Tuesday, April 5, 2016

Most Common Diseases of elder: Respiratory Pleural disease: Pleural Plaques - Treatment In traditional Chinese medicine perspective

Kyle J. Norton(Scholar and Master of Nutrients, all right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

                                          Respiratory Disease

Respiratory Disease is defined as medical conditions, affecting the breathing organ and tissues including Inflammatory lung disease, Obstructive lung diseases, Restrictive lung diseases, Respiratory tract infections, trachea, bronchi, bronchioles, alveoli, the nerves and muscles breathing, etc,.

                   Pleural disease: Pleural Plaques

The pleura is a thin tissue covered by a layer of cells (mesothelial cells) that surrounds the lungs and lines the inside of the chest wall.
Pleural plaques is a medical condition as a result of exposure to asbestos that lead to accumulated plagues within the pleural cavity(a). Many diseases such as pneumonia, breast cancer, and heart failure can affect the pleural space.,therefore, it is often a secondary effect of another disease process.

The Treatment

In traditional Chinese medicine perspective(47)
Bai He Gu Jin Pian, one of many Chinese herb formula used by TCM to nourish lung Yin energy, moisten the lungs, transform phlegm, and stop cough may have a potential in treating lung diseases, including
1. Bai He
Bai He, is also known as Bulbus Lilii. The Sweet, slightly bitter, slightly cold herb has been used in TCM to treat Chronic cough, blood-streaked sputum, difficult to solve chronic low grade fever, insomnia with abundance of dreams, inability to concentrate, restlessness, irritability, etc., by enhancing the function of heart and lung function.
2. Di Huang
a. Sheng di huang
The bitter, sweet, bitter cold herb has been used in TCM as diuretic agent and to enhance heart function (small doses constrict the blood vessels and large doses dilate the blood vessel), decrease blood sugar, etc., as it clears Heat and cools the Blood, nourishes Yin, generates Fluids, cools the Upward-Blazing of Heart Fire, etc., by promoting the functions of heart, kidney, and liver channels.
b. Shu di huang
The bitter, sweet, bitter and warm herb has been used in as diuretic agent and to enhance heart function (small doses constrict the blood vessels and large doses dilate the blood vessel), decrease blood sugar, etc., as it clears Heat and cools the Blood (Sheng) as it nourishes Yin and Blood, tonifies the Essence, strengthens the Marrow, etc., by enhancing the functions of heart, kidney, and liver channels.
3. Mai Men Dong
Mai Dong or Mai Men Dong is also known as Ophiopogon tuber. The sweet and slightly bitter and cold herb has been used in TCM as anti-arrhythmia, Anti shock, anti bacterial agent and improve contraction of heart muscles, and improves toleration of lack of oxygen, protect heart muscle, enhance immune system, lower blood sugar, etc., as it moistens the Lung and Lung-Yin, benefits the Stomach, promotes generation of Body Fluids, clears the Heart, calms restlessness and anxiety, etc., by enhancing the functions of hear, lung and stomach channels.
4. Xuan Shen
Xuan Shen is also known as Figwort Root. The salty, sweet, bitter and cold herb has been used in TCM as anti bacterial, anti inflammatory, sedative, anti-pyretic agent and to lower blood pressure, blood sugar, etc., as it clears Heat, expels toxins, nourishes Yin, etc. by enhancing the functions of kidney, lung and stomach channels.
5. Bei Mu
Bei Mu is also known as Fritillary Bulb. The sweet, bitter and cold herb has been used in TCM as antibiotic and to raise blood pressure, stop cough, , increased blood sugar,etc. as it transforms Phlegm, calms cough; clears Heat, dissolves nodules, etc. by enhancing the functions of heart and lung channels.
6. Jie Geng
Jie geng is also known as Platycodon root. The bitter, acrid neutral herb has been used in TCM to get rid of phlegm, inhibit cough, treat bronchitis and sore throat, etc., by enhancing the function of lung channel.
7. Gan Cao
Gan Cao is also known as Licorice root. The sweet and neutral herb has been used in TCM as anti allergy, anti inflammation, anti ulcer, anti convulsion and to treat stomach weakness, tired and lack of strength, palpitation and short of breath, cough with abundance of phlegm, stomach and solar plexus pain, etc., as it tonifies the Spleen, benefits the Qi, moistens the Lungs, calms cough, deaf or acute pain, by enhancing all 12 channels.
8. Dang Gui
Dang Qui is also known as Angelica Root. The sweet, bitter, acrid and warm herb has been used in TCM to regulate the menses, lower lipids, reduce platelet coagulation and swelling, expel pus, relieve pain, etc/, as it tonifies and moves Blood, calms pain, moistens the Intestines, etc., by enhancing the function of heart, liver and spleen channels.
9. Bai Shao
Bai Shao also known as White Paeony Root, the bitter sour and cool herb has been used in TCM as anti-spastic, anticonvulsant, analgesic, sedative, antipyretic, anti-inflammatory, antibiotic agent and to owers blood pressure, dilates peripheral blood vessels etc., as it nourishes Blood and liver, preserves the Yin, clams pain;, etc., by promoting the function of liver and spleen channels.

All Forms of Arthritis are Curable
You Can Eliminate Osteoarthritis
By addressing the Underlying Causes through Clinical Trials and Studies

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Super foods Library, Eat Yourself Healthy With The Best of the Best Nature Has to Offer

Monday, April 4, 2016

Most Common Disease of 50Plus: The Clinical trials and Studies of Musculo-Skeletal disorders(MSDs) - Osteoarthritis: The Do and do not’s list

Kyle J. Norton (Scholar)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

Musculoskeletal disorders (MSDs) are medical condition mostly caused by work related occupations and working environment, affecting patients’ muscles, joints, tendons, ligaments and nerves and developing over time. A community sample of 73 females and 32 males aged 85 and over underwent a standardised examination at home. Musculoskeletal pain was reported by 57% of those interviewed. A major restriction of joint movement range was frequent in the shoulder but uncommon in other joints(1).

