Thursday, March 17, 2016

The Smoothie of Tomato, Orange and Cooked Sweet Potato for Reduced Symptoms and Treatment of Variegate porphyria (VP)

Kyle J. Norton(Scholar, Master of Nutrients), all right reserved.
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

The smoothie for prevention and treatment of Variegate porphyria (VP)
Yield: 2 servings (about 8 ounces each)
3/4 cup tomato
3/4 cup cooked sweet potato
1 cup orange juice

1. Place all ingredients in a blender and puree about 1 minute
2. Blend on high speed about 1 minute or until the mixture is thick and the ice is well crushed.
3. Serve immediately

The finding of a natural source for treatment of Variegate porphyria (VP) has been running into many obstacles, many ingredients showed initially with promising result in animal studies have not produced same potentials in large sample size and mutli centers human trials.

Variegate porphyria (VP) is the result of decreased protoporphyrinogen oxidase (PPOX) in in biosynthesis of protoporphyrin IX activity and results in accumulation of porphyrins and porphyrin precursors. According to the Universitat de les Illes Balears, oral intake of vitamins E and C supplementation restores PPOX expression in VP patients and enhances antioxidants Glutathione reductase (GRd) and superoxide dismutase (SOD) activity, of that suggested potential benefits of a diet rich in vitamins E(found abundantly in Sweet Potato) and C (found abundantly Orange)in these patients(1).
Dr, Ferrer MD and professor at the Universitat de les Illes Balears insisted, dietary supplementation with vitamin E (50 mg/d) andvitamin C (150 mg/d) for 6 months decreased plasma oxidative damage and enhanced the erythrocyte activities of CAT and GR. in patients with variegate porphyria (VP)(2).

Canthaxanthin, one of two major carotenoids found in tomato, significantly improved 2 out of 5 patients with Variegate porphyria (VP) according to Dr, Eales L.(3).

The effectiveness of Tomato, Orange and Sweet Potato may serve as cornerstones of pharmaceutical target for further studies in production of a potential medication for prevention and  treatment of Variegate porphyria (VP) with little or no adverse effects.

People who are at high risk of Variegate porphyria (VP)  due to family history, genetic mutation, ..... should drink at least one serving daily and people with Variegate porphyria (VP)  should drink the smoothie as much as they can, depending to digestive toleration.
Life style and dietary patter change are recommended.


All Forms of Arthritis are Curable
You Can Eliminate Osteoarthritis
By addressing the Underlying Causes through Clinical Trials and Studies

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Super foods Library, Eat Yourself Healthy With The Best of the Best Nature Has to Offer recommended by Kyle J. Norton

Back to Kyle J. Norton Home page http://kylejnorton.blogspot.ca


References
(1) Antioxidants restore protoporphyrinogen oxidase in variegate porphyria patients. By Ferrer MD1, Tauler P, Sureda A, Palacín C, Tur JA, Pons A.(PubMed)
(2) Variegate porphyria induces plasma and neutrophil oxidative stress: effects of dietary supplementation with vitamins E and C. by Ferrer MD1, Tauler P, Sureda A, Palacín C, Tur JA, Pons A.(PubMed)
(3) The effects of canthaxanthin on the photocutaneous manifestations of porphyria. by Eales L.(PubMed)

Most Common Diseases of elder: Respiratory Pleural disease: Pneumothorax Treatment In traditional Chinese medicine perspective

Kyle J. Norton(Scholar and Master of Nutrients, all right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

                                          Respiratory Disease

Respiratory Disease is defined as medical conditions, affecting the breathing organ and tissues including Inflammatory lung disease, Obstructive lung diseases, Restrictive lung diseases, Respiratory tract infections, trachea, bronchi, bronchioles, alveoli, the nerves and muscles breathing , etc,.

                   Pleural disease: Pneumothorax

The pleura is a thin tissue covered by a layer of cells (mesothelial cells) that surrounds the lungs and lines the inside of the chest wall.
Pneumothorax is a condition of collection of air within the pleural cavity, from either the outside or from the lung of which affect the lung breathing.

