The Smoothie of Broccoli, Peanut, Sweet Potato and Low fat Milk for Prevention and Treatment of Intrahepatic cholestasis of pregnancy

Kyle J. Norton(Scholar, Master of Nutrients), all right reserved.
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

The smoothie for prevention and treatment of intrahepatic cholestasis of pregnancy
Yield: 2 servings (about 8 ounces each)
1/2 cup broccoli
1/2 cup peanut
1/2 cup sweet potato
1 cup green tea drink (Make from 4 grams(2 tea bags) of green tea, a slice of ginger and a cup of hot water lipped for 5 minutes, and set aside for cooling to room temperature).

1. Place all ingredients in a blender and puree about 1 minute
2. Blend on high speed about 1 minute or until the mixture is thick and the ice is well crushed.
3. Serve immediately

The finding of a natural source for treatment of intrahepatic cholestasis of pregnancy has been running into many obstacles, many ingredients showed initially with promising result in animal studies have not produced same potentials in large sample size and mutli centers human trials.

Intrahepatic cholestasis of pregnancy is a medical condition during pregnancy in which bile cannot flow from the liver to the duodenum. According to the Sichuan University, increased oxidative stress due to lipid peroxidation and inflammatory activity(2) in prevention of natural antioxidant to perform its tast effectively(1).

Recent studies back by well known institutions proposed, CoQ, Vitamin E, D and and K nut may be the next generation of natural ingredients for prevention and treatment of intrahepatic cholestasis of pregnancy

Coenzyme Q and vitamin E found abundantly in peanut and sweet potato respectively, may be used for prevention and treatment of intrahepatic cholestasis of pregnancy, according to the Universidad de Buenos Aires(3).

In the investigation of the effect of vitamin D, found abundantly in low fat milk in women with intrahepatic cholestasis of pregnancy, Dr. Wikström Shemer E and Dr. Marschall HU. suggested, low levels of vitamin D not only indicate fetal distress but also reduce vitamin D function in regulated steroid metabolism(4). 

Other study proposed the well-timed Vitamin K, (found in high amount in bbroccoli) therapy in all cases with impaired secretion of bile during pregnancy may necessary for women with intrahepatic cholestasis of pregnancy(5).

The effectiveness of Broccoli, Peanut, Sweet Potato and Low fat Milk may serve as cornerstones of pharmaceutical target for further studies in production of a potential medication for prevention and  treatment of intrahepatic cholestasis of pregnancy with little or no adverse effects.

People who are at high risk of intrahepatic cholestasis of pregnancy due to family history, weaken immune system,..... should drink at least one serving daily and people with intrahepatic cholestasis of pregnancy should drink the smoothie as much as they can, depending to digestive toleration.
Life style and dietary patter change are recommended.

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You Can Eliminate Osteoarthritis

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Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

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(1) Oxidative stress markers in intrahepatic cholestasis of pregnancy: a prospective controlled study. by Hu YY1, Liu JC, Xing AY.(PubMed) 

(2) Placental ADAMTS-12 Levels in the Pathogenesis of Preeclampsia and Intrahepatic Cholestasis of Pregnancy. by Oztas E1, Ozler S2, Ersoy AO2, Erkenekli K2, Sucak A2, Ergin M3, Uygur D2, Danisman N2.(PubMed)
(3) Coenzyme Q in pregnant women and rats with intrahepatic cholestasis by Martinefski MR1, Contin MD, Rodriguez MR, Geréz EM, Galleano ML, Lucangioli SE, Bianciotti LG, Tripodi VP.(PubMed)
(4) Decreased 1,25-dihydroxy vitamin D levels in women with intrahepatic cholestasis of pregnancy by Wikström Shemer E1, Marschall HU.(PubMed)

The smoothie Green Tea, Turmeric and Grape for reduced risk and treatment of Hodgkin's Lymphoma Back By Clinical Trials and Studies

Kyle J. Norton(Scholar, Master of Nutrients) All right reserved.
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.


