Wednesday, April 13, 2016

The Smoothie of Brazil Nut, Tomato and Green Tea In reduced Risk and Treatment of Human immunodeficiency virus (HIV) /Acquired immunodeficiency syndrome (AIDS)

Kyle J. Norton(Scholar, master of Nutrients, all right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

The smoothie for Reduced risk and Treatment of  Acquired immunodeficiency syndrome (AIDS)
Yield: 2 serving (about 8 ounce each)
1 cup Tomato
1/2 cup Brazil nut
1 cup green tea drink (Make from 4 grams of green tea, a slice of ginger and a cup of hot water lipped for 5 minute. Set aside for cooling to room temperature)
1. Place all ingredients in a blender and puree about 1 minute
2. Blend on high speed about 1 minute or until the mixture is thick and the ice is well crushed. Add more green tea drink if needed
3. Serve immediately


The dream of finding the natural ingredient for prevention and treatment of Acquired immunodeficiency syndrome (AIDS), without adverse effects in replacement of conventional medication has not been abated. Some ingredients have to discard because of not achieving the same potent results in human trials.
Scientist community may have found the smoothie(combined ingredients of garlic, olive and coconut oils) with potential and therapeutic value for reduced risk and treatment of Acquired immunodeficiency syndrome (AIDS)without adverse effects.

Human immunodeficiency virus (HIV) is a lentivirus that causes acquired immunodeficiency syndrome (AIDS) of which can lead to the progression of weakened immune system casues of infectous diseases and cancers. According to the studies, patients with human immunodeficiency virus (HIV) are asscoiated to low levels of vitamin A and selenium(1).
Selenium, a chemical element with symbol Se and antioxidant found in Brazil nut, plays an important role in protection of cell against significant impairments of antioxidative defenses induced human immunodeficiency virus (HIV) (2).
Dr. Delmas-Beauvieux MC and colleagues at the Université Bordeaux II, suggested, selenium supplementation could be of great interest in protecting cells against oxidative stress and glutathione peroxidase (GPX), and glutathione (GSH) are important in expression of natural enzymatic defense system in detoxifying hydrogen peroxide(3).

Vitamin A, a bi-polar molecule formed by bonds between carbon and hydrogen, is a fat soluble vitamin converted from beta-carotene, a powerful antioxidant. Accoridng to the The University of Maryland School of Medicine, deficiency of vitamin A in human immunodeficiency virus (HIV) infection has been associated with more progressive HIV disease(4).
Dr.Mehta S and Dr. Fawzi W. in the study of the effects of vitamins, including vitamin A, on HIV/AIDS patients, said, "periodic vitamin A supplementation of HIV-infected infants and children is beneficial in reducing all-cause mortality and morbidity and is recommended"(5).

Green tea has been a precious drink in traditional Chinese culture and used exceptional in socialization for more than 4000 thousand years. Due to its commercial values and health effects, green tea now has been cultivated all over the world in suitable climate.
According to the Creighton University, green tea, epigallocatechin gallate, theaflavins may be effective in prevention and treatment of sexually transmitted infections caused by HIV (human immunodeficiency virus), HSV (herpes simplex virus) and HPV (human papilloma virus)(6).

Dr. Hamza A and Dr. Zhan CG. said, "(-)-epigallocatechin gallate (EGCG) from green tea is an inhibitor blocking gp120-CD4 binding" by blocking the initial step of HIV-1 entry into the cells"(7).
In support of above blocking, Dr. Williamson MP and colleagues at the University of Sheffield suggested, green tea Epigallocatechin gallate has a potential use as adjunctive therapy in HIV-1 infection(8) through its binding of HIV-1 glycoprotein (gp) 120 to the CD4 molecule on T cells.

The Smoothie of Brazil Nut, Tomato and Green Tea  may hold a key for further studies in production of a curable natural remedy for prevention and treatment of  Human immunodeficiency virus (HIV) /Acquired immunodeficiency syndrome (AIDS)
.
People who are at  increased risk of Human immunodeficiency virus (HIV) /Acquired immunodeficiency syndrome (AIDS) due to family history, weaken immunity,....should drink at least one cup or more daily. People with hHuman immunodeficiency virus (HIV) /Acquired immunodeficiency syndrome (AIDS) may drink as much as they can, depending to the digestive toleration.

References
(1) The enzymatic antioxidant system in blood and glutathione status in human immunodeficiency virus (HIV)-infected patients: effects of supplementation with selenium or beta-carotene by Delmas-Beauvieux MC1, Peuchant E, Couchouron A, Constans J, Sergeant C, Simonoff M, Pellegrin JL, Leng B, Conri C, Clerc M.(PubMed)
(2) Effect of selenium supplementation on CD4+ T-cell recovery, viral suppression and morbidity of HIV-infected patients in Rwanda: a randomized controlled trial by Kamwesiga J1, Mutabazi V, Kayumba J, Tayari JC, Uwimbabazi JC, Batanage G, Uwera G, Baziruwiha M, Ntizimira C, Murebwayire A, Haguma JP,Nyiransabimana J, Nzabandora JB, Nzamwita P, Mukazayire E; Rwanda Selenium Authorship Group.(PubMed)
(3) Plasma Selenium Concentrations Are Sufficient and Associated with Protease Inhibitor Use in Treated HIV-Infected Adults by Hileman CO1, Dirajlal-Fargo S2, Lam SK3, Kumar J3, Lacher C4, Combs GF Jr4, McComsey GA5.(PubMed)
(4) Quantitation of parvalbumin+ neurons and human immunodeficiency virus type 1 (HIV-1) regulatory gene expression in the HIV-1 transgenic rat: effects of vitamin A deficiency and morphine by Sultana S1, Li H, Puche A, Jones O, Bryant JL, Royal W.(PubMed)
(5) Effects of vitamins, including vitamin A, on HIV/AIDS patients by Mehta S1, Fawzi W.(PubMed)
(6) Natural polyphenols: potential in the prevention of sexually transmitted viral infections by Date AA1, Destache CJ2.(PubMed)
(7) How can (-)-epigallocatechin gallate from green tea prevent HIV-1 infection? Mechanistic insights from computational modeling and the implication for rational design of anti-HIV-1 entry inhibitors by Hamza A1, Zhan CG.(PubMed)
(8) Epigallocatechin gallate, the main polyphenol in green tea, binds to the T-cell receptor, CD4: Potential for HIV-1 therapy. by Williamson MP1, McCormick TG, Nance CL, Shearer WT.(PubMed)

