Monday, December 24, 2018

Cruciferous Vegetables, The Natural Chemopreventive Veggies Protect Our Body Against Cancers Caused by Chemical Toxins, Scientists Reveal

Cruciferous vegetables, rich of phytochemicals may be considered as the functional food for prevention of cancers caused by chemical carcinogens some studies suggested.

Chemical carcinogens, types of chemical toxins, can induce cellular and chromosomes change and DNA damage, causing mutation of healthy cells, the initial stage of cancer development.

According to the National Toxicology Program 14th Report on Carcinogens “Known to be human carcinogens” provided by the American Cancer Society, there are many different types of chemical carcinogens, including
* Lifestyle factors (nutrition, tobacco use, physical activity, etc.)

* Naturally occurring exposures (ultraviolet light, radon gas, infectious agents, etc.)

* Medical treatments (radiation and medicines including chemotherapy, hormone drugs, drugs that suppress the immune system, etc.)

* Workplace Exposures

* Household exposures

* Pollution
Cancers are class of medical diseases characterized by cell multiply disorderly and uncontrollably.

At the advanced stage, most cancers can travel a distance away from the site of origin to infect other healthy cells and tissue via lymph and blood.

According to the Universidade Federal de Ouro Preto, sulforaphane (SFN), the isothiocyanate (ITC) group of organosulfur compounds found in cruciferous vegetable expressed chemopreventive properties involved detoxification processes of chemical carcinogens.

Dr. de Figueiredo SM, the lead author said, " In a dose-dependent manner, ITC inhibits the viability of human cancer cells, modifies epigenetic events that occur in cancer cells and present antiinflammatory effect acting during the initial of uncontrolled cell proliferation."

The chemoprotective activity of the cruciferous vegetable was attributed to significant expression of the antioxidants in cell cycle arrest and apoptosis of cancer cells.

Furthermore, its phytochemicals also can act as the post-initiation stages of carcinogenesis, 'suppressing' agent involving the ability to modulate the Nrf2 which is a protein with unique function of regulating expression of antioxidant proteins that protect against oxidative damage triggered by injury and inflammation.

In fact, besides using as a chemopreventive agent against chemical carcinogenesis, sulforaphane (SFN), the major chemical constituent of cruciferous vegetables also inhibited the drug-metabolizing enzymes that cause activation/neutralization of carcinogenic metabolites and protected normal healthy cells from environmental toxin inducing of cancers.

Moreover, the phytochemical exhibited the molecular mechanisms responsible for the overall chemopreventive effects on selective cytotoxicity, the unique function of inhibiting oxidate stress, free radicals produced by lipid peroxidation in cells.

Additionally, in tobacco smoke carcinogens induced chemical tumors, cruciferous vegetable consumption has shown to inversely associate the development of cancer.

In animal experiments. the chemopreventive effects of isothiocyanates, another compound found cruciferous vegetable, inhibited the metabolic activation of carcinogens by cytochrome P450s, enzymes with the function of metabolized potentially toxic compounds.

Taking together, intake of cruciferous vegetables have a potential health benefit against environment toxins that initiates the early onset of cancers. But due to the small size of the sample, further studies are necessary to address the veggies anti cancers possibility.

Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight

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Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca


Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)

Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blog, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Chemoprotection by sulforaphane: keep one eye beyond Keap1 by Myzak MC1, Dashwood RH.(PubMed)
(2) The antioxidant properties of organosulfur compounds (sulforaphane) by de Figueiredo SM1, Binda NS, Nogueira-Machado JA, Vieira-Filho SA, Caligiorne RB.(PubMed)
(3) Role of 4-hydroxynonenal in chemopreventive activities of sulforaphane by Sharma R1, Sharma A, Chaudhary P, Sahu M, Jaiswal S, Awasthi S, Awasthi YC.(PubMed)

Sunday, December 23, 2018

Yoga Intervention Can Alleviate Pain and Treat Rheumatic Diseases, Researchers Suggest

Yoga intervention may have a profound effect to alleviate pain and treat rheumatic diseases, some studies suggested.