The smoothie for reduced risk and treatment of Hodgkin's Lymphoma
Yield: 2 serving (about 8 ounce each)
1 1/2 cups grape
1/2 tsp curcumin
1 cup green tea drink (Make from 4 grams of green tea, a cup of hot water lipped for 5 minutes, and set aside for cooling to room temperature)


1. Place all ingredients in a blender and puree about 1 minute
2. Blend on high speed about 1 minute or until the mixture is thick and the ice is well crushed. Add more green tea drink if needed
3. Serve immediately

The identification of the natural ingredients for treatment of Hodgkin's Lymphoma  is considered as a dream of many scientist to replace the long usage adverse effect of conventional medicine to other organs in the body. Unfortunately, many compounds found effective in initial studying failed to confirm the potential in large sample size and multi center.

Recent studies back by well known institution suggested that the naturally potential ingredients green tea, Grape and Asparagus may be effective for reduced risk and treatment for Hodgkin's Lymphoma,

Hodgkin's Lymphoma, a type of lymphoma is also known as Hodgkin's Disease started from the lymph nodes in the chest, armpits and neck. It was named under Thomas Hodgkin, for first to describe the abnormalities of the lymph system in 1832. Hodgkin's lyphoma, is invasive and tends to spread orderly from one lymph node group to another. It is not a common disease with approximately 800 and 7000 of new cases reported every year in Canada and US accordingly and mostly occurs to young adults and after the age of 45.

Resveratrol is a phytochemical in the class of Stilbenoids, found abundantly in skins and seed of grape and red wine may be a potential ingredient for risk reduction and treatment of Hodgkin's Lymphoma, through inhibited the metabolic activation of carcinogens, upregulated antioxidant and anti-inflammatory properties, decreased cell proliferation and induced apoptosis(1).

Dr. Frazzi R and colleagues at the Oncology Department, IRCCS - Arcispedale S. Maria Nuova, Reggio Emilia, Italy, the phytochemical also induced cell death in Hodgkin lymphoma (HL)-derived L-428 cells in a dose-dependent manner, through upregulating anti body and down regulating the inflammatory pathways(2).

Green tea has been a precious drink in traditional Chinese culture and used exceptional in socialization for more than 4000 thousand years. Because of their health benefits, they have been cultivated for commercial purposes all over the world. its phytochemical, Epigallocatechin-3-gallate (EGCG), a phytochemicals found abundantly in green tea has enhanced the protective effects against Lymphoma(3).

Dr. Renno WM and research team at the Kuwait University, also suggested, (-)-epigallocatechin-3-gallate (EGCG) inhibited Hodgkin's Lymphoma through reduced the expression of gene of glial fibrillary acidic protein of CNS and increased the expression of growth-associated protein 43, a marker of regenerating axons(4).

Saponin and phenolic compounds from green tea expressed immunomodulatory effect of tea saponin against Hodgkin lymphoma (HL) through regulation of cytokine response and mitogen-activated protein kinases (MAPK) signaling inflammatory pathway(5).

Turmeric, a principal curcuminoid of the popular Indian spice, a rhizomatousherbaceous perennial plant of the ginger family, Zingiberaceae, native to tropical South Asia. Its chemical compound, curcumin, also process the potential effect against Hodgkin's Lymphoma through expression of down regulation of various inflammatory cytokine and related pathways(6).

Dr. Qiao Q and colleagues at the he First Hospital of China Medical University also said, curcumin inhibited constitutive and radiation-induced expression of the (Cell cycle) PI3K/AKT pathway and its downstream regulator nuclear factor kappaB (NF-κB)(Pro inflammatory pathways) in human Burkitt's lymphoma, a high-grade non-Hodgkin's lymphoma (NHL)(7)and gene expression of STAT3 in Chronic lymphocytic leukemia B cells in regulating the pro inflammatory pathways(8).

The identification of ingredient of Green Tea, Turmeric and Grape may serve as a foundation for establish a potential and natural source for reduced early onset and treatment of Hodgkin's Lymphoma in sometime in the future.

People who are at increased risk of Hodgkin's Lymphoma due to family history and aging should drink at least 2 servings a day and people with Hodgkin's Lymphoma should drink as much as they can, depending to the digestive toleration. Change of life style and dietary pattern are recommended.