Types of Musculo-Skeletal disorders in elder(2)

1. Osteoarthritis
2. Gout
3. Rheumatoid Arthritis
4. Polymalagia Arthritis
5. Cervical myleopathy and spinal canal stenosis
6. Osteoporosis
7. Low back pain
8. Fibromyalgia          



                                                      Osteoarthritis


Osteoarthritis (OA), a form of arthritis, is defined as a condition of as a result of aging causes of wear and tear on a joint, affecting over 25 million people in the United States in alone. University of Porto Medical School indicated that one must understand the differences in prevalence and incidence estimates of osteoarthritis (OA), according to case definition, in knee, hip and hand joints(3).
The characteristics of osteoarthritis are aching pain(5), stiffness(6), or difficulty of moving the joint or joints(7). The pain usually gets worse in change of weather, at night and in the advanced diseases, the pain can occur even at rest(8). Today management of osteoarthritis (OA) focuses on pain relief and improved physical function through pharmacological, non pharmacological, and surgical treatments(4).

The Prevention and management The Do and do not’s list

1. Prevention recurrent injure to damage menisci
The meniscus is an important tissue because if its function in shock absorption and load distribution in the healthy knee joint(111). A meniscal tear can lead to knee osteoarthritis (OA), but knee OA can also lead to a spontaneous breakdown of meniscal tear and damage to meniscal structure(112). Meniscus damage or recurrent injure might be considered as a signifying feature of incipient OA in middle-aged and elderly people(113).

2. Take precaution if your occupation is at increased risk of osteoarthritis
Osteoarthritis (OA) is one of the most important diseases as it frequently affects the active age group of the population contributed to loss of working hours and of disability(114)(115)(117). Compressive, torsional, pulling and angular movements common in certain occupations or sports may result in injuries of soft tissue, thus increasing the development of OA(116).

3. Muscle strengthening and aerobic exercises
Enhanced muscle strengthening with neuromuscular electrical stimulation(118), aerobic exercises(119) and exercice(220) are effective in reducing pain and improving physical function in patients with mild to moderate OA of the knee(220).

4. Maintain a healthy weight(117)
Increased BMI and obesity are associated with more severe cartilage degeneration(121)(123) as assessed by both morphological and quantitative MRI measurements(122).

5. Avoid dehydration
Dehydration has shown to reduce the mobility of collagen amino acid residues and carbon sugar ring structures in glycosaminoglycans, according to University of Michigan(124) of that may effect the functions of cartilage and induce the risk of OA(125), but dehydration effects are reversible, through the restoration of molecular structure and mobility(124).

6. Avoid intake of inflammatory foods
Loading up on junk foods and fast foods contains high amount of trans fat of that increases the risk of inflammation(126) exhibit pro inflammatory effects(127) causes of osteoarthritis (OA)(128). Red meat, eggs, and wheat products all contain high amount of arachidonic acid, too much arachidonic acid may be worsen the inflammation process(129), etc.

7. Eat your fruits and vegetables
Fruits and vegetables containning high amount of nutrients and antioxidant(130), can enhance immune defense system(131)within the joint through direct infleuences of transferrin performance for reduction of inflammation(131)(132) as well as suppressing free radicals and the chain of free radicals reaction cause of elevating the swelling and promoting degeneration(133)(134).

8. Replace regular beverage with green tea
Epigallocatechin-3-gallate, a green tea polyphenol(135)(136), was found to be effective in reducing inflammatory cytokines induced inflammatory diseases(137)(138).

9. Etc.


Arthritis Is Curable
You Can Eliminate Osteoarthritis
By addressing the Underlying Causes through Clinical Trials and Studies


Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Super foods Library, Eat Yourself Healthy With The Best of the Best Nature Has to Offer