Rheumatic diseases are a condition of Musculoskeletal disorders, affecting the joints and muscles.

Yoga, the accident technique practice for harmonized external and internal body well being, through breath control, meditation, bodily movement, and gesture..... has been best known for people in the Western world and some parts in Asia.

In a study to compare the effect of Tai Chi and yoga therapies in treatments for rheumatologic and musculoskeletal diseases, researchers filed the following report
* Both therapy displays a significant effect of Tai Chi and yoga in the management of rheumatologic diseases, particularly in osteoarthritis of the knee, hip and hand, and rheumatoid arthritis pain.

* Tai Chi and yoga are safe, expressed a reduction of pain and improvement of physical function and quality of life in patients with rheumatic diseases.

By the information collected, Uhlig T, the led authors said, "Recommendations for Tai Chi in knee osteoarthritis have recently been issued by the American College of Rheumatology. To allow broader recommendations for the use of Tai Chi and yoga in rheumatic diseases".

The study from McGill University, Montreal suggested that yoga lessons not only improve stress and anxiety and promote a sense of calmness, general well-being, and quality of life but also reduced inflammatory mediators including C-reactive protein and interleukin-6 in overexpression pain in participants with rheumatic disease.

Truly, regular yoga practice can increase muscle strength and endurance, proprioception, the sense equilibrium, and balance, depending on the notion of force and balance, with emphasis on movement through a full range of motion to increase flexibility and mobility, thus reducing physical symptoms in patients with rheumatic diseases.

Some researchers suggested that regular yoga practice
* can improve stress management and can have a feedback effect on improving chronic pain, through affecting the response to pain, decreasing the level of perceived suffering.

* can improve movement of joints, as motion and muscles stretching can decrease the intensity of pain or relieve your pain completely in some patients.

Furthermore, yoga breathing and medication also were found to reduce chronic pain through calming the nervous system to block respond to pain messages, reduce inflammatory chemicals from communicating with nerves and increase the release of natural pain-relieving chemicals called endorphins.

However, in the review of randomized controlled trials (RCTs) by comparing yoga with control interventions in patients with rheumatic diseases by searching database of Medline/PubMed, Scopus, the Cochrane Library and IndMED through February 2013, eight RCTs selected met the guideline with a total of 559 subjects with two RCTs with a low risk of bias, researchers found that all studies expressed a very low evidence for effects on pain and disability, in patients with rheumatic diseases participated in yoga classes, long and short terms.

Taking all together, yoga practice may have a profound effect to alleviate pain and treat rheumatic diseases, however, larger randomized controlled trials. are necessary to reaffirm these possibilities


Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight

How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca


Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)

Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blog, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.


Sources
(1) Yoga for rheumatic diseases: a systematic review by Cramer H1, Lauche R, Langhorst J, Dobos G.(PubMed)
(2) Yoga in rheumatic diseases by Bartlett SJ1, Moonaz SH, Mill C, Bernatsky S, Bingham CO 3rd.(PubMed)
(3) Tai Chi and yoga as complementary therapies in rheumatologic conditions by Uhlig T1.(PubMed)

Saturday, December 22, 2018

Yoga Improves All Aspects in Patients with Osteoporosis

Yoga participated may benefit to individuals with osteoporosis by reducing complications of fractures, some studies suggested.

Osteoporosis is a Musculoskeletal disorder (MSDs) medical condition, characterized by decreased bone density.

The exact causes of osteoporosis are unknown. Neither researchers understood that people with the same health conditions, some are affected by the imbalance between new bone formation and bone resorption while others do not.

However, researchers do know that certain risk factors such as a lid to increase lifelong calcium-deficient diet, age, female, family history,.... bone structure and overweight are associated with the early onset of osteoporosis.

Furthermore, long-term intake of certain medications such as prednisone and a medical condition such as rheumatoid arthritis are also the osteoporosis prevalent risk factors

According to the statistic, 1 in 3 women and 1 in 5 men older than 50 will suffer from an osteoporosis fracture, worldwide.