All Forms of Arthritis are Curable
You Can Eliminate Osteoarthritis
By addressing the Underlying Causes through Clinical Trials and Studies

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to General health http://kylejnorton.blogspot.ca/p/general-health.html

Back to Kyle J. Norton Home page http://kylejnorton.blogspot.ca

References

(1) Wine and resveratrol: mechanisms of cancer prevention? by Bianchini F1, Vainio H.(PubMed)

(2) Resveratrol-mediated apoptosis of hodgkin lymphoma cells involves SIRT1 inhibition and FOXO3a hyperacetylation by Frazzi R1, Valli R, Tamagnini I, Casali B, Latruffe N, Merli F.(PubMed)

(3) [Demethylation and transcription of p16 gene in malignant lymphoma cell line CA46 induced by EGCG].[Article in Chinese] by Yu AF1, Shen JZ, Chen ZZ, Fan LP, Lin FA.(PubMed)

(4) (-)-Epigallocatechin-3-gallate modulates spinal cord neuronal degeneration by enhancing growth-associated protein 43, B-cell lymphoma 2, and decreasing B-cell lymphoma 2-associated x protein expression after sciatic nerve crush injury by Renno WM1, Al-Maghrebi M, Rao MS, Khraishah H.(PubMed)

(5) Immunomodulatory effect of tea saponin in immune T-cells and T-lymphoma cells via regulation of Th1, Th2 immune response and MAPK/ERK2 signaling pathway by Bhardwaj J1, Chaudhary N, Seo HJ, Kim MY, Shin TS, Kim JD.(PubMed)

(6) Curcumin induces cell-arrest and apoptosis in association with the inhibition of constitutively active NF-kappaB and STAT3 pathways in Hodgkin's lymphoma cells by Mackenzie GG1, Queisser N, Wolfson ML, Fraga CG, Adamo AM, Oteiza PI.(PubMed)

(7) Inhibition of the PI3K/AKT-NF-κB pathway with curcumin enhanced radiation-induced apoptosis in human Burkitt's lymphoma by Qiao Q1, Jiang Y, Li G.(PubMed)

(8) Curcumin induces cell-arrest and apoptosis in association with the inhibition of constitutively active NF-kappaB and STAT3 pathways in Hodgkin's lymphoma cells by Mackenzie GG1, Queisser N, Wolfson ML, Fraga CG, Adamo AM, Oteiza PI.(PubMed)

Most Common Diseases of elder: Upper respiratory tract infection(Respiratory Disease) – The do and do not’s list

Kyle J. Norton(Scholar and Master of Nutrients, all right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

                            Respiratory Disease 

Respiratory Disease is defined as medical conditions, affecting the breathing organ and tissues including Inflammatory lung disease, Obstructive lung diseases, Restrictive lung diseases, Respiratory tract infections, trachea, bronchi, bronchioles, alveoli, the nerves and muscles breathing , etc,.

                     Upper respiratory tract infection

Upper respiratory tract infections are considered to be the infection of the airway above the glottis or vocal cords. This includes the nose, sinuses, pharynx, and larynx, including the infection of tonsillitis, pharyngitis, laryngitis, sinusitis, etc,.

Prevention: The do and do not’s list

1. Wash your hand thoroughly with soap and water 15-20 seconds can help to reduce the risk of catching common cold and influenza. Use alcohol-based hand gels if washing is not possible.
2. Cover sneeze and coughing and prevent hand-to-hand passage.
3. Enhance your immune function to protect your body against invasion of foreign invasion, including bacteria and virus.
4. Traditional Mediterranean diet
Eating plenty of fruit, vegetables and fish keep lungs healthy. Those who follow a diet closest to this ” Mediterranean ” ideal are less likely as their peers with eating habits furthest from this pattern to develop chronic lung disease. A good amount of fresh vegetable juices are a good way to start healing, along with adding a variety of spices such as ginger, onions, and garlic. The emphasis should be on eating as healthy a diet as possible(22).
5. Eat your fruit and vegetables
Fruits and vegetables not only are very nutritional but also contains high amount of antioxidants which can combat against bacteria and virus invasion.
6. Etc.

All Forms of Arthritis are Curable
You Can Eliminate Osteoarthritis
By addressing the Underlying Causes through Clinical Trials and Studies

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to General health http://kylejnorton.blogspot.ca/p/general-health.html

Back to Kyle J. Norton Home page http://kylejnorton.blogspot.ca

Sources
(22) http://www.raysahelian.com/lungdisease.htm

The smoothie Green Tea, Tomato and Grape for reduced risk and treatment of Dementia Back By Clinical Trials and Studies

Kyle J. Norton(Scholar, Master of Nutrients) All right reserved.
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.


