Sunday, March 13, 2016

The Smoothie of Green Tea, Cinnamon and Strawberry for Prevention and Treatment of Scabies

Kyle J. Norton(Scholar, Master of Nutrients), all right reserved.
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

The smoothie for prevention and treatment of scabies
Yield: 2 servings (about 8 ounces each)
1 1/2 cups blueberry
1 tsp cinnamon
1 cup green tea drink (Make from 4 grams of green tea and a cup of hot water lipped for 5 minutes. Set aside for cooling to room temperature)

1. Place all ingredients in a blender and puree about 1 minute
2. Blend on high speed about 1 minute or until the mixture is thick and the ice is well crushed.
3. Serve immediately

The finding of a natural source for treatment of scabies has been running into many obstacles, many ingredients showed initially with promising result in animal studies have not produced same potentials in large sample size and mutli centers human trials.

Scabies is an itchy, highly contagious skin infestation caused by the mite Sarcoptes scabiei, accompanied with glomerulonephritis and rheumatic fever.

Green tea has been a precious drink in traditional Chinese culture and used exceptional in socialization for more than 4000 thousand years used in traditional Chinese medicine for treatment of variety of diseases, including cancers and heart diseases. According to the Taiyo Kagaku Co. Ltd, green tea polyphenols are effective in inhibited development and growth of bacterial spores in tested Bacillus bacteria(1).
Epidemiologically, green tea catechins exhibited antimicrobial effects against various pathogenic bacteria, including Escherichia coli(2), Propionibacterium Acnes, Propionibacterium Granulosum, Staphylococcus Aureus and Staphylococcus Epidermidis(3)

Cinnamon is a spice derived from the inner bark of tree, native to South East Asia, of over 300 species of the genus Cinnamomum, belongings to the family Lauraceae. The spice also processed anti microbial effect against many types of bacteria, including Listeria monocytogenes Scott A(4), L. monocytogenes, S. enterica(5), Escherichia coli and Staphylococcus aureus(6).

Strawberries is a genius of Fragaria × ananassa belongs to the family Roseaceae, grown all over the world with suitable climate for commercial profits and for health benefits.Its aqueous extracts exhibited anti microbial effect against the expression of the virulence factors of Vibrio cholerae strains(7), Staphylococcus bacteria. Salmonella bacteria(8).

Taking altogether, The combination of Green Tea, Cinnamon and Strawberry may offer the potential effect in prevention of the onset and treatment of Scabies, through their anti bacterial effect.
 People who are at increased risk of Scabies are wise to drink at least one serving daily. People with  Scabies, should drink the juice as much as they can, depending to the toleration of digestive system.

References
(1) Antimicrobial effects of green tea polyphenols on thermophilic spore-forming bacteria by Sakanaka S1, Juneja LR, Taniguchi M.(PubMed)
(2) Effects of green tea on Escherichia coli as a uropathogen. by Noormandi A1, Dabaghzadeh F1.(PubMed)
(3) Antimicrobial Activity of Pomegranate and Green Tea Extract on Propionibacterium Acnes, Propionibacterium Granulosum, Staphylococcus Aureus and Staphylococcus Epidermidis by Li Z, Summanen PH, Downes J, Corbett K, Komoriya T, Henning SM, Kim J, Finegold SM.(PubMed))
(4) Antimicrobial activity of clove and cinnamon essential oils against Listeria monocytogenes in pasteurized milk by Cava R1, Nowak E, Taboada A, Marin-Iniesta F.(PubMed)
(5) Effects of allspice, cinnamon, and clove bud essential oils in edible apple films on physical properties and antimicrobial activities by Du WX1, Olsen CW, Avena-Bustillos RJ, McHugh TH, Levin CE, Friedman M.(PubMed)
(6) Fabrication of electrospun polylactic acid nanofilm incorporating cinnamon essential oil/β-cyclodextrin inclusion complex for antimicrobial packaging by Wen P1, Zhu DH1, Feng K2, Liu FJ2, Lou WY2, Li N2, Zong MH3, Wu H4.(PubMed)
(7) Antimicrobial Effects of Blueberry, Raspberry, and Strawberry Aqueous Extracts and theirEffects on Virulence Gene Expression in Vibrio cholerae.by Khalifa HO1,2, Kamimoto M1, Shimamoto T1, Shimamoto T1.(PubMed)
(8) Berry phenolics selectively inhibit the growth of intestinal pathogens by Puupponen-Pimiä R1, Nohynek L, Hartmann-Schmidlin S, Kähkönen M, Heinonen M, Määttä-Riihinen K, Oksman-Caldentey KM.(PubMed)
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Most Common Diseases of elder: Respiratory Pleural disease: Pneumothorax - The Risk factors

