The Smoothie of Cooked Tomato, Carrot and Green tea for reduced risk and treatment of Endometrial Cancer

Kyle J. Norton(Scholar)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

The smoothie for reduced risk and treatment of endometrial cancer

Yield: 2 serving (about 8 ounce each)
1 1/4 cup cooked tomato
1/4 cup carrot
1 cup green tea drink (Make from 4 grams of green tea and a cup of hot water lipped for 5 minutes, and set aside for cooling to room temperature)


1. Place all ingredients in a blender and puree about 1 minute
2. Blend on high speed about 1 minute or until the mixture is thick and the ice is well crushed. Add more green tea drink if needed
3. Serve immediately

The dream of finding the natural ingredient for prevention and treatment of endometrial cancer  without adverse effects in replacement of conventional medication has not been abated. Some ingredients have to discard due to it can achieve the same potent results in human trials.
Green tea(1) and carrot, tomato(4) may have a potential and therapeutic value for reduced risk and treatment of cervical cancer probably due to theirs' phytochemicals effect in ameliorated proliferation of cancer cell expression, recent studies suggested.

In a total of 995 incidence cases aged 30 - 69 from January 1997 to December 2002 and 1087 controls, Green tea consumption has shown an inverse association with endometrial cancer risk(1).
According to the First People's Hospital of Changde City study, Overall relative risk (RR) suggested that increased green tea consumption was associated with a reduced risk of endometrial Cancer, but large population-based randomized controlled trials and large prospective cohort studies are required to obtain a definitive conclusion and determine the mechanisms underlying this association(2).
Other study insisted that the inverse association of endometrial cancer risk with caffeinated coffee intake was specific to women with a body mass index 30+ kg m(3).

Tomato, a red, edible fruit, genus Solanum, belongings to family Solanaceae, native to South America may have a potential use for reducing risk and treatment of endometrial cancer(4). According to the Istituto di Ricerche Farmacologiche Mario Negri, dietary carotenoids forms a favorable role of reduced risk on endometrial cancer(4). and blood serum levels of beta-carotene are inversely associated with the risk of endometrial cancer in Korean women(5).

Lycopene, another phytochemical found in tomato and carrot also exhibited anti endometrial cancer activity through inhibiting cell proliferation associated with inhibition of cell cycle progression at the G(1) phase(6).

Dr. Hirsch K and the research team at the Ben-Gurion University of the Negev and Soroka Medical Center of Kupat Holim said," carotenoids prevent several types of cancer, including mammary and endometrial cancers" and " dietary carotenoids inhibit estrogen signaling of both 17beta-estradiol and genistein, and attenuate their deleterious effect in hormone-dependent malignancies"(7).

Women who are at high risk of endometrial cancer such as genetic mutation genes,,.....should drink at least one cup daily and people with endometrial cancer should drink the juices as much as they can depending to digestive toleration.

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You Can Eliminate Osteoarthritis
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References

(1) [Green tea consumption and the risk of endometrial cancer: a population-based case-control study in urban Shanghai].[Article in Chinese] by Gao J1, Xiang YB, Xu WH, Shao CX, Ruan ZX, Cheng JR, Shu XO, Gao YT.(PubMed)

(2) Green tea, black tea consumption and risk of endometrial cancer: a systematic review and meta-analysis by Zhou Q1, Li H, Zhou JG, Ma Y, Wu T, Ma H.(PubMed)

(3) Intake of coffee, caffeine and other methylxanthines and risk of Type I vs Type II endometrial cancer by Uccella S1, Mariani A, Wang AH, Vierkant RA, Cliby WA, Robien K, Anderson KE, Cerhan JR.(PubMed)

(4) The U.S. Food and Drug Administration's evidence-based review for qualified health claims: tomatoes, lycopene, and cancer by Kavanaugh CJ1, Trumbo PR, Ellwood KC.(PubMed)

(5) Preoperative levels of plasma micronutrients are related to endometrial cancer risk by Jeong NH1, Song ES, Lee JM, Lee KB, Kim MK, Yun YM, Lee JK, Son SK, Lee JP, Kim JH, Hur SY, Kwon YI.(PubMed)

(5) Preoperative levels of plasma micronutrients are related to endometrial cancer risk by Jeong NH1, Song ES, Lee JM, Lee KB, Kim MK, Yun YM, Lee JK, Son SK, Lee JP, Kim JH, Hur SY, Kwon YI.(PubMed)

(6) Lycopene inhibition of cell cycle progression in breast and endometrial cancer cells is associated with reduction in cyclin D levels and retention of p27(Kip1) in the cyclin E-cdk2 complexes by Nahum A1, Hirsch K, Danilenko M, Watts CK, Prall OW, Levy J, Sharoni Y.(PubMed)

(7) Lycopene and other carotenoids inhibit estrogenic activity of 17beta-estradiol and genistein in cancer cells by Hirsch K1, Atzmon A, Danilenko M, Levy J, Sharoni Y.(PubMed)

Most Common Diseases of elder: Respiratory Disease: Asthma Treatment: The Effectiveness of Vitamin E

Kyle J. Norton(Scholar and Master of Nutrients)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

Respiratory Disease is defined as medical conditions which affect the breathing organ and tissues including Inflammatory lung disease, Obstructive lung diseases, Restrictive lung diseases, Respiratory tract infections, trachea, bronchi, bronchioles, alveoli, the nerves and muscles breathing , etc,.

                                  Asthma

Asthma is a chronic inflammatory disease affecting the air way of the lung with recurring symptoms, such as wheezing, chest tightness, shortness of breath, and coughing. The disease affects people of all ages, and mostly starts during childhood. In the study of 463,801 children aged 13-14 years in 155 collaborating centres in 56 countries. Children self-reported, through one-page questionnaires, symptoms of these three atopic disorders. In 99 centres in 42 countries, a video asthma questionnaire was also used for 304,796 children, found that for asthma symptoms, the highest 12-month prevalences were from centres in the UK, Australia, New Zealand, and Republic of Ireland, followed by most centres in North, Central, and South America; the lowest prevalences were from centres in several Eastern European countries, Indonesia, Greece, China, Taiwan, Uzbekistan, India, and Ethiopia(1). In the United States, approximately, asthma affects 25 million people, 7 million of them are children.