Yoga, the ancient practice for harmonized external and internal body well being, through breath control, meditation, bodily movement, and gesture..... has been well known to people the in Western world and some parts in Asia.

Some of yoga health benefits were reported by various respectable institutes' research and supported by health advocates.

In the review of literature published in PubMed, Medline, and Cochrane databases between 1966 and 2011 about topics related to osteoporosis and spinal movement. researchers found that
*Yoga, as a moderate form of exercise showed to strengthen the muscles supporting the spinal column, promote balance, improve posture, and enhance the quality of life.

* Yoga attendees may also benefit from varied spinal movement in preserving the health and strength of the vertebral bodies.

* Yoga exercise modified by experts may be helpful in reduced risk fracture depending on the risk of vertebral fractures of attendees

After adjusting to other risk factors, Dr, Smith EN the led author said, "Yoga therapists are cautioned to not apply a one-size-fits-all approach when working with this population".
Furthermore, the study also concerned that more studies are needed to further evaluate yoga poses presence which provides the least risk and greatest benefit to individuals with osteoporosis.

Physically, yoga postures and exercise exert a significant effect of stimulating bone metabolism and enhance physical function. the As impact of moderate exercises is recognized as beneficial for the stimulation of bone tissue, muscle strength, type of muscle contraction associated with changes in bone metabolism.

Additionally, in the support of the above differentiation, researchers at the Istanbul University conducted a review of literature posted in databases with 26 postmenopausal osteoporotic women over 55 years of age satisfied the criteria selected found that* Yoga may be used as a form of exercise in the field of osteoporosis rehabilitation.

* Yoga lessons expressed a positive influence on balance, posture, flexibility, and life quality.

* Yoga education has a positive effect on pain, physical functions, social functions, general, particularly in post postmenopausal osteoporotic women.

However, according to the reports from the Mayo Clinic in the examine 3 patients with osteopenia, but in good health and pain-free, and started yoga exercises to improve their musculoskeletal health, researchers warned, yoga class without tailoring to individual students needed may induce pain and complications with some flexion yoga positions in the patients with osteopenia of that can lead to concern that fracture risk and increased even further in osteoporosis.

Dr. Sinaki M, said, "Although exercise has been shown to be effective for improving bone mineral density and decreasing fracture risk, our subjects had the development of VCFs and neck and back pain with yoga exercises. This finding suggests that factors other than bone mass should be considered for exercise counseling in patients with bone loss. The increased torque pressure applied to vertebral bodies during SFEs may be a risk".
Furthermore, the study also advises that even though yoga exercise prescribed for patients with the vertebral bone loss, is effective and important for treatment of osteopenia and osteoporosis but instructors should need to know some positions can contribute to extreme state ain on spines with bone loss.

Taking all together, yoga may be considered as an integrated form of exercise in all ages, but in the older population with osteoporosis, yoga instructors should select an applicable lesson which provides the least risk and greatest benefit to individuals with osteoporosis.


Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight

How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca


Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)

Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.


Sources
(1) Yoga, vertebral fractures, and osteoporosis: research and recommendations by Smith EN, Boser A.(PubMed)
(2) Yoga spinal flexion positions and vertebral compression fracture in osteopenia or osteoporosis of spine: case series by Sinaki M1. (PubMed)
(3) Yoga might be an alternative training for the quality of life and balance in postmenopausal osteoporosis by Tüzün S1, Aktas I, Akarirmak U, Sipahi S, Tüzün F.(PubMed)

Friday, December 21, 2018

The Herb and Plant Inhibits Mucus Accumulation That Cause Acute and Chronic Cough, Scientists Show

Fennel may have a potential and positive effect in reduced cough through its expectorant activity, some scientists suggested.

The results of the study were conducted by numbers of institutes, including the Kaunas University of Medicine and published on online literature
is a natural and infrequent reaction of the body to clear the throat caused by excessive mucus or foreign irritants. The aim of these function is to make the airway free for air inhaling and expelling.

Acute coughing normally caused by hay fever and the common cold is healed itself within 3 weeks. Chronic coughing is a condition that lasts longer than 3 weeks.

