Medical Advisor Journals

Wednesday, April 6, 2016

Most Common Diseases of 50plus: Pulmonary vascular disease(Respiratory disease): Pulmonary edema- Signs and Symptoms

Kyle J. Norton(Scholar and Master of Nutrients, all right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

Respiratory Disease

Respiratory Disease is defined as medical conditions, affecting the breathing organ and tissues including Inflammatory lung disease, Obstructive lung diseases, Restrictive lung diseases, Respiratory tract infections, trachea, bronchi, bronchioles, alveoli, the nerves and muscles breathing, etc,.

Pulmonary vascular disease: Pulmonary edema

Pulmonary vascular disease is defined as a condition of blood flow to the lung’s artery is blocked suddenly due to a blood clot somewhere in the body, including pulmonary embolism, chronic thromboembolic disease, pulmonary arterial hypertension, pulmonary veno-occlusive disease, pulmonary arteriovenous malformations, pulmonary edema, etc.

Pulmonary edema is defined as a condition of fluid accumulation in the air spaces and parenchyma of the lungs of that can lead to difficult of breathing and respiratory failure.

Signs and Symptoms

Acute pulmonary edema can be classified as either cardiogenic or noncardiogenic or both. Cardiogenic pulmonary edema occurs when the pulmonary capillary hydrostatic pressure exceeds plasma oncotic pressure. Noncardiogenic pulmonary edema occurs when pulmonary capillary permeability is increased(a).
1. Shortness of breath, precipitation, high systolic blood pressure, and chest pain
In the study to
1) describe the prehospital clinical presentation and management of patients with a clinical diagnosis of APE and
2) compare the accuracy of coding of APE by paramedics against the emergency department (ED) medical discharge diagnosis, including a retrospective cohort of all patients who had episodes identified as APE by ambulance paramedics and were transported to a metropolitan hospital ED in 2011, found that four hundred ninety-five patients were transported to an ED with APE identified by the paramedics as the primary problem code. Shortness of breath, crepitations, high systolic blood pressure, and chest pain were the most common presenting signs and symptoms. Pink frothy sputum was rare (3% of patient episodes of APE)(1).

2. Severe respiratory distress with evident inability to adequately ventilate and/or oxygenate
According to the study by the University Hospital of Pisa there is a series of study with the use of intravenous atenolol, a short-acting cardioselective beta-adrenergic antagonist, to treat acute pulmonary edema in the prehospital setting. Four patients with a documented history of cardiac disease and one patient with unknown cardiac issues experienced severe respiratory distress and presented with pulmonary edema; the local emergency medical service was utilized. In all of the patients, the saturation of peripheral oxygen (SpO2) was severely low, and the patients were rapidly treated with oxygen, diuretics, morphine, and nitrates(2).

3. According to the article by Jack Hirsh, MD; John Hoak, MD, patients who survive an acute PE are at high risk for recurrent PE and for the development of pulmonary hypertension and chronic cor pulmonale, which occurs in up to 70% of patients and carries its own attendant mortality and morbidity. Massive PE causes hypotension due to acute cor pulmonale, but the physical examination findings early in submassive PE may be completely normal. Initially, abnormal physical findings are absent in most patients with PE. After 24-72 hours, loss of pulmonary surfactant often causes atelectasis and alveolar infiltrates that are indistinguishable from pneumonia on clinical examination and by x-ray. New wheezing may be appreciated. If pleural lung surfaces are affected, a pulmonary rub may be heard.

The spontaneous onset of chest wall tenderness without a good history of trauma is always worrisome, because patients with PE may have chest wall tenderness as the only physical finding.
In patients with massive PE, the incidence of physical signs has been reported as follows:
96% have tachypnea (respiratory rate >16/min)
58% develop rales 53% have an accentuated second heart sound 44% have tachycardia (heart rate >100/min)
43% have fever (temperature >37.8° C)
36% have diaphoresis
34% have an S3 or S4 gallop
32% have clinical signs and symptoms suggesting thrombophlebitis
24% have lower extremity edema
23% have a cardiac murmur
19% have cyanosis (3)

All Forms of Arthritis are Curable
You Can Eliminate Osteoarthritis
By addressing the Underlying Causes through Clinical Trials and Studies

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Super foods Library, Eat Yourself Healthy With The Best of the Best Nature Has to Offer

Sources
(a) http://www.ncbi.nlm.nih.gov/pubmed/19739476
(1) http://www.ncbi.nlm.nih.gov/pubmed/23484502
(2) http://www.ncbi.nlm.nih.gov/pubmed/23607890
(3) http://www.mac-paper.com/WebSiteFiles/Miscellaneous/PE.html#Anchor-Authored%20by%20Cr-42694

Tuesday, April 5, 2016

Most Common Disease of 50Plus: The Clinical trials and Studies of Musculo-Skeletal disorders(MSDs) - Osteoarthritis: The Diet

Kyle J. Norton (Scholar)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

Musculoskeletal disorders (MSDs) are medical condition mostly caused by work related occupations and working environment, affecting patients’ muscles, joints, tendons, ligaments and nerves and developing over time. A community sample of 73 females and 32 males aged 85 and over underwent a standardised examination at home. Musculoskeletal pain was reported by 57% of those interviewed. A major restriction of joint movement range was frequent in the shoulder but uncommon in other joints(1).

Types of Musculo-Skeletal disorders in elder(2)
1. Osteoarthritis
2. Gout
3. Rheumatoid Arthritis
4. Polymalagia Arthritis
5. Cervical myleopathy and spinal canal stenosis
6. Osteoporosis
7. Low back pain
8. Fibromyalgia

Osteoarthritis

Osteoarthritis (OA), a form of arthritis, is defined as a condition of as a result of aging causes of wear and tear on a joint, affecting over 25 million people in the United States in alone. University of Porto Medical School indicated that one must understand the differences in prevalence and incidence estimates of osteoarthritis (OA), according to case definition, in knee, hip and hand joints(3).
The characteristics of osteoarthritis are aching pain(5), stiffness(6), or difficulty of moving the joint or joints(7). The pain usually gets worse in change of weather, at night and in the advanced diseases, the pain can occur even at rest(8). Today management of osteoarthritis (OA) focuses on pain relief and improved physical function through pharmacological, non pharmacological, and surgical treatments(4).

