Tuesday, March 8, 2016

The Best Smoothie of Green Tea, Blueberry and Grape for Reduced Early Onset and Treatment of Liver Diseases

Kyle J. Norton(Scholar, Master of Nutrients), all right reserved.
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

The smoothie for prevention and treatment of  Liver disease
Yield: 2 servings (about 8 ounces each)
1 cup blueberry
1/2 cup grape
1 cup green tea drink (Make from 4 grams of green tea and a cup of hot water lipped for 5 minutes, and let cool to room temperature)

1. Place all ingredients in a blender and puree about 1 minute
2. Blend on high speed about 1 minute or until the mixture is thick and the ice is well crushed.
3. Serve immediately

The finding of a natural source for treatment of  Liver disease   has been running into many obstacles, many ingredients showed initially with promising result in animal studies have not produced same potentials in large sample size and mutli centers human trials.

Liver disease or hepatic disease is defined as a condition of damage of liver or inflammatory causes of diseases to the liver.
Recent reports of study back by renowned institutions, conveyed that green tea(1) may be holding a key for extracting natural ingredient for reduced early onset and treatment of liver diseases.

Green tea has been a precious drink in traditional Chinese culture and used exceptional in socialization for more than 4000 thousand years. Due to its commercial values and health effects, green tea now has been cultivated all over the world in suitable climate. According to the Saitama Cancer Center Research Institute,, regular intake of green tea drink is associated to protective effects against liver diseases(1).

In eight-week-old male C57BL/6J mice, fed a normal chow diet or high-fat diet (HFD) for 17 weeks, intake of pu-erh tea extract (PTE) ameliorated hepatic lipid metabolism, inflammation, and insulin resistance functions through by modulating hepatic IL-6/STAT3 signaling, the pro inflammatory pathway(2).
Dr. Yin X and colleagues at joint study lead by the Zhujiang Hospital of Southern Medical University, regardless of the race of the individual concerned where the Asian, American and European, green tea reduced risk of liver diseases, including hepatitis,hepatocellular carcinoma, liver steatosis, chronic liver disease,....(3).

Resveratrol, found abundantly in grape and blueberry,  is a plant-derived polyphenol with a potential as a food source to extend lifespan and healthspan in model organism. According to the University of Kansas Medical Center, the phytochemical exerted liver protective effects in xenobiotic-induced liver injury and other forms of liver injury(4). Also in acetaminophen hepatotoxicity causes of cause of acute liver injury and liver failure, resveratrol protected against Overdose of acetaminophen (APAP) hepatotoxicity through exhibiting antioxidant effects and preventing mitochondrial release of enzyme endonucleases and nuclear DNA damage(5).
Furthermore, the phytochemical may also be potential in reduced risk and treatment of liver fibrosis via the regulation of pro inflammatory, Akt/NF-κB pathways(6).

Pterostilbene, another antioxidant found in bluebrerry, used conjunction with resveratrol (RESV) expressed genotoxic and/or antigenotoxic effects through pro-apoptotic activity in HepG2 cells lines(7). Furthermore, pterostilbene also is potential against acetaminophen-induced hepatotoxicity(8), dimethylnitrosamine-induced liver fibrosis(9), plasma lipoproteins and cholesterol in hypercholesterolemic(10).

The finding of the effectiveness of Green Tea, Grape and Blue Berry may serve as cornerstones of pharmaceutical target for further studies as well as a potential medication for treatment of  Liver disease.

People who are at increased risk of  Liver disease, due to family history, alcohol drinking,....should drink the juices at least one a day. People with  Liver disease should drink the juice as much as  as they can depending to digestive toleration.
Life style and diet pattern change are recommended.

All Forms of Arthritis are Curable
You Can Eliminate Osteoarthritis
By addressing the Underlying Causes through Clinical Trials and Studies