Kyle J. Norton(Scholar and Master of Nutrients, all right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

                                          Respiratory Disease

Respiratory Disease is defined as medical conditions, affecting the breathing organ and tissues including Inflammatory lung disease, Obstructive lung diseases, Restrictive lung diseases, Respiratory tract infections, trachea, bronchi, bronchioles, alveoli, the nerves and muscles breathing , etc,.

                   Pleural disease: Pneumothorax

The pleura is a thin tissue covered by a layer of cells (mesothelial cells) that surrounds the lungs and lines the inside of the chest wall.
Pneumothorax is a condition of collection of air within the pleural cavity, from either the outside or from the lung of which affect the lung breathing.

The Risk factors

1. Gender, age and Influence of height
The risk of primary spontaneous pneumothorax was found to be greatest among persons 25 to 34 years old of each sex and greater for men than women, although a gradient of risk with increasing height was found which seemed to explain much of the male predominance in this condition(15).
2. Smoking
In the study of a sample consisted of 15,204 persons domiciled in the same circumscribed area (County of Stockholm). The annual incidence of first spontaneous pneumothorax (SP) in the admission area is 6/100,000 for women and 18/100,000 for men, showed that showed that smoking increased the relative risk of contracting a first spontaneous pneumothorax approximately ninefold among women and 22-fold among men and that there is a striking, statistically significant (p less than 0.001) dose-response relationship between smoking and the occurrence of SP(16).
3. Genetics
Certain genetic mutation in the family may increase risk of pneumothorax
a. N1303K mutation on CFTR gene
Bilateral pneumothorax is rarely seen and is a predictor of poor prognosis. There is a report of a newborn presenting with bilateral pneumothorax whose diagnosis was cystic fibrosis with N1303K mutation on CFTR gene(17).
b. BHD gene
Germline mutations of the BHD gene are involved in some patients with multiple lung cysts and pneumothorax(18).
c. FLCN gene
There is a report of a novel in-frame deletion mutation in FLCN gene in a Korean family with recurrent primary spontaneous pneumothorax(19).
4. Respiratory distress (RD)
In the study to describe respiratory distress (RD) in full-term neonates hospitalized in the NICU and to determine risk factors in this population for pneumothorax, indicated that RD at term exposes the infant to high morbidity and pneumothorax, especially if born outside of a level III maternity unit and absence of labor. http://www.ncbi.nlm.nih.gov/pubmed/22381669
5. A history of pneumothorax
People who has had one pneumothorax are at at increased risk of recurrent pneumothorax.
6. An illicit drug history
there is a report of a case of a 27-year-old man with an illicit drug history who presented with acute left-sided pleuritic chest pain and dyspnoea managed as for a spontaneous pneumothorax with aspiration and subsequent chest drain insertion following a chest radiograph(20).
6. Other risk factor
According to study, a history of smoking, the existence of comorbidities, previous surgery for ipsilateral spontaneous pneumothorax (ISP), and hand stitching increase the risk of postoperative recurrence of the diseases(21).


