Monday, April 18, 2016

The Best Smoothie of Alfalfa Sprouts Juice and Green Tea for Prevention and Treatment of Cervical Polyps

Kyle J. Norton(Scholar, Master of Nutrient, all right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.


The smoothie for reduced risk and treatment of cervical polyps
Yield: 2 servings (about 8 ounces each)
3/4 cup alfalfa sprouts juice
1/4 cup honey for taste
1 cup green tea drink (Make from 4 grams of green tea, a slice of ginger and a cup of hot water lipped for 5 minutes, and let cool to room temperature)

1. Place all ingredients in a blender and puree about 1 minute
2. Blend on high speed about 1 minute or until the mixture is thick and the ice is well crushed. Add more green tea drink if needed
3. Serve immediately

The finding of a natural source for reduced risk and treatment of  cervical polyps to replace the conventional medicine has been running into many obstacles, many ingredients showed initially with promising result in animal studies have not produced same potentials in either large sample size and mutli centers human trials.

Cervical polyps are small, elongated tumors that grow on the cervix caused by hormone imblalnce and chronic inflammation of cervix. According to the statistic, the prevalence of any abnormality within a cervical polyp is significantly lower in postmenopausal, compared with premenopausal women(1).
Phytoestrogen, such as  isoflavonoids found in legume exhibited estrogenic and anti estorgenic effects depending to the levels of estrogen in women  may inhibit the induction of cervical polyps caused by hormone imbalance(2).
In menopausal women, estrogen deficiency after menopause not only accelerated the redox imbalance and insulin signaling but also induced oxidative stress (OS) and insulin resistance (IR), intake of isoflavones from varies sources including may exhibited estrogen balancing effect in ameliorated risk of oxidative stress (OS) and insulin resistance (IR)(3).
Dr. Kurzer MS and Dr. Xu X. Said, " phytoestrogens include isoflavones.......... A number of these compounds have been identified in fruits, vegetables, and whole grains commonly consumed by humans.....(such as) alfalfa sprouts,,..(through) proposed mechanisms include estrogenic and antiestrogenic effects"(4).

Green tea has been a precious drink in traditional Chinese culture and used exceptional in socialization for more than 4000 thousand years. Due to its commercial values and health effects, green tea now has been cultivated all over the world in suitable climate. Its phytochemicals such as polyphenols (GTP) have shown to inhibit over expression of chronic inflammation of pro inflammatory cytokine TNF-α.(5) in chronic inflammatory diseases(6).
In animal model, alcoholic extracts of green tea (AE) displayed anti-inflammatory and analgesic effects against chronic inflammatory disorders, the UNIFOR, Fortaleza, insisted(7).

The effectiveness of  Alfalfa Sprouts Juice and Green Tea may serve as cornerstones of pharmaceutical target for further studies in production of a potential medication for for Reduced Risk of Consequences of  Cervical Polyps with little or no adverse effects.

Women who are pregnancy may want to stop drinking excessively. Otherwise, intake of
Smoothie of  Alfalfa Sprouts Juice and Green Tea may Reduced Risk and treatment of  Cervical Polyps.
Life style and dietary patter change are recommended.


All Forms of Arthritis are Curable
You Can Eliminate Osteoarthritis
By addressing the Underlying Causes through Clinical Trials and Studies


Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months


Super foods Library, Eat Yourself Healthy With The Best of the Best Nature Has to Offer

References
(1) Cervical polyps in postmenopausal women: is there a difference in risk? by Schnatz PF1, Ricci S, O'Sullivan DM.(PubMed)
(2) Phytoestrogen content and estrogenic effect of legume fodder by Saloniemi H1, Wähälä K, Nykänen-Kurki P, Kallela K, Saastamoinen I.(PubMed)
(3) Amelioration of oxidative stress and insulin resistance by soy isoflavones (from Glycine max) in ovariectomized Wistar rats fed with high fat diet: the molecular mechanisms by Sankar P1, Zachariah B2, Vickneshwaran V3, Jacob SE4, Sridhar MG3(PubMed)
(4) Dietary phytoestrogens by Kurzer MS1, Xu X.(PubMed)
(5) Protective actions of green tea polyphenols and alfacalcidol on bone microstructure in female rats with chronicinflammation by Shen CL1, Yeh JK, Samathanam C, Cao JJ, Stoecker BJ, Dagda RY, Chyu MC, Wang JS.(PubMed)
(6) Green tea polyphenols attenuate deterioration of bone microarchitecture in female rats with systemic chronic inflammation by Shen CL1, Yeh JK, Samathanam C, Cao JJ, Stoecker BJ, Dagda RY, Chyu MC, Dunn DM, Wang JS.(PubMed)
(7) Evaluation of the anti-inflammatory and analgesic effects of green tea (Camellia sinensis) in mice. by Mota MA1, Landim JS1, Targino TS1, Silva SF1, Silva SL1, Pereira MR1.(PubMed)

Most Common Diseases of 50plus: Pulmonary vascular disease(Respiratory disease): Pulmonary edema- The Causes

Kyle J. Norton(Scholar and Master of Nutrients, all right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

                           Respiratory Disease

Respiratory Disease is defined as medical conditions, affecting the breathing organ and tissues including Inflammatory lung disease, Obstructive lung diseases, Restrictive lung diseases, Respiratory tract infections, trachea, bronchi, bronchioles, alveoli, the nerves and muscles breathing, etc,.

     Pulmonary vascular disease:  Pulmonary embolism

Pulmonary vascular disease is defined as a condition of blood flow to the lung’s artery is blocked suddenly due to a blood clot somewhere in the body, including pulmonary embolism, chronic thromboembolic disease, pulmonary arterial hypertension, pulmonary veno-occlusive disease, pulmonary arteriovenous malformations, pulmonary edema, etc.
                                                   