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

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References
(1) Cross sectional study of effects of drinking green tea on cardiovascular and liver diseases by Imai K1, Nakachi K.(PubMed)
(2) Pu-erh tea extract ameliorates high-fat diet-induced nonalcoholic steatohepatitis and insulin resistance by modulating hepatic IL-6/STAT3 signaling in mice by Cai X1,2,3, Fang C2,4, Hayashi S2,3, Hao S5, Zhao M6, Tsutsui H2,3, Nishiguchi S7, Sheng J8.(PubMed)
(3) The effect of green tea intake on risk of liver disease: a meta analysis by Yin X1, Yang J2, Li T3, Song L4, Han T5, Yang M1, Liao H1, He J1, Zhong X1.(PubMed)
(4) Critical review of resveratrol in xenobiotic-induced hepatotoxicity by McGill MR1, Du K2, Weemhoff JL2, Jaeschke H2.(PubMed)
(5) Resveratrol prevents protein nitration and release of endonucleases from mitochondria during acetaminophen hepatotoxicity by Du K1, McGill MR1, Xie Y1, Bajt ML1, Jaeschke H2.(PubMed)
(6) Resveratrol attenuates the progress of liver fibrosis via the Akt/nuclear factor-κB pathways by Zhang H1, Sun Q1, Xu T1, Hong L1, Fu R1, Wu J1, Ding J1.(PubMed)
(7) In Vitro Safety/Protection Assessment of Resveratrol and Pterostilbene in a Human Hepatoma Cell Line (HepG2) by Lombardi G, Vannini S, Blasi F, Marcotullio MC, Dominici L, Villarini M, Cossignani L, Moretti M(PubMed)
(8) Protective effects of pterostilbene against acetaminophen-induced hepatotoxicity in rats by El-Sayed el-SM1, Mansour AM, Nady ME.(PubMed)
(9) Pterostilbene inhibits dimethylnitrosamine-induced liver fibrosis in rats by Lee MF1, Liu ML, Cheng AC, Tsai ML, Ho CT, Liou WS, Pan MH.(PubMed)
(10) Pterostilbene, a new agonist for the peroxisome proliferator-activated receptor alpha-isoform, lowers plasma lipoproteins and cholesterol in hypercholesterolemic hamsters by Rimando AM1, Nagmani R, Feller DR, Yokoyama W.(PubMed)

Most Common Diseases of elder: Lower respiratory tract infection (Respiratory Disease) – Pneumonia - The Antioxidants

Kyle J. Norton(Scholar and Master of Nutrients, all right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

                            Respiratory Disease 

Respiratory Disease is defined as medical conditions, affecting the breathing organ and tissues including Inflammatory lung disease, Obstructive lung diseases, Restrictive lung diseases, Respiratory tract infections, trachea, bronchi, bronchioles, alveoli, the nerves and muscles breathing , etc,.

                     Lower respiratory tract infection


The lower respiratory tract infection are the infection consisting of the trachea (wind pipe), bronchial tubes, the bronchioles, and the lungs, including the bronchitis and pneumonia. According to The World Health Report 2004 – Changing History(1), in 2002 lower respiratory track infection were still the leading cause of deaths among all infectious diseases, and accounted for 3.9 million deaths worldwide and 6.9% of all deaths that year.

                                      Pneumonia


Pneumonia is a condition of the inflammation of the lung as a result of infection, caused by bacteria, such as bacteria Streptococcus pneumoniae or influenza viruses in most cases. Fungi, such as Pneumocystis jiroveci, certain medication such as PPI Stomach Acid Drugs and other conditions such as impaired immune systems can also induced the disease.

                                  Prevention

 Antioxidants to prevent pneumonia
1. Hyperbaric oxygenation as antioxidant
In the study to use Hyperbaric oxygenation (HBO) in a complex intensive therapy of 194 children, aged 3 days to 3 years, with severe pneumonias, showed that initially the patients have revealed intensification of free radical processes (FRP) with a simultaneous decrease in the level of enzyme and non-enzyme protection and a drastic increase in gluco- and mineralocorticoid adrenal function. HBO and antioxidants (unithiol and alpha-tocopherol) yielded excellent and good results (a drop in FRP level and activation of enzyme antioxidant protection) in 75.8% of patients. HBO was ineffective in 17% of cases, in 7.2% of patients signs of the developing oxygen intoxication have been revealed(65).
2. Vitamin D
In the study to determine the role of oral vitamin D supplementation for resolution of severe pneumonia in under-five children in Two hundred children [mean (SD) age: 13.9 (11.7) months; boys: 120] between 2 months to 5 years with severe pneumonia, showed that Short-term supplementation with oral vitamin D (1000-2000 IU per day for 5 days) has no beneficial effect on resolution of severe pneumonia in under-five children. Further studies need to be conducted with higher dose of Vitamin D or longer duration of supplementation to corroborate these findings(66).
3. Zinc
Diarrhoeal disorders and acute respiratory infections (ARIs), especially pneumonia, are the most common causes of death in low-income countries. According to teh study by the Departments of Community Medicine and Child Health, Christian Medical College, zinc supplementation had no overall effect on the duration of hospitalization or of clinical signs associated with severe infection in young children hospitalized for severe pneumonia in southern India. This finding differs from the results of 2 previously reported trials wherein zinc supplementation was associated with a shorter period of recovery from severe pneumonia. Given the conflicting results, further research in representative settings is required to help clarify the role of zinc in the treatment of severe pneumonia(67).
4. Vitamin-A, vitamin C, vitamin E, folic acid and zinc
In a cross-sectional and controlled clinical trial conducted in under-5 children to compare the effects of supplementation of five micronutrients (vitamin-A, vitamin C, vitamin E, folic acid and zinc) on the morbidity and on the duration of hospital stay in pneumonia, by Rangpur Medical College, found that the average duration of hospital staying was 6.75 days in intervention group and 7.75 days in control group (p<0.01). Chest indrawing and fast breathing disappeared earlier in the intervention group (p<0.01) suggesting that supplementation of micronutrients decrease the morbidity and duration of hospital stay of children suffering from pneumonia(68).
5. Etc.
All Forms of Arthritis are Curable
You Can Eliminate OsteoarthritisBy addressing the Underlying Causes through Clinical Trials and Studies