As of today, researchers do not know the exact causes of chronic coughing. However, researchers suggested, the condition may result of postnasal drip, asthma, gastroesophageal reflux disease (GERD),... and chronic bronchitis. And cigarette smoking is considered as the main culprit.

Long-term use of an ACE inhibitor, a pharmaceutical drug used primarily for the treatment of hypertension and congestive heart failure are also associated with the risk of a chronic cough.


Dr. Terasaki G, the lead author at the University of Washington, said, " Cough hypersensitivity syndrome is a new area of research and has been hypothesized to be the underlying factor in many cases of a chronic cough, regardless of the inciting factor" and " More clinical research is needed to further elucidate the cough reflex pathway and the factors involved in modulating its sensitivity, which may eventually lead to new antitussive therapeutics"(5).

An expectorant is a medicine with a function to promote the secretion of sputum of the air passages for treatment of coughs.

Fennel (Foeniculum vulgare) is a plant species of the genus, belongings to Apiaceae (Umbelliferae), native to the Mediterranean.

The herb or food has been used in traditional and herbal medicine as warming, carminative, antispasmodic, antidepressant agent and to stimulate the appetite, ease indigestion, soothe coughing, reduce intestinal spasms, to regulate the menstrual cycle and relieve PMS,...

In the comparison of the effect of some herbal agents in velocity of mucus secretion isolated from the ciliated epithelium of the frog esophagus, researchers found that application fo fructus foeniculi (fennel) exerts a stronger effect than fructus anisi (anise). Herba plantaginis (plantain), flores verbasci (torch weed), and radix liquiritiae (liquorice) but lessers than the application of Folia farfarae (coltsfoot).



This protective effect in the further analysis was found to attribute to mucus layers in the hypopharynx and spasmolytic, secretolytic and bactericide effects found in fennel.


Furthermore, in the experiment to confirm the efficacy of some herbal medicine for treatment of throat clearing used since ancient times, researchers conducted a study to evaluate the bronchial mucus secretion stimulating and antispasmodic, antimicrobial, antiphlogistic and stimulating effect on the ciliated epithelium of two new formulations of throat clearing herbal tea.
The first formulation consists of licorice roots, sweet fennel, and thyme, and the second one consists of pine gemmae, thyme, and elderflowers.

At the end of the experiment, researchers showed that both formulas exerted a significant activity against in inhibited mucus secretion in tested subjects without inducing intolerant adverse effects.

However, loss of the efficacy was found in use of formulas after 2 years of expiration, and the purity of the mixtures may also be decreased due to loss on drying, total ash, microbial contamination, contamination with radionuclides, heavy metals, pesticides, and foreign matter.

These result suggested that although herbal medicine may be effective in exhibited mucus secretion for treatment of a cough, appliers should also be beware of the contamination caused by several aspects.

Moreover, in the investigation to a water extract of a mixture of eight herbs (chamomile, saffron, anise, fennel, caraway, licorice, cardamom and black seed) tested for its inhibitory effect on histamine released in initiated cough from rat peritoneal mast cells stimulated either by compound 48/80 or be IgE/anti-IgE, researchers at the Helwan University indicated that in compared to flavonoid quercetin, the extract demonstrated inhibited histamine released from chemically- and immunologically-induced cells by 81% and 85%, respectively.

Intake of the water extract of tested subjects also displayed a significantly and clinically expectorant expectancy in improvements of sleep discomfort, cough frequency, and cough intensity.

The application also increased percentages of FEV1/FVC in patients suffering from allergic asthma in compared to placebo tea participants.

Where The FEV1/FVC ratio, also called Tiffeneau-Pinelli index, is a calculated ratio used in the diagnosis of obstructive and restrictive lung disease, according to Wikipedia

FEV1: Volume that has been exhaled at the end of the first second of a forced expiration

VC: Vital capacity: the volume of air breathed out after the deepest inhalation
RV/TLC%: Residual volume expressed as percent of TLC

FEFmax: The maximum instantaneous flow achieved during an FVC maneuver

VL: Actual volume of the lung including the volume of the conducting airway

FRC: Functional residual capacity: the volume in the lungs at the end-expiratory position

TLC: Total lung capacity: the volume in the lungs at maximal inflation, the sum of VC and RV


Taken together, fennel used alone or combined with other herbal medicine may be used to get rid of mucus, improve quality of life and treat asthma.



Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight

How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca


Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)

Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma ISSN 0975-6299.


Sources
(1) [Effect of various phytotherapeutic expectorants on mucociliary transport].[Article in German] by Müller-Limmroth W, Fröhlich HH.(PubMed)
(2) The effect of a herbal water-extract on histamine release from mast cells and on allergic asthma by Haggag EG1, Abou-Moustafa MA, Boucher W, Theoharides TC.(PubMed)
(3) [Use of herbal medicine in German children - prevalence, indications and motivation].[Article in German]by Hümer M1, Scheller G, Kapellen T, Gebauer C, Schmidt H, Kiess W.(PubMed)
(4) FEV1/FVC ratio(Wikipedia)
(5) Evaluation and treatment of chronic cough by Terasaki G 1 , Paauw DS(PubMed)

Thursday, December 20, 2018

Butterbur, The Functional Herb Which Protects Neurons Integrity, Scientist Find

Scientists have found a herbal plant which processes a potential and therapeutic effect in the protection against damage and death of neurons.

Neuroprotective effects are the protection against anything which causes harm to the brain and spinal cord

In other words, herbal butterbur promotes neuronal integrity against the reduction in the rate of neuronal loss that causes neurodegenerative disease.

Dr. Vajda FJ, the scientist at the St. Vincent's Hospital, Melbourne in the expression of neuro diseases said, "neuroprotection is an effect that may result in salvage, recovery or regeneration of the nervous system, its cells, structure, and function. It is thought that there are many neurochemical modulators of nervous system damage" and " Acute and chronic nervous system damage in response to an insult may lead to acute or delayed neuronal death, apoptotic cell death, neuronal degeneration, injury and loss, and gliosis"(4).

The Mcgovern Institute in the article related to brain disorder wrote, "Many brain disorders are chronic and incurable conditions whose disabling effects may continue for years or even decades. Thus, the overall disease burden from these disorders is much greater than would be suggested by mortality figures alone. The extent of this burden is underlined by data from the World Health Organization".

Most common brain disease neurodegenerative disease including Alzheimer's disease (AD), Parkinson's disease (PD), and amyotrophic lateral sclerosis (ALS), affecting millions of people worldwide.

And, dementia is an umbrella term that describes a variety of diseases and conditions caused by nerve cells in the brain die or no longer function normally. Symptoms may affect memory, behavior, and ability to think clearly.


According to statistic, approximately over 5.7 million Americans of all ages have Alzheimer's. as of 2018, 1 in 8 people age 65 and older (10 percent) has Alzheimer's disease in the US. Sadly, The numbers of Alzheimer's disease are growing and growing fast.

Butterbur, found in wet, marshy, damp land, including wetland, riverside, forest, etc., is a creeping underground plant, genus Petasites of 15 -20 species, belonging to the family Asteraceae, native to Northern Hemisphere.

The herbal medicine has been used in herbal medicine as a pain reliever in the digestive system, including stomach, bile ducts,...... and duodenum.

The Ingredients
The chemical constituents of Butterbur include Petioles, petasitene and pethybrene, quercetin 3-O-beta-D-glucoside, quercetin 3-O-beta-D-6''-O-acetylglucoside, and rutin, caffeic acid, alkaloids, S-petasin, and iso-S-petasin, etc.

In the study to investigate neuroprotective effects in a rat transient focal cerebral ischemia-reperfusion model, and in an in vitro cerebral ischemia model, oxygen-glucose deprivation of cultured nerve cells, researchers found that application of total bakkenolides, a major bioactive constituent isolated immediately after reperfusion at doses of 5, 10 and 20 mg/kg markedly reduced brain infarct volume and neurological deficits.

Additional analysis also suggested, the administrated doses also significantly attenuated cell death and apoptosis in primary cultured neurons subject to 1-h hypoxia followed by 24-h reoxygenation.