                   The Effectiveness of Vitamin E

Vitamin E, a fat soluble vitamin, consisting eight different variants (alpha-, beta-, gamma-, and delta-tocopherol and alpha-, beta-, gamma-, and delta-tocotrienol) with varying levels of biological activity(2), found abundantly in corn oil, soybean oil, margarine, wheat germ oil, sunflower,safflower oils, etc. plays an important role in neurological functions and inhibition of platelet aggregation, regulation of enzymatic activity, free radical scavenger, etc..
General consensus suggestion of increased dietary vitamin E intake is associated with a reduced incidence of asthma, due its antioxidant status, but epidemiological studies, linking vitamin E in reduced risk and treatment of asthma have not been conclusive(a)(b)(c)(d)(e).

1. Serum levels of vitamin E
Serum levels of vitamin in asthmatic patients may be correlated to the occurrence of the diseases. The University of Tampere study of five European rural settings with Children of 1133 mothers recruited during pregnancy, showed no associated of with allergies or asthma by 6 years of age regardless the concentration of vitamin E(1). and the study of the Yamaguchi University, also indicated no correlation of levels of vitamin E and asthma in the a total of Of 2796 students attending schools in Shunan, Japan, in 2006.(1a). The University of Medical Sciences study indicated other wise as treatment of fluticasone and vitamin E (50mg/day) showed an significantly increased of Serum level of Vitamin E, with improved FEV1 and FEV1/FVC ratio(2). The study of acute asthmatic attack in children, showed a high degree of reactive oxygen species formation causing considerable oxidative stress with the high level of oxidants Serum malondialdehyde (MDA) and low level of antioxidants(vitamin C, vitamin E and uric acid)(3). Researchers at the Oslo University Hospital, in the study of children of 7-12 yr with asthma (n = 50) and no asthma (controls) (n = 52)indicated that schoolchildren with asthma and rhinitis had reduced levels of the major serum antioxidant albumin, and poorly controlled asthma was associated with decreased vitamin E and transferrin levels(4).


2. The effects
The Northwestern University study indicated the opposing regulatory effects as allergic inflammation is inhibited by supplementation with the purified natural vitamin E isoform α-tocopherol but elevated by the isoform γ-tocopherol when administered at physiological tissue concentrations(5)(6). But according to University of North Carolina School of Medicine, γ-tocopherol (GT) significantly decreased (p < 0.05) internalization of attached zymosan bioparticles and macrophage expression of CD206, CD36 and CD86 in allergic asthmatics through downregulation of both innate and adaptive immune response elements, and atopic status(7). The composition containing 623 mg of gamma-tocopherol, 61.1 mg of d-alpha-tocopherol, 11.1 mg of d-beta-tocopherol (11.1 mg), and 231 mg of d-sigma-tocopherol capsule in Phase I human dosing study showed the decreased systemic oxidative stress, increased serum levels of gamma-tocopherol, and inhibited monocyte responses to LPS without any adverse health effects(8). IOvalbumin (OVA)-sensitized Brown Norway rats, treatment of gamma-tocopherol (gammaT), inhibited the pathogenesis of both AR and asthma inflammatory pathways(9).Suggestion of oxidant stress and diminished antioxidant defenses may be a cause of asthmatic disease(10) and uncontrolled asthma and severe asthmapattern have impaired antioxidant defenses and are thus most susceptible to the damaging effects of oxidative stress(11). 1500 IU of natural-source d-α-tocopheryl acetate daily for at least 16 weeks in volunteered asthmatic patient, showed to inhibited oxidant stress, through modulation of allergic inflammation and airway hyperresponsiveness in human atopic asthmatics in vivo(12).

Taken altogether, Aγ-tocopherol, a variant of vitamin E, may be effective in reduced risk and treatment of asthmatic disorder, but further large sample and in multi centers studies are necessary to validate it claims. Over doses of vitamin E supplement can cause symptoms of blurred vision, weakness, dizziness, nausea, diarrhea, etc., please make sure you follow the guideline of the Institute of Medicine of the National Academies.


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You Can Eliminate Osteoarthritis
By addressing the Underlying Causes through Clinical Trials and Studies