The smoothie for reduced risk and treatment of dementia
Yield: 2 serving (about 8 ounce each)
1 1/4 cups blueberry
1/4 cup acocado
1 cup green tea drink (Make from 4 grams of green tea, a slice of ginger and a cup of hot water lipped for 5 minutes, and let cool to room temperature)


1. Place all ingredients in a blender and puree about 1 minute
2. Blend on high speed about 1 minute or until the mixture is thick and the ice is well crushed. Add more green tea drink if needed
3. Serve immediately

The finding of a natural source for reduced risk and treatment of dementia has encountered many obstacles, many ingredients showed initially promising result in animal studies have not produced same potentials in either large sample size and mutli centers human trials.

Recent studies by some well known institutions suggested that green tea(1), tomato(5) and green tea(8) may process phytochemicals and ingredients effectively in reduced risk and treatment of dementia.

Green tea has been a precious drink in traditional Chinese culture and used exceptional in socialization for more than 4000 thousand years. Because of their health benefits, they have been cultivated for commercial purposes all over the world. According to the Universidade Federal do Rio Grande do Sul, green tea (-)epigallocatechin-3-gallate inhibited dementia through reversed oxidative stress and reduced acetylcholinesterase activity(1) and ameliorated learning and memory deficits in diabetic rats(2).

Dr. Panza F and the colleagues at the joint study lead by the University of Bari Aldo Moro, insisted green tea consumption prevented or postponed the onset of AD and delayed or slowed the progression dementia(3).

Furthermore, green tea inhibited Aβ-induced paralysis through its aroma fraction and antioxidant effects, according to the Saitama Cancer Center , Saitama , Japan(4).

Tomato is a red, edible fruit, genus Solanum, belongs to family Solanaceae, native to South America. Because of its health benefits, tomato is grown world wide for commercial purpose
and often in green house. Recent study showed that patients with dementia are associated to low levels of plasma Carotenoids(5), the major chemical constituent found in tomato.

Lycopene, another major phytochemical found in tomato inhibited the early onset of dementia through its effect in modulation of nitric oxide against 3-NP-induced behavioral, biochemical and cellular alterations in rats(6). Dr. Kumar P and Dr. Kumar A.in study of the effects of lycopene and epigallocatechin-3-gallate gainst 3-Nitropropionic acid, a neurotoxin induced gait and memory impairment in test animals, suggested, lycopene and EGCG could be used to mange 3-NP induced behavioral and biochemical alterations through nitric oxide pathways(7).

Resveratrol, a phytochemical in the class of Stilbenoids, found abundantly in grape also inhibited symptoms of vascular dementia in postmenopausal elderly women, depending to chronic use manner(8). Dr. Hu J and colleagues at the Xiamen University, also found that resveratrol expressed its β-secretase inhibitor effect through inhibited β-secretase activity and β-amyloid generation in animal model(9).

Furthermore, the phytochemical also exerted its neuroprotective effects, through ameliorate the harmful effect against the expression of pro inflammatory cytokine pathways(10).

The identification of ingredient of Green Tea, Tomato and Grape may serve as a foundation for establish a potential and natural source for reduced early onset and treatment of dementia in sometime in the future.

People who are at increased risk of dementia due to family history and aging should drink at least 2 servings a day and people with dementia should drink as much as they can, depending to the digestive toleration. Change of life style and dietary pattern are recommended.

All Forms of Arthritis are Curable
You Can Eliminate Osteoarthritis
By addressing the Underlying Causes through Clinical Trials and Studies

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to General health http://kylejnorton.blogspot.ca/p/general-health.html

Back to Kyle J. Norton Home page http://kylejnorton.blogspot.ca

References

(1) Green tea (-)epigallocatechin-3-gallate reverses oxidative stress and reduces acetylcholinesterase activity in a streptozotocin-induced model of dementia by Biasibetti R1, Tramontina AC, Costa AP, Dutra MF, Quincozes-Santos A, Nardin P, Bernardi CL, Wartchow KM, Lunardi PS, Gonçalves CA.(PubMed)

(2) Chronic epigallocatechin-3-gallate ameliorates learning and memory deficits in diabetic rats via modulation of nitric oxide and oxidative stress by Baluchnejadmojarad T1, Roghani M.(PubMed)