                                                     Treatment


In traditional Chinese medicine perspective
A. Ting Li Zi is also known as Pepperweed/Tansymustard Seed. The acrid, bitter and cold herb has been used in TCM to treat whooping cough, pleurisy, idiopathic pneumothorax, pulmonary edema, ascites, acute nephritis, etc., by enhancing the functions of lung, heart, liver, stomach and bladder channels.
1. Phytotoxicity and antioxidant activity In the study to evaluate the possible in vitro phytotoxic effects of 27 flavonoids on the germination and early radical growth of Raphanus sativus L. and Lepidium sativum L., 2,2-Diphenyl-1-picrylhydrazyl (DPPH) test confirms the antioxidant activity of luteolin, quercetin, catechol, morin, and catechin. The biological activity recorded is discussed in relation to the structure of compounds and their capability to interact with cell structures and physiology. No correlation was found between phytotoxic and antioxidant activities(56).
2. Immunomodulatory activity
In the study to evaluate the immunomodulatory activity of protein extracts (PEs) of 14 Moroccan medicinal plants, found that the first group represented by Citrullus colocynthis, Urtica dioica, Elettaria cardamomum, Capparis spinosa and Piper cubeba showed a significant immunosuppressive activity. The second group that showed a significant immunostimulatory activity was represented by Aristolochia longa, Datura stramonium, Marrubium vulgare, Sinapis nigra, Delphynium staphysagria, Lepidium sativum, Ammi visnaga and Tetraclinis articulata(57).
3. Airways Disorders
in the study of Pharmacological Basis for the Medicinal Use of Lepidium sativum in Airways Disorders, indicated that bronchodilatory effect of Lepidium sativum is mediated through a combination of anticholinergic, Ca(++) antagonist and PDE inhibitory pathways, which provides sound mechanistic background for its medicinal use in the overactive airways disorders(58).
4. Antidiarrheal and antispasmodic activities
in the study to provide the pharmacological basis for the medicinal use of Lepidium sativum in diarrhea using in vivo and in vitro assays, found that Lepidium sativum seed extract possesses antidiarrheal and spasmolytic activities mediated possibly through dual blockade of muscarinic receptors and Ca(++) channels, though additional mechanism(s) cannot be ruled out and this study explains its medicinal use in diarrhea and abdominal cramps(59).
5. Side Effects
a. Do not use the herb in case of whooping cough and cough as a result of lung qi or spleen deficiency
b. Do not use the herb in newborn, children or if you are pregnant or breast feeding without first consulting with the related field specialist.
c. Etc.

B. Chuan Bei Mu
1. Antitussive, expectorant and anti-inflammatory activitiesIn the evaluation the antitussive, expectorant and anti-inflammatory effects of alkaloids – imperialine, imperialine-β-N-oxide, isoverticine, and isoverticine-β-N-oxide, which were isolated from BFW, found that the four alkaloids significantly inhibited cough frequency and increased latent period of cough in mice induced by ammonia. Imperialine and isoverticine showed obviously antitussive activities in a dose-dependent manner. Besides, the four alkaloids markedly enhanced mice’s tracheal phenol red output in expectorant assessment and significantly inhibited the development of ear edema in anti-inflammatory evaluation assay.
2. Side Effects
a. Raw Chuan Bei or Chuan Bei Mu is toxic
b. Do not use the herb in case of cough caused by spleen deficiency or cold with wet phlegm
c. Do not use the herb in newborn, children or if you are pregnant or breast feeding without approval from the related field specialist
d. Etc.

C. Bai He Gu Jin Wan
According to the JAKE FRATKIN’S COMPREHENSIVE INDEX OFCHINESE HERBAL PRODUCTS IN AMERICAAvailable GMP Products from United States, China and TaiwanJake Jake Paul Fratkin, OMD, L.Ac. in the section of 3A. 4. The formula is used to treat Chronic bronchitis, bronchiectasis, pharyngitis, spontanious pneumothorax, cor pulmonale, silicosis, pulmonary tuberculosis, ie. TB by enhancing the Lung and Kidney Yin with internal Dryness of the Lungs.Disease specificity, (subject to Syndrome Differentiation). with Contraindicated in Shi (Excess), including Exterior conditions and caution in cases with concomitant Spleen Qi Deficiency due to sticky nature of several herbs in this formula.