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How ToPermanently Eliminate All Types of Ovarian Cysts Within 2 Months

Super foods Library, Eat Yourself Healthy With The Best of the Best Nature Has to Offer
Sources
(65) http://www.ncbi.nlm.nih.gov/pubmed/1862993
(66) http://www.ncbi.nlm.nih.gov/pubmed/21992858
(67) http://www.ncbi.nlm.nih.gov/pubmed/16685051
(68) http://www.ncbi.nlm.nih.gov/pubmed/18946457

Monday, March 7, 2016

The Impossible Smoothie of Brazil Nut, Flax Seed and Honey For Prevention and Treatment of Chronic Kidney disease

Kyle J. Norton(Scholar, Master of Nutrients), all right reserved.
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

The smoothie for prevention and treatment of Chronic Kidney disease
Yield: 2 servings (about 8 ounces each)
1/ 2 Brazil nut
1/2 flax seed
1/2 honey
1 cup rice milk

1. Place all ingredients in a blender and puree about 1 minute
2. Blend on high speed about 1 minute or until the mixture is thick and the ice is well crushed.
3. Serve immediately

The finding of a natural source for treatment of Chronic Kidney disease  has been running into many obstacles, many ingredients showed initially with promising result in animal studies have not produced same potentials in large sample size and mutli centers human trials.

Chronic Kidney disease is defined as a condition of the progression loss of kidney function over period of many years. Stage of chronic kidney disease according to the National Kidney Foundation's Kidney Disease Outcomes Quality Initiative (KDOQ). According to the George Institute for Global
Health, The presence of antioxidant may induced some benefits, particularly in those on dialysis(1).
Dr. Zachara BA said, "Oxidative stress plays a key role in numerous disease processes including chronic kidney disease (CKD). In general, oxygen metabolism leads to the formation of reactive oxygen species (ROS) dangerous to cells"(2).
Selenium, found abundantly in Brazil nut, was effectively in ameliorated oxidative stress and inflammation in hemodialysis (HD) patients, after 12 months through attenuated 8-isoprostane, 8-OHdG, the free radicals and cytokines, increased and the activity of GPx and expressed selenium plasma levels(3).
According to the Federal University of Rio de Janeiro (UFRJ), hemodialysis (HD) patients may be benefits in consumption of only one Brazil nut per day in 3 months as the study insisted that the procedure not only is effective against the inflammation, oxidative stress markers, and the atherogenic risk, but also improved the antioxidant defenses in HD patients(4).

Honey, the rich golden liquid is the miraculous product made by bees using nectar from flowers. It is considered as one of healthy sweet food for replacing the use of white sugar and artificial sweetener by many people. may also process the property as an antioxidant in reduced the expression of oxidative stress.  According to the Universiti Sains Malaysia, "administered alone or in combination with conventional therapy, honey might be a novel antioxidant in the management of chronic diseases commonly associated with oxidative stress"(5).
Dr,. Johnson DW and colleagues suggested, honey may also be effective against antibiotic-resistant microorganisms induced hemodialysis catheters infection of HD patients, topically(6).