The Prevention and management Diet

The aims of the diet is to provide protection to avoid elevation of the inflammatory effects(139) in induced-degeneration causes of osteoarthritis(133)(134)
1. Green tea
Epigallocatechin 3-gallate (EGCG), according to the College of Pharmacy, found abundantly in green tea showed to exhibit its anti anti-rheumatic activity in patients with joint diseases(140) through its antioxidant property(141).

2. Salmon
Salmon is the common name for Salmonidae, born in fresh water, migrate to the ocean, then travel thousands of miles in the deep sea cold water throughout their life cycle and within five years returning to the exacted location where they were born to reproduce and die.
a. Weight loss
Intake of salmon oil has shown to induce body weight loss in mice, according to the study by University of Washington(142). N3 long-chain polyunsaturated fatty acids (n3-LCPUFA) enhanced body weight loss, at the end of the 1-month period in 16 children through deduction of insulin resistance(143).

b. Antioxidants
Megadoses of vitamin E, found in salmon oil exhibited pro-oxidative activity, through increased the anti-oxidative capacity of the liver(144).

c. Omega 3 fatty acids
Omega 3 fatty acids is necessary to maintain the ratio of good and bad cholesterol(145), thus reducing the risk of cholesterol inflammation(146)(148) cause of heart diseases (147) and osteoarthritis(133)(134).

d. Anti inflammation
Omega 3 fatty acids not only reduces the risk of inflammatory effects on our joints and improved blood flow(149), by regulating the migration of inflammatory cells(139), but also reduce the elevation of the proinflammatory leukotriene LTB(4) causes of autoimmune diseases(150).

3. Walnut tree
Walnut tree, cultivated for its nut and kernel and for commercial purpose all over the world, is one of the Genus plant belong to the family Juglandaceae about 30–130 ft).
a. Antioxidant effects(151)(152)
Even-though walnuts consumption did not only significantly change the plasma antioxidant capacity of healthy, well-nourished older adults through its polyphenols in inhibitiobn plasma and LDL oxidation(151) but chronic consumption, it improved postprandial serum antioxidants and biomarkers of oxidative status(152) through its antioxidant linoleic acid and pyridoxal phosphate in enhancing total plasma thiols(151).

b. Inflammation defense(153)
Intake of walnuts is shown to promote manganese superoxide dismutase (MnSOD), an enzyme located in mitochondria(154), is the key enzyme in protection of the energy-generating mitochondria from oxidative damage caused by free radicals(155).

c. Diabetes risk

Adiponectin found abundantly in walnut-enriched meal plays an important causal role in insulin resistance and metabolic syndrome(156). Diabetes in older adult is shown to associate increased risk of osteoarthritis(157).

4. Dulse
Dulse, commonly used in Ireland and Atlantic Canada both as foods and medicines, is a red seaweed of genus Palmaria, belong to Family Palmariaceae grown attached to rocks by a “holdfast” in the North Atlantic and Northwest Pacific. Dulse is found in many health food stores or fish markets or can be ordered directly from local distributors.
a. Health benefits
Seaweeds, including dulse, showed to consist a important functional activities, such as antioxidant(158)(160)(161), antimutagenic(159)(162) and anticoagulant effect(160), antitumor activity(160), and modification of lipid metabolism(161).
b. Antioxidants
Dulse extracts showed to inhibit certain lipid peroxidations(162).
c. Weigh loss
As a rich source of fiber, dulse enhances the process of digestion, for making the stomach feeling fullness, thus reducing the risk of insulin cause of food craving(163).

5. Lime (Lemon)
Lime, a around shape with green to yellow in color and 3–6 cm in diameter, is a species of Citrus Aurantifolia, belongs to the family Rutaceae, native to Southeast Asia.
a. Antioxidant
Lime flower extract may contain high levels of antioxidant(164)(165) but lesser than the ethanol extract of cinnamon(166).
b. Vitamin C
Besides preventing the breaking off small vein cause of hardening of the vessel wall(167), vitamin C also improves the digestive system in maximum absorption of vital nutrients and plays an important role in enhancing immune system fighting against the forming of free radicals that cause muscle damage(168). According to the University of Limerick, prior supplementation with dietary antioxidants, such as vitamin C and E may ameliorate muscle functional decrements subsequent to eccentric muscle contraction(169).

6. Dairy Products
Dairy products contain high amount of nutrients, it also has measure amount of vitamin D of which is necessary for the body in calcium absorption(170). Intake of dairy products per day, according to joint study including Université Libre de Bruxelles appears to be safe and may confer a favourable benefit with regard to bone health, such as osteoarthritis(172), rheumatoid arthritis(170).
In elderly Fracture risk, according to the Geneva University Hospitals and Faculty of Medicine, improved bone growth is influenced by dietary intake, particularly of calcium and protein such as Dairy products, yogurts are essential to achieve optimal peak bone mass during skeletal growth and to prevent bone loss(171). Recommendation of consuming 3 servings of dairy products per day during childhood and adolescence, has shown to improve bone health and reduce the risk of fractures in later life(171).
In the observation of a significant dose-response relationship between baseline milk intake and adjusted mean decrease of JSW in women, researcher at the Brigham and Women's Hospital and Harvard Medical School, Boston, showed that frequent milk consumption may be associated with reduced OA progression in women and delay in knee OA progression(173).

