Kyle J. Norton (Scholar)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.
Musculoskeletal disorders (MSDs) are medical condition mostly caused by work related occupations and working environment, affecting patients’ muscles, joints, tendons, ligaments and nerves and developing over time. A community sample of 73 females and 32 males aged 85 and over underwent a standardised examination at home. Musculoskeletal pain was reported by 57% of those interviewed. A major restriction of joint movement range was frequent in the shoulder but uncommon in other joints(1).
Types of Musculo-Skeletal disorders in elder(2)
1. Osteoarthritis
2. Gout
3. Rheumatoid Arthritis
4. Polymalagia Arthritis
5. Cervical myleopathy and spinal canal stenosis
6. Osteoporosis
7. Low back pain
8. Fibromyalgia
Osteoarthritis
Osteoarthritis (OA), a form of arthritis, is defined as a condition of as a result of aging causes of wear and tear on a joint, affecting over 25 million people in the United States in alone. University of Porto Medical School indicated that one must understand the differences in prevalence and incidence estimates of osteoarthritis (OA), according to case definition, in knee, hip and hand joints(3).
The characteristics of osteoarthritis are aching pain(5), stiffness(6), or difficulty of moving the joint or joints(7). The pain usually gets worse in change of weather, at night and in the advanced diseases, the pain can occur even at rest(8). Today management of osteoarthritis (OA) focuses on pain relief and improved physical function through pharmacological, non pharmacological, and surgical treatments(4).
The Treatment
B. In herbal and traditional Chinese medicine perspective
B.5.. Topical Remedies
1. Topical Ginger
Ginger, one of the herbal medicine used as cooking spice and best known for its treatment in warming the stomach, use as topical remedy, it has been found to consist the potential for treatment of osteoarthritis, according to Dr. Therkleson T., in the study of 20 adults with moderate to severe osteoarthritis(414). On a self-report arthritis Health Assessment Questionnaire, topical ginger showed to relief osteoarthritic symptoms, in both body physiological recordings and pain scale(415).
The Edith Cowan University, in the study of a self-treatment using the ginger patch for a further 24 week, showed that ginger treatment relieve symptoms, improve the overall health, and increase independence of people with chronic osteoarthritis(416).
2. Capsaicin cream
Topical Capsaicin cream used for treatment of soft tissue with a pharmaceutical name of Finalgon®(420), may be effective for treatment of osteoarthritis in dependent to its concentration.
In a randomized, single-blind, 28-day study conducted by Research Testing Laboratories, capsaicin cream (0.25%) applied twice daily, showed to relieve severity of osteoartghritic pain with side effect of burning sensation(419).
Civamide cream produced by Winston Pharmaceuticals, approved by FDA, civamide cream is a cis-isomer of capsaicin topical medication used for treatment of osteoarthritis of the knee and other neuropathic pain(417). In the study by Northwestern University Feinberg School of Medicine, in patients with OA of the knee, civamide cream 0.075% or a lower dose of civamide cream, 0.01% effectively in relieve pain and improve physical functions(418).
Arthritis Is Curable
You Can Eliminate Osteoarthritis
By addressing the Underlying Causes through Clinical Trials and Studies
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Super foods Library, Eat Yourself Healthy With The Best of the Best Nature Has to Offer recommended by Kyle J. Norton
Back to Kyle J. Norton Home page http://kylejnorton.blogspot.ca
References
(1) Prevalence of rheumatic symptoms, rheumatoid arthritis, ankylosing spondylitis, and gout in Shanghai, China: a COPCORD study by Dai SM1, Han XH, Zhao DB, Shi YQ, Liu Y, Meng JM.(PubMed)
(2) Musculoskeletal Disorders in the Elderly by Ramon Gheno, Juan M. Cepparo, Cristina E. Rosca,1 and Anne Cotten(PMC)
(3) The effect of osteoarthritis definition on prevalence and incidence estimates: a systematic review by Pereira D1, Peleteiro B, Araújo J, Branco J, Santos RA, Ramos E.(PubMed)
(4) Effect of therapeutic aquatic exercise on symptoms and function associated with lower limb osteoarthritis: systematic review with meta-analysis by Waller B1, Ogonowska-Slodownik A2, Vitor M3, Lambeck J4, Daly D5, Kujala UM6, Heinonen A7.(PubMed)
(5) Effects of therapeutic ultrasound on pain, physical functions and safety outcomes in patients with kneeosteoarthritis: A systematic review and meta-analysis by Zhang C1, Xie Y2, Luo X3, Ji Q3, Lu C3, He C4, Wang P3.(PubMed)
(6) Oral intake of purple passion fruit peel extract reduces pain and stiffness and improves physical function in adult patients with knee osteoarthritis by Farid R1, Rezaieyazdi Z, Mirfeizi Z, Hatef MR, Mirheidari M, Mansouri H, Esmaelli H, Bentley G, Lu Y, Foo Y, Watson RR.(PubMed)
(7) Functional ability, mobility, and pain before and after knee replacement in patients aged 75 and older: a cross-sectional study by Limnell K1, Jämsen E, Huhtala H, Jäntti P, Puolakka T, Jylhä M.(PubMed)
(8) The symptoms of OA and the genesis of pain by David J. Hunter, MBBS PhD,1,2 Jason J. McDougall, BSc PhD,3 and Francis J. Keefe4(PubMed)
(316) The use of calcium and vitamin D in the management of osteoporosis by John A Sunyecz(PubMed)
(414) Topical Ginger Treatment With a Compress or Patch for Osteoarthritis Symptoms. by Therkleson T1.(PubMed)
(415) Ginger Therapy for Osteoarthritis: A Typical Case by Therkleson T1.(PubMed)
(416) Topical Ginger Treatment With a Compress or Patch for Osteoarthritis Symptoms by Therkleson T1(PubMed)
(417) Zucapsaicin(Wikipedia)
(418) Civamide cream 0.075% in patients with osteoarthritis of the knee: a 12-week randomized controlled clinical trial with a longterm extension by Schnitzer TJ1, Pelletier JP, Haselwood DM, Ellison WT, Ervin JE, Gordon RD, Lisse JR, Archambault WT, Sampson AR, Fezatte HB, Phillips SB, Bernstein JE.(PubMed)
Saturday, April 16, 2016
The Smoothie of Unripe Whole Foods Papaya and Fortified Low Fat Milk For Diabetic Pregnancy
Kyle J. Norton(Scholar, Master of Nutrients), all right reserved.
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.
The smoothie for reduced risk and treatment of Diabetic' Pregnancy
Yield:2 servings (about 8 ounces each)
1 1/2 cup whole food Papaya
1 cup fortified vitamin D low fat milk
1. Place all ingredients in a blender and puree about 1 minute
2. Blend on high speed about 1 minute or until the mixture is thick and the ice is well crushed.
3. Serve immediately
The finding of a natural source for reduced risk and treatment of Diabetes and Pregnancy has encountered many obstacles, many ingredients showed initially the promising result in animal studies have not produced same potentials in either large sample size and mutli centers human trials.
Scientists in some well known institutions may have found the therapeutic and potential ingredients from natural sources(Green tea and grape) for reduced risk and treatment of Diabetes and Pregnancy.
Diabetes are conditions caused by insufficient insulin entering the bloodstream to regulate the glucose. It is either caused by cells in pancreas dying off or receptor sites clogged up by fat and cholesterol. In some cases, diabetes are also caused by allergic reactions of cells in the immune system.
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.
The smoothie for reduced risk and treatment of Diabetic' Pregnancy
Yield:2 servings (about 8 ounces each)
1 1/2 cup whole food Papaya
1 cup fortified vitamin D low fat milk
1. Place all ingredients in a blender and puree about 1 minute
2. Blend on high speed about 1 minute or until the mixture is thick and the ice is well crushed.
3. Serve immediately
The finding of a natural source for reduced risk and treatment of Diabetes and Pregnancy has encountered many obstacles, many ingredients showed initially the promising result in animal studies have not produced same potentials in either large sample size and mutli centers human trials.
Scientists in some well known institutions may have found the therapeutic and potential ingredients from natural sources(Green tea and grape) for reduced risk and treatment of Diabetes and Pregnancy.
Diabetes are conditions caused by insufficient insulin entering the bloodstream to regulate the glucose. It is either caused by cells in pancreas dying off or receptor sites clogged up by fat and cholesterol. In some cases, diabetes are also caused by allergic reactions of cells in the immune system.
Women with with pre-existing type 1 or type 2 diabetes should pay attention to preconception care recommended by the Society of Obstetricians and Gynaecologists of Canada (SOGC).
According to the joint study led by the Wollongong Hospital, Wollongong, the prevalence of hyperglycaemia in pregnancy (HIP) was 13.1% with diabetes mellitus in pregnancy (DIP) being 0.4% and gestational diabetes mellitus (GDM) being 12.7% in Australia(1).
Wopmen with Type II Diabetes during pregancy may also be thinking to add whole food papaya into their diet. the recent study suggested(7)
The finding not only showed the effectiveness of unripe pawpaw fruit (Carica papaya) in inhibition α-amylase, α-glucosidase, but also induced lipid peroxidation in a dose-dependent manner, in rat pancreas(2).
The key enzymes of α-amylase, α-glucosidase, involved in the digestion of carbohydrates, have been linked to onset of type 2 diabetes. Inhibition of these enzymes can significantly reduce the post-prandial increase of blood glucose and have been considered by therapists in use for management of blood glucose level in type 2 diabetic and borderline patients(3).
In streptozotocin-induced diabetic rats study, the aqueous extract of leaves of C. papaya administered strongly controlled blood glucose levels(9), through prevention of hepatocyte disruption, as well as accumulation of glycogen and lipids via its hypoglycemic and antioxidant effect(4)
In a new study, conducted by the researchers at the Davis Heart and Lung Research Institute, fermented papaya preparation was tested whether it improves dermal wound healing outcomes in adult diabetic mice by preventing the risk of infections(5).
The result was astonishing, the fermentation not only up regulated the Sp1 DNA binding activity(modulating the cellular response to DNA damage) in Peripheral blood mononuclear cells (PBMC) but also the protein and mRNA expression of Rac2(regulates a number of cellular functions)(6).
A randomized controlled clinical trial conducted at the Cardiac Centre, ANDI Centre of Excellence for Biomedical and Biomaterials Research and Department of Biosciences University of Mauritius, suggested that oral administration of 6g FPP®/day for a period of 14 weeks could improve the general health status of several organs targeted by oxidative stress duringdiabetes and suggested that the supplement may be used in the management the complications of diabetes such as cardiovascular disease, neurological disease and other conditions worsened by overt inflammation and oxidative stress(7).
Women who are diabetes with pregnancy should drink 4 servings daily depending to digestive toleration.
Change life style and diet pattern are also recommended.
All Forms of Arthritis are Curable
You Can Eliminate Osteoarthritis
By addressing the Underlying Causes through Clinical Trials and Studies
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to General health http://kylejnorton.blogspot.ca/p/general-health.html
Back to Kyle J. Norton Home page http://kylejnorton.blogspot.ca
References
(1) The prevalence of hyperglycaemia in pregnancy in Australia by Moses RG1, Wong VC1, Lambert K1, Morris GJ2, San Gil F1.(PubMed)
(2) Inhibition of key enzymes linked to type 2 diabetes and sodium nitroprusside-induced lipid peroxidation in rat pancreas by water-extractable phytochemicals from unripe pawpaw fruit (Carica papaya) by Oboh G, Olabiyi AA, Akinyemi AJ, Ademiluyi AO.(PubMed)
(3) Natural products as alpha-amylase and alpha-glucosidase inhibitors and their hypoglycaemic potential in the treatment of diabetes: an update by Tundis R1, Loizzo MR, Menichini F.(PubMed)
(4) Antihyperglycemic and hypolipidemic activities of aqueous extract ofCarica papaya Linn. leaves in alloxan-induced diabetic rats by Maniyar Y, Bhixavatimath P.(PubMed)
(5) Hypoglycemic effect of Carica papaya leaves in streptozotocin-induced diabetic rats by Juárez-Rojop IE1, Díaz-Zagoya JC, Ble-Castillo JL, Miranda-Osorio PH, Castell-Rodríguez AE, Tovilla-Zárate CA, Rodríguez-Hernández A, Aguilar-Mariscal H, Ramón-Frías T, Bermúdez-Ocaña DY.(PubMed)
(6) Correction of aberrant NADPH oxidase activity in blood-derived mononuclear cells from type II diabetes mellitus patients by a naturally fermented papaya preparation by Dickerson R1, Deshpande B, Gnyawali U, Lynch D, Gordillo GM, Schuster D, Osei K, Roy S.(PubMed)
(7) Effects of a short term supplementation of a fermented papaya preparation on biomarkers of diabetes mellitus in a randomized Mauritian population by Somanah J1, Aruoma OI, Gunness TK, Kowelssur S, Dambala V, Murad F, Googoolye K, Daus D, Indelicato J, Bourdon E, Bahorun T.(PubMed)
According to the joint study led by the Wollongong Hospital, Wollongong, the prevalence of hyperglycaemia in pregnancy (HIP) was 13.1% with diabetes mellitus in pregnancy (DIP) being 0.4% and gestational diabetes mellitus (GDM) being 12.7% in Australia(1).