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

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References
(a) Vitamin E supplements in asthma: a parallel group randomised placebo controlled trial by Pearson PJ1, Lewis SA, Britton J, Fogarty A(PubMed)
(b) Effects of vitamin E on mitochondrial dysfunction and asthma features in an experimental allergic murine model by Mabalirajan U1, Aich J, Leishangthem GD, Sharma SK, Dinda AK, Ghosh B.(PubMed)
(c) Diet and asthma: vitamins and methyl donors by Han YY1, Blatter J1, Brehm JM1, Forno E1, Litonjua AA2, Celedón JC3.(PubMed)
(d) Asthma, allergy, and responses to methyl donor supplements and nutrients by Sharma S1, Litonjua A(PubMed)
(e) Vitamin e supplementation, lung functions and clinical manifestations in children with moderate asthma: a randomized double blind placebo- controlled trial by Ghaffari J1, Farid Hossiani R, Khalilian A, Nahanmoghadam N, Salehifar E, Rafatpanah H.(PubMed)
(1) Serum vitamin E concentrations at 1 year and risk of atopy, atopic dermatitis, wheezing, and asthma in childhood: the PASTURE study by Nwaru BI1, Virtanen SM, Alfthan G, Karvonen AM, Genuneit J, Lauener RP, Dalphin JC, Hyvärinen A, Pfefferle P, Riedler J, Weber J, Roduit C, Kaulek V, Braun-Fahrländer C, von Mutius E, Pekkanen J; PASTURE study group.(PubMed)
(1a) Association of serum carotenoids and tocopherols with atopic diseases in Japanese children and adolescents by Okuda M1, Bando N, Terao J, Sasaki S, Sugiyama S, Kunitsugu I, Hobara T.(PubMed)
(2) Vitamin e supplementation, lung functions and clinical manifestations in children with moderate asthma: a randomized double blind placebo- controlled trial by Ghaffari J1, Farid Hossiani R, Khalilian A, Nahanmoghadam N, Salehifar E, Rafatpanah H.(PubMed)
(3) Antioxidant status in acute asthmatic attack in children by Al-Abdulla NO1, Al Naama LM, Hassan MK.(PubMed)
(4) Altered oxidative state in schoolchildren with asthma and allergic rhinitis by Bakkeheim E1, Mowinckel P, Carlsen KH, Burney P, Carlsen KC.(PubMed)
(5) Vitamin E isoforms as modulators of lung inflammation by Abdala-Valencia H1, Berdnikovs S, Cook-Mills JM.(PubMed)
(6) Two faces of vitamin E in the lung by Cook-Mills JM1, Abdala-Valencia H, Hartert T.(PubMed)
(7) Effects of ex vivo γ-tocopherol on airway macrophage function in healthy and mild allergic asthmatics by Geiser M1, Lay JC, Bennett WD, Zhou H, Wang X, Peden DB, Alexis NE.(PubMed)
(8) In vivo gamma-tocopherol supplementation decreases systemic oxidative stress and cytokine responses of human monocytes in normal and asthmatic subjects by Wiser J1, Alexis NE, Jiang Q, Wu W, Robinette C, Roubey R, Peden DB.(PubMed)
(9) Gamma-tocopherol prevents airway eosinophilia and mucous cell hyperplasia in experimentally induced allergic rhinitis and asthma by Wagner JG1, Jiang Q, Harkema JR, Ames BN, Illek B, Roubey RA, Peden DB.(PubMed)
(10) Oxidative stress and antioxidant status in Saudi asthmatic patients by Al-Afaleg NO1, Al-Senaidy A, El-Ansary A.(PubMed)
(11) Reduced circulating antioxidant defences are associated with airway hyper-responsiveness, poor control and severe disease pattern in asthma byWood LG1, Gibson PG.(PubMed)
(12) Natural-source d-α-tocopheryl acetate inhibits oxidant stress and modulates atopic asthma in humans in vivo by Hoskins A1, Roberts JL 2nd, Milne G, Choi L, Dworski R.(PubMed)

The smoothie of Whole Milk and Royal Jelly for Women who Want to get Pregnant

Kyle J. Norton(Scholar)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

The smoothie for infertile women

Yield: 2 serving (about 8 ounce each)
5 grams royal jelly
2 cup Homo milk



1. Place all ingredients in a blender and puree about 1 minute
2. Blend on high speed about 1 minute or until the mixture is thick and the ice is well crushed.
3. Serve immediately

The findings of a natural ingredient for treatment and delay the progression of Alzheimer's disease from scientific communities have not been abating. Many ingredients showed extremely prominent in animal studies do not produce the same effects in human trials.

Some renown institutions may have found the ingredients from natural sources, such as whole milk(2)and Royal Jelly(5)  for prevented risk and treatment of female infertility, recent studies suggested.

In women, high-fat dairy foods intake may decrease this risk of anovulatory infertility, according to the Harvard School of Public Health(2). In support of above, Dr. Chavarro JE and the reearch team said, "...., high fat dairy,.. related to lower ovulatory disorder infertility",in a cohort of 17,544 women without a history of infertility for 8 years(3).

The the World Health Organization in the study to improve fertility in women recommended daily intake of high-fat dairy is associate to improve women's fertility, along with fruit and vegetable products(4).

Monounsaturated fatty acids found abundantly in whole milk products, nuts and high fat fruits such as olives and avocados. Olive oil may also increase the chance of women fertility.dr. Szostak-Węgierek D. said," Adequate intake of monounsaturated fatty acids, derived mainly from vegetable fats, ...... may be effective in the prevention of infertility in females"(5).

Royal jelly, secreted by honey bee, fed bee larvae in the first few days and entire life of an adult queen with an aim of producing larvae for extension of the life of colony, induced the differentiation of honeybee larvae into queen may process the therapeutic values for treatment of female fertility(6), according to the University of Minnesota.
Royalactin, a phytochemical found in royal jelly, induced the differentiation of honeybee larvae into queens expressed the reproductive procedure through decreased developmental time, and increased the titre of juvenile hormone, an essential hormone for ovary development(7). 

According to the  Infertility Cure: The Ancient Chinese Wellness Program for Getting ... By Randine Lewis in comment of Royal Jelly for increased fertility said," Bogdan Tekavcic, a gynecologist, who found that women who were given bee pollen with royal jelly demonstrated improvement or disappearance of their menstrual problems compared to a placebo group who reported no difference"(8).

The combined whole milk and royal jelly may improve the chance of conceive of infertile women may contribute to further investigation of therapeutic natural ingredients for reduced risk and treatment of female infertility.

Women who are at increased risk of infertile due to family history, genetic mutation, aging,...... should drink at least one serving daily and women who can not get pregnant after 12 months of unprotected sexual intercourse should drink as much as they can, depending to digestive toleration.

Dietary pattern of phytoestrogens may be necessary to induce subtle hormonal changes. According to the Eunice Kennedy Shriver National Institute of Child Health and Human Development, serum of phytoestrogen is associate positively to short time for women to get pregnant(1). The study also suggested that couples who are attempting to conceive, should consider adding dietary rich of phytoestrogen fruits and vegetables into their diet(1).

