Medical Advisor Journals

Thursday, October 1, 2015

The effects of Phytochemicals against Bladder Cancer By Kyle J. Norton

Phytochemials are defined as a group of chemical compound found naturally in plants, including fruits, vegetables, beans, grains, etc.
Cancer is a class of diseases in which a group of cells growing and multiplying disordered and uncontrollable way in our body, have become progressively worse and damaged other healthy tissues, sometimes spreads to other organs in the body via lymph or blood and results in death.
Food intake can help to prevent and treat cancers. Many studies have proven that they can because of certain phytochemicals, but for what ever reason, there are either no clinical trials follow through or the studies can not make to stage of clinical trials. Do not expect the pharmateutical or foods industrial companies to pay for the researches, as the discovery of the phytochemicals to cure cancers can only dampen the profits of both industries as phytochemicals can not be patented.

I. Bladder cancers
A. The bladder is a hollow elastic organ in the center of the lower abdomen that collects urine from the kidneys and excreted them through the urethra.
Bladder cancer is most common type of cancer that effect men twice as frequently as it effects women. Usually it starts from the lining the bladder caused by several types of malignant growths of the urinary bladder cells.

B. Types of Bladder cancer
B.1. There are three types of bladder cancer beginning in cells in the lining of the bladder, classified due to their origination.
1. Transitional cell carcinoma
In early stage of bladder cancer, normal cells become cancerous in the innermost tissue layer of the bladder which can change shape and stretch without breaking apart as they are able to stretch when the bladder is full and shrink when it is emptied. More than 90 percent of bladder cancers begin in the transitional cells
2. Squamous cell carcinoma
Cancer begins in squamous cells in the found in the tissues of the surface of the bladder, due to long-term infection or irritation. About 8 percent of people with bladder cancers begin squamous cells
3. Adenocarcinoma
Cancer begins originates in glandular tissue of the bladder, including the surface layer of skin, glands and a variety of other tissue, due to long-term irritation and inflammation. Only 2 percent of people with the condition have a third bladder cancer type.

B. 2. Types of bladder cancer classified due to their proliferation
1. Superficial types of bladder cancer
This type of bladder cancers have a characteristic of often recurrence but usually non invasive. It can be controlled or removed by regular cystoscopy.
2. Invasive types of bladder cancer
Invasive types of bladder cancer tend to spread after beginning in cells in the lining of the bladder. It often requires surgery by removing part or whole bladder.

C. Types Foods Prevent and Treat Bladder cancer
1. Soy
Soy phytochemicals have been associated with the protective effect against bladder cancer as it contains genistein, and the isoflavone-rich soy phytochemical concentrate (SPC). Dr. Singh AV and the research team at the Beth Israel Deaconess Medical Center, showed that Mice treated with genistin and SPC had reduced final tumor weights by 56% (P < 0.05) and 52% (P < 0.05), respectively, associated with induction of tumor cell apoptosis and inhibition of tumor angiogenesis in vivo. In addition, SPC treatment, but not genistin treatment, significantly inhibited lung metastases by 95% (P < 0.01) associated with significant down-regulation of NF-kappaB expression in tumor tissues and reduction of circulating insulin-like growth factor-I levels, suggesting that SPC may contain other bioactive ingredients that have antimetastatic activity(1).

2. Milk thistle seed
Silybin, a phytochemical, is aslo known as Silibinin (INN), the major active ingredient of silymarin, a flavanone, found in the milk thistle seeds has been syudied for prevention and therapy of various human malignancies includingbladder. In the investigation of silibinin and it effect on bladder cancer found that oral silibinin suppressed the growth of 5637 xenografts, which was accompanied with the activation of caspase-3, downregulation of survivin, and increased translocation of AIF. Furthermore, intravesical silibinin effectively inhibited the carcinogenesis and progression of bladder cancer in rats initiated by MNU by reducing the incidence of superficial and invasive bladder lesions without any side effects, which was accompanied with proapoptotic effects.(7)