Most Common Diseases of 50plus: Pulmonary vascular disease(Respiratory disease): Pulmonary edema- The Phytochemicals

Kyle J. Norton(Scholar and Master of Nutrients, all right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

                           Respiratory Disease

Respiratory Disease is defined as medical conditions, affecting the breathing organ and tissues including Inflammatory lung disease, Obstructive lung diseases, Restrictive lung diseases, Respiratory tract infections, trachea, bronchi, bronchioles, alveoli, the nerves and muscles breathing, etc,.

         Pulmonary vascular disease:  Pulmonary edema


Pulmonary vascular disease is defined as a condition of blood flow to the lung’s artery is blocked suddenly due to a blood clot somewhere in the body, including pulmonary embolism, chronic thromboembolic disease, pulmonary arterial hypertension, pulmonary veno-occlusive disease, pulmonary arteriovenous malformations, pulmonary edema, etc.
                                                   
Pulmonary edema is defined as a condition of fluid accumulation in the air spaces and parenchyma of the lungs of that can lead to difficult of breathing and respiratory failure.


                           The Prevention


B. Phytochemicals to prevent Pulmonary edema
1. Resveratrol
Resveratrol is a phytochemical in the class of Stilbenoids, found abundantly in skins and seed of grape wine, nuts, peanuts, etc.
a. Cardiovascular diseasesIn the revie of reviews some of the key studies, and the known mechanisms for these beneficial effects. Evidence from different experimental studies, including from the authors’ laboratories, and the beneficial effects of polyphenols found in red wine, especially resveratrol in grape skins.
found that Resveratrol benefits include a reduction in cardiovascular morbidity and mortality, lung cancer and prostate cancer by approximately 30% to 50%, 57% and 50%, respectively. Polyphenols possess antioxidant, superoxide-scavenging, ischemic-preconditioning and angiogenic properties. Some of these properties of polyphenols may explain their protective effects on the cardiovascular system, as well as other body organs, according to “Significance of wine and resveratrol in cardiovascular disease: French paradox revisited” by Vidavalur R, Otani H, Singal PK, Maulik N.(50).
b. Cardiovascular health
In the review of Resveratrol (3,4′,5-trihydroxystilbene), a member of natural, plant-derived chemicals known as polyphenols and is attracting increased attention due to its diverse health benefits especially in case of cardiovascular disease, cancer, diabetes and neurological problems, indicated that Recently, resveratrol was found to induce autophagy and regenerate myocardial ischemic tissue treated with stem cells. Overall observation indicates that resveratrol has a high therapeutic potentials for the treatment of cardiovascular diseases, according to “Resveratrol and cardiovascular health” by Das M, Das DK.(51).
2. Phytosterols Phytosterols are a subgroup of lipids, the steroid compounds similar to cholesterol in plant, Researchers have found more than 200 of them.
1. Cholesterol
Phytosterols are best best known to have a property in lowering the blood cholesterol, according to the study of ” Scientific Opinion on the substantiation of health claims related to plant sterols and plant stanols and maintenance of normal blood cholesterol concentrations (ID 549, 550, 567, 713, 1234, 1235, 1466, 1634, 1984, 2909, 3140), and maintenance of normal prostate size and normal urination (ID 714, 1467, 1635) pursuant to Article 13(1) of Regulation (EC) No 1924/2006″, posted in EFSA Journak, researchers filed in summary that a cause and effect relationship has been established between the consumption of plant sterols and plant stanols and the reduction of blood cholesterol concentrations.
2. Coronary heart disease
In most case, if a substance have a good effect in lowering blood cholesterol concentration, it may also promote heart health. In a study of ” Plant Sterols and Blood Cholesterol Scientific substantiation of a health claim related to plant sterols and lower/reduced blood cholesterol and reduced risk of (coronary) heart disease pursuant to Article 14 of Regulation (EC) No 1924/20061″ from Scientific Opinion of the Panel on Dietetic Products, Nutrition and Allergies Adopted on 11 July 2008, researchers indicated that Elevated low-density lipoprotein (LDL) blood cholesterol is one recognised risk factor for
coronary heart disease (CHD). CHD is an important cause of mortality and morbidity.
Lowering LDL-cholesterol by dietary intervention has been shown to reduce the risk of
coronary heart disease. The Panel considers that the claimed effect of lowering LDLcholesterol
is beneficial to human health.
3. Epigallocatechin
Epigallocatechin, including catechins, is a phytochemical of Flavan-3-ols, in the group of Flavonoids (polyphenols), found abundantly in green tea, St John wort, black Tea, carob flour, Fuji apples, etc.
a Cardiovascular diseases
In the identification of green tea catechins and its lowering the risk of cardiovascular diseases, found that green tea catechins, particularly (-)-epigallocatechin gallate, interfere with the emulsification, digestion, and micellar solubilization of lipids, critical steps involved in the intestinal absorption of dietary fat, cholesterol, and other lipids. Based on the observations, it is likely that green tea or its catechins lower the absorption and tissue accumulation of other lipophilic organic compounds, according to “Green tea as inhibitor of the intestinal absorption of lipids: potential mechanism for its lipid-lowering effect” by Koo SI, Noh SK.(52).
b. Cholesterol
In the examination of the influence of green tea extract, epicatechin (EC), epicatechin galate (ECG) as well as epigallocatechin galate (EGCG) on oxidative modifications of LDL of human blood serum, found that Catechins and green tea abilities to protect lipophilic antioxidant–alpha-tocopherol against oxidation have been also examined. The results reveal that peroxidation of LDL is markedly prevented by green tea extract and in a slightly weaker way by catechins (EGCG in particular), which is manifested by a decrease in concentration of conjugated dienes, lipid hydroperoxides, MDA, dityrosine and by an increase in tryptophan content, according to “The comparison of effect of catechins and green tea extract on oxidative modification of LDL in vitro” by Ostrowska J, Skrzydlewska E.(53).