Wopmen with Type II Diabetes during pregancy may also be thinking to add whole food papaya into their diet. the recent study suggested(7)
The finding not only showed the effectiveness of unripe pawpaw fruit (Carica papaya) in inhibition α-amylase, α-glucosidase, but also induced lipid peroxidation in a dose-dependent manner, in rat pancreas(2).
The key enzymes of α-amylase, α-glucosidase, involved in the digestion of carbohydrates, have been linked to onset of type 2 diabetes. Inhibition of these enzymes can significantly reduce the post-prandial increase of blood glucose and have been considered by therapists in use for management of blood glucose level in type 2 diabetic and borderline patients(3).
In streptozotocin-induced diabetic rats study, the aqueous extract of leaves of C. papaya administered strongly controlled blood glucose levels(9), through prevention of hepatocyte disruption, as well as accumulation of glycogen and lipids via its hypoglycemic and antioxidant effect(4)
In a new study, conducted by the researchers at the Davis Heart and Lung Research Institute, fermented papaya preparation was tested whether it improves dermal wound healing outcomes in adult diabetic mice by preventing the risk of infections(5).
The result was astonishing, the fermentation not only up regulated the Sp1 DNA binding activity(modulating the cellular response to DNA damage) in Peripheral blood mononuclear cells (PBMC) but also the protein and mRNA expression of Rac2(regulates a number of cellular functions)(6).
A randomized controlled clinical trial conducted at the Cardiac Centre, ANDI Centre of Excellence for Biomedical and Biomaterials Research and Department of Biosciences University of Mauritius, suggested that oral administration of 6g FPP®/day for a period of 14 weeks could improve the general health status of several organs targeted by oxidative stress duringdiabetes and suggested that the supplement may be used in the management the complications of diabetes such as cardiovascular disease, neurological disease and other conditions worsened by overt inflammation and oxidative stress(7).
Women who are diabetes with pregnancy should drink 4 servings daily depending to digestive toleration.
Change life style and diet pattern are also recommended.
All Forms of Arthritis are Curable
You Can Eliminate Osteoarthritis
By addressing the Underlying Causes through Clinical Trials and Studies
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to General health http://kylejnorton.blogspot.ca/p/general-health.html
Back to Kyle J. Norton Home page http://kylejnorton.blogspot.ca
References
(1) The prevalence of hyperglycaemia in pregnancy in Australia by Moses RG1, Wong VC1, Lambert K1, Morris GJ2, San Gil F1.(PubMed)
(2) Inhibition of key enzymes linked to type 2 diabetes and sodium nitroprusside-induced lipid peroxidation in rat pancreas by water-extractable phytochemicals from unripe pawpaw fruit (Carica papaya) by Oboh G, Olabiyi AA, Akinyemi AJ, Ademiluyi AO.(PubMed)
(3) Natural products as alpha-amylase and alpha-glucosidase inhibitors and their hypoglycaemic potential in the treatment of diabetes: an update by Tundis R1, Loizzo MR, Menichini F.(PubMed)
(4) Antihyperglycemic and hypolipidemic activities of aqueous extract ofCarica papaya Linn. leaves in alloxan-induced diabetic rats by Maniyar Y, Bhixavatimath P.(PubMed)
(5) Hypoglycemic effect of Carica papaya leaves in streptozotocin-induced diabetic rats by Juárez-Rojop IE1, Díaz-Zagoya JC, Ble-Castillo JL, Miranda-Osorio PH, Castell-Rodríguez AE, Tovilla-Zárate CA, Rodríguez-Hernández A, Aguilar-Mariscal H, Ramón-Frías T, Bermúdez-Ocaña DY.(PubMed)
(6) Correction of aberrant NADPH oxidase activity in blood-derived mononuclear cells from type II diabetes mellitus patients by a naturally fermented papaya preparation by Dickerson R1, Deshpande B, Gnyawali U, Lynch D, Gordillo GM, Schuster D, Osei K, Roy S.(PubMed)
(7) Effects of a short term supplementation of a fermented papaya preparation on biomarkers of diabetes mellitus in a randomized Mauritian population by Somanah J1, Aruoma OI, Gunness TK, Kowelssur S, Dambala V, Murad F, Googoolye K, Daus D, Indelicato J, Bourdon E, Bahorun T.(PubMed)
Most Common Diseases of 50plus: Pulmonary vascular disease(Respiratory disease): Pulmonary edema- Treatment In traditional Chinese medicine perspective
Kyle J. Norton(Scholar and Master of Nutrients, all right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.
Respiratory Disease
Respiratory Disease is defined as medical conditions, affecting the breathing organ and tissues including Inflammatory lung disease, Obstructive lung diseases, Restrictive lung diseases, Respiratory tract infections, trachea, bronchi, bronchioles, alveoli, the nerves and muscles breathing, etc,.
Pulmonary vascular disease: Pulmonary edema
Pulmonary vascular disease is defined as a condition of blood flow to the lung’s artery is blocked suddenly due to a blood clot somewhere in the body, including pulmonary embolism, chronic thromboembolic disease, pulmonary arterial hypertension, pulmonary veno-occlusive disease, pulmonary arteriovenous malformations, pulmonary edema, etc.
The Treatment
C. In traditional Chinese medicine
1. Ligusticum chuanxiong Hort., Dalbergia odorifera T. Chen and Corydalis yanhusuo WT Wang
In the study of incorporating the chemical predictors, target predictors and network construction approaches, an integrated system of TCM has been constructed to systematically uncover the underlying action mechanisms of TCM. From three representative Chinese herbs, i.e., Ligusticum chuanxiong Hort., Dalbergia odorifera T. Chen and Corydalis yanhusuo WT Wang which have been widely used in CVD treatment, by combinational use of drug absorption, distribution, metabolism and excretion (ADME) screening and network pharmacology techniques, showed that the result provides new information on the efficiency of the Chinese herbs for the treatment of CVD and also explains one of the basic theories of TCM, i.e., “multiple herbal drugs can treat one disease”. The predicted potential targets were then mapped to target-disease and target-signal pathway connections, which revealed the relationships of the active ingredients with their potential targets, diseases and signal systems. This means that for the first time, the action mechanism of these three important Chinese herbs for the treatment of CVD is uncovered, by generating and identifying both their active ingredients and novel targets specifically related to CVD, which clarifies some of the common conceptions in TCM, and thus provides clues to modernize such specific herbal medicines(72).
2. Wind dispelling and dampness removing herbs
In the study to observe the clinical efficiency and safety of Benazepril and wind dispelling and dampness removing Chinese herbs were singly or combined used in patients with stage 3 chronic kidney disease (CKD 3), and to provide effective integrative medicine methods for treatment of CKD 3, showed that
for CGN CKD 3 patients, treatment by Benazepril combined with wind dispelling and dampness removing Chinese herbs showed favorable renal protective effects. It delayed the progress of renal failure, significantly improve the overall clinical efficacy. It was an effective treatment method for CGN CKD 3 patients with good patient tolerance and less adverse reactions(73).
3. Cao Gou
Cao Gou also Known as Cardamom. The acrid, warm, aromic herb has been used in TCM to stomach pain, flatulence, belching, indigestion, vomiting, malarial disorders, etc. as it dries Dampness, warms the Middle Burner, etc., by enhancing the functions of spleen and stomach channels.
a. Blood pressure, fibrinolysis and antioxidant
In the investigation of Elettaria cardamomum (L.) Maton. (Small cardamom) fruit powder and its effects in cardiovascular desieases found that the fruit powder antioxidant significantly (p<0.05) increased by 90% at the end of 3 months and effectively reduces blood pressure, enhances fibrinolysis, according to the study of "Blood pressure lowering, fibrinolysis enhancing and antioxidant activities of cardamom (Elettaria cardamomum)" by Verma SK, Jain V, Katewa SS.(74).
b. Platelet aggregation and lipid peroxidation
In the study of cardamom extract and it effects in platelet aggregation and lipid peroxidation found that an increase in concentration of cardamom has decreased the MDA formation significantly. Hence, it may be said that aqueous extract of cardamom may have component(s), which protect platelets from aggregation and lipid peroxidation, according to the study of "Cardamom extract as inhibitor of human platelet aggregation" by Suneetha WJ, Krishnakantha TP.(75).
c. Diuretic
In the observation of and it diuretic and sedative activities effects found that cardamom exhibits gut excitatory and inhibitory effects mediated through cholinergic and Ca++ antagonist mechanisms respectively and lowers BP via combination of both pathways. The diuretic and sedative effects may offer added value in its use in hypertension and epilepsy, according to the study of "Gut modulatory, blood pressure lowering, diuretic and sedative activities of cardamom" by Gilani AH, Jabeen Q, Khan AU, Shah AJ.(76).
All Forms of Arthritis are Curable
You Can Eliminate Osteoarthritis
By addressing the Underlying Causes through Clinical Trials and Studies
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to General health http://kylejnorton.blogspot.ca/p/general-health.html
Back to Kyle J. Norton Home page http://kylejnorton.blogspot.ca
Sources
(a) http://www.ncbi.nlm.nih.gov/pubmed/19739476
(72) http://www.ncbi.nlm.nih.gov/pubmed/23202964
(73) http://www.ncbi.nlm.nih.gov/pubmed/22686073
(74) http://www.ncbi.nlm.nih.gov/pubmed/20361714
(75) http://www.ncbi.nlm.nih.gov/pubmed/16106388
(76) http://www.ncbi.nlm.nih.gov/pubmed/18037596
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.
Respiratory Disease
Respiratory Disease is defined as medical conditions, affecting the breathing organ and tissues including Inflammatory lung disease, Obstructive lung diseases, Restrictive lung diseases, Respiratory tract infections, trachea, bronchi, bronchioles, alveoli, the nerves and muscles breathing, etc,.
Pulmonary vascular disease: Pulmonary edema
Pulmonary vascular disease is defined as a condition of blood flow to the lung’s artery is blocked suddenly due to a blood clot somewhere in the body, including pulmonary embolism, chronic thromboembolic disease, pulmonary arterial hypertension, pulmonary veno-occlusive disease, pulmonary arteriovenous malformations, pulmonary edema, etc.
Pulmonary edema is defined as a condition of fluid accumulation in the air spaces and parenchyma of the lungs of that can lead to difficult of breathing and respiratory failure.
1. Ligusticum chuanxiong Hort., Dalbergia odorifera T. Chen and Corydalis yanhusuo WT Wang
In the study of incorporating the chemical predictors, target predictors and network construction approaches, an integrated system of TCM has been constructed to systematically uncover the underlying action mechanisms of TCM. From three representative Chinese herbs, i.e., Ligusticum chuanxiong Hort., Dalbergia odorifera T. Chen and Corydalis yanhusuo WT Wang which have been widely used in CVD treatment, by combinational use of drug absorption, distribution, metabolism and excretion (ADME) screening and network pharmacology techniques, showed that the result provides new information on the efficiency of the Chinese herbs for the treatment of CVD and also explains one of the basic theories of TCM, i.e., “multiple herbal drugs can treat one disease”. The predicted potential targets were then mapped to target-disease and target-signal pathway connections, which revealed the relationships of the active ingredients with their potential targets, diseases and signal systems. This means that for the first time, the action mechanism of these three important Chinese herbs for the treatment of CVD is uncovered, by generating and identifying both their active ingredients and novel targets specifically related to CVD, which clarifies some of the common conceptions in TCM, and thus provides clues to modernize such specific herbal medicines(72).
2. Wind dispelling and dampness removing herbs
In the study to observe the clinical efficiency and safety of Benazepril and wind dispelling and dampness removing Chinese herbs were singly or combined used in patients with stage 3 chronic kidney disease (CKD 3), and to provide effective integrative medicine methods for treatment of CKD 3, showed that
for CGN CKD 3 patients, treatment by Benazepril combined with wind dispelling and dampness removing Chinese herbs showed favorable renal protective effects. It delayed the progress of renal failure, significantly improve the overall clinical efficacy. It was an effective treatment method for CGN CKD 3 patients with good patient tolerance and less adverse reactions(73).