Omega 3 fatty acids found abundantly in flax seed may be used conjunction with a cholesterol-lowering medication atorvastatin for treatment of chronic kidney disease (CKD)(7).
treatment of omega-3 FA-supplemented group after 6 months expressed a clinical benefit of increased vitamin D, fetuin-A levels, and modified erythrocyte membrane FA contents in dialysis patients of that reduced risk complications of vascular calcification and cardiovascular disease(8).


The finding of the effectiveness of Brazil Nut, Flax Seed and Honey may serve as cornerstones of pharmaceutical target for further studies as well as a potential medication for treatment of Chronic Kidney disease.

People who are at increased risk of Chronic Kidney disease, due to family history, obesity, diabetes,....should drink the juices at least one a day. People with Chronic Kidney disease. should drink the juice as much as  as they can depending to digestive toleration.

All Forms of Arthritis are Curable
You Can Eliminate Osteoarthritis
By addressing the Underlying Causes through Clinical Trials and Studies

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to General health http://kylejnorton.blogspot.ca/p/general-health.html

Back to Kyle J. Norton Home page http://kylejnorton.blogspot.ca




References
(1) Antioxidants for chronic kidney disease by Jun M1, Venkataraman V, Razavian M, Cooper B, Zoungas S, Ninomiya T, Webster AC, Perkovic V.(PubMed)
(2) Selenium and selenium-dependent antioxidants in chronic kidney disease by Zachara BA1.(PubMed)
(3) A follow-up study of the chronic kidney disease patients treated with Brazil nut: focus on inflammation and oxidative stress by Stockler-Pinto MB1, Malm O, Moraes C, Farage NE, Silva WS, Cozzolino SM, Mafra D.(PubMed)
(4) Brazil nut (Bertholletia excelsa, H.B.K.) improves oxidative stress and inflammation biomarkers in hemodialysis patients. by Stockler-Pinto MB1, Mafra D, Moraes C, Lobo J, Boaventura GT, Farage NE, Silva WS, Cozzolino SF, Malm O.(PubMed)
(5) Honey: a novel antioxidant by Erejuwa OO1, Sulaiman SA, Ab Wahab MS.(PubMed)
(6) Randomized, controlled trial of topical exit-site application of honey (Medihoney) versus mupirocin for the prevention of catheter-associated infections in hemodialysis patients by Johnson DW1, van Eps C, Mudge DW, Wiggins KJ, Armstrong K, Hawley CM, Campbell SB, Isbel NM, Nimmo GR, Gibbs H.(PubMed)
(7) Patient with hypertriglyceridemia, type 2 diabetes, and chronic kidney disease treated with atorvastatin andomega-3 Fatty Acid ethyl esters by Athyros VG1, Mikhailidis DP.(PubMed)

Most Common Diseases of elder: Lower respiratory tract infection (Respiratory Disease) – Pneumonia – The Diagnosis

Kyle J. Norton(Scholar and Master of Nutrients, all right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

                            Respiratory Disease 

Respiratory Disease is defined as medical conditions, affecting the breathing organ and tissues including Inflammatory lung disease, Obstructive lung diseases, Restrictive lung diseases, Respiratory tract infections, trachea, bronchi, bronchioles, alveoli, the nerves and muscles breathing , etc,.

                     Lower respiratory tract infection


The lower respiratory tract infection are the infection consisting of the trachea (wind pipe), bronchial tubes, the bronchioles, and the lungs, including the bronchitis and pneumonia. According to The World Health Report 2004 – Changing History(1), in 2002 lower respiratory track infection were still the leading cause of deaths among all infectious diseases, and accounted for 3.9 million deaths worldwide and 6.9% of all deaths that year.

                                      Pneumonia


Pneumonia is a condition of the inflammation of the lung as a result of infection, caused by bacteria, such as bacteria Streptococcus pneumoniae or influenza viruses in most cases. Fungi, such as Pneumocystis jiroveci, certain medication such as PPI Stomach Acid Drugs and other conditions such as impaired immune systems can also induced the disease.