Wednesday, March 16, 2016

The Smoothie of Brazil Nut, Olive and Honey for Prevention and Treatment of Chronic Kidney disease, including Mesoamerican nephropathy

Kyle J. Norton(Scholar, Master of Nutrients), all right reserved.
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

The smoothie for prevention and treatment of Chronic Kidney disease, including Mesoamerican nephropathy
Yield: 2 servings (about 8 ounces each)
1/ 2 Brazil nut
1/2 olive
1/2 honey
1 cup water

1. Place all ingredients in a blender and puree about 1 minute
2. Blend on high speed about 1 minute or until the mixture is thick and the ice is well crushed.
3. Serve immediately

Mesoamerican nephropathy is a chronic kidney disease of unknown cause, emerging in the last decade in Central America, inducing chronic tubulointerstitial disease with associated secondary glomerulosclerosis and some signs of glomerular ischemia(9).

The finding of a natural source for treatment of  Mesoamerican nephropathy is a chronic kidney disease has been running into many obstacles, many ingredients showed initially with promising result in animal studies have not produced same potentials in large sample size and mutli centers human trials.

Chronic Kidney disease is defined as a condition of the progression loss of kidney function over period of many years. Stage of chronic kidney disease according to the National Kidney Foundation's Kidney Disease Outcomes Quality Initiative (KDOQ). According to the George Institute for Global
Health, The presence of antioxidant may induced some benefits, particularly in those on dialysis(1).
Dr. Zachara BA said, "Oxidative stress plays a key role in numerous disease processes including chronic kidney disease (CKD). In general, oxygen metabolism leads to the formation of reactive oxygen species (ROS) dangerous to cells"(2).

Selenium, found abundantly in Brazil nut, was effectively in ameliorated oxidative stress and inflammation in hemodialysis (HD) patients, after 12 months through attenuated 8-isoprostane, 8-OHdG, the free radicals and cytokines, increased and the activity of GPx and expressed selenium plasma levels(3).
According to the Federal University of Rio de Janeiro (UFRJ), hemodialysis (HD) patients may be benefits in consumption of Brazil nut  in 3 months as the study insisted that the procedure not only is effective against the inflammation, oxidative stress markers, and the atherogenic risk, but also improved the antioxidant defenses in HD patients(4).

Honey, the rich golden liquid is the miraculous product made by bees using nectar from flowers. It is considered as one of healthy sweet food for replacing the use of white sugar and artificial sweetener by many people. may also process the property as an antioxidant in reduced the expression of oxidative stress. According to the Universiti Sains Malaysia, "administered alone or in combination with conventional therapy, honey might be a novel antioxidant in the management of chronic diseases commonly associated with oxidative stress"(5).

Dr,. Johnson DW and colleagues suggested, honey may also be effective against antibiotic-resistant microorganisms induced hemodialysis catheters infection of HD patients, topically(6).

Omega 3 fatty acids found abundantly in olive may be used conjunction with a cholesterol-lowering medication atorvastatin for treatment of chronic kidney disease (CKD)(7).
treatment of omega-3 FA-supplemented group after 6 months expressed a clinical benefit of increased vitamin D, fetuin-A levels, and modified erythrocyte membrane FA contents in dialysis patients of that reduced risk complications of vascular calcification and cardiovascular disease.

In patient with Mesoamerican nephropathy, maintaining enough water intake to prevent heat stress, dehydration, biomarkers of renal function and their possible associations may reduced risk of decreased renal blood flow, high demands on tubular reabsorption, and increased levels of uric acid induced kidney damage in progression of kidney failure in sugarcane workers in Central America(9)(10)

The finding of the effectiveness of Brazil Nut, Olive and Honey may serve as cornerstones of pharmaceutical target for further studies as well as a potential medication for treatment of Chronic Kidney disease, including Mesoamerican nephropathy.

People who are at increased risk of Chronic Kidney disease, including Mesoamerican nephropathy, due to family history, obesity, diabetes,....should drink the juices at least one a day. People with Chronic Kidney disease, including Mesoamerican nephropathy. should drink the juice as much as as they can depending to digestive toleration.
All Forms of Arthritis are Curable

You Can Eliminate Osteoarthritis
By addressing the Underlying Causes through Clinical Trials and Studies

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to General health http://kylejnorton.blogspot.ca/p/general-health.html

