The Smoothie of Avocado, Carrot, Green Tea and Grape for Prevention and Treatment of Granulomatous mastitis

 Kyle J. Norton(Scholar, Master of Nutrients), all right reserved.

Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.

Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post

Nominated for shorty award over last 4 years

Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

The curable smoothie for reduced risk and treatment of  Granulomatous mastitis 

Yield: 2 servings (about 8 ounces each)

1/2 cup carrot

1/2 cup avocado
1/2 cup grape

1 cup green tea drink 1 cup green tea drink (Make from 4 grams(2 tea bags) of green tea, a slice of ginger and a cup of hot water lipped for 5 minutes, and set aside for cooling to room temperature)

1. Place all ingredients in a blender and puree about 1 minute

2. Blend on high speed about 1 minute or until the mixture is thick and the ice is well crushed. Add more green tea drink if needed

3. Serve immediately

Granulomatous mastitis is a very rare breast inflammatory disease of unknown etiology

The finding the natural ingredients for treatment of  Granulomatous mastitis  is considered as a dream of many scientist to replace the long usage adverse effect of conventional medicine to other organs in the body. Unfortunately, many compounds found effective in initial studying failed to confirm the potential in large sample size and multi center.

Recent reports from numbers of well known institutions insisted, intake of carrot(1) with high amount carotenoids, may be the next generation ingredient to be used on prevention and treatment of Granulomatous mastitis.

Green tea has been a precious drink in traditional Chinese culture and used exceptional in socialization for more than 4000 thousand years. Due to its commercial values and health effects, green tea now has been cultivated all over the world in suitable climate. Its phytochemical EGCG normalized LPS-induced low activities of antioxidant enzymes as well as decreased the high levels of inflammatory cytokine into the duct of mammary gland(1).

According to the Tufts University School of Medicine, green tea polyphenol epigallocatechin-3-gallate (EGCG), may also be beneficial in combinatorial treatments against active inflammatory breast cancer IBC disease or in maintenance regimens to avoid recurrence(2).

Resveratrol is a phytochemical in the class of Stilbenoids, found abundantly in skins and seed of grape may be effective in treatment of inflammatory breast disease through its antioxidant and anti-inflammatory properties(3).
According to the Northwestern University Medical School, "the expression of resveratrol anti-inflammatory, anti-platelet, and anti-carcinogenic effect through inhibited the binding of labeled estradiol to the estrogen receptor and it activated transcription of estrogen-responsive reporter genes transfected into human breast cancer cells"(4).
Vitamin derivatives α-tocopherol of vitamin E(avocado), retinol, and β-carotene of vitamin A(carrot) may be potential used a natural ingredients for treatment of inflammatory breast diseases through theirs reaction in different tissues and the genetic expression of inflammatory mediators, including breast cancer(5).

According to the Federal University of Viçosa, the effectiveness of vitamin E in ameliorated po inflammatory activities is due to its function of inflammatory mediators inh inhibition of cytokines IL-8, IL-10, and IFNγ(6).

The smoothie of Avocado, Carrot, Green Tea and Grape may hold a key in further studies in production of effective natural ingredients for prevention and treatment of any type of cystic breast disease without inducing adverse effects.

Women who are at increased risk of any of Granulomatous mastitis, due to family history,... should drink at least one cup daily. Women with any type of Granulomatous mastitis should drink no more than 4 serving daily depending to the digestive toleration.

All Forms of Arthritis are Curable
You Can Eliminate Osteoarthritis
By addressing the Underlying Causes through Clinical Trials and Studies

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to General health http://kylejnorton.blogspot.ca/p/general-health.html

Back to Kyle J. Norton Home page http://kylejnorton.blogspot.ca

References

(1) Epigallocatechin-3-gallate attenuates lipopolysaccharide-induced mastitis in rats via suppressing MAPK mediated inflammatory responses and oxidative stress by Chen J1, Xu J1, Li J1, Du L1, Chen T2, Liu P1, Peng S1, Wang M1, Song H3.(PubMed)

(2) Epigallocatechin-3-gallate inhibits stem-like inflammatory breast cancer cells by Mineva ND1, Paulson KE, Naber SP, Yee AS, Sonenshein GE.(PubMed)

(3) Resveratrol-induced apoptosis in human breast cancer cells is mediated primarily through the caspase-3-dependent pathway by Alkhalaf M1, El-Mowafy A, Renno W, Rachid O, Ali A, Al-Attyiah R.(PubMed).

(4) Resveratrol, a polyphenolic compound found in grapes and wine, is an agonist for the estrogen receptor by Gehm BD1, McAndrews JM, Chien PY, Jameson JL.(PubMed)

(5) Antioxidant vitamins and cytokines are altered in breast cancer by Abranches MV1, Mendes MC, Pena Gd, Maia YC, Ribeiro SM, Franceschini Sdo C, de Paula SO, de Freitas RN, Peluzio MC.*(PubMed)

(6) Antioxidant vitamins and cytokines are altered in breast cancer by Abranches MV1, Mendes MC, Pena Gd, Maia YC, Ribeiro SM, Franceschini Sdo C, de Paula SO, de Freitas RN, Peluzio MC.(PubMed)

Most Common Diseases of 50plus: Pulmonary vascular disease(Respiratory disease): Pulmonary embolism- The Prevention

Kyle J. Norton(Scholar and Master of Nutrients, all right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

                           Respiratory Disease

Respiratory Disease is defined as medical conditions, affecting the breathing organ and tissues including Inflammatory lung disease, Obstructive lung diseases, Restrictive lung diseases, Respiratory tract infections, trachea, bronchi, bronchioles, alveoli, the nerves and muscles breathing, etc,.

         Pulmonary vascular disease:  Pulmonary embolism


Pulmonary vascular disease is defined as a condition of blood flow to the lung’s artery is blocked suddenly due to a blood clot somewhere in the body, including pulmonary embolism, chronic thromboembolic disease, pulmonary arterial hypertension, pulmonary veno-occlusive disease, pulmonary arteriovenous malformations, pulmonary edema, etc.

                                                   

Pulmonary edema is defined as a condition of fluid accumulation in the air spaces and parenchyma of the lungs of that can lead to difficult of breathing and respiratory failure.