References
(1) Prevalence of rheumatic symptoms, rheumatoid arthritis, ankylosing spondylitis, and gout in Shanghai, China: a COPCORD study by Dai SM1, Han XH, Zhao DB, Shi YQ, Liu Y, Meng JM.(PubMed)
(2) Musculoskeletal Disorders in the Elderly by Ramon Gheno, Juan M. Cepparo, Cristina E. Rosca,1 and Anne Cotten(PMC)
(3) The effect of osteoarthritis definition on prevalence and incidence estimates: a systematic review by Pereira D1, Peleteiro B, Araújo J, Branco J, Santos RA, Ramos E.(PubMed)
(4) Effect of therapeutic aquatic exercise on symptoms and function associated with lower limb osteoarthritis: systematic review with meta-analysis by Waller B1, Ogonowska-Slodownik A2, Vitor M3, Lambeck J4, Daly D5, Kujala UM6, Heinonen A7.(PubMed)
(5) Effects of therapeutic ultrasound on pain, physical functions and safety outcomes in patients with kneeosteoarthritis: A systematic review and meta-analysis by Zhang C1, Xie Y2, Luo X3, Ji Q3, Lu C3, He C4, Wang P3.(PubMed)
(6) Oral intake of purple passion fruit peel extract reduces pain and stiffness and improves physical function in adult patients with knee osteoarthritis by Farid R1, Rezaieyazdi Z, Mirfeizi Z, Hatef MR, Mirheidari M, Mansouri H, Esmaelli H, Bentley G, Lu Y, Foo Y, Watson RR.(PubMed)
(7) Functional ability, mobility, and pain before and after knee replacement in patients aged 75 and older: a cross-sectional study by Limnell K1, Jämsen E, Huhtala H, Jäntti P, Puolakka T, Jylhä M.(PubMed)
(8) The symptoms of OA and the genesis of pain by David J. Hunter, MBBS PhD,1,2 Jason J. McDougall, BSc PhD,3 and Francis J. Keefe4(PubMed)
(111) The meniscus in knee osteoarthritis by Englund M1, Guermazi A, Lohmander LS.(PubMed)
(112) The role of the meniscus in knee osteoarthritis: a cause or consequence? by Englund M1, Guermazi A, Lohmander SL.(PubMed)
(113) Meniscus pathology, osteoarthritis and the treatment controversy by Englund M1, Roemer FW, Hayashi D, Crema MD, Guermazi A.(PubMed)
(114) Productivity loss due to presenteeism among patients with arthritis: estimates from 4 instruments by Zhang W1, Gignac MA, Beaton D, Tang K, Anis AH; Canadian Arthritis Network Work Productivity Group(PubMed)
(115) Occupational lifting is associated with hip osteoarthritis: a Japanese case-control study. by Yoshimura N1, Sasaki S, Iwasaki K, Danjoh S, Kinoshita H, Yasuda T, Tamaki T, Hashimoto T, Kellingray S, Croft P, Coggon D, Cooper C.(PubMed)(116) Occupation and osteoarthritis by Genti G.(PubMed)
(117) Risk factors for knee osteoarthritis in Japanese women: heavy weight, previous joint injuries, and occupational activities by Yoshimura N1, Nishioka S, Kinoshita H, Hori N, Nishioka T, Ryujin M, Mantani Y, Miyake M, Coggon D, Cooper C.(PubMed)
(118) Neuromuscular electrical stimulation for muscle strengthening in elderly with knee osteoarthritis - a systematic review by de Oliveira Melo M1, Aragão FA, Vaz MA.(PubMed)
(119) Effectiveness of exercise for osteoarthritis of the knee: A review of the literature. by Iwamoto J1, Sato Y, Takeda T, Matsumoto H.(PubMed)
(120) Effectiveness of exercise for osteoarthritis of the knee: A review of the literature by Iwamoto J1, Sato Y, Takeda T, Matsumoto H.(PubMed)
(121) Articular Cartilage Degeneration: Etiologic Association With Obesity by Deryk G. Jones, MD(PubMed)
(122) Correlation of magnetic resonance imaging-based knee cartilage T2 measurements and focal knee lesions with body mass index: thirty-six-month followup data from a longitudinal, observational multicenter study by Baum T1, Joseph GB, Nardo L, Virayavanich W, Arulanandan A, Alizai H, Carballido-Gamio J, Nevitt MC, Lynch J, McCulloch CE, Link TM.(PubMed)
(123) The evolving role of obesity in knee osteoarthritis by MaryFran R. Sowers and Carrie A. Karvonen-Gutierrez(PMC)
(124) Solid-state NMR spectroscopy provides atomic-level insights into the dehydration of cartilage by Xu J1, Zhu P, Morris MD, Ramamoorthy A.(PubMed)
(125) Geriatric Rehabilitation Manual By Timothy L. Kauffman
(126) Dietary intake of trans fatty acids and systemic inflammation in women by Mozaffarian D1, Pischon T, Hankinson SE, Rifai N, Joshipura K, Willett WC, Rimm EB.(PubMed)
(127) Health effects of trans-fatty acids: experimental and observational evidence by Mozaffarian D1, Aro A, Willett WC.(PubMed)
(128) Metabolic triggered inflammation in osteoarthritis by Wang X1, Hunter D2, Xu J3, Ding C4.(PubMed)
(129) Arachidonic acid metabolism: role in inflammation by Samuelsson B1.(PubMed)
(130) Antagonizing arachidonic acid-derived eicosanoids reduces inflammatory Th17 and Th1 cell-mediatedinflammation and colitis severity. by Monk JM1, Turk HF1, Fan YY1, Callaway E1, Weeks B2, Yang P3, McMurray DN4, Chapkin RS5.(PubMed)
(130) Effect of fruit and vegetable antioxidants on total antioxidant capacity of blood plasma by Harasym J1, Oledzki R2.(PubMed)
(131) Dietary antioxidants: immunity and host defense by Puertollano MA1, Puertollano E, de Cienfuegos GÁ, de Pablo MA.(PubMed)
(132) Cellular immunity in osteoarthritis: novel concepts for an old disease by Liossis SN1, Tsokos GC.(PubMed)
(133) Free Radicals, Antioxidants in Disease and Health by Lien Ai Pham-Huy,1 Hua He,2 and Chuong Pham-Huy3(PMC)
(134) Studies on free radicals, antioxidants, and co-factors by Khalid Rahman(PMC)
(135) New insights into the mechanisms of polyphenols beyond antioxidant properties; lessons from the green tea polyphenol, epigallocatechin 3-gallate by Hae-Suk Kim,a Michael J. Quon,c and Jeong-a Kima,b(PMC)
(136) Green tea catechin, epigallocatechin-3-gallate (EGCG): mechanisms, perspectives and clinical applications by Singh BN1, Shankar S, Srivastava RK.(PubMed)
(137) Dietary polyphenols and mechanisms of osteoarthritis by Shen CL1, Smith BJ, Lo DF, Chyu MC, Dunn DM, Chen CH, Kwun IS.(PubMed)
(138) Green tea: a new option for the prevention or control of osteoarthritis by Katiyar SK, Raman C.(PubMed)

The tasty Smoothie of Green Tea, Pomegranate and Peanut for Prevention and Treatment of Acute fatty liver of pregnancy (AFLP)

Kyle J. Norton(Scholar, Master of Nutrients), all right reserved.
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

The smoothie for prevention and treatment of Acute fatty liver of pregnancy (AFLP)
Yield: 2 servings (about 8 ounces each)
3/4 cup pomegranate juice
1/4 cup peanut
1 cup green tea drink (Make from 4 grams(2 tea bags) of green tea, and a cup of hot water lipped for 5 minutes, and set aside for cooling to room temperature)

1. Place all ingredients in a blender and puree about 1 minute
2. Blend on high speed about 1 minute or until the mixture is thick and the ice is well crushed.
3. Serve immediately

The finding of a natural source for treatment of  Acute fatty liver of pregnancy (AFLP) has been running into many obstacles, many ingredients showed initially with promising result in animal studies have not produced same potentials in large sample size and mutli centers human trials.

