exhibits hypotensive, cardiovascular inhibitory and bronchodilatory effects, thus explaining its medicinal use in hyperactive cardiovascular and airway disorders, such as hypertension and asthma, according to "Blood pressure lowering, cardiovascular inhibitory and bronchodilatory actions of Achillea millefolium" by Khan AU, Gilani AH.(1)

2. Gastroprotective effect
In the evaluation of the efficacy of a hydroalcoholic extract from the Achillea millefolium (HE) for gastroprotective properties and additional mechanism(s) involved in this activity, found that Oral administration of HE (30, 100 and 300mg/kg) inhibited ethanol-induced gastric lesions by 35, 56 and 81%, respectively. Oral treatment with HE (1 and 10mg/kg) reduced the chronic gastric ulcers induced by acetic acid by 43 and 65%, respectively, and promoted significant regeneration of the gastric mucosa after ulcer induction denoting increased cell proliferation, which was confirmed by PCNA immunohistochemistry. HE treatment prevented the reduction of GSH levels and SOD activity after acetic acid-induced gastric lesions. In addition, HE (10mg/kg) inhibited the MPO activity in acetic acid-induced gastric ulcers, according to "Antiulcerogenic activity of hydroalcoholic extract of Achillea millefolium L.: involvement of the antioxidant system" by Potrich FB, Allemand A, da Silva LM, Dos Santos AC, Baggio CH, Freitas CS, Mendes DA, Andre E, Werner MF, Marques MC.(2)

3. Anxiolytic-like effects
In the evaluation of the potential anxiolytic-like effect of hydroalcoholic extract of Achillea millefolium L. in animal models, found that The results indicate that the orally administered hydroalcoholic extract of Achillea millefolium L. exerted anxiolytic-like effects that likely were not mediated by GABA(A)/BDZ neurotransmission and did not present tolerance after short-term, repeated administration, according to "Anxiolytic-like effects of acute and chronic treatment with Achillea millefolium L. extract" by Baretta IP, Felizardo RA, Bimbato VF, Santos MG, Kassuya CA, Gasparotto Junior A, da Silva CR, de Oliveira SM, Ferreira J, Andreatini R.(3)

4. Prokinetic effect
In the investigaion of the effect of a standardized dry water extract obtained from A. millefolium flowering tops (AME) on gastric motility, found that (i) AME exerts a direct spasmogenic effect on gastric antrum; (ii) choline is the chemical ingredient responsible of such effect; (iii) the prokinetic effect of AME observed in vivo could provide the pharmacological basis underlying its traditional use in the treatment of dyspepsia, according to "Prokinetic effect of a standardized yarrow (Achillea millefolium) extract and its constituent choline: studies in the mouse and human stomach" by Borrelli F, Romano B, Fasolino I, Tagliatatela-Scafati O, Aprea G, Capasso R, Capasso F, Coppola Bottazzi E, Izzo AA.(4)

5. Antiproliferative activity
In the determination of Achillinin A (2β,3β-epoxy-1α,4β,10α-trihydroxyguai-11(13)-en-12,6α-olide, 1), a new guaianolide isolated from the flower of Achillea millefolium, found that the new isolation exhibited potential antiproliferative activity to A549, RERF-LC-kj and QG-90 cells with 50% inhibitory concentration (IC(50)) values of 5.8, 10 and 0.31 µM, respectively, according to "Achillinin A, a cytotoxic guaianolide from the flower of Yarrow, Achillea millefolium" by Li Y, Zhang ML, Cong B, Wang SM, Dong M, Sauriol F, Huo CH, Shi QW, Gu YC, Kiyota H.(5)

6. Anti leukemia
In the examination of three new antitumor sesquiterpenoids, achimillic acids A, B and C, were isolated as methyl esters from Achillea millefolium found that The compounds were found to be active against mouse P-388 leukemia cells in vivo, according to "Novel antitumor sesquiterpenoids in Achillea millefolium' by Tozyo T, Yoshimura Y, Sakurai K, Uchida N, Takeda Y, Nakai H, Ishii H.(6)