Arthritis Is Curable
You Can Eliminate Osteoarthritis
By addressing the Underlying Causes through Clinical Trials and Studies

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Super foods Library, Eat Yourself Healthy With The Best of the Best Nature Has to Offer recommended by Kyle J. Norton

Back to Kyle J. Norton Home page http://kylejnorton.blogspot.ca

References
(1) Prevalence of rheumatic symptoms, rheumatoid arthritis, ankylosing spondylitis, and gout in Shanghai, China: a COPCORD study by Dai SM1, Han XH, Zhao DB, Shi YQ, Liu Y, Meng JM.(PubMed)
(2) Musculoskeletal Disorders in the Elderly by Ramon Gheno, Juan M. Cepparo, Cristina E. Rosca,1 and Anne Cotten(PMC)
(3) The effect of osteoarthritis definition on prevalence and incidence estimates: a systematic review by Pereira D1, Peleteiro B, Araújo J, Branco J, Santos RA, Ramos E.(PubMed)
(4) Effect of therapeutic aquatic exercise on symptoms and function associated with lower limb osteoarthritis: systematic review with meta-analysis by Waller B1, Ogonowska-Slodownik A2, Vitor M3, Lambeck J4, Daly D5, Kujala UM6, Heinonen A7.(PubMed)
(5) Effects of therapeutic ultrasound on pain, physical functions and safety outcomes in patients with kneeosteoarthritis: A systematic review and meta-analysis by Zhang C1, Xie Y2, Luo X3, Ji Q3, Lu C3, He C4, Wang P3.(PubMed)
(6) Oral intake of purple passion fruit peel extract reduces pain and stiffness and improves physical function in adult patients with knee osteoarthritis by Farid R1, Rezaieyazdi Z, Mirfeizi Z, Hatef MR, Mirheidari M, Mansouri H, Esmaelli H, Bentley G, Lu Y, Foo Y, Watson RR.(PubMed)
(7) Functional ability, mobility, and pain before and after knee replacement in patients aged 75 and older: a cross-sectional study by Limnell K1, Jämsen E, Huhtala H, Jäntti P, Puolakka T, Jylhä M.(PubMed)
(8) The symptoms of OA and the genesis of pain by David J. Hunter, MBBS PhD,1,2 Jason J. McDougall, BSc PhD,3 and Francis J. Keefe4(PubMed)