Pulmonary embolism (PE) is defined as a condition of blockage of blood flow due to a blood clot of either in main artery of the lung or somewhere else in the body. In most cases, it is in the deep veins of the legs or pelvic. The disease is a common and affect as many as 500,000 persons annually in the United States
                                            The Causes
1. Popliteal venous aneurysm
There is a report of a case of surgical treatment of a 44 years old man, for a popliteal venous aneurysm that was complicated by pulmonary thromboembolism(6).
2. Total hip/knee arthroplasty
Total hip/knee arthroplasty Total hip/knee arthroplasty may cause venous thromboembolism (VTE) as a postoperative complication. There is a report of a patient who developed pulmonary embolism (PE) 6 days after arthroscopic rotator cuff repair but recovered without sequelae. In this case, the possibility of DVT of the lower limbs was denied by contrast-enhanced CT. Most possibly, the source of PE was deep vein thrombosis (DVT) of the upper limb under Desault fixation which showed arthroscopic surgery-related swelling postoperatively(7).
3. Vertebral compression fractures (VCFs)
i n osteoporotic VCFs, pulmonary cement embolism was detected in 23% of PVP sessions, developed in the distal to third-order pulmonary arteries, and was related to leakage into the inferior vena cava, according to the study by Seoul National University Bundang Hospital(8).
4. Medication
Medication such as Heparin , bivalirudin (0.1 mg/kg bolus and 1.75 mg/kg per h infusion) plus warfarin in certain patient can be a potential cause of pulmonary embolism.
A 68-year-old man was referred to the emergency department 6 h after onset of sudden acute dyspnoea. Immediate ECG showed sinus tachycardia with the typical S1-Q3-T3 pattern and incomplete right bundle branch block. The echocardiogram showed the presence of mobile thrombus in the right atrium, a distended right ventricle with free wall hypokinesia and displacement of the interventricular septum towards the left ventricle. Lung spiral computed tomography (CT) showed bilateral pulmonary involvement and confirmed the picture of a thrombotic system in the right atrium and caval vein. Thrombolytic treatment with recombinant tissue plasminogen activator (rt-PA) and heparin (alteplase 10 mg bolus, then 90 mg over 2 h) was administered. Six hours after thrombolysis bleeding gums and significant reduction in platelet count (around 50,000) were observed(9).
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Sources
(6) http://www.ncbi.nlm.nih.gov/pubmed/23423692
(7) http://www.ncbi.nlm.nih.gov/pubmed/23533883
(8) http://www.ncbi.nlm.nih.gov/pubmed/19332856
(9) http://www.ncbi.nlm.nih.gov/pubmed/21031046

Sunday, April 17, 2016

Most Common Disease of50plus: The Clinical trials and Studies of Musculo-Skeletal disorders(MSDs) - Osteoarthritis: Treatment In herbal and traditional Chinese medicine - The alternative natural treatment

Kyle J. Norton (Scholar)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

Musculoskeletal disorders (MSDs) are medical condition mostly caused by work related occupations and working environment, affecting patients’ muscles, joints, tendons, ligaments and nerves and developing over time. A community sample of 73 females and 32 males aged 85 and over underwent a standardised examination at home. Musculoskeletal pain was reported by 57% of those interviewed. A major restriction of joint movement range was frequent in the shoulder but uncommon in other joints(1).

Types of Musculo-Skeletal disorders in elder(2)

1. Osteoarthritis
2. Gout
3. Rheumatoid Arthritis
4. Polymalagia Arthritis
5. Cervical myleopathy and spinal canal stenosis
6. Osteoporosis
7. Low back pain
8. Fibromyalgia



                                                      Osteoarthritis


Osteoarthritis (OA), a form of arthritis, is defined as a condition of as a result of aging causes of wear and tear on a joint, affecting over 25 million people in the United States in alone. University of Porto Medical School indicated that one must understand the differences in prevalence and incidence estimates of osteoarthritis (OA), according to case definition, in knee, hip and hand joints(3).
The characteristics of osteoarthritis are aching pain(5), stiffness(6), or difficulty of moving the joint or joints(7). The pain usually gets worse in change of weather, at night and in the advanced diseases, the pain can occur even at rest(8). Today management of osteoarthritis (OA) focuses on pain relief and improved physical function through pharmacological, non pharmacological, and surgical treatments(4).

                           The Treatment

B. In herbal and traditional Chinese medicine perspective
B.7. The alternative natural treatment
Beside suggesting certain herbal medicine for treatment of osteoarthritis, modern herbal and TCM medicine doctors may also combine other natural treatment for alleviating symptoms of the disease1. Use Ice or Heat Therapies therapy
Ice therapy such as repeated, rather than continuous, ice applications may be considered as an effective treatment for some patient with osteoarthritis(380) as it reduces swelling and pain(380), if the therapy is applied correctly to avoid side effects, and prevent possible further injury, but according to Dr. Mac Auley DC. as the therapy has shown to impair reflex activity and motor function up to 30 following treatment.(378). The doctor also said that guidance on the duration, frequency, or length of ice treatment may be depending on the particular ice therapy, injury location, or severity(379). Heat therapy has shown to loosen tissues and relax stiff joints may also benefits to some patient of osteoartritis(381). According to the study by University of Haifa, thermal and athermal short-wave diathermyhave shown effectively for the management of knee osteoarthritis(382).

2. Acupuncture
The most oldest form of medical treatment in traditional Chinese medicine has been known for its function in relief pain(383) and functional limitation(384) for chronic patient, including patient with moderate or severe chronic knee pain(383), peripheral joint osteoarthritis(384) and hip osteoarthritis(385) with many different techniques, such as acupuncture techniques, moxibustion, transcutaneous electrical nerve stimulation(392).
In pain management, acupuncture is found to significant reduce pain intensity, improve functional mobility and quality of life in patient with osteoarthritis (386). According to the University of York, in patient with knee osteoarthritis, in a systematic review with network meta-analysis, indicated that
acupuncture is considered as one of the more effective physical treatments for alleviating osteoarthritis knee pain in the short-term, but due to poor quality of the study(387), larger sample size and multi sample studies are necessary to confirm this claim.
Dr. Vas J. and Dr..White A said "... optimal results from acupuncture treatment for osteoarthritis of the knee may involve: climatic factors, particularly high temperature; high expectations of patients; minimum of four needles; electroacupuncture rather than manual acupuncture, and particularly, strong electrical stimulation to needles placed in muscle; and a course of at least 10 treatments"(388)


3. Massage Therapy
Massage therapy has been used in traditional Chinese medicine over thousands of year for treatment of osteoarthritis (OA)(392)(389), especially for OA patient for short-term pain relief(389). In a sixty-eight adults with radiographically confirmed OA, massage therapy seems to be most efficacious relief pain, stiffness, and improve physical function limitation for patient OA of the knee(390).
According to the joint study by the University Medical Center and Avans University of Applied Scienc, in a systematic review of randomised clinical trials, said that there is a evidence indicated that massage improves function in the short term compared to no treatment in people with knee arthritis(391)