                                     The Prevention

Since Pulmonary embolism (PE) is a result of blockage of blood flow due to a blood clot of either in main artery of the lung or somewhere else in the body. Any Phytochemicals and antioxidants containing anti coagulation property is associated to reduced risk of the disease.
A. Diet to prevent pulmonary embolism
Since Pulmonary embolism (PE) is a result of blockage of blood flow due to a blood clot of either in main artery of the lung or somewhere else in the body. Any food containing anti coagulation property is associated to reduced risk of the disease
1. Onion and Garlic
in the testing the effect of dried garlic (Allium sativum) powder on blood lipids, blood pressure and arterial stiffness in a 12-week randomised, double-blind, placebo-controlled trial. Seventy-five healthy, normo-lipidaemic volunteers (men and women aged 40-60 years) were assigned to dried garlic powder tablets (10.8 mg alliin (3-(2-propenylsulfinyl)-L-alanine)/d, corresponding to about three garlic cloves) or placebo, showed that garlic powder was associated with a near-significant decrease (12 %) in triacylglycerol concentration (P=0.07). In conclusion, garlic powder tablets have no clinically relevant lipid-lowering and blood pressure-lowering effects in middle-aged, normo-lipidaemic individuals. The putative anti-atherosclerotic effect of garlic may be linked to risk markers other than blood lipids, according to “Effect of garlic (Allium sativum) powder tablets on serum lipids, blood pressure and arterial stiffness in normo-lipidaemic volunteers: a randomised, double-blind, placebo-controlled trial” by Turner B, Mølgaard C, Marckmann P.(41). Other in a study of “Inhibition of whole blood platelet-aggregation by compounds in garlic clove extracts and commercial garlic products.” by Lawson LD, Ransom DK, Hughes BG. posted in US National Library of Medicine National Institutes of Health, researchers found that The best garlic powder tablets were equally as active as clove homogenates whereas steam-distilled oils were 35% as active and oil-macerates (due to low content) only 12% as active. A garlic product aged many months in aqueous alcohol had no activity. For steam-distilled oils, most of the activity was due to diallyl trisulfide. For the oil-macerates, most of the activity was due largely to the vinyl dithiins. Ajoene, an exclusive component of the oil-macerates, had highest specific activity of all the compounds tested but, because of its low concentration, had only 13% of the activity of diallyl trisulfide and 3% of the activity of allicin. Compounds which may be active in vivo are discussed.
2. Ginger
In the identification of key hepatic pathways targeted by anti-obsogenic ginger phytochemicals fed to mice, found that Dietary ginger phytochemicals target cholesterol metabolism and fatty acid oxidation in mice, with consequences, according to “Ginger phytochemicals mitigate the obesogenic effects of a high-fat diet in mice: a proteomic and biomarker network analysis” by Beattie JH, Nicol F, Gordon MJ, Reid MD, Cantlay L, Horgan GW, Kwun IS, Ahn JY, Ha TY.(42). Other In the study of ginger proteases were extracted from fresh ginger rhizome by using phosphate buffer and subsequently purified by ion exchange chromatography, found that the ginger proteases exhibited a similar affinity for κ-casein and higher specificity with increasing temperature. Gel electrophoresis and mass spectra indicated that Ala90-Glu91 and His102-Leu103 of κ-casein were the preferred target bonds of ginger proteases. The milk clotting activity, affinity, and specificity toward κ-casein showed that ginger protease is a promising rennet-like protease that could be used in manufacturing cheese and oriental-style dairy foods, according to “Purification, characterization, and milk coagulating properties of ginger proteases” by Huang XW, Chen LJ, Luo YB, Guo HY, Ren FZ.(43).
3. Red pepper
In a study of Thirty-six participants (22 women and 14 men), aged 46+/-12 (mean+/-s.d.) years; BMI 26.4+/-4.8 kg/m(2), consumed 30 g/day of a chilli blend (55% cayenne chilli) with their normal diet (chilli diet), and a bland diet (chilli-free) for 4 weeks each, researchers found that Four weeks of regular chilli consumption has no obvious beneficial or harmful effects on metabolic parameters but may reduce resting heart rate and increase effective myocardial perfusion pressure time in men, according to” The effect of 4-week chilli supplementation on metabolic and arterial function in humans” by Ahuja KD, Robertson IK, Geraghty DP, Ball MJ.(44). Fermented red pepper paste(FRPP) has caused a modulation of cholesterol levels not seen in the placebo group, causing either no variation or a decrease in low-density lipoprotein and total cholesterol levels, according to the study of “Hypoxanthine levels in human urine serve as a screening indicator for the plasma total cholesterol and low-density lipoprotein modulation activities of fermented red pepper paste” by Kim Y, Park YJ, Yang SO, Kim SH, Hyun SH, Cho S, Kim YS, Kwon DY, Cha YS, Chae S, Choi HK.(45).
B. Phytochemicals and antioxidantsto prevent pulmonary embolism
1. Curcumin
In a study of `Curcumin, a major component of food spice turmeric (Curcuma longa) inhibits aggregation and alters eicosanoid metabolism in human blood platelets.`by Srivastava KC, Bordia A, Verma SK. (Source from Department of Environmental Medicine, Odense University Denmark.) posted in US National Library of Medicine National Institutes of Health, researchers found that this compound inhibited thromboxane B2 (TXB2) production from exogenous [14C] arachidonate in washed platelets with a concomitant increase in the formation of 12-lipoxygenase products. Moreover, curcumin inhibited the incorporation of [14C]AA into platelet phospholipids and inhibited the deacylation of AA-labelled phospholipids (liberation of free AA) on stimulation with calcium ionophore A23187. Curcumin’s anti-inflammatory property may, in part, be explained by its effects on eicosanoid biosynthesis.
2. Cinnamic acid
A series of novel ligustrazinyloxy-cinnamic acid derivatives were synthesized and evaluated for their inhibitory effect on adenosine diphosphate (ADP)-induced platelet aggregation in vitro,
found that compound 2e displayed the highest protective effect on the proliferation of the damaged ECV-304 cells (EC(50) = 0.020 mM), and compound 2f was the most active anti-platelet aggregation agent (EC(50) = 0.054 mM). Structure-activity relationships were briefly discussed, according to “Ligustrazine derivatives. Part 5: design, synthesis and biological evaluation of novel ligustrazinyloxy-cinnamic acid derivatives as potent cardiovascular agents” by Chen H, Li G, Zhan P, Liu X.(46)
3. Aqueous extracts of onion, garlic and ginger
Aqueous extracts of onion, garlic and ginger inhibited platelet aggregation induced by several aggregation agents, including arachidonate (AA), in a dose-dependent manner. While onion and garlic extracts were found to be weak inhibitors of platelet thromboxane synthesis, ginger extract inhibited the platelet cyclooxygenase products and this effect correlated well with its inhibitory effects on the platelet aggregation induced by the above aggregation agents(47).

All Forms of Arthritis are Curable

You Can Eliminate Osteoarthritis

By addressing the Underlying Causes through Clinical Trials and Studies

Ovarian Cysts And PCOS Elimination

Holistic System In Existence That Will Show You How To

Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Super foods Library, Eat Yourself Healthy With The Best of the Best Nature Has to Offer

Sources
(41) http://www.ncbi.nlm.nih.gov/pubmed/15522140
(42) http://www.ncbi.nlm.nih.gov/pubmed/21954187
(43) http://www.ncbi.nlm.nih.gov/pubmed/21524515
(44) http://www.ncbi.nlm.nih.gov/pubmed/16929238
(45) http://www.ncbi.nlm.nih.gov/pubmed/20797477
(46) http://www.ncbi.nlm.nih.gov/pubmed/21993151
(47) http://www.ncbi.nlm.nih.gov/pubmed/6440548

Most Common Disease of50plus: The Clinical trials and Studies of Musculo-Skeletal disorders(MSDs) - Rheumatoid Arthritis: The Signs and Symptoms

Kyle J. Norton (Scholar)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

Musculoskeletal disorders (MSDs) are medical condition mostly caused by work related occupations and working environment, affecting patients’ muscles, joints, tendons, ligaments and nerves and developing over time. A community sample of 73 females and 32 males aged 85 and over underwent a standardised examination at home. Musculoskeletal pain was reported by 57% of those interviewed. A major restriction of joint movement range was frequent in the shoulder but uncommon in other joints(1).

Types of Musculo-Skeletal disorders in elder(2)
1. Osteoarthritis
2. Gout
3. Rheumatoid Arthritis
4. Polymalagia Arthritis
5. Cervical myleopathy and spinal canal stenosis
6. Osteoporosis
7. Low back pain
8. Fibromyalgia


                      Rheumatoid Arthritis

Rheumatoid Arthritis is defined a chronic disorder as a result of inflammation, affecting mostly the flexible (synovial) joints and tissues and organs in the body. The disease affects more women than men and generally occurs after the ages of 40, causing diminished quality of life of many elders(1). According to CDC, Musculoskeletal disorders (MSDs) affects over 52 millions of adults in the US alone, including 294,000 children under age 18 with some form of arthritis or rheumatic conditions(2). Rheumatoid Arthritis can induced bone loss through elevating bone resorption without increasing bone formation(4). A cross-sectional population-based study of 1042 patients with rheumatoid arthritis showed that RA patients had an increased risk of death from various causes(4a).