Arthritis Is Curable
You Can Eliminate Osteoarthritis
By addressing the Underlying Causes through Clinical Trials and Studies

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to General health http://kylejnorton.blogspot.ca/

Super foods Library, Eat Yourself Healthy With The Best of the Best Nature Has to Offer

References

(1) Higher urinary lignan concentrations in women but not men are positively associated with shorter time to pregnancy by Mumford SL1, Sundaram R, Schisterman EF, Sweeney AM, Barr DB, Rybak ME, Maisog JM, Parker DL, Pfeiffer CM, Louis GM.(PubMed)
(2) A prospective study of dairy foods intake and anovulatory infertility by Chavarro JE1, Rich-Edwards JW, Rosner B, Willett WC.(PubMed)
(3) Diet and lifestyle in the prevention of ovulatory disorder infertility by Chavarro JE1, Rich-Edwards JW, Rosner BA, Willett WC.(PubMed)
(4) [The diet in improving fertility in women].[Article in Polish] by Sińska B, Kucharska A, Dmoch-Gajzlerska E.(PubMed)
(5) [Nutrition and fertility].[Article in Polish]by Szostak-Węgierek D1.(PubMed)
(6) Apiology: royal secrets in the queen's fat body by Yamanaka N1, O'Connor MB(PubMed)
(7) Royalactin induces queen differentiation in honeybees by Kamakura M1.(PubMed)
(8) The  Infertility Cure: The Ancient Chinese Wellness Program for Getting ... By Randine Lewis
(9) [Exploration into rules of combined Chinese and Western medical treatment on immune
infertility].[Article in Chinese] by Yao DN1, Chen WY, Xiao Y.(PubMed)
(10) [Hematopoietic effect of siwu decoction in the mice with blooddeficiency induced by compound method of bleeding, starved feeding and exhausting].[Article in Chinese] by Tan W1, Song CS, Tan HL, Liu LL, Ma ZC, Wang YG, Gao Y.(PubMed)

(11) Chemical fingerprinting and quantitative constituent analysis of Siwu decoction categorized formulae by UPLC-QTOF/MS/MS and HPLC-DAD by Shulan Su1, Wenxia Cui12, Wei Zhou1, Jin-ao Duan1*, Erxin Shang1 and Yuping Tang(Chinese medicine)

Most Common Diseases of elder: Respiratory Disease: Asthma Treatment In conventional medicine perspective

Kyle J. Norton(Scholar and Master of Nutrients, all right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

Respiratory Disease is defined as medical conditions which affect the breathing organ and tissues including Inflammatory lung disease, Obstructive lung diseases, Restrictive lung diseases, Respiratory tract infections, trachea, bronchi, bronchioles, alveoli, the nerves and muscles breathing , etc,.

                                         Asthma

 
Asthma is a chronic inflammatory disease affecting the air way of the lung with recurring symptoms, such as wheezing, chest tightness, shortness of breath, and coughing. The disease affects people of all ages, and mostly starts during childhood. In the study of 463,801 children aged 13-14 years in 155 collaborating centres in 56 countries. Children self-reported, through one-page questionnaires, symptoms of these three atopic disorders. In 99 centres in 42 countries, a video asthma questionnaire was also used for 304,796 children, found that for asthma symptoms, the highest 12-month prevalences were from centres in the UK, Australia, New Zealand, and Republic of Ireland, followed by most centres in North, Central, and South America; the lowest prevalences were from centres in several Eastern European countries, Indonesia, Greece, China, Taiwan, Uzbekistan, India, and Ethiopia(1). In the United States, approximately, asthma affects 25 million people, 7 million of them are children.

                                  The Treatment

In conventional medicine perspective
According to the guide line of Asthma society of Canada, Most people with asthma take two kinds of medication.
F.1.1. Controllers
Controllers are medication with an aim to prevent the inflammation of the airway. There are advised that patients aho are taking the cotrollers shoud continue to take them even without symptoms to prevent recurrence.
1. Corticosteroids
Corticosteroids are most frequent used controllers in preventing inflammatory airways in asthma patients.
a. Inhaled corticosteroids
According to the study by University of Nevada School of Medicine, in the review of review is to compare and contrast the newer inhaled corticosteroid (ICS) ciclesonide with older ICSs, showed that once-daily administration of ICSs is generally not as effective as twice-daily. Continuous administration of ICSs does not change the natural history of asthma in either children or adults. Long-term administration of medium dose ICSs does not increase the risk of cataracts or osteopenia in children and young adults(67). Others in the study of Dry powder inhaler (DPI) devices to assess the proportion of patients with asthma or chronic obstructive pulmonary disease (COPD) with significant bronchoobstruction who do not have inspiratory flows necessary for the adequate use of dry powder inhaler (DPI) devices Diskus and Turbuhaler. showed that significant proportion of patients with asthma or COPD with significant bronchoobstruction do not exhibit satisfactory inspiratory flows for the use of dry powder inhaler (DPI) devices (Diskus < Turbuhaler)(68).
b. Oral or intravenous corticosteroids
In the study of 47 patients, 30 females, 17 male, 24 received oral prednisolone and 23 received IV hydrocortisone. At baseline the oral and IV groups were similar (mean, SD) in age (38.3, 12.8 vs 37.3, 12.9, P=0.80) and initial percent predicted (PP) PEF (61, 16.7 vs 69, 13.0, P=0.11). After 72 h both groups had similar improvements in PEF (27%, 26 vs 27%, 19, P=0.96), researchers at the Department of Respiratory and Sleep Disorders Medicine, Western Hospital, found that Corticosteroids administered orally and IV had similar efficacy in the treatment of adults hospitalised with acute asthma(69).
c. Side effects
a.1. psychiatric side effects include mania, depression and mood disturbances within the first two weeks of corticosteroid therapy(70).
2. Short side effects include cutaneous effects, electrolyte abnormalities, hypertension, hyperglycemia, pancreatitis, hematologic, immunologic, and neuropsychologic effects. and Long-term corticosteroid use may be associated with more serious sequel, including osteoporosis, aseptic joint necrosis, adrenal insufficiency, gastrointestinal, hepatic, and ophthalmologic effects, hyperlipidemia, growth suppression, and possible congenital malformations(71).
2. Cromolyn sodium and nedocromil
a. The medication are used tr block part of the asthma immune response causes of airway inflammation.
Some researchers found that the asthma drugs cromolyn disodium and nedocromil sodium are potent G-protein-coupled receptor 35 (GPR35) agonists. In the study by Amgen San Francisco, South San Francisco, unlike zaprinast, a potent phosphodiesterase 5 (PDE5) inhibitor, cromolyn disodium and nedocromil sodium lack inhibitory activity towards PDE5. These findings suggest that GPR35 may play an important role in mast cell biology and be a potential target for the treatment of asthma(72).
b. Side effects are not limit to
Bad taste in mouth
Cough
Itching or sore throat
Headache
Sneezing or stuffy nose