Sources
(17) http://www.hindawi.com/crim/pulmonology/2012/102196/
(18) http://www.ncbi.nlm.nih.gov/pubmed/15954507
(19) http://www.ncbi.nlm.nih.gov/pubmed/22576432
(20) http://www.ncbi.nlm.nih.gov/pubmed/22750841
(21) http://www.ncbi.nlm.nih.gov/pubmed/15928500
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The Best 50 plus Smoothie of Green Tea, Curcumin and Grape for Prevention and Treatment of Cervicitis

Kyle J. Norton(Scholar, Master of Nutrient, all right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

The smoothie for reduced risk and treatment of Cervicitis 
Yield: 2 servings (about 8 ounces each)
1 1/2  cups grape
1 tsp curcumin
1 cup green tea drink (Make from 4 grams of green tea, a slice of ginger and a cup of hot water lipped for 5 minutes, and let cool to room temperature)

1. Place all ingredients in a blender and puree about 1 minute
2. Blend on high speed about 1 minute or until the mixture is thick and the ice is well crushed. Add more green tea drink if needed
3. Serve immediately

The finding of a natural source for reduced risk and treatment of cervicitis to replace the conventional medicine has been running into many obstacles, many ingredients showed initially with promising result in animal studies have not produced same potentials in either large sample size and mutli centers human trials.
Cervicitis is an inflammation of the cervix.
Green tea has been a precious drink in traditional Chinese culture and used exceptional in socialization for more than 4000 thousand years. Due to its commercial values and health effects, green tea now has been cultivated all over the world in suitable climate.
According to the The Catholic University of Korea, green tea extracts (polyphenon E; poly E and (-)-epigallocatechin-3-gallate [EGCG]) exhibited anti human papilloma virus (HPV) infected cervical lesions at a a 200 mg of poly E taken orally every day for eight to 12 weeks(1).
The phytochemicals of epigallocatechin gallate and polyphenols E also inhibited immortalized HPV-immortalized cervical epithelial cells and cancer cell growth. induced apoptosis through cell cycle change, according Guangxi Medical University(2).

Turmeric is a perennial plant in the genus Curcuma, belonging to the family Zingiberaceae, native to tropical South Asia. Its phytochemical curcumin can stimulate prevention of multiple sexually transmitted infections of cervix caused by HIV (human immunodeficiency virus), HSV (herpes simplex virus) and HPV (human papilloma virus)(3).
According to the Air Force General Hospital of People's Liberation Army, curcumin induced apoptosis of HPV-positive human cervical cancer cells via the anti inflammatory/cellular tumor antigen NF-κB-p53-caspase-3 pathway(4).
In a phase II randomized controlled study,curcumin and curcumin containing polyherbal preparations have demonstrated anti-microbial and anti- viral properties against cervical human papillomavirus (HPV) infection(5).

Resveratrol is a phytochemical in the class of Stilbenoids, found abundantly in grape, etc. may also expressed immune modulating effects(6) against human papillomavirus (HPV)induced  inflammation(7) and malignant progression in neoplasms(8).

The effectiveness of  Green Tea, Curcumin and Grape may serve as cornerstones of pharmaceutical target for further studies in production of a potential medication for for Reduced Risk of Consequences of  cervicitis with little or no adverse effects.

Women who are at increased risk of Cervicitis due to sexual active,.... should take 1 - 2 servings daily and women with Cervicitis should take as much as they can depending to the digestive toleration.
Life style and dietary patter change are recommended.
References
(1) Protective effects of green tea extracts (polyphenon E and EGCG) on human cervical lesions by Ahn WS1, Yoo J, Huh SW, Kim CK, Lee JM, Namkoong SE, Bae SM, Lee IP.(PubMed)
(2) Green tea compound in chemoprevention of cervical cancer by Zou C1, Liu H, Feugang JM, Hao Z, Chow HH, Garcia F.(PubMed)
(3) Natural polyphenols: potential in the prevention of sexually transmitted viral infections by Date AA1, Destache CJ2.(PubMed)
(4) Curcumin improves the paclitaxel-induced apoptosis of HPV-positive human cervical cancer cells via the NF-κB-p53-caspase-3 pathway by Dang YP1, Yuan XY1, Tian R1, Li DG1, Liu W1.(PubMed)
(5) Clearance of cervical human papillomavirus infection by topical application of curcumin andcurcumin containing polyherbal cream: a phase II randomized controlled study by Basu P1, Dutta S, Begum R, Mittal S, Dutta PD, Bharti AC, Panda CK, Biswas J, Dey B, Talwar GP, Das BC.(PubMed)
(6) The enhancement of immune function and activation of NF-κB by resveratrol-treatment in immunosuppressive mice by Lai X1, Pei Q2, Song X1, Zhou X1, Yin Z3, Jia R4, Zou Y1, Li L1, Yue G5, Liang X1, Yin L1, Lv C1, Jing B1(PubMed)
(7) Regulation of immune responses to HPV infection and during HPV-directed immunotherapy by Bhat P1, Mattarollo SR, Gosmann C, Frazer IH, Leggatt GR.(PubMed)
(8) The role of human papilloma virus (HPV) infection in non-anogenital cancer and the promise of immunotherapy: a review by Cobos C1, Figueroa JA, Mirandola L, Colombo M, Summers G, Figueroa A, Aulakh A, Konala V, Verma R, Riaz J, Wade R, Saadeh C,Rahman RL, Pandey A, Radhi S, Nguyen DD, Jenkins M, Chiriva-Internati M, Cobos E.(PubMed)
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Most Common Diseases of elder: Respiratory Pleural disease: Pneumothorax - The Causes