(141) Preparation and antioxidant activity of green tea extract enriched in epigallocatechin (EGC) and epigallocatechin gallate (EGCG) by Hu J1, Zhou D, Chen Y.(PubMed)
(142) Genetically determined body weight loss in mice fed diets containing salmon oil by LeBoeuf RC1, Veldee MS.(PubMed)
(143) Supplementation of n3 long-chain polyunsaturated fatty acid synergistically decreases insulin resistance withweight loss of obese prepubertal and pubertal children by López-Alarcón M1, Martínez-Coronado A, Velarde-Castro O, Rendón-Macías E, Fernández J.(PubMed)
(144) Effects of megadoses of dietary vitamin E on the antioxidant status of rats fed lard or salmon oil by Flader D1, Brandsch C, Hirche F, Eder K.(PubMed)
(145) Omega 3 fatty acids promote macrophage reverse cholesterol transport in hamster fed high fat diet by Kasbi Chadli F1, Nazih H, Krempf M, Nguyen P, Ouguerram K.(PubMed)
(146) Cholesterol, inflammation and innate immunity by Tall AR1, Yvan-Charvet L2.(PubMed)
(147) In vitro fatty acid enrichment of macrophages alters inflammatory response and net cholesterol accumulation by Wang S1, Wu D, Lamon-Fava S, Matthan NR, Honda KL, Lichtenstein AH.(PubMed)
(148) Uncoupling lipid metabolism from inflammation through fatty acid binding protein-dependent expression of UCP2. byXu H1, Hertzel AV1, Steen KA1, Wang Q2, Suttles J3, Bernlohr DA4.(PubMed)
(149) Low-dose aspirin and omega-3 fatty acids improve uterine artery blood flow velocity in women with recurrent miscarriage due to impaired uterine perfusion by Lazzarin N1, Vaquero E, Exacoustos C, Bertonotti E, Romanini ME, Arduini D.(PubMed)
(150) Omega-3 fatty acids in inflammation and autoimmune diseases. by Simopoulos AP1.(PubMed)
(151) Chronic and acute effects of walnuts on antioxidant capacity and nutritional status in humans: a randomized, cross-over pilot study by McKay DL1, Chen CY, Yeum KJ, Matthan NR, Lichtenstein AH, Blumberg JB.(PubMed)
(152) Effect of a walnut meal on postprandial oxidative stress and antioxidants in healthy individuals by Haddad EH1, Gaban-Chong N, Oda K, Sabaté J.(PubMed)
(153) Olive oil and walnut breakfasts reduce the postprandial inflammatory response in mononuclear cells compared with a butter breakfast in healthy men by Jiménez-Gómez Y1, López-Miranda J, Blanco-Colio LM, Marín C, Pérez-Martínez P, Ruano J, Paniagua JA, Rodríguez F, Egido J, Pérez-Jiménez F.(PubMed)
(154) manganese(The world healthier foods)
(155) The role of manganese superoxide dismutase in inflammation defense by Li C1, Zhou HM(PubMed)
(156) An acute intake of a walnut-enriched meal improves postprandial adiponectin response in healthy young adults by Lozano A1, Perez-Martinez P, Marin C, Tinahones FJ, Delgado-Lista J, Cruz-Teno C, Gomez-Luna P, Rodriguez-Cantalejo F, Perez-Jimenez F, Lopez-Miranda(PubMed)
(157) Links between osteoarthritis and diabetes: implications for management from a physical activity perspective by Piva SR1, Susko AM2, Khoja SS2, Josbeno DA2, Fitzgerald GK2, Toledo FG3.(PubMed)
(158) Antioxidant and cytotoxic activities of three species of tropical seaweeds by Chia YY1, Kanthimathi MS2,3, Khoo KS4, Rajarajeswaran J5, Cheng HM6, Yap WS7.(PubMed)
(159) Brown seaweed fucoidan: biological activity and apoptosis, growth signaling mechanism in cancer by Senthilkumar K1, Manivasagan P, Venkatesan J, Kim SK.(PubMed)
(160) Anticoagulant, Antioxidant and Antitumor Activities of Heterofucans from the Seaweed Dictyopteris delicatul by Kaline Dantas Magalhaes,1,2,† Leandro Silva Costa,1,3,† Gabriel Pereira Fidelis,1 Ruth Medeiros Oliveira,1 Leonardo Thiago Duarte Barreto Nobre,1 Nednaldo Dantas-Santos,1,2 Rafael Barros Gomes Camara,1 Ivan Rui Lopes Albuquerque,1,2 Sara Lima Cordeiro,1 Diego Araujo Sabry,1 Mariana Santana Santos Pereira Costa,1 Luciana Guimaraes Alves,1 and Hugo Alexandre Oliveira Rocha1,2(PMC)
(161) [Nutritional evaluation and physiological effects of edible seaweeds].[Article in Spanish] by Jiménez-Escrig A1, Goñi Cambrodón I.(PubMed)
(162) Extracts from dulse (Palmaria palmata) are effective antioxidants and inhibitors of cell proliferation in vitro by Yuan YV1, Carrington MF, Walsh NA.(PubMed)
(163) THE WORLD HEALTHIEST FOODS - PART II - VEGETABLES by Kyle J. Norton
(164) Role of bilirubin as antioxidant in neonatal jaundice and effect of ethanolic extract of sweet lime peel on experimentally induced jaundice in rat by Nag N1, Halder S, Chaudhuri R, Adhikary S, Mazumder S.(PubMed)
(165) Phytochemicals and antioxidant capacity of tortillas obtained after lime-cooking extrusion process of whole pigmented mexican maize by Aguayo-Rojas J1, Mora-Rochín S, Cuevas-Rodríguez EO, Serna-Saldivar SO, Gutierrez-Uribe JA, Reyes-Moreno C, Milán-Carril(PubMed)
(166) Antioxidant and anticholinesterase activities of eleven edible plants by Boğa M1, Hacıbekiroğlu I, Kolak U.(PubMed)
(167) Aging Hearts and Arteries: A Scientific Quest, Chapter 4: Blood Vessels and Aging: The Rest of the Journey(NIH)
(168) Does antioxidant vitamin supplementation protect against muscle damage? by McGinley C1, Shafat A, Donnelly AE(PubMed)
(169) Effects of dietary supplementation with vitamins C and E on muscle function during and after eccentric contractions in humans by Shafat A1, Butler P, Jensen RL, Donnelly AE.(PubMed)
(170) Effects of Dairy Products Consumption on Health: Benefits and Beliefs-A Commentary from the Belgian Bone Club and the European Society for Clinical and Economic Aspects of Osteoporosis, Osteoarthritis and Musculoskeletal Diseases by Rozenberg S1, Body JJ2, Bruyère O3, Bergmann P4, Brandi ML5, Cooper C6,7, Devogelaer JP8, Gielen E9, Goemaere S10, Kaufman JM11, Rizzoli R12,Reginster JY13(PubMed)
(171) Dairy products, yogurts, and bone health by Rizzoli R1.(PubMed)
(172) Got osteoarthritis? Maybe milk can help by Sahni S1, McLean RR.(PubMed)
(173) Milk consumption and progression of medial tibiofemoral knee osteoarthritis: data from the Osteoarthritis Initiative by Lu B1, Driban JB, Duryea J, McAlindon T, Lapane KL, Eaton CB(PubMed)

The Wonderful Smoothie of Cooked Sweet Potato and Mulberry Fruit Juices For Prevention and Treatment of Polyuria(Diuresis) in Kidney diseases

Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years

Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

Imaging of long term intake of delicious smoothies loved by many with the power of reduced risk and treatment of chronic illness with no one mentions about. In fact, it happens. Epidemiological studies with strong evidences suggested that blueberry oral administration hold a potential with therapeutic values for reduced risk of women who carry the mutation gene and treatment of breast cancer(*).

The curable smoothies are collection of recipes produced from natural sources, including organic fruits and vegetables, and some herbs which have been proven effectively for reduced risk and treatment for diseases and syndromes by scientific research of clinical trials and/or studies.

The finding of foods from natural sources has been a dream of scientists and scholars since ancient time. Socrates Said," Let foods be your medicine and let medicine be your foods". Let all of us all exercise the values of the past wisdom to build a letter living and living health while enjoining these delicious drinks.

The smoothie for Prevention and treatment of Polyuria

Yield: 2 servings (about 8 ounces each)
1 1/2 cups sweet potato
1 cup mulberry fruit juice

1. Place all ingredients in a blender and puree about 1 minute
2. Blend on high speed about 1 minute or until the mixture is thick and the ice is well crushed. Add more green tea drink if needed
3. Serve immediately

Recent studies by some renowned institutions suggested that green tea(1) and grape may be the next generation of ingredient extracted from natural sources for reduced risk and treatment of Diuresis.
Polyuria is a condition of passing out too much urine not caused by increased liquid intake.

According to Second Hospital of Lanzhou University, in patients with diabetes, polyuria and hyperglycemia may induce bladder hypertrophy and late stage diabetic bladder dysfunction in urinary secretion(1). In fact, Short-term (3-week induction) diabetes- and polyuria-induced functional and morphological alterations of the bladder can mostly be reversed by Insulin treatment reversed in animal model(2).