Acute fatty liver of pregnancy occurs in third trimester or early postpartum period caused by a disordered metabolism of fatty acids by mitochondria in the fetus. It is a rare, potentional fatal disease(1). According to the joint study lead by the University of Texas Medical Branch Galveston, Acute fatty liver of pregnancy may induce the early vitamin K deficiency bleeding in a newborn with risk of morbidity and mortality(2).th
The increased oxidative stress and reduced antioxidants status also were found in women with acute fatty liver of pregnancy (AFLP)(3).

According to the guideline provided by the Patrick Cowie & Ian G Johnston Department of Anaesthetics, Raigmore Hospital,treatment of acute fatty liver of pregnancy is usually supportive and similar to that of other causes of hepatic dysfunction with practice led to improved outcomes for both mother and child.

Recent studies back by well known institutions proposed, Silymarin, Pomegranates juice, and Green Tea  may be the next generation of natural ingredients for prevention and treatment of Acute fatty liver of pregnancy (AFLP)

Silymarin, a phytochemical in the class of phenolic acids, found abundantly in peanut is associated to ameliorated the impairment of hepatic function, through its antioxidant, anti-inflammatory, antifibrotic and anti-apoptotic effects(4).
Dr. Surai PF, professors at Eastern European University said, "Silymarin (SM), an extract from the Silybum marianum (milk thistle) plant containing various flavonolignans (with silybin being the major one), has received a tremendous amount of attention over the last decade as a herbal remedy for liver treatment. In many cases, the antioxidant properties of SM are considered to be responsible for its protective actions"(5).
The Nanjing University School of Medicine study insisted, silymarin treatment reduced the effect of pro inflammatory cytokines such as IL-1β, TNF-α levels induced oxidative stress, and activated immunity in modulation of cytokine and nitric oxide production,...(6).

Pomegranates is a fruit-bearing small tree, genus Punica, belonging to family Lythraceae, native to Iran but has been cultivated in Asian since ancient time. According to the Alexandria University, pomegranate juice (PJ) expressed liver dysfunction protective efects on hepatic antioxidant enzyme activities, lipid peroxidation, DNA fragmentation (DNAF), and caspase-3 activity(7).
Punicalagin (PU), the major ellagitannins found in the pomegranate (Punica granatum) significantly inhibited high fat diet-induced hyperlipidemia and hepatic lipid deposition due to liver mitochondrial dysfunction, by ameliorated the increased expression of pro-inflammatory cytokines(8).

Green tea has been a precious drink in traditional Chinese culture and used exceptional in socialization for more than 4000 thousand years. Because of their health benefits, they have been cultivated for commercial purposes all over the world. According to the University of Sfax, oral administration of green tea, along with cadmium significantly (p < 0.05) improves cadmium-induced liver dysfunction and stress oxidant in rats' liver(9).Dr. Cai X and colleagues at the joint study lea by the Hyogo College of Medicine, suggested, Pu-erh tea, made from the leaves of Camellia sinensis ameliorates hepatic lipid metabolism, inflammation, and insulin resistance in mice with high fat diet(HFD)-induced NASH, presumably by modulating hepatic IL-6/STAT3(the proinflammatory) signaling(10).

Taking altogether, the combination of Green Tea and Orange may process the activities in prevention and treatment of Gallstones

Women who are at higher risk of  acute fatty liver of pregnancy (AFLP), due to family history, dietary pattern, obesity,... .... should drink 1 serving daily and women with acute fatty liver of pregnancy (AFLP) should drink as much as they can, depending to digestive toleration.
Life style and diet pattern changed are recommended



References
(1) [Acute fatty liver of pregnancy (AFLP)--case report].[Article in Czech] by Kacerovský M1, Hossner P.(PubMe)
(2) Early Vitamin K Deficiency Bleeding in a Neonate Associated with Maternal Acute Fatty Liver of Pregnancy by Arya S1, Richardson CJ2, Jain S2, Swischuck LE3.(PubMed)
(3) Liver injury in acute fatty liver of pregnancy: possible link to placental mitochondrial dysfunction and oxidative stress. by Natarajan SK1, Thangaraj KR, Eapen CE, Ramachandran A, Mukhopadhya A, Mathai M, Seshadri L, Peedikayil A, Ramakrishna B,Balasubramanian KA.(PubMed)
(4) Antioxidant, anti-inflammatory and hepatoprotective effects of silymarin on hepatic dysfunction induced by sodium nitrite by Sherif IO1, Al-Gayyar MM.(PubMed)
(5) Silymarin as a Natural Antioxidant: An Overview of the Current Evidence and Perspectives. by Surai PF1,2,3,4.(PubMed)
(6) Silymarin alleviates hepatic oxidative stress and protects against metabolic disorders in high-fat diet-fed mice by Feng B1, Meng R1, Huang B1, Shen S1, Bi Y1, Zhu D1.(PubMed)
(7)Effect of Punica granatum (pomegranate) juice extract on healthy liver and hepatotoxicity induced by diethylnitrosamine and phenobarbital in male rats by Shaban NZ1, El-Kersh MA, Bader-Eldin MM, Kato SA, Hamoda AF.(PubMed)
(8)Mitochondrial dysfunction in obesity-associated nonalcoholic fatty liver disease: the protective effects of pomegranate with its active component punicalagin by Zou X1, Yan C, Shi Y, Cao K, Xu J, Wang X, Chen C, Luo C, Li Y, Gao J, Pang W, Zhao J, Zhao F, Li H, Zheng A, Sun W, Long J, Szeto IM, Zhao Y, Dong Z,Zhang P, Wang J, Lu W, Zhang Y, Liu J, Feng Z.(PubMed)
(9) Positive effects of green tea on hepatic dysfunction, lipid peroxidation and antioxidant defence depletion induced by cadmium by Hamden K1, Carreau S, Marki FA, Masmoudi H, El Feki A.(PubMed)
(10) Pu-erh tea extract ameliorates high-fat diet-induced nonalcoholic steatohepatitis and insulin resistance by modulating hepatic IL-6/STAT3 signaling in mice by Cai X1,2,3, Fang C2,4, Hayashi S2,3, Hao S5, Zhao M6, Tsutsui H2,3, Nishiguchi S7, Sheng J8.(PubMed)

Most Common Diseases of elder: Respiratory Pleural disease: Pleural Plaques - Treatment in Conventional and Alternative Medicine

Kyle J. Norton(Scholar and Master of Nutrients, all right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

                                          Respiratory Disease

Respiratory Disease is defined as medical conditions, affecting the breathing organ and tissues including Inflammatory lung disease, Obstructive lung diseases, Restrictive lung diseases, Respiratory tract infections, trachea, bronchi, bronchioles, alveoli, the nerves and muscles breathing, etc,.