7. Anti aging effect
In the evaluation of evaluate the effect of A. millefolium extract on the expression pattern of various epidermal differentiation markers ex vivo in normal human skin biopsies using quantitative image analysis and its capacity to rejuvenate the appearance of skin surface in vivo.
found that millefolium extract at 2% significantly improved the appearance of wrinkles and pores compared with placebo. Results were also directionally better than those of glycolic acid that was chosen as reference resurfacing molecule, according to "Surface rejuvenating effect of Achillea millefolium extract" by Pain S, Altobelli C, Boher A, Cittadini L, Favre-Mercuret M, Gaillard C, Sohm B, Vogelgesang B, André-Frei V.(7)

8. Vascular inflammation
In the investigation of the effects of Achillea millefolium extract in vitro on the growth of primary rat vascular smooth muscle cells (VSMCs) as well as the potential involvement of estrogen receptors (ERs) in this process, indicated that our findings support some of the traditional uses of A. millefolium, and suggest potential modes of action as related to its effects on vascular inflammation. Therefore, A. millefolium may induce novel potential actions in the cardiovascular system, according to "Vasoprotective activity of standardized Achillea millefolium extract" by Dall'Acqua S, Bolego C, Cignarella A, Gaion RM, Innocenti G.(8)

9. Spermatogenesis
In the investigationof the effects of A. millefolium L. extract on spermatogenesis in adult male wistar rats found that a significant decrease in cell accumulation and vacuolization in seminiferous tubule was seen. At the dose of 800 mg/kg, IP, thickened seminiferous tubules on basal membrane, decrease in cell accumulation in seminiferous tubule, severe disarrangement, degenerative cells and severe decrease in sperm count were seen. At the dose of 800 mg/kg/day, orally, basal membrane was thickened and the disarrangement in cells was demonstrated. As a conclusion, our results suggest that the total extract of A. millefolium L. exhibit temporary antifertile activity in adult male animals, according to "The effect of Achillea millefolium extract on spermatogenesis of male Wistar rats" by Takzare N, Hosseini MJ, Hamideh Mortazavi S, Safaie S, Moradi R.(9)

10. Anti-inflammatory activity
In the examination of the crude plant extract in in vitro-protease inhibition assays for understanding the mechanisms of anti-inflammatory action, found that in vitro-antiphlogistic activity of Achillea is at least partly mediated by inhibition of HNE and MMP-2 and -9. After the recently described spasmolytic and choleretic effects the obtained results give further insights into the pharmacological activity ofAchillea and confirm the traditional application as antiphlogistic drug, according to "Achillea millefolium L. s.l. -- is the anti-inflammatory activity mediated by protease inhibition?" by Benedek B, Kopp B, Melzig MF.(10)

11. Antioxidants
In the investigation of the antioxidant activity of methanolic and water extracts of Slovene accessions of four medicinal plant species (Salvia officinalis, Achillea millefolium, Origanum vulgare subsp. vulgare and Gentiana lutea), found that . Treatment of the immobilized cells with the plant extracts resulted in an increase of the cell membrane potential (membrane hyperpolarization), possibly due to the reduction of membrane damage due to oxidation. The novel cell biosensor could be utilized as a rapid, high throughput tool for screening the antioxidant properties of plant-derived compounds, according to "Evaluation of the antioxidantsactivities of four Slovene medicinal plant species by traditional and novel biosensory assays" by Kintzios S, Papageorgiou K, Yiakoumettis I, Baricevic D, Kusar A.(11)

12. Antioxidant and Anti microbial activities
In the assessment, in vitro the antimicrobial and antioxidant activities of the essential oil and methanol extracts of Achillea millefolium subsp. millefoliumAfan., found that the oil strongly reduced the diphenylpicrylhydrazyl radical (IC(50)=1.56 micro g/ml) and exhibited hydroxyl radical scavenging effect in the Fe(3+)-EDTA-H(2)O(2) deoxyribose system (IC(50)=2.7 micro g/ml). It also inhibited the nonenzymatic lipid peroxidation of rat liver homogenate (IC(50)=13.5 micro g/ml). The polar phase of the extract showed antioxidant activity. The oil showed antimicrobial activity against Streptococcus pneumoniae, Clostridium perfringens, Candida albicans, Mycobacterium smegmatis, Acinetobacter lwoffii and Candida krusei while water-insoluble parts of the methanolic extracts exhibited slight or no activity, according to "Antioxidant and antimicrobial activity of the essential oil and methanol extracts of Achillea millefolium subsp.millefolium Afan. (Asteraceae)" by Candan F, Unlu M, Tepe B, Daferera D, Polissiou M, Sökmen A, Akpulat HA(12)

13. Etc.

Side effect
1. Overdoses can cause gastrointestinal discofort and excessive urination
2. It can cause allergic effect such as skin rash and irritation. etc.
3. Do not use the herb in new born, children, or if you are pregnant or breast feeding without approval from the related field specialist
4. Etc.