3. Cao Gou
Cao Gou also Known as Cardamom. The acrid, warm, aromic herb has been used in TCM to stomach pain, flatulence, belching, indigestion, vomiting, malarial disorders, etc. as it dries Dampness, warms the Middle Burner, etc., by enhancing the functions of spleen and stomach channels.
a. Blood pressure, fibrinolysis and antioxidant
In the investigation of Elettaria cardamomum (L.) Maton. (Small cardamom) fruit powder and its effects in cardiovascular desieases found that the fruit powder antioxidant significantly (p<0.05) increased by 90% at the end of 3 months and effectively reduces blood pressure, enhances fibrinolysis, according to the study of "Blood pressure lowering, fibrinolysis enhancing and antioxidant activities of cardamom (Elettaria cardamomum)" by Verma SK, Jain V, Katewa SS.(74).
b. Platelet aggregation and lipid peroxidation
In the study of cardamom extract and it effects in platelet aggregation and lipid peroxidation found that an increase in concentration of cardamom has decreased the MDA formation significantly. Hence, it may be said that aqueous extract of cardamom may have component(s), which protect platelets from aggregation and lipid peroxidation, according to the study of "Cardamom extract as inhibitor of human platelet aggregation" by Suneetha WJ, Krishnakantha TP.(75).
c. Diuretic
In the observation of and it diuretic and sedative activities effects found that cardamom exhibits gut excitatory and inhibitory effects mediated through cholinergic and Ca++ antagonist mechanisms respectively and lowers BP via combination of both pathways. The diuretic and sedative effects may offer added value in its use in hypertension and epilepsy, according to the study of "Gut modulatory, blood pressure lowering, diuretic and sedative activities of cardamom" by Gilani AH, Jabeen Q, Khan AU, Shah AJ.(76).
All Forms of Arthritis are Curable
You Can Eliminate Osteoarthritis
By addressing the Underlying Causes through Clinical Trials and Studies
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to General health http://kylejnorton.blogspot.ca/p/general-health.html
Back to Kyle J. Norton Home page http://kylejnorton.blogspot.ca
Sources
(a) http://www.ncbi.nlm.nih.gov/pubmed/19739476
(72) http://www.ncbi.nlm.nih.gov/pubmed/23202964
(73) http://www.ncbi.nlm.nih.gov/pubmed/22686073
(74) http://www.ncbi.nlm.nih.gov/pubmed/20361714
(75) http://www.ncbi.nlm.nih.gov/pubmed/16106388
(76) http://www.ncbi.nlm.nih.gov/pubmed/18037596
Friday, April 15, 2016
Most Common Disease of50plus: The Clinical trials and Studies of Musculo-Skeletal disorders(MSDs) - Osteoarthritis: Treatment In herbal and traditional Chinese medicine - The Fabulous Supplements for osteoarthritis
Kyle J. Norton (Scholar)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.
Musculoskeletal disorders (MSDs) are medical condition mostly caused by work related occupations and working environment, affecting patients’ muscles, joints, tendons, ligaments and nerves and developing over time. A community sample of 73 females and 32 males aged 85 and over underwent a standardised examination at home. Musculoskeletal pain was reported by 57% of those interviewed. A major restriction of joint movement range was frequent in the shoulder but uncommon in other joints(1).
Types of Musculo-Skeletal disorders in elder(2)
1. Osteoarthritis
2. Gout
3. Rheumatoid Arthritis
4. Polymalagia Arthritis
5. Cervical myleopathy and spinal canal stenosis
6. Osteoporosis
7. Low back pain
8. Fibromyalgia
Osteoarthritis
Osteoarthritis (OA), a form of arthritis, is defined as a condition of as a result of aging causes of wear and tear on a joint, affecting over 25 million people in the United States in alone. University of Porto Medical School indicated that one must understand the differences in prevalence and incidence estimates of osteoarthritis (OA), according to case definition, in knee, hip and hand joints(3).
The characteristics of osteoarthritis are aching pain(5), stiffness(6), or difficulty of moving the joint or joints(7). The pain usually gets worse in change of weather, at night and in the advanced diseases, the pain can occur even at rest(8). Today management of osteoarthritis (OA) focuses on pain relief and improved physical function through pharmacological, non pharmacological, and surgical treatments(4).
The Treatment
B. In herbal and traditional Chinese medicine perspective
B. 4. The Fabulous Supplements for osteoarthritis
1. Glucosamine
Glucosamine, a compound of the simple sugar glucose and the amino acid glutamine, is a precursor for glycosaminoglycans(194), a major component of joint cartilage(195). Treatment of glucosamine sulfate, chondroitin sulfate, hyaluronic acid, collagen hydrolysate, or nutrients, such as antioxidants and omega-3 fatty acids showed to prevent cartilage degeneration and treat arthritis, according to study(195).
2. Chondroitin
Sulfated glycosaminoglycan (GAG), found in cartilage around joints in the body id a chemical composed of alternating sugars (N-acetylgalactosamine and glucuronic acid).
The chemical compound has been used as nonsteroidal anti-inflammatory drugs for treatment of osteoarthritis by it self or combination with viscosupplementation, according to study(367).
The comparison of piascledine 300 and chondroitin sulfate for treatment of knee osteoarthritis study, also insisted that 3 capsules chondroitin sulfate per day or one capsule of avocado soybean unsaponifiable (ASU) improved the WOMAC-index decreased in both groups for approx. 50% to the end of therapy(368).
According to the Birmingham VA Medical Center, chondroitin, reliefs pain for patient with knee osteoarthritis with little adverse effects when compared with control(369) and its combination with glucosamine showed a greater effect in reducing pain, stiffness, functional limitation and joint swelling/effusion after 6 months in patients with painful knee osteoarthritis(370)(371),
3. Avocado soybean unsaponifiables (ASU)
Avocado soybean unsaponifiables (ASU) is a natural vegetable extract composed of one-third avocado oil and two-thirds soybean oil, may be used effectively for treatment of knee osteoarthritis to replace the use of analgesics and nonsteroidal antiinflammatory drugs (NSAIDs), according to the a three-month, prospective, randomized, double-blind, placebo-controlled, parallel-group trial(372). In patients with symptomatic osteoarthritis (OA) of the knee or hip, The extract inhibited functional disability, especially for patient with hip OA(373).
According to the Erasmus University Hospital of Brussels, daily intake of 300mg or 600mg of ASU, reduced intake of NSAIDs and analgesics by more than 50% in 71% in patient aged 45 to 80 years with femoro-tibial knee osteoarthritis(374) and improved symptoms of patients with OA of the knee and hip, according to the Universities of Exeter and Plymouth, Devon(375) probably through modulating OA pathogenesis by inhibiting a number of molecules and pathways(376), such as preventing the osteoarthritic osteoblast-induced inhibition of matrix molecule production in induced cartilage repair (377),
Arthritis Is Curable
You Can Eliminate Osteoarthritis
By addressing the Underlying Causes through Clinical Trials and Studies
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Super foods Library, Eat Yourself Healthy With The Best of the Best Nature Has to Offer recommended by Kyle J. Norton
Back to Kyle J. Norton Home page http://kylejnorton.blogspot.ca
References
(1) Prevalence of rheumatic symptoms, rheumatoid arthritis, ankylosing spondylitis, and gout in Shanghai, China: a COPCORD study by Dai SM1, Han XH, Zhao DB, Shi YQ, Liu Y, Meng JM.(PubMed)
(2) Musculoskeletal Disorders in the Elderly by Ramon Gheno, Juan M. Cepparo, Cristina E. Rosca,1 and Anne Cotten(PMC)
(3) The effect of osteoarthritis definition on prevalence and incidence estimates: a systematic review by Pereira D1, Peleteiro B, Araújo J, Branco J, Santos RA, Ramos E.(PubMed)
(4) Effect of therapeutic aquatic exercise on symptoms and function associated with lower limb osteoarthritis: systematic review with meta-analysis by Waller B1, Ogonowska-Slodownik A2, Vitor M3, Lambeck J4, Daly D5, Kujala UM6, Heinonen A7.(PubMed)
(5) Effects of therapeutic ultrasound on pain, physical functions and safety outcomes in patients with kneeosteoarthritis: A systematic review and meta-analysis by Zhang C1, Xie Y2, Luo X3, Ji Q3, Lu C3, He C4, Wang P3.(PubMed)
(6) Oral intake of purple passion fruit peel extract reduces pain and stiffness and improves physical function in adult patients with knee osteoarthritis by Farid R1, Rezaieyazdi Z, Mirfeizi Z, Hatef MR, Mirheidari M, Mansouri H, Esmaelli H, Bentley G, Lu Y, Foo Y, Watson RR.(PubMed)
(7) Functional ability, mobility, and pain before and after knee replacement in patients aged 75 and older: a cross-sectional study by Limnell K1, Jämsen E, Huhtala H, Jäntti P, Puolakka T, Jylhä M.(PubMed)
(8) The symptoms of OA and the genesis of pain by David J. Hunter, MBBS PhD,1,2 Jason J. McDougall, BSc PhD,3 and Francis J. Keefe4(PubMed)
(194) Glucosamine inhibits the synthesis of glycosaminoglycan chains on vascular smooth muscle cell proteoglycans by depletion of ATP by Little PJ1, Drennon KD, Tannock LR.(PubMed)
(195) Effects of Glucosamine and Chondroitin Sulfate on Cartilage Metabolism in OA: Outlook on Other Nutrient Partners Especially Omega-3 Fatty Acid by Jörg Jerosch(PubMed)
(367) Osteoarthritis in Latin America: Study of Demographic and Clinical Characteristics in 3040 Patients by Reginato AM1, Riera H, Vera M, Torres AR, Espinosa R, Esquivel JA, Felipe OJ, Blas JR, Rillo O, Papasidero S, Souto R, Rossi C, Molina JF, Ballesteros F,Radrigan F, Guibert M, Chico A, Gil ML, Camacho W, Urioste L, Garcia AK, Iraheta I, Gutierrez CE, Duarte M, Castañeda O, Coimbra I, Muñoz Louis R, Reveille J, Quintero M; Pan-American League of Associations for Rheumatology (PANLAR) Osteoarthritis Study Group(PubMed)(368) Efficacy and safety of piascledine 300 versus chondroitin sulfate in a 6 months treatment plus 2 months observation in patients with osteoarthritis of the knee by Pavelka K1, Coste P, Géher P, Krejci G.(PubMed)
(369) Chondroitin for osteoarthritis by Singh JA1, Noorbaloochi S, MacDonald R, Maxwell LJ.(PubMed)
(370) Combined chondroitin sulfate and glucosamine for painful knee osteoarthritis: a multicentre, randomised, double-blind, non-inferiority trial versus celecoxib by Hochberg MC1, Martel-Pelletier J2, Monfort J3, Möller I4, Castillo JR5, Arden N6, Berenbaum F7, Blanco FJ8, Conaghan PG9, Doménech G10, Henrotin Y11,Pap T12, Richette P13, Sawitzke A14, du Souich P15, Pelletier JP2; on behalf of the MOVES Investigation Group(PubMed)
(371) Glucosamine, chondroitin sulfate, and the two in combination for painful knee osteoarthritis by Clegg DO1, Reda DJ, Harris CL, Klein MA, O'Dell JR, Hooper MM, Bradley JD, Bingham CO 3rd, Weisman MH, Jackson CG, Lane NE, Cush JJ, Moreland LW,Schumacher HR Jr, Oddis CV, Wolfe F, Molitor JA, Yocum DE, Schnitzer TJ, Furst DE, Sawitzke AD, Shi H, Brandt KD, Moskowitz RW, Williams HJ.(PubMed)
(372) Efficacy and safety of avocado/soybean unsaponifiables in the treatment of symptomatic osteoarthritis of the knee and hip. A prospective, multicenter, three-month, randomized, double-blind, placebo-controlled trial by Blotman F1, Maheu E, Wulwik A, Caspard H, Lopez A.(PubMed)
(373) Symptomatic efficacy of avocado/soybean unsaponifiables in the treatment of osteoarthritis of the knee and hip: a prospective, randomized, double-blind, placebo-controlled, multicenter clinical trial with a six-month treatment period and a two-month followup demonstrating a persistent effect. by Maheu E1, Mazières B, Valat JP, Loyau G, Le Loët X, Bourgeois P, Grouin JM, Rozenberg S.(PubMed)
(374) Symptoms modifying effect of avocado/soybean unsaponifiables (ASU) in knee osteoarthritis. A double blind, prospective, placebo-controlled study by Appelboom T1, Schuermans J, Verbruggen G, Henrotin Y, Reginster JY.(PubMed)
(375) Avocado-soybean unsaponifiables (ASU) for osteoarthritis - a systematic review by Ernst E1.(PubMed)
(376) Management of Osteoarthritis with Avocado/Soybean Unsaponifiables by Christiansen BA1, Bhatti S2, Goudarzi R3, Emami S4.(PubMed)
(377) Avocado/soybean unsaponifiables prevent the inhibitory effect of osteoarthritic subchondral osteoblasts on aggrecan and type II collagen synthesis by chondrocytes by Henrotin YE1, Deberg MA, Crielaard JM, Piccardi N, Msika P, Sanchez C.(PubMed)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.