                   Pleural disease: Pleural Plaques

The pleura is a thin tissue covered by a layer of cells (mesothelial cells) that surrounds the lungs and lines the inside of the chest wall.
Pleural plaques is a medical condition as a result of exposure to asbestos that lead to accumulated plagues within the pleural cavity(a). Many diseases such as pneumonia, breast cancer, and heart failure can affect the pleural space.,therefore, it is often a secondary effect of another disease process.

The Treatment

In conventional medicine perspective
There is no treatment even if you are diagnosed with pleural plague but no symptoms as you can live with them without having any long-term problems with your health. According to the British Lung foundation, If you have pleural plaques, it does not mean that:you will go on to get a more serious disease or you have a more serious disease at the moment; or you are likely to get a serious disease in the future(38).
But you smokes and have exposed to asbestos, you are advised to quit, as smoking are associated with increased risk to develop pleural and other diseases(39).
 
 In Alternative medicine perspective
The following herbs which have been proving to enhance lung function and treat many types of lung diseases may be potential in treating pleural plague
1. Coltsfoot
Coltsfoot (Tussilago farfara) is a perennial herbaceous plant, genus Tussilago, belonging to the family Asteraceae, native to Europe and Asia. The herb has been used over thousands of year to treat asthma, various coughs, bronchial congestion, respiratory disorders, headaches and obstruction in the nasal passage, etc.
a. Antioxidant activity
In the investigation of antioxidant capacities of 56 selected Chinese medicinal plants were evaluated using the Trolox equivalent antioxidant capacity (TEAC) and ferric reducing antioxidant power (FRAP) assays found that that the antioxidants in Dioscorea bulbifera, Eriobotrya japonica, Tussilago farfara and Ephedra sinica possess free radical scavenging activity and oxidant reducing power, and the high positive correlation between antioxidant capacities and total phenolic content, according to the study of “Total phenolic contents and antioxidant capacities of selected chinese medicinal plants” by Song FL, Gan RY, Zhang Y, Xiao Q, Kuang L, Li HB.(40)
b. Anti-inflammatory effect
In the evaluation of Tussilagone (TSL), isolated from the flower of buds of Tussilago farfara (Compositae), is a sesquiterpenoid that is known to exert a variety of pharmacological activities. found that TSL exerts anti-inflammatory activities in murine macrophages by inducing heme oxygenase-1 (HO-1) expression, according to the study of “The anti-inflammatory effect of tussilagone, from Tussilago farfara, is mediated by the induction of heme oxygenase-1 in murine macrophages” by Hwangbo C, Lee HS, Park J, Choe J, Lee JH.(41)
c. Immune system
In the observation of polysaccharides from coltsfoot, sweet flag, clover, Artemisia, marigold, and elecampane and their effects in IgE- and G1 dependent diseases found that induction of anaphylactic shock. In addition, injection of these substances reduced serum concentrations of IgE and IgG1. These substances can be regarded as promising agents for the treatment of IgE-dependent diseases (atopic dermatitis, asthma, atopic rhinitis, urticaria, food allergies, etc.), according to the study of “Effects of plant water-soluble polysaccharides on the production of immunoglobulins E and G1 by lymphocytes of mice sensitized with ovalbumin” by Danilets MG, Belska NV, Bel’sky YP, Uchasova EG, Trophimova ES, Ligatcheva AA, Guriev AM, Belousov MV, Ahmedganov RR, Usubov MS, Agaphonov VI.(42).

2. Mullein
Mullein is hairy biennial plant, genus Verbascum, belonging to Scrophulariaceae, native to Europe, northern Africa and Asia. The herb has been used in traditional medicine over thousands of year as analgesic, antihistaminic, anti-inflammatory, anticancer, antioxidant, antiviral, bacteristat, cardio-depressant, estrogenic, sedative medicine and to treat cough, whooping cough, tuberculosis, bronchitis, hoarseness, pneumonia, earaches, colds, chills, flu, etc.
In the evaluation of Verbascum thapsus commonly known as ‘mullein’ is part of a large family of Scrophulariaceae consisting of more than 360 species and theirs anti inflammatory effects
found that a significant decrease of the expression and activity of iNOS, extracellular O(2) (-) production, SOD, CAT and GPx activity when the cells were treated with verbascoside. Based on these results it is hypothesized that verbascoside has antiinflammatory properties since it reduces the production of superoxide radicals and consequently reduces the activity of iNOS, according to “Antiinflammatory effects in THP-1 cells treated with verbascoside” by
Speranza L, Franceschelli S, Pesce M, Reale M, Menghini L, Vinciguerra I, De Lutiis MA, Felaco M, Grilli A.(43).