                                           The Diagnosis

Diagnosis is totally dependent to the causes of the diseases by determining whether the cause of CAP is a bacterium, atypical bacterium, or virus. If you are experience some of the above symptoms and if your doctor suspects that you have restrictive lung function, after recording your family history and completing the physical exam, the test which your doctor orders include
1. Chest X-rays
X-rays can detemine the presence of pneumonia and the location of the infection. In the study to investigate the relation between physicians’ predicted probabilities of pneumonia and their utilities for ordering chest x-rays to detect pneumonia, the authors studied 52 physicians who ordered chest x-rays of 886 patients presenting to an emergency department with fever or respiratory complaints, found that physicians who experienced greater regret over missing a pneumonia than over ordering an unnecessary x-ray estimated lower probabilities of pneumonia for patients for whom they ordered x-rays.(53).
2. Blood test
The aim of the blood test is to measure your white cell count and look for the presence of viruses, bacteria or other organisms of which have caused the infection. According to the study by University of Florida, monitoring WBC concentration is a useful approach for early detection of infected foals on farms with a high prevalence of R equi pneumonia. In contrast, serologic surveillance by use of an AGID assay is of little benefit for that purpose(54).
3. Mucus tests
The aim of the test is to determine types of microorganism which cause the diseases
4. Etc.

All Forms of Arthritis are Curable
You Can Eliminate OsteoarthritisBy addressing the Underlying Causes through Clinical Trials and Studies

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How ToPermanently Eliminate All Types of Ovarian Cysts Within 2 Months

Super foods Library, Eat Yourself Healthy With The Best of the Best Nature Has to Offer
Sources


(53) http://www.ncbi.nlm.nih.gov/pubmed/1538630
(54) http://www.ncbi.nlm.nih.gov/pubmed/12675301

Sunday, March 6, 2016

The Tasty Smoothie of Broccoli and Cooked Tomato for Prevention and Treatment of Jaundice

Kyle J. Norton(Scholar, Master of Nutrients), all right reserved.
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

The smoothie for prevention and treatment of  Jaundice

Yield: 2 servings (about 8 ounces each)
1/2 cup broccoli
1 cup tomato
1 cup rice milk

1. Place all ingredients in a blender and puree about 1 minute
2. Blend on high speed about 1 minute or until the mixture is thick and the ice is well crushed.
3. Serve immediately

The finding of a natural source for reduced risk and treatment of Jaundice has encountered many obstacles, many ingredients showed initially the promising result in animal studies have not produced same potentials in either large sample size and mutli centers human trials.

Recent study from some well known institutions suggested that combination of Broccoli(1) and fennel(4) and celery(8) may hold a key for a natural ingredients for reduced painful symptoms and treatment of Jaundice.
Alpha-lipoic acid, found abundantly in Broccoli, exhibited liver protective effects against the development of jaundice hepatitis, cirrhosis, and hepatic coma,...(1).
Jaundice is a condition of yellowish pigmentation of the skin and the whites of the eye as a result of either the body is producing too much, or not getting rid of bilirubin in the fat layer under the skin
fast enough due to conditions of liver or gallbladder.

According to the Tabriz University of Medical Sciences, lipoic acid (LA) intake significantly attenuated the liver and intestine damage and injure and morbidity and mortality in in patients with obstructive jaundice during biliary tract surgery(2).
In support of the effectiveness of lipoic acid use for treatment of jaundice, Dr.Lyzogub VH and research team insisted, the liver protective effects of LA also include, "improved liver circulation and treated chronic liver diseases, such as cirrhosis, and hepatic coma, to treat diabetes, and diabetic neuropathy to alter carbohydrate metabolism, atherosclerosis, coronary atherosclerosis and many others disease"(3).

Lycopene, found abundantly in tomato may also be beneficiary for prevention and treatment of jaundice. According to the University of Hacettepe, frequent intake of lycopene significantly ameliorated the DNA damage, and improved the liver and kidney tissue injuries in rats with obstructive jaundice(4), probably through its liver protective and antioxidant properties(5).

The Smoothie of Broccoli and cooked Tomato may hold a key for further studies in production of a curable natural remedy for prevention and treatment of Jaundice.
.
People who are at  increased risk of Jaundice due to family history, weaken liver function,....should drink at least one cup or more daily. People with Jaundice may drink as much as they can, depending to the digestive toleration.