According to Dr. Beshay E1 and Dr. Carrier S, anidxidant play an important role in reduced oxidative stress in induced apoptotic cells in the diabetic bladder smooth muscle cells cause of polyuria(3).

Vitamin E, a fat soluble found abundantly in sweet potato may be the next ingredient for prevention and treatment of Polyuria(Diuresis) in Kidney disease(4). According to the Osmangazi University Faculty of Medicine, Vitamin E exhibited protective effects on streptozotocin-induced diabetic rats in diabetic urinary bladder dysfunction, through decreased uroepithelial cells of diabetic bladder.apoptosis(4).

Mulberry, is also known as sang shen, used in traditional Chinese medicine for treatment of dizziness, tinnitus, insomnia, premature graying of the hair.... through tonifying blood and yin, native to China,

Cyanidin-3-O-β-D-glucopyranoside (C3G) isolated from mulberry fruit also exhibited protective effects against bladder dysfunction on streptozotocin-induced diabetic rats, according to the The Catholic University of Korea College of Medicine, study(5).

The effectiveness of Cooked Sweet Potato and Mulberry Fruit Juices may serve as cornerstones of pharmaceutical target for further studies in production of a potential medication for prevention and treatment of Polyuria(Diuresis) in Kidney diseases with little or no adverse effects.

People who are at high risk of Polyuria (Diuresis) due to kidney diseases and people with diabetic Polyuria (Diuresis) should drink no more than 4 servings daily, depending to digestive toleration.

Life style and diet pattern change are necessary.

All Forms of Arthritis are Curable

You Can Eliminate Osteoarthritis

By addressing the Underlying Causes through Clinical Trials and Studies

Ovarian Cysts And PCOS Elimination

Holistic System In Existence That Will Show You How To

Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Super foods Library, Eat Yourself Healthy With The Best of the Best Nature Has to Offer

References

(1) Roles of polyuria and hyperglycemia in bladder dysfunction in diabetes by Xiao N1, Wang Z, Huang Y, Daneshgari F, Liu G.(PubMed)

(2) Short-term diabetes- and diuresis-induced alterations of the bladder are mostly reversible in rats by Xiao N1, Huang Y, Kavran M, Elrashidy RA, Liu G.(PubMed)

(3) Oxidative stress plays a role in diabetes-induced bladder dysfunction in a rat model by Beshay E1, Carrier S.(PubMed)

(4) The protective effects of vitamin E on urinary bladder apoptosis and oxidative stress in streptozotocin-induced diabetic rats by Ustuner MC1, Kabay S, Ozden H, Guven G, Yucel M, Olgun EG, Ustuner D, Unal N, Degirmenci I.(PubMed)

(5) Protective effect of cyanidin-3-O-β-D-glucopyranoside fraction from mulberry fruit pigment against oxidative damage in streptozotocin-induced diabetic rat bladder by Ha US1, Bae WJ, Kim SJ, Yoon BI, Jang H, Hong SH, Lee JY, Hwang SY, Kim SW.(PubMed)

Most Common Diseases of elder: Respiratory Pleural disease: Pleural Plaques - Treatment In traditional Chinese medicine perspective

Pleural disease: Pleural Plaques

The pleura is a thin tissue covered by a layer of cells (mesothelial cells) that surrounds the lungs and lines the inside of the chest wall.
Pleural plaques is a medical condition as a result of exposure to asbestos that lead to accumulated plagues within the pleural cavity(a). Many diseases such as pneumonia, breast cancer, and heart failure can affect the pleural space.,therefore, it is often a secondary effect of another disease process.

The Treatment

In traditional Chinese medicine perspective(47)
Bai He Gu Jin Pian, one of many Chinese herb formula used by TCM to nourish lung Yin energy, moisten the lungs, transform phlegm, and stop cough may have a potential in treating lung diseases, including
1. Bai He
Bai He, is also known as Bulbus Lilii. The Sweet, slightly bitter, slightly cold herb has been used in TCM to treat Chronic cough, blood-streaked sputum, difficult to solve chronic low grade fever, insomnia with abundance of dreams, inability to concentrate, restlessness, irritability, etc., by enhancing the function of heart and lung function.
2. Di Huang
a. Sheng di huang
The bitter, sweet, bitter cold herb has been used in TCM as diuretic agent and to enhance heart function (small doses constrict the blood vessels and large doses dilate the blood vessel), decrease blood sugar, etc., as it clears Heat and cools the Blood, nourishes Yin, generates Fluids, cools the Upward-Blazing of Heart Fire, etc., by promoting the functions of heart, kidney, and liver channels.
b. Shu di huang
The bitter, sweet, bitter and warm herb has been used in as diuretic agent and to enhance heart function (small doses constrict the blood vessels and large doses dilate the blood vessel), decrease blood sugar, etc., as it clears Heat and cools the Blood (Sheng) as it nourishes Yin and Blood, tonifies the Essence, strengthens the Marrow, etc., by enhancing the functions of heart, kidney, and liver channels.
3. Mai Men Dong
Mai Dong or Mai Men Dong is also known as Ophiopogon tuber. The sweet and slightly bitter and cold herb has been used in TCM as anti-arrhythmia, Anti shock, anti bacterial agent and improve contraction of heart muscles, and improves toleration of lack of oxygen, protect heart muscle, enhance immune system, lower blood sugar, etc., as it moistens the Lung and Lung-Yin, benefits the Stomach, promotes generation of Body Fluids, clears the Heart, calms restlessness and anxiety, etc., by enhancing the functions of hear, lung and stomach channels.
4. Xuan Shen
Xuan Shen is also known as Figwort Root. The salty, sweet, bitter and cold herb has been used in TCM as anti bacterial, anti inflammatory, sedative, anti-pyretic agent and to lower blood pressure, blood sugar, etc., as it clears Heat, expels toxins, nourishes Yin, etc. by enhancing the functions of kidney, lung and stomach channels.
5. Bei Mu
Bei Mu is also known as Fritillary Bulb. The sweet, bitter and cold herb has been used in TCM as antibiotic and to raise blood pressure, stop cough, , increased blood sugar,etc. as it transforms Phlegm, calms cough; clears Heat, dissolves nodules, etc. by enhancing the functions of heart and lung channels.
6. Jie Geng
Jie geng is also known as Platycodon root. The bitter, acrid neutral herb has been used in TCM to get rid of phlegm, inhibit cough, treat bronchitis and sore throat, etc., by enhancing the function of lung channel.
7. Gan Cao
Gan Cao is also known as Licorice root. The sweet and neutral herb has been used in TCM as anti allergy, anti inflammation, anti ulcer, anti convulsion and to treat stomach weakness, tired and lack of strength, palpitation and short of breath, cough with abundance of phlegm, stomach and solar plexus pain, etc., as it tonifies the Spleen, benefits the Qi, moistens the Lungs, calms cough, deaf or acute pain, by enhancing all 12 channels.
8. Dang Gui
Dang Qui is also known as Angelica Root. The sweet, bitter, acrid and warm herb has been used in TCM to regulate the menses, lower lipids, reduce platelet coagulation and swelling, expel pus, relieve pain, etc/, as it tonifies and moves Blood, calms pain, moistens the Intestines, etc., by enhancing the function of heart, liver and spleen channels.
9. Bai Shao
Bai Shao also known as White Paeony Root, the bitter sour and cool herb has been used in TCM as anti-spastic, anticonvulsant, analgesic, sedative, antipyretic, anti-inflammatory, antibiotic agent and to owers blood pressure, dilates peripheral blood vessels etc., as it nourishes Blood and liver, preserves the Yin, clams pain;, etc., by promoting the function of liver and spleen channels.

