Diabetes is a medical condition caused by not insufficient insulin entering the bloodstream.
In other words, diabetes is a condition associated with the inability of the body to use insulin properly.
Most cases of insulin insufficiency in the bloodstream in diabetes are either caused by the gradual died-off of the pancreas beta cells or insulin receptors clogged-up by fat and cholesterol.
Hallmarks of diabetes are hyperglycemia and insulin resistance.
According to the statistics, in 2017, 7.3% of Canadians aged 12 and older (roughly 2.3 million people) reported being diagnosed with diabetes.
Most common causes of diabetes are metabolic syndrome, a cluster of conditions including high blood pressure, cholesterol, and glucose, gestational diabetes, prediabetes, damage to the pancreas causes the gradual and irreversible loss of beta cells that reduce the production of insulin, and influenza a viruses
Hypertension, a condition associated with the cluster of metabolic syndrome is a medical condition associated with abnormally high blood pressure.
Blood pressure is the force of blood pushing against the walls of the arteries as the heart pumps out blood and changes constantly depending on activity. However, persistent hypertension due to poor management over time can lead to diabetes and cardiovascular disease.
According to the statistics provided by the American Heart Association., nearly half of all adults in the United States are living with high blood pressure or 1 in 3 American are hypertensive.
Hypertension is leading risk factors of heart disease and stroke that cause most death in the US
The most common prevalent factors associated with the condition onset are family history, aging, being male, being overweight or obese, ethnicity, physical inactivity, unhealthy diet and medical condition such as chronic kidney disease.
Believe it or not, excessive alcohol drinking is also one of the major causes besides obesity in elevating the syndrome onset.
Cranberry is an evergreen dwarf shrub, genus Vaccinium, belongings to the family Ericaceae, native to Northern America and Southern Asia. Because of its health benefits, cranberry has been cultivated in some parts of the world for commercial profit and used in traditional and herbal medicine to treat wounds, urinary disorders, diarrhea, diabetes, stomach ailments, and liver problems.
On finding a potential compound for the management of blood pressure, researchers examined the effect of a water-soluble cranberry-based phytochemical combination with oregano, rosemary, and Rhodiola Rosea against hypertension.
According to the tested analysis, the 75% cranberry with 25% oregano combinations showed the highest antioxidant phenolics (38.9 mg/g DW) comapred to other combinations by inhibition of free radical DPPH inhibition by 73.6 %.
Furthermore, 75% cranberry and 25% Rhodiola Rosea combination had the highest alpha-glucosidase activity among the combinations.
Alpha-amyloid associated diabetes also was associated with 75% cranberry with 25% Rhodiola Rosea combination comapred to other combinations.
Additionally, anti-ACE-I inhibitory activity against the risk of hypertension was also inhibited by the 75% cranberry with 25% rosemary comapred to other combinations.
In other words, cranberry combined with other herbal medicine protects patients with diabetes and hypertension against complications by inhibiting the levels of alpha-glucosidase, alpha-amyloid, and ACE-I
Based on the results, researchers said, "The analysis of alpha-glucosidase,alpha-amylase, and ACE-I inhibitory activities suggested that inhibition depends on the phenolic profile of each unique extract and by bringing together synergistic combinations to cranberry, health beneficial functionality was enhanced".
Taken altogether, cranberry may be considered a remedy for the management of diabetes and hypertension, pending to the confirmation of the larger sample size and multicenter human study.
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Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Potential of cranberry-based herbal synergies for diabetes and hypertensionmanagement by Apostolidis E1, Kwon YI, Shetty K. (PubMed)
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