4. Spa therapy
Spa therapy may be one the effective technique for treatment of lower back pain, according to some studies(392)(393)9394). In patient with rheumatoid arthritis, spa therapy showed to relief symptoms of pain, stiffness and mobility(395). According to the joint study by the University of Siena and Spa Centre of Fonteverde Natural Spa Resort, the clinical trials conducted exhibited the support of spa therapy on pain, function and quality of life in hand OA(396), if used conjunction with the application of thermal treatments(396). In patient with knee osteoarthritis, especially in European countries, although the spa treatment is still the subject of debate, the existence of data of some clinical trials suggested a beneficial effect of spa therapy on pain, function and quality of life in knee OA if the treatment cover the duration from six to nine months(397).
In the study conducted by the University of Siena, Viale Bracci, spa therapy showed effectively in modified plasma levels of leptin and adiponectin of which are, important mediators of cartilage metabolism and related to the development of knee osteoarthritis(398)

5. Hydrotherapy
Hydrotherapy, using water for the treatment of disease has shown some beneficiary for treating pain in patient with lower back pain(399), joint hemorrhages(400) and multiple sclerosis(401). In patient with knee osteoarthritis, water therapy reduced knee pain and increased knee function in participants with knee OA as effectively as conventional based therapy(402).In a randomized controlled trial conducted among 152 older persons with chronic symptomatic hip or knee OA by the University of Sydney, hydrotherapy or Tai Chi classes showed to enhance large and sustained improvements in physical function for many older, sedentary individuals with chronic hip or knee OA(403).
In lower limb osteoarthritis, the study of 106 patients (93 women, 13 men) over the age of 60 years with confirmed hip and/or knee OA suggested that water exercise induced significantly reduction in pain and improvement in physical function of the participants after 1 year with a favourable cost--benefit outcome(404).
Unfortunately, the water gym study conducted by the Universidade Estadual Paulista Júlio Mesquita Filho, showed no beneficiary in improving symptoms of individuals with knee OA(405).


6. Tai Chi
Tai chi, an ancient form of mind-body exercise or technique used in Chinese with meditative movements that promote balance and healing of the mind and body induced mental concentration, physical balance, muscle relaxation, and relaxed breathing(406).
In chronic diseases, such as osteoarthritis, Tai Chi improve physical performance(408), such as walking distance (6MWD) and knee extensor strength and pain(408) and stiffness of patient with osteoarthritis(407) and knee osteoarthritis(408)(409).
In the assessing the effectiveness of Tai Chi for knee osteoarthritis, conducted by Tufts University School of Medicine, Tai Chi therapy improved WOMAC pain(411) and stiffness scores, physical(411) and lower-extremity function, knee proprioception, ect., after 12, 24 and 48 weeks(410).


7. Yoga
An ancient form of medical technique originated from India, is become a popular multimodal mind-body exercise in the Western world for promoted flexibility, strength, endurance, and balance(412). According to the study by the University of Minnesota, Minneapolis (CC, JFW), Yoga 45 to 90 mins per session for 6 to 12 wks, reduced pain, stiffness, and swelling, inpatient with osteoarthritis of the knees(413) or osteoarthritis but the study showed an inconclusive outcome on physical function and psychosocial well-being(412).

8. Chiropractic
Chiropractic is one the alternative therapy for diagnosis and treatment of Musculoskeletal disorders (MSDs), including osteoarthritis. It is one the primary care of hip osteoarthritis in Denmark(425)
According to the Cleveland Chiropractic College, chiropractic increased range of motion, improved balance and gait speed, and decreased disability after a 12-week course in a 70 year old geriatric patient with left hip pain, a history of repetitive falls, poor balance, myofascial dysfunction, and hip osteoarthritis(424) of that may contribute to a conservative management options for patient with hip osteoarthritis(426).
Chiropractic management showed to decreased WOMAC scores and increases in hip range of motion in patient of hip osteoarthritis, according to the study by Autralia(427) and may provide a short-term benefit to relieve hip pain for patients with hip osteoarthritis waiting for hip surgery(428), according to the report of Scandinavian College of Chiropractic.
Used in conjunction with heat, chiropractic spinal manipulation,showed more effective for the treatment of low back pain in patient of osteoarthritis (OA) in comparison of the application of moist heat or chiropractic spinal manipulation alone(429).

9. Chinese Herbal Bath Therapy
Chinese herbal bath therapy (CHBT) has been used traditionally for its effects on analgesics and anti-inflammation against pain, especially for patient with knee osteoarthritis(495). According to the joint study by reviewed of a total of 529 abstracts identified from 7 English
and Chinese databases conducted by the Shuguang Hospital affiliated to Shanghai University of Traditional Chinese Medicine, Tufts University and Tufts University School of Medicine, the therapy effectively reduced pain, improved physical performance, and wellness in comparison to standard western treatment with little or no adverse effects(496).


Arthritis Is Curable
You Can Eliminate Osteoarthritis
By addressing the Underlying Causes through Clinical Trials and Studies

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Super foods Library, Eat Yourself Healthy With The Best of the Best Nature Has to Offer recommended by Kyle J. Norton