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Herbal therapy: Popular Herbal Valerian

Kyle J. Norton(Scholar and Master of Nutrients, all right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

Valerian

Valerian is a perennial flowering plant, in the genus Valeriana, belonging to the family Valerianaceae, native to Europe and parts of Asia. The herb has been used as a sedative and relaxing agent and to treat the liver, the urinary tract, the digestive tract problem, nerve conditions, etc.

Health Benefits
1. Insomnia
In the investigation of the extracts of the roots of valerian (Valeriana officinalis) used for inducing sleep and improving sleep quality, found that valerian might improve sleep quality without producing side effects. Future studies should assess a range of doses of standardized preparations of valerian and include standard measures of sleep quality and safety, according to " Valerian for sleep: a systematic review and meta-analysis" by Bent S, Padula A, Moore D, Patterson M, Mehling W.(1)

2. Anxiety
In a controlled pilot study on the putative anxiolytic effect of valepotriates, found that the valepotriates may have a potential anxiolytic effect on the psychic symptoms of anxiety. However, since the number of subjects per group was very small, the present results must be viewed as preliminary. Thus, further studies addressing this issue are warranted, according to "Effect of valepotriates (valerian extract) in generalized anxiety disorder: a randomized placebo-controlled pilot study" by Andreatini R, Sartori VA, Seabra ML, Leite JR.(2)

3. Central nervous systemIn the identification of Humans consume a wide range of foods, drugs, and dietary supplements that are derived from plants and which modify the functioning of the central nervous sytem (CNS), indicated that the current evidence for the efficacy of a range of readily available plant-based extracts and chemicals that may improve brain function and which have attracted sufficient research in this regard to reach a conclusion as to their potential effectiveness as nootropics. Many of these candidate phytochemicals/extracts can be grouped by the chemical nature of their potentially active secondary metabolite constituents into alkaloids (caffeine, nicotine), terpenes (ginkgo, ginseng, valerian, Melissa officinalis, sage), and phenolic compounds (curcumin, resveratrol, epigallocatechin-3-gallate, Hypericum perforatum, soy isoflavones), according to "Herbal extracts and phytochemicals: plant secondary metabolites and the enhancement of human brain function" by Kennedy DO, Wightman EL.(3)

4. Antidepressant effect
In the investigation of the antidepressant effect of dichloromethane extract of Valeriana wallichii patchouli alcohol chemotype, found that The extractdemonstrated antidepressant effect and significantly increased the norepinephrine and dopamine levels in forebrain, according to "Antidepressant effect of Valeriana wallichii patchouli alcohol chemotype in mice: Behavioural and biochemical evidence" by Sah SP, Mathela CS, Chopra K.(4)

5. Liver cirrhosis
In the study of the therapeutic effect of the extract of Valeriana jatamansi (family, Valerianaceae) prepared from the dried rhizome of the herb in an animal model of liver cirrhosis and on cell proliferation found that Treatment was found to partially reverse the elevated levels of alkaline phosphatase, γ-glutamyl transferase and selected biochemical markers of hepatic injury including drug-metabolizing enzymes. Histopathology of the hepatic tissue confirmed the therapeutic effect of the extract which corroborated with the biochemical changes. The extract is also reported to ameliorate hepatic cell proliferation in rats injected with thioacetamide. The study has implications in finding a treatment for liver cirrhosis in humans, according to "Valeriana jatamansi partially reverses liver cirrhosis and tissue hyperproliferative response in rat" by Prasad R, Naime M, Routray I, Mahmood A, Khan F, Ali S.(5)