The efficacy of herbal butterbur in protected neurons was attributed by total bakkenolides in inhibited an enzyme activators with function in propagated the cellular response to inflammation through NF-κB, a protein complex regulated transcription of DNA, cytokine production and cell survival.

In other words, application of total bakkenolides reduced brain infarct volume and overexpression of pro-inflammation cytokines in response to focal cerebral ischemia-reperfusion that have a strong impact in decreased neuro cell damage and death at the site of reperfusion injury.

Dr. Jiang Q, the lead author after taking into account of other co and confounder said, "(The) results provide a strong pharmacological basis for further understanding the potential therapeutic role of total bakkenolides in cerebral ischemic disease.


Some researchers in the study of Bakkenolides in primary cultured neurons exposed to oxygen-glucose deprivation and oxidative insults suggested, Bakkenolides exerted neuroprotective effects may be results from properties of its antioxidant properties.


Moreover, petaslignolide A (PA), a furfuran lignan isolated from butanol fraction of Petasites japonicus (Sieb. et Zucc.) (Compositae) leaves in study of the oxidative damage in the brain of mice, facilitated a significant effect at dose of 40 mg/kg in alleviated the behavioral signs of kainic acid neurotoxicity and reduced the mortality (50%) by kainic acid to 12.5%.

Administration of PA also restore the levels of antioxidants in the mice that were reduced by injection of kainic acid in compared to control.

Further analysis found that PA (40 mg/kg) effectiveness is comparable to those of butanol fraction (200 mg/kg) of P. japonicus extract in reducing kainic acid neurotoxicity.


These results indicated that butanol fraction (200 mg/kg) of P. japonicus extract exhibited strong neuroprotective, probably is due to the presence of petaslignolide A (PA).


The findings suggested herbal butterbur may be considered as a functional herb for neuroprotection, however, the volume of the herb used should only be prescribed herbal doctor.

However, further data collection on large example size and multi-centers studies performed with human consumption of the whole food during the course of the disease will be necessary to complete the picture of butterbur neuroprotective possibilities.


.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight

How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca


Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)

Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma ISSN 0975-6299.
References
(1) Total Bakkenolides Protects Neurons against Cerebral Ischemic Injury through Inhibition of Nuclear Factor-Κb Activation by Jiang Q, Xia Yy EY, Jm HE, Guo Ml EY, Rp LI.(PubMed)
(2) Bakkenolides from Petasites tricholobus and their neuroprotective effects related to antioxidant activities by Wang YL, Li RP, Guo ML, Zhang G, Zhang N, Ma YL.(PubMed)
(3) Protection by petaslignolide A, a major neuroprotective compound in the butanol extract of Petasites japonicus leaves, against oxidative damage in the brains of mice challenged with kainic acid by Cui HS, Kim MR, Sok DE.(PubMed)
(4) Neuroprotection and neurodegenerative disease by Vajda FJ(PubMed)

Wednesday, December 19, 2018

Strawberry and It's Bioactive Flavonoids That Eradicate Risk Factors of Heart Disease

Scientists may have found a fruit which has a potential effect in reduced risk and treatment of heart disease, some studies suggested.

According to statistic, heart disease, after lung cancer kills more than 2,000 Americans every day.

Approximately, 60 million Americans have heart disease.

There are many causes of heart diseases.

Most of the heart diseases are caused by high blood pressure which contributes to hardening of the arteries.

Some researchers suggested that diet high in saturated and trans fats also plays an important role in the initiated risk of coronary heart disease. As the long-term unhealthy diet can cause obesity, high blood pressure,... and diabetes.

Dr. McNamara DJ, in the study of dietary cholesterol, heart disease risk and cognitive dissonance, wrote, "....dietary cholesterol has a small effect on the plasma cholesterol levels with an increase in the cholesterol content of the LDL particle and an increase in HDL cholesterol, with little effect on the LDL: HDL ratio, a significant indicator of heart disease risk"(4).