(3) Coffee, tea, and caffeine consumption and prevention of late-life cognitive decline and dementia: a systematic review by Panza F1, Solfrizzi V, Barulli MR, Bonfiglio C, Guerra V, Osella A, Seripa D, Sabbà C, Pilotto A, Logroscino G.(PubMed)

(4) Green tea aroma fraction reduces β-amyloid peptide-induced toxicity in Caenorhabditis elegans transfected with human β-amyloid minigene by Takahashi A1, Watanabe T, Fujita T, Hasegawa T, Saito M, Suganuma M.(PubMed)

(5) Plasma Carotenoids Are Inversely Associated With Dementia Risk in an Elderly French Cohort by Feart C1, Letenneur L2, Helmer C3, Samieri C2, Schalch W4, Etheve S4, Delcourt C2, Dartigues JF2, Barberger-Gateau P2.(PubMed)

(6) Lycopene modulates nitric oxide pathways against 3-nitropropionic acid-induced neurotoxicity by Kumar P1, Kalonia H, Kumar A.(PubMed)

(7) Effect of lycopene and epigallocatechin-3-gallate against 3-nitropropionic acid induced cognitive dysfunction and glutathione depletion in rat: a novel nitric oxide mechanism by Kumar P1, Kumar A.(PubMed)

(8) Chronic treatment with resveratrol, a natural polyphenol found in grapes, alleviates oxidative stress and apoptotic cell death in ovariectomized female rats subjected to chronic cerebral hypoperfusion by Ozacmak VH, Sayan-Ozacmak H, Barut F.(PubMed)

(9) The resveratrol trimer miyabenol C inhibits β-secretase activity and β-amyloid generation by Hu J1, Lin T2, Gao Y3, Xu J2, Jiang C2, Wang G2, Bu G3, Xu H1, Chen H2, Zhang YW3.(PubMed)

(10) Effects of resveratrol on apoptosis in a rat model of vascular dementia by Sun ZK1, Ma XR2, Jia YJ2, Liu YR2, Zhang JW1, Zhang BA2.(PubMed)

Most Common Diseases of elder: Upper respiratory tract infection(Respiratory Disease) – The Diseases associated to

Kyle J. Norton(Scholar and Master of Nutrients, all right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

                            Respiratory Disease 

Respiratory Disease is defined as medical conditions, affecting the breathing organ and tissues including Inflammatory lung disease, Obstructive lung diseases, Restrictive lung diseases, Respiratory tract infections, trachea, bronchi, bronchioles, alveoli, the nerves and muscles breathing , etc,.

                     Upper respiratory tract infection

Upper respiratory tract infections are considered to be the infection of the airway above the glottis or vocal cords. This includes the nose, sinuses, pharynx, and larynx, including the infection of tonsillitis, pharyngitis, laryngitis, sinusitis, etc,.

Diseases associated with Upper respiratory tract infection
1. Chlamydia infection
In humans the most common infections are caused by Chlamydophila pneumoniae is Chlamydia trachomatis.These pathogens are mainly responsible for infections of upper respiratory tract, infections of urinary tract and conjunctivitis(19).
2. Acute otitis media (AOM)
Acute otitis media (AOM) occurs as a complication of viral upper respiratory tract infections in young children. AOM and respiratory viruses both display seasonal variation. According to the study leaded by Department of Pediatrics, University of Utah Health Sciences Center, showed that During the study period, 96,418 respiratory viral tests were performed; 46,460 (48%) were positive. The most commonly identified viruses were: RSV (22%), rhinovirus (8%), influenza (8%), parainfluenza (4%), human metapneumovirus (3%), and adenovirus (3%). AOM was diagnosed during 271,268 ambulatory visits. There were significant associations between peak activity of RSV, human metapneumovirus, influenza A, and office visits for AOM. Adenovirus, parainfluenza, and rhinovirus were not associated with visits for AOM(20).
3. Streptococcus pneumoniae serotypes
Streptococcus pneumoniae serotypes associated with colonization of the upper respiratory tract in young children. According to the study by Medical University of Lublin of the 342 pneumococcal isolates, the serotype coverage by PCV-10 or PCV-13 was 73.7% or 80.1%, respectively. Moreover, 92.4% of the isolates belonged to serotypes included in the “old” 23-valent polysaccharide vaccine. A clear picture of the distribution of S. pneumoniae serotypes associated with colonization and/or infection in various geographical areas is needed in a light of recommended or routine vaccination(21).
4. Etc.
All Forms of Arthritis are Curable
You Can Eliminate Osteoarthritis
By addressing the Underlying Causes through Clinical Trials and Studies