3. Cruciferous vegetables
Isothiocyanates are derived from the hydrolysis (breakdown) of glucosinolates—sulfur-containing compounds found in cruciferous vegetables. Isothiocyanates (ITCs) are a class of well-known cancerpreventive phytochemicals. Dr. Tang L and scientists at the Roswell Park Cancer Institute, in the sudy to examine the anti-cancer activity of NAC-ITCs in cultured human bladder cancer cells. In this paper, we report that the NAC conjugates of four naturally occurring ITCs, including allyl ITC, benzyl ITC (BITC), phenethyl ITC and sulforaphane, potently inhibited the growth of cells derived from both low-grade superficial and high-grade invasive humanbladder cancers and drug-resistant bladder cancer cells, indicated that both compounds also demonstrated the same anti-proliferative mechanisms: causing the cleavage of the same set of caspases (caspase-3, -8 and -9) in apoptosis induction, arresting cells in the same phases (S and G2/M) and targeting the same cell cycle regulator (Cdc25C), although a longer treatment time or slightly higher doses were needed for NAC-BITC to achieve the same effect as BITC, presumably due to slower cellular uptake of NAC-BITC. These data show that the NAC-ITCs are biologically similar to their parent compounds and are highly effective against human bladder cancer cells(3).

4. Garlic
Garlic components diallyl sulfide and diallyl disulfide on arylamine N-acetyltransferase have been exerted the protective effect against humanbladder tumor cells. Dr. Chung JG. at the China Medical College, in the study of Effects of garlic components diallyl sulfide and diallyl disulfide on arylamine N-acetyltransferase activity in human bladder tumor cells indicated that the viability, NAT activity and 2-AAF-DNA adduct formation in humanbladder tumor cells was inhibited by DAS and DADS in a dose-dependent manner, i.e. the higher the concentration of DAS and DADS, the higher the inhibition of NAT activity and cell death(4).

5. Cranberry juice concentration
In the study to exam the chemopreventive efficacy of cranberry juiceconcentrate in an experimental model of urinary bladder cancer, using female Fischer-344 rats, fed with N-butyl-N-(4-hydroxybutyl)-nitrosamine (OH-BBN) for a period of eight weeks, DR. Prasain JK and the reseah team at University of Alabama, showed that the cranberry extract neither affected body weight gain nor caused other signs of toxicity. For the metabolic studies, serum and urine were collected at 4 and 12 h after the administration of the cranberry juice concentrate and were analyzed by LC-MS/MS. Quercetin and its methylated derivative were detected in the urine samples. However, no quercetin was detected in the serum samples, indicating its poor bioavailability. These data suggest that components of cranberries may be effective in preventing urinary bladder carcinogenesis(5).

6. Green tea
The ingredient of (--)-Epigallocatechin-3-gallate (EGCG) in green tea have exerted the protective effect to cause bladder cancer cell death. "EGCGs that were physically attached onto the surface of nanogold particles (pNG) was confirmed by scanning electron microscopy. The anticancer activity of the EGCG-adsorbed pNG was investigated in C3H/HeN mice subcutaneously implanted with MBT-2 murine bladder tumor cells. EGCG-pNG was confirmed to inhibit tumor cell growing by means of cell apoptosis" said Dr.Hsieh DS and the research team team at National Taiwan Ocean University(6).

7. Tomato Juice
The ingredient of lycopene and other anti-oxidants in combination found abundantly in tomato juice have exerted an inhibitory effect on the development of TCCs in the rat urinary bladder. In the study of male Fischer 344 rats initiated with N-butyl-N-(4-hydroxybutyl)nitrosamine (BBN) in rats fed with 0.05% BBN in their drinking water for 8 weeks, followed by dilutedtomato juice for 12 weeks, lycopene concentrations in the livers of rats giventomato juice were elevated. Histopathological analysis of urinary bladderlesions revealed the numbers, but not incidences, of urinary bladdertransitional cell carcinomas (TCCs) to be decreased in the group giventomato juice(7).

8. Etc.

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References
(1) http://www.ncbi.nlm.nih.gov/pubmed/16452247
(2) http://www.ncbi.nlm.nih.gov/pubmed/21220495
(3) http://www.ncbi.nlm.nih.gov/pubmed/16520658
(4) http://www.ncbi.nlm.nih.gov/pubmed/10234471
(5) http://www.ncbi.nlm.nih.gov/pubmed/18497966
(6) http://www.ncbi.nlm.nih.gov/pubmed/21782236
(7) http://www.ncbi.nlm.nih.gov/pubmed/9510471

Party Cheese Ball

Recipe contributed by Quick and easy family favorites by Vickie and JoAnn

For a festive preservation roll up this flavorful mixture into 7 mini cheese balls as pictured opposite. for just one , proceed as directed in the recipe, rolling mixture into one large ball.
2 (8-oz.) pkgs. cream cheese, soften
2 c. shredded sharp Cheddar cheese
1 t. pimento, chopped
1 t. onion minced
1 t. lemon juice
1 t. green pepper chopped
2 t. Worcestershire sauce
1/8 cayenne pepper
1/8 t, salt
optional: chopped pecans
Bleen cream cheese until light and fluffy; and Cheddar cheese and next 7 ingredients. Shape into 7 mini balls(about one cup each); wrap into plastic wrap and refrigerate until firm. Roll in pecans, id desired
Make 7 mini balls