Musculoskeletal disorders (MSDs) are medical condition mostly caused by work related occupations and working environment, affecting patients’ muscles, joints, tendons, ligaments and nerves and developing over time. A community sample of 73 females and 32 males aged 85 and over underwent a standardised examination at home. Musculoskeletal pain was reported by 57% of those interviewed. A major restriction of joint movement range was frequent in the shoulder but uncommon in other joints(1).
Types of Musculo-Skeletal disorders in elder(2)
1. Osteoarthritis
2. Gout
3. Rheumatoid Arthritis
4. Polymalagia Arthritis
5. Cervical myleopathy and spinal canal stenosis
6. Osteoporosis
7. Low back pain
8. Fibromyalgia
Osteoarthritis
Osteoarthritis (OA), a form of arthritis, is defined as a condition of as a result of aging causes of wear and tear on a joint, affecting over 25 million people in the United States in alone. University of Porto Medical School indicated that one must understand the differences in prevalence and incidence estimates of osteoarthritis (OA), according to case definition, in knee, hip and hand joints(3).
The characteristics of osteoarthritis are aching pain(5), stiffness(6), or difficulty of moving the joint or joints(7). The pain usually gets worse in change of weather, at night and in the advanced diseases, the pain can occur even at rest(8). Today management of osteoarthritis (OA) focuses on pain relief and improved physical function through pharmacological, non pharmacological, and surgical treatments(4).
The Treatment
B. In herbal and traditional Chinese medicine perspective
B. 4. The Fabulous Supplements for osteoarthritis
1. Glucosamine
Glucosamine, a compound of the simple sugar glucose and the amino acid glutamine, is a precursor for glycosaminoglycans(194), a major component of joint cartilage(195). Treatment of glucosamine sulfate, chondroitin sulfate, hyaluronic acid, collagen hydrolysate, or nutrients, such as antioxidants and omega-3 fatty acids showed to prevent cartilage degeneration and treat arthritis, according to study(195).
2. Chondroitin
Sulfated glycosaminoglycan (GAG), found in cartilage around joints in the body id a chemical composed of alternating sugars (N-acetylgalactosamine and glucuronic acid).
The chemical compound has been used as nonsteroidal anti-inflammatory drugs for treatment of osteoarthritis by it self or combination with viscosupplementation, according to study(367).
The comparison of piascledine 300 and chondroitin sulfate for treatment of knee osteoarthritis study, also insisted that 3 capsules chondroitin sulfate per day or one capsule of avocado soybean unsaponifiable (ASU) improved the WOMAC-index decreased in both groups for approx. 50% to the end of therapy(368).
According to the Birmingham VA Medical Center, chondroitin, reliefs pain for patient with knee osteoarthritis with little adverse effects when compared with control(369) and its combination with glucosamine showed a greater effect in reducing pain, stiffness, functional limitation and joint swelling/effusion after 6 months in patients with painful knee osteoarthritis(370)(371),
3. Avocado soybean unsaponifiables (ASU)
Avocado soybean unsaponifiables (ASU) is a natural vegetable extract composed of one-third avocado oil and two-thirds soybean oil, may be used effectively for treatment of knee osteoarthritis to replace the use of analgesics and nonsteroidal antiinflammatory drugs (NSAIDs), according to the a three-month, prospective, randomized, double-blind, placebo-controlled, parallel-group trial(372). In patients with symptomatic osteoarthritis (OA) of the knee or hip, The extract inhibited functional disability, especially for patient with hip OA(373).
According to the Erasmus University Hospital of Brussels, daily intake of 300mg or 600mg of ASU, reduced intake of NSAIDs and analgesics by more than 50% in 71% in patient aged 45 to 80 years with femoro-tibial knee osteoarthritis(374) and improved symptoms of patients with OA of the knee and hip, according to the Universities of Exeter and Plymouth, Devon(375) probably through modulating OA pathogenesis by inhibiting a number of molecules and pathways(376), such as preventing the osteoarthritic osteoblast-induced inhibition of matrix molecule production in induced cartilage repair (377),
Arthritis Is Curable
You Can Eliminate Osteoarthritis
By addressing the Underlying Causes through Clinical Trials and Studies
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Super foods Library, Eat Yourself Healthy With The Best of the Best Nature Has to Offer recommended by Kyle J. Norton
Back to Kyle J. Norton Home page http://kylejnorton.blogspot.ca
References
(1) Prevalence of rheumatic symptoms, rheumatoid arthritis, ankylosing spondylitis, and gout in Shanghai, China: a COPCORD study by Dai SM1, Han XH, Zhao DB, Shi YQ, Liu Y, Meng JM.(PubMed)
(2) Musculoskeletal Disorders in the Elderly by Ramon Gheno, Juan M. Cepparo, Cristina E. Rosca,1 and Anne Cotten(PMC)
(3) The effect of osteoarthritis definition on prevalence and incidence estimates: a systematic review by Pereira D1, Peleteiro B, Araújo J, Branco J, Santos RA, Ramos E.(PubMed)
(4) Effect of therapeutic aquatic exercise on symptoms and function associated with lower limb osteoarthritis: systematic review with meta-analysis by Waller B1, Ogonowska-Slodownik A2, Vitor M3, Lambeck J4, Daly D5, Kujala UM6, Heinonen A7.(PubMed)
(5) Effects of therapeutic ultrasound on pain, physical functions and safety outcomes in patients with kneeosteoarthritis: A systematic review and meta-analysis by Zhang C1, Xie Y2, Luo X3, Ji Q3, Lu C3, He C4, Wang P3.(PubMed)
(6) Oral intake of purple passion fruit peel extract reduces pain and stiffness and improves physical function in adult patients with knee osteoarthritis by Farid R1, Rezaieyazdi Z, Mirfeizi Z, Hatef MR, Mirheidari M, Mansouri H, Esmaelli H, Bentley G, Lu Y, Foo Y, Watson RR.(PubMed)
(7) Functional ability, mobility, and pain before and after knee replacement in patients aged 75 and older: a cross-sectional study by Limnell K1, Jämsen E, Huhtala H, Jäntti P, Puolakka T, Jylhä M.(PubMed)
(8) The symptoms of OA and the genesis of pain by David J. Hunter, MBBS PhD,1,2 Jason J. McDougall, BSc PhD,3 and Francis J. Keefe4(PubMed)
(194) Glucosamine inhibits the synthesis of glycosaminoglycan chains on vascular smooth muscle cell proteoglycans by depletion of ATP by Little PJ1, Drennon KD, Tannock LR.(PubMed)
(195) Effects of Glucosamine and Chondroitin Sulfate on Cartilage Metabolism in OA: Outlook on Other Nutrient Partners Especially Omega-3 Fatty Acid by Jörg Jerosch(PubMed)
(367) Osteoarthritis in Latin America: Study of Demographic and Clinical Characteristics in 3040 Patients by Reginato AM1, Riera H, Vera M, Torres AR, Espinosa R, Esquivel JA, Felipe OJ, Blas JR, Rillo O, Papasidero S, Souto R, Rossi C, Molina JF, Ballesteros F,Radrigan F, Guibert M, Chico A, Gil ML, Camacho W, Urioste L, Garcia AK, Iraheta I, Gutierrez CE, Duarte M, Castañeda O, Coimbra I, Muñoz Louis R, Reveille J, Quintero M; Pan-American League of Associations for Rheumatology (PANLAR) Osteoarthritis Study Group(PubMed)(368) Efficacy and safety of piascledine 300 versus chondroitin sulfate in a 6 months treatment plus 2 months observation in patients with osteoarthritis of the knee by Pavelka K1, Coste P, Géher P, Krejci G.(PubMed)
(369) Chondroitin for osteoarthritis by Singh JA1, Noorbaloochi S, MacDonald R, Maxwell LJ.(PubMed)
(370) Combined chondroitin sulfate and glucosamine for painful knee osteoarthritis: a multicentre, randomised, double-blind, non-inferiority trial versus celecoxib by Hochberg MC1, Martel-Pelletier J2, Monfort J3, Möller I4, Castillo JR5, Arden N6, Berenbaum F7, Blanco FJ8, Conaghan PG9, Doménech G10, Henrotin Y11,Pap T12, Richette P13, Sawitzke A14, du Souich P15, Pelletier JP2; on behalf of the MOVES Investigation Group(PubMed)
(371) Glucosamine, chondroitin sulfate, and the two in combination for painful knee osteoarthritis by Clegg DO1, Reda DJ, Harris CL, Klein MA, O'Dell JR, Hooper MM, Bradley JD, Bingham CO 3rd, Weisman MH, Jackson CG, Lane NE, Cush JJ, Moreland LW,Schumacher HR Jr, Oddis CV, Wolfe F, Molitor JA, Yocum DE, Schnitzer TJ, Furst DE, Sawitzke AD, Shi H, Brandt KD, Moskowitz RW, Williams HJ.(PubMed)
(372) Efficacy and safety of avocado/soybean unsaponifiables in the treatment of symptomatic osteoarthritis of the knee and hip. A prospective, multicenter, three-month, randomized, double-blind, placebo-controlled trial by Blotman F1, Maheu E, Wulwik A, Caspard H, Lopez A.(PubMed)
(373) Symptomatic efficacy of avocado/soybean unsaponifiables in the treatment of osteoarthritis of the knee and hip: a prospective, randomized, double-blind, placebo-controlled, multicenter clinical trial with a six-month treatment period and a two-month followup demonstrating a persistent effect. by Maheu E1, Mazières B, Valat JP, Loyau G, Le Loët X, Bourgeois P, Grouin JM, Rozenberg S.(PubMed)
(374) Symptoms modifying effect of avocado/soybean unsaponifiables (ASU) in knee osteoarthritis. A double blind, prospective, placebo-controlled study by Appelboom T1, Schuermans J, Verbruggen G, Henrotin Y, Reginster JY.(PubMed)
(375) Avocado-soybean unsaponifiables (ASU) for osteoarthritis - a systematic review by Ernst E1.(PubMed)
(376) Management of Osteoarthritis with Avocado/Soybean Unsaponifiables by Christiansen BA1, Bhatti S2, Goudarzi R3, Emami S4.(PubMed)
(377) Avocado/soybean unsaponifiables prevent the inhibitory effect of osteoarthritic subchondral osteoblasts on aggrecan and type II collagen synthesis by chondrocytes by Henrotin YE1, Deberg MA, Crielaard JM, Piccardi N, Msika P, Sanchez C.(PubMed)
The Smoothie of Brazil Nut, Tomato and Green Tea In reduced Risk and Treatment of Acquired immunodeficiency syndrome (AIDS) associated nephropathy
Kyle J. Norton(Scholar, master of Nutrients, all right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.
Renal disease is associated to common complication in patients with human immunodeficiency virus (HIV) disease as a result of direct kidney infection with HIV or from the adverse effects of antiviral medication.
The smoothie for Reduced risk and Treatment of Acquired immunodeficiency syndrome (AIDS) associated nephropathy
Yield: 2 serving (about 8 ounce each)
1 cup Tomato
1/2 cup Brazil nut
1 cup green tea drink (Make from 4 grams of green tea, a slice of ginger and a cup of hot water lipped for 5 minute. Set aside for cooling to room temperature)
1. Place all ingredients in a blender and puree about 1 minute
2. Blend on high speed about 1 minute or until the mixture is thick and the ice is well crushed. Add more green tea drink if needed
3. Serve immediately
The dream of finding the natural ingredient for prevention and treatment of Acquired immunodeficiency syndrome (AIDS), without adverse effects in replacement of conventional medication has not been abated. Some ingredients have to discard because of not achieving the same potent results in human trials.
Scientist community may have found the smoothie(combined ingredients of garlic, olive and coconut oils) with potential and therapeutic value for reduced risk and treatment of Acquired immunodeficiency syndrome (AIDS)without adverse effects.
Human immunodeficiency virus (HIV) is a lentivirus that causes acquired immunodeficiency syndrome (AIDS) of which can lead to the progression of weakened immune system casues of infectous diseases and cancers. According to the studies, patients with human immunodeficiency virus (HIV) are asscoiated to low levels of vitamin A and selenium(1).
Selenium, a chemical element with symbol Se and antioxidant found in Brazil nut, plays an important role in protection of cell against significant impairments of antioxidative defenses induced human immunodeficiency virus (HIV) (2).
Dr. Delmas-Beauvieux MC and colleagues at the Université Bordeaux II, suggested, selenium supplementation could be of great interest in protecting cells against oxidative stress and glutathione peroxidase (GPX), and glutathione (GSH) are important in expression of natural enzymatic defense system in detoxifying hydrogen peroxide(3).
Vitamin A, a bi-polar molecule formed by bonds between carbon and hydrogen, is a fat soluble vitamin converted from beta-carotene, a powerful antioxidant. Accoridng to the The University of Maryland School of Medicine, deficiency of vitamin A in human immunodeficiency virus (HIV) infection has been associated with more progressive HIV disease(4).