Back to Kyle J. Norton Home page http://kylejnorton.blogspot.ca

References
(1) Antioxidants for chronic kidney disease by Jun M1, Venkataraman V, Razavian M, Cooper B, Zoungas S, Ninomiya T, Webster AC, Perkovic V.(PubMed)
(2) Selenium and selenium-dependent antioxidants in chronic kidney disease by Zachara BA1.(PubMed)
(3) A follow-up study of the chronic kidney disease patients treated with Brazil nut: focus on inflammation and oxidative stress by Stockler-Pinto MB1, Malm O, Moraes C, Farage NE, Silva WS, Cozzolino SM, Mafra D.(PubMed)
(4) Brazil nut (Bertholletia excelsa, H.B.K.) improves oxidative stress and inflammation biomarkers in hemodialysis patients. by Stockler-Pinto MB1, Mafra D, Moraes C, Lobo J, Boaventura GT, Farage NE, Silva WS, Cozzolino SF, Malm O.(PubMed)
(5) Honey: a novel antioxidant by Erejuwa OO1, Sulaiman SA, Ab Wahab MS.(PubMed)
(6) Randomized, controlled trial of topical exit-site application of honey (Medihoney) versus mupirocin for the prevention of catheter-associated infections in hemodialysis patients by Johnson DW1, van Eps C, Mudge DW, Wiggins KJ, Armstrong K, Hawley CM, Campbell SB, Isbel NM, Nimmo GR, Gibbs H.(PubMed)
(7) Patient with hypertriglyceridemia, type 2 diabetes, and chronic kidney disease treated with atorvastatin andomega-3 Fatty Acid ethyl esters by Athyros VG1, Mikhailidis DP.(PubMed)
(8)  CKD of unknown origin in Central America: the case for a Mesoamerican nephropathy by Correa-Rotter R1, Wesseling C2, Johnson RJ3.(PubMed)
(9) Heat stress, dehydration, and kidney function in sugarcane cutters in El Salvador--A cross-shift study of workers at risk of Mesoamerican nephropathy by García-Trabanino R1, Jarquín E2, Wesseling C3, Johnson RJ4, González-Quiroz M5, Weiss I6, Glaser J7, José Vindell J8, Stockfelt L9, Roncal C10, Harra T11(PubMed)
(10) Heat Stress Nephropathy From Exercise-Induced Uric Acid Crystalluria: A Perspective on MesoamericanNephropathy by Roncal-Jimenez C1, García-Trabanino R2, Barregard L3, Lanaspa MA1, Wesseling C4, Harra T1, Aragón A5, Grases F6, Jarquin ER7, González MA8, Weiss I9,Glaser J9, Sánchez-Lozada LG10, Johnson RJ11(PubMed)




Most Common Diseases of elder: Respiratory Pleural disease: Pneumothorax Treatment In conventional medicine perspective

Kyle J. Norton(Scholar and Master of Nutrients, all right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

                                          Respiratory Disease

Respiratory Disease is defined as medical conditions, affecting the breathing organ and tissues including Inflammatory lung disease, Obstructive lung diseases, Restrictive lung diseases, Respiratory tract infections, trachea, bronchi, bronchioles, alveoli, the nerves and muscles breathing , etc,.

                   Pleural disease: Pneumothorax

The pleura is a thin tissue covered by a layer of cells (mesothelial cells) that surrounds the lungs and lines the inside of the chest wall.
Pneumothorax is a condition of collection of air within the pleural cavity, from either the outside or from the lung of which affect the lung breathing.