Sarah Sommers
Atwater, CA

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Wednesday, September 30, 2015

Most common diseases of Elders- Diseases of Central Nervous system(CNS): TCM Herbal treatments of Dementia Caused by Blood Stasis

C.4.1. Dementia due to Blood Stasis
According to Chinese medical literaure over 3000 years of history, blood Stasis may be caused by spleen qi deficiency, but in most cases, it is due to heart qi deficiency cause of inability in transport nutrients to the body organs and cells, including the brain. Prolong period of malnutrition of brain cells may induce abnormal function of brain's cells in information transmitting or death of neurons, cognitive impairments(844), including learning and memory deficits(842) and changes in brain tissues and behavior patterns(843)(842). Blood statsis induced by cold(1142), emotional disorder(1143), aging(1144), chronic illnesses and consumptive disease(1145), can overload the heart capacity, contributing to long-term hypertension(1146) due to decreased or impeded blood flow(1147) causes of hypo-perfusion in cerebral blood flow or acute focal stroke in memory-related cerebral parenchyma induced progression of cognitive decline(*).

Herbal medicine for treatment of Blood stasis
1. Wolfberry (Gou qi)
Gou Qi, the sweet and neutral herb is also known as wolfberry, used in TCM as anti cancers(1148)(1149), antioxidative(1150)(1151) and anti aging(1156)(1157) agent and to treat back, leg, and stomach pain(1152), hypopigmentation(1154), improve vision(1153)(1154), diabetes(1155), premature aging(1156), enhance immune system(1157), lower blood lipids(1158), elevate level of testosterone(1159), simulate estrogen and anti estrogen effect through different estrogen receptor mechanisms(1160) etc., as it nourishes and tonifies Liver and Kidneys, moistens the Lungs, etc., by enhancing the functions of liver, lung and kidney channels(1161).

Phytochemicals
1. Betaine
2. β-sitosterol
3. Linoleic acid
4. Physalien
5. Cryptoxanthin
6. Atropine
7. Hyoscyamine
8. Scopoletin
9. Amino acids
10. Physalein
11. Zeaxanthin
12. Dipalmitate
13. Carotene
14. Etc.

1.1. In Alzheimer's disease(AD)
Elevated plasma homocysteine (Hcy) levels have shown to be associated to increased the risk of Alzheime's disease (AD), epidemiologically and clinically. Polysaccharides, phytochemicals derived from wolfberry (LBA) not only inhibited Abeta accumulation but also reduced risk of other factors induced AD(1162). According to the University of Hong Kong, the chemical olysaccharides, also ameliorated glutamate excitotoxicity involved in many neurodegenerative diseases including Alzheimer's disease (AD)(1163). The herbal alkaline extract was found to exhibit neuroprotection, through inhibiting Abeta-peptides induced apoptosis and neuronal cell death(1164).

1.2. In neuroprotective effects
Lycium barbarum polysaccharide (LBP), on focal cerebral ischemic injury in mice model, inhibited neuronal morphological damage and attenuated the neuronal apoptosis through mitochondrial apoptosis pathway(1165). In ischemia-reperfusion-induced damage, chemical Lycium barbarum polysaccharides (LBP), reduced apoptosis and a decrease number of viable cells in the ganglion cell layer (GCL) and inner nuclear layer (INL), through its antioxidant activity(1166), In PC12 cell, Lycium barbarum extracts inhibited neurotoxin induced Parkinson's disease-like syndrome, through increased intracellular Ca (2+) level and significantly cell viability and cellular ATP levels(1167).

1.3. In cognitive impairment
In prenatal stress-induced cognitive impairment of offspring rats, Lycium barbarum showed to inhibit brain oxidative mitochondrial damage and cognitive dysfunction, through its scavenged hydroxyl and superoxide radicals(1168). Kyung-Ok-Ko (KOK), a traditional herbal prescription, containing Lycium, showed to enhance neuroprotective effects in attenuation of memory impairment, probably through its anti-inflammatory activities(1169).