Most Common Disease of50plus: The Clinical trials and Studies of Musculo-Skeletal disorders(MSDs) - Osteoarthritis: Treatment In herbal and traditional Chinese medicine - The Fabulous Olive

Kyle J. Norton (Scholar)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

Musculoskeletal disorders (MSDs) are medical condition mostly caused by work related occupations and working environment, affecting patients’ muscles, joints, tendons, ligaments and nerves and developing over time. A community sample of 73 females and 32 males aged 85 and over underwent a standardised examination at home. Musculoskeletal pain was reported by 57% of those interviewed. A major restriction of joint movement range was frequent in the shoulder but uncommon in other joints(1).

Types of Musculo-Skeletal disorders in elder(2)

1. Osteoarthritis
2. Gout
3. Rheumatoid Arthritis
4. Polymalagia Arthritis
5. Cervical myleopathy and spinal canal stenosis
6. Osteoporosis
7. Low back pain
8. Fibromyalgia



                                                      Osteoarthritis


Osteoarthritis (OA), a form of arthritis, is defined as a condition of as a result of aging causes of wear and tear on a joint, affecting over 25 million people in the United States in alone. University of Porto Medical School indicated that one must understand the differences in prevalence and incidence estimates of osteoarthritis (OA), according to case definition, in knee, hip and hand joints(3).
The characteristics of osteoarthritis are aching pain(5), stiffness(6), or difficulty of moving the joint or joints(7). The pain usually gets worse in change of weather, at night and in the advanced diseases, the pain can occur even at rest(8). Today management of osteoarthritis (OA) focuses on pain relief and improved physical function through pharmacological, non pharmacological, and surgical treatments(4).

                           The Treatment

B. In herbal and traditional Chinese medicine perspective
3. The Incredible Olive
Olive is belongs to the the family Oleaceae, native to the coastal areas of the eastern Mediterranean Basin and south end of the Caspian Sea. Its fruit, is also called the olive and the source of olive oil.

Olive Oil: Fat Content
1. Saturated fats
a. Palmitic acid
b. Stearic acid
c. Arachidic acid
d. ehenic acid
e. Myristic acid
f. Lignoceric acid
2. Unsaturated fat3. Monounsaturated fats
a. Oleic acid
b. Palmitoleic acid
3. Polyunsaturated fats
a. Linoleic acid
b. Linolenic acid

Monounsaturated fatty acids found abundantly in olive oil, may be beneficiary for reduced inflammation(362) and expression of lubricin to preserve the articular cartilage and then the entire joint, in rat model(362), as well as improving the disease associated loss of weight(363), such as osteoarthritis.
In a pilot double-blinded, randomized, clinical trial of topical virgin olive oil versus piroxicam gel in osteoarthritis of the knee, conducted by Ardabil University of Medical Science, researchers showed that the use of olive oil in the experiment is more effective than medical gel for knee osteoarthritis, probably due to its phytochemiocals oleuropein and hydroxy tyroso(364).
Other in the study of fruit and vegetable antioxidants of simple and polyphenols, showed that olive vegetation water (OVW) and its combination with glucosamine exhibit anti inflammatory processes, and may be considered as an effective therapyfor treatment of rheumatoid and osteoarthritis(365).In mechanical inflammatory arthritis (osteoarthritis, OA), The Olive leaf extract (OLE) also inhibit inflammatory process, including ear edema, myeloperoxidase (MPO) production, and may be beneficiary for the treatment of OA in humans(366).


Arthritis Is Curable
You Can Eliminate Osteoarthritis
By addressing the Underlying Causes through Clinical Trials and Studies

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Super foods Library, Eat Yourself Healthy With The Best of the Best Nature Has to Offer recommended by Kyle J. Norton