                      The Signs and Symptoms


1. The feet and joints
Patient with rheumatoid arthritis (RA) often associate to valgus deformities of the feet and deformities of gait due to body function in effort to support the collapsing longitudinal arch of the foot(3). According to Dr. Brooks F and Dr. Hariharan K., feet demortities, effecting over 90% of the patient, behind only the hand, leading to painful callosities and dislocation of the metatarsophalangeal joints(5). Because of its severity, regardless to "....pharmacological management of rheumatoid arthritis and its impact upon disease progression, forefoot deformity and pain remain common manifestations requiring reconstruction from orthopadic surgeons" Dr. Amin A. and the reaserch team at the Royal National Orthopaedic Hospital, said(6).
In fact, the prevalence of deformations of hands, feet and gait can be seen among patient with rheumatoid arthritis among aging population may be depending to the severity and time factors which can lead to enormous pain and swelling of the ankle of which correlated weakly but statistically significantly with limitation and disability(7). The Jyväskylä Central Hospital, suggested that radiographic damage of hand and foot joints, and the number of tender and swollen joints are frequent found in patient with Rheumatoid Arthritis(8)(9).

2. The gait
Dr. Weiss RJ. and the research team at the Karolinska Institutet, showed that the kinematic and kinetic gait changes in rheumatoid arthritis (RA) patients are the result of a significant reduction in joint motions, joint moments, such as decreased hip flexion-extension range, hip abduction, knee flexion-extension range,...(9). The valgus deformities of the feet in patient withRA may be the main contribution to deformities of gait, including revealed decreases in velocity, stride length, and single-limb-support time(10). Used as characterise dysfunction of the lower limb and foot in people, gait also expressed its effects mainly in RA's patient with conditions of of a slower walk, longer double support time, and avoidance of extreme positions(11).


3. The hands
The affects of deformation of RA's hands can be described through the defects of bone ankylosis as a result of bone damage of the prolonged onset of the disease(12). These deformities of hand and wrist and small peripheral joints (such as fingers and wrist) due to chronic inflammation can be treated by transelectrical nerve stimulation, the University of Ottawa suggested(14).
According to the joint study lead by the University of Warwick, strengthening and stretching have been found effectively in reduced pain and dysfunction of the hands and/or wrists in RA patient with stable medication for at least 3 months(13)

4. The Muscle strength
The effects of muscle strength in patient with RA may contribute to the prevalence of functional limitations physically of that cdan effects daily living and quality of life. Dr. Häkkinen A and the research team at Jyväskylä Central Hospital, suggested that 2-year program of strength training showed a statistically significant improvement in clinical disease activity parameters, walking speed and physical function(15). Some researchers suggested that muscle strength was found inversely and independently associated with all-cause mortality, including the levels of physical activity or even cardiorespiratory fitness(16).
Dr. Brodin N and Dr. Swärdh said"... short-term land-based aerobic and strengthening exercise on moderate to high intensity results in positive effects on oxygen uptake and muscular strength, but not pain,..." (17).of that may be necessary for patient with RA.

5. Rheumatoid nodules
Rheumatoid nodules, lump on the skin, closed to the joint have been found to affect the joints of patients with rheumatoid nodules(18). Treatment of rheumatoid nodules are necessary in odd cases if the patient are experiencing pain or interference of mechanical function, according to Dr. Tilstra JS and Dr.Lienesch DW.(19). Use of methotrexate (MTX) in patient with RA may accelerate the occurance of nodulosis in the fingers. but nodules will be resolved after methotrexate was discontinued and recurred after methotrexate was reintroduced(20).
5. Conjunctival nodule
Although is rare in patients with rheumatoid arthritis, the appreance of the nodules may exhibit the
severity of the underlying disease, according to the Tehran University of Medical Sciences(21), including Pityriasis Lichenoides et Varioliformis Acuta(22), Epstein-Barr virus(23)


6. Morning stiffness
Morning stiffness, as a marker of inflammatory activity in reflecting functional disability and pain is a very common symptoms of patients in early rheumatoid arthritis(24). Use of glucocorticoid is found effectively in pain relief over 70 percent of patient with RA(25).
According to the Charité University Medicine, in a 12-week, multicentre, randomised, double-blind trial, 288 patients with active rheumatoid arthritis, treatment of modified-release prednisone exhibited a clinically relevant reduction of morningstiffness of the joint in comparison of immediate-release prednisone(26).


7. Quality of life
7.1. Physical disability
Although psychological distress and physical disability have been decreased with the cautious approach with respect to prescribing medication and physical exercise progressed toward RA patient(27), but tools necessary to measure RA disease activity are often incomplete, imprecise, or rely on a combination of physician and patient subjective evaluations(28)
Dr. Motl RW and Dr. McAuley E.said" The rationale and the associated onset of chronic disease conditions that influence function, disability, and quality of life (QOL) is embedded in the "Graying of America""(29), including patient with RA.

7.2. Concurrent psychiatric disorders
Concurrent psychiatric disorders, such as depression or anxiety in patient with Rheumatoid Arthritis is found to associate to poor quality of life, according to Dr. Mok C, and the scientists at the Tuen
Mun Hospital(30). Patients with RA is found to associate to Neurologic (N) and psychiatric (P) syndromes including depression and anxiety and symptoms of cognitive dysfunction, etc.,....of that induced poorer quality of life, according to the Lby the SF-36 and fatigue by a 10 point Likert scale(32).
Dr. Arnold LM said" Chronic widespread pain is associated with several medical and psychiatric disorders,....,careful and comprehensive differential diagnosis must be performed to ensure a correct diagnosis before an appropriate treatment can be selected"(31).

Arthritis Is Curable
You Can Eliminate Osteoarthritis
By addressing the Underlying Causes through Clinical Trials and Studies

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Super foods Library, Eat Yourself Healthy With The Best of the Best Nature Has to Offer recommended by Kyle J. Norton