1.4. In learning and memory
Lycium barbarum polysaccharides, scopolamine (SCO-induced cognitive and memory deficits in rats model, ameliorated and suppressed oxidative stress in hippocampus, and neurons apoptosis(1170). On transgenic mouse model of Alzheimer's disease, Gou qi extracts at 10 mg/kg improved the performance of the learning and the memory retrieval phases of tested models, through reduced levels of Aβ(1-42) in hippocampal tissue(1171). According to Kyung Hee University, Lycium chinense fruit, in trimethyltin (TMT)-induced neuronal and cognitive impairment rats model, improved learning and memory deficit in impaired learning and memory scores(1172).

2. Polygonum multiflorum (he shou wu)
He Shu Wu or Ye Jiao Teng or Shu Wu is also known as Fleece flower root or Fo-ti.
a. The prepared herb is astringent with some sweetness, mildly warm
b. The raw herb is bitter, sweet and neutral
used in TCM to treatment of hyperlipemia(1173), neurasthenia(1174), split personality(1174), promoted hair grown(1175) and prevent hair loss(1176) due to aging, skin rash due to inflammation(1177), etc., as the herb tonifies and benefits the essence and blood, expels toxins, moistens the intestines, etc. by enhancing the (The prepared herb) liver and kidney channels and (The raw herb) liver, heart and large intestine channels(1178).

Phytochemicals
1. Polygoacetophenoside

2. Chrysophanol
3. Emodin
4. Rhein
5. Emodin-6
6. Physcion
7. Chrysophanic acid
8. Anthrone
9. beta-sitosterol
10. 2,3,5,4′-tetrahydroxystibene-2O-b-D-glucoside
11. Quercetin-3-O-galactoside
12. Querctin-3-O-arabinoside
13. Lecithin
14. Etc.

1. In Alzheimer's disease
Polygonum multiflorum extract, showed to significantly improved AD patients with total effective rate of 93.33% in clinical trial, according to Third Xiangya Hospital(1179). In rat model, induced Alzheimer's disease by injecting Abeta 1-40, exhibited improvement of learning and memory ability, through expression of the fluidity of mitochondria membrane and the activity of mitochondrial COX(1180) and ameliorated hippocampal synapses count and synaptophysin expression(1181). In cognitive deficits induced by Abeta25-35, Polygonum multiflorum Thunb water extract, also significantly ameliorated the cognitive deficits, probably due to its antioxidant properties(1182).

2. In Parkinson disease
Strong evidences suggested that agricultural chemicals and environment toxins, such as dithiocarbamate fungicides such as manganese ethylenebisdithiocarbamate [maneb (MB)], impact dopamine systems has shown to associate to the development of Parkinson's disease,(1184)(1185)
In nigrostriatal dopaminergic degeneration induced by paraquat and maneb in mice model, ethanol-soluble PME (PME-I) water extracts from Polygonum multiflorum, showed to improve locomotor activity, motor incoordination, and declines of dopamine level, probably through phytochemicals, in the ethanol-soluble fraction of PME (PME-I)(1183).

3. In neuroprotective effects
In focal cerebral ischemia in mice, hexane extracts of Polygonum multiflorum, exhibited its neuroprotective effects though significantly decreased infarct size and improved neurological and motor function, (1186) and decreased glutamate-induced neurotoxicity in a concentration-dependent manner and prevention of apoptosis of cortical neurons(1187), in HT22 hippocampal cells(1188), probably through it antioxidant activity. According to Xuanwu Hospital of Capital Medical University, 2,3,5,4'-tetrahydroxystilbene-2-O-β-D-glucoside (TSG) extracted from Polygonum multiflorum, also improved mitochondrial function, decreased oxidative stress and inhibited apoptosis against induced cytotoxicity in human dopaminergic neuroblastoma SH-SY5Y cells(1188).

4. In learning and memory
Dietary supplementation with either ethanol or water extracts of Polygonum multiflorum has shown to reduce brain pathological changes and promote learning and memory ability(1191)(1192). In male Sprague-Dawley rats, injected with beta amyloid (Aβ), tetrahydroxystilbene glucoside, an active chemical constituent of extract from Polygonum multiflorum, significantly improved the learning and memory, through by protecting synaptic structure and function(1189) and learning and/or memory ability of aged rats by increased Beta-secretase 1 (BACE1), a beta-site amyloid precursor protein cleaving enzyme 1 and decrease ADAM10 (metallopeptidase domain 10), a protein associated to the development of Alzheimer's disease(1190).

For other Healthy Kid loved recipes http://kylejnorton.blogspot.ca/p/recipes.html
Super foods Library, Eat Yourself Healthy With The Best of the Best Nature Has to Offer

Reprinted from Norton Journal, Volume I, Most Common Diseases of Ages of 50 Plus - Chapter of Diseases of Central Nervous system(CNS): Dementia caused by Blood Stasis - Treatments in Traditional Chinese Herbal Medicine by Kyle J. Norton.