3. Cayenne
Cayenne is also known as Cayenne Pepper, a red, hot chili pepper, belonging to Capsicum annuum, the family Solanaceae, native to sub-tropical and tropical regions. It has been used in traditional medicine to increases metabolism, enhance circulatory system and stomach and the intestinal tract, adjust blood pressure, lower LDL cholesterol and triglycerides, treat frostbite, muscles, arthritis, rheumatism, low back pain, strains, sprains, bruises and neuralgia, etc.
a. Antioxidants
C. annuum var. cerasiferum has showed a significant antioxidant activity evaluated by the β-carotene bleaching test (IC(50) of 3.1 μg/ml). The lipophilic fraction of both C. annuum var. acuminatum and C. annuum var. cerasiferum exhibited an interesting and selective inhibitory activity against α-amylase (IC(50) of 6.9 and 20.1 μg/ml, respectively), according to the study of “Comparative study on the chemical composition, antioxidant properties and hypoglycaemic activities of two Capsicum annuum L. cultivars (Acuminatum small and Cerasiferum)’ by Tundis R, Loizzo MR, Menichini F, Bonesi M, Conforti F, Statti G, De Luca D, de Cindio B, Menichini F.(44)
b. Airway Inflammation
Methanolic C. annuum L. extract (CAE) has attenuated ovalbumin-induced increases in NF-κB activity in lungs. Collectively, these results suggest that CAE may be an effective oral treatment for allergic airway inflammation by virtue of its antioxidant activity, according to the study of “Capsicum annuum L. Methanolic Extract Inhibits Ovalbumin-Induced Airway Inflammation and Oxidative Stress in a Mouse Model of Asthma” by Jang HY, Kim SM, Yuk JE, Kwon OK, Oh SR, Lee HK, Jeong H, Ahn KS.(45)
cv. Anti inflammatory Effects
C. baccatum juice has significantly decreased leucocyte and neutrophil migration, exudate volume and protein and LDH concentration in pleural exudates of a pleurisy model and inhibited neutrophil migration and reduced the vascular permeability on carrageenan-induced peritonitis, according to the study of “Anti-inflammatory effects of red pepper (Capsicum baccatum) on carrageenan- and antigen-induced inflammation’ by Spiller F, Alves MK, Vieira SM, Carvalho TA, Leite CE, Lunardelli A, Poloni JA, Cunha FQ, de Oliveira JR.(46).

All Forms of Arthritis are Curable
You Can Eliminate Osteoarthritis
By addressing the Underlying Causes through Clinical Trials and Studies

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Super foods Library, Eat Yourself Healthy With The Best of the Best Nature Has to Offer

Sunday, April 3, 2016

Most Common Disease of 50plus: The Clinical trials and Studies of Musculo-Skeletal disorders(MSDs) - Osteoarthritis: The Misdiagnosis and delay diagnosis

Kyle J. Norton (Scholar)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

Musculoskeletal disorders (MSDs) are medical condition mostly caused by work related occupations and working environment, affecting patients’ muscles, joints, tendons, ligaments and nerves and developing over time. A community sample of 73 females and 32 males aged 85 and over underwent a standardised examination at home. Musculoskeletal pain was reported by 57% of those interviewed. A major restriction of joint movement range was frequent in the shoulder but uncommon in other joints(1).

Types of Musculo-Skeletal disorders in elder(2)

1. Osteoarthritis
2. Gout
3. Rheumatoid Arthritis
4. Polymalagia Arthritis
5. Cervical myleopathy and spinal canal stenosis
6. Osteoporosis
7. Low back pain
8. Fibromyalgia            



                                                      Osteoarthritis


Osteoarthritis (OA), a form of arthritis, is defined as a condition of as a result of aging causes of wear and tear on a joint, affecting over 25 million people in the United States in alone. University of Porto Medical School indicated that one must understand the differences in prevalence and incidence estimates of osteoarthritis (OA), according to case definition, in knee, hip and hand joints(3).
The characteristics of osteoarthritis are aching pain(5), stiffness(6), or difficulty of moving the joint or joints(7). The pain usually gets worse in change of weather, at night and in the advanced diseases, the pain can occur even at rest(8). Today management of osteoarthritis (OA) focuses on pain relief and improved physical function through pharmacological, non pharmacological, and surgical treatments(4).



       The Misdiagnosis and delay diagnosis


Although musculoskeletal disorders is very common with irreversible damage due to osteoarthritis in elder found in evidences of all X ray, misdiagnosis is rare but it can happen. According to the Mount Sinai Medical Center, potentially reversible causes of osteoarthritis for the problem are too often ignored, and a misdiagnosis of osteoarthritis prevents or delays effective treatment of the actual underlying problem(174).
According to Dr. O'Duffy JD., there was a diagnostic problems of rheumatic disease in patients over 60 years of age, including patient with osteoarthritis, and these problems can be prevent if the doctors have taken accounted the history and physical examination alone, with the laboratory and x-ray findings providing supportive evidence(175).



Arthritis Is Curable
You Can Eliminate Osteoarthritis
By addressing the Underlying Causes through Clinical Trials and Studies

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months


Super foods Library, Eat Yourself Healthy With The Best of the Best Nature Has to Offer recommended by Kyle J. Norton

Back to Kyle J. Norton Home page http://kylejnorton.blogspot.ca


References
(1) Prevalence of rheumatic symptoms, rheumatoid arthritis, ankylosing spondylitis, and gout in Shanghai, China: a COPCORD study by Dai SM1, Han XH, Zhao DB, Shi YQ, Liu Y, Meng JM.(PubMed)
(2) Musculoskeletal Disorders in the Elderly by Ramon Gheno, Juan M. Cepparo, Cristina E. Rosca,1 and Anne Cotten(PMC)
(3) The effect of osteoarthritis definition on prevalence and incidence estimates: a systematic review by Pereira D1, Peleteiro B, Araújo J, Branco J, Santos RA, Ramos E.(PubMed)
(4) Effect of therapeutic aquatic exercise on symptoms and function associated with lower limb osteoarthritis: systematic review with meta-analysis by Waller B1, Ogonowska-Slodownik A2, Vitor M3, Lambeck J4, Daly D5, Kujala UM6, Heinonen A7.(PubMed)
(5) Effects of therapeutic ultrasound on pain, physical functions and safety outcomes in patients with kneeosteoarthritis: A systematic review and meta-analysis by Zhang C1, Xie Y2, Luo X3, Ji Q3, Lu C3, He C4, Wang P3.(PubMed)
(6) Oral intake of purple passion fruit peel extract reduces pain and stiffness and improves physical function in adult patients with knee osteoarthritis by Farid R1, Rezaieyazdi Z, Mirfeizi Z, Hatef MR, Mirheidari M, Mansouri H, Esmaelli H, Bentley G, Lu Y, Foo Y, Watson RR.(PubMed)
(7) Functional ability, mobility, and pain before and after knee replacement in patients aged 75 and older: a cross-sectional study by Limnell K1, Jämsen E, Huhtala H, Jäntti P, Puolakka T, Jylhä M.(PubMed)
(8) The symptoms of OA and the genesis of pain by David J. Hunter, MBBS PhD,1,2 Jason J. McDougall, BSc PhD,3 and Francis J. Keefe4(PubMed)