All Forms of Arthritis are Curable
You Can Eliminate Osteoarthritis
By addressing the Underlying Causes through Clinical Trials and Studies

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Super foods Library, Eat Yourself Healthy With The Best of the Best Nature Has to Offer

Sources
(47) http://www.activeherb.com/baihe/

Monday, April 4, 2016

Most Common Disease of 50Plus: The Clinical trials and Studies of Musculo-Skeletal disorders(MSDs) - Osteoarthritis: The Do and do not’s list

The tasty Smoothie of Green Tea, Pomegranate and Peanut for Prevention and Treatment of Acute fatty liver of pregnancy (AFLP)

Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post

Nominated for shorty award over last 4 years

Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

The smoothie for prevention and treatment of Acute fatty liver of pregnancy (AFLP)

Yield: 2 servings (about 8 ounces each)

3/4 cup pomegranate juice
1/4 cup peanut
1 cup green tea drink (Make from 4 grams(2 tea bags) of green tea, and a cup of hot water lipped for 5 minutes, and set aside for cooling to room temperature)

1. Place all ingredients in a blender and puree about 1 minute

2. Blend on high speed about 1 minute or until the mixture is thick and the ice is well crushed.

3. Serve immediately

The finding of a natural source for treatment of Acute fatty liver of pregnancy (AFLP) has been running into many obstacles, many ingredients showed initially with promising result in animal studies have not produced same potentials in large sample size and mutli centers human trials.

Acute fatty liver of pregnancy occurs in third trimester or early postpartum period caused by a disordered metabolism of fatty acids by mitochondria in the fetus. It is a rare, potentional fatal disease(1). According to the joint study lead by the University of Texas Medical Branch Galveston, Acute fatty liver of pregnancy may induce the early vitamin K deficiency bleeding in a newborn with risk of morbidity and mortality(2).th

The increased oxidative stress and reduced antioxidants status also were found in women with acute fatty liver of pregnancy (AFLP)(3).

According to the guideline provided by the Patrick Cowie & Ian G Johnston Department of Anaesthetics, Raigmore Hospital,treatment of acute fatty liver of pregnancy is usually supportive and similar to that of other causes of hepatic dysfunction with practice led to improved outcomes for both mother and child.

Recent studies back by well known institutions proposed, Silymarin, Pomegranates juice, and Green Tea may be the next generation of natural ingredients for prevention and treatment of Acute fatty liver of pregnancy (AFLP)

Silymarin, a phytochemical in the class of phenolic acids, found abundantly in peanut is associated to ameliorated the impairment of hepatic function, through its antioxidant, anti-inflammatory, antifibrotic and anti-apoptotic effects(4).

Dr. Surai PF, professors at Eastern European University said, "Silymarin (SM), an extract from the Silybum marianum (milk thistle) plant containing various flavonolignans (with silybin being the major one), has received a tremendous amount of attention over the last decade as a herbal remedy for liver treatment. In many cases, the antioxidant properties of SM are considered to be responsible for its protective actions"(5).

The Nanjing University School of Medicine study insisted, silymarin treatment reduced the effect of pro inflammatory cytokines such as IL-1β, TNF-α levels induced oxidative stress, and activated immunity in modulation of cytokine and nitric oxide production,...(6).

Pomegranates is a fruit-bearing small tree, genus Punica, belonging to family Lythraceae, native to Iran but has been cultivated in Asian since ancient time. According to the Alexandria University, pomegranate juice (PJ) expressed liver dysfunction protective efects on hepatic antioxidant enzyme activities, lipid peroxidation, DNA fragmentation (DNAF), and caspase-3 activity(7).

Punicalagin (PU), the major ellagitannins found in the pomegranate (Punica granatum) significantly inhibited high fat diet-induced hyperlipidemia and hepatic lipid deposition due to liver mitochondrial dysfunction, by ameliorated the increased expression of pro-inflammatory cytokines(8).