3. Long-acting beta-2 agonists (LABAs)
a. The medication used with intention for long term control of the symptoms. Long-acting beta-agonist to an inhaled corticosteroid has been accepted as effective therapy for almost two decades, according to the study by Faculty of Medicine, Gazi University, Ankara, found that evidence supports the use of long-acting beta-2 agonists plus inhaled corticosteroids in a single inhaler device to increase adherence and reduce the potential use of long-acting beta-2 agonists monotherapy(73). Other indicated that in adolescents and adults with sub-optimal control on low dose ICS monotherapy, the combination of LABA and ICS is modestly more effective in reducing the risk of exacerbations requiring oral corticosteroids than a higher dose of ICS. Combination therapy also led to modestly greater improvement in lung function, symptoms and use of rescue ss(2) agonists and to fewer withdrawals due to poor asthma control than with a higher dose of inhaled corticosteroids(74).
b. Side effects are not limit to
LABAs may lead to a worsening of asthma symptoms, heart attack and even death, when used alone over a long period of time, (75).
4. Methylxanthines
a. The medication used to gether with inhaled Corticosteroids to prevent the nightmare symptoms of asthatic patients. The methylxanthine theophylline has demonstrated efficacy in attenuating the three cardinal features of asthma – reversible airflow obstruction, airway hyperresponsiveness, and airway inflammation, according to the study by University of North Carolina(76).
b. Side effects are not limit to Cardiac arrhythmias, CNS excitement, tremors, convulsions, and GI irritation.
5. Leukotriene modifiers including cysteinyl LTs (CysLTs) and LTB(4)
a. The medication may be used as alternative for patient with low dose inhaled corticosteroids. Acording to the study by Catholic University of the Sacred Heart, Rome,, LTB(4) might have a role in severe asthma, asthma exacerbations, and the development of airway hyperresponsiveness. CysLT(1) receptor antagonists can be given orally as monotherapy in patients with mild persistent asthma, but these drugs are generally less effective than inhaled glucocorticoids. Combination of CysLT(1) receptor antagonists and inhaled glucocorticoids in patients with more severe asthma may improve asthma control and enable the dose of inhaled glucocorticoids to be reduced while maintaining similar efficacy(77).
b. Side effects are not limit to headache, stomachache or flu-like.
6. Etc.
F.1.2. Relievers
The aim of the medication are to to alleviate symptoms immediately.
1. Short-acting beta-2 agonists
a. Some researchers indicated that although Inhaled beta-adrenergic agonist bronchodilators are integral components of effective asthma treatment, but long-term use of both long-acting and short-acting inhaled beta-agonists may cause a loss of asthma control in some patients(78). But other found evidence against concerns over regular use of inhaled short-acting beta-2 agonists(79).
b. Side effects are not limit to headache and dizziness. Nausea, Vmiting, Diarhea, Anixety, Nervousness or tremor
2. Anticholinergics
In the study of data from 32 randomised controlled trials (n = 3611 subjects) showed significant reductions in hospital admissions in both children (RR = 0.73; 95% CI 0.63 to 0.85, p = 0.0001) and adults (RR = 0.68; 95% CI 0.53 to 0.86, p = 0.002) treated with inhaled anticholinergic agents, combined treatment also produced a significant increase in spirometric parameters 60-120 minutes after the last treatment in both children (SMD = -0.54; 95% CI -0.28 to -0.81, p = 0.0001) and adults (SMD = -0.36; 95% CI -0.23 to -0.49, p = 0.00001), conducted by Departamento de Emergencia, Hospital Central de las FF.AA, suggested that the addition of multiple doses of inhaled ipratropium bromide to beta(2) agonists is indicated as the standard treatment in children, adolescents, and adults with moderate to severe exacerbations of asthma in the emergency setting(80).

Arthritis Is Curable
You Can Eliminate Osteoarthritis
By addressing the Underlying Causes through Clinical Trials and Studies

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Super foods Library, Eat Yourself Healthy With The Best of the Best Nature Has to Offer recommended by Kyle J. Norton

Back to Kyle J. Norton Home page http://kylejnorton.blogspot.ca
Sources
(1) http://www.ncbi.nlm.nih.gov/pubmed/9643741
(66) http://www.ncbi.nlm.nih.gov/pubmed/22592572
(67) http://www.ncbi.nlm.nih.gov/pubmed/21720220
(68) http://www.ncbi.nlm.nih.gov/pubmed/22768682
(69) http://www.ncbi.nlm.nih.gov/pubmed/15707855
(70) http://www.ncbi.nlm.nih.gov/pubmed/10619339
(71) http://www.ncbi.nlm.nih.gov/pubmed/11588541
(72) http://www.ncbi.nlm.nih.gov/pubmed/20559017
(73) http://www.ncbi.nlm.nih.gov/pubmed/22233316
(74) http://www.ncbi.nlm.nih.gov/pubmed/20393943
(75) http://www.defectivedrug.com/drugs/labas/
(76) http://www.ncbi.nlm.nih.gov/pubmed/20859807
(77) http://www.ncbi.nlm.nih.gov/pubmed/21059119
(78) http://www.ncbi.nlm.nih.gov/pubmed/8687259
(79) http://www.ncbi.nlm.nih.gov/pubmed/12804401
(80) http://www.ncbi.nlm.nih.gov/pubmed/16055613