References
(*) http://www.hindawi.com/journals/ecam/2012/692621/
(842) http://www.ncbi.nlm.nih.gov/pubmed/25313575
(843) http://www.ncbi.nlm.nih.gov/pubmed/24224039
(844) http://www.ncbi.nlm.nih.gov/pubmed/23391905
(1142) http://www.ncbi.nlm.nih.gov/pubmed/24288569
(1143) http://www.classicalchinesemedicine.org/2010/03/blood-blood-stasis-and-blood-path-disorders/
(1144) http://www.goodreads.com/book/show/2250018.Aging_Blood_Stasis
(1145) http://www.tcvm.com/NewsArticles/TabId/245/ArtMID/1382/ArticleID/97/A-Look-at-Blood-Stasis.aspx

(1146) http://www.ncbi.nlm.nih.gov/pubmed/25412665

Super Nachos

Recipe contributed by Quick and easy family favorites by Vickie and JoAnn

Keep these simple ingredients around for a quick & easy snack the whole family will enjoy
2 (10-inch) flour tortillas
3/4 c. salsa
4.5-oz. can green chiles, drained and diced
1/2 c. sliced black olives
1 c. shredded Monterey Jack cheese
Place tortilla on an ungreased baking sheet: spread salsa over tortilla.prinkle chiles and olives over salsa; top with cheese.
bake at 425 degrees for 10 minutes or until tortillas are crisp and cheese is melted. Use a pizza cutter to slice each into 8 wedges.
Make 8 appetizer servings

Mary Murray
Gooseberry Patch

Ovarian Cysts And PCOS Elimination
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Using Holistic Ancient Chinese Medicine

Tuesday, September 29, 2015

Most common diseases of Elders- Diseases of Central Nervous system(CNS): TCM herbal Shui Fei Zi (Milk thistle) treatments of Dementia Caused by Toxin Accumulation

Weight Loss the Easy Ways
Andrea Albright Featured on Health and Fitness Jan. 2015
will Personally Coach You How to Get There The Easy Way

If You Are Looking For a SoulMate
Celebrity Patti Stanger Will Coach You To Get Him/Her
and Keep Him/Her for Good,The Simple Way

By Kyle J. Norton Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

Diseases of Central Nervous system

Dementia

About 5-8% of all people over the age of 65 have some form of dementia, and this number doubles every five years above that age. Dementia is the loss of mental ability, severe enough to interfere with people's every life and Alzheimer's disease is the most common type of dementia in aging people.
V. Treatments
C. In traditional Chinese Medicine Perspective(*)
Based on Chinese ancient medical records. causes of dementia are the results of (*)

C.5. According to TCM philosophy, dementia is also to be induced by the combination/or of Kidney essence vacuity and toxin (turbid phlegm).
C.5.1. Dementia due to toxins accumulation
Toxins accumulation in internal organs disturbed the balance of immunity(1213)(1214) may cause impairment of food intake regulation(1215), exhibition of phlegm(1208)(1208)(1210), retention of fluid(1211)(1212) and blood statsis(1209) induced early the onset of dementia, in aging population with depletion of kidney-essence(1208)(1209), according to traditional Chinese medicine.

Herbal Medicine for toxins elimination
Chinese Herbal medicine for toxins elimination
1. Shui Fei Zi or Milk thistle (Silybum marianum)
Shui fei zi, the bitter and cold herb, is also known as milk thistle, native to Western Europe and northern Africa, used in traditional Chinese medicine to improve liver function(1193)(1194)(1210), promote the flow of breast milk(1207), bile secretion(1200), anti depression(1201) and anti tumors(1196)(1197)(1198), inhibit allergic effects(1195)(1199), treat hepatitis C(1202)(1203), cirrhosis(1205) and liver fibrosis(1206), by enhancing function of liver and gallbladder channels(1204)

Phytochemicals
1. Flavonoid
2. Fumaric acid
3. Silymarin
4. Isosilybin,
5. Dehydrosilybin,
6. Silydianin
7. Silychristin
8. Cinnamic acid
9. Myristic acid
10. Palmitelaidic acid
10. Arachidic acid
11. Etc.

Shui Fei Zi or Milk thistle used in the treatment and prevention of dementia(1218) in traditional Chinese medicine, may be due to its effectiveness of phytochemicals Silymarin and Silibinin in ameliorated amyloid pathology(1216) and oxidative stress(1216)(1217) through attenuated levels of lipid peroxidation (malondialdehyde) and antioxidant (glutathione) in the hippocampus(1217).