Green tea has been a precious drink in traditional Chinese culture and used exceptional in socialization for more than 4000 thousand years. Due to its commercial values and health effects, green tea now has been cultivated all over the world in suitable climate.
Dr. Hamza A and Dr. Zhan CG. said, "(-)-epigallocatechin gallate (EGCG) from green tea is an inhibitor blocking gp120-CD4 binding" by blocking the initial step of HIV-1 entry into the cells"(7).
In support of above blocking, Dr. Williamson MP and colleagues at the University of Sheffield suggested, green tea Epigallocatechin gallate has a potential use as adjunctive therapy in HIV-1 infection(8) through its binding of HIV-1 glycoprotein (gp) 120 to the CD4 molecule on T cells.
References
(1) The enzymatic antioxidant system in blood and glutathione status in human immunodeficiency virus (HIV)-infected patients: effects of supplementation with selenium or beta-carotene by Delmas-Beauvieux MC1, Peuchant E, Couchouron A, Constans J, Sergeant C, Simonoff M, Pellegrin JL, Leng B, Conri C, Clerc M.(PubMed)
(2) Effect of selenium supplementation on CD4+ T-cell recovery, viral suppression and morbidity of HIV-infected patients in Rwanda: a randomized controlled trial by Kamwesiga J1, Mutabazi V, Kayumba J, Tayari JC, Uwimbabazi JC, Batanage G, Uwera G, Baziruwiha M, Ntizimira C, Murebwayire A, Haguma JP,Nyiransabimana J, Nzabandora JB, Nzamwita P, Mukazayire E; Rwanda Selenium Authorship Group.(PubMed)
(3) Plasma Selenium Concentrations Are Sufficient and Associated with Protease Inhibitor Use in Treated HIV-Infected Adults by Hileman CO1, Dirajlal-Fargo S2, Lam SK3, Kumar J3, Lacher C4, Combs GF Jr4, McComsey GA5.(PubMed)
(4) Quantitation of parvalbumin+ neurons and human immunodeficiency virus type 1 (HIV-1) regulatory gene expression in the HIV-1 transgenic rat: effects of vitamin A deficiency and morphine by Sultana S1, Li H, Puche A, Jones O, Bryant JL, Royal W.(PubMed)
(5) Effects of vitamins, including vitamin A, on HIV/AIDS patients by Mehta S1, Fawzi W.(PubMed)
(6) Natural polyphenols: potential in the prevention of sexually transmitted viral infections by Date AA1, Destache CJ2.(PubMed)
(7) How can (-)-epigallocatechin gallate from green tea prevent HIV-1 infection? Mechanistic insights from computational modeling and the implication for rational design of anti-HIV-1 entry inhibitors by Hamza A1, Zhan CG.(PubMed)
(8) Epigallocatechin gallate, the main polyphenol in green tea, binds to the T-cell receptor, CD4: Potential for HIV-1 therapy. by Williamson MP1, McCormick TG, Nance CL, Shearer WT.(PubMed)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.
Renal disease is associated to common complication in patients with human immunodeficiency virus (HIV) disease as a result of direct kidney infection with HIV or from the adverse effects of antiviral medication.
The smoothie for Reduced risk and Treatment of Acquired immunodeficiency syndrome (AIDS) associated nephropathy
Yield: 2 serving (about 8 ounce each)
1 cup Tomato
1/2 cup Brazil nut
1 cup green tea drink (Make from 4 grams of green tea, a slice of ginger and a cup of hot water lipped for 5 minute. Set aside for cooling to room temperature)
1. Place all ingredients in a blender and puree about 1 minute
2. Blend on high speed about 1 minute or until the mixture is thick and the ice is well crushed. Add more green tea drink if needed
3. Serve immediately
The dream of finding the natural ingredient for prevention and treatment of Acquired immunodeficiency syndrome (AIDS), without adverse effects in replacement of conventional medication has not been abated. Some ingredients have to discard because of not achieving the same potent results in human trials.
Scientist community may have found the smoothie(combined ingredients of garlic, olive and coconut oils) with potential and therapeutic value for reduced risk and treatment of Acquired immunodeficiency syndrome (AIDS)without adverse effects.
Human immunodeficiency virus (HIV) is a lentivirus that causes acquired immunodeficiency syndrome (AIDS) of which can lead to the progression of weakened immune system casues of infectous diseases and cancers. According to the studies, patients with human immunodeficiency virus (HIV) are asscoiated to low levels of vitamin A and selenium(1).
Selenium, a chemical element with symbol Se and antioxidant found in Brazil nut, plays an important role in protection of cell against significant impairments of antioxidative defenses induced human immunodeficiency virus (HIV) (2).
Dr. Delmas-Beauvieux MC and colleagues at the Université Bordeaux II, suggested, selenium supplementation could be of great interest in protecting cells against oxidative stress and glutathione peroxidase (GPX), and glutathione (GSH) are important in expression of natural enzymatic defense system in detoxifying hydrogen peroxide(3).
Vitamin A, a bi-polar molecule formed by bonds between carbon and hydrogen, is a fat soluble vitamin converted from beta-carotene, a powerful antioxidant. Accoridng to the The University of Maryland School of Medicine, deficiency of vitamin A in human immunodeficiency virus (HIV) infection has been associated with more progressive HIV disease(4).
Dr.Mehta S and Dr. Fawzi W. in the study of the effects of vitamins, including vitamin A, on HIV/AIDS patients, said, "periodic vitamin A supplementation of HIV-infected infants and children is beneficial in reducing all-cause mortality and morbidity and is recommended"(5).
According to the Creighton University, green tea, epigallocatechin gallate, theaflavins may be effective in prevention and treatment of sexually transmitted infections caused by HIV (human immunodeficiency virus), HSV (herpes simplex virus) and HPV (human papilloma virus)(6).
Dr. Hamza A and Dr. Zhan CG. said, "(-)-epigallocatechin gallate (EGCG) from green tea is an inhibitor blocking gp120-CD4 binding" by blocking the initial step of HIV-1 entry into the cells"(7).
In support of above blocking, Dr. Williamson MP and colleagues at the University of Sheffield suggested, green tea Epigallocatechin gallate has a potential use as adjunctive therapy in HIV-1 infection(8) through its binding of HIV-1 glycoprotein (gp) 120 to the CD4 molecule on T cells.
The Smoothie of Brazil Nut, Tomato and Green Tea may hold a key for further studies in production of a curable natural remedy for prevention and treatment of Acquired immunodeficiency syndrome (AIDS) associated nephropathy.
.
People who are at increased risk of Acquired immunodeficiency syndrome (AIDS) associated nephropathy due to family history, weaken immunity,....should drink at least one cup or more daily. People with Acquired immunodeficiency syndrome (AIDS) associated nephropathy may drink as much as they can, depending to the digestive toleration.
.
People who are at increased risk of Acquired immunodeficiency syndrome (AIDS) associated nephropathy due to family history, weaken immunity,....should drink at least one cup or more daily. People with Acquired immunodeficiency syndrome (AIDS) associated nephropathy may drink as much as they can, depending to the digestive toleration.
All Forms of Arthritis are Curable
Ovarian Cysts And PCOS Elimination
Back to General health http://kylejnorton.blogspot.ca/p/general-health.html
Back to Kyle J. Norton Home page http://kylejnorton.blogspot.ca
References
(1) The enzymatic antioxidant system in blood and glutathione status in human immunodeficiency virus (HIV)-infected patients: effects of supplementation with selenium or beta-carotene by Delmas-Beauvieux MC1, Peuchant E, Couchouron A, Constans J, Sergeant C, Simonoff M, Pellegrin JL, Leng B, Conri C, Clerc M.(PubMed)
(2) Effect of selenium supplementation on CD4+ T-cell recovery, viral suppression and morbidity of HIV-infected patients in Rwanda: a randomized controlled trial by Kamwesiga J1, Mutabazi V, Kayumba J, Tayari JC, Uwimbabazi JC, Batanage G, Uwera G, Baziruwiha M, Ntizimira C, Murebwayire A, Haguma JP,Nyiransabimana J, Nzabandora JB, Nzamwita P, Mukazayire E; Rwanda Selenium Authorship Group.(PubMed)
(3) Plasma Selenium Concentrations Are Sufficient and Associated with Protease Inhibitor Use in Treated HIV-Infected Adults by Hileman CO1, Dirajlal-Fargo S2, Lam SK3, Kumar J3, Lacher C4, Combs GF Jr4, McComsey GA5.(PubMed)
(4) Quantitation of parvalbumin+ neurons and human immunodeficiency virus type 1 (HIV-1) regulatory gene expression in the HIV-1 transgenic rat: effects of vitamin A deficiency and morphine by Sultana S1, Li H, Puche A, Jones O, Bryant JL, Royal W.(PubMed)
(5) Effects of vitamins, including vitamin A, on HIV/AIDS patients by Mehta S1, Fawzi W.(PubMed)
(6) Natural polyphenols: potential in the prevention of sexually transmitted viral infections by Date AA1, Destache CJ2.(PubMed)
(7) How can (-)-epigallocatechin gallate from green tea prevent HIV-1 infection? Mechanistic insights from computational modeling and the implication for rational design of anti-HIV-1 entry inhibitors by Hamza A1, Zhan CG.(PubMed)
(8) Epigallocatechin gallate, the main polyphenol in green tea, binds to the T-cell receptor, CD4: Potential for HIV-1 therapy. by Williamson MP1, McCormick TG, Nance CL, Shearer WT.(PubMed)
Most Common Diseases of 50plus: Pulmonary vascular disease(Respiratory disease): Pulmonary edema- Treatment In conventional & Herbal medicine perspective
Kyle J. Norton(Scholar and Master of Nutrients, all right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.
Respiratory Disease
Respiratory Disease is defined as medical conditions, affecting the breathing organ and tissues including Inflammatory lung disease, Obstructive lung diseases, Restrictive lung diseases, Respiratory tract infections, trachea, bronchi, bronchioles, alveoli, the nerves and muscles breathing, etc,.
Pulmonary vascular disease: Pulmonary edema
Pulmonary vascular disease is defined as a condition of blood flow to the lung’s artery is blocked suddenly due to a blood clot somewhere in the body, including pulmonary embolism, chronic thromboembolic disease, pulmonary arterial hypertension, pulmonary veno-occlusive disease, pulmonary arteriovenous malformations, pulmonary edema, etc.
The Treatments
A. In conventional medicine perspective
Treatment of Pulmonary edema is depending to the unlined causes of the diseases. In most cases, the disease is caused by congestive heart failure. According to A.D.A.M. Medical Encyclopedia, most cases of Pulmonary edema are almost always treated in the emergency room or hospital, sometimes in an intensive care unit (ICU), including Oxygen is given through a face mask or tiny plastic tubes are placed in the nose and a breathing tube may be placed into the windpipe (trachea) so you can be connected to a breathing machine (ventilator). The unlined causes of the disease should be diagnosis quickly and treated accordingly. Certain medications may be prescribed such as diuretics to remove excess fluids from the body and medicines to strengthen the heart muscle, control the heartbeat, or relieve pressure on the heart(62).
B. In Herbal medicine perspective
1. Sea buckthorn
Sea buckthorn (Hippophaë rhamnoides L.) is a rich source of flavonols, especially isorhamnetin. Most prospective cohort studies have indicated some degree of inverse association between flavonoid intake and coronary heart disease.