Green tea has been a precious drink in traditional Chinese culture and used exceptional in socialization for more than 4000 thousand years. Because of their health benefits, they have been cultivated for commercial purposes all over the world. According to the University of Sfax, oral administration of green tea, along with cadmium significantly (p < 0.05) improves cadmium-induced liver dysfunction and stress oxidant in rats' liver(9).Dr. Cai X and colleagues at the joint study lea by the Hyogo College of Medicine, suggested, Pu-erh tea, made from the leaves of Camellia sinensis ameliorates hepatic lipid metabolism, inflammation, and insulin resistance in mice with high fat diet(HFD)-induced NASH, presumably by modulating hepatic IL-6/STAT3(the proinflammatory) signaling(10).

Taking altogether, the combination of Green Tea and Orange may process the activities in prevention and treatment of Gallstones

Women who are at higher risk of acute fatty liver of pregnancy (AFLP), due to family history, dietary pattern, obesity,... .... should drink 1 serving daily and women with acute fatty liver of pregnancy (AFLP) should drink as much as they can, depending to digestive toleration.
Life style and diet pattern changed are recommended

All Forms of Arthritis are Curable
You Can Eliminate Osteoarthritis
By addressing the Underlying Causes through Clinical Trials and Studies

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Super foods Library, Eat Yourself Healthy With The Best of the Best Nature Has to Offer

References
(1) [Acute fatty liver of pregnancy (AFLP)--case report].[Article in Czech] by Kacerovský M1, Hossner P.(PubMe)
(2) Early Vitamin K Deficiency Bleeding in a Neonate Associated with Maternal Acute Fatty Liver of Pregnancy by Arya S1, Richardson CJ2, Jain S2, Swischuck LE3.(PubMed)
(3) Liver injury in acute fatty liver of pregnancy: possible link to placental mitochondrial dysfunction and oxidative stress. by Natarajan SK1, Thangaraj KR, Eapen CE, Ramachandran A, Mukhopadhya A, Mathai M, Seshadri L, Peedikayil A, Ramakrishna B,Balasubramanian KA.(PubMed)
(4) Antioxidant, anti-inflammatory and hepatoprotective effects of silymarin on hepatic dysfunction induced by sodium nitrite by Sherif IO1, Al-Gayyar MM.(PubMed)
(5) Silymarin as a Natural Antioxidant: An Overview of the Current Evidence and Perspectives. by Surai PF1,2,3,4.(PubMed)
(6) Silymarin alleviates hepatic oxidative stress and protects against metabolic disorders in high-fat diet-fed mice by Feng B1, Meng R1, Huang B1, Shen S1, Bi Y1, Zhu D1.(PubMed)
(7)Effect of Punica granatum (pomegranate) juice extract on healthy liver and hepatotoxicity induced by diethylnitrosamine and phenobarbital in male rats by Shaban NZ1, El-Kersh MA, Bader-Eldin MM, Kato SA, Hamoda AF.(PubMed)
(8)Mitochondrial dysfunction in obesity-associated nonalcoholic fatty liver disease: the protective effects of pomegranate with its active component punicalagin by Zou X1, Yan C, Shi Y, Cao K, Xu J, Wang X, Chen C, Luo C, Li Y, Gao J, Pang W, Zhao J, Zhao F, Li H, Zheng A, Sun W, Long J, Szeto IM, Zhao Y, Dong Z,Zhang P, Wang J, Lu W, Zhang Y, Liu J, Feng Z.(PubMed)
(9) Positive effects of green tea on hepatic dysfunction, lipid peroxidation and antioxidant defence depletion induced by cadmium by Hamden K1, Carreau S, Marki FA, Masmoudi H, El Feki A.(PubMed)
(10) Pu-erh tea extract ameliorates high-fat diet-induced nonalcoholic steatohepatitis and insulin resistance by modulating hepatic IL-6/STAT3 signaling in mice by Cai X1,2,3, Fang C2,4, Hayashi S2,3, Hao S5, Zhao M6, Tsutsui H2,3, Nishiguchi S7, Sheng J8.(PubMed)

Most Common Diseases of elder: Respiratory Pleural disease: Pleural Plaques - Treatment in Conventional and Alternative Medicine

In conventional medicine perspective
There is no treatment even if you are diagnosed with pleural plague but no symptoms as you can live with them without having any long-term problems with your health. According to the British Lung foundation, If you have pleural plaques, it does not mean that:you will go on to get a more serious disease or you have a more serious disease at the moment; or you are likely to get a serious disease in the future(38).
But you smokes and have exposed to asbestos, you are advised to quit, as smoking are associated with increased risk to develop pleural and other diseases(39).