The Curable Smoothie of Ginger, Pineapple and Orange for Reduced Risk and Treatment of Lower Back Pain Back by Clinical trials and Studies of Respectable Institutions

Kyle J. Norton(Scholar, Master of Nutrients)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

The smoothie for reduced risk and treatment of Lower Back Pain

Yield: 2 serving (about 8 ounce each)
3/4 cup pineapple
3/4 cup orange
1 cup herbal ginger tea drink (Make from 4 grams(2 tea bags) of green tea, and a cup of hot water lipped for 5 minutes, and set aside for cooling to room temperature)


1. Place the grapes, green tea, in a blender and puree about 1 minute
2. Blend on high speed about 1 minute or until the mixture is thick and the ice is well crushed.
3. Serve immediately

The findings of a natural ingredient for treatment  of Lower Back Pain from scientific communities have not been abating. Many ingredients showed extremely prominent in animal studies do not produce the same effects in human trials.

According to the recent studies by the well known institutions, ginger(1), Pineapple(5) and orange(10), may hold a key for potential and therapeutic values for attenuated symptoms and treatment of lower back pain.

Ginger (Zingiber officinale) or ginger root is the genus Zingiber, belonging to the family Zingiberaceae, native to Tamil. It has been used in traditional and Chinese medicine to treat dyspepsia, gastroparesis, constipation, edema, difficult urination, colic, etc.

Strong evidence in pidemiological studies linking ginger phytochemicals in reduced symptoms of pain and treatment of chronic pain diseases may be due to its hypoalgesic and anti inflammatory activities(1)(4).

A 164 patients screened, 140 eligible, 70 were randomized to the application of aromatic ginger oil (SMGO) on chronic low back pain study, exhibited a significant improvements in pain intensity and disability (p<0.05) across the period of assessments in immediate, short- and long-term effectiveness(2).

According to the University of Freiburg im Breisgau, ginger has shown a moderate effect as a herbal medicine in the treatment of osteoarthritic complaints and chronic low back pain but further studies are necessary to enable acceptance of the herbal medicines into the treatment guidelines(3).

Intake of melatonin enhancer fruits, such as pineapple and orange can improve sleep quality, pain and pain threshold, particular on pain score on the Visual Analog Scale, according to the study by the Universidade Federal do Rio Grande do Sul (UFRGS)(5).

In chronic lower back pain patient, Dr. Kurganova YM and Dr. Danilov AB. said, in application over 12 weeks of melatonin in patient with lower back pain " (there is) a significant reduction in pain intensity at movement and resting state.....in the main groups compared to controls" and " ossible mechanisms of analgesic properties of melatonin and world experience in chronic low back pain treatment"(6). Other study suggested that the effectiveness of melatonin in pain relief in chronic pain patient, probably due to its analgesic possibilities(7).

According to the Ubon Ratchathani University, intake of pineapple and orange in health subjects experiment showed to increase the serum melatonin concentrations as well as raising the antioxidant capacity in proportion to serum melatonin levels(8). 

Pineapple is a species of Ananas Comos. belongings to the family Bromeliaceae and native to southern Brazil and Paraguay. Today it is widely cultivated for commercial and its rich of vitamins and mineral and digesting enzyme bromelin which seems to help digestion at the end of a high protein meal. It is second only to banana as America's most favourite tropical fruit

Dr. Johns NP and colleagues at the Khon Kaen University said," selected fruits(pineapple, orange and banana) consumption may reduce age-related melatonin reduction problems such as sleeplessness and illnesses involving oxidative damage"(9).

Orange is a species of Citrus Sinensis, belong to the family Rutaceae and native to the Southeast Asia. Orange is round citrus fruits with finely-textured skins, orange in color and one of most popular fruits in the world.

The increased levels of melatonin content during alcoholic fermentation of orange juice may hold a key to attenuate the melatonin due to ageing(10).

Dr. Huang X and Dr. Mazza G. said," orange had the highest melatonin content" in the the direct analysis of initial methanol extracts was compared with further ethyl acetate extraction(11).

Taking altogether, intake of combination of ginger, pineapple and orange  induced the production of melatonin in improved the sleep pattern and reduced significantly pain on pain score may be beneficiary for treatment of symptoms of  lower back pain

People who are at higher risk of lower back pain due to aging or occupations,...may drink one or 2 servings a day, people with lower back pain should drink as much as they can depending to the digestive alternation.

All Forms of Arthritis are Curable
You Can Eliminate Osteoarthritis
By addressing the Underlying Causes through Clinical Trials and Studies

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

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References

(1) Ginger (Zingiber officinale) reduces muscle pain caused by eccentric exercise by Black CD1, Herring MP, Hurley DJ, O'Connor PJ.(PubMed)

(2) The effectiveness of Swedish massage with aromatic ginger oil in treating chronic low back pain in older adults: a randomized controlled trial by Sritoomma N1, Moyle W2, Cooke M3, O'Dwyer S4.(PubMed)

(3) Evidence of effectiveness of herbal antiinflammatory drugs in the treatment of painful osteoarthritis and chroniclow back pain by Chrubasik JE1, Roufogalis BD, Chrubasik S.(PubMed)