6. Peripheral analgesic effects
In the evaluation of the effect of V. wallichii chemotype (patchouli alcohol) extract(DCME) and essential oil (VPAEO) on experimental models of nociception and to elucidate its possible mechanism of action, found that DCME and VPAEO (40 and 80 mg/kg, p.o.) significantly inhibited the number of writhings as compared to vehicle treated group. None of the doses of DCME and VPAEO exhibited any effect in tail flick model suggesting only peripheral analgesic activity. When studied for mechanism of action in acetic acid induced writhing, subeffective dose of essential oil significantly potentiated the effect of aspirin while no potentiation was seen in case of extract. These data suggest that essential oil VPAEO exerted peripheral analgesic via inhibition of prostaglandin synthesis, accoridng to "Elucidation of possible mechanism of analgesic action of Valeriana wallichii DC chemotype (patchouli alcohol) in experimental animal models" by Sah SP, Mathela CS, Chopra K.(6)

7. Alzheimer's disease
In the investigation of the effects of Valeriana amurensis on the expressions of P-APP,A4,1 and Caspase-3 of cortical neurons and hippocampus neurons in in Alzheimer's disease model rats' brain, found that The 50% ethanol extracts of macroporous resin group from the roots and rhizomes of Valeriana amurensis can decrease the expressions of beta-APP, Abeta(1-40), and Caspase-3, to inhibit the formation of senile plaques and neurofibrillary tangles in Alzheimer's disease model rats' brain, and decrease cell fate of cortical neurons and hippocampus neurons in in Alzheimer's disease model rats' brain, according to "[Effects of Valeriana amurensis on the expressions of beta-APP, Abeta(1-40) and caspase-3 in Alzheimer's disease model rat's brain].[Article in Chinese]" by Zuo YM, Zhang ZL, Wang QH, Xie N, Kuang HX.(7)

8. Antioxidant activity
In the classification of V. officinalis extracts and its antioxidant properties against iron in hippocampal neurons in vitro, found that The effect of V. officinalis in deoxyribose degradation and reactive oxygen species (ROS) production was also investigated. In brain homogenates, V. officinalis inhibited thiobarbituric acid reactive substances induced by all pro-oxidants tested in a concentration dependent manner. Similarly, V. officinalis caused a significant decrease on the LPO in cerebral cortex and in deoxyribose degradation. QA-induced ROS production in cortical slices was also significantly reduced by V. officinalis, according to "In vitro antioxidant activity of Valeriana officinalis against different neurotoxic agents" by Sudati JH, Fachinetto R, Pereira RP, Boligon AA, Athayde ML, Soares FA, de Vargas Barbosa NB, Rocha JB.(8)

9. Anticonvulsant effect
In the study the effect of valerian extracts on an experimental model of temporal lobe epilepsy (TLE), the results showed significant anticonvulsant effect for aqueous but not PE extract of valerian. Moreover, CPT as a selective adenosine A(1) receptor antagonist decreased the anticonvulsant effect of valerian aqueousextract, according to " Anticonvulsant effect of aqueous extract of Valeriana officinalis in amygdala-kindled rats: possible involvement of adenosine" by Rezvani ME, Roohbakhsh A, Allahtavakoli M, Shamsizadeh A.(9)

10. Relaxing effects
In the investigation of the relaxing effects of Valeriana officinalis L. (Valerianaceae) on human uterine muscle found that valerian extracts and valepotriates inhibited uterine contractility in a concentration-dependent manner. Pretreatment with either atenolol or indometacin did not affect the uterine responses to valerian extracts.Valerian extract reduced the maximal contractile response induced by acetylcholine, phenylephrine and histamine independent of the stimulus, according to "Relaxing effects of Valeriana officinalis extracts on isolated human non-pregnant uterine muscle" by Occhiuto F, Pino A, Palumbo DR, Samperi S, De Pasquale R, Sturlese E, Circosta C.(10)

11. Etc.

Side effects
1. Do not use the herb in Newborn, children or if you are pregnant or breast feeding without approval from the related field specialist
2. Valerian may interact with other medicine, including drugs suppress the central nervous system and include Valium, Xanax, Klonopin, Libruim, etc.
3. Etc.