Back to Kyle J. Norton Home page http://kylejnorton.blogspot.ca

References
(1) 8 Areas of Age-Related Change(NIH)
(2) Arthritis-Related Statistics(CDC)
(3) Valgus deformities of the feet and characteristics of gait in patients who have rheumatoid arthritis by Keenan MA1, Peabody TD, Gronley JK, Perry J.(PubMed)
(4) Serum Sclerostin Level Among Egyptian Rheumatoid Arthritis Patients: Relation to Disease Activity ,Bone Mineral Density and Radiological Grading by Mehaney DA, Eissa M, Anwar S, El-Din SF(PubMed)
(4a) Death rates and causes of death in patients with rheumatoid arthritis: a population-based study by Sihvonen S1, Korpela M, Laippala P, Mustonen J, Pasternack A(PubMed)
(5) The rheumatoid forefoot by Brooks F1, Hariharan K.(PubMed)
(6) Rheumatoid forefoot reconstruction by Amin A1, Cullen N, Singh D.(PubMed)
(7) We should not forget the foot: relations between signs and symptoms, damage, and function in rheumatoid arthritis by Baan H1, Drossaers-Bakker W, Dubbeldam R, van de Laar M.(PubMed)
(8) Pain and joint mobility explain individual subdimensions of the health assessment questionnaire (HAQ) disability index in patients with rheumatoid arthritis by Häkkinen A1, Kautiainen H, Hannonen P, Ylinen J, Arkela-Kautiainen M, Sokka T.(PubMed)
(9) Gait pattern in rheumatoid arthritis by Weiss RJ1, Wretenberg P, Stark A, Palmblad K, Larsson P, Gröndal L, Broström E.(PubMed)
(10) Valgus deformities of the feet and characteristics of gait in patients who have rheumatoid arthritis by Keenan MA1, Peabody TD, Gronley JK, Perry J.(PubMed)
(11) Gait analysis of the lower limb in patients with rheumatoid arthritis: a systematic review by Baan H1, Dubbeldam R, Nene AV, van de Laar MA.(PubMed)
(12) Ankylosis of the wrist bones in patients with rheumatoid arthritis: a study with extremity-dedicated MRI by Barbieri F1, Zampogna G1, Camellino D1, Paparo F2, Cutolo M1, Garlaschi G3, Cimmino MA4.(PubMed)
(13) Strengthening And stretching for Rheumatoid Arthritis of the Hand (SARAH). A randomised controlled trial and economic evaluation by Williams MA1, Williamson EM1, Heine PJ1, Nichols V1, Glover MJ2, Dritsaki M2, Adams J3, Dosanjh S1, Underwood M1, Rahman A4, McConkey C1, Lord J1,Lamb SE1.(PubMed)
(14) Transcutaneous electrical nerve stimulation (TENS) for the treatment of rheumatoid arthritis in the hand by Brosseau L1, Judd MG, Marchand S, Robinson VA, Tugwell P, Wells G, Yonge K(PubMed)
(15) A randomized two-year study of the effects of dynamic strength training on muscle strength, disease activity, functional capacity, and bone mineral density in early rheumatoid arthritis by Häkkinen A1, Sokka T, Kotaniemi A, Hannonen P.(PubMed)
(16) Muscular strength as a strong predictor of mortality: A narrative review by Volaklis KA1, Halle M2, Meisinger C3.(PubMed)
(17) Personer med reumatoid artrit bör uppmanas till fysisk aktivitet.[Article in Swedish]by Brodin N1, Swärdh E1.(PubMed)
(18) Microchimerism in the rheumatoid nodules of patients with rheumatoid arthritis by Chan WF1, Atkins CJ, Naysmith D, van der Westhuizen N, Woo J, Nelson JL.(PubMed)
(19) Rheumatoid Nodules by Tilstra JS1, Lienesch DW2.(PubMed)
(20)Accelerated cutaneous nodulosis during methotrexate therapy in a patient with rheumatoid arthritis by Williams FM1, Cohen PR, Arnett FC.(PubMed)
(21) Conjunctival nodule in rheumatoid arthritis by Kheirkhah A1, Amoli FA, Azari AA, Molaei S, Roozbahani M.(PubMed)
(22) Conjunctival Inflammatory Nodule in a Patient with Pityriasis Lichenoides et Varioliformis Acuta by Elad Moisseiev* and David Varssano(PMC)
(23) Conjunctival lymphocytic nodule associated with the Epstein-Barr virus by Gardner BP1, Margolis TP, Mondino BJ.(PubMed)
(24) Morning stiffness in patients with early rheumatoid arthritis is associated more strongly with functional disability than with joint swelling and erythrocyte sedimentation rate by Yazici Y1, Pincus T, Kautiainen H, Sokka T.(PubMed)(25) Improvement Thresholds for Morning Stiffness Duration in Patients Receiving Delayed- Versus Immediate-Release Prednisone for Rheumatoid Arthritis by Buttgereit F, Kent JD, Holt RJ, Grahn AY, Rice P, Alten R, Yazici Y.(PubMed)
(26) Efficacy of modified-release versus standard prednisone to reduce duration of morning stiffness of the joints inrheumatoid arthritis (CAPRA-1): a double-blind, randomised controlled trial by Buttgereit F1, Doering G, Schaeffler A, Witte S, Sierakowski S, Gromnica-Ihle E, Jeka S, Krueger K, Szechinski J, Alten R.(PubMed)
(27) Change of psychological distress and physical disability in patients with rheumatoid arthritis over the last two decades by Overman CL1, Jurgens MS, Bossema ER, Jacobs JW, Bijlsma JW, Geenen R.(PubMed)
(28) Optimizing Rheumatoid Arthritis Therapy: Using Objective Measures of Disease Activity to Guide Treatment by Owens GM1(PubMed)
(29) Physical activity, disability, and quality of life in older adults by Motl RW1, McAuley E.(PubMed)
(30) Concurrent psychiatric disorders are associated with significantly poorer quality of life in patients with rheumatoid arthritis by Mok CC1, Lok EY, Cheung EF(PubMed)
(31) Pain and the brain: chronic widespread pain by Arnold LM1(PubMed)

The smoothie of Alfalfa Sprouts Juice, Green Tea and Honey for Prevention and Treatment of Vaginal Bleeding in Menopause caused by cervical Polyps

Kyle J. Norton(Scholar, Master of Nutrients), all right reserved.
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

The finding of a natural source for reduced risk and treatment of Vaginal Bleeding in Menopause caused by Polyps has encountered many obstacles, many ingredients showed initially the promising result in animal studies have not produced same potentials in either large sample size and mutli centers human trials.

Scientists in some well known institutions may have found the therapeutic and potential ingredients from natural sources(Green tea and grape) for reduced risk and treatment of Vaginal Bleeding in Menopause caused by Polyps.

Abnormal vaginal bleeding is a bleeding when you do not suppose to such as menopause, pregnancy or when your menstruation is lighter or heavier than it should be.
Polyps is a small and benign growth, with a stalk, protruding from an epithelial tissue.

The smoothie for reduced risk and treatment of Vaginal Bleeding in Menopause caused by cervical Polyps
Yield: 2 servings (about 8 ounces each)
3/4 cup alfalfa sprouts juice
1/4 cup honey for taste
1 cup green tea drink (Make from 4 grams of green tea, a slice of ginger and a cup of hot water lipped for 5 minutes, and let cool to room temperature)

1. Place all ingredients in a blender and puree about 1 minute
2. Blend on high speed about 1 minute or until the mixture is thick and the ice is well crushed. Add more green tea drink if needed

3. Serve immediately

Cervical polyps are small, elongated tumors that grow on the cervix caused by hormone imbalance and chronic inflammation of cervix. According to the statistic, the prevalence of any abnormality within a cervical polyp is significantly lower in postmenopausal, compared with premenopausal women(1).
Phytoestrogen, such as  isoflavonoids found in legume exhibited estrogenic and anti estorgenic effects depending to the levels of estrogen in women  may inhibit the induction of cervical polyps caused by hormone imbalance(2).
In menopausal women, estrogen deficiency after menopause not only accelerated the redox imbalance and insulin signaling but also induced oxidative stress (OS) and insulin resistance (IR), intake of isoflavones from varies sources including may exhibited estrogen balancing effect in ameliorated risk of oxidative stress (OS) and insulin resistance (IR)(3).

Dr. Kurzer MS and Dr. Xu X. Said, " phytoestrogens include isoflavones.......... A number of these compounds have been identified in fruits, vegetables, and whole grains commonly consumed by humans.....(such as) alfalfa sprouts,,..(through) proposed mechanisms include estrogenic and antiestrogenic effects"(4).

Green tea has been a precious drink in traditional Chinese culture and used exceptional in socialization for more than 4000 thousand years. Due to its commercial values and health effects, green tea now has been cultivated all over the world in suitable climate. Its phytochemicals such as polyphenols (GTP) have shown to inhibit over expression of chronic inflammation of pro inflammatory cytokine TNF-α.(5) in chronic inflammatory diseases(6).

In animal model, alcoholic extracts of green tea (AE) displayed anti-inflammatory and analgesic effects against chronic inflammatory disorders, the UNIFOR, Fortaleza, insisted(7).

The effectiveness of  Alfalfa Sprouts Juice and Green Tea may serve as cornerstones of pharmaceutical target for further studies in production of a potential medication for for Reduced Risk of Consequences of  Cervical Polyps with little or no adverse effects.

Women who are pregnancy may want to stop drinking excessively. Otherwise, intake of
Smoothie of  Alfalfa Sprouts Juice and Green Tea may Reduced Risk and treatment of  Cervical Polyps.
Life style and dietary patter change are recommended.