1.1. In Alzheimer's disease
Alzheimer disease (AD). a neurodegenerative disorders is the most prevalent diseases in the United States, in aging population(1219). Silymarin, a phytochemical found abundantly in milk thistle, in age related disorders like neurodegenerative diseases improved locomotion rate, higher response to stimuli and tolerance to stress, in C.elegans Alzheimer's Model, through delayed paralysis via enhanced resistance to oxidative stress(1220). In rat induced Alzheimer's disease model, the phytochemical also inhibited amyloid formation(1222) and suppressed amyloid protein precursor (APP) expression(1222)and reduced neurotoxicity in PC12 cells(1222) in improvement memory(1223) and learning function(1221).

1.2. In Parkinson disease
In a mouse model of Parkinson's disease, causes of mitochondrial dysfunction and selective cells death of dopaminergic neurons, silibinin, derivative of silymarin, protected mitochondria through attenuated motor deficit and dopaminergic neuronal loss(1224) and anti oxidative and anti inflammatory pathways(1225).

1.3. In neuroprotective effects
In focal cerebral ischemia, silymarin (SM), a mixture of flavonolignans extracted from the milk thistle exerted it neuroprotective effects, in upregulating the antioxidant status and lowering the apoptotic response in slowing down the progression of neurodegeneration(1226) and preventing inflammation-related neurodegenerative disease(1227) and ROS causs of oxidative damage to macromolecules in the brain(1230).

1.4. In cognitive impairment
In cognitive deficit mice model, silibinin exhibited its anti cognitive impairment effects through amelioration of decreases in dopamine and serotonin levels in the prefrontal cortex and hippocampus, (1228). In amyloid beta peptide-induced memory impairment, the chemicals also improve cognitive memory deficits through attenuated the Abeta(25-35)- accumulation of malondialdehyde and depletion of glutathione in the hippocampus(1229).

Reprinted from Norton Journal, Volume I, Most Common Diseases of Ages of 50 Plus - Chapter of Diseases of Central Nervous system(CNS): Dementia - Treatments in Traditional Chinese Herbal Medicine by Kyle J. Norton.

Super foods Library, Eat Yourself Healthy With The Best of the Best Nature Has to Offer

References
(*) http://www.hindawi.com/journals/ecam/2012/692621/
(1193) http://www.ncbi.nlm.nih.gov/pubmed/9468229
(1194) http://www.ncbi.nlm.nih.gov/pubmed/20564545
(1195) http://www.ncbi.nlm.nih.gov/pubmed/23121838
(1196) http://www.ncbi.nlm.nih.gov/pubmed/23879966
(1197) http://www.ncbi.nlm.nih.gov/pubmed/24574320
(1198) http://www.ncbi.nlm.nih.gov/pubmed/25242120
(1199) http://www.ncbi.nlm.nih.gov/pubmed/23701595
(1200) http://www.ncbi.nlm.nih.gov/pubmed/17692492
(1201) http://www.ncbi.nlm.nih.gov/pubmed/25431050
(1202) http://www.ncbi.nlm.nih.gov/pubmed/25247194
(1203) http://www.ncbi.nlm.nih.gov/pubmed/22797645
(1204) http://alternativehealing.org/shui_fei_ji.htm
(1205) http://www.ncbi.nlm.nih.gov/pubmed/15277093
(1206) http://www.ncbi.nlm.nih.gov/pubmed/22087179
(1207) http://www.ncbi.nlm.nih.gov/pubmed/23468043
(1208) http://www.ncbi.nlm.nih.gov/pubmed/24187864
(1209) http://www.ncbi.nlm.nih.gov/pubmed/22500712
(1210) http://www.ncbi.nlm.nih.gov/pubmed/24155069
(1211) http://www.ncbi.nlm.nih.gov/pubmed/25155658
(1212) http://www.ncbi.nlm.nih.gov/pubmed/25162367
(1213) http://www.ncbi.nlm.nih.gov/pubmed/24719080
(1214) http://www.ncbi.nlm.nih.gov/pubmed/22866982
(1215) http://www.ncbi.nlm.nih.gov/pubmed/16769094
(1216) http://www.ncbi.nlm.nih.gov/pubmed/21185897
(1217) http://www.ncbi.nlm.nih.gov/pubmed/19552690
(1218) http://www.ncbi.nlm.nih.gov/pubmed/21071836
(1219) http://www.ncbi.nlm.nih.gov/pubmed/25696782
(1220) http://www.ncbi.nlm.nih.gov/pubmed/25613505
(1221) http://www.ncbi.nlm.nih.gov/pubmed/24460990
(1222) http://www.ncbi.nlm.nih.gov/pubmed/21071836
(1223) http://www.ncbi.nlm.nih.gov/pubmed/19638571
(1224) http://www.ncbi.nlm.nih.gov/pubmed/25677261
(1225) http://www.ncbi.nlm.nih.gov/pubmed/24660866
(1226) http://www.ncbi.nlm.nih.gov/pubmed/21840019
(1227) http://www.ncbi.nlm.nih.gov/pubmed/20833521
(1228) http://www.ncbi.nlm.nih.gov/pubmed/19857526
(1229) http://www.ncbi.nlm.nih.gov/pubmed/19552690
(1230) http://www.ncbi.nlm.nih.gov/pubmed/19647779