Truly, everything that adds to the formation of atherosclerosis lesions, damages the inner lining of blood vessels and impedes the transportation of oxygen and nutrition to the heart, is considered prevalent risk factors of arterial blockage, the main cause of heart disease.

Strawberry is a genius of Fragaria × ananassa belongings to the family Roseaceae.

The edible plants have been grown all over the world with a suitable climate for commercial profits due to their's health benefits.

Chemicals constituents of strawberry
The major chemical compounds include anthocyanin and ellagitannins and p-Hydroxybenzoic acid, p-coumaric acid, ellagic acid, cyanidin-3-glucoside, pelargonidin-3-glucoside, kaempferol, quercetin, and myricetin.

According to the followed up study to examine the relationship between anthocyanins, the largest group of water-soluble pigments and the risk of MI, anthocyanin, strawberries intake was found to be potential in preventing myocardial infarction (MI) in young and middle-aged women.

Intake of strawberries was also associated with a decreased risk of MI, in a comparison of those consuming >3 servings a week and those with lower intake.

Dr. Cassidy A, the lead scientist, in the study conducted by the University of East Anglia, including a total of 93 600 women 25 to 42 years of age from the database of the Nurses' Health Study (NHS) II, after taking into account of multivariate adjustment said, "An inverse association between higher intake of anthocyanins and risk of MI was observed (hazard ratio, 0.68; 95% confidence interval, 0.49-0.96; P=0.03, highest versus lowest quintiles)".

Further differentiation of the effects of anthocyanins in reduced risk of a heart problem, also found that anthocyanins efficacy may be associated to improve a variety of effects on blood vessels, platelets, and lipoproteins, the coronary heart diseases reducers.

Moreover, the study of participants includes 34 489 postmenopausal women in the Iowa Women's Health Study who were free of CVD and had complete food-frequency questionnaire information that include Intakes of total flavonoids and 7 subclasses categorized into quintiles at baseline, using the proportional hazards rate ratios (RR) to compute for CVD, coronary heart disease (CHD), stroke, and total mortality after 16 y of follow-up, showed,

* There was a significant inverse association between anthocyanidins and CHD, CVD, and total mortality in compared to no intake of proportional hazards rate ratios (RR) of 0.88, 0.91, and 0.90, respectively.

* The proportional hazards rate ratios (RR) between flavanones and CHD [RR for highest quintile versus lowest 0.78 and between flavones and total mortality [RR for highest quintile versus lowest: 0.88.

* Intake of strawberry were associated with significantly reduced risk of cardiovascular diseases in compared to other foods in the questionnaire.
These results suggested that dietary intakes of flavanones, anthocyanidins, and foods rich in flavonoids were associated with reduced risk of death due to CHD, CVD, and all causes, according to Dr. Mink PJ, the lead scientist.

Taken altogether, strawberry with rich of flavanones, anthocyanidins, and flavonoids may be considered as a functional food in the prevention of early onset and treatment of heart disease.

Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca



References
(1) High anthocyanin intake is associated with a reduced risk of myocardial infarction in young and middle-aged women by Cassidy A, Mukamal KJ, Liu L, Franz M, Eliassen AH, Rimm EB..(PubMed)
(2) Anthocyanins and heart health by Mazza GJ. (PubMed)
(3) Flavonoid intake and cardiovascular disease mortality: a prospective study in postmenopausal women. byMink PJ, Scrafford CG, Barraj LM, Harnack L, Hong CP, Nettleton JA, Jacobs DR Jr.(PubMed)
(4) Dietary cholesterol, heart disease risk and cognitive dissonance by McNamara DJ(PubMed)

Tuesday, December 18, 2018

The Kitchen Herbal Cayenne Spice Bioactive Compound Which Has The Potential to Cure Non Allergic Rhinitis

Scientists may have a positive and potential effect in reduced risk and treatment of Non-Allergic Rhinitis, according to some studies.

Nonallergic rhinitis is a condition with symptoms resembles allergy induced rhinitis but without a known cause. However, some researchers suggested that environmental pollutants or odors, certain foods or beverages,,,,,,, and changes in the weather can trigger symptoms of the condition.