                                                     Treatment

In conventional medicine perspective
A. Nonsurgical treatments
1. Obsercation
In most case, if the only a small portion of your lung is collapsed, the disease may be monitored with a series of X ray. Treatments only are necessary if the disease get worse. According to the study of St. Joseph’s Hospital & Medical Center of Sixteen trauma centers identified 588 OPTXs in 569 blunt trauma patients. One hundred twenty-one patients (21%) underwent immediate tube thoracostomy and 448 (79%), most blunt trauma patients with OPTX can be carefully monitored without tube thoracostomy; however, OPTX progression and respiratory distress are independently associated with observation failure(50).
2. Chest drain
In some cases, chest draining may be necessary, but adequate training for the insertion of chest drains in a trauma setting reduces the occurrence of procedure-related complications.According to the study by the Isala klinieken, locatie Sophia, afd. Heelkunde, Zwolle, for drainage of a traumatic pneumo- or haemothorax a large drain (28-36 French) is advised. The preferential insertion site is the 5th intercostal space in the midaxillary line. Drainage systems consist of a collection bottle, water seal and a suction control. Suction applied at 15-20 cm H2O is recommended for adequate drainage. Conversion to thoracotomy is determined by the drain production. Occult air leaks before removal of the drain can be detected by a temporary water seal or by clamping the drain followed by a chest X-ray(51).
3. Manual aspiration
In the study of 56 patients with baseline characteristics were similar, found that immediate success rates were 68.0% for Manual aspiration (MA) versus 80.6% for tube thoracostomy (TT) (p = 0.28). Two week success rates were 100% in both groups. There was a significant difference in hospital stay in favour of MA: 2.4 ± 2.6 versus 4.4 ± 3.3 days (p = 0.02). One year recurrence rates in MA were lower than in TT, although not statistically significant (4.0% and 12.9% p = 0.37). Predictors of immediate success were traumatic PTX and female sex. One patient died during follow-up due to heart failure. The study concluded that MA is simple, safe, cheap, minimal invasive in uncomplicated PSP/traumatic PTX with similar success and recurrence rates and a shorter hospital stay in comparison to TT and therefore the treatment of choice(52).
B. Surgery
1. Sealant
Pulmonary air leaks are common complications of lung resection and result in prolonged hospital stays and increased costs. In the study to investigate whether, compared with standard care, the use of a synthetic polyethylene glycol matrix (CoSeal®) could reduce air leaks detected by means of a digital chest drain system (DigiVent™), in patients undergoing lung resection (sutures and/or staples alone), showed that The use of CoSeal® may decrease the occurrence and severity of postoperative air leaks after lung resection and is associated with shorter hospital stay(53).
2. Thoracoscopy
In the study to review our experience of video-assisted thoracoscopic apical pleurectomy and to evaluate whether suction or water seal is superior in the postoperative treatment of primary spontaneous pneumothorax, indicated that Video-assisted thoracoscopic apical pleurectomy is effective and safe for treating primary spontaneous pneumothorax. Placing chest tubes on water seal after a brief period of suction shortens the duration of chest tube placement and hence the hospital stay(54)
2. Pleurodesis
is a surgical procedure in removing the entire pleural space and attaches the lung to the chest wall, permanently. In the study to compare the efficacy and safety between apical pleurectomy and pleural abrasion with minocycline in primary spontaneous pneumothorax (PSP) with high recurrence risk, showed that Pleural abrasion with minocycline pleurodesis is as effective as apical pleurectomy and either technique is appropriate for treating PSP patients with high recurrence risk. This trial was registered at http://www.clinicaltrials.gov (ID: NCT00270751)(55).

Sources
(50) http://www.ncbi.nlm.nih.gov/pubmed/21610419
(51) http://www.ncbi.nlm.nih.gov/pubmed/19818184
(52) http://www.ncbi.nlm.nih.gov/pubmed/22925840
(53) http://www.ncbi.nlm.nih.gov/pubmed/23043755
(54) http://www.ncbi.nlm.nih.gov/pubmed/12735584
(55) http://www.ncbi.nlm.nih.gov/pubmed/22323011

The 50 plus Women Smoothie of Green Tea, Sweet Potato and Flax Seed for Reduced Risk and Treatment of Atrophic Vaginitis

Kyle J. Norton(Scholar, Master of Nutrients), all right reserved.
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

The Incredible and Effective smoothie for Reduced Risk of consequences of Atrophic Vaginitis  in Pregnancy
Yield: 2 servings (about 8 ounces each)
1 1/4  cup sweet potato
1/4 cup flax seed
1 cup green tea drink (Make from 4 grams of green tea, a slice of ginger and a cup of hot water lipped for 5 minutes, and let cool to room temperature)
1. Place all ingredients in a blender and puree about 1 minute
2. Blend on high speed about 1 minute or until the mixture is thick and the ice is well crushed.
3. Serve immediately

Atrophic Vaginitis is an inflammation of the vagina and the outer urinary tract due to decreased production of estrogen induced thinning and shrinking of the tissues, and decreased lubricationas a result of aging in women..

The finding of a natural source for reduced risk and treatment of Atrophic Vaginitis to replace the oral hormone replacement therapy (HRT), has been running into many obstacles, many ingredients showed initially with promising result in animal studies have not produced same potentials in either large sample size and mutli centers human trials.

Strong evidences of number of renowned institutions suggested that natural sources, including a gel, containing hyaluronic acid(1)(8), liposomes,phytoestrogens from Humulus lupulus extract, and Vitamin E, may be effective for treatment of Atrophic Vaginitis applied topically (1).