Back to Kyle J. Norton Home page http://kylejnorton.blogspot.ca


References
(1) Prevalence of rheumatic symptoms, rheumatoid arthritis, ankylosing spondylitis, and gout in Shanghai, China: a COPCORD study by Dai SM1, Han XH, Zhao DB, Shi YQ, Liu Y, Meng JM.(PubMed)
(2) Musculoskeletal Disorders in the Elderly by Ramon Gheno, Juan M. Cepparo, Cristina E. Rosca,1 and Anne Cotten(PMC)
(3) The effect of osteoarthritis definition on prevalence and incidence estimates: a systematic review by Pereira D1, Peleteiro B, Araújo J, Branco J, Santos RA, Ramos E.(PubMed)
(4) Effect of therapeutic aquatic exercise on symptoms and function associated with lower limb osteoarthritis: systematic review with meta-analysis by Waller B1, Ogonowska-Slodownik A2, Vitor M3, Lambeck J4, Daly D5, Kujala UM6, Heinonen A7.(PubMed)
(5) Effects of therapeutic ultrasound on pain, physical functions and safety outcomes in patients with kneeosteoarthritis: A systematic review and meta-analysis by Zhang C1, Xie Y2, Luo X3, Ji Q3, Lu C3, He C4, Wang P3.(PubMed)
(6) Oral intake of purple passion fruit peel extract reduces pain and stiffness and improves physical function in adult patients with knee osteoarthritis by Farid R1, Rezaieyazdi Z, Mirfeizi Z, Hatef MR, Mirheidari M, Mansouri H, Esmaelli H, Bentley G, Lu Y, Foo Y, Watson RR.(PubMed)
(7) Functional ability, mobility, and pain before and after knee replacement in patients aged 75 and older: a cross-sectional study by Limnell K1, Jämsen E, Huhtala H, Jäntti P, Puolakka T, Jylhä M.(PubMed)
(8) The symptoms of OA and the genesis of pain by David J. Hunter, MBBS PhD,1,2 Jason J. McDougall, BSc PhD,3 and Francis J. Keefe4(PubMed)
(376) Management of Osteoarthritis with Avocado/Soybean Unsaponifiables by Christiansen BA1, Bhatti S2, Goudarzi R3, Emami S4.(PubMed)
(377) Avocado/soybean unsaponifiables prevent the inhibitory effect of osteoarthritic subchondral osteoblasts on aggrecan and type II collagen synthesis by chondrocytes by Henrotin YE1, Deberg MA, Crielaard JM, Piccardi N, Msika P, Sanchez C.(PubMed)
(378) Ice therapy: how good is the evidence? by Mac Auley DC1.(PubMed)
(379) Do textbooks agree on their advice on ice? by MacAuley D1.(PubMed)
(380) Should I use heat or ice to ease knee pain from osteoarthritis?[No authors listed](PubMed)
(381) Osteoarthritis-dependent changes in antinociceptive action of Nav1.7 and Nav1.8 sodium channel blockers: An in vivo electrophysiological study in the rat by Rahman W1, Dickenson AH2(PubMed)
(382) Effectiveness of thermal and athermal short-wave diathermy for the management of knee osteoarthritis: a systematic review and meta-analysis by Laufer Y1, Dar G.(PubMed)
(383) Acupuncture for chronic knee pain: a randomized clinical trial by Hinman RS1, McCrory P2, Pirotta M3, Relf I3, Forbes A4, Crossley KM5, Williamson E6, Kyriakides M3, Novy K3, Metcalf BR1, Harris A7, Reddy P8, Conaghan PG9, Bennell KL1.(PubMed)
(384) Acupuncture for peripheral joint osteoarthritis by Manheimer E1, Cheng K, Linde K, Lao L, Yoo J, Wieland S, van der Windt DA, Berman BM, Bouter LM.(PubMed)
(385) Effect of physical therapy on pain and function in patients with hip osteoarthritis: a randomized clinical trial by Bennell KL1, Egerton T1, Martin J1, Abbott JH2, Metcalf B1, McManus F1, Sims K3, Pua YH4, Wrigley TV1, Forbes A5, Smith C5, Harris A6, Buchbinder R7.(PubMed)
(386) Pain management with acupuncture in osteoarthritis: a systematic review and meta-analysis. by Manyanga T1, Froese M, Zarychanski R, Abou-Setta A, Friesen C, Tennenhouse M, Shay BL.(PubMed)
(387) Acupuncture and other physical treatments for the relief of pain due to osteoarthritis of the knee: network meta-analysis by Corbett MS1, Rice SJ, Madurasinghe V, Slack R, Fayter DA, Harden M, Sutton AJ, Macpherson H, Woolacott NF.(PubMed)
(388) Evidence from RCTs on optimal acupuncture treatment for knee osteoarthritis--an exploratory review by Vas J1, White A.(PubMed)
(389) Gait analysis of patients with knee osteoarthritis before and after Chinese massage treatment by Qingguang Z, Min F, Li G, Shuyun J, Wuquan S, Jianhua L, Yong L.(PubMed)
(390) Massage therapy for osteoarthritis of the knee: a randomized controlled trial by Perlman AI1, Sabina A, Williams AL, Njike VY, Katz DL.(PubMed)
(391) Massage therapy has short-term benefits for people with common musculoskeletal disorders compared to no treatment: a systematic review by Bervoets DC1, Luijsterburg PA1, Alessie JJ2, Buijs MJ2, Verhagen AP1.(PubMed)
(392) Complementary and alternative medicine in osteoarthritis by De Luigi AJ1.(PubMed)
(393) Spa therapy and balneotherapy for treating low back pain: meta-analysis of randomized trials by Pittler MH1, Karagülle MZ, Karagülle M, Ernst E.(PubMed)
(394) The effect of spa therapy in chronic low back pain: a randomized controlled, single-blind, follow-up study by Tefner IK1, Németh A, Lászlófi A, Kis T, Gyetvai G, Bender T.(PubMed)
(395) Balneotherapy (or spa therapy) for rheumatoid arthritis by Verhagen AP1, Bierma-Zeinstra SM, Boers M, Cardoso JR, Lambeck J, de Bie R, de Vet HC.(PubMed)
(396) May spa therapy be a valid opportunity to treat hand osteoarthritis? A review of clinical trials and mechanisms of action by Fortunati NA1, Fioravanti A2, Seri G1, Cinelli S2, Tenti S3.(PubMed)
(397) Spa therapy: can be a valid option for treating knee osteoarthritis? by Tenti S1, Cheleschi S, Galeazzi M, Fioravanti A.(PubMed)
(398) Effects of spa therapy on serum leptin and adiponectin levels in patients with knee osteoarthritis. by Fioravanti A1, Cantarini L, Bacarelli MR, de Lalla A, Ceccatelli L, Blardi P.(PubMed)
(399) Effectiveness of Back School program versus hydrotherapy in elderly patients with chronic non-specific low back pain: a randomized clinical trial by Costantino C1, Romiti D.(PubMed)
(400) Effects of therapeutic exercise and hydrotherapy on pain severity and knee range of motion in patients with hemophilia: a randomized controlled trial by Mazloum V1, Rahnama N1, Khayambashi K1.(PubMed)
(401) Hydrotherapy for the treatment of pain in people with multiple sclerosis: a randomized controlled trial by Castro-Sánchez AM1, Matarán-Peñarrocha GA, Lara-Palomo I, Saavedra-Hernández M, Arroyo-Morales M, Moreno-Lorenzo C.(PubMed)
(402) Hydrotherapy versus conventional land-based exercise for the management of patients with osteoarthritis of the knee: a randomized clinical trial by Silva LE1, Valim V, Pessanha AP, Oliveira LM, Myamoto S, Jones A, Natour J.(PubMed)
(403) Physical activity for osteoarthritis management: a randomized controlled clinical trial evaluating hydrotherapy or Tai Chi classes by Fransen M1, Nairn L, Winstanley J, Lam P, Edmonds J.(PubMed)
(404) Randomised controlled trial of the cost-effectiveness of water-based therapy for lower limb osteoarthritis by Cochrane T1, Davey RC, Matthes Edwards SM.(PubMed)
(405) Effect of watergym in knee osteoarthritis by Guerreiro JP1, Claro RF1, Rodrigues JD1, Freire BF1.(PubMed)
(406) The effects of tai chi on depression, anxiety, and psychological well-being: a systematic review and meta-analysis by Wang F, Lee EK, Wu T, Benson H, Fricchione G, Wang W, Yeung AS.(PubMed)
(407) The effect of Tai Chi on four chronic conditions-cancer, osteoarthritis, heart failure and chronic obstructive pulmonary disease: a systematic review and meta-analyses by Chen YW1, Hunt MA1, Campbell KL1, Peill K2, Reid WD3.(PubMed)
(408) Patient-Reported Outcomes Measurement Information System (PROMIS) instruments among individuals with symptomatic knee osteoarthritis: a cross-sectional study of floor/ceiling effects and construct validity by Driban JB1, Morgan N2,3, Price LL4, Cook KF5, Wang C6.(PubMed)
(409) Tai Chi is effective in treating knee osteoarthritis: a randomized controlled trial by Wang C1, Schmid CH, Hibberd PL, Kalish R, Roubenoff R, Rones R, McAlindon T.(PubMed)
(410) Tai Chi for treating knee osteoarthritis: designing a long-term follow up randomized controlled trial by Wang C1, Schmid CH, Hibberd PL, Kalish R, Roubenoff R, Rones R, Okparavero A, McAlindon T.(PubMed)
(411) Efficacy of Tai Chi on pain, stiffness and function in patients with osteoarthritis: a meta-analysis by Yan JH1, Gu WJ, Sun J, Zhang WX, Li BW, Pan L.(PubMed)
(412) Effects of Yoga on Symptoms, Physical Function, and Psychosocial Outcomes in Adults with Osteoarthritis: A Focused Review by Cheung C1, Park J, Wyman JF.(PubMed)
(413) Iyengar yoga for treating symptoms of osteoarthritis of the knees: a pilot study by Kolasinski SL1, Garfinkel M, Tsai AG, Matz W, Van Dyke A, Schumacher HR.(PubMed)
(414) Topical Ginger Treatment With a Compress or Patch for Osteoarthritis Symptoms. by Therkleson T1.(PubMed)
(415) Ginger Therapy for Osteoarthritis: A Typical Case by Therkleson T1.(PubMed)
(416) Topical Ginger Treatment With a Compress or Patch for Osteoarthritis Symptoms by Therkleson T1(PubMed)
(417) Zucapsaicin(Wikipedia)
(418) Civamide cream 0.075% in patients with osteoarthritis of the knee: a 12-week randomized controlled clinical trial with a longterm extension by Schnitzer TJ1, Pelletier JP, Haselwood DM, Ellison WT, Ervin JE, Gordon RD, Lisse JR, Archambault WT, Sampson AR, Fezatte HB, Phillips SB, Bernstein JE.(PubMed)
(419) High strength capsaicin cream for osteoarthritis pain: rapid onset of action and improved efficacy with twice daily dosing by Schnitzer TJ1, Posner M, Lawrence ID.(PubMed)
(420) Effectiveness and safety of topical capsaicin cream in the treatment of chronic soft tissue pain.
Chrubasik S1, Weiser T, Beime B.(PubMed)
(421) Neuromuscular electrostimulation techniques: historical aspects and current possibilities in treatment of pain and muscle waisting by Heidland A1, Fazeli G, Klassen A, Sebekova K, Hennemann H, Bahner U, Di Iorio B.(PubMed)