Kyle J. Norton(Scholar and Master of Nutrients, all right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

                                          Respiratory Disease

Respiratory Disease is defined as medical conditions, affecting the breathing organ and tissues including Inflammatory lung disease, Obstructive lung diseases, Restrictive lung diseases, Respiratory tract infections, trachea, bronchi, bronchioles, alveoli, the nerves and muscles breathing , etc,.

                   Pleural disease: Pneumothorax

The pleura is a thin tissue covered by a layer of cells (mesothelial cells) that surrounds the lungs and lines the inside of the chest wall.
Pneumothorax is a condition of collection of air within the pleural cavity, from either the outside or from the lung of which affect the lung breathing.

The Causes
1. Chest injuries Severe thoracic, trauma to your chest can cause lung collapse. In the study to review CT scans and supine chest X-ray of 47 patients affected by severe thoracic, trauma, examined in 1985-86 and to compare the two methodologies in the assessment of pneumothorax, conducted by Ospedale Generale Regionale SS. Annunziata, indicated that CT detected 25 pneumothorax, whereas supine chest X-ray allowed a diagnosis in 18 cases only. In 8 of the latter (44.4%) the diagnosis was made possible by the presence of indirect signs of pneumothorax only–the most frequent being the deep sulcus sign(6).

2. Lung diseases causes of pneumothorax
a. Emphysema
Emphysema is also known as chronic obstructive pulmonary disease (COPD) involving
the destruction of lung tissue around the air sacs (alveoli) in the lungs. Secondary spontaneous pneumothorax is life-threatening for patients with pulmonary emphysema. There is a remarkable increase in the number of young patients who presented with lung emphysema and secondary spontaneous pneumothorax (SSP) at our institution for over a period of 30 months; most of them have a common history of marijuana abuse, according to the study by the University Hospital Berne(7).
b. Pneumonia
Pneumonia is defined as a condition of the inflammation of the lung as a result of infection, caused by bacteria, such as bacteria Streptococcus pneumoniae or influenza viruses in most cases. Fungi, such as Pneumocystis jiroveci, certain medication such as PPI Stomach Acid Drugs and other conditions such as impaired immune systems can also induced the disease. There is a report of a 7-year-old girl presented with subcutaneous emphysema, pneumomediastinum (PM), pneumoretroperitoneum, and pneumothorax caused by Mycoplasma pneumoniae (MP), according to the study by Nihon University Nerima-Hikarigaoka Hospital(8).

c. Cystic fibrosis
In the study to identify risk factors associated with pneumothorax and to determine the prognosis of CF patients following an episode of pneumothorax, showed that pneumothorax is a serious complication in CF patients, occurring more commonly in older patients with more advanced lung disease. Nearly 1 in 167 patients will experience this complication each year(9).