Back to Kyle J. Norton Home page http://kylejnorton.blogspot.ca


References
(1) Prevalence of rheumatic symptoms, rheumatoid arthritis, ankylosing spondylitis, and gout in Shanghai, China: a COPCORD study by Dai SM1, Han XH, Zhao DB, Shi YQ, Liu Y, Meng JM.(PubMed)
(2) Musculoskeletal Disorders in the Elderly by Ramon Gheno, Juan M. Cepparo, Cristina E. Rosca,1 and Anne Cotten(PMC)
(3) The effect of osteoarthritis definition on prevalence and incidence estimates: a systematic review by Pereira D1, Peleteiro B, Araújo J, Branco J, Santos RA, Ramos E.(PubMed)
(4) Effect of therapeutic aquatic exercise on symptoms and function associated with lower limb osteoarthritis: systematic review with meta-analysis by Waller B1, Ogonowska-Slodownik A2, Vitor M3, Lambeck J4, Daly D5, Kujala UM6, Heinonen A7.(PubMed)
(5) Effects of therapeutic ultrasound on pain, physical functions and safety outcomes in patients with kneeosteoarthritis: A systematic review and meta-analysis by Zhang C1, Xie Y2, Luo X3, Ji Q3, Lu C3, He C4, Wang P3.(PubMed)
(6) Oral intake of purple passion fruit peel extract reduces pain and stiffness and improves physical function in adult patients with knee osteoarthritis by Farid R1, Rezaieyazdi Z, Mirfeizi Z, Hatef MR, Mirheidari M, Mansouri H, Esmaelli H, Bentley G, Lu Y, Foo Y, Watson RR.(PubMed)
(7) Functional ability, mobility, and pain before and after knee replacement in patients aged 75 and older: a cross-sectional study by Limnell K1, Jämsen E, Huhtala H, Jäntti P, Puolakka T, Jylhä M.(PubMed)
(8) The symptoms of OA and the genesis of pain by David J. Hunter, MBBS PhD,1,2 Jason J. McDougall, BSc PhD,3 and Francis J. Keefe4(PubMed)
(362) Extra-virgin olive oil diet and mild physical activity prevent cartilage degeneration in an osteoarthritis model: an in vivo and in vitro study on lubricin expression by Musumeci G, Trovato FM, Pichler K, Weinberg AM, Loreto C, Castrogiovanni P.(PubMed)

(363) Protective effects upon experimental inflammation models of a polyphenol-supplemented virgin olive oil diet by Martínez-Domínguez E1, de la Puerta R, Ruiz-Gutiérrez V.(PubMed)
(364) A pilot double-blinded, randomized, clinical trial of topical virgin olive oil versus piroxicam gel in osteoarthritis of the knee.in Bohlooli S1, Jastan M, Nakhostin-Roohi B, Mohammadi S, Baghaei Z.(PubMed)
(365) Hydrolyzed olive vegetation water in mice has anti-inflammatory activity by Bitler CM1, Viale TM, Damaj B, Crea R.(PubMed)
(366) Mechanisms of olive leaf extract-ameliorated rat arthritis caused by kaolin and carrageenan. by Gong D1, Geng C, Jiang L, Wang L, Yoshimura H, Zhong L.(PubMed)

Most Common Diseases of 50plus: Pulmonary vascular disease(Respiratory disease): Pulmonary edema- The Diets

Kyle J. Norton(Scholar and Master of Nutrients, all right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

                           Respiratory Disease

Respiratory Disease is defined as medical conditions, affecting the breathing organ and tissues including Inflammatory lung disease, Obstructive lung diseases, Restrictive lung diseases, Respiratory tract infections, trachea, bronchi, bronchioles, alveoli, the nerves and muscles breathing, etc,.

         Pulmonary vascular disease:  Pulmonary edema


Pulmonary vascular disease is defined as a condition of blood flow to the lung’s artery is blocked suddenly due to a blood clot somewhere in the body, including pulmonary embolism, chronic thromboembolic disease, pulmonary arterial hypertension, pulmonary veno-occlusive disease, pulmonary arteriovenous malformations, pulmonary edema, etc.
                                                   
Pulmonary edema is defined as a condition of fluid accumulation in the air spaces and parenchyma of the lungs of that can lead to difficult of breathing and respiratory failure.

                        Prevention

A. Diet to prevent Pulmonary edema
Diet to Prevent cardiovascular disease can be helpful to reduce the risk of pulmonary edema
1. Mediterranean diet
In a study of a random sample of Jewish adults, aged 35+ using a 24-h recall questionnaire. A MD score (scale 0-8) computed reflecting high ratio of monounsaturated to saturated fat; high intake of alcohol, legumes, cereals, vegetables, and fruits; low intakes of meat and it’s products, milk and dairy products. Scoring <5 was defined as Low-MD consuming, while 5+ as High-MD consuming, showed that the risk for myocardial infarction, coronary bypass, angioplasty, and any cardiovascular disease in men increased by 1.2 (P = 0.04), 1.6 (P = 0.01), 1.4 (P = 0.003), and 1.3 (P = 0.01), respectively, for each MD score decrease. In women, crude odds ratios ranged from 1.4 to 1.9 but were not statistically significant(29).
2. Wholegrain cereals
In the search of CENTRAL (Issue 4, 2005), MEDLINE (1966 to 2005), EMBASE (1980 to 2005), CINAHL (1982 to 2005), ProQuest Digital Dissertations (2004 to 2005) with no language restrictions applied, found that ten trials met the inclusion criteria. None of the studies found reported the effect of wholegrain diets on CHD mortality or CHD events or morbidity. All 10 included studies reported the effect of wholegrain foods or diets on risk factors for CHD. Studies ranged in duration from 4 to 8 weeks. In eight of the included studies, the wholegrain component was oats. Seven of the eight studies reported lower total and low density lipoproteins (LDL) cholesterol with oatmeal foods than control foods. When the studies were combined in a meta-analysis lower total cholesterol (-0.20 mmol/L, 95% confidence interval (CI) -0.31 to -0.10, P = 0.0001 ) and LDL cholesterol (0.18 mmol/L, 95% CI -0.28 to -0.09, P 150 mg/dl) were treated with 600 mg of SPS (n=15) or placebo (n=15) daily. After 4 weeks, serum TG levels in the SPS-treated group were significantly (P171 g/d, versus Q1, ≤78 g/d; HR, 0.48; 95% CI, 0.29-0.77). Each 25-g/d increase in white fruit and vegetable consumption was associated with a 9% lower risk of stroke (HR, 0.91; 95% CI, 0.85-0.97). Apples and pears were the most commonly consumed white fruit and vegetables (55%), according to “Colors of fruit and vegetables and 10-year incidence of stroke” by Oude Griep LM, Verschuren WM, Kromhout D, Ocké MC, Geleijnse JM.(46)
c. Dietary fiberDaily intake of right amount of fibers can prvent and treata. Diabetes, as Increased consumption of vegetables, whole grains, and soluble and insoluble fiber is associated with improved glucose metabolism in both diabetic and nondiabetic individuals. Improvements in insulin sensitivity and glucose homeostasis were more evident in participants following a plant-based diet compared with other commonly used diets, according to the study of “Efficacy of high-fiber diets in the management of type 2 diabetes mellitus” by Wolfram T, Ismail-Beigi F.(47)
6. Tomato is a red, edible fruit, genus Solanum, belongs to family Solanaceae, native to South America. Because of its health benefits, tomato is grown world wide for commercial purpose
and often in green house.
a. Cardiovascular diseases
In the review of patents and products within the context of lycopene and CVD prevention and health claims indicated that in vitro data and results from animal experiments partly showed promising preventive mechanisms of lycopene. In contrast, until now, human intervention studies mostly failed to show any CVD prevention. However, there is still an encouraging situation, giving hints for antioxidant as well as anti-inflammatory effects of lycopene. These mechanisms could be the background for cardio-protective effects of tomatoes and tomato products, according to “Lycopene and heart health” by Böhm V.(48)
b. Antioxidative and Cancer Cell-Inhibiting Activities
In the research of Tomato ( Solanum lycopersicum ) plants synthesize nutrients, pigments, and bioactive compounds and their benefit in nutrition and human health found that Tomato extracts promoted growth in normal liver (Chang) cells, had little effect in normal lung (Hel299) cells, mildly inhibited growth of lung cancer (A549) cells, and first promoted and then, at higher concentrations, inhibited growth in lymphoma (U937) cells. The relationship of cell growth to measured constituents was not apparent, according to “Free Amino Acid and Phenolic Contents and Antioxidative and Cancer Cell-Inhibiting Activities of Extracts of 11 Greenhouse-Grown Tomato Varieties and 13 Tomato-Based Foods” by Choi SH, Kim HR, Kim HJ, Lee IS, Kozukue N, Levin CE, Friedman M.(49)
7. Etc.

