Sunday, November 29, 2015

Most Common Diseases of Ages of 50 Plus - Musculoskeletal disorders (MSDs): Fibromyalgia: The Causes and Risk Factors

Kyle J. Norton(Scholar)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
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Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

Musculoskeletal disorders (MSDs) is medical condition mostly caused by work related occupations and working environment, affecting patients’ muscles, joints, tendons, ligaments and nerves and developing over time. A community sample of 73 females and 32 males aged 85 and over underwent a standardised examination at home. Musculoskeletal pain was reported by 57% of those interviewed(1).

                      Fibromyalgia

According to the American College of Rheumatology 1990 Criteria for the Classification of Fibromyalgia in the newly proposed criteria for the classification of fibromyalgia are 1) widespread pain in combination with 2) tenderness at 11 or more of the 18 specific tender point sites(a) as a result in responding to pressure.

                            Causes and Risk factors  
   
A. Causes
1. Oxidative stress
There are some evidences demonstrating that oxidative stress is associated to clinical symptoms in FM of fibromyalgia(5).
2. Chronic stress
The relationship between stress, depression and functionality seems to be part of a complex mechanism, which might affect the quality of life of patients with FM(6).
3. Alpha1-Antitrypsin (AAT)
There is a a possible relationship between AAT deficiency (AAT-D) and fibromyalgia (FM)(7).
4. Inflammatory rheumatic disorders
There is evidence to suggest that fibromyalgia occurs much more frequently than expected in individuals with inflammatory rheumatic disorders(8).
5. Sleep disturbance
There is a reciprocal relationship exists between pain and sleep, and that intervention targeted primarily at insomnia may improve pain(9).
6. Etc.
B. Risk factors
1. Gender
If you are women, you are at higher risk than men to develop Fibromyalgia(10)
2. Family history
In the study to investigate whether Fibromyalgia (FM) patients differ from their first-degree relatives with and without FM regarding the four personality traits, based on Cloninger’s TPQ questionnaire, found that
relatives with FM display personality resemblance to FM patients especially in the personality trait harm avoidance. It appears that there are factors in this personality trait that are hereditary and that may contribute to the development of FM(11).
3. Environmental susceptibility may be the possible causes of Fibromyalgia(12).
4. Other illness
There is a believe that certain illness are associated to the increased risk of Fibromyalgia, such as diseases of infection.
5. Etc.

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