d. Lung cancer
There is a report of 2 cases of lung cancer incidentally detected following pneumothorax. d.1. Case 1:A 40-year-old man complaining of dyspnea was admitted with right pneumothorax. Chest computed tomography (CT) after chest drainage showed a cavitary nodule with pleural indentations in the right lower lobe. It was indicated at surgery that pneumothorax was caused by perforation of the tumor into the pleural cavity. d,2, Case 2:A 47-year-old man who admitted with right pneumothorax was found to have a nodule with pleural indentations closely a bulla at the apex of the right lung by chest CT after chest drainage. Pneumothorax was indicated to be caused by rupture of the bulla at surgery. Right upper lobectomy was performed because the pathological diagnosis of the nodule was a squamous carcinoma(10).
e. Pulmonary fibrosis
In the study to evaluate the relation between the severity of idiopathic pulmonary fibrosis (IPF) and the incidence of pneumothorax on computed tomography (CT) images, showed that pneumothorax in IPF patients is associated with lower VC and rapid deterioration of CT findings. The findings suggest that pneumothorax is a complication of advanced IPF(11).

f. Sarcoidosis
There is a report of four patients with sarcoidosis who developed pneumothorax. In one of the patients who had a thoracotomy, non-caseating granulomata were seen to be extensively involving the pleura. Whether pneumothorax and sarcoidosis are two independent processes occurring in the same individual or whether the pneumothorax is causally related to the sarcoidosis has not been determined.(12).

3. Ruptured visceral pleural bleb
Spontaneous pneumothoraces are believed to arise when air from the supplying airway exit via a ruptured visceral pleural bleb into the pleural cavity. Endobronchial one-way valves (EBVs) allow air exit (but not entry) from individual segmental airways(13).

4. Mechanical insufflation-exsufflation
Mechanical insufflation-exsufflation (MI-E) is a respiratory aid used by patients with weak respiratory muscles to increase cough peak flows and improve cough effectiveness. Relative contraindications to MI-E are said to include susceptibility to pneumothorax. There is a report of two cases of pneumothorax in patients with respiratory muscle weakness associated with daily use of MI-E: one was a 58-yr-old male with C4 ASIA C tetraplegia, and the other was a 26-yr-old male with Duchenne muscular dystrophy(14).

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Saturday, March 12, 2016

The Smoothie of Alfalfa Tea and Flax Seed for Delaying Symptom of Breast Ptosis Due to Aging

Kyle J. Norton(Scholar, Master of Nutrients), all right reserved.
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

The finding of a natural source for treatment of female breast ptosis has been running into many obstacles, many ingredients showed initially with promising result in animal studies have not produced same potentials in large sample size and mutli centers human trials.

Female breast ptosis is a natural occurring female breast sagging due to aging in reduced production of estrogen hormone.

The smoothie for delay Menopausal induction of  female breast ptosis due to aging
Yield: 2 servings (about 8 ounces each)
1 1/4 cups alfalfa tea (Make from 2 grams of dried alfalfa leave and sprout, and a cup of hot water lipped for 5 minutes, and let cool to room temperature. You can buy them at any health food store)
1/4 cup flax seed
1/2 cup of rice milk

1. Place all ingredients in a blender and puree about 1 minute
2. Blend on high speed about 1 minute or until the mixture is thick and the ice is well crushed. Add more green tea drink if needed
3. Serve immediately

The finding the natural ingredients for treatment of vasomotor symptoms, including breast ptosis  is considered as a dream of many scientist to replace the long term usage adverse effect of conventional medicine.
Unfortunately, many compounds found effective in initial studying failed to confirm the potential in large sample size and multi center.

Menopause is a condition in which a woman is in the transition stage of permanent cessation of the ovaries functions in egg production because of less production of estrogen and progesterone,signalling the end of the reproductive phrase a woman's life. In menopause, menstruation has become irregular and slowly stop overtime, but in some women, menstrual flow comes to a sudden halt.
Isoflavones found in legume, such as alfalfa leaf and sprout processed alleviating vasomotor episodes, attenuating bone loss, and stimulating vaginal epithelial maturation,. according to the joint study lead by The Chiang Mai University(1).

Dr.Sobenin IA and researcher at the Russian Cardiology Research and Production Complex, said, "Phytoestrogens are often considered as a possible alternative to hormone replacement therapy, since they are believed to alleviate some symptoms of menopause, such as, therosclerosis and atherosclerosis-related diseases through multiple mechanisms"(2).
In Fact, Phytoestrogens can play an important role in symptoms of menopause including fatigue, insomnia, problems with concentrations and depression symptoms and on women organism during menopausal period(3).