(174) Osteoarthritis as a misdiagnosis in elderly patients by Spiera H1.(PubMed)
(175) Differential diagnosis of rheumatic disease in the elderly by O'Duffy JD(PubMed)

The Best Cabbage, Flax Seed and Panax Ginseng Powder for Prevention and Treatment of Urogenital atrophy

Kyle J. Norton(Scholar, Master of Nutrients), all right reserved.
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

The Incredible and Effective smoothie for Reduced Risk and Treatment of Urogenital atrophy
Yield: 2 servings (about 8 ounces each)
1   cup cabbage for t
1/4 cup flax seed
1/4 cup honey for tast
1 cup Panax ginseng drink (Make from 2 grams of Panax ginseng powder and a cup of hot water lipped for 5 minutes, and let cool to room temperature)
1. Place all ingredients in a blender and puree about 1 minute
2. Blend on high speed about 1 minute or until the mixture is thick and the ice is well crushed.
3. Serve immediately

Urogenital atrophy is a condition of changes in the vagina and urethra due to declining estrogen levels in these tissues.

The finding of a natural source for reduced risk and treatment of Urogenital atrophy to replace the oral hormone replacement therapy (HRT), has been running into many obstacles, many ingredients showed initially with promising result in animal studies have not produced same potentials in either large sample size and mutli centers human trials.

Strong evidences of number of renowned institutions suggested that natural sources, such as Isoflavones found in legume, serotonin found in flax seed processed alleviating vasomotor episodes, attenuating bone loss, and stimulating vaginal epithelial maturation,. according to the joint study lead by The Chiang Mai University(1).

Dr.Sobenin IA and researcher at the Russian Cardiology Research and Production Complex, said, "Phytoestrogens are often considered as a possible alternative to hormone replacement therapy, since they are believed to alleviate some symptoms of menopause, such as, therosclerosis and atherosclerosis-related diseases through multiple mechanisms"(2).
In Fact, Phytoestrogens can play an important role in symptoms of menopause including fatigue, insomnia, problems with concentrations and depression symptoms and on women organism during menopausal period(3).

Levels of serotonin found abundantly in flax seed, is associated to reduced risk, frequency and severity of vasomotor symptoms in menopausal women(4). According to the Massachusetts General Hospital, serotonin-norepinephrine reuptake inhibitor duloxetine significant improve dpression, vasomotor symptoms, sleep, anxiety, and pain after 8 weeks(5).

Dr. Joffe H and the research team at the joint study lead Harvard Medical School, low-dose oral estradiol and venlafaxine(serotonin-norepinephrine reuptake inhibitor ) are effective treatments for VMS in women during midlife(6).

Another selective serotonin reuptake inhibitor, escitalopram, also alleviated the frequency, severity, and bother of menopausal hot flashes in the study of 205 women (95 African American; 102 white; 8 other) between July 2009 and June 2010.(7).

Ginseng is a slow-growing perennial plants with fleshy roots, the genus Panax, belongings to the family Araliaceae. Depending to the climate where it grows, ginseng can be classified mainly into Panax ginseng Asian ginseng (root), Red ginseng, wild ginseng, American ginseng (root). The herb(Panax ginseng) may be used for treatment of reduced estrogen levels due to aging in women becaused of its ginsenoside Rb in exhibited phytoestrogen like effects(8).
According to the China Pharmaceutical University in ovariectomized mice study suggested that ginsenoside Rb1 (Rb1) isolated from Panax ginseng, increased 5-hydroxytryptamine (5-HT) concentration via its estrogen-like effect(9).

The effectiveness of Cabbage, Flax Seed and Panax Ginseng Powder may serve as cornerstones of pharmaceutical target for further studies in production of a potential medication for for Reduced Risk of Consequences of  Urogenital atrophy with little or no adverse effects.

Women who are pregnancy may want to stop drinking excessively. Otherwise, intake of
Smoothie of Cabbage, Flax Seed and Panax Ginseng Powde may Reduced Risk and treatment of Urogenital atrophy.
Life style and dietary patter change are recommended.

All Forms of Arthritis are Curable

Ovarian Cysts And PCOS Elimination

References
(1) Open, non-controlled clinical studies to assess the efficacy and safety of a medical device in form of gel topically and intravaginally used in postmenopausal women with genital atrophy by Morali G1, Polatti F, Metelitsa EN, Mascarucci P, Magnani P, Marrè GB.(PubMed)
(2) Phytoestrogen-Rich Dietary Supplements in Anti-Atherosclerotic Therapy in Postmenopausal Women by Sobenin IA1, Myasoedova VA, Orekhov AN.(PubMed)
(3) [Phytoestrogens--whether can they be an alternative to hormone replacement therapy for women during menopause period?].[Article in Polish] by Dittfeld A, Koszowska A, Brończyk AP, Nowak J, Gwizdek K, Zubelewicz-Szkodzińska B.(PubMed)
(4) Methods for the design of vasomotor symptom trials: the menopausal strategies: finding lasting answers to symptoms and health network by Newton KM1, Carpenter JS, Guthrie KA, Anderson GL, Caan B, Cohen LS, Ensrud KE, Freeman EW, Joffe H, Sternfeld B, Reed SD,Sherman S, Sammel MD, Kroenke K, Larson JC, Lacroix AZ.(PubMed)
(5) Treatment of depression and menopause-related symptoms with the serotonin-norepinephrine reuptake inhibitor duloxetine. by Joffe H1, Soares CN, Petrillo LF, Viguera AC, Somley BL, Koch JK, Cohen LS.(PubMed)
(6) Low-dose estradiol and the serotonin-norepinephrine reuptake inhibitor venlafaxine forvasomotor symptoms: a randomized clinical trial by Joffe H1, Guthrie KA2, LaCroix AZ2, Reed SD3, Ensrud KE4, Manson JE5, Newton KM6, Freeman EW7, Anderson GL2, Larson JC2, Hunt J2,Shifren J8, Rexrode KM5, Caan B9, Sternfeld B9, Carpenter JS10, Cohen L8(PubMed)
(7) Efficacy of escitalopram for hot flashes in healthy menopausal women: a randomized controlled trial. by Freeman EW1, Guthrie KA, Caan B, Sternfeld B, Cohen LS, Joffe H, Carpenter JS, Anderson GL, Larson JC, Ensrud KE, Reed SD, Newton KM, Sherman S, Sammel MD, LaCroix AZ.(PubMed)
(8) Beneficial estrogen-like effects of ginsenoside Rb1, an active component of Panax ginseng, on neural 5-HT disposition and behavioral tasks in ovariectomized mice by Hao K1, Gong P1, Sun SQ1, Hao HP1, Wang GJ1, Dai Y2, Liang Y1, Xie L1, Li FY1.(PubMed)
(9) Mechanism-based pharmacokinetic-pharmacodynamic modeling of the estrogen-like effect of ginsenoside Rb1 on neural 5-HT in ovariectomized mice by Hao K1, Gong P, Sun SQ, Hao HP, Wang GJ, Dai Y, Chen YC, Liang Y, Xie L, Li FY, Li HY.(PubMed)