Pregnancy Miracle
Reverse Infertility And Get Pregnant Naturally
Using Holistic Ancient Chinese Medicine

Sources
(1) http://www.ncbi.nlm.nih.gov/pubmed/17145239
(2) http://www.ncbi.nlm.nih.gov/pubmed/12410546
(3) http://www.ncbi.nlm.nih.gov/pubmed/22211188
(4) http://www.ncbi.nlm.nih.gov/pubmed/21354297
(5) http://www.ncbi.nlm.nih.gov/pubmed/21225006
(6) http://www.ncbi.nlm.nih.gov/pubmed/21046983
(7) http://www.ncbi.nlm.nih.gov/pubmed/20575418
(8) http://www.ncbi.nlm.nih.gov/pubmed/19191025
(9) http://www.ncbi.nlm.nih.gov/pubmed/19900527
(10) http://www.ncbi.nlm.nih.gov/pubmed/19178774

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Herbal therapy: Popular Herbal Wormwood (Artemisia absinthium)

Kyle J. Norton(Scholar and Master of Nutrients, all right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

Wormwood (Artemisia absinthium)

Wormwood is a herbaceous, perennial plant in the genus Artemisia, belonging to The family Asteraceae, native to Europe and naturalized in northeastern North America. The herb has been used in traditional medicine as a sedative and anti-inflammatory agent and cardiac stimulation and to treat gastrointestinal disorders, fever, irregular menstruation, loss of appetite , improve memory and for the restoration of declining mental function, etc.

Health Benefits
1. Neuroprotective effect
In the identification of investigate the potential protective effects of Artemisia absinthium on cerebral oxidative stress and damage as well as behavioral disturbances induced by cerebral ischemia and reperfusion injury in rats, found that The brain oxidative stress and damage, and behavioral deficits were significantly attenuated by pre-treatment with the methanol extract of Artemisia absinthium (100 mg/kg and 200 mg/kg, p.o.) and concluded that Artemisia absinthium is neuroprotective and may prove to be useful adjunct in the treatment of stroke, according to "Neuroprotective effect of Artemisia absinthium L. on focal ischemia and reperfusion-induced cerebral injury" by Bora KS, Sharma A.(1)

2. Cognitive effects
In the determination of the effect of wornwood on TNF-alpha in Crohn's Disease (CD) patients found that Average serum TNF-alpha level fell from 24.5+/-3.5pg/ml at baseline to 8.0+/-2.5pg/ml after six weeks. The corresponding levels in the control group were 25.7+/-4.6 (week 0), and 21.1+/-3.2 (week 6). On the clinical side, Crohn's Disease Activity Index (CDAI) scores fell from 275+/-15 to below 175+/-12 in wormwood group with remission of symptoms in eight patients (CDAI score below 170 or reduction by 70 points), compared to only two in the placebo group (CDAI of placebo group 282+/-11 at baseline and 230+/-14 on week 6), according to "Wormwood (Artemisia absinthium) suppresses tumour necrosis factor alpha and accelerates healing in patients with Crohn's disease - A controlled clinical trial" by Krebs S, Omer TN, Omer B.(2)

3. Antioxidants
In the evaluatiopn of the methanol extract of Artemisia absinthium Linn. (Asteraceae; MAB) for its in vitro free-radical scavenging effects using different classical assays, and in vivo antioxidant activity using global cerebral ischemia and reperfusion (I/R)-induced oxidative stress in mice, found that methanol extract of A. absinthium showed significant (p<0.05) superoxide anion, hydrogen peroxide, hydroxyl and nitric oxide radical scavenging activities, and significant reducing power. Furthermore, in the in vivo studies, oral administration of MAB (100 or 200 mg/kg) inhibited cerebral I/R-induced oxidative stress by decreasing TBARS, and restoring levels of superoxide dismutase (SOD) and glutathione (GSH), according to "Evaluation of antioxidant and free-radical scavenging potential of Artemisia absinthium" by Bora KS, Sharma A.(3)