All Forms of Arthritis are Curable
You Can Eliminate Osteoarthritis
By addressing the Underlying Causes through Clinical Trials and Studies


Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months


Super foods Library, Eat Yourself Healthy With The Best of the Best Nature Has to Offer

References
(1) Cervical polyps in postmenopausal women: is there a difference in risk? by Schnatz PF1, Ricci S, O'Sullivan DM.(PubMed)
(2) Phytoestrogen content and estrogenic effect of legume fodder by Saloniemi H1, Wähälä K, Nykänen-Kurki P, Kallela K, Saastamoinen I.(PubMed)
(3) Amelioration of oxidative stress and insulin resistance by soy isoflavones (from Glycine max) in ovariectomized Wistar rats fed with high fat diet: the molecular mechanisms by Sankar P1, Zachariah B2, Vickneshwaran V3, Jacob SE4, Sridhar MG3(PubMed)
(4) Dietary phytoestrogens by Kurzer MS1, Xu X.(PubMed)
(5) Protective actions of green tea polyphenols and alfacalcidol on bone microstructure in female rats with chronicinflammation by Shen CL1, Yeh JK, Samathanam C, Cao JJ, Stoecker BJ, Dagda RY, Chyu MC, Wang JS.(PubMed)
(6) Green tea polyphenols attenuate deterioration of bone microarchitecture in female rats with systemic chronic inflammation by Shen CL1, Yeh JK, Samathanam C, Cao JJ, Stoecker BJ, Dagda RY, Chyu MC, Dunn DM, Wang JS.(PubMed)
(7) Evaluation of the anti-inflammatory and analgesic effects of green tea (Camellia sinensis) in mice. by Mota MA1, Landim JS1, Targino TS1, Silva SF1, Silva SL1, Pereira MR1.(PubMed)

Most Common Diseases of 50plus: Pulmonary vascular disease(Respiratory disease): Pulmonary embolism- The Complications and diseases associated to

Kyle J. Norton(Scholar and Master of Nutrients, all right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

                           Respiratory Disease

Respiratory Disease is defined as medical conditions, affecting the breathing organ and tissues including Inflammatory lung disease, Obstructive lung diseases, Restrictive lung diseases, Respiratory tract infections, trachea, bronchi, bronchioles, alveoli, the nerves and muscles breathing, etc,.

         Pulmonary vascular disease:  Pulmonary embolism


Pulmonary vascular disease is defined as a condition of blood flow to the lung’s artery is blocked suddenly due to a blood clot somewhere in the body, including pulmonary embolism, chronic thromboembolic disease, pulmonary arterial hypertension, pulmonary veno-occlusive disease, pulmonary arteriovenous malformations, pulmonary edema, etc.

                                                   

Pulmonary edema is defined as a condition of fluid accumulation in the air spaces and parenchyma of the lungs of that can lead to difficult of breathing and respiratory failure.

Complications and diseases associated to pulmonary embolism

C.1. Complications
1. Endomyocarditis
Pulmonary embolism (PE) is a significant cause of morbidity and mortality. In a recent study in patients with PE, an increased level of macrophages was found in the right ventricle. In teh study to evaluate the presence of inflammatory cells, myocytolysis and intracavitary thrombi in the left and right ventricle of patients who died because of PE as a putative new source of heart failure, showed that in patients with PE, endomyocarditis and intracavitary thrombi in the left and right ventricle were found. These abnormalities may be an additional new explanation for the observed cardiac enzyme release and functional abnormalities of the heart in these patients and may contribute to the morbidity and mortality of the disease(19).
2. Other complications
In a study by the the University Medical Center Mannheim, of 65 patients with confirmed acute PE, hs-cTnI and D-dimer values were measured. Adverse clinical outcome was defined as cardiogenic shock, cardiopulmonary resuscitation, mechanical ventilation, vasopressor therapy, thrombolysis, catheter intervention or mortality within 60 days of PE. Patients with acute PE and serum hs-cTnI values >0.1 ng/ml showed significantly higher D-dimer concentrations (P= 0.0467) and a 5-fold increased risk of an adverse clinical outcome [odds ratio (OR), 4.9; 95% confidence interval (CI), 1.28-18.66; P=0.0235] compared with patients with acute PE and hs-cTnI values <0.1 ng/ml(20).
C.2. Diseases associated to Pulmonary embolism (PE)
1. Low blood pressure
Massive pulmonary embolism (PE) is characterized by systemic hypotension (defined as a systolic arterial pressure < 90 mm Hg or a drop in systolic arterial pressure of at least 40 mm Hg for at least 15 min which is not caused by new onset arrhythmias) or shock (manifested by evidence of tissue hypoperfusion and hypoxia, including an altered level of consciousness, oliguria, or cool, clammy extremities). Massive pulmonary embolism has a high mortality rate despite advances in diagnosis and therapy, according to teh study by the New York Medical College(21).
2. Deep Vein Thrombosis (DVT)
The average annual incidence of deep vein thrombosis alone was 48 per 100,000, while the incidence of pulmonary embolism with or without deep vein thrombosis was 23 per 100,000. The incidence rates of deep vein thrombosis and pulmonary embolism increased exponentially with age, according to the University of Massachusetts Medical School(22).
3. Congenital heart disease
Long-term complications of congenital heart diseases include rhythm disturbances, pulmonary hypertension, or heart failure are frequent, despite optimal care. Acute complications like arrhythmias, infective endocarditis, cerebral events, cerebral abscesses, aortic dissection, pulmonary embolism, and bleeding(23)
4. Pleural Effusion
Pulmonary embolism (PE) is the fourth cause of pleural effusions, after pneumonia, neoinfiltrates and tuberculosis, according to the study by the Institute of Lung Diseases and Tuberculosis(24).
5. Pulmonary edema
There is a report of a case of severe pulmonary embolism in a 37 years old man admitted to the intensive care unit for severe acute respiratory failure. The presenting signs and symptoms were typical for severe pulmonary oedema(25).
6. Thromboembolic pulmonary hypertension (CTEPH)
Incomplete resolution of acute pulmonary embolism (PE) is frequently observed after acute PE and may rarely result in chronic thromboembolic pulmonary hypertension (CTEPH)(26).
7. Pulmonary hypertension
Incomplete resolution of acute pulmonary embolism (PE) is frequently observed after acute PE and may rarely result in chronic thromboembolic pulmonary hypertension (CTEPH). According to the study by the Leiden University Medical Center, CTEPH is associated with a poor prognosis if left untreated. Therefore, the diagnostic approach of CTEPH aims at assessing the location and extent of the embolic obstruction, establishing the operability and prognosis of the patients and ruling out other variations of pulmonary hypertension with distinct indicated treatment(27).
8. Chronic obstructive pulmonary disease and chronic renal failure
There is a report of a 75-year-old man affected by a chronic obstructive pulmonary disease and chronic renal failure admitted to our emergency department for dyspnea and interscapular stabbing pain. Chest radiography showed diffuse parenchymal consolidation in the lower right lung with bronchiectasis, but the treatment for infection disease did not improve the clinical conditions of the patient. According to Wells score indicating an intermediate risk for pulmonary embolism, chest ultrasonography that showed ultrasonographic patterns of thromboembolism(28).