All Forms of Arthritis are Curable
You Can Eliminate Osteoarthritis
By addressing the Underlying Causes through Clinical Trials and Studies

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to General health http://kylejnorton.blogspot.ca/p/general-health.html

Back to Kyle J. Norton Home page http://kylejnorton.blogspot.ca

Sources
(a) http://www.ncbi.nlm.nih.gov/pubmed/19739476 (25) http://www.ncbi.nlm.nih.gov/pubmed/23479070(29) http://www.ncbi.nlm.nih.gov/pubmed/15533543
(30) http://www.ncbi.nlm.nih.gov/pubmed/17443567
(31) http://www.ncbi.nlm.nih.gov/pubmed/12569114
(32) http://www.ncbi.nlm.nih.gov/pubmed/20713332
(33) http://www.ncbi.nlm.nih.gov/pubmed/20728596
(34) http://www.ncbi.nlm.nih.gov/pubmed/20728596
(35) http://www.ncbi.nlm.nih.gov/pubmed/19394473
(36) http://www.ncbi.nlm.nih.gov/pubmed/21339136
(37) http://www.ncbi.nlm.nih.gov/pubmed/20842560
(38) http://www.ncbi.nlm.nih.gov/pubmed/22139893
(39) http://www.ncbi.nlm.nih.gov/pubmed/22136960
(40) http://www.ncbi.nlm.nih.gov/pubmed/18577222
(41) http://www.ncbi.nlm.nih.gov/pubmed/8091840
(42) http://www.ncbi.nlm.nih.gov/pubmed/12951900
(43) http://www.ncbi.nlm.nih.gov/pubmed/22139566
(44) http://www.ncbi.nlm.nih.gov/pubmed/18813866
(45) http://www.ncbi.nlm.nih.gov/pubmed/22164774
(46) http://www.ncbi.nlm.nih.gov/pubmed/21921279
(47) http://www.ncbi.nlm.nih.gov/pubmed/20713332
(48) http://www.ncbi.nlm.nih.gov/pubmed/22076972
(49) http://www.ncbi.nlm.nih.gov/pubmed/22070764

The Delicious of Green Tea, Coffee and Orange for Prevention and Treatment of Gallstones

Kyle J. Norton(Scholar, Master of Nutrients), all right reserved.
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

The smoothie for prevention and treatment of Gallstones

Yield: 2 serving (about 8 ounce each)
1/2 cup cooked fennel
1 large slice of ginger
1/4 cup of celery
1 1/2 cups of almond milk

1. Place all ingredients in a blender and puree about 1 minute
2. Blend on high speed about 1 minute or until the mixture is thick and the ice is well crushed.
3. Serve immediately

The finding of a natural source for reduced risk and treatment of Gallstones has encountered many obstacles, many ingredients showed initially the promising result in animal studies have not produced same potentials in either large sample size and mutli centers human trials.

Recent study from some well known institutions suggested that combination of Green Tea(1) and fennel(4) and celery(8) may hold a key for a natural ingredients for reduced painful symptoms and treatment of Gallstones.

Gallstones are crystalline concretion, hard, pebble-like deposits formed in side the gallbladder, resulting in obstruction of the biliary tree which can lead to infection of the bile ducts with symptoms of constant pain, biliary coli, etc.  According to the Royal Infirmary, patients with human cholesterol gallstones are found to associate to lower intake of lower amounts of 10 among 16 antioxidants (P < 0.05 for methionine, alpha-tocopherol, manganese, and vitamin D; 0.05 < P < 0.10 for cysteine, beta-carotene, vitamin C, selenium, zinc, and phosphorus)(1).