Levels of serotonin found abundantly in flax seed, is associated to reduced risk, frequency and severity of vasomotor symptoms in menopausal women(4). According to the Massachusetts General Hospital, serotonin-norepinephrine reuptake inhibitor duloxetine significant improve dpression, vasomotor symptoms, sleep, anxiety, and pain after 8 weeks(5).

Dr. Joffe H and the research team at the joint study lead Harvard Medical School, low-dose oral estradiol and venlafaxine(serotonin-norepinephrine reuptake inhibitor ) are effective treatments for VMS in women during midlife(6).

Another selective serotonin reuptake inhibitor, escitalopram, also alleviated the frequency, severity, and bother of menopausal hot flashes in the study of 205 women (95 African American; 102 white; 8 other) between July 2009 and June 2010.(7).

The combination of Alfalfa tea and Flax seed smoothie may hold a key in further studies in production of an effective natural ingredients for prevention and treatment of menopausal symptoms including breast ptosis without inducing adverse effects. Menopausal women should drink as much as they can, depending to the digestive toleration.

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References
(1) Short-Term Isoflavone Intervention in the Treatment of Severe Vasomotor Symptoms after Surgical Menopause: A Case Report and Literature Review by Teekachunhatean S1, Mattawanon N2, Khunamornpong S3.(PubMed)
(2) Phytoestrogen-Rich Dietary Supplements in Anti-Atherosclerotic Therapy in Postmenopausal Women by Sobenin IA1, Myasoedova VA, Orekhov AN.(PubMed)
(3) [Phytoestrogens--whether can they be an alternative to hormone replacement therapy for women during menopause period?].[Article in Polish] by Dittfeld A, Koszowska A, Brończyk AP, Nowak J, Gwizdek K, Zubelewicz-Szkodzińska B.(PubMed)
(4) Methods for the design of vasomotor symptom trials: the menopausal strategies: finding lasting answers to symptoms and health network by Newton KM1, Carpenter JS, Guthrie KA, Anderson GL, Caan B, Cohen LS, Ensrud KE, Freeman EW, Joffe H, Sternfeld B, Reed SD,Sherman S, Sammel MD, Kroenke K, Larson JC, Lacroix AZ.(PubMed)
(5) Treatment of depression and menopause-related symptoms with the serotonin-norepinephrine reuptake inhibitor duloxetine. by Joffe H1, Soares CN, Petrillo LF, Viguera AC, Somley BL, Koch JK, Cohen LS.(PubMed)
(6) Low-dose estradiol and the serotonin-norepinephrine reuptake inhibitor venlafaxine forvasomotor symptoms: a randomized clinical trial by Joffe H1, Guthrie KA2, LaCroix AZ2, Reed SD3, Ensrud KE4, Manson JE5, Newton KM6, Freeman EW7, Anderson GL2, Larson JC2, Hunt J2,Shifren J8, Rexrode KM5, Caan B9, Sternfeld B9, Carpenter JS10, Cohen L8(PubMed)
(7) Efficacy of escitalopram for hot flashes in healthy menopausal women: a randomized controlled trial. by Freeman EW1, Guthrie KA, Caan B, Sternfeld B, Cohen LS, Joffe H, Carpenter JS, Anderson GL, Larson JC, Ensrud KE, Reed SD, Newton KM, Sherman S, Sammel MD, LaCroix AZ.(PubMed)
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The Smoothie of Cooked Tomato, Peanut and Olive for reduced risk and Treatment of Juvenile nephronophthisis(polycystic kidney disease (Renal cystic disease))


 Kyle J. Norton(Scholar, Master of Nutrients), all right reserved.
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

Juvenile nephronophthisis is an inherited autosomal recessive disease, inducing multiple cysts at the corticomedullary junction and medulla in Juvenile around age of 13. According to Dr. Wolf MT, Nephronophthisis (NPHP) is an autosomal recessive cystic kidney disease and is one of the most common genetic disorders causing end-stage renal disease (ESRD) in children and adolescents(*).Therefore, smoothie with ingredients of Cooked Tomato, Peanut and Olive showed effectively in treatment of polycystic kidney disease, through clinical trials and studies, may also induce significant effect for treatment of Juvenile nephronophthisis.