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to General health http://kylejnorton.blogspot.ca/p/general-health.html

Back to Kyle J. Norton Home page http://kylejnorton.blogspot.ca
Sources
(19) http://www.ncbi.nlm.nih.gov/pubmed/22320048
(20) http://www.ncbi.nlm.nih.gov/pubmed/23249910
(21) http://www.ncbi.nlm.nih.gov/pubmed/23200561

The smoothie of Green Tea, Carrot and Strawberry for reduced Risk and Treatment of Fibroids back by Respectable Institutions

Kyle J. Norton(Scholar, Master of Nutrients), all right reserved.
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

The smoothie for reduced risk and Treatment of Eczema
Yield: 2 serving (about 8 ounce each)
11/4 cup strawberry
1/4 cup carrot
1 cup green tea drink (Make from 4 grams of green tea, and a cup of hot water lipped for 5 minutes. Set aside for cooling to room temperature)

1. Place all ingredients in a blender and puree about 1 minute
2. Blend on high speed about 1 minute or until the mixture is thick and the ice is well crushed. Add more green tea drink if needed
3. Serve immediately

The finding the natural ingredients for treatment of fibroids  is considered as a dream of many scientist to replace the long usage adverse effect of conventional medicine to other organs in the body. Unfortunately, many compounds found effective in initial studying failed to confirm the potential in large sample size and multi center.

Fibroids also known as uterine fibroids, is a condition of irregular cell growth of non cancerous tumor from the muscle layers of the uterus.
Recent studies suggested that scientist in some research centers have found the naturally potential ingredients, such as Green tea(1), Turmeric(3) and Olive(7) for reduced risk and treatment for

fibroids.
Green tea contains more amount of antioxidants than any drinks or food with the same volume, and is the leaves of Camellia sinensis, undergone minimal oxidation during processing, originated from China. Its phytochemical, epigallocatechin gallate (EGCG),  dramatically reduced the volume and weight of fibroids tumors at 4 and 8 weeks on rat leiomyoma (ELT3) cells in vitro and in a nude mice mode(1).

In a pilot randomized controlled clinical study, epigallocatechin gallate (EGCG) also inhibited the Uterine fibroids, significantly reduced fibroid-specific symptom severity as well as improved quality of life of patients(2).

Dr. Ozercan IH and the research team at the University of Firat said,"dietary supplementation with EGCG reduces the incidence and size of spontaneously occurring leiomyoma of the oviduct" in Japanese quail study(3).

Lycopene, a major phytochemical and antioxidant supplementation, found in tomato, exhibited a decreased incidence of leiomyomas in the oviduct of Japanese quail, according to the University of Firat(3).

According to Dr. Sahin K1 and research team at the Firat University, lycopene intake reduced risk leiomyomas (fibroids), benign tumors of the uterus affecting millions of women through its anti inflammatory activities in cell cycle arrest pathways(4).

In fact, in a 6627 incident cases of UL diagnosed by ultrasonography, dietary vitamin A is associated to reduce risk of uterine leiomyomata, according to the Slone Epidemiology Center at Boston University(5).

Flavonoid, a class of phytochemical found abundantly in strawberry, including apigenin and luteolin inhibited proliferation of of human leiomyomal smooth muscle cells, through significantly reduced cell numbers in culture, arrested cell proliferation, and induced cells apoptosis via down-regulated the IGF-I expression in growth hormone production(6).

Flavopiridol is a potent CDK inhibitor exhibited antiproliferative effect against Fibroids as flavonoid compound through cell cycle phase I arrest, according to the joint study lead by the Keimyung University School of Medicine(7).

The combined epigallocatechin gallate (EGCG), lycopene and apigenin and luteolin, found in green tea, carrot and strawberry respectively may contribute to further investigation of therapeutic natural ingredients for reduced risk and treatment of Fibroids

Women who are at increased risk of Fibroids due to family history, genetic mutation,... should drink at least one serving daily and women with Fibroids should drink as much as they can, depending to digestive toleration.