Green tea has been a precious drink in traditional Chinese culture and used exceptional in socialization for more than 4000 thousand years. Due to its commercial values and health effects, green tea now has been cultivated all over the world in suitable climate. Study from Chinese study suggested, tea consumption may decrease the risk of cancers of the gallbladder and gallstone disease among females(2).
Dr. Zhang XH and research team at the Shanghai Cancer Institute, in a 627 incident cases with biliary tract cancer, 1,037 cases with biliary stones and 959 randomly selected controls said, " consumed at least 1 cup of tea per day for at least 6 month,.... had significantly reduced risks of biliary stones"(3).

Coffee, a brewed drink prepared from roasted coffee beans from the Coffee plant may also processed anti Gallstones effects depending to increased intake of coffee drink daily(4).

Vitamin C, also known as L-ascorbate, is a water soluble vitamin with a chemical structure formula of C6H6O6 found in orange inhibited the risk of gallstone formation without changing plasma lipids and bile lipid concentration(5).
In an observational, population-based study of 2129 subjects aged 18-65 years randomly selected from the general population in southern German with a prevalence of gallstones of 7.8% (167/2129) expressed the regular intake of vitamin C and to a lesser extent, reduced cholesterol levels in association of risk of gallstones(6).
In support to the influence of vitamin C supplementation in conditions for cholesterol gallstone formation in humans, the Danderyd Hospital, reported a significant change of relative concentration of phospholipids, bile acid composition, and percentage of cholic acid and those of deoxycholic acid, ursodeoxycholic acid and lithocholic acid in vitamin C treatment group in comparison to control(7).

The Smoothie of  Green Tea, Coffee and Orangemay hold a key for further studies in production of a curable natural remedy for prevention and treatment of  Gallstones.
.
People who are at  increased risk of Gallstones, due to family history, overweight, smoking....should drink at least one cup or more daily. People with Gallstones may drink as much as they can, depending to the digestive toleration.

References
(1) A pilot study of antioxidant intake in patients with cholesterol gallstones by Worthington HV1, Hunt LP, McCloy RF, Maclennan I, Braganza JM.(PubMed)
(2) [Tea consumption and risk of biliary tract cancers and gallstone disease: a population-based case-control study in Shanghai, China].[Article in Chinese] by Zhang XH1, Gao YT, Rashid A, Deng J, Liu EJ, Wu K, Sun L, Cheng JR, Gridley G, Hsing AW.(PubMed)
(3) Tea drinking and the risk of biliary tract cancers and biliary stones: a population-based case-control study in Shanghai, China by Zhang XH1, Andreotti G, Gao YT, Deng J, Liu E, Rashid A, Wu K, Sun L, Sakoda LC, Cheng JR, Shen MC, Wang BS, Han TQ, Zhang BH, Gridley G, Fraumeni JF Jr, Hsing AW.(PubMed)
(4) Association of coffee consumption with gallbladder disease by Ruhl CE1, Everhart JE.(PubMed)
(5) [Effects of vitamin C administration on cholesterol gallstone formation].[Article in Spanish] by del Pozo R, Muñoz M, Dumas A, Tapia C, Muñoz K, Fuentes F, Maldonado M, Jüngst D.(PubMed)
(6) Vitamin C supplement use may protect against gallstones: an observational study on a randomly selected population by Walcher T1, Haenle MM, Kron M, Hay B, Mason RA, Walcher D, Steinbach G, Kern P, Piechotowski I, Adler G, Boehm BO, Koenig W, Kratzer W; EMIL study group.(PubMed)
(7) The effect of vitamin C in high doses on plasma and biliary lipid composition in patients with cholesterolgallstones: prolongation of the nucleation time by Gustafsson U1, Wang FH, Axelson M, Kallner A, Sahlin S, Einarsson K.(PubMed)

Tuesday, April 12, 2016

Most Common Disease of50plus: The Clinical trials and Studies of Musculo-Skeletal disorders(MSDs) - Osteoarthritis: Treatment In herbal and traditional Chinese medicine - The Fabulous Salmon

Kyle J. Norton (Scholar)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

Musculoskeletal disorders (MSDs) are medical condition mostly caused by work related occupations and working environment, affecting patients’ muscles, joints, tendons, ligaments and nerves and developing over time. A community sample of 73 females and 32 males aged 85 and over underwent a standardised examination at home. Musculoskeletal pain was reported by 57% of those interviewed. A major restriction of joint movement range was frequent in the shoulder but uncommon in other joints(1).

Types of Musculo-Skeletal disorders in elder(2)

1. Osteoarthritis
2. Gout
3. Rheumatoid Arthritis
4. Polymalagia Arthritis
5. Cervical myleopathy and spinal canal stenosis
6. Osteoporosis
7. Low back pain
8. Fibromyalgia



                                                      Osteoarthritis


Osteoarthritis (OA), a form of arthritis, is defined as a condition of as a result of aging causes of wear and tear on a joint, affecting over 25 million people in the United States in alone. University of Porto Medical School indicated that one must understand the differences in prevalence and incidence estimates of osteoarthritis (OA), according to case definition, in knee, hip and hand joints(3).
The characteristics of osteoarthritis are aching pain(5), stiffness(6), or difficulty of moving the joint or joints(7). The pain usually gets worse in change of weather, at night and in the advanced diseases, the pain can occur even at rest(8). Today management of osteoarthritis (OA) focuses on pain relief and improved physical function through pharmacological, non pharmacological, and surgical treatments(4).

                           The Treatment

B. In herbal and traditional Chinese medicine perspective
2. The Fabulous Salmon
Salmon is the common name for Salmonidae. They are anadromous, born in fresh water, migrate to the ocean, then travel thousands of miles in the deep sea cold water throughout their life cycle and within to five years returning to the exacted location where they were born to reproduce and die.