The smoothie for prevention and treatment of  Juvenile nephronophthisis(polycystic kidney disease (Renal cystic disease))
Yield: 2 servings (about 8 ounces each)
3/4 cup cooked tomato
1/2 cup peanut
1/4 cup olive
1 cup rice milk

1. Place all ingredients in a blender and puree about 1 minute
2. Blend on high speed about 1 minute or until the mixture is thick and the ice is well crushed.
3. Serve immediately

The finding of a natural source for treatment of Polycystic kidney disease (Renal cystic disease) has been running into many obstacles, many ingredients showed initially with promising result in animal studies have not produced same potentials in large sample size and mutli centers human trials.

Polycystic Kidney Disease is an inherited diseases with fluid-filled cysts developed on the kidney. According to the University of Kansas Medical Center, the disease is associated to risk factors of aging, in older persons with multiple cysts probably induced by potassium deficiency, congenital disorders, metabolic diseases, and toxic renal injury(1).

Recent studies back by well known institutions proposed, Cooked Tomato, Peanut and Olive may be the next generation of natural ingredients for reduced complications and treatment of Polycystic kidney disease.

Vitamin B3 , also known as niacin, is a water-soluble vitamin.Vitamin B3 found abundantly in peanut may benefit patient with polycystic kidney disease(2). According to C.J. Janovy, administration of Vitamin B3 to a neonate, toddler or adolescent will effectively prevent or delay cyst formation and can be used for a lifetime(2).
Dr. Al Adlouni A and Dr. Hertig A. Said, "Vitamin B3 exhibited anti  autosomal dominant effect  involed the develop of polycystic kidney disease"(3).

Omaga 3 fatty acids found abundantly in flax seed also attenuated the progression of polycystic kidney disease, through alternation of multiple steps in PKD pathogenesis(4). According to the University of Guelph, mice fed with an n-3 fatty acid-enriched diet (MaxEPA) for 60 days, showed a marked decrease in the proportion of kidney area occupied by cysts in male but not in female rat(5).
Dr. Yamaguchi T and colleagues in the study led by the University of Manitoba, said,"Dietary flax oil may therefore reduce disease progression via mitigation of oxylipin abnormalities"(6) in patients with renal diseases.

Retinoic acids all-trans retinoic acid (AT-RA) and 9-cis retinoic acid (9C-RA) with function as of vitamin A suppressed the activation of the poly cystic kidney disease-1 (PKD1) promoter in's attenuated the diseases' progression(7). 
 Dr.Yamane A and professors at the Gunma University Graduate School of Medicine, said," A 63-year-old APL patient, complicated by Child-Pugh class A liver cirrhosis and polycystic kidney (creatinine 3.2 mg/dL), was successfully treated with 45 mg/m(2)/day of all-trans retinoic acid (ATRA)"(8).

The effectiveness of  Cooked Tomato, Peanut and Olive may serve as cornerstones of pharmaceutical target for further studies in production of a potential medication for reduced risk, complications and treatment of polycystic kidney disease (Renal cystic disease) with little or no adverse effects.

 Juvenile who are at high risk of nephronophthisis (polycystic kidney disease (Renal cystic disease)) due to aging, weaken renal function... should drink at least one serving daily and  Juvenile with nephronophthisis (polycystic kidney disease (Renal cystic disease)) should drink no more than 4 servings daily, depending to digestive toleration.

Life style and diet pattern change are necessary.