4. Anti-diabetes
In the clarification of the use of thujone, a monoterpene ketone often present in sage (Salvia officinalis L.) or wormwood (Artemisia absinthium L.), for the treatment of diabetes mellitus, found that after oral treatment with thujone (5 mg/kg bodyweight (bw)/day for 28 days), the cholesterol and triglyceride levels were significantly adjusted to normal levels when compared to diabetic, untreated rats. While these results sound promising and worthy of further investigation, the well-defined profile of the adverse properties of thujone demands a cautious interpretation of these results. The therapeutic margin of thujone appears to be small, as a dose-related incidence of seizures was noted in 2-year National Toxicology Program studies in rats and mice. The dose level in the diabetic rat study is also considerably higher than a daily intake that is acceptable for humans (0.1 mg/kg bw/day), according to "The choice of thujone as drug for diabetes" by Lachenmeier DW, Walch SG.(4)

5. Cholesterol and triglycerides
In the examination of Thujone effects on lipid profile (cholesterol and triglycerides) in diabetic rats, found that Oral treatment with thujone (5 mg kg⁻¹ body weight dose) significantly adjusted cholesterol and triglyceride levels in diabetic rats (p ≤ 0.05) to normal levels compared to diabetic untreated rats, according to " Thujone corrects cholesterol and triglyceride profiles in diabetic rat model" by Baddar NW, Aburjai TA, Taha MO, Disi AM.(5)

6. Anti-malarial activity
In the evaluation of the anti-malarial activity of three medicinal plants, Picrorhiza kurroa, Caesalpinia bonducella and Artemisia absinthium of Pakistan, found that Artemisia absinthium, aqueous, cold alcoholic and hot alcoholic extract of Artemisia absinthium showed 35%, 55% and 21% inhibition in growth of Plasmodium falciparum, respectively at 2.00 mg/ml. In our study, extracts of Picrorhiza kurroa were found good for traditional therapy with highly significant results, according to "Antimalarial activity of three Pakistani medicinal plants" by
Irshad S, Mannan A, Mirza B.(6)

7. Antimicrobial activity
In the assessment of the antibacterial and antifungal potential of some Romanian medicinal plants, arnica--Arnica montana, wormwood--Artemisia absinthium and nettle--Urtica dioica,
indicated that in vitro, the studied plant extracts are a significant source of natural alternatives to antimicrobial therapy, thus avoiding antibiotic therapy, the use of which has become excessive in recent years, according to "In vitro antimicrobial activity of Romanian medicinal plants hydroalcoholic extracts on planktonic and adhered cells" by Stanciuc AM, Gaspar A, Moldovan L, Saviuc C, Popa M, Măruţescu L.(7)

8. Antiparasitic effects
In the determination of the efficiency of A. absinthium extract on cats naturally infected with Toxocara cati and the the extract on the embryonic development of T. cati eggs in vitro,
found that in the treatment period, the activities of ALT, AST, ALP, urea and creatinine were located within the physiological ranges in cats. In in vitro trials with A. absinthium extract, the embryonic development of T. cati eggs was identical in all groups (treatment and control). A. absinthium extract did not inhibit larval development in eggs in in vitro trials, according to "Antiparasitic efficiency of Artemisia absinthium on Toxocara cati in naturally infected cats" by Yıldız K, Başalan M, Duru O, Gökpınar S.(8)

9. Hepatoprotective activity
In the evaluation in vivo, the hepatoprotective activity of the aqueous extract of Artemisia absinthium L. (AEAA), found that pretreatment with AEAA significantly (P<0.001) and dose-dependently prevented chemically or immunologically induced increase in serum levels of hepatic enzymes. Furthermore, AEAA significantly (P<0.05) reduced the lipid peroxidation in the liver tissue and restored activities of defense antioxidant enzymes SOD and GPx towards normal levels. In the BCG/LPS model, increase of the levels of important pro-inflammatory mediators TNF-alpha and IL-1 was significantly (P<0.01) suppressed by AEAA pretreatment, according to " In vivo hepatoprotective activity of the aqueous extract of Artemisia absinthium L. against chemically and immunologically induced liver injuries in mice" by Amat N, Upur H, Blazeković B.(9)

10. Etc.

Side effects
1. Do not use the herb if you have experienced seizures and ulcers
2. Do not use Wormwood in newborn, children, or if you are pregnant or breasr feeding without approval from the related field specialist
3. Overdoses can be toxic and cause liver damage
4. It may cause allergic effect to people who are allergic to ragweed and daisies.
5. Etc.