Hot Chili Cheese

Recipe contributed by Quick and easy family favorites by Vickie and JoAnn

Be sure to know this hearty dip on your menu the next time family & friends are over to watch the big game..... it will be a hit.
1 lb. mild or spicy ground pork sausage, browned and drained
2 (103/4-oz. cans nacho cheese soup
15-oz. can chili with beans
141/2 oz. can tomatoes with chiles
16-oz. pkg. pasteurized process cheese spread, cubed
Combine all ingredients except cheese in a large saucepan over medium heat; cook until bubbly. Add cheese. Reduced heat; cook and stir until cheese is completely melted.
Make 6 to 7 cups.

David Wink
Gooseberry Patch

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Pregnancy Miracle
Reverse Infertility And Get Pregnant Naturally
Using Holistic Ancient Chinese Medicine

Monday, September 28, 2015

Most common diseases of Elders- Diseases of Central Nervous system(CNS): TCM herbal Xiu Hui Xiang (Fennel) treatments of Dementia Caused by Toxin Accumulation

Weight Loss the Easy Ways
Andrea Albright Featured on Health and Fitness Jan. 2015
will Personally Coach You How to Get There The Easy Way

If You Are Looking For a SoulMate
Celebrity Patti Stanger Will Coach You To Get Him/Her
and Keep Him/Her for Good,The Simple Way

By Kyle J. Norton Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

Diseases of Central Nervous system

Dementia

About 5-8% of all people over the age of 65 have some form of dementia, and this number doubles every five years above that age. Dementia is the loss of mental ability, severe enough to interfere with people's every life and Alzheimer's disease is the most common type of dementia in aging people.
V. Treatments
C. In traditional Chinese Medicine Perspective(*)
Based on Chinese ancient medical records. causes of dementia are the results of (*)

C.5. According to TCM philosophy, dementia is also to be induced by the combination/or of Kidney essence vacuity and toxin (turbid phlegm).
C.5.1. Dementia due to toxins accumulation
Toxins accumulation in internal organs disturbed the balance of immunity(1213)(1214) may cause impairment of food intake regulation(1215), exhibition of phlegm(1208)(1208)(1210), retention of fluid(1211)(1212) and blood statsis(1209) induced early the onset of dementia, in aging population with gradual depletion of kidney-essence(1208)(1209), according to traditional Chinese medicine.

Herbal Medicine for toxins elimination
Chinese Herbal medicine for toxins elimination
2. Xiu Hui Xiang (Fennel)
Xiu Hui Xiang, the acrid and warm herb, is also known as fennel, native to Mediterranean, used in traditional Chinese medicine as anti microbal(1232)(1233), antioxidant(1234)(1235) and emmenagogue(1236) and estrogenic(1244) and androgenic(1245) agents and to prevent bone loss in postmenopausal osteoporosis(1237)(1238), treat hepatic fibrosis(1239), gastro intestine disorder(1240)(1241), decrease hair thickness(1243) and increase flow of breast milk(1242) by enhancing function of liver, kidney, spleen, stomach channels(1231).

Phytoshemicals
1. Linoleic acid
2. Palmitic acid
3. Arachidic acid
4. Behenic acid
5. Quercetin
6. Phytosteryl b-fructofuranoside
7. 7-hydroxycoumarin
8. 6,7-dihydroxycoumarin
9. Oleanolic acid
10. Sitosterol
11. Fenchone
12. α-pinene
13. Limonene
14. β-Pinene
15. β-Myrcene
16. α-Phellandrene
17. P-Cymol
18. Etc.