Made From Fresh Fruits And Vegetable Recipes
Secret To A Vibrant And Healthy Lifestyle
That You Can Find Easily At The Comfort Of Your Kitchen.

All Forms of Arthritis are Curable
You Can Eliminate Osteoarthritis
By addressing the Underlying Causes through Clinical Trials and Studies

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to General health http://kylejnorton.blogspot.ca/p/general-health.html

Back to Kyle J. Norton Home page http://kylejnorton.blogspot.ca

References
(1) Green tea extract inhibits proliferation of uterine leiomyoma cells in vitro and in nude mice by Zhang D1, Al-Hendy M, Richard-Davis G, Montgomery-Rice V, Sharan C, Rajaratnam V, Khurana A, Al-Hendy A.(PubMed)
(2) Treatment of symptomatic uterine fibroids with green tea extract: a pilot randomized controlled clinical study by Roshdy E1, Rajaratnam V, Maitra S, Sabry M, Allah AS, Al-Hendy A.(PubMed)
(3) Chemoprevention of fibroid tumors by [-]-epigallocatechin-3-gallate in quail by Ozercan IH1, Sahin N, Akdemir F, Onderci M, Seren S, Sahin K, Kucuk O.(PubMed)
(4) Lycopene supplementation prevents the development of spontaneous smooth muscle tumors of the oviduct in Japanese quail by Sahin K1, Ozercan R, Onderci M, Sahin N, Gursu MF, Khachik F, Sarkar FH, Munkarah A, Ali-Fehmi R, Kmak D, Kucuk O.(PubMed)
(5) Intake of fruit, vegetables, and carotenoids in relation to risk of uterine leiomyomata by Wise LA1, Radin RG, Palmer JR, Kumanyika SK, Boggs DA, Rosenberg L.(PubMed)
(6) Regulation of IGF-I production and proliferation of human leiomyomal smooth muscle cells by Scutellaria barbata D. Don in vitro: isolation of flavonoids of apigenin and luteolin as acting compounds by Kim DI1, Lee TK, Lim IS, Kim H, Lee YC, Kim CH.(PubMed)
(7) Antitumor effects of flavopiridol on human uterine leiomyoma in vitro and in a xenograft model by Lee HG1, Baek JW2, Shin SJ3, Kwon SH3, Cha SD3, Park WJ3, Chung R1, Choi ES3, Lee GH2, Cho CH4.(PubMed)

The Never failed Smoothie of Green Tea and Grape for Reduced Risk and Treatment of Colitis

Kyle J. Norton(Scholar, Master of Nutrients), all right reserved.
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.


The smoothie for reduced risk and treatment of colitis
Yield: 2 serving (about 8 ounce each)
1 1/2 cups grape

1 cup green tea drink (Make from 4 grams of green tea, and a cup of hot water lipped for 5 minutes. Set aside for cooling to room temperature)

1. Place all ingredients in a blender and puree about 1 minute
2. Blend on high speed about 1 minute or until the mixture is thick and the ice is well crushed. Add more green tea drink if needed
3. Serve immediately

The finding the natural ingredients for reduced risk and treatment of colitis without induced adverse effect  is considered as a dream of many scientist. Unfortunately, many compounds found effective in initial studying failed to confirm the potential in large sample size and multi center. Some even produce conflicted results in second and further studies.

Colitis is  a condition of inflammation of the large intestine, including the colon, cecum and rectum.

Recent studies by respectable institutions suggested that green tea(1) may be next potential ingredients for reduced risk and treatment of colitis. According to the joint study lead by the Universiti Putra Malaysia, Gallic acid, a biochemical found in green tea inhibited inflammatory bowel disease, through reduction of oxidative stress in in a dextran sulfate sodium (DSS)-induced mouse colitis model(1).

Green tea has been a precious drink in traditional Chinese culture and used exceptional in socialization for more than 4000 thousand years. Due to its commercial values and health effects, green tea now has been cultivated all over the world in suitable climate.

High dose of EGCG and green tea inhibited colitis in rodent model, but the effectiveness may be limited due to species differences in xenobiotic metabolism and microbiota, according to Dr. Martin DA and Dr. Bolling BW.(2).