Pregnancy Miracle
Reverse Infertility And Get Pregnant Naturally
Using Holistic Ancient Chinese Medicine

Sources
(1) http://www.ncbi.nlm.nih.gov/pubmed/20435123
(2) http://www.ncbi.nlm.nih.gov/pubmed/19962291
(3) http://www.ncbi.nlm.nih.gov/pubmed/21999109
(4) http://www.ncbi.nlm.nih.gov/pubmed/21988529
(5) http://www.ncbi.nlm.nih.gov/pubmed/21740283
(6) http://www.ncbi.nlm.nih.gov/pubmed/21959826
(7) http://www.ncbi.nlm.nih.gov/pubmed/21717806
(8) http://www.ncbi.nlm.nih.gov/pubmed/21618184
(9) http://www.ncbi.nlm.nih.gov/pubmed/20637853

Wednesday, September 28, 2016

Phytochemicals in Foods- The Effects of Naringenin

Kyle J. Norton(Scholar and Master of Nutrients, all right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

Naringenin

Naringenin, a flavanone, belonging to the red, blue, purple pigments of Flavonoids (polyphenols) found predominantly in citrus fruits is considered as one of powerful antioxiant with many health benefits.

Health benefits
1. Antioxidant, radical scavenging and biomolecule activity
In the affirmation of the capacity of flavonoid naringenin and its glycoside naringin in the comparison of theirs antioxidant capacities, radical scavenging and biomolecule activities found that naringenin exhibited higher antioxidant capacity and hydroxyl and superoxide radical scavenger efficiency than naringin and both flavanones were equally effective in reducing DNA damage. However, they show no protective effect on oxidation of GSH, according to the study of "Antioxidantproperties, radical scavenging activity and biomolecule protection capacity of flavonoid naringenin and its glycoside naringin: a comparative study" byCavia-Saiz M, Busto MD, Pilar-Izquierdo MC, Ortega N, Perez-Mateos M, Muñiz P.(1)

2. Colon cancer
In the comparison of flavonoids and limonoids and theirs effects on colon cancer found that The ability of dietary apigenin and naringenin to reduce HMACF, lower proliferation (naringenin only) and increase apoptosis may contribute toward colon cancer prevention, according to "Apigenin and naringenin suppress colon carcinogenesis through the aberrant crypt stage in azoxymethane-treated rats" by Leonardi T, Vanamala J, Taddeo SS, Davidson LA, Murphy ME, Patil BS, Wang N, Carroll RJ, Chapkin RS,Lupton JR, Turner ND.(2)

3. Lung metastasis
In the investigation of Naringenin and its defect in lung metastasis in a breast cancer found that orally administered naringenin significantly decreased the number of metastatic tumor cells in the lung and extended the life span of tumor resected mice. Flow cytometry analysis revealed that T cells displayed enhanced antitumor activity in naringenin treated mice, with an increased proportion of IFN-γ and IL-2 expressing T cells, according to the study of "Naringenin reduces lung metastasis in a breast cancer resection model" by Qin L, Jin L, Lu L, Lu X, Zhang C, Zhang F, Liang W.(3)

4. Anti cancers and tumors
In the study of Naringenin and its anti cancer and tumor effects found that NGEN promotes apoptosis in rat C6 glioma model by promoting the apoptotic effect, modulation of Bcl-2/Bax ratio leads to release of Cyt C from mitochondria, thereby activation of caspase-3 and caspase-9 is mediated by enhanced expression of Cx43, according to "Naringenin promote apoptosis in cerebrally implanted C6 glioma cells" by Sabarinathan D, Mahalakshmi P, Vanisree AJ.(4)

5. Pulmonary fibrosis
In the analyzing Naringenin and its effect in idiopathic pulmonary fibrosis which can lead to lung cancer found that Naringenin significantly reduces lung metastases in mice with pulmonary fibrosis and increases their survival by improving the immunosuppressive environment through down-regulating transforming growth factor-beta1 and reducing regulatory T cells. Naringenin could be an ideal therapeutic agent in the treatment of both cancer and fibrosis, according to "Naringenin: a potential immunomodulator for inhibiting lung fibrosis and metastasis" by Du G, Jin L, Han X, Song Z, Zhang H, Liang W.(5)