Nutrients
1. Protein
2. Omega-3 fatty acids
3. B vitamins
4. Vitamin D
5. Astaxanthin
is a potent antioxidant that stimulates the development of healthy fish nervous systems and enhances the fish's fertility and growth rate.
6. Selenium
7. Tryptophan
8. Magnesium
9. Phosphorus
10. Etc.

Intake of salmon calcitonin, a hormone produced by the thyroid gland of salmon or a synthetic polypeptide of the same sequence found in salmon(360) has shown to reduce OA pathogenesis and bone resorption, according to the study of 10 7-month-old female Sprague Dawley rat model by Nordic Bioscience A/S at Danmark(354) and counteract of type II collagen (CII), degradation and related surface erosions of articular cartilage in ovariectomized rat model(355), probably through the effects of subchondral trabecular bone changes and on osteoarthritic cartilage lesions(356). The change of both markers of bone and cartilage degradation in osteoarthritis has made salmon calitonin a potential new treatment opportunities for OA(358).
In treatment of symptomatic knee osteoarthritis, intake of salmon calcitonin showed an effect on sum of pain, function, stiffness, and total scores, the biomarkers of bone and joint metabolism but not in patients with symptomatic knee OA(357), according to 2 phase of 3 trials study by Nordic Bioscience, Denmark.
According to the Université Catholique de Louvain, oral salmon calcitonin, also improved functional disability and reduced levels of biomarkers of which can predict of joint space narrowing induced cartilage loss(359).
The high amount of Omega 3 fatty acid also make salmon of the dietary nutrients for the modulation of inflammation and metabolic health including prevention reduced risk of progression of osteoarthritis(361).

Arthritis Is Curable
You Can Eliminate Osteoarthritis
By addressing the Underlying Causes through Clinical Trials and Studies

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Super foods Library, Eat Yourself Healthy With The Best of the Best Nature Has to Offer recommended by Kyle J. Norton

Back to Kyle J. Norton Home page http://kylejnorton.blogspot.ca


References
(1) Prevalence of rheumatic symptoms, rheumatoid arthritis, ankylosing spondylitis, and gout in Shanghai, China: a COPCORD study by Dai SM1, Han XH, Zhao DB, Shi YQ, Liu Y, Meng JM.(PubMed)
(2) Musculoskeletal Disorders in the Elderly by Ramon Gheno, Juan M. Cepparo, Cristina E. Rosca,1 and Anne Cotten(PMC)
(3) The effect of osteoarthritis definition on prevalence and incidence estimates: a systematic review by Pereira D1, Peleteiro B, Araújo J, Branco J, Santos RA, Ramos E.(PubMed)
(4) Effect of therapeutic aquatic exercise on symptoms and function associated with lower limb osteoarthritis: systematic review with meta-analysis by Waller B1, Ogonowska-Slodownik A2, Vitor M3, Lambeck J4, Daly D5, Kujala UM6, Heinonen A7.(PubMed)
(5) Effects of therapeutic ultrasound on pain, physical functions and safety outcomes in patients with kneeosteoarthritis: A systematic review and meta-analysis by Zhang C1, Xie Y2, Luo X3, Ji Q3, Lu C3, He C4, Wang P3.(PubMed)
(6) Oral intake of purple passion fruit peel extract reduces pain and stiffness and improves physical function in adult patients with knee osteoarthritis by Farid R1, Rezaieyazdi Z, Mirfeizi Z, Hatef MR, Mirheidari M, Mansouri H, Esmaelli H, Bentley G, Lu Y, Foo Y, Watson RR.(PubMed)
(7) Functional ability, mobility, and pain before and after knee replacement in patients aged 75 and older: a cross-sectional study by Limnell K1, Jämsen E, Huhtala H, Jäntti P, Puolakka T, Jylhä M.(PubMed)
(8) The symptoms of OA and the genesis of pain by David J. Hunter, MBBS PhD,1,2 Jason J. McDougall, BSc PhD,3 and Francis J. Keefe4(PubMed)
(358) Biochemical markers identify influences on bone and cartilage degradation in osteoarthritis--the effect of sex, Kellgren-Lawrence (KL) score, body mass index (BMI), oral salmon calcitonin (sCT) treatment and diurnal variation by Karsdal MA1, Byrjalsen I, Bay-Jensen AC, Henriksen K, Riis BJ, Christiansen C.(PubMed)
(359) Oral salmon calcitonin reduces Lequesne's algofunctional index scores and decreases urinary and serum levels of biomarkers of joint metabolism in knee osteoarthritis by Manicourt DH1, Azria M, Mindeholm L, Thonar EJ, Devogelaer JP.(PubMed)
(360) Calcitonin(The free dictionary)
(361) Dietary omega-3 fatty acids aid in the modulation of inflammation and metabolic healt by Angela M. Zivkovic, Natalie Telis, J. Bruce German, and Bruce D. Hammock(PubMed)

                        

The Smoothie of Alfalfa Sprouts, curcumin and Green Tea for Prevention and Treatment of Cervical Dysplasia


Kyle J. Norton(Scholar, Master of Nutrients), all right reserved.
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

The smoothie for prevention and treatment of Cervical Dysplasia 
Yield: 2 servings (about 8 ounces each)
1 1/2 cup sweet potato
1 tsp curcumin
1 cup green tea drink (Make from 4 grams of green tea, a slice of ginger and a cup of hot water lipped for 5 minutes, and let cool to room temperature)

1. Place all ingredients in a blender and puree about 1 minute
2. Blend on high speed about 1 minute or until the mixture is thick and the ice is well crushed.
3. Serve immediately

The finding of a natural source for treatment of Cervical Dysplasia ) has been running into many obstacles, many ingredients showed initially with promising result in animal studies have not produced same potentials in large sample size and mutli centers human trials.