Dr.Sobenin IA and researcher at the Russian Cardiology Research and Production Complex, said, "Phytoestrogens are often considered as a possible alternative to hormone replacement therapy, since they are believed to alleviate some symptoms of menopause, such as, therosclerosis and atherosclerosis-related diseases through multiple mechanisms"(2).
In Fact, Phytoestrogens can play an important role in symptoms of menopause including fatigue, vigina dryness, insomnia, problems with concentrations and depression symptoms and on women organism during menopausal period(3).

Levels of serotonin found abundantly in flax seed, is associated to reduced risk, frequency and severity of vasomotor symptoms in menopausal women(4). According to the Massachusetts General Hospital, serotonin-norepinephrine reuptake inhibitor duloxetine significant improve depression, vasomotor symptoms, sleep, anxiety, and pain after 8 weeks(5).

Dr. Joffe H and the research team at the joint study lead Harvard Medical School, low-dose oral estradiol and venlafaxine(serotonin-norepinephrine reuptake inhibitor  are effective treatments for VMS in women during midlife(6).

Another selective serotonin reuptake inhibitor, escitalopram, also alleviated the frequency, severity, and bother of menopausal hot flashes in the study of 205 women (95 African American; 102 white; 8 other) between July 2009 and June 2010.(7).
Green tea contains more amount of antioxidants than any drinks or food with the same volume, and is the leaves of Camellia sinensis, undergone minimal oxidation during processing, originated from China. According to the joint study led by the Seton Hall University, theaflavin digallate isolated from green expressed anti viral activity against inflammation in stable at vaginal pH, and inhibited HSV-1 viral particles(9).
Its epigallocatechin gallate (EGCg) also enhanced the antifungal effect of amphotericin B or fluconazole against antimycotic-susceptible and -resistant C. albicans(10).

The effectiveness of Green Tea, Sweet Potato and Flax Seed may serve as cornerstones of pharmaceutical target for further studies in production of a potential medication for for Reduced Risk of Consequences of  Atrophic Vaginitis  with little or no adverse effects.

Intake of Smoothie of Pineapple, Banana and Asian ginseng (Panax ginseng) Herbal Tea may Reduced Risk and treatment of Atrophic Vaginitis due to aging
Life style and dietary patter change are recommended.

All Forms of Arthritis are Curable

Ovarian Cysts And PCOS Elimination



References
(1) Open, non-controlled clinical studies to assess the efficacy and safety of a medical device in form of gel topically and intravaginally used in postmenopausal women with genital atrophy by Morali G1, Polatti F, Metelitsa EN, Mascarucci P, Magnani P, Marrè GB.(PubMed)
(2) Phytoestrogen-Rich Dietary Supplements in Anti-Atherosclerotic Therapy in Postmenopausal Women by Sobenin IA1, Myasoedova VA, Orekhov AN.(PubMed)
(3) [Phytoestrogens--whether can they be an alternative to hormone replacement therapy for women during menopause period?].[Article in Polish] by Dittfeld A, Koszowska A, Brończyk AP, Nowak J, Gwizdek K, Zubelewicz-Szkodzińska B.(PubMed)
(4) Methods for the design of vasomotor symptom trials: the menopausal strategies: finding lasting answers to symptoms and health network by Newton KM1, Carpenter JS, Guthrie KA, Anderson GL, Caan B, Cohen LS, Ensrud KE, Freeman EW, Joffe H, Sternfeld B, Reed SD,Sherman S, Sammel MD, Kroenke K, Larson JC, Lacroix AZ.(PubMed)
(5) Treatment of depression and menopause-related symptoms with the serotonin-norepinephrine reuptake inhibitor duloxetine. by Joffe H1, Soares CN, Petrillo LF, Viguera AC, Somley BL, Koch JK, Cohen LS.(PubMed)
(6) Low-dose estradiol and the serotonin-norepinephrine reuptake inhibitor venlafaxine forvasomotor symptoms: a randomized clinical trial by Joffe H1, Guthrie KA2, LaCroix AZ2, Reed SD3, Ensrud KE4, Manson JE5, Newton KM6, Freeman EW7, Anderson GL2, Larson JC2, Hunt J2,Shifren J8, Rexrode KM5, Caan B9, Sternfeld B9, Carpenter JS10, Cohen L8(PubMed)
(7) Efficacy of escitalopram for hot flashes in healthy menopausal women: a randomized controlled trial. by Freeman EW1, Guthrie KA, Caan B, Sternfeld B, Cohen LS, Joffe H, Carpenter JS, Anderson GL, Larson JC, Ensrud KE, Reed SD, Newton KM, Sherman S, Sammel MD, LaCroix AZ.(PubMed)
(8) The effect of vaginally administered genistein in comparison with hyaluronic acid on atrophic epithelium in postmenopause by Le Donne M1, Caruso C, Mancuso A, Costa G, Iemmo R, Pizzimenti G, Cavallari V.(PubMed)
(9) Antiviral activity of theaflavin digallate against herpes simplex virus type 1 by de Oliveira A1, Prince D1, Lo CY2, Lee LH3, Chu TC4.(PubMed)
(10) Multiple effects of green tea catechin on the antifungal activity of antimycotics against Candida albicans by Hirasawa M1, Takada K.(PubMed)