Most Common Diseases of elder: Respiratory Pleural disease: Pleural Plaques - The Preventive Antioxidants

Kyle J. Norton(Scholar and Master of Nutrients, all right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

                                          Respiratory Disease

Respiratory Disease is defined as medical conditions, affecting the breathing organ and tissues including Inflammatory lung disease, Obstructive lung diseases, Restrictive lung diseases, Respiratory tract infections, trachea, bronchi, bronchioles, alveoli, the nerves and muscles breathing, etc,.

                   Pleural disease: Pleural Plaques

The pleura is a thin tissue covered by a layer of cells (mesothelial cells) that surrounds the lungs and lines the inside of the chest wall.
Pleural plaques is a medical condition as a result of exposure to asbestos that lead to accumulated plagues within the pleural cavity(a). Many diseases such as pneumonia, breast cancer, and heart failure can affect the pleural space.,therefore, it is often a secondary effect of another disease process.


The Preventive Antioxidants 

1. Matonon
In the study to evaluate the Oxidative stress of thirty-six consecutive patients with clinically stable moderate to very severe COPD (30 men; mean±S.D.=66.6±7.8yr) randomized to receive 3mg melatonin (N=18) or placebo for 3 months found that dyspnea was improved by melatonin (P=0.01), despite no significant changes in lung function or exercise capacity(33).

2. Resveratrol
According to the study bythe John Hunter Hospital, Newcastle, Antioxidants provide protection against the damaging effects of oxidative stress and thus may be useful in the management of inflammatory airways disease. Resveratrol, a polyphenol that demonstrates both antioxidative and anti-inflammatory functions, has been shown to improve outcomes in a variety of diseases(34).

3. Vitamin C
Although many epidemiological studies indicate protective effect of vitamin C against a variety of human malignancies its mechanism(s) of action is questionable, the presented results show that the part of its effect may be accomplished by mononuclear cells, as necessary participants in body defence. Namely, in a long-term in vitro assay we tested vitamin C influence on random migration ability of malignant pleural effusion mononuclears (PEM) obtained from breast cancer patients. Vitamin C in a dose- (50-500 micrograms) and time-dependent (4-44 h) manner inhibited PEM motility, suggesting that immobilization of cells in situ may contribute to its beneficial effect in human cancers, according to the Institute of Physiology, Medical Faculty, Belgrade(35).

4. L-Arginine
According to the study by Hôpital Cochin, Paris, in the study to assess the vNO generation in the course of two acute, non immune, inflammatory reactions (pleurisy induced by rat isologous serum and carrageenan) by means of nitrite measurement in pleural exudate from 0.5 to 24 h, indicated that NO release varied time-dependently, similarly for the two inflammatory reactions. A first, but transient, peak was reached in 30 min while a second peak, more sustained, began at the fourth hour and was maximum at the tenth. Kinetic evolution of NO release was consistent with activation, in a first step, of a constitutive NO synthase probably from endothelial origin (inhibited by 2-Methyl-2-Thiopseudourea sulfate but not by dexamethasone) and with activation, in a second wave, of inducible NOS from endothelial and exudative cells. NO release was potentiated by administration per os of L-Arginine and seems to be involved in the evolution of acute inflammatory reactions and oxygen metabolite production(36).

5. Other antioxidants
According to the study by the University of Rochester Medical Center, antioxidant and/or anti-inflammatory agents such as thiol molecules (glutathione and mucolytic drugs, such as N-acetyl-L-cysteine and N-acystelyn), dietary polyphenol (curcumin-diferuloylmethane, a principal component of turmeric), resveratrol (a flavanoid found in red wine), green tea (theophylline and epigallocatechin-3- gallate), ergothioneine (xanthine and peroxynitrite inhibitor), quercetin, erdosteine and carbocysteine lysine salt, have been reported to control NF-kappaB activation, regulation of glutathione biosynthesis genes, chromatin remodeling and hence inflammatory gene expression. Specific spin traps such as alpha-phenyl-N-tert-butyl nitrone, a catalytic antioxidant (ECSOD mimetic), manganese (III) meso-tetrakis (N,N’-diethyl-1,3-imidazolium-2-yl) porphyrin (AEOL 10150 and AEOL 10113), and a SOD mimetic M40419 have also been reported to inhibit cigarette smoke-induced inflammatory responses in vivo(37).

All Forms of Arthritis are Curable
You Can Eliminate Osteoarthritis
By addressing the Underlying Causes through Clinical Trials and Studies

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Super foods Library, Eat Yourself Healthy With The Best of the Best Nature Has to Offer