(4) Acute effects of dietary ginger on muscle pain induced by eccentric exercise by Black CD1, O'Connor PJ.(PubMed)
(5) Melatonin analgesia is associated with improvement of the descending endogenous pain-modulating system infibromyalgia: a phase II, randomized, double-dummy, controlled trial BY de Zanette SA, Vercelino R, Laste G, Rozisky JR, Schwertner A, Machado CB, Xavier F, de Souza IC, Deitos A, Torres IL, Caumo W1.(PubMed)
(6) [A role of melatonin in the treatment of low back pain].[Article in Russian] by Kurganova YM, Danilov AB(PubMed)
(7) [Melatonin and pain].[Article in Russian] by Kurganova IuM, Danilov AB, Goriachev DV.(PubMed)
(8) Serum melatonin levels and antioxidant capacities after consumption of pineapple, orange, or banana by healthy male volunteers by Sae-Teaw M1, Johns J, Johns NP, Subongkot S.(PubMed)
(9) Dietary intake of melatonin from tropical fruit altered urinary excretion of 6-sulfatoxymelatonin in healthy volunteers by Johns NP1, Johns J, Porasuphatana S, Plaimee P, Sae-Teaw M.(PubMed)
(10) Alcoholic fermentation induces melatonin synthesis in orange juice by Fernández-Pachón MS1, Medina S, Herrero-Martín G, Cerrillo I, Berná G, Escudero-López B, Ferreres F, Martín F, García-Parrilla MC, Gil-Izquierdo A.(PubMed)
(11) Simultaneous analysis of serotonin, melatonin, piceid and resveratrol in fruits using liquid chromatography tandem mass spectrometry by Huang X1, Mazza G.(PubMed)

Most Common Diseases of elder: Respiratory Disease: Asthma Treatment: The Important Folate

Kyle J. Norton(Scholar and Master of Nutrients)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

Respiratory Disease is defined as medical conditions which affect the breathing organ and tissues including Inflammatory lung disease, Obstructive lung diseases, Restrictive lung diseases, Respiratory tract infections, trachea, bronchi, bronchioles, alveoli, the nerves and muscles breathing , etc,.

                                  Asthma

Asthma is a chronic inflammatory disease affecting the air way of the lung with recurring symptoms, such as wheezing, chest tightness, shortness of breath, and coughing. The disease affects people of all ages, and mostly starts during childhood. In the study of 463,801 children aged 13-14 years in 155 collaborating centres in 56 countries. Children self-reported, through one-page questionnaires, symptoms of these three atopic disorders. In 99 centres in 42 countries, a video asthma questionnaire was also used for 304,796 children, found that for asthma symptoms, the highest 12-month prevalences were from centres in the UK, Australia, New Zealand, and Republic of Ireland, followed by most centres in North, Central, and South America; the lowest prevalences were from centres in several Eastern European countries, Indonesia, Greece, China, Taiwan, Uzbekistan, India, and Ethiopia(1). In the United States, approximately, asthma affects 25 million people, 7 million of them are children.

                   The Effectiveness of Folate

Folate, also known as folic acid, vitamin B9, is a water soluble vitamin, found abundantly in leafy vegetables, citrus fruits, beans, whole grain, etc. The vitamin plays an important role in synthesize DNA, repair DNA, and methylate DNA as well as to act as a cofactor in certain biological reactions, production of red blood cells for anemia prevention.

1. Serum levels of folate
Scientific studies, serum levels of folate may associate to risk of asthma. The study by Ain Shams University showed that serum folate levels are significantly lower among atopics, and correlate inversely with the degree of atopy among asthmatics(1). Other researchers suggested that low serum folate and impaired folate metabolism may be a potential risk factors for development of asthma and atopic disease. According to The Capital Region of Denmark, in a random sample of 6784 persons from a general population aged 30-60 years participated in a health examination in 1999-2001, low levels of serum of folate were associated with self-reported doctor-diagnosedasthma and attacks of shortness of breath, but not with lung function or atopy(2). The Johns Hopkins School of Medicine study also indicated that the effects of serum levels of folate were associated inversely associated with high total IgE levels, atopy, and wheeze(3).

2. The effects of folate in maternal intake
Folic acid supplementation has an established role in early pregnancy for preventing neural tube defects, but its causes of childhood asthma and asthmatic symptoms in epidemiological studies have been inconclusive. According to the University of Western Australia, maternal folic acid exposure may be associated to childhood asthma and wheeze(4). Other in the study of pre-natal FACSs exposure population showed a small increased risk of early wheeze, but no adverse association of respiratory or allergic outcomes(5). In the study using the data from an Australian prospective birth cohort study (n = 557) from 1998 to 2005. At 3.5 years and 5.5 years, 490 and 423 mothers and children participation, researchers at the The University of Adelaide, indicated the correlation of the supplementation with folate in pregnancy and incidence of childhood allergic asthma through epigenetic mechanisms and also associated with poorer respiratory outcomes in young children(6).

Since the search of the effect of folate intake in reduced risk and treatment of asthma have produced limitation of result, we concluded that folate deficiency or low levels of folate may be associated to increased risk of early onset of the disease, but multi centers and large sample size studies are necessary to improve its validation. Overdoses of folate may cause stomach problems, sleep problems, skin reactions, seizures, etc., please make sure you follow the guideline of the Institute of Medicine of the National Academies.


All Forms of Arthritis are Curable
You Can Eliminate Osteoarthritis
By addressing the Underlying Causes through Clinical Trials and Studies

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Super foods Library, Eat Yourself Healthy With The Best of the Best Nature Has to Offer recommended by Kyle J. Norton

Back to Kyle J. Norton Home page http://kylejnorton.blogspot.ca

References
(1) Study of folate status among Egyptian asthmatics by Farres MN1, Shahin RY, Melek NA, El-Kabarity RH, Arafa NA.(PubMed)
(2) Atopy, asthma, and lung function in relation to folate and vitamin B(12) in adults by Thuesen BH1, Husemoen LL, Ovesen L, Jørgensen T, Fenger M, Gilderson G, Linneberg A.(PubMed)
(3) Higher serum folate levels are associated with a lower risk of atopy and wheeze by Matsui EC1, Matsui W.(PubMed)
(4) Folic acid in pregnancy - is there a link with childhood asthma or wheeze? by Sharland E1, Montgomery B, Granell R.(PubMed)
(5) Maternal use of folic acid supplements during pregnancy, and childhood respiratory health and atopy by Bekkers MB1, Elstgeest LE, Scholtens S, Haveman-Nies A, de Jongste JC, Kerkhof M, Koppelman GH, Gehring U, Smit HA, Wijga AH.(PubMed)
(6) Effect of supplemental folic acid in pregnancy on childhood asthma: a prospective birth cohort study by Whitrow MJ1, Moore VM, Rumbold AR, Davies MJ.(PubMed)

The Tasty Green tea, Grape and Asparagus for reduced risk and treatment of Gout

Kyle J. Norton(Scholar, Master of Nutrients), all right reserved.
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.