References
(1) [Application of alpha-lipoic acid in clinical practice].[Article in Ukrainian] by Lyzogub VH, Altunina NV, Bondarchuk OM.(PubMed)
(2) Lipoic acid prevents hepatic and intestinal damage induced by obstruction of the common bile duct in rats by Somi MH1, Kalageychi H, Hajipour B, Musavi G, Khodadadi A, Shokri N, Hashemi R, Bagheri I, Mutab Laleh F.(PubMed)
(3) [Application of alpha-lipoic acid in clinical practice].[Article in Ukrainian] by Lyzogub VH, Altunina NV, Bondarchuk OM.(PubMed)
(4) Antioxidant and antigenotoxic effects of lycopene in obstructive jaundice by Aydın S1, Tokaç M, Taner G, Arıkök AT, Dündar HZ, Ozkardeş AB, Taşlıpınar MY, Kılıç M, Başaran AA, Başaran N.(PubMed)
(5) Hepatoprotective and antioxidant effects of lycopene in acute cholestasis by Tokaç M, Aydin S, Taner G, Özkardeş AB, Yavuz Taşlipinar M, Doğan M, Dündar HZ, Kiliç M, Başaran AA, Başaran AN.(PubMed)

The Smoothie of Green Tea, Mango and Grape for Reduced Risk and Treatment of HPV (Human Papilloma Virus)

Kyle J. Norton(Scholar, master of Nutrients, all right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.


The smoothie for Reduced risk and Treatment of  HPV (Human papilloma virus)
Yield: 2 serving (about 8 ounce each)
1 cup grape
1/2 cup mango or strawberry
1 cup green tea drink (Make from 4 grams of green tea, a slice of ginger and a cup of hot water lipped for 5 minutes, and let cool to room temperature)
1. Place all ingredients in a blender and puree about 1 minute
2. Blend on high speed about 1 minute or until the mixture is thick and the ice is well crushed. Add more green tea drink if needed
3. Serve immediately


The dream of finding the natural ingredient for prevention and treatment of HPV (Human Papilloma virus)without adverse effects in replacement of conventional medication has not been abated. Some ingredients have to discard because of not achieving the same potent results in human trials.

Scientist community may have found the smoothie(combined ingredients of garlic, olive and coconut oils) with potential and therapeutic value for reduced risk and treatment of  HPV (Human Papilloma virus) without adverse effects.

HPV (human papilloma virus) is a group of sexually transmitted virus which can cause infectious diseases and cancers. According to the disease prevention and control, 50% of sexually active people will have genital HPV at some time in their lives.

Green tea has been a precious drink in traditional Chinese culture and used exceptional in socialization for more than 4000 thousand years. Due to its commercial values and health effects, green tea now has been cultivated all over the world in suitable climate. According to the Creighton University, epigallocatechin gallate, theaflavins isolated from green tea may have a potential to prevent sexually transmitted infections caused by HPV (human papilloma virus)(1).

In External genital warts (EGWs), a common sexually transmitted infection caused by HPV, may be treated by green tea polyphenols due to its antioxidant, antiproliferative, antiviral, and antitumor properties(2).

Dr. Rosen T said," mechanisms of action (MOAs).of catechins in the treatment of EGWs and otherHPV-related conditions may be related to or associated with postulated or proven antiviral and immunostimulatory activity"(3).

Resveratrol is a phytochemical in the class of Stilbenoids, found abundantly in grape and blueberry.
According to the joint study lead by the Mahatma Gandhi Institute of Medical Sciences, resveratrol may be a effectively natural compounds against E6 oncoprotein of high risk HPV18(4).

C mimosoides Lamk methanol extracts F21 contained multiple phenolic compounds, such as resveratrol,significantly decreased the viability of all cervical cancer cell lines, including HPV(5).
Furthermore, in HeLa cells (HPV18 positive), as well as in CaSki and SiHa cell lines (HPV16 positive), resveratrol induced cell cycle phase I arrest in cervical cancer cells through apoptosis and autophagy(6).

Gallic acid is a phytochemical in the class of Phenolic acids, found abundantly in tea, mango, strawberries also inhibited HPV through its antioxidant effects. According to the joint study lead by the Xi'an Jiaotong University Health Science Center, gallic acid (GA), attenuated the proliferation of HPVep cells and exhibited significant specificity towards HPV-positive cells via apoptosis and upregulation of antigen p53(7).
In HPV type 16 (CaSki) or 18 (HeLa) cancer cell lines, inhibited CxCa cell proliferation by by inducing apoptosis(8).
Dr. You BR and researchers at the Chonbuk National University,also insisted that Gallic acid (GA) induced cell death through increased reactive oxygen species (ROS) level and GSH (glutathione) depleted cell number in HeLa cells(9).