(422) Osteoarthritis: physical medicine and rehabilitation--nonpharmacological management.Stemberger R1, Kerschan-Schindl K.(PubMed)
(423) Transcutaneous electrostimulation for osteoarthritis of the knee by Rutjes AW1, Nüesch E, Sterchi R, Kalichman L, Hendriks E, Osiri M, Brosseau L, Reichenbach S, Jüni P.(PubMed)
(424) Chiropractic care of a 70-year-old female patient with hip osteoarthritis by Strunk RG1, Hanses M.(PubMed)
(425) Prevalence of hip osteoarthritis in chiropractic practice in Denmark: a descriptive cross-sectional and prospective study by Poulsen E1, Christensen HW, Overgaard S, Hartvigsen J.(PubMed)
(426) A randomized controlled trial of chiropractic management of the lower limb kinetic chain for the treatment of hiposteoarthritis: a study protocol by de Luca K1, Pollard H, Brantingham J, Globe G, Cassa T.(PubMed)
(427) Chiropractic management of the kinetic chain for the treatment of hip osteoarthritis: an Australian case series by de Luca K1, Pollard H, Brantingham J, Globe G, Cassa T.(PubMed)
(428) Effects of chiropractic care on pain and function in patients with hip osteoarthritis waiting for arthroplasty: a clinical pilot trial by Thorman P1, Dixner A, Sundberg T.(PubMed)
(429) Efficacy of treating low back pain and dysfunction secondary to osteoarthritis: chiropractic care compared with moist heat alone by Beyerman KL1, Palmerino MB, Zohn LE, Kane GM, Foster KA.(PubMed)
(495) Complementary and Alternative Medicine Use Among Adults and Children: United States, 2007 by Patricia M. Barnes, M.A., and Barbara Bloom, M.P.A., Division of Health Interview Statistics, National Center for Health Statistics; and Richard L. Nahin, Ph.D., M.P.H., National Center for Complementary and Alternative Medicine, National Institutes of Health
(496) Chinese Herbal Bath Therapy for the Treatment of Knee Osteoarthritis: Meta-Analysis of Randomized Controlled Trials by Chen B1, Zhan H1, Chung M2, Lin X1, Zhang M1, Pang J1, Wang C3.(PubMed)

The Smoothie of Orange, Yogurt and Whole Milk for Prevention and Treatment of Bacterial Vaginosis

Kyle J. Norton(Scholar, Master of Nutrients), all right reserved.
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

The Incredible and Effective smoothie for Prevention and treatment of  Bacterial Vaginosis
Yield: 2 servings (about 8 ounces each)
1   cup orange
1/2 cup yogurt
1 cup whole milk
1. Place all ingredients in a blender and puree about 1 minute
2. Blend on high speed about 1 minute or until the mixture is thick and the ice is well crushed.
3. Serve immediately

Bacterial Vaginosis is a condition of abnormal vagina discharge due to over growth of atypical bacteria in the vagina

The finding of a natural source for reduced risk and treatment of  Amenorrhea to replace the conventional medicne has been running into many obstacles, many ingredients showed initially with promising result in animal studies have not produced same potentials in either large sample size and mutli centers human trials. According to the convenience sample of 192 women selected from an online community devoted to the discussion of women's health, interest women expressed favorable alternative treatments of yeast infections and bacterial vaginosis(1).