6. Multidrug-resistant cancer cells
In the observation of 12 phenolic compounds, including three stilbenes, two flavonoids, two coumarins, one neolignan, and four lignans, isolated from Euphorbia and Pycnanthus species or obtained by derivatization and theirs effects against multidrug-resistant human cancer cells found that the most active compound was the flavonoid naringenin, found to be 15-fold more effective against the atypical MDR subline of gastric carcinoma than in parental drug-sensitive cells, according to "Phenolic compounds as selective antineoplasic agents against multidrug-resistant human cancer cells' by Duarte N, Lage H, Abrantes M, Ferreira MJ.(6)

7. Hepatic lipid metabolism
In the examination of naringenin and its effect of disruption of lipid andcarbohydrate homeostasis which may contribute to an important factor in the development of prevalent metabolic diseases such as diabetes, obesity, and atherosclerosis found that naringenin regulates the activity of nuclear receptors PPARalpha, PPARgamma, and LXRalpha as it activates the ligand-binding domain of both PPARalpha and PPARgamma, while inhibiting LXRalpha in GAL4-fusion reporters, according to "Transcriptional regulation of human and rat hepatic lipid metabolism by the grapefruit flavonoid naringenin: role of PPARalpha, PPARgamma and LXRalpha" by Goldwasser J, Cohen PY, Yang E, Balaguer P, Yarmush ML, Nahmias Y.(7)

8. Hepatitis C virus (HCV)
In the evaluation of naringenin and its effect Hepatitis C virus (HCV) infection found that naringenin is a non-toxic assembly inhibitor of HCV and that other PPARα agonists play a similar role in blocking viral production. The combination ofnaringenin with STAT-C agents could potentially bring a rapid reduction in HCV levels during the early treatment phase, an outcome associated with sustained virological response, according to "Naringenin inhibits the assembly and long-term production of infectious hepatitis C virus particles through a PPAR-mediated mechanism" by Goldwasser J, Cohen PY, Lin W, Kitsberg D, Balaguer P, Polyak SJ, Chung RT, Yarmush ML, Nahmias Y.(8)

9. Cholesterol-lowering activity
In the affirmation of naringenin and its Cholesterol-lowering effect found thatnaringenin lowers the plasma and hepatic cholesterol concentrations by suppressing HMG-CoA reductase and ACAT in rats fed a high-cholesterol diet, according to "Cholesterol-lowering activity of naringenin via inhibition of 3-hydroxy-3-methylglutaryl coenzyme A reductase and acyl coenzyme A:cholesterol acyltransferase in rats" by Lee SH, Park YB, Bae KH, Bok SH, Kwon YK, Lee ES, Choi MS.(9)

10. Anti-inflammatory effects
In the evaluation of the mechanisms of action of the effective compounds. Flavone, the isoflavones daidzein and genistein, the flavonols isorhamnetin, kaempferol and quercetin, the flavanone naringenin, and the anthocyanin pelargonidin amd theirs anti-inflammatory effects found that they inhibited iNOS protein and mRNA expression and also NO production in a dose-dependent manner, according to "Anti-inflammatory effects of flavonoids: genistein, kaempferol, quercetin, and daidzein inhibit STAT-1 and NF-kappaB activations, whereas flavone, isorhamnetin, naringenin, and pelargonidin inhibit only NF-kappaB activation along with their inhibitory effect on iNOS expression and NO production in activated macrophages" by Hämäläinen M, Nieminen R, Vuorela P, Heinonen M, Moilanen E.(10)

11. Immunity
In the unvestigation of Naringenin, a flavonoid in grapefruits and citrus fruits and its effec in immune system found that naringenin potently suppressed picryl chloride (PCl)-induced contact hypersensitivity by inhibiting the proliferation and activation of T lymphocytes. In vitro, both of the activated hapten-specific T cells and the T cells stimulated with anti-CD3/anti-CD28 showed growth arrest afternaringenin treatment, according to "A novel regulatory mechanism ofnaringenin through inhibition of T lymphocyte function in contact hypersensitivity suppression" by Fang F, Tang Y, Gao Z, Xu Q.(11)

12. Etc.

Pregnancy Miracle
Reverse Infertility And Get Pregnant Naturally
Using Holistic Ancient Chinese Medicine