Some medications and underlying chronic health problems are associated with an increased risk of nonallergic rhinitis,

Most common symptoms are persistent sneezing, congestion, or a runny nose.

Chronic forms of rhinitis occurred in the absence of any detectable specific IgE against relevant allergens. In its broadest sense can be called chronic nonallergic rhinitis(1).

Long-term intake of medicine used for the treatment of nonallergic rhinitis such as nasal sprays containing an antihistamine may reduce symptoms of nonallergic rhinitis but can facilitate side effects of drowsiness or sleepiness, dizziness, dry mouth, nose, or throat,,,, increased appetite, weight gain, and upset stomach

In some cases, patients may experience, thickening of mucus, changes in vision, some psychological symptoms of nervousness, excited,... and irritable.

Cayenne is also known as Cayenne Pepper, a red, hot chili pepper, belongings to Capsicum annuum, the family Solanaceae, native to sub-tropical and tropical regions.

The herb has been used in traditional medicine to increases metabolism, enhance circulatory system and stomach and the intestinal tract, adjust blood pressure, lower LDL cholesterol and triglycerides, treat frostbite, muscles, arthritis, rheumatism, low back pain, strains, sprains, bruises, and neuralgia, etc.

Ingredients
The chemical constituents of Cayenne include capsaicin, capsacutin oil, solaine, xanthenes, oleic acid,.... and palmitic acid.


ICX72 or Sinus Buster, a proprietary homeopathic preparation of Capsicum annum, in the study of 42 consented subjects meeting inclusion/exclusion criteria randomized to ICX72 (n = 20) or control (n = 22) administered twice daily over 2 weeks, exhibited significant differences in changes from baseline and improvement in nasal congestion, sinus pain, sinus pressure, and headache, at 5, 10, 15, and 30 minutes, persisting at 60 minutes for nasal congestion and sinus pain inpatients with Nonallergic rhinitis(2).

Further analysis in concerns of the application adverse effects, researchers found that there is no difference between groups in adverse events in compared to placebo.

Dr. Bernstein JA, the lead author said, " ......intranasal capsaicin, when used continuously over 2 weeks, rapidly and safely improves symptoms in rhinitis subjects with a significant NAR component".

More importantly, ICX72 group experienced no rebound congestion or impaired olfaction in compared to placebo at the end of the study.

Moreover, in the study of 30 patients randomized into two different treatment regimens

* Group A received capsaicin five times on the first day at 1-h intervals, followed by a placebo dummy once every second or third day for a total of five treatments 2 weeks after the capsaicin application.

* Group B received the placebo dummy five times on the first day followed by capsaicin once every second or third day for a total of five treatments 2 weeks after the placebo application.

At the end of the experiment, researchers showed that

* Treatment group A reduced overall nasal symptoms, rhinorrhea, and nasal blockage, in compared to group B

* Both groups showed a significant reduction in cold dry air does responsiveness and nasal hyperreactivity. up to 9 months after therapy

* There were no No significant changes in safety data (smell, blood pressure, heart rate in group A in compared to group B.

Dr. Van Rijswijk JB, the lead scientist wrote, "....intranasal capsaicin seems safe to use and that five treatments of capsaicin on a single day is at least as effective as five treatments of capsaicin in 2 weeks".

The findings suggested that capsaicin may process the potential to cure nonallergic rhinitis.

However, large example size and multi-center clinical trials are necessary to reconfirm capsaicin anti nonallergic rhinitis validity.


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Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)

Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.


References
(1) Nonallergic rhinitis by Lieberman P1, Pattanaik D.(PubMed)
(2) A randomized, double-blind, parallel trial comparing capsaicin nasalspray with placebo in subjects with a significant component of nonallergicrhinitis by Bernstein JA1, Davis BP, Picard JK, Cooper JP, Zheng S, Levin LS.(PubMed)
(3) Intranasal capsaicin reduces nasal hyperreactivity in idiopathic rhinitis: a double-blind randomized application regimen study by Van Rijswijk JB1, Boeke EL, Keizer JM, Mulder PG, Blom HM, Fokkens WJ.(PubMed)