In the finding of the method for controlling the symptoms of autoimmune chronic inflammatory bowel disease (IBD), in Colitis Models, Green tea (GrTP and EGCG) significantly restored ahepatic and colonic antioxidants levels and attenuated severity of colitis in comparison to sulfasalazine(3).

Procyanidins (ACT), a natural biologically active compound extracted from apple and grape seed, may also be next generation natural ingredient for treatment of colitis as it decreased the severity of selected markers of DSS-induced colitis in the distal ileum and proximal colon(5).

 In experimental models of colitis induced by dextran sulfate sodium (DSS) or oxazolone inhibited bowel inflammatory diseases through combined anti-inflammatory and immunomodulatory effects(4), according to the National Institute of Health Sciences, 1-18-1, Kamiyoga, Setagaya-ku, Tokyo.

Resveratrol, another biochemical found abundantly in grape exhibited anti chronic intestinal inflammatory disease, through its antioxidative defense against production of reactive oxygen species (ROS) and disturbed capacity(6), inflammatory cytokines as well as suppressed intestinal tumorigenesis through miRNA modulation(7).
The study by the Department of Food Science and Technology, CEBAS-CSIC said, "(oral administration of )different resveratrol prodrugs and pro-prodrugs did not develop colitis symptoms and improved 6-fold the disease activity index (DAI) compared to resveratrol"(8).
In support to the effectiveness of esveratrol, the University of Hong Kong study, suggested intragastric administration of 2,3',4,4',5'-pentamethoxy-trans-stilbene (PMS) (25, 50 mg.kg(-1) body weight), a derivative of resveratrol for 16 weeks significantly reduced the multiplicity of colonic neoplasms by 15% and 35% respectively(9).

This discover of the effectiveness of Green Tea and grape phytochemicals may serve as cornerstones of pharmaceutical target for further studies in production of a potential medication for reduced risk and treatment of colitis with little or no adverse effects.
People who are at high risk of colitis due to family history, obesity,..... should drink at least one serving daily and people with  colitis should drink the smoothie as much as they can, depending to digestive toleration.
Life style and dietary pattern change are recommended.

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References

(1) Gallic acid attenuates dextran sulfate sodium-induced experimental colitis in BALB/c mice by Pandurangan AK1, Mohebali N2, Norhaizan ME3, Looi CY2.(PubMed)

(2) A review of the efficacy of dietary polyphenols in experimental models of inflammatory bowel diseases by Martin DA1, Bolling BW.(PubMed)

(3) Green Tea Polyphenols and Sulfasalazine have Parallel Anti-Inflammatory Properties in Colitis Models by Oz HS1, Chen T, de Villiers WJ.(PubMed)

(4) Orally administered apple procyanidins protect against experimental inflammatory bowel disease in mice by Yoshioka Y1, Akiyama H, Nakano M, Shoji T, Kanda T, Ohtake Y, Takita T, Matsuda R, Maitani T.(PubMed)

(5) Grape seed extract reduces the severity of selected disease markers in the proximal colon of dextran sulphate sodium-induced colitis in rats by Cheah KY1, Bastian SE, Acott TM, Abimosleh SM, Lymn KA, Howarth GS.(PubMed)

(6) Resveratrol Pretreatment Ameliorates TNBS Colitis in Rats by Yildiz G, Yildiz Y, Ulutas PA, Yaylali A, Ural M1.(PubMed)

(7) Role of microRNAs in resveratrol-mediated mitigation of colitis-associated tumorigenesis in Apc(Min/+) mice by Altamemi I1, Murphy EA1, Catroppo JF1, Zumbrun EE1, Zhang J1, McClellan JL1, Singh UP1, Nagarkatti PS1, Nagarkatti M2.(PubMed)

(8) Preventive oral treatment with resveratrol pro-prodrugs drastically reduce colon inflammation in rodents by Larrosa M1, Tomé-Carneiro J, Yáñez-Gascón MJ, Alcántara D, Selma MV, Beltrán D, García-Conesa MT, Urbán C, Lucas R, Tomás-Barberán F, Morales JC,Espín JC.(PubMed)

(9) 2,3',4,4',5'-Pentamethoxy-trans-stilbene, a resveratrol derivative, inhibits colitis-associated colorectal carcinogenesis in mice by Li H1, Wu WK, Li ZJ, Chan KM, Wong CC, Ye CG, Yu L, Sung JJ, Cho CH, Wang M.(PubMed)