Absence of vaginal lactobacilli has been associated with symptomatic bacterial vaginosis (BV). According to the University of Washington, Lactobacillus recolonization via yogurt may have a positive effective in prevention and treatment of Bacterial Vaginosis(2).
Vaginal washing, typically with water alone or with soap and water, was associated with an approximately 40% decreased likelihood of Lactobacillus isolation(3).


Vitamin D, found abundantly in whole milk, is a fat-soluble secosteroids found in small amount in few foods, including salmon, mackerel, sardines and tuna. The vitamin plays an important role in modulation of cellular proliferation, apoptosis induction, tumor growth suppression and promotion in absorption of minerals, including calcium, iron, magnesium, phosphate and zinc. According tot he the Ohio State University, the vitamin D may protect against the recurrence of bacterial vaginosis(4), as low serum vitamin D concentration was associated with increased prevalence of bacterial vaginosis (BV) among pregnant women(5).
Dr. Hensel KJ and colleagues in the study of pregnancy-specific association of vitamin D deficiency and bacterial vaginosis said, "Risk factors for BV differ by pregnancy status. VDD was a modifiable risk factor for BV among pregnant women; evaluation of vitamin D supplementation for prevention or adjunct therapy of BV in pregnancy is warranted"(6).

Vitamin C found abundantly in orange, a water soluble vitamin,  best known for its function in free radical scavengers activity and regenerating oxidized vitamin E for immune support may be a potential ingredient for treatment of bacterial vaginosis, according to the Texas Christian University(7).
In a randomised, double-blind, placebo-controlled, parallel-group clinical trial. One hundred and forty-two women, chronic use of of 250 mg ascorbic acid vaginal tablets on 6 days per month for 6 months after successful treatment of bacterial vaginosis halves the risk of recurrence from 32.4% to 16.2%(8).
The effectiveness of Orange, Yogurt and Whole Milk may serve as cornerstones of pharmaceutical target for further studies in production of a potential medication for for Reduced Risk and treatment of  Bacterial Vaginosis with little or no adverse effects.

Women who are at increased risk of  Bacterial Vaginosis may drink at least one serving daily and women with  Bacterial Vaginosis  may drink as much as they can, depending to the digestive toleration.
Life style and dietary patter change are recommended.


All Forms of Arthritis are Curable
You Can Eliminate Osteoarthritis
By addressing the Underlying Causes through Clinical Trials and Studies


Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months


Super foods Library, Eat Yourself Healthy With The Best of the Best Nature Has to Offer


References
(1) Alternative therapies for bacterial vaginosis: a literature review and acceptability survey by Boskey ER1.(PubMed)
(2) Common complementary and alternative therapies for yeast vaginitis and bacterial vaginosis: a systematic review by Van Kessel K1, Assefi N, Marrazzo J, Eckert L.(PubMed)
(3) In Vitro Susceptibilities of Lactobacilli and Organisms Associated with Bacterial Vaginosis to Melaleuca alternifolia (Tea Tree) Oi by K. A. Hammer, C. F. Carson(PMC)
(4) A blinded, randomized controlled trial of high-dose vitamin D supplementation to reduce recurrence of bacterial vaginosis by Turner AN1, Carr Reese P2, Fields KS3, Anderson J3, Ervin M3, Davis JA2, Fichorova RN4, Roberts MW3, Klebanoff MA5, Jackson RD6.(PubMed)
(5) Bacterial vaginosis and season, a proxy for vitamin D status by Klebanoff MA1, Turner AN.(PubMed)
(6) Pregnancy-specific association of vitamin D deficiency and bacterial vaginosis by Hensel KJ1, Randis TM, Gelber SE, Ratner AJ.(PubMed)
(7) The effectiveness of intravaginal vitamin C versus placebo for the treatment of bacterial vaginosis: a systematic review protocol by Welch C1, Baker K1.(PubMed)
(8) Efficacy of vitamin C vaginal tablets as prophylaxis for recurrent bacterial vaginosis: a randomised, double-blind, placebo-controlled clinical trial by Krasnopolsky VN1, Prilepskaya VN, Polatti F, Zarochentseva NV, Bayramova GR, Caserini M, Palmieri R.(PubMed)

Most Common Diseases of 50plus: Pulmonary vascular disease(Respiratory disease): Pulmonary embolism- The Symptoms

Kyle J. Norton(Scholar and Master of Nutrients, all right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

                           Respiratory Disease

Respiratory Disease is defined as medical conditions, affecting the breathing organ and tissues including Inflammatory lung disease, Obstructive lung diseases, Restrictive lung diseases, Respiratory tract infections, trachea, bronchi, bronchioles, alveoli, the nerves and muscles breathing, etc,.

         Pulmonary vascular disease:  Pulmonary embolism


Pulmonary vascular disease is defined as a condition of blood flow to the lung’s artery is blocked suddenly due to a blood clot somewhere in the body, including pulmonary embolism, chronic thromboembolic disease, pulmonary arterial hypertension, pulmonary veno-occlusive disease, pulmonary arteriovenous malformations, pulmonary edema, etc.
                                                   
Pulmonary embolism (PE) is defined as a condition of blockage of blood flow due to a blood clot of either in main artery of the lung or somewhere else in the body. In most cases, it is in the deep veins of the legs or pelvic. The disease is a common and affect as many as 500,000 persons annually in the United States.