2. Astragalus
Astragalus (Astragalus onobrychis), also known as Huang Qi in traditional Chinese medicine, is a genus of small shrubs, belonging to the legume family Fabaceae. The herb has been used in traditional herbal medicine in boosting and stimulating the immune system, as a diuretic, to treat shortness of breath, general weakness, and lack of appetite, colds, flu, stomach ulcers, diabetes, etc.
a. Congestive heart failure
In a study of Sixty-two in-patients with CHF (congestive heart failure), whose heart function belonged to NYHA grade II-IV with Astragalus Injection (AI),conducted by Huazhong University of Science and Technology, posted in PubMed(63), researchers found that astragalus Injection could improve the immune function of CHF patients, and can be taken as an important auxiliary treatment for CHF.
b. Atherosclerosis
Extract of Astragalus, Radix Codonopsis and Cortex Lycii, reduces the risk of Atherosclerosis by suppressing the low-density lipoprotein (LDL) oxidation and inhibiting vascular smooth muscle cell migration, according to the study of “Suppression of low-density lipoprotein oxidation, vascular smooth muscle cell proliferation and migration by a herbal extract of Radix Astragali, Radix Codonopsis and Cortex Lycii” by Chan JY, Koon JC, Leung PC, Che CT, Fung KP., posted in PubMed(64).
c. Heart diseases
One optimal dose of DHEA or Astragalus can reduce the condition of heart disease? according to the study of “Organ representation areas of different internal organs localized on the eyebrows & eyelids by the Bi-Digital O-Ring Test electromagnetic resonance phenomenon between 2 identical molecules–Part I: Detection of increased markers for cancer & heart disease from white hairs on the eyebrows and marked decrease in the markers after taking one optimal dose of DHEA” by Omura Y., posted in PubMed(65)
d. Hypertension
flavonoid (TF), extracted from the seed of Astragalus have shown the properties of lowering blood pressure in both in both renal hypertensive rats (RHR) and spontaneously hypertensive rats (SHR) according to the study of “Antihypertensive effect of total flavonoid fraction of Astragalus complanatus in hypertensive rats” by Li JX, Xue B, Chai Q, Liu ZX, Zhao AP, Chen LB., posted in PubMed(66)
3. Bromelain
Bromelain, a proteolytic enzymes found in pineapples (Ananas comosus) has been used in traditional medicine as inflammatory agent and to treat pains, strains, and muscle aches and pains and ease back pain and chronic joint pain, skin diseases, etc.
a. Bromelain in cardiovascular diseases
In the review out of Out of 223 papers retrieved, 6 papers met the inclusion criteria(Randomised controlled trials (RCTs), human studies, animal studies and experimental studies related to bromelain for CVDs. Data extraction and analysis: The quality assessment of all the selected studies was conducted by the authors. Data from 3 animal trials and 3 human trials were included in the review. Data collected included: type of trial, drug dosage, duration, outcome measures, characteristics of bromelain used, significance of results and conclusion),bromelain could be used for treating acute thrombophlebitis, as it decreases aggregation of blood platelets, has a cardio-protective effect, ameliorates rejection-induced arterial wall remodelling, prevents thrombin-induced human platelet aggregation as well as reduces thrombus formation, according to the study of “A review of the use of bromelain in cardiovascular diseases” by Ley CM, Tsiami A, Ni Q, Robinson N., posted in PubMed(67)
b. Renal diseases
Bromelain proteolytic enzymes has improved proteinuria and urinary TGF-beta 1 excretion, as well as the severity of tubulointerstitial fibrosis without signs of toxicity, according to the study of “The effect of oral protease administration in the rat remnant kidney model” Sebeková K, Dämmrich J, Krivosíková Z, Heidland A.” by posted in PubMed(68).
4. Garlic
Garlic (Allium sativum) is a species in the onion genus, belonging to family Amaryllidaceae, native to central Asia. It has been used popularly in traditional and Chinese medicine in treating common cold and flu to the Plague, blood pressure cholesterol levels, natural antibiotic, etc.
a. Blood pressure
In the assessment of garlic extract and its effect of hypertension. found that Agedgarlic extract was generally well tolerated and acceptability of trial treatment was high (92%) and aged garlic extract is superior to placebo in lowering systolic blood pressure similarly to current first line medications in patients with treated but uncontrolled hypertension, according to “Aged garlicextract lowers blood pressure in patients with treated but uncontrolled hypertension: a randomised controlled trial” by Ried K, Frank OR, Stocks NP.(69)
b. Atherosclerosis
In the demonstration of aged garlic extract therapy with supplements (AGE+S) and theirs effect on cardiovascular diseases found that CAC progression was significantly lower and TR significantly higher in the AGE+S compared to the placebo group after adjustment of cardiovascular risk factors (p<0.05). Total cholesterol, LDL-C, homocysteine, IgG and IgM autoantibodies to MDA-LDL and apoB-immune complexes were decreased, whereas HDL, OxPL/apoB, and Lp (a) were significantly increased in AGE+S to placebo and concluded that AGE+S is associated with a favorable improvement in oxidative biomarkers, vascular function, and reduced progression of atherosclerosis., according to “Agedgarlicextract supplemented with B vitamins, folic acid and L-arginine retards the progression of subclinical atherosclerosis: a randomized clinical trial” by Budoff MJ, Ahmadi N, Gul KM, Liu ST, Flores FR, Tiano J, Takasu J, Miller E, Tsimikas S.(70).
c. . Cardiovascular diseases
In the review of the experimental and clinical studies confirm that the ancient experience with beneficial effects of garlic holds validity even in prevention ofcardiovascular disorders and other metabolic ills, indicated that Garlic-derived organic polysulfides are converted by erythrocytes into hydrogen sulfide which relaxes vascular smooth muscle, induces vasodilation of blood vessels, and significantly reduces blood pressure. There are data on potential ability of garlic to inhibit the rate of progression of coronary calcification. Garlic as a dietary component appears to hold promise to reduce the risk of cardiovascular disease(Fig. 2, Ref. 46), according to “Garlic (Allium sativum L.) and cardiovascular diseases” by Ginter E, Simko V.(71)
All Forms of Arthritis are Curable
You Can Eliminate Osteoarthritis
By addressing the Underlying Causes through Clinical Trials and Studies
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to General health http://kylejnorton.blogspot.ca/p/general-health.html
Back to Kyle J. Norton Home page http://kylejnorton.blogspot.ca
Sources
(a) http://www.ncbi.nlm.nih.gov/pubmed/19739476
(62) http://www.ncbi.nlm.nih.gov/pubmedhealth/PMH0001195/
(63) http://www.ncbi.nlm.nih.gov/pubmed/16968106
(63) http://www.ncbi.nlm.nih.gov/pubmed/12800417
(64) http://www.ncbi.nlm.nih.gov/pubmed/21513503
(65) http://www.ncbi.nlm.nih.gov/pubmed/19301629
(66) http://www.ncbi.nlm.nih.gov/pubmed/16201455
(67) http://www.ncbi.nlm.nih.gov/pubmed/21749819
(68) http://www.ncbi.nlm.nih.gov/pubmed/10639701
(69) http://www.ncbi.nlm.nih.gov/pubmed/20594781
(70) http://www.ncbi.nlm.nih.gov/pubmed/19573556
(71) http://www.ncbi.nlm.nih.gov/pubmed/21033626
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.
Respiratory Disease
Respiratory Disease is defined as medical conditions, affecting the breathing organ and tissues including Inflammatory lung disease, Obstructive lung diseases, Restrictive lung diseases, Respiratory tract infections, trachea, bronchi, bronchioles, alveoli, the nerves and muscles breathing, etc,.
Pulmonary vascular disease: Pulmonary edema
Pulmonary vascular disease is defined as a condition of blood flow to the lung’s artery is blocked suddenly due to a blood clot somewhere in the body, including pulmonary embolism, chronic thromboembolic disease, pulmonary arterial hypertension, pulmonary veno-occlusive disease, pulmonary arteriovenous malformations, pulmonary edema, etc.
Pulmonary edema is defined as a condition of fluid accumulation in the air spaces and parenchyma of the lungs of that can lead to difficult of breathing and respiratory failure.
A. In conventional medicine perspective
Treatment of Pulmonary edema is depending to the unlined causes of the diseases. In most cases, the disease is caused by congestive heart failure. According to A.D.A.M. Medical Encyclopedia, most cases of Pulmonary edema are almost always treated in the emergency room or hospital, sometimes in an intensive care unit (ICU), including Oxygen is given through a face mask or tiny plastic tubes are placed in the nose and a breathing tube may be placed into the windpipe (trachea) so you can be connected to a breathing machine (ventilator). The unlined causes of the disease should be diagnosis quickly and treated accordingly. Certain medications may be prescribed such as diuretics to remove excess fluids from the body and medicines to strengthen the heart muscle, control the heartbeat, or relieve pressure on the heart(62).
B. In Herbal medicine perspective
1. Sea buckthorn
Sea buckthorn (Hippophaë rhamnoides L.) is a rich source of flavonols, especially isorhamnetin. Most prospective cohort studies have indicated some degree of inverse association between flavonoid intake and coronary heart disease.
2. Astragalus
Astragalus (Astragalus onobrychis), also known as Huang Qi in traditional Chinese medicine, is a genus of small shrubs, belonging to the legume family Fabaceae. The herb has been used in traditional herbal medicine in boosting and stimulating the immune system, as a diuretic, to treat shortness of breath, general weakness, and lack of appetite, colds, flu, stomach ulcers, diabetes, etc.
a. Congestive heart failure
In a study of Sixty-two in-patients with CHF (congestive heart failure), whose heart function belonged to NYHA grade II-IV with Astragalus Injection (AI),conducted by Huazhong University of Science and Technology, posted in PubMed(63), researchers found that astragalus Injection could improve the immune function of CHF patients, and can be taken as an important auxiliary treatment for CHF.
b. Atherosclerosis
Extract of Astragalus, Radix Codonopsis and Cortex Lycii, reduces the risk of Atherosclerosis by suppressing the low-density lipoprotein (LDL) oxidation and inhibiting vascular smooth muscle cell migration, according to the study of “Suppression of low-density lipoprotein oxidation, vascular smooth muscle cell proliferation and migration by a herbal extract of Radix Astragali, Radix Codonopsis and Cortex Lycii” by Chan JY, Koon JC, Leung PC, Che CT, Fung KP., posted in PubMed(64).
c. Heart diseases
One optimal dose of DHEA or Astragalus can reduce the condition of heart disease? according to the study of “Organ representation areas of different internal organs localized on the eyebrows & eyelids by the Bi-Digital O-Ring Test electromagnetic resonance phenomenon between 2 identical molecules–Part I: Detection of increased markers for cancer & heart disease from white hairs on the eyebrows and marked decrease in the markers after taking one optimal dose of DHEA” by Omura Y., posted in PubMed(65)
d. Hypertension
flavonoid (TF), extracted from the seed of Astragalus have shown the properties of lowering blood pressure in both in both renal hypertensive rats (RHR) and spontaneously hypertensive rats (SHR) according to the study of “Antihypertensive effect of total flavonoid fraction of Astragalus complanatus in hypertensive rats” by Li JX, Xue B, Chai Q, Liu ZX, Zhao AP, Chen LB., posted in PubMed(66)
3. Bromelain
Bromelain, a proteolytic enzymes found in pineapples (Ananas comosus) has been used in traditional medicine as inflammatory agent and to treat pains, strains, and muscle aches and pains and ease back pain and chronic joint pain, skin diseases, etc.
a. Bromelain in cardiovascular diseases
In the review out of Out of 223 papers retrieved, 6 papers met the inclusion criteria(Randomised controlled trials (RCTs), human studies, animal studies and experimental studies related to bromelain for CVDs. Data extraction and analysis: The quality assessment of all the selected studies was conducted by the authors. Data from 3 animal trials and 3 human trials were included in the review. Data collected included: type of trial, drug dosage, duration, outcome measures, characteristics of bromelain used, significance of results and conclusion),bromelain could be used for treating acute thrombophlebitis, as it decreases aggregation of blood platelets, has a cardio-protective effect, ameliorates rejection-induced arterial wall remodelling, prevents thrombin-induced human platelet aggregation as well as reduces thrombus formation, according to the study of “A review of the use of bromelain in cardiovascular diseases” by Ley CM, Tsiami A, Ni Q, Robinson N., posted in PubMed(67)
b. Renal diseases
Bromelain proteolytic enzymes has improved proteinuria and urinary TGF-beta 1 excretion, as well as the severity of tubulointerstitial fibrosis without signs of toxicity, according to the study of “The effect of oral protease administration in the rat remnant kidney model” Sebeková K, Dämmrich J, Krivosíková Z, Heidland A.” by posted in PubMed(68).