The smoothie for reduced risk and Treatment of Gout
Yield: 2 serving (about 8 ounce each)
1 1/4 cups grape

1/4 cup asparagus
1 cup green tea drink (Make from 4 grams of green tea, and a cup of hot water lipped for 5 minutes. Set aside for cooling to room temperature)

1. Place all ingredients in a blender and puree about 1 minute
2. Blend on high speed about 1 minute or until the mixture is thick and the ice is well crushed. Add more green tea drink if needed
3. Serve immediately

The finding the natural ingredients for treatment of Gout is considered as a dream of many scientist to replace the long usage adverse effect of conventional medicine to other organs in the body.
Unfortunately, many compounds found effective in initial studying failed to confirm the potential in large sample size and multi center.

Recent studies suggested that scientist in some research centers have found the naturally potential ingredients, such as green tea(1), Grape(4) and Asparagus(7) for reduced risk and treatment for gout.

Gout mostly effected one joint is defined as a acute and recurrent condition of arthritis as a result of uric acid builds up in blood cause of joint inflammation.

Green tea has been a precious drink in traditional Chinese culture and used exceptional in socialization for more than 4000 thousand years.Green tea glycosides, including quercetin and rutin applied to orally to the oxonate-induced hyperuricemic mice 3 time a day, exhibited the anti xanthine dehydrogenase/xanthine oxidase (XDH/XO), the cofactors to produce uric acid activities(1).

According to the Chiang Mai University, green tea extract (GTE) also promoted hypouricemic and anti gout effects through modestly lowering serum uric acid (SUA) level and decreasing uric acid clearance(2).

A randomly stratified cluster sampling conducted with 7403 inhabitants aged over 20 years in Foshan areas, suggested that intake of green tea is found to associated to reduced risk of gout. Reduced intake of food with rich purine, alcohol intake as well as controlling obesity and blood pressure, improving the status of lipid metabolic disorder together with programs as hypertension control etc.(3).

Grape is a woody vines of the genus Vitis, belong to the family Vitaceae, native to southern Turkey. Its phytochemical resveratrol (RSV) has found to reduce risk and treatment of gout in traditional medicine(4).

According to the Osaka University, resveratrol (RSV) also inhibits NLRP3-inflammasome (inflammatory cytokines)activation and mediate the immune responses causes inflammatory diseases, including gout(5).

Dr. Wang Y and colleagues at the Nanjing University said,"procyanidins from grape seeds possess in vivo urate-lowering activities"(6).

Asparagus is a flowering plant belongings to species the genus Asparagus, native to the western coasts of northern Spain, north to Ireland, Great Britain, and northwest Germany, northern Africa and western Asia. Asparagus has been used from early times as a vegetable and medicine, because of its delicate flavour and diuretic properties.

Crude saponin extracts from asparagus used in the treatment of rheumatoid arthritis, gout and haemorrhoids in Nigerian medicinal plants, probably doe to their anti inflammatory diseases activities(8).

According to Dr. Nile SH and vDr. Park SW, The total phenolic and flavonoid from asparagus extract exhibited significant xanthine oxidase inhibitory activity in related to production of uric acids in inducing the risk of gout(7).

These finding of the effectiveness of Green Tea, Grape and Asparagus  may serve as cornerstones of pharmaceutical target for further studies as well as a potential medication for treatment of Gout without adverse effects.

People who are at high risk of gout such as family history,.....should drink at least one cup daily and people with gout should drink the juices as much as they can, depending to digestive toleration.

Change of life style and diet pattern are also recommended.

All Forms of Arthritis are Curable
You Can Eliminate Osteoarthritis
By addressing the Underlying Causes through Clinical Trials and Studies

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Super foods Library, Eat Yourself Healthy With The Best of the Best Nature Has to Offerrecommended by Kyle J. Norton

Back to Kyle J. Norton Home page http://kylejnorton.blogspot.ca

References

(1) Effects of Biota orientalis extract and its flavonoid constituents, quercetin and rutin on serum uric acid levels in oxonate-induced mice and xanthine dehydrogenase and xanthine oxidase activities in mouse liver by Zhu JX1, Wang Y, Kong LD, Yang C, Zhang X.(PubMed)

(2) Effects of green tea extract on serum uric acid and urate clearance in healthy individuals by Jatuworapruk K1, Srichairatanakool S, Ounjaijean S, Kasitanon N, Wangkaew S, Louthrenoo W.(PubMed)

(3) [Epidemiological study on hyperuricemia and gout in Foshan areas, Guangdong province.][Article in Chinese] by Yu JW1, Yang TG, Diao WX, Cai XQ, Li T, Zhong H, Hu DL, Chen CQ, Chen ZX.(PubMed)
(4) Effects of resveratrol on collagen type II protein in the superficial and middle zone chondrocytes of porcine articular cartilage by Maepa M1, Razwinani M1, Motaung S1.(PubMed)
(5) Resveratrol inhibits the acetylated α-tubulin-mediated assembly of the NLRP3-inflammasome. by Misawa T1, Saitoh T1, Kozaki T1, Park S1, Takahama M1, Akira S1.(PubMed)
(6) Administration of procyanidins from grape seeds reduces serum uric acid levels and decreases hepatic xanthine dehydrogenase/oxidase activities in oxonate-treated mice by Wang Y1, Zhu JX, Kong LD, Yang C, Cheng CH, Zhang X.(PubMed)
(7) HPTLC Analysis, Antioxidant and Antigout Activity of Indian Plants by Nile SH1, Park SW1.(PubMed)