The Smoothie of Green Tea, Mango and Grape  may hold a key for further studies in production of a curable natural remedy for prevention and treatment of  HPV (Human Papilloma virus)
.
People who are at  increased risk of HPV (Human Papilloma virus) due to family history, weaken immunity,....should drink at least one cup or more daily. People with HPV (Human Papilloma virus) may drink as much as they can, depending to the digestive toleration.

All Forms of Arthritis are Curable
You Can Eliminate Osteoarthritis
By addressing the Underlying Causes through Clinical Trials and Studies

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to General health http://kylejnorton.blogspot.ca/p/general-health.html

Back to Kyle J. Norton Home page http://kylejnorton.blogspot.ca

References
(1) Natural polyphenols: potential in the prevention of sexually transmitted viral infections by Date AA1, Destache CJ2(PubMed)
(2) Sinecatechins 10% ointment: a green tea extract for the treatment of external genital warts BY Gupta AK1, Daigle D2.(PubMed)
(3) Green tea catechins: biologic properties, proposed mechanisms of action, and clinical implications. by Rosen T1.(PubMed)
(4) In Silico Docking to Explicate Interface between Plant-Originated Inhibitors and E6 Oncogenic Protein of Highly Threatening Human Papillomavirus 18 by Kumar S1, Jena L1, Sahoo M1, Kakde M1, Daf S2, Varma AK3.(PubMed
(5) Cytotoxic effects of Phytophenolics from Caesalpinia mimosoides Lamk on cervical carcinoma cell lines through an apoptotic pathway by Palasap A1, Limpaiboon T, Boonsiri P, Thapphasaraphong S, Daduang S, Suwannalert P, Daduang J.(PubMed)
(6) Resveratrol induces cell death in cervical cancer cells through apoptosis and autophagy by García-Zepeda SP1, García-Villa E, Díaz-Chávez J, Hernández-Pando R, Gariglio P.(PubMed)
(7) Gallic acid induces apoptosis in human cervical epithelial cells containing human papillomavirus type 16 episomes by Shi L1,2, Lei Y1, Srivastava R2, Qin W3, Chen JJ2,4.(PubMed)
(8) Gallic acid enhancement of gold nanoparticle anticancer activity in cervical cancer cells. by Daduang J1, Palasap A, Daduang S, Boonsiri P, Suwannalert P, Limpaiboon T.(PubMed)
(9) Gallic acid inhibits the growth of HeLa cervical cancer cells via apoptosis and/or necrosis by You BR1, Moon HJ, Han YH, Park WH.(PubMed)

The Smoothie of Celery, Apple and Grape Juice for Prevention and Treatment of Gestational Hypertension

Kyle J. Norton(Scholar, Master of Nutrients), all right reserved.
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

The curable smoothie for reduced risk and treatment of Gestational Hypertension 
Yield: 2 servings (about 8 ounces each)
3/4 cup celery
3/4 apple with peel
1 cup organic grape drink

1. Place all ingredients in a blender and puree about 1 minute
2. Blend on high speed about 1 minute or until the mixture is thick and the ice is well crushed. Add more green tea drink if needed
3. Serve immediately

Gestational hypertension is a condition of  of elevated blood pressure in pregnancy, effecting 6% of all pregnancies.
The finding the natural ingredients for treatment of Gestational Hypertension is considered as a dream of many scientist to replace the long usage adverse effect of conventional medicine to other organs in the body.
Unfortunately, many compounds found effective in initial studying failed to confirm the potential in large sample size and multi center. According to study, hypertension in pregnancy reduced quality of life physically and psychologically(1).

Diet rich in fruits and vegetable and reduced intake of red meat, saturated fat and trans fat has shown to attenuated risk of hypertension(2). Recent study showed that celery(3) intake used conjunction with grape(10) and apple(8) may be the potential drink for prevention and treatment of hypertension.

Recent reports from numbers of well known institutions insisted, intake of celery, apple and berry may be the next generation ingredient to be used on prevention and treatment of Gestational Hypertension

Celery is a species of Apium graveolens, belongings to the family Apiaceae, cultivated all around the globe as a vegetable. According to Chronic administration of hexanic, methanolic, and aqueous-ethanolic extracts of celery seed effectively exhibited an antihypertensive activity in chronic treatment of elevated BP in tested animals(5).