4. Garlic
Garlic (Allium sativum) is a species in the onion genus, belonging to family Amaryllidaceae, native to central Asia. It has been used popularly in traditional and Chinese medicine in treating common cold and flu to the Plague, blood pressure cholesterol levels, natural antibiotic, etc.
a. Blood pressure
In the assessment of garlic extract and its effect of hypertension. found that Agedgarlic extract was generally well tolerated and acceptability of trial treatment was high (92%) and aged garlic extract is superior to placebo in lowering systolic blood pressure similarly to current first line medications in patients with treated but uncontrolled hypertension, according to “Aged garlicextract lowers blood pressure in patients with treated but uncontrolled hypertension: a randomised controlled trial” by Ried K, Frank OR, Stocks NP.(69)
b. Atherosclerosis
In the demonstration of aged garlic extract therapy with supplements (AGE+S) and theirs effect on cardiovascular diseases found that CAC progression was significantly lower and TR significantly higher in the AGE+S compared to the placebo group after adjustment of cardiovascular risk factors (p<0.05). Total cholesterol, LDL-C, homocysteine, IgG and IgM autoantibodies to MDA-LDL and apoB-immune complexes were decreased, whereas HDL, OxPL/apoB, and Lp (a) were significantly increased in AGE+S to placebo and concluded that AGE+S is associated with a favorable improvement in oxidative biomarkers, vascular function, and reduced progression of atherosclerosis., according to “Agedgarlicextract supplemented with B vitamins, folic acid and L-arginine retards the progression of subclinical atherosclerosis: a randomized clinical trial” by Budoff MJ, Ahmadi N, Gul KM, Liu ST, Flores FR, Tiano J, Takasu J, Miller E, Tsimikas S.(70).
c. . Cardiovascular diseases
In the review of the experimental and clinical studies confirm that the ancient experience with beneficial effects of garlic holds validity even in prevention ofcardiovascular disorders and other metabolic ills, indicated that Garlic-derived organic polysulfides are converted by erythrocytes into hydrogen sulfide which relaxes vascular smooth muscle, induces vasodilation of blood vessels, and significantly reduces blood pressure. There are data on potential ability of garlic to inhibit the rate of progression of coronary calcification. Garlic as a dietary component appears to hold promise to reduce the risk of cardiovascular disease(Fig. 2, Ref. 46), according to “Garlic (Allium sativum L.) and cardiovascular diseases” by Ginter E, Simko V.(71)
All Forms of Arthritis are Curable
You Can Eliminate Osteoarthritis
By addressing the Underlying Causes through Clinical Trials and Studies
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to General health http://kylejnorton.blogspot.ca/p/general-health.html
Back to Kyle J. Norton Home page http://kylejnorton.blogspot.ca
Sources
(a) http://www.ncbi.nlm.nih.gov/pubmed/19739476
(62) http://www.ncbi.nlm.nih.gov/pubmedhealth/PMH0001195/
(63) http://www.ncbi.nlm.nih.gov/pubmed/16968106
(63) http://www.ncbi.nlm.nih.gov/pubmed/12800417
(64) http://www.ncbi.nlm.nih.gov/pubmed/21513503
(65) http://www.ncbi.nlm.nih.gov/pubmed/19301629
(66) http://www.ncbi.nlm.nih.gov/pubmed/16201455
(67) http://www.ncbi.nlm.nih.gov/pubmed/21749819
(68) http://www.ncbi.nlm.nih.gov/pubmed/10639701
(69) http://www.ncbi.nlm.nih.gov/pubmed/20594781
(70) http://www.ncbi.nlm.nih.gov/pubmed/19573556
(71) http://www.ncbi.nlm.nih.gov/pubmed/21033626
Most Common Disease of50plus: The Clinical trials and Studies of Musculo-Skeletal disorders(MSDs) - Osteoarthritis: Treatment In herbal and traditional Chinese medicine - Top vitamins for osteoarthritis
Kyle J. Norton (Scholar)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.
Musculoskeletal disorders (MSDs) are medical condition mostly caused by work related occupations and working environment, affecting patients’ muscles, joints, tendons, ligaments and nerves and developing over time. A community sample of 73 females and 32 males aged 85 and over underwent a standardised examination at home. Musculoskeletal pain was reported by 57% of those interviewed. A major restriction of joint movement range was frequent in the shoulder but uncommon in other joints(1).
Types of Musculo-Skeletal disorders in elder(2)
1. Osteoarthritis
2. Gout
3. Rheumatoid Arthritis
4. Polymalagia Arthritis
5. Cervical myleopathy and spinal canal stenosis
6. Osteoporosis
7. Low back pain
8. Fibromyalgia
Osteoarthritis
Osteoarthritis (OA), a form of arthritis, is defined as a condition of as a result of aging causes of wear and tear on a joint, affecting over 25 million people in the United States in alone. University of Porto Medical School indicated that one must understand the differences in prevalence and incidence estimates of osteoarthritis (OA), according to case definition, in knee, hip and hand joints(3).
The characteristics of osteoarthritis are aching pain(5), stiffness(6), or difficulty of moving the joint or joints(7). The pain usually gets worse in change of weather, at night and in the advanced diseases, the pain can occur even at rest(8). Today management of osteoarthritis (OA) focuses on pain relief and improved physical function through pharmacological, non pharmacological, and surgical treatments(4).
The Treatment
B. In herbal and traditional Chinese medicine perspective
B.3. The Preventive Minerals and Vitamins
2. Top vitamins for osteoarthritis
According to Anatomisches Institut der CAU zu Kiel, Olshausenstr, diet supplemented with the vitamins E, C, A, B6, B2, play an important role in prevention or therapy of mechanically induced OA, due to the effects of their antioxidant activity(335).
3.1. Vitamin A
Intake of free radical scavengers and antioxidants such as carotenoids have been known for influence the development and progression of osteoarthritis (OA)(339), according to the Nagoya University Graduate School of Medicine, high serum values of beta-/gamma-tocopherols (Vitamin A) were found to be significantly associated with a reduced risk of OR for radiographic kneeosteoarthritis(338). In Race differentiation, according to the University of North Carolina at Chapel Hill, radiographic kneeosteoarthritis and tocopherol isoforms are complex and may vary by ethnicity and sex(340).
3.2. Vitamin C
In a case-control study enrolled 180 knee osteoarthritis (KOA), Low intake of dietary vitamin D and vitamin C has shown to induced a high risk factor of KOA(344)Vitamin C as an antioxidant has shown to reduce oxidative stress causes of dysfunction in chondrocytes and articular cartilage degradation in patient with OA(342) induced by H2O2 by regulating multiple regulatory pathways(341). Intake of vitamin C supplement has reduced risk of OA incidence but not in decreased progression of knee in patient with OA(343).
3.3. Vitamin E
In comparison of the effectiveness of vitamin E and B vitamin in patient with knee OA, Dr. Dehghan M said "decrease in total pain severity was reported higher in B vitamin group than E vitamin"(336).
In the study of the pro-oxidant and antioxidant status in patient with OA, high levels of serum of vitamin E is associated to reduced risk of oxidative stress causes of osteoarthritis through regulation in response to increased oxidative stress(345). The study of total otal cartilage degeneration in rat models, also insisted that Vitamin E expressed not only in hondroprotective activity but also exhibited a beneficial effects of HA on articular cartilage(346).
Unfortunately, a double blind, placebo controlled trial, 136 patients with knee OA from American College of Rheumatology clinical and radiographic criteria did not support the beneficial effect of Vitamin E in the management of knee OA, in improved cartilage volume loss or symptoms(347).
3.4.Vitamin D
Vitamin D is associated to the development and progression of osteoarthritis, as l dietary vitamin D intake increases the risk of progression of knee ROA, effecting the bone density(348). Vitamin D deficiency also has found to induced risk of progression(349) and worsening of knee osteoarthritis in patient(350). According to the study of a total of 880 randomly selected subjects (mean age 61 years [range 51-79 years], 50% women) at baseline, conducted by the University of Tasmania, sunlight exposure and serum 25(OH)D levels are found to associate with decreased knee cartilage loss(351).
In deed, Other vitamin such as vitamin D is found to modify disease progression in knee OA, through
reduce knee pain, loss of knee cartilage volume, risk knee structural abnormalities and strengthen lower limb muscle strength(337).
3.5. B vitamin
According to the Shahrekord University of Medical Science, in the studyof mean score of WOMAC questionnaire at VASs of knee pain, total pain severity, knee joint stiffness, showed that the B vitamin decrease stiffness in knee joint(352). In deed, high consumption of the mixture of B vitamins and diclofenac have been found effectively in reduced pain and inflammation for patient with osteoarthritis and used in a total knee arthroplasty(353).
Arthritis Is Curable
You Can Eliminate Osteoarthritis
By addressing the Underlying Causes through Clinical Trials and Studies
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Super foods Library, Eat Yourself Healthy With The Best of the Best Nature Has to Offer recommended by Kyle J. Norton
Back to Kyle J. Norton Home page http://kylejnorton.blogspot.ca
References
(1) Prevalence of rheumatic symptoms, rheumatoid arthritis, ankylosing spondylitis, and gout in Shanghai, China: a COPCORD study by Dai SM1, Han XH, Zhao DB, Shi YQ, Liu Y, Meng JM.(PubMed)
(2) Musculoskeletal Disorders in the Elderly by Ramon Gheno, Juan M. Cepparo, Cristina E. Rosca,1 and Anne Cotten(PMC)
(3) The effect of osteoarthritis definition on prevalence and incidence estimates: a systematic review by Pereira D1, Peleteiro B, Araújo J, Branco J, Santos RA, Ramos E.(PubMed)
(4) Effect of therapeutic aquatic exercise on symptoms and function associated with lower limb osteoarthritis: systematic review with meta-analysis by Waller B1, Ogonowska-Slodownik A2, Vitor M3, Lambeck J4, Daly D5, Kujala UM6, Heinonen A7.(PubMed)
(5) Effects of therapeutic ultrasound on pain, physical functions and safety outcomes in patients with kneeosteoarthritis: A systematic review and meta-analysis by Zhang C1, Xie Y2, Luo X3, Ji Q3, Lu C3, He C4, Wang P3.(PubMed)
(6) Oral intake of purple passion fruit peel extract reduces pain and stiffness and improves physical function in adult patients with knee osteoarthritis by Farid R1, Rezaieyazdi Z, Mirfeizi Z, Hatef MR, Mirheidari M, Mansouri H, Esmaelli H, Bentley G, Lu Y, Foo Y, Watson RR.(PubMed)
(7) Functional ability, mobility, and pain before and after knee replacement in patients aged 75 and older: a cross-sectional study by Limnell K1, Jämsen E, Huhtala H, Jäntti P, Puolakka T, Jylhä M.(PubMed)
(8) The symptoms of OA and the genesis of pain by David J. Hunter, MBBS PhD,1,2 Jason J. McDougall, BSc PhD,3 and Francis J. Keefe4(PubMed)
(335) Dietary vitamins and selenium diminish the development of mechanically induced osteoarthritis and increase the expression of antioxidative enzymes in the knee joint of STR/1N mice. by Kurz B1, Jost B, Schünke M.(PubMed)
(336) Comparative effectiveness of B and e vitamins with diclofenac in reducing pain due to osteoarthritis of the knee by Dehghan M1(PubMed).
(337) Vitamin D supplementation in the management of knee osteoarthritis: study protocol for a randomized controlled trial by Cao Y1, Jones G, Cicuttini F, Winzenberg T, Wluka A, Sharman J, Nguo K, Ding C.(PubMed)
(338) Association of serum carotenoids, retinol, and tocopherols with radiographic knee osteoarthritis: possible risk factors in rural Japanese inhabitants by Seki T1, Hasegawa Y, Yamaguchi J, Kanoh T, Ishiguro N, Tsuboi M, Ito Y, Hamajima N, Suzuki K.(PubMed)
(339) Serum carotenoids and radiographic knee osteoarthritis: the Johnston County Osteoarthritis Project by De Roos AJ1, Arab L, Renner JB, Craft N, Luta G, Helmick CG, Hochberg MC, Jordan JM.(PubMed)
(340) A case-control study of serum tocopherol levels and the alpha- to gamma-tocopherol ratio in radiographic kneeosteoarthritis: the Johnston County Osteoarthritis Project by Jordan JM1, De Roos AJ, Renner JB, Luta G, Cohen A, Craft N, Helmick CG, Hochberg MC, Arab L.(PubMed)
(341) Ascorbic acid provides protection for human chondrocytes against oxidative stress by Chang Z1, Huo L1, Li P1, Wu Y1, Zhang P1.(PubMed)
(342) Potential involvement of oxidative stress in cartilage senescence and development of osteoarthritis: oxidative stress induces chondrocyte telomere instability and downregulation of chondrocyte function by Yudoh K1, Nguyen vT, Nakamura H, Hongo-Masuko K, Kato T, Nishioka K.(PubMed)
(343) Osteoarthritis and nutrition. From nutraceuticals to functional foods: a systematic review of the scientific evidenc by Laurent G Ameye
1 and Winnie SS Chee1(PMC)
(344) Elucidation of dietary risk factors in osteoarthritis knee—a case-control study by Sanghi D1, Mishra A, Sharma AC, Raj S, Mishra R, Kumari R, Natu SM, Agarwal S, Srivastava RN.(PubMed)
(345) Status of lipid peroxidation, glutathione, ascorbic acid, vitamin E and antioxidant enzymes in patients withosteoarthritis by Surapaneni KM1, Venkataramana G.(PubMed)
(346) Intra-articular hyaluronate, tenoxicam and vitamin E in a rat model of osteoarthritis: evaluation and comparison of chondroprotective efficacy by Ozkan FU1, Uzer G2, Türkmen I3, Yildiz Y3, Senol S4, Ozkan K3, Turkmensoy F3, Ramadan S5, Aktas I1(PubMed)
(347) Supplementary vitamin E does not affect the loss of cartilage volume in knee osteoarthritis: a 2 year double blind randomized placebo controlled study by Wluka AE1, Stuckey S, Brand C, Cicuttini FM.(PubMed)
(348) Vitamin D status, bone mineral density, and the development of radiographic osteoarthritis of the knee: The Rotterdam Study by Bergink AP1, Uitterlinden AG, Van Leeuwen JP, Buurman CJ, Hofman A, Verhaar JA, Pols HA.(PubMed)
(349) Vitamin D deficiency is associated with progression of knee osteoarthritis by Zhang FF1, Driban JB2, Lo GH3, Price LL4, Booth S5, Eaton CB6, Lu B7, Nevitt M8, Jackson B9, Garganta C10, Hochberg MC11, Kwoh K12, McAlindon TE2.(PubMed)
(350) Low levels of vitamin D and worsening of knee osteoarthritis: results of two longitudinal studies by Felson DT1, Niu J, Clancy M, Aliabadi P, Sack B, Guermazi A, Hunter DJ, Amin S, Rogers G, Booth SL.(PubMed)
(351) Serum levels of vitamin D, sunlight exposure, and knee cartilage loss in older adults: the Tasmanian older adult cohort study by Ding C1, Cicuttini F, Parameswaran V, Burgess J, Quinn S, Jones G.(PubMed)
(352) Comparative effectiveness of B and e vitamins with diclofenac in reducing pain due to osteoarthritis of the knee by Dehghan M1.(PubMed)
(353) B-vitamin mixture improves the analgesic effect of diclofenac in patients with osteoarthritis: a double blind study by Magaña-Villa MC1, Rocha-González HI, Fernández del Valle-Laisequilla C, Granados-Soto V, Rodríguez-Silverio J, Flores-Murrieta FJ, Carrasco-Portugal MC,Reyes-García JG.(PubMed)
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Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.