Cervical Dysplasia is an early stage of cervical cancer as the result of irregular cell growth occurred on the surface lining of the cervix or endocervical canal, the opening between the uterus and the vagina. Epidemiological and preclinical evidence suggests that polyphenolic phytochemicals,  epigallocatechin gallate, curcumin from curry from tea possess cancer chemopreventive properties(3).

Green tea contains more amount of antioxidants than any drinks or food with the same volume, and is the leaves of Camellia sinensis, undergone minimal oxidation during processing, originated from China. Its polyphenon E, an green tea extract (containing 800 mg epigallocatechin gallate), may process anti Cervical Dysplasia in women with persistent human papillomavirus (HPV) infection and low-grade cervical intraepithelial neoplasia (CIN1)(1).

According to the The Catholic University of Korea, the green tea extracts (polyphenon E; poly E and (-)-epigallocatechin-3-gallate [EGCG]) in a form of ointment and capsule are effective for treating cervical lesions with 69% response rate(2).

Turmeric is a perennial plant in the genus Curcuma, belonging to the family Zingiberaceae, native to tropical South Asia. Its phytochemical curcumin may be effective for chemoprevention of cancer(4).
According to the Medical Research Center, Kasturba, India, Curcuma longa Linn extract, arrested low-grade squamous intraepithelialneoplasia (LSIL) a 12 week intervention through attenuated the circulating IL-6 pro inflammatory levels(5).
Dr. Prusty BK and Dr. Das BC. in thestudy of the effectiveness of curcumin against human papillomavirus (HPV) transcription and AP-1 activity in HeLa cells suggested that curcumin may be a novel therapeutic ingredient to control pathogenic HPV infection through its potent antioxidation(6).

Phytoestrogen, such as isoflavonoids found in legume with both estrogenic and antiestrogentic effect  depending to the levels of estrogen in women  may inhibit the induction of  Cervical
Dysplasia(7). Accordi,ng to the University of Hawaii, five isoflavonoids (genistein, glycitein, daidzein, O-desmethylangolensin, and equol), two flavonoids (hesperetin and naringenin), and two lignans (enterodiol and enterolactone) exhibited a positive association between specific
phytoestrogens and premalignancies of the cervix(8))(3).
Dr. Fedotcheva TA and colleagues said, "the half aximal inhibitory concentration (IC50) value of genistein (0.2 mM) for the growth inhibition of HeLa cells is at least ten times higher than that one of tamoxifen and cisplatin--drugs, used in cervical cancer treatment"(9).

The effectiveness of Alfalfa Sprouts, curcumin and Green Tea may serve as cornerstones of pharmaceutical target for further studies in production of a potential medication for for Reduced Risk  and treatment of Cervical Dysplasia with little or no adverse effects.

Women who are at increased risk of Cervical Dysplasia  due to sexual active with many partners,..... should drink the smoothie twice a day and women with Cervical Dysplasia should drink as much as they can, depending to the digestive toleration.
Life style and dietary patter change are recommended.

All Forms of Arthritis are Curable
You Can Eliminate Osteoarthritis
By addressing the Underlying Causes through Clinical Trials and Studies

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Super foods Library, Eat Yourself Healthy With The Best of the Best Nature Has to Offer

References
(1) Results of a phase II randomized, double-blind, placebo-controlled trial of Polyphenon E in women with persistent high-risk HPV infection and low-grade cervical intraepithelial neoplasia by Garcia FA1, Cornelison T2, Nuño T3, Greenspan DL4, Byron JW5, Hsu CH6, Alberts DS6, Chow HH6(PubMed)
(2) Protective effects of green tea extracts (polyphenon E and EGCG) on human cervical lesions by Ahn WS1, Yoo J, Huh SW, Kim CK, Lee JM, Namkoong SE, Bae SM, Lee IP.(PubMed)
(3) Dietary polyphenolic phytochemicals--promising cancer chemopreventive agents in humans? A review of their clinical properties by Thomasset SC1, Berry DP, Garcea G, Marczylo T, Steward WP, Gescher AJ.(PubMed)
(4) Phase I clinical trial of curcumin, a chemopreventive agent, in patients with high-risk or pre-malignant lesions by Cheng AL1, Hsu CH, Lin JK, Hsu MM, Ho YF, Shen TS, Ko JY, Lin JT, Lin BR, Ming-Shiang W, Yu HS, Jee SH, Chen GS, Chen TM, Chen CA, Lai MK, Pu YS,Pan MH, Wang YJ, Tsai CC, Hsieh CY.(PubMed)
(5) Chemopreventive potential and safety profile of a Curcuma longa extract in women withcervical low-grade squamous intraepithelial neoplasia by Joshi JV1, Paradkar PH, Jagtap SS, Agashe SV, Soman G, Vaidya AB.(PubMed)
(6) Constitutive activation of transcription factor AP-1 in cervical cancer and suppression of human papillomavirus (HPV) transcription and AP-1 activity in HeLa cells by curcumin by Prusty BK1, Das BC.(PubMed)
(7) Phytoestrogen content and estrogenic effect of legume fodder by Saloniemi H1, Wähälä K, Nykänen-Kurki P, Kallela K, Saastamoinen I.(PubMed)
(8) Reports: plasma and dietary phytoestrogens and risk of premalignant lesions of the cervix by Hernandez BY1, McDuffie K, Franke AA, Killeen J, Goodman MT.(PubMed)
(9) [Cytoprotective Effects of Phytoestrogen Genistein against Cancer Cells].[Article in Russian] by Fedotcheva TA, Shirokih KE, Matyushin AI, Rzheznikov VM, Kovtun VY, Shimanovskii NL.(PubMed)