All Forms of Arthritis are Curable

You Can Eliminate Osteoarthritis

By addressing the Underlying Causes through Clinical Trials and Studies

Ovarian Cysts And PCOS Elimination

Holistic System In Existence That Will Show You How To

Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Super foods Library, Eat Yourself Healthy With The Best of the Best Nature Has to Offer

Sources
(19) http://www.ncbi.nlm.nih.gov/pubmed/17646195
(20) http://www.ncbi.nlm.nih.gov/pubmed/23403884
(21) http://www.ncbi.nlm.nih.gov/pubmed/23319967
(22) http://www.ncbi.nlm.nih.gov/pubmed/2025141
(23) http://www.ncbi.nlm.nih.gov/pubmed/23318541
(24) http://www.ncbi.nlm.nih.gov/pubmed/23425873
(25) http://www.ncbi.nlm.nih.gov/pubmed/6704566
(26) http://www.ncbi.nlm.nih.gov/pubmed/23607029
(27) http://www.ncbi.nlm.nih.gov/pubmed/22648493
(28) http://www.ncbi.nlm.nih.gov/pubmed/22154162

Most Common Disease of50plus: The Clinical trials and Studies of Musculo-Skeletal disorders(MSDs) - Osteoarthritis: Treatment In herbal and traditional Chinese medicine - The herbal Formulas

Kyle J. Norton (Scholar)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

Musculoskeletal disorders (MSDs) are medical condition mostly caused by work related occupations and working environment, affecting patients’ muscles, joints, tendons, ligaments and nerves and developing over time. A community sample of 73 females and 32 males aged 85 and over underwent a standardised examination at home. Musculoskeletal pain was reported by 57% of those interviewed. A major restriction of joint movement range was frequent in the shoulder but uncommon in other joints(1).

Types of Musculo-Skeletal disorders in elder(2)
1. Osteoarthritis
2. Gout
3. Rheumatoid Arthritis
4. Polymalagia Arthritis
5. Cervical myleopathy and spinal canal stenosis
6. Osteoporosis
7. Low back pain
8. Fibromyalgia



                                                      Osteoarthritis


Osteoarthritis (OA), a form of arthritis, is defined as a condition of as a result of aging causes of wear and tear on a joint, affecting over 25 million people in the United States in alone. University of Porto Medical School indicated that one must understand the differences in prevalence and incidence estimates of osteoarthritis (OA), according to case definition, in knee, hip and hand joints(3).
The characteristics of osteoarthritis are aching pain(5), stiffness(6), or difficulty of moving the joint or joints(7). The pain usually gets worse in change of weather, at night and in the advanced diseases, the pain can occur even at rest(8). Today management of osteoarthritis (OA) focuses on pain relief and improved physical function through pharmacological, non pharmacological, and surgical treatments(4).

                           The Treatment

B. In herbal and traditional Chinese medicine perspective
B.2.2. Herbal and traditional Chinese medicine formulas
1. Phytodolor (STW 1)
Phytodolor, a fixed herbal formulation containing alcoholic extracts of aspen leaves and bark (Populus tremula), common ash bark (Fraxinus excelsior), and golden rod herb (Solidago virgaurea), has been used for treatment in painful inflammatory or degenerative rheumatic diseases(483), probably due to its antiinflammatory, antioedematous, antioxidative and analgesic properties(483).
According to the University Hospital Zurich, in the review of the data base of randomized controlled trials (RCTs), STW1 can be used as non-steroidal anti-inflammatory drugs (NSAIDs) in relieving pain in patient with musculoskeletal disorders, including osteoarthritis(484). DR. Gundermann KJ and Dr., Müller J. in the study of painful inflammatory or degenerative rheumatic diseases, said" Phytodolor (STW 1) is a reasonable alternative to NSAIDs and to cyclooxygenase(COX)-2-inhibitors such as rofecoxib"(483) and "STW 1 has a high drug safety"(483) with little side effects(486).
The formula although is found to be effective in some extension in treating pain for patient with MD, some research suggested that most popular CAM therapies for pain from arthritis-related conditions, should be gone through additional high quality research, especially for herbals and homeopathy(485).


2. Reumalex
Reumalex, is a herbal medicine formula containing 100 mg White Willow bark, 40 mg, Guaiacum Resin BHP, 35 mg Black Cohosh, 25 mg Extract of Sarsparilla and 17 mg Extract of Poplar Bark. In a 2 months without cross-over study, in 82 subjects with chronic arthritic pain, Dr. Mills SY and the research team at the University of Exeter showed that Reumalex, the herbal medicine improved the pain symptoms through its mild analgesic effect(487).

3. Gitadyl
Gitadyl is another herbal medicine formula containing 110 mg feverfew, 90 mg American aspen and 60 mg milfoil(488). According to a double-blind, randomized, cross-over study conducted by Hvidovre Hospital, in comparison of the effectiveness of herbal formula Gitadyl and conventional medicine ibuprofen(490) in patients with osteoarthritis, researchers found that Gitadyl can be used for treatment of such as reduced pain(488) and working ability(488) of patient with osteoarthritis who are prone to bleeding or who develop gastrointestinal (GI) symptoms from NSAIDs(489),

4. SKI306X
SKI306X, is a herbal formula containing Clematis mandshurica (CM), Prunella vulgaris (PV), and Trichosanthes kirilowii (TK),
According to the study by the Hanyang University Hospital for Rheumatic Diseases, SKI3006X, reduced pain and improve physical performance(498) by inhibited degradation of glycosaminoglycan (GAG) through its expression on anti inflammatory(497)(499) and analgesic(499)properties in interleukin (IL)-1β induced gene expression in human OA(497). In a a double-blind placebo controlled study of 96 patients with classical osteoarthritis of the knee, SKI 306X at 100mm demonstrated its clinical efficacy in comparison to placebo, according to the Chung-Ang University(500).


5. Duhuo Jisheng Wan (DJW)
Duhuo Jisheng Wan (DJW)or Duhuo Jisheng Tang (DJT) is a Chinese herbal formula containing over 18 individual herbs(501) has been used for treatment of knee osteoarthritis with limit scientific evidence(502), according to the Nestlé Research Center(503), but in a randomized, double-blind, double-dummy, controlled trial of a total of 200 patients suffering from OA of the knee, researcher at the Chiang Mai University, showed to improve walking pain, standing pain and stiffness, with approximately 30% of patients in both groups experienced mild adverse events(504).
The Taipei City Hospital study of Duhuo Jisheng Wan(DJW) also supported the effectiveness of the herbal formula in reduced pain, stiffness and improved physical functioning as well as other symptoms of degenerative osteoarthritis of the knee(502).

6. Huo-Luo-Xiao-Ling (HLXL) Dan
Huo-Luo-Xiao-Ling (HLXL) Dan is a Chinese herbal formula containing Ru Xiang (Boswellia carterii Birdw.), Mo Yao (Commiphora myrrha Engl.), Dang Gui (Angelica sinensis (Oliv.) Diels) and Dan Shen (Salvia miltiorrhiza Bge), used over thousands of year in Chinese history for treatment in alleviating pain caused rheumatoid arthritis (RA) and other inflammatory disorders(505)(508). On a Phase II clinical trial at Kernan Hospital of the University of Maryland School of Medicine, the herbal formula moderately inhibited hyperanalgesic (severe pain killing)(508) with no side effect in comparison to placebo(506) in patient with osteoarthritis OA. The phase II clinical trials also showed treatment of HLXL-Dan was not superior to placebo in pain relief or functional improvement in patients with knee OA if use only in 8 weeks(507).


7. Si Miao Fang
SI Miao Fang is a herbal formula comprised of Phellodendri Chines Cortex, Atractylodis rhizoma, Coicis Semen, and Achyranthis bidentatae Radix used in traditional Chinese medicine for pain relief, due to inflammation and and analgesics(509) in patient with gouty arthritis(510) and rheumatoid arthritis(511). In osteoarthritic rat model, according to the China Academy of Chinese Medical Sciences, herbal formula inhibited expression of matrix metalloproteinases (MMPs) -3 and -13 and aggrecanases (ADAMTS) -4 and -5, induced OA causes of cartilage matrix degradation, by increasing proteoglycan and collagen content(512) through its interferes with secretion of pro-inflammatory cytokines and inflammatory mediators(512).