Refeneces
(* ) Nephronophthisis and related syndromes by Wolf MT1.(PubMed)
(1) Polycystic kidney disease: etiology, pathogenesis, and treatment by Martinez JR1, Grantham JJ.(PubMed)
(2) Vitamin B3 holds promise for treating polycystic kidney disease, research suggests, June 17, 2013
By C.J. Janovy
(3) [Vitamin B3 to prevent autosomal dominant polycystic kidney disease].[Article in French] by Al Adlouni A1, Hertig A2.(PubMed)
(4) Evidence for a role of proteins, lipids, and phytochemicals in the prevention of polycystic kidney disease progression and severity by Maditz KH1, Gigliotti JC, Tou JC.(PubMed)
(5) Effects of dietary supplementation with n-3 fatty acids on kidney morphology and the fatty acid composition of phospholipids and triglycerides from mice with polycystic kidney disease by Yamaguchi T1, Valli VE, Philbrick D, Holub B, Yoshida K, Takahashi H.(PubMed)
(6) Dietary flax oil rich in α-linolenic acid reduces renal disease and oxylipin abnormalities, including formation of docosahexaenoic acid derived oxylipins in the CD1-pcy/pcy mouse model of nephronophthisis by Yamaguchi T1, Devassy JG1, Gabbs M2, Ravandi A3, Nagao S4, Aukema HM5.(PubMed)
(7) Retinoic acid-dependent activation of the polycystic kidney disease-1 (PKD1) promoter by Islam MR1, Puri S, Rodova M, Magenheimer BS, Maser RL, Calvet JP.(PubMed)
(8) Successful treatment by all-trans retinoic acid in a patient with acute promyelocytic leukemia complicated by liver cirrhosis and polycystic kidney by Yamane A1, Tsukamoto N, Saitoh T, Uchiumi H, Handa H, Karasawa M, Nojima Y, Murakami H.(PubMed)


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Most Common Diseases of elder: Respiratory Pleural disease: Pneumothorax - The Symptoms

Kyle J. Norton(Scholar and Master of Nutrients, all right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

                            Respiratory Disease 

Respiratory Disease is defined as medical conditions, affecting the breathing organ and tissues including Inflammatory lung disease, Obstructive lung diseases, Restrictive lung diseases, Respiratory tract infections, trachea, bronchi, bronchioles, alveoli, the nerves and muscles breathing , etc,.
                     
                               Pleural disease: Pneumothorax

The pleura is a thin tissue covered by a layer of cells (mesothelial cells) that surrounds the lungs and lines the inside of the chest wall.
 Pneumothorax is a condition of collection of air within the pleural cavity, from either the outside or from the lung of which affect the lung breathing.

                                                                  Symptoms

The most common symptoms of Pneumothorax are
1. Chest pain and breathlessness
There is report of a 43-year-old man presented to his family physician with generalized pain over the right side of his chest following a harsh bout of coughing. The pain rapidly increased in severity over a period of 1 hour and also began radiating to his right arm. He also began to feel increasingly breathless. In view of the patient’s history, physical examination, and chest radiograph findings, a diagnosis of right-sided tension pneumothorax was made and urgent chest decompression was performed with a needle thoracostomy(1).
2. Dyspnoea
Dyspnoea, defined as an uncomfortable awareness of breathing ( difficult or labored breathing and shortness of breath), together with thoracic pain are two of the most frequent symptoms of presentation of thoracic diseases. According to the study, causes of dyspnoea are various and involve not only cardiovascular and respiratory systems, including pulmonary embolism, pneumothorax, and pulmonary edema(2).
3. Acute abdominal symptoms
There is a report of two cases of a 25 year-old and a 37 year-old male presenting with acute abdominal symptoms and later were both diagnosed as Pneumothorax(3)
4. Other symptoms
According to the study of a two-year-old male presented to the emergency department (ED) with a four-day history of evening tactile fevers, measured to 38.1ºC at home, associated with symptoms of a worsening cough, congestion, mild diarrhea, emesis, decreased oral intake and level of activity. A chest x-ray was obtained, which revealed a large right-sided pneumothorax with a leftward shift of the mediastinum(4).
According to the study to evaluated retrospectively in 219 patients, predominantly smokers who had had spontaneous pneumothorax, for the first time, indicated that moderate exertion was recorded in only 2%, and no patients were exerting themselves heavily when the symptoms began. The occurrence of spontaneous pneumothorax was unevenly (p less than 0.001) distributed over the day. In 9% the symptoms had their onset during quick movement–such as fastening a seat belt–without any effort(5)

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Sources
(1) http://www.ncbi.nlm.nih.gov/pubmed/15274663
(2) http://www.ncbi.nlm.nih.gov/pubmed/15220759
(3) http://www.ncbi.nlm.nih.gov/pubmed/20817498
(4) http://www.ncbi.nlm.nih.gov/pubmed/22973528
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