Dr. Dianat M and the research team at the Ahvaz Jundishapur University of Medical Sciences said," hydro-alcoholic celery leaf extract on systolic blood pressure (SBP), heart rate (HR) and lipid profile in animals' model of hypertension induced by fructose"(5)
3‑n‑butylphthalide (NBP), an phytochemical found in celery seed used in traditional Chinese medicine exhibited significantly antihypertensive and attenuated progression of hypertensive effects through decreased oxidative stress and the expression of pro‑inflammatory cytokines(6). 

Apple is the pomaceous fruit of the apple tree, a species of the rose family Rosaceae. It is one of the most widely cultivated tree fruits. With phytochemical flavonoids, apple and its peel inhibited angiotensin converting enzyme (ACE) in promoted the development of high blood pressure, Dr Balasuriya N and Dr. Rupasinghe HP. Suggested(7)According to the Mount Sinai School of Medicine, "Flavonoid (found abundantly in fruits and vegetable)(9) intake has been inversely associated with mortality from coronary heart disease and stroke,..... Lowering blood pressure through increased dietary consumption of dietary antioxidants(such as flavonoid) may decrease the rate of end-organ damage that is secondary to hypertension"(8).

Resveratrol, a phytochemical in the class of Stilbenoids, found abundantly in grape expressed alterations in vascular responsiveness in spontaneously hypertensive rat in the development of hypertension(10). According to the joint study led by the The First Affiliated Hospital of Nanjing Medical University, also displayed the inhibition of trophoblast apoptosis through oxidative stress in preeclampsia-model rats(11).

The establishment of combined ingredients of Celery, Apple and Grape Juice in reduced risk and treatment of Gestational Hypertension may act as a cornerstone for in deep, large sample size and multi centers study to confirm its effectiveness.

Women who are at increased risk of Gestational Hypertensiondue to family history, obesity.....should drink at least one serving daily and women with Gestational Hypertension should drink no more than 4 servings a day, depending to digestive toleration.
Change of life style and diet pattern are also recommended.

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References
(1) Association between hypertension and quality of life in pregnancy by Patrícia Medeiros Falcão K1,2, Pedrozo Campos Antunes T3, do Nascimento Andrade Feitosa A1,3, Victor EG2, Nunes Alves de Sousa M1, de Abreu LC3,4,5,Vilar de Asis E1,3, Barros de Quental O1,3, Pinheiro Bezerra IM4,5, Azevedo de Freitas Junior H1.(PubMed)
(2) Fruit and Vegetable Consumption and the Incidence of Hypertension in Three Prospective Cohort Studies by Borgi L1, Muraki I2, Satija A2, Willett WC2, Rimm EB2, Forman JP2.(PubMed)
(3) The effect of hydro-alcoholic celery (Apiumgraveolens) leaf extract on cardiovascular parameters and lipid profile in animal model of hypertension induced by fructose by Dianat M1, Veisi A1, Ahangarpour A1, Fathi Moghaddam H1.(PubMed)
(4) Flavonoids from fruit and vegetables: a focus on cardiovascular risk factors by Toh JY1, Tan VM, Lim PC, Lim ST, Chong MF.(PubMed)
(5) The effect of hydro-alcoholic celery (Apiumgraveolens) leaf extract on cardiovascular parameters and lipid profile in animal model of hypertension induced by fructose by Dianat M1, Veisi A1, Ahangarpour A1, Fathi Moghaddam H1.(PubMed)
(6) Protective effect of 3-n-butylphthalide against hypertensive nephropathy in spontaneously hypertensive rats by Zhu J1, Zhang Y1, Yang C1.(PubMed)
(7) Antihypertensive properties of flavonoid-rich apple peel extract by Balasuriya N1, Rupasinghe HP.(PubMed)
(8) Dietary flavonoids and hypertension: is there a link? by Moline J1, Bukharovich IF, Wolff MS, Phillips R.(PubMed)
(9) Antihypertensive effects of the flavonoid quercetin by Perez-Vizcaino F1, Duarte J, Jimenez R, Santos-Buelga C, Osuna A.(PubMed)
(10) Perinatal Resveratrol Supplementation to Spontaneously Hypertensive Rat Dams Mitigates the Development ofHypertension in Adult Offspring by Care AS1, Sung MM1, Panahi S1, Gragasin FS1, Dyck JR1, Davidge ST1, Bourque SL2.(PubMed)
(11) Resveratrol inhibits trophoblast apoptosis through oxidative stress in preeclampsia-model rats by Zou Y1, Zuo Q2, Huang S3, Yu X4, Jiang Z5, Zou S6, Fan M7, Sun L8.(PubMed)