8. Other Chinese herbal prescription for treatment of OA, according to Osteoporosis & Osteoarthritis in TCM Therapy by Chun Yi, Lu O.M.D., LAc. may also include Shu Jing Huo Xue Tang
Shu Jing Huo Xue Tang can be prescribed for treatment of patient with osteoarthritis caused by blood stagnation and blood stasis induced chronic pain syndromes, through its effect in suppressed neuropathic pain behaviors(514), including adjuvant arthritis(515). According to the article of Osteoporosis & Osteoarthritis in TCM Therapy by Chun Yi, Lu O.M.D., LAc(513), the formula can also used for treatment of OA patient due to the effects in induced blood downward movement, strengthened the movement of bone, relived pain, improved joint function and inhibited inflammation causes of swollen of the joint lining and (513).


Arthritis Is Curable
You Can Eliminate Osteoarthritis
By addressing the Underlying Causes through Clinical Trials and Studies

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Super foods Library, Eat Yourself Healthy With The Best of the Best Nature Has to Offer recommended by Kyle J. Norton

Back to Kyle J. Norton Home page http://kylejnorton.blogspot.ca


References
(1) Prevalence of rheumatic symptoms, rheumatoid arthritis, ankylosing spondylitis, and gout in Shanghai, China: a COPCORD study by Dai SM1, Han XH, Zhao DB, Shi YQ, Liu Y, Meng JM.(PubMed)
(2) Musculoskeletal Disorders in the Elderly by Ramon Gheno, Juan M. Cepparo, Cristina E. Rosca,1 and Anne Cotten(PMC)
(3) The effect of osteoarthritis definition on prevalence and incidence estimates: a systematic review by Pereira D1, Peleteiro B, Araújo J, Branco J, Santos RA, Ramos E.(PubMed)
(4) Effect of therapeutic aquatic exercise on symptoms and function associated with lower limb osteoarthritis: systematic review with meta-analysis by Waller B1, Ogonowska-Slodownik A2, Vitor M3, Lambeck J4, Daly D5, Kujala UM6, Heinonen A7.(PubMed)
(5) Effects of therapeutic ultrasound on pain, physical functions and safety outcomes in patients with kneeosteoarthritis: A systematic review and meta-analysis by Zhang C1, Xie Y2, Luo X3, Ji Q3, Lu C3, He C4, Wang P3.(PubMed)
(6) Oral intake of purple passion fruit peel extract reduces pain and stiffness and improves physical function in adult patients with knee osteoarthritis by Farid R1, Rezaieyazdi Z, Mirfeizi Z, Hatef MR, Mirheidari M, Mansouri H, Esmaelli H, Bentley G, Lu Y, Foo Y, Watson RR.(PubMed)
(7) Functional ability, mobility, and pain before and after knee replacement in patients aged 75 and older: a cross-sectional study by Limnell K1, Jämsen E, Huhtala H, Jäntti P, Puolakka T, Jylhä M.(PubMed)
(8) The symptoms of OA and the genesis of pain by David J. Hunter, MBBS PhD,1,2 Jason J. McDougall, BSc PhD,3 and Francis J. Keefe4(PubMed)

(483) Phytodolor--effects and efficacy of a herbal medicine by Gundermann KJ1, Müller J.(PubMed)
(484) Phytodolor® in musculoskeletal disorders: re-analysis and meta-analysis by Uehleke B1, Brignoli R, Rostock M, Saller R, Melzer J.(PubMed)
(485) Selected CAM therapies for arthritis-related pain: the evidence from systematic reviews.
Soeken KL1.(PubMed)
(486) EFFECT OF A PROPRIETARY HERBAL MEDICINE ON THE RELIEF OF CHRONIC ARTHRITIC PAIN: A DOUBLE-BLIND STUDY by S. Y. MILLS, R. K. JACOBY*, M. CHACKSFIELD and M. WILLOUGHBY(Rheumatology)
(487) Effect of a proprietary herbal medicine on the relief of chronic arthritic pain: a double-blind study by Mills SY1, Jacoby RK, Chacksfield M, Willoughby M.(PubMed)
(488) [Gitadyl versus ibuprofen in patients with osteoarthrosis. The result of a double-blind, randomized cross-over study].[Article in Danish]by Ryttig K1, Schlamowitz PV, Warnøe O, Wilstrup F.(PubMed)
(489) Gitadyl versus ibuprofen in patients with osteoarthritis: a double-blind, randomized, cross-over study of clinical efficacy and effects on platelets and PMNs by Mieszczak CI1, Kharazmi A, Rein J, Winther K.(PubMed)
(490) [Gitadyl versus ibuprofen].[Article in Danish] by [No authors listed](PubMed)

(491) Danshen prevents articular cartilage degeneration via antioxidation in rabbits with osteoarthritis by Bai B1, Li Y2.(PubMed)
(492) Veterinary Herbal Medicine By Susan G. Wynn, Barbara Fougère, page 349.
(493) Dan Shen (Salvia miltiorrhiza) in Medicine: Volume 2. Pharmacology ..., Volume 2 edited by Xijun Yan
(494) [Comparative analysis on composition principles of traditional Chinese medicine prescriptions for osteoporosis and osteoarthritis].[Article in Chinese] by Zheng ZR, Tang SH.(PubMed)
(495) Complementary and Alternative Medicine Use Among Adults and Children: United States, 2007 by Patricia M. Barnes, M.A., and Barbara Bloom, M.P.A., Division of Health Interview Statistics, National Center for Health Statistics; and Richard L. Nahin, Ph.D., M.P.H., National Center for Complementary and Alternative Medicine, National Institutes of Health
(496) Chinese Herbal Bath Therapy for the Treatment of Knee Osteoarthritis: Meta-Analysis of Randomized Controlled Trials by Chen B1, Zhan H1, Chung M2, Lin X1, Zhang M1, Pang J1, Wang C3.(PubMed)

(497) Assessment of comparative pain relief and tolerability of SKI306X compared with celecoxib in patients with rheumatoid arthritis: a 6-week, multicenter, randomized, double-blind, double-dummy, phase III, noninferiority clinical trial by Song YW1, Lee EY, Koh EM, Cha HS, Yoo B, Lee CK, Baek HJ, Kim HA, Suh YI, Kang SW, Lee YJ, Jung HG.(PubMed)
(498) SKI306X inhibition of glycosaminoglycan degradation in human cartilage involves down-regulation of cytokine-induced catabolic genes by Choi CH1, Kim TH2, Sung YK2, Choi CB2, Na YI3, Yoo H4, Jun JB2.(PubMed)
(499) Effects of SKI306X on arachidonate metabolism and other inflammatory mediators by Kim JH1, Ryu KH, Jung KW, Han CK, Kwak WJ, Cho YB.(PubMed)
(500) Effect of SKI 306X, a new herbal anti-arthritic agent, in patients with osteoarthritis of the knee: a double-blind placebo controlled study by Jung YB1, Roh KJ, Jung JA, Jung K, Yoo H, Cho YB, Kwak WJ, Kim DK, Kim KH, Han CK(PubMed)