                      The Symptoms

1. Dyspnoea and pleuritic chest pain
According to the study by Karolinska Institutet, Department of Clinical Science and Education, Initial symptoms in pulmonary embolism, dominated by dyspnoea and/or pleuritic chest pain were significantly different from those in community-acquired pneumonia, dominated by fever, chills and/or cough (P<0.001)(1).
2. Cough or hemoptysis
Pulmonary embolism (PE) is a life-threatening condition that may present as dyspnea, chest pain, cough or hemoptysis, but often occurs without symptom, according to the study by the New York Medical College(2).
3. Hiccups
There is a report of 3 cases of pulmonary embolism presenting as persistent hiccups.
Including a 52-year-old African-American male without significant prior medical or surgical history presented to the emergency department (ED) with a 3-day history of hiccups. Chest radiograph demonstrating a prominent central pulmonary artery (early Fleishner’s Sign, red arrows) and a cut-off of the pulmonary arteries bilaterally. Computed tomography (CT) showing a saddle embolus (black arrow). B. CT showing a large left pulmonary artery embolus (filling defect, red arrow). C. CT showing a left pulmonary artery embolu(3).
4. Other symptoms
Sudden onset dyspnea was the most frequent symptom in both samples (81 and 78%), followed by chest pain (56 and 39%), fainting or syncope (26 and 22%), and hemoptysis (7 and 5%). At least one of the above symptoms was reported by 756 (94%) of 800 patients. Isolated symptoms and signs of deep vein thrombosis occurred in 3% of the cases. Only 7 (1%) of 800 patients had no symptoms before PE was diagnosed, according to the study by the Università degli Studi di Firenze(4).
5. In severe cases, symptoms include persistent hypotension, arterial oxygen desaturation of less than 70%, myocardial ischemia, Acidosis and hypercarbia accompanied death
Experimental massive pulmonary embolism was created in dogs by injecting a standard-sized clot. Certain changes were found to precede death: 1) persistent hypotension, with fall in arterial blood pressure to levels lower than one half base line, 2) arterial oxygen desaturation of less than 70%, and 3) electrocardiographic changes suggestive of myocardial ischemia. Acidosis and hypercarbia accompanied death(5).

Sources
(1) http://www.ncbi.nlm.nih.gov/pubmed/16816587
(2) http://www.ncbi.nlm.nih.gov/pubmed/23359617
(3) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3555588/
(4) http://www.ncbi.nlm.nih.gov/pubmed/22383978
(5) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1617449/pdf/annsurg01475-0052.pdf

Most Common Disease of50plus: The Clinical trials and Studies of Musculo-Skeletal disorders(MSDs) - Osteoarthritis: Treatment In herbal and traditional Chinese medicine - The Electrostimulation

Kyle J. Norton (Scholar)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

Musculoskeletal disorders (MSDs) are medical condition mostly caused by work related occupations and working environment, affecting patients’ muscles, joints, tendons, ligaments and nerves and developing over time. A community sample of 73 females and 32 males aged 85 and over underwent a standardised examination at home. Musculoskeletal pain was reported by 57% of those interviewed. A major restriction of joint movement range was frequent in the shoulder but uncommon in other joints(1).

Types of Musculo-Skeletal disorders in elder(2)

1. Osteoarthritis
2. Gout
3. Rheumatoid Arthritis
4. Polymalagia Arthritis
5. Cervical myleopathy and spinal canal stenosis
6. Osteoporosis
7. Low back pain
8. Fibromyalgia



                                                      Osteoarthritis


Osteoarthritis (OA), a form of arthritis, is defined as a condition of as a result of aging causes of wear and tear on a joint, affecting over 25 million people in the United States in alone. University of Porto Medical School indicated that one must understand the differences in prevalence and incidence estimates of osteoarthritis (OA), according to case definition, in knee, hip and hand joints(3).
The characteristics of osteoarthritis are aching pain(5), stiffness(6), or difficulty of moving the joint or joints(7). The pain usually gets worse in change of weather, at night and in the advanced diseases, the pain can occur even at rest(8). Today management of osteoarthritis (OA) focuses on pain relief and improved physical function through pharmacological, non pharmacological, and surgical treatments(4).

                           The Treatment

B. In herbal and traditional Chinese medicine perspective
B.6. Electrostimulation
Use of electricity for treatment of pain, muscle dysfunction and sarcopenia can be dated back to Ancient Egyptians and later the Greeks and Romans(421). According to the Abteilung für Physikalische Medizin und Rehabilitation, transcutaneous electrostimulation may be effectively and positively in influence of pain and function, mobility, and quality of life in patients suffering from OA(422). Unfortunately, in the review of 14 trials resulting in the inclusion of 18 small trials in 813 patients, found that electrosimulation does not offer pain relief for effective for pain relief. for patient with osteoarthritis of the knee with the relative droping out rate as high as 95%(423).


Arthritis Is Curable
You Can Eliminate Osteoarthritis
By addressing the Underlying Causes through Clinical Trials and Studies


Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Super foods Library, Eat Yourself Healthy With The Best of the Best Nature Has to Offer recommended by Kyle J. Norton

Back to Kyle J. Norton Home page http://kylejnorton.blogspot.ca

References
(1) Prevalence of rheumatic symptoms, rheumatoid arthritis, ankylosing spondylitis, and gout in Shanghai, China: a COPCORD study by Dai SM1, Han XH, Zhao DB, Shi YQ, Liu Y, Meng JM.(PubMed)
(2) Musculoskeletal Disorders in the Elderly by Ramon Gheno, Juan M. Cepparo, Cristina E. Rosca,1 and Anne Cotten(PMC)
(3) The effect of osteoarthritis definition on prevalence and incidence estimates: a systematic review by Pereira D1, Peleteiro B, Araújo J, Branco J, Santos RA, Ramos E.(PubMed)
(4) Effect of therapeutic aquatic exercise on symptoms and function associated with lower limb osteoarthritis: systematic review with meta-analysis by Waller B1, Ogonowska-Slodownik A2, Vitor M3, Lambeck J4, Daly D5, Kujala UM6, Heinonen A7.(PubMed)
(5) Effects of therapeutic ultrasound on pain, physical functions and safety outcomes in patients with kneeosteoarthritis: A systematic review and meta-analysis by Zhang C1, Xie Y2, Luo X3, Ji Q3, Lu C3, He C4, Wang P3.(PubMed)
(6) Oral intake of purple passion fruit peel extract reduces pain and stiffness and improves physical function in adult patients with knee osteoarthritis by Farid R1, Rezaieyazdi Z, Mirfeizi Z, Hatef MR, Mirheidari M, Mansouri H, Esmaelli H, Bentley G, Lu Y, Foo Y, Watson RR.(PubMed)
(7) Functional ability, mobility, and pain before and after knee replacement in patients aged 75 and older: a cross-sectional study by Limnell K1, Jämsen E, Huhtala H, Jäntti P, Puolakka T, Jylhä M.(PubMed)
(8) The symptoms of OA and the genesis of pain by David J. Hunter, MBBS PhD,1,2 Jason J. McDougall, BSc PhD,3 and Francis J. Keefe4(PubMed)
(421) Neuromuscular electrostimulation techniques: historical aspects and current possibilities in treatment of pain and muscle waisting by Heidland A1, Fazeli G, Klassen A, Sebekova K, Hennemann H, Bahner U, Di Iorio B.(PubMed)