Most Common Diseases of elder: Respiratory Pleural disease: Pneumothorax - The Antioxidants

Kyle J. Norton(Scholar and Master of Nutrients, all right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

                                          Respiratory Disease

Respiratory Disease is defined as medical conditions, affecting the breathing organ and tissues including Inflammatory lung disease, Obstructive lung diseases, Restrictive lung diseases, Respiratory tract infections, trachea, bronchi, bronchioles, alveoli, the nerves and muscles breathing , etc,.

                   Pleural disease: Pneumothorax

The pleura is a thin tissue covered by a layer of cells (mesothelial cells) that surrounds the lungs and lines the inside of the chest wall.
Pneumothorax is a condition of collection of air within the pleural cavity, from either the outside or from the lung of which affect the lung breathing.

The Antioxidants 

According to the study by the Trakya University, patients with Pneumothorax are associated with oxidate stress as erythrocyte superoxide dismutase activity was found to be significantly lower and the plasma malondialdehyde levels were significantly high in patients with primary spontaneous pneumothorax (PSP)(47).
Other study indicated that the clinical manifestations in all forms of this pathology had poor symptoms. Complex therapy proved to be highly effective. It included use of corticosteroids, antioxidants and immunomodulators; massive exudative pleurisy was managed by pleural puncture and removal of exudate, .in the study of a total of 2775 respiratory sarcoidosis patients who were examined over the last ten years 278 (10%) had pleural affections: thickening of interlobular pleura and pleural deposits (98.2%), exudative pleurisy (1.1%) and spontaneous pneumothorax (0.7%)(48).
2. N-acetyl-L-cysteine (NAC)
Reactive free oxygen radicals are known to play an important role in the pathogenesis of various lung diseases. According to the study by the University Hospital Bergmannsheil, Ruhr-University, in the study to investigate of N-acetyl-L-cysteine (NAC) and ambroxol, its SH group, NAC scavenges H2O2 (hydrogen peroxide), .OH (hydroxol radical), and HOCl (hypochlorous acid). Furthermore, NAC can easily be deacetylated to cysteine, an important precursor of cellular glutathione synthesis, and thus stimulate the cellular glutathione system. This is most evident in pulmonary diseases characterized by low glutathione levels and high oxidant production by inflammatory cells (e.g. in IPF and ARDS). NAC is an effective drug in the treatment of paracetamol intoxication and may even be protective against side-effects of mutagenic agents. In addition NAC reduces cellular production of pro-inflammatory mediators (e.g. TNF-alpha, IL-1). Also, ambroxol [trans-4-(2-amino-3,5-dibromobenzylamino)-cyclohexane hydrochloride] scavenges oxidants (e.g. .OH, HOCl)(49)

Sources
(47) http://www.ncbi.nlm.nih.gov/pubmed/15223614
(48) http://www.ncbi.nlm.nih.gov/pubmed/1488432
(49) http://www.ncbi.nlm.nih.gov/pubmed/9659525

Tuesday, March 15, 2016

The Workable Green Tea, Orange and Turmeric for Prevention and Treatment of Cirrhosis

Kyle J. Norton(Scholar, Master of Nutrients), all right reserved.
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

The smoothie for prevention and treatment of Cirrhosis
Yield: 2 servings (about 8 ounces each)
1 1/2 cups orange
1 tsp curcumin
1 cup green tea drink (Make from 4 grams of green tea and a cup of hot water lipped for 5 minutes, and let cool to room temperature)

1. Place all ingredients in a blender and puree about 1 minute
2. Blend on high speed about 1 minute or until the mixture is thick and the ice is well crushed.
3. Serve immediately

The finding of a natural source for treatment of Cirrhosis has been running into many obstacles, many ingredients showed initially with promising result in animal studies have not produced same potentials in large sample size and mutli centers human trials.