(501) Du Huo Ji Sheng Tang(American Dragon)
(502) Duhuo Jisheng Tang for treating osteoarthritis of the knee: a prospective clinical observation by Jung-Nien Lai,1 Huey-Jeng Chen,2 Chao-Chung Chen,3 Jer-Huei Lin,4 Jing-Shiang Hwang,5 and Jung-Der Wang(PMC)
(503) Osteoarthritis and nutrition. From nutraceuticals to functional foods: a systematic review of the scientific evidence by Ameye LG1, Chee WS.(PubMed)
(504) Chinese herbal recipe versus diclofenac in symptomatic treatment of osteoarthritis of the knee: a randomized controlled trial [ISRCTN70292892] by Teekachunhatean S1, Kunanusorn P, Rojanasthien N, Sananpanich K, Pojchamarnwiputh S, Lhieochaiphunt S, Pruksakorn S.(PubMed)
(505) Chinese Herbal Formula Huo-Luo-Xiao-Ling Dan Protects against Bone Damage in Adjuvant Arthritis by Modulating the Mediators of Bone Remodeling by Siddaraju M. Nanjundaiah,1 David Y.-W. Lee,2 Brian M. Berman,3 and Kamal D. Moudgil(Hindawi Publishing Corporation)
(506) Dose Escalation Study Of Chinese Herbs In Osteoarthritis Of The Knee (TCM-OAK)(Clinical trial. Gov)
(507) Huo-Luo-Xiao-Ling (HLXL)-Dan, a Traditional Chinese Medicine, for patients with osteoarthritis of the knee: a multi-site, randomized, double-blind, placebo-controlled phase II clinical trial by Lao L1, Hochberg M2, Lee DY3, Gilpin AM4, Fong HH5, Langenberg P6, Chen K7, Li EK8, Tam LS9, Berman B10.(PubMed)
(508) Anti-hyperalgesic and anti-inflammatory effects of the modified Chinese herbal formula Huo Luo Xiao Ling Dan (HLXL) in rats by Lao L1, Fan AY, Zhang RX, Zhou A, Ma ZZ, Lee DY, Ren K, Berman B.(PubMed)
(509) Experimental Study on Anti-Inflammatory Effect and Analgesic Effect of Simiao Powder by Jing Yun, Li weilin
(510) Randomized and controlled clinical study of modified prescriptions of Simiao Pill in the treatment of acute gouty arthritis by Shi XD1, Li GC, Qian ZX, Jin ZQ, Song Y.(PubMed)
(511) [Effects and mechanisms of Simiao pill on adjuvant arthritis rats model].[Article in Chinese]by Wang X1, Zhang X, Zhang L, Li Y.(PubMed)
(512) Treatment with SiMiaoFang, an anti-arthritis chinese herbal formula, inhibits cartilage matrix degradation in osteoarthritis rat model by Xu Y1, Liu Q, Liu ZL, Lim L, Chen WH, Lin N.(PubMed)
(513) Osteoporosis & Osteoarthritis in TCM Therapy by Chun Yi, Lu O.M.D., LAc.
(514) Anti-hypersensitivity effects of Shu-jing-huo-xue-tang, a Chinese herbal medicine, in CCI-neuropathic rats by Shu H1, Arita H, Hayashida M, Zhang L, An K, Huang W, Hanaoka K.(PubMed)
(515) Study of sokei-kakketu-to (shu-jing-huo-xue-tang) in adjuvant arthritis rats by Kanai S1, Taniguchi N, Higashino H.(PubMed)

The Delicious Smoothie of Green Tea, Pomegranates and Blueberry for Reduced Risk and Treatment of Genital herpes

Kyle J. Norton(Scholar, Master of Nutrients), all right reserved.
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

The smoothie for reduced risk and treatment of Genital herpes

Yield: 2 serving (about 8 ounce each)
1/2 cup cooked fennel
1 large slice of ginger
1/4 cup of celery
1 1/2 cups of almond milk

1. Place all ingredients in a blender and puree about 1 minute
2. Blend on high speed about 1 minute or until the mixture is thick and the ice is well crushed.
3. Serve immediately

The finding of a natural source for reduced risk and treatment of genital herpes  has encountered many obstacles, many ingredients showed initially the promising result in animal studies have not produced same potentials in either large sample size and mutli centers human trials.
Recent study from some well known institutions suggested that combination of green tea(1) and fennel(4) and celery(8) may hold a key for a natural ingredients for reduced painful symptoms and treatment of genital herpes.

Genital herpes is defined as an sexual transmitted infectious disease caused by the herpes simplex virus (HSV). People with multiple partners are at higher risk to develop the disease with no symptoms or symptoms of sores or lesions on the penis or outside the vagina, etc.

Green tea has been a precious drink in traditional Chinese culture and used exceptional in socialization for more than 4000 thousand years. Due to its commercial values and health effects, green tea now has been cultivated all over the world in suitable climate. According to the joint study lead by the Seton Hall University, green tea theaflavin polyphenols, inhibited >99% of the production of HSV-1 viral particles by protecing the cell before being infected by the virus(1).

Epigallocatechin gallate (EGCG), another green tea phytochemical, reduced the number of plaques in HIV-infected cultured cells and its modified EGCG, palmitoyl-EGCG, exhibited strong blocking of the production of infectious HSV-1 particle(2).

Dr. Isaacs CE and colleagues at the Institute for Basic Research in Developmental Disabilities, epigallocatechin gallate EGCG stabilized the pH range found in the vagina and exhibited a strongly promising potential  for use in a microbicide to reduce HSV transmission(3).

Pomegranates is a fruit-bearing small tree, genus Punica, belonging to family Lythraceae, native to Iran, cultivated in Asian since ancient time. Its ellagitannins, a diverse class of hydrolyzable tannins inhibited against ACV-resistant HSV-1 and 2, without showing toxicity(4).

In 3- dimensional analysis, combination of ellagitannins with acyclovir expressed markedly synergistic effects against HSV-1 and 2(5).
Other hydrolyzable tannins including chebulagic acid (CHLA) and punicalagin (PUG) showed inhibited effects against HSV as a competitors for glycosaminoglycans in the management and treament of HSV-1 infections(6).

Resveratrol is a phytochemical in the class of Stilbenoids, found abundantly in grape and blueberry. According to the Creighton University,natural polyphenols, esveratrol may process the potential to prevent sexually transmitted infections caused by HSV (herpes simplex virus)7).
According to Dr. Faith SA and colleagues, resveratrol inhibited herpes simplex virus (HSV) by significantly blocking HSV DNA synthesis, suppressing HSV induced activation of NF-kappaB, the pro inflammatory signaling pathway and impairing expression of HSV genes and synthesis of viral DNA(8),

The Smoothie of Green Tea, Pomegranates and Blueberry may hold a key for further studies in production of a curable natural remedy for prevention and treatment of  Genital herpes HSV.
.
People who are at  increased risk of Genital herpes HSV  due to family history, weaken immunity,....should drink at least one cup or more daily. People with Genital herpes HSV may drink as much as they can, depending to the digestive toleration.

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References

(1) Antiviral activity of theaflavin digallate against herpes simplex virus type 1 by de Oliveira A1, Prince D1, Lo CY2, Lee LH3, Chu TC4.(PubMed)

(2) Inhibition of herpes simplex virus type 1 with the modified green tea polyphenol palmitoyl-epigallocatechin gallate by de Oliveira A1, Adams SD, Lee LH, Murray SR, Hsu SD, Hammond JR, Dickinson D, Chen P, Chu TC.(PubMed)

(3) Epigallocatechin gallate inactivates clinical isolates of herpes simplex virus by Isaacs CE1, Wen GY, Xu W, Jia JH, Rohan L, Corbo C, Di Maggio V, Jenkins EC Jr, Hillier S.(PubMed)
(4) Ellagitannins as synergists of ACV on the replication of ACV-resistant strains of HSV 1 and 2. by Vilhelmova-Ilieva N1, Jacquet R2, Quideau S2, Galabov AS3.(PubMed)
(5) Three-dimensional analysis of combination effect of ellagitannins and acyclovir on herpes simplex virus types 1 and 2 by Vilhelmova N1, Jacquet R, Quideau S, Stoyanova A, Galabov AS.(PubMed)
(6) Hydrolyzable tannins (chebulagic acid and punicalagin) target viral glycoprotein-glycosaminoglycan interactions to inhibit herpes simplex virus 1 entry and cell-to-cell spread by Lin LT1, Chen TY, Chung CY, Noyce RS, Grindley TB, McCormick C, Lin TC, Wang GH, Lin CC, Richardson CD.(PubMed)
(7) Natural polyphenols: potential in the prevention of sexually transmitted viral infections by Date AA1, Destache CJ2.(PubMed)
(8) Resveratrol suppresses nuclear factor-kappaB in herpes simplex virus infected cells by Faith SA1, Sweet TJ, Bailey E, Booth T, Docherty JJ.(PubMed)