Musculoskeletal disorders (MSDs) are medical condition mostly caused by work related occupations and working environment, affecting patients’ muscles, joints, tendons, ligaments and nerves and developing over time. A community sample of 73 females and 32 males aged 85 and over underwent a standardised examination at home. Musculoskeletal pain was reported by 57% of those interviewed. A major restriction of joint movement range was frequent in the shoulder but uncommon in other joints(1).
Types of Musculo-Skeletal disorders in elder(2)
1. Osteoarthritis
2. Gout
3. Rheumatoid Arthritis
4. Polymalagia Arthritis
5. Cervical myleopathy and spinal canal stenosis
6. Osteoporosis
7. Low back pain
8. Fibromyalgia
Osteoarthritis
Osteoarthritis (OA), a form of arthritis, is defined as a condition of as a result of aging causes of wear and tear on a joint, affecting over 25 million people in the United States in alone. University of Porto Medical School indicated that one must understand the differences in prevalence and incidence estimates of osteoarthritis (OA), according to case definition, in knee, hip and hand joints(3).
The characteristics of osteoarthritis are aching pain(5), stiffness(6), or difficulty of moving the joint or joints(7). The pain usually gets worse in change of weather, at night and in the advanced diseases, the pain can occur even at rest(8). Today management of osteoarthritis (OA) focuses on pain relief and improved physical function through pharmacological, non pharmacological, and surgical treatments(4).
The Treatment
B. In herbal and traditional Chinese medicine perspective
B.3. The Preventive Minerals and Vitamins
2. Top vitamins for osteoarthritis
According to Anatomisches Institut der CAU zu Kiel, Olshausenstr, diet supplemented with the vitamins E, C, A, B6, B2, play an important role in prevention or therapy of mechanically induced OA, due to the effects of their antioxidant activity(335).
3.1. Vitamin A
Intake of free radical scavengers and antioxidants such as carotenoids have been known for influence the development and progression of osteoarthritis (OA)(339), according to the Nagoya University Graduate School of Medicine, high serum values of beta-/gamma-tocopherols (Vitamin A) were found to be significantly associated with a reduced risk of OR for radiographic kneeosteoarthritis(338). In Race differentiation, according to the University of North Carolina at Chapel Hill, radiographic kneeosteoarthritis and tocopherol isoforms are complex and may vary by ethnicity and sex(340).
3.2. Vitamin C
In a case-control study enrolled 180 knee osteoarthritis (KOA), Low intake of dietary vitamin D and vitamin C has shown to induced a high risk factor of KOA(344)Vitamin C as an antioxidant has shown to reduce oxidative stress causes of dysfunction in chondrocytes and articular cartilage degradation in patient with OA(342) induced by H2O2 by regulating multiple regulatory pathways(341). Intake of vitamin C supplement has reduced risk of OA incidence but not in decreased progression of knee in patient with OA(343).
3.3. Vitamin E
In comparison of the effectiveness of vitamin E and B vitamin in patient with knee OA, Dr. Dehghan M said "decrease in total pain severity was reported higher in B vitamin group than E vitamin"(336).
In the study of the pro-oxidant and antioxidant status in patient with OA, high levels of serum of vitamin E is associated to reduced risk of oxidative stress causes of osteoarthritis through regulation in response to increased oxidative stress(345). The study of total otal cartilage degeneration in rat models, also insisted that Vitamin E expressed not only in hondroprotective activity but also exhibited a beneficial effects of HA on articular cartilage(346).
Unfortunately, a double blind, placebo controlled trial, 136 patients with knee OA from American College of Rheumatology clinical and radiographic criteria did not support the beneficial effect of Vitamin E in the management of knee OA, in improved cartilage volume loss or symptoms(347).
3.4.Vitamin D
Vitamin D is associated to the development and progression of osteoarthritis, as l dietary vitamin D intake increases the risk of progression of knee ROA, effecting the bone density(348). Vitamin D deficiency also has found to induced risk of progression(349) and worsening of knee osteoarthritis in patient(350). According to the study of a total of 880 randomly selected subjects (mean age 61 years [range 51-79 years], 50% women) at baseline, conducted by the University of Tasmania, sunlight exposure and serum 25(OH)D levels are found to associate with decreased knee cartilage loss(351).
In deed, Other vitamin such as vitamin D is found to modify disease progression in knee OA, through
reduce knee pain, loss of knee cartilage volume, risk knee structural abnormalities and strengthen lower limb muscle strength(337).
3.5. B vitamin
According to the Shahrekord University of Medical Science, in the studyof mean score of WOMAC questionnaire at VASs of knee pain, total pain severity, knee joint stiffness, showed that the B vitamin decrease stiffness in knee joint(352). In deed, high consumption of the mixture of B vitamins and diclofenac have been found effectively in reduced pain and inflammation for patient with osteoarthritis and used in a total knee arthroplasty(353).
Arthritis Is Curable
You Can Eliminate Osteoarthritis
By addressing the Underlying Causes through Clinical Trials and Studies
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
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References
(1) Prevalence of rheumatic symptoms, rheumatoid arthritis, ankylosing spondylitis, and gout in Shanghai, China: a COPCORD study by Dai SM1, Han XH, Zhao DB, Shi YQ, Liu Y, Meng JM.(PubMed)
(2) Musculoskeletal Disorders in the Elderly by Ramon Gheno, Juan M. Cepparo, Cristina E. Rosca,1 and Anne Cotten(PMC)
(3) The effect of osteoarthritis definition on prevalence and incidence estimates: a systematic review by Pereira D1, Peleteiro B, Araújo J, Branco J, Santos RA, Ramos E.(PubMed)
(4) Effect of therapeutic aquatic exercise on symptoms and function associated with lower limb osteoarthritis: systematic review with meta-analysis by Waller B1, Ogonowska-Slodownik A2, Vitor M3, Lambeck J4, Daly D5, Kujala UM6, Heinonen A7.(PubMed)
(5) Effects of therapeutic ultrasound on pain, physical functions and safety outcomes in patients with kneeosteoarthritis: A systematic review and meta-analysis by Zhang C1, Xie Y2, Luo X3, Ji Q3, Lu C3, He C4, Wang P3.(PubMed)
(6) Oral intake of purple passion fruit peel extract reduces pain and stiffness and improves physical function in adult patients with knee osteoarthritis by Farid R1, Rezaieyazdi Z, Mirfeizi Z, Hatef MR, Mirheidari M, Mansouri H, Esmaelli H, Bentley G, Lu Y, Foo Y, Watson RR.(PubMed)
(7) Functional ability, mobility, and pain before and after knee replacement in patients aged 75 and older: a cross-sectional study by Limnell K1, Jämsen E, Huhtala H, Jäntti P, Puolakka T, Jylhä M.(PubMed)
(8) The symptoms of OA and the genesis of pain by David J. Hunter, MBBS PhD,1,2 Jason J. McDougall, BSc PhD,3 and Francis J. Keefe4(PubMed)
(335) Dietary vitamins and selenium diminish the development of mechanically induced osteoarthritis and increase the expression of antioxidative enzymes in the knee joint of STR/1N mice. by Kurz B1, Jost B, Schünke M.(PubMed)
(336) Comparative effectiveness of B and e vitamins with diclofenac in reducing pain due to osteoarthritis of the knee by Dehghan M1(PubMed).
(337) Vitamin D supplementation in the management of knee osteoarthritis: study protocol for a randomized controlled trial by Cao Y1, Jones G, Cicuttini F, Winzenberg T, Wluka A, Sharman J, Nguo K, Ding C.(PubMed)
(338) Association of serum carotenoids, retinol, and tocopherols with radiographic knee osteoarthritis: possible risk factors in rural Japanese inhabitants by Seki T1, Hasegawa Y, Yamaguchi J, Kanoh T, Ishiguro N, Tsuboi M, Ito Y, Hamajima N, Suzuki K.(PubMed)
(339) Serum carotenoids and radiographic knee osteoarthritis: the Johnston County Osteoarthritis Project by De Roos AJ1, Arab L, Renner JB, Craft N, Luta G, Helmick CG, Hochberg MC, Jordan JM.(PubMed)
(340) A case-control study of serum tocopherol levels and the alpha- to gamma-tocopherol ratio in radiographic kneeosteoarthritis: the Johnston County Osteoarthritis Project by Jordan JM1, De Roos AJ, Renner JB, Luta G, Cohen A, Craft N, Helmick CG, Hochberg MC, Arab L.(PubMed)
(341) Ascorbic acid provides protection for human chondrocytes against oxidative stress by Chang Z1, Huo L1, Li P1, Wu Y1, Zhang P1.(PubMed)
(342) Potential involvement of oxidative stress in cartilage senescence and development of osteoarthritis: oxidative stress induces chondrocyte telomere instability and downregulation of chondrocyte function by Yudoh K1, Nguyen vT, Nakamura H, Hongo-Masuko K, Kato T, Nishioka K.(PubMed)
(343) Osteoarthritis and nutrition. From nutraceuticals to functional foods: a systematic review of the scientific evidenc by Laurent G Ameye
1 and Winnie SS Chee1(PMC)(344) Elucidation of dietary risk factors in osteoarthritis knee—a case-control study by Sanghi D1, Mishra A, Sharma AC, Raj S, Mishra R, Kumari R, Natu SM, Agarwal S, Srivastava RN.(PubMed)
(345) Status of lipid peroxidation, glutathione, ascorbic acid, vitamin E and antioxidant enzymes in patients withosteoarthritis by Surapaneni KM1, Venkataramana G.(PubMed)
(346) Intra-articular hyaluronate, tenoxicam and vitamin E in a rat model of osteoarthritis: evaluation and comparison of chondroprotective efficacy by Ozkan FU1, Uzer G2, Türkmen I3, Yildiz Y3, Senol S4, Ozkan K3, Turkmensoy F3, Ramadan S5, Aktas I1(PubMed)
(347) Supplementary vitamin E does not affect the loss of cartilage volume in knee osteoarthritis: a 2 year double blind randomized placebo controlled study by Wluka AE1, Stuckey S, Brand C, Cicuttini FM.(PubMed)
(348) Vitamin D status, bone mineral density, and the development of radiographic osteoarthritis of the knee: The Rotterdam Study by Bergink AP1, Uitterlinden AG, Van Leeuwen JP, Buurman CJ, Hofman A, Verhaar JA, Pols HA.(PubMed)
(349) Vitamin D deficiency is associated with progression of knee osteoarthritis by Zhang FF1, Driban JB2, Lo GH3, Price LL4, Booth S5, Eaton CB6, Lu B7, Nevitt M8, Jackson B9, Garganta C10, Hochberg MC11, Kwoh K12, McAlindon TE2.(PubMed)
(350) Low levels of vitamin D and worsening of knee osteoarthritis: results of two longitudinal studies by Felson DT1, Niu J, Clancy M, Aliabadi P, Sack B, Guermazi A, Hunter DJ, Amin S, Rogers G, Booth SL.(PubMed)
(351) Serum levels of vitamin D, sunlight exposure, and knee cartilage loss in older adults: the Tasmanian older adult cohort study by Ding C1, Cicuttini F, Parameswaran V, Burgess J, Quinn S, Jones G.(PubMed)
(352) Comparative effectiveness of B and e vitamins with diclofenac in reducing pain due to osteoarthritis of the knee by Dehghan M1.(PubMed)
(353) B-vitamin mixture improves the analgesic effect of diclofenac in patients with osteoarthritis: a double blind study by Magaña-Villa MC1, Rocha-González HI, Fernández del Valle-Laisequilla C, Granados-Soto V, Rodríguez-Silverio J, Flores-Murrieta FJ, Carrasco-Portugal MC,Reyes-García JG.(PubMed)
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