Cirrhosis is defined as a condition of irreversible scarring liver as a result of liver tissue by fibrosis due to final phase of chronic liver diseases of that can lead to poor function of the liver and liver failure.
Recent studies back by well known institutions proposed, Green Tea, Vitamin E, and  Resveratrol and Silymarin isolated from Tomato, Sweet Potato and Peanut respectively may be the next generation of natural ingredients for prevention and treatment of Cirrhosis.

Green tea has been a precious drink in traditional Chinese culture and used exceptional in socialization for more than 4000 thousand years. Due to its commercial values and health effects, green tea now has been cultivated all over the world in suitable climate. According to the Fudan University, intake of green tea extracts (GTE) can protect against CCl(4)-induced liver damage and cirrhosis in animal model(1).
Dr.Yin X and colleagues at the joint study lead by the Zhujiang Hospital of Southern Medical University, regular intake of green tea intake is associated to reduce risk of liver disease, including liver cirrhosis(2).
In the study of the effect of Green Tea Extract (GTE) encapsulated into Chitosan Nanoparticles (CS-NPs), researchers showed that the combination are effective in removing all the extracellular collagen caused by CCl4 in the hepatic fibrosis rat liver(3).

Hesperetin, found abundantly in Citrus fruits, including orange also expressed hepatoprotective effect
against liver fibrosis through targeting the Wnt/β-catenin signaling pathway in diseases contribution(4). According to the Renmin Hospital of Wuhan University, orange flavonoid hesperetin also protected against cardiac remodelling induced by pressure overload via inhibiting cardiac hypertrophy, fibrosis, oxidative stress and myocytes apoptosis(5).

Curcumin, a spice derived from Tuermic not only attenuated hepatic damage in several animal models of liver injury but also inhibited the development liver cirrhosis through its anti-inflammatory activities(6).

According to the Sección Externa de Farmacología, Cinvestav-IPN, Curcumin was effective in preventing and reversing cirrhosis, probably through reducing TGF-beta expression in regulation of proliferation, cellular differentiation, and other functions in most cells(7).
Furthermore, curcumin also exerted liver protective effect against liver damage induced chronic liver diseases, including cirrhosis(8).

Taking altogether, the combination of Orange, Turmeric and Green Tea may process the activities in reduced risk and treatment of patient with Cirrhosis

People who are at increased risk of Cirrhosis due to family history, .... should drink 1 serving daily and people with Cirrhosis should drink as much as they can, depending to digestive toleration.
Life style and diet pattern changed are recommended

References
(1) [Green tea extracts protected against carbon tetrachloride-induced chronic liver damage and cirrhosis].[Article in Chinese] by Xiao J1, Lu R, Shen X, Wu M.(PubMed)
(2) The effect of green tea intake on risk of liver disease: a meta analysis by Yin X1, Yang J2, Li T3, Song L4, Han T5, Yang M1, Liao H1, He J1, Zhong X1.(PubMed)
(3) Effect of Green Tea Extract Encapsulated Into Chitosan Nanoparticles on Hepatic Fibrosis Collagen Fibers Assessed by Atomic Force Microscopy in Rat Hepatic Fibrosis Model by Safer AM, Hanafy NA, Bharali DJ, Cui H, Mousa SA.(PubMed)
(4) Hesperetin derivative-7 inhibits PDGF-BB-induced hepatic stellate cell activation and proliferation by targeting Wnt/β-catenin pathway by Lin X1, Kong LN1, Huang C1, Ma TT1, Meng XM1, He Y1, Wang QQ1, Li J2.(PubMed)
(5) Hesperetin protects against cardiac remodelling induced by pressure overload in mice. by Deng W1, Jiang D, Fang Y, Zhou H, Cheng Z, Lin Y, Zhang R, Zhang J, Pu P, Liu Y, Bian Z, Tang Q.(PubMed)
(6) Prevention of liver cirrhosis in rats by curcumin. by Bruck R1, Ashkenazi M, Weiss S, Goldiner I, Shapiro H, Aeed H, Genina O, Helpern Z, Pines M.(PubMed)