(422) Osteoarthritis: physical medicine and rehabilitation--nonpharmacological management.Stemberger R1, Kerschan-Schindl K.(PubMed)
(423) Transcutaneous electrostimulation for osteoarthritis of the knee by Rutjes AW1, Nüesch E, Sterchi R, Kalichman L, Hendriks E, Osiri M, Brosseau L, Reichenbach S, Jüni P.(PubMed)

The Delicious Smoothie of Green Tea, Aloe Vera juice and Grape for Prevention and Treatment of Pyoderma gangrenosum

Kyle J. Norton(Scholar, Master of Nutrients), all right reserved.
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

The smoothie for prevention and treatment of Pyoderma gangrenosum
Yield: 2 servings (about 8 ounces each)
1 cup grape
1 1/2 cups grape
1/2 cup Aloe Vera juice
1/2 cup green tea drink (Make from 2 grams of green tea and a cup of hot water lipped for 5 minutes, and let cool to room temperature)

1. Place all ingredients in a blender and puree about 1 minute
2. Blend on high speed about 1 minute or until the mixture is thick and the ice is well crushed.
3. Serve immediately

The finding of a natural source for treatment of  pyoderma gangrenosum has been running into many obstacles, many ingredients showed initially with promising result in animal studies have not produced same potentials in large sample size and mutli centers human trials.

Pyoderma gangrenosum, a rare inflammatory skin disorder causes death of the skin tissues induced the development of large, painful sores (ulcers) to your skin, most often on your legs.
According to the University of Louisville, licorice, green tea, pomegranate, turmeric may be sued for treatment of pyoderma gangrenosum, due to its powerful anti inflammatory effect(1).
Dr. Wu J said, "active ingredients, anti-inflammatory properties, clinical effects, and therapeutic potential(rosacea, atopic dermatitis, sensitive and irritated skin, drug-induced skin eruptions, and psoriasis) of colloidal oatmeal, feverfew, licorice, aloe vera, chamomile, and turmeric"(2).

Recent studies by some renowned institutions suggested that green tea(3), Aloe Vera juice(7) and grape(5) may be the next generation of ingredient extracted from natural sources for reduced risk and treatment of pyoderma gangrenosum.

Green tea has been a precious drink in traditional Chinese culture and used exceptional in socialization for more than 4000 thousand years. Due to its commercial values and health effects, green tea now has been cultivated all over the world in suitable climate. 
Green tea epigallocatechin gallate (EGCG), a flavonoid belongings to catechins exhibited potent antioxidant and anti-inflammatory diseases, including Pyoderma gangrenosum(1), according to the joint study lead by Federal University of Mato Grosso (UFMT).

Pu-erh tea, made from the leaves of Camellia sinensis, also possessed activities beneficial for human health, including anti-inflammatory, anti-oxidant, and anti-obesity properties, suggested by Dr. Cai X and colleagues(4).

Resveratrol, a phytochemical in the class of Stilbenoids, found abundantly in blueberry and grape also exhibited anti inflammatory effect against pro inflammatory cytokines(5). According to the investigated the effect of resveratrol on skin lesion, in an atopic dermatitis (AD) mouse model, showed that the phytochemical inhibited the prto inflammatory pathways against skin diseases through modulating the HMGB1 protein expression, a cytokine mediator of inflammation(6).

Aloe Vera is species of succulent plant in the genus Aloe, belonging to the Family Xanthorrhoeaceae, native to Sudan. It has become very popular for commercial cultivation due to its health benefits. According to the University of Pretoria, the herb has been used in treatment of skin disorders, through ts moisturizing and anti-inflammatory effects in modulating the IgE levels of mouse model of atopic dermatitis (AD)(7).
Dr. Benson KF and colleagues in the Aloe vera-based extract of Nerium oleander leaves against skin diseases, said, "NAE-8(®), a novel component of a commercial cosmetic product, showed beneficial antioxidant protection in several cellular models, without the induction of leukocyte activation and secretion of inflammatory cytokines"(8).

Taking altogether, The combination of Green Tea, Aloe Vera juice and Grape may offer the potential effect not only in prevention of the onset and treatment of Pyoderma gangrenosum
 People who are at increased risk of Pyoderma gangrenosum are wise to drink at least one serving daily. People with  Pyoderma gangrenosum, should drink the juice as much as they can, depending to the toleration of digestive system.

Made From Fresh Fruits And Vegetable Recipes
Secret To A Vibrant And Healthy Lifestyle
That You Can Find Easily At The Comfort Of Your Kitchen.


References
(1) Innovations in natural ingredients and their use in skin care by Fowler JF Jr1, Woolery-Lloyd H, Waldorf H, Saini R.(PubMed)
(2) Anti-inflammatory ingredients by Wu J1.(PubMed)
(3) Epigallocatechin gallate and mitochondria-A story of life and death by Oliveira MR1, Nabavi SF2, Daglia M3, Rastrelli L4, Nabavi SM2.(PubMed)
(4) Pu-erh tea extract ameliorates high-fat diet-induced nonalcoholic steatohepatitis and insulin resistance by modulating hepatic IL-6/STAT3 signaling in mice by Cai X1,2,3, Fang C2,4, Hayashi S2,3, Hao S5, Zhao M6, Tsutsui H2,3, Nishiguchi S7, Sheng J8.(PubMed)
(5) One-year supplementation with a grape extract containing resveratrol modulates inflammatory-related microRNAs and cytokines expression in peripheral blood mononuclear cells of type 2 diabetes and hypertensive patients with coronary artery disease by Tomé-Carneiro J1, Larrosa M, Yáñez-Gascón MJ, Dávalos A, Gil-Zamorano J, Gonzálvez M, García-Almagro FJ, Ruiz Ros JA, Tomás-Barberán FA, Espín JC, García-Conesa MT.(PubMed)
(6) Resveratrol attenuates HMGB1 signaling and inflammation in house dust mite-induced atopic dermatitis in mice by Karuppagounder V, Arumugam S, Thandavarayan RA, Pitchaimani V, Sreedhar R, Afrin R, Harima M, Suzuki H, Nomoto M, Miyashita S,Suzuki K, Watanabe K.(PubMed)
(7) A comparison of the leaf gel extracts of Aloe ferox and Aloe vera in the topical treatment of atopic dermatitis in Balb/c mice by Finberg MJ1, Muntingh GL1, van Rensburg CE2.(PubMed)
(8) Antioxidant, anti-inflammatory, anti-apoptotic, and skin regenerative properties of an Aloe vera-based extract of Nerium oleander leaves (nae-8(®)) by Benson KF1, Newman RA2, Jensen GS1.(PubMed)