Xiu Hui Xiang (Fennel) used in the treatment of symptoms of neurodegenerative disorder, including age-related mental problems of Alzheimer's disease(1246)) in traditional Chinese medicine, may be due to its effectiveness of phytochemicals in acetylcholinesterase inhibition(1246) and anti inflammation(1247) through suppression of the nuclear factor-kappaB activation pathway(1247) involved stress, cell signaling, free radicals, oxidized LDL,activities(1248)(1249)(1250)(1251).

1. In anxiolytic activity
Anxiety is a condition of neurodisorder of unpleasant state of inner turmoil with fear of the presence and future, according to Diagnostic and Statistical Manual of Mental Disorders American Psychiatric Association, effecting patients with dementia, included familial Alzheimer's disease(1252) and other neuropsychiatric disorders(1254). Fennel, a medical herb used in many cultures, have shown effectively in treating anxiety, epidemiologically. In adult Swiss albino male mice, oral administration 100 and 200 mg/kg doses of fennel essential oil significantly increased percent number of entries and time spent in open arms in elevated plus maze (EPM) test(1255).

2. In learning and memory
Fennels, the most widely used herbal plant in the world(1256) used in traditional Iranian medicine and modern phytotherapy for memory enhancing(1257). In Alzheimer's disease, induced a decline of cognitive abilities in mice model, fennel extract successfully ameliorated the amnesic effect of scopolamine (0.4 mg/kg) and aging- induced memory deficits in 8 days in dose-depend manner, through increased step-down latency and acetylcholinesterase inhibition(1258).

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References
(*) http://www.hindawi.com/journals/ecam/2012/692621/
(1208) http://www.ncbi.nlm.nih.gov/pubmed/24187864
(1209) http://www.ncbi.nlm.nih.gov/pubmed/22500712
(1210) http://www.ncbi.nlm.nih.gov/pubmed/24155069
(1211) http://www.ncbi.nlm.nih.gov/pubmed/25155658
(1212) http://www.ncbi.nlm.nih.gov/pubmed/25162367
(1213) http://www.ncbi.nlm.nih.gov/pubmed/24719080
(1214) http://www.ncbi.nlm.nih.gov/pubmed/22866982
(1215) http://www.ncbi.nlm.nih.gov/pubmed/16769094
(1231) http://alternativehealing.org/xiao_hui_xiang.htm

(1232) http://www.ncbi.nlm.nih.gov/pubmed/25384804
(1233) http://www.ncbi.nlm.nih.gov/pubmed/21462837
(1234) http://www.ncbi.nlm.nih.gov/pubmed/21812646
(1235) http://www.ncbi.nlm.nih.gov/pubmed/25143939
(1236) http://www.ncbi.nlm.nih.gov/pubmed/?term=fennel+emmenagogue
(1237) http://www.ncbi.nlm.nih.gov/pubmed/22447109
(1238) http://www.ncbi.nlm.nih.gov/pubmed/25050267
(1239) http://www.ncbi.nlm.nih.gov/pubmed/22475144
(1240) http://www.ncbi.nlm.nih.gov/pubmed/22433535
(1241) http://www.ncbi.nlm.nih.gov/pubmed/20433751
(1242) http://www.ncbi.nlm.nih.gov/pubmed/6999244
(1243) http://www.ncbi.nlm.nih.gov/pubmed/24490010
(1244) http://www.ncbi.nlm.nih.gov/pubmed/6999244
(1245) http://www.ncbi.nlm.nih.gov/pubmed/13678227
(1246) http://www.ncbi.nlm.nih.gov/pubmed/?term=fennel+dementia
(1247) http://www.ncbi.nlm.nih.gov/pubmed/15659827
(1248) http://www.nature.com/onc/journal/v25/n51/full/1209954a.html
(1249) http://link.springer.com/article/10.1385%2FCT%3A6%3A2%3A111
(1250) http://www.ncbi.nlm.nih.gov/pubmed/10602459
(1251) http://www.nature.com/nrm/journal/v8/n1/full/nrm2083.html
(1252) http://www.ncbi.nlm.nih.gov/pubmed/25688083
(1253) http://www.ncbi.nlm.nih.gov/pubmed/25687925
(1254) http://www.ncbi.nlm.nih.gov/pubmed/25653291
(1255) http://www.ncbi.nlm.nih.gov/pubmed/?term=fennel+and+anxiety
(1256) http://www.ncbi.nlm.nih.gov/pubmed/25162032
(1257) http://www.ncbi.nlm.nih.gov/pubmed/23275017