In Alternative medicine perspective
The following herbs which have been proving to enhance lung function and treat many types of lung diseases may be potential in treating pleural plague
1. Coltsfoot
Coltsfoot (Tussilago farfara) is a perennial herbaceous plant, genus Tussilago, belonging to the family Asteraceae, native to Europe and Asia. The herb has been used over thousands of year to treat asthma, various coughs, bronchial congestion, respiratory disorders, headaches and obstruction in the nasal passage, etc.
a. Antioxidant activity
In the investigation of antioxidant capacities of 56 selected Chinese medicinal plants were evaluated using the Trolox equivalent antioxidant capacity (TEAC) and ferric reducing antioxidant power (FRAP) assays found that that the antioxidants in Dioscorea bulbifera, Eriobotrya japonica, Tussilago farfara and Ephedra sinica possess free radical scavenging activity and oxidant reducing power, and the high positive correlation between antioxidant capacities and total phenolic content, according to the study of “Total phenolic contents and antioxidant capacities of selected chinese medicinal plants” by Song FL, Gan RY, Zhang Y, Xiao Q, Kuang L, Li HB.(40)
b. Anti-inflammatory effect
In the evaluation of Tussilagone (TSL), isolated from the flower of buds of Tussilago farfara (Compositae), is a sesquiterpenoid that is known to exert a variety of pharmacological activities. found that TSL exerts anti-inflammatory activities in murine macrophages by inducing heme oxygenase-1 (HO-1) expression, according to the study of “The anti-inflammatory effect of tussilagone, from Tussilago farfara, is mediated by the induction of heme oxygenase-1 in murine macrophages” by Hwangbo C, Lee HS, Park J, Choe J, Lee JH.(41)
c. Immune system
In the observation of polysaccharides from coltsfoot, sweet flag, clover, Artemisia, marigold, and elecampane and their effects in IgE- and G1 dependent diseases found that induction of anaphylactic shock. In addition, injection of these substances reduced serum concentrations of IgE and IgG1. These substances can be regarded as promising agents for the treatment of IgE-dependent diseases (atopic dermatitis, asthma, atopic rhinitis, urticaria, food allergies, etc.), according to the study of “Effects of plant water-soluble polysaccharides on the production of immunoglobulins E and G1 by lymphocytes of mice sensitized with ovalbumin” by Danilets MG, Belska NV, Bel’sky YP, Uchasova EG, Trophimova ES, Ligatcheva AA, Guriev AM, Belousov MV, Ahmedganov RR, Usubov MS, Agaphonov VI.(42).

2. Mullein
Mullein is hairy biennial plant, genus Verbascum, belonging to Scrophulariaceae, native to Europe, northern Africa and Asia. The herb has been used in traditional medicine over thousands of year as analgesic, antihistaminic, anti-inflammatory, anticancer, antioxidant, antiviral, bacteristat, cardio-depressant, estrogenic, sedative medicine and to treat cough, whooping cough, tuberculosis, bronchitis, hoarseness, pneumonia, earaches, colds, chills, flu, etc.
In the evaluation of Verbascum thapsus commonly known as ‘mullein’ is part of a large family of Scrophulariaceae consisting of more than 360 species and theirs anti inflammatory effects
found that a significant decrease of the expression and activity of iNOS, extracellular O(2) (-) production, SOD, CAT and GPx activity when the cells were treated with verbascoside. Based on these results it is hypothesized that verbascoside has antiinflammatory properties since it reduces the production of superoxide radicals and consequently reduces the activity of iNOS, according to “Antiinflammatory effects in THP-1 cells treated with verbascoside” by
Speranza L, Franceschelli S, Pesce M, Reale M, Menghini L, Vinciguerra I, De Lutiis MA, Felaco M, Grilli A.(43).

3. Cayenne
Cayenne is also known as Cayenne Pepper, a red, hot chili pepper, belonging to Capsicum annuum, the family Solanaceae, native to sub-tropical and tropical regions. It has been used in traditional medicine to increases metabolism, enhance circulatory system and stomach and the intestinal tract, adjust blood pressure, lower LDL cholesterol and triglycerides, treat frostbite, muscles, arthritis, rheumatism, low back pain, strains, sprains, bruises and neuralgia, etc.
a. Antioxidants
C. annuum var. cerasiferum has showed a significant antioxidant activity evaluated by the β-carotene bleaching test (IC(50) of 3.1 μg/ml). The lipophilic fraction of both C. annuum var. acuminatum and C. annuum var. cerasiferum exhibited an interesting and selective inhibitory activity against α-amylase (IC(50) of 6.9 and 20.1 μg/ml, respectively), according to the study of “Comparative study on the chemical composition, antioxidant properties and hypoglycaemic activities of two Capsicum annuum L. cultivars (Acuminatum small and Cerasiferum)’ by Tundis R, Loizzo MR, Menichini F, Bonesi M, Conforti F, Statti G, De Luca D, de Cindio B, Menichini F.(44)
b. Airway Inflammation
Methanolic C. annuum L. extract (CAE) has attenuated ovalbumin-induced increases in NF-κB activity in lungs. Collectively, these results suggest that CAE may be an effective oral treatment for allergic airway inflammation by virtue of its antioxidant activity, according to the study of “Capsicum annuum L. Methanolic Extract Inhibits Ovalbumin-Induced Airway Inflammation and Oxidative Stress in a Mouse Model of Asthma” by Jang HY, Kim SM, Yuk JE, Kwon OK, Oh SR, Lee HK, Jeong H, Ahn KS.(45)
cv. Anti inflammatory Effects
C. baccatum juice has significantly decreased leucocyte and neutrophil migration, exudate volume and protein and LDH concentration in pleural exudates of a pleurisy model and inhibited neutrophil migration and reduced the vascular permeability on carrageenan-induced peritonitis, according to the study of “Anti-inflammatory effects of red pepper (Capsicum baccatum) on carrageenan- and antigen-induced inflammation’ by Spiller F, Alves MK, Vieira SM, Carvalho TA, Leite CE, Lunardelli A, Poloni JA, Cunha FQ, de Oliveira JR.(46).

All Forms of Arthritis are Curable
You Can Eliminate Osteoarthritis
By addressing the Underlying Causes through Clinical Trials and Studies

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Super foods Library, Eat Yourself Healthy With The Best of the Best Nature Has to Offer

Sources
(38) http://www.blf.org.uk/Conditions/Detail/Pleural-plaques
(39) http://www.ncbi.nlm.nih.gov/pubmed/7241256
(40) http://www.ncbi.nlm.nih.gov/pubmed/20640157
(41) http://www.ncbi.nlm.nih.gov/pubmed/19800419
(42) http://www.ncbi.nlm.nih.gov/pubmed/19526097
(43) http://www.ncbi.nlm.nih.gov/pubmed/20812283
(44) http://www.ncbi.nlm.nih.gov/pubmed/21792679
(45) http://www.ncbi.nlm.nih.gov/pubmed/21875363
(46) http://www.ncbi.nlm.nih.gov/pubmed/18380920