Medical Advisor Journals

Friday, May 20, 2016

The Smoothie of Green Tea and Low Fat Milk for Prevention and Treatment of Focal proliferative nephritis

Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years

Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

Imaging of long term intake of delicious smoothies loved by many with the power of reduced risk and treatment of chronic illness with no one mentions about. In fact, it happens. Epidemiological studies with strong evidences suggested that blueberry oral administration hold a potential with therapeutic values for reduced risk of women who carry the mutation gene and treatment of breast cancer(*).

The curable smoothies are collection of recipes produced from natural sources, including organic fruits and vegetables, and some herbs which have been proven effectively for reduced risk and treatment for diseases and syndromes by scientific research of clinical trials and/or studies.

The finding of foods from natural sources has been a dream of scientists and scholars since ancient time. Socrates Said," Let foods be your medicine and let medicine be your foods". Let all of us all exercise the values of the past wisdom to build a letter living and living health while enjoining these delicious drinks.

The smoothie for Prevention and treatment of Polyuria

Yield: 2 servings (about 8 ounces each)
1 cup low fat milk
1 cup green tea drink (Make from 4 grams of green tea, a slice of ginger and a cup of hot water lipped for 5 minutes, and let cool to room temperature)

1. Place all ingredients in a blender and puree about 1 minute
2. Blend on high speed about 1 minute or until the mixture is thick and the ice is well crushed. Add more green tea drink if needed
3. Serve immediately
Recent studies by some renowned institutions suggested that green tea(1) and low fat milk may be the next generation of ingredient extracted from natural sources for reduced risk and treatment of Focal proliferative nephritis.

Focal proliferative nephritis is a type of glomerulonephritis seen in 20% to 35% of causes of lupus nephritis.

Green tea has been a precious drink in traditional Chinese culture and used exceptional in socialization for more than 4000 thousand years. Due to its commercial values and health effects, green tea now has been cultivated all over the world in suitable climate. Its phytochemical (-)-epigallocatechin gallate (EGCG), exhibited prophylactic effects in enhancing the Nrf2 in regulation of antioefxidant signaling pathway and decreasing renal NLRP3 in activation of pro inflammatory pathways(1).

Cholecalciferol (vitamin D3) found abundantly in low fat milk may also benefit patients of g glomerulonephritis induced by systemic lupus(SLE). According to the Universidade Federal de São Paulo-Escola Paulista de Medicina, vitamin D analogs modulated the immune system in prevention of autoimmune diseases in induced kidney inflammation(2).

It is said that vitamin D also involved in the attenuated physiopathology of bone metabolism disturbance in patients with lupus nephritis.

The effectiveness of Green Tea and Low Fat Milk may serve as cornerstones of pharmaceutical target for further studies in production of a potential medication for prevention and treatment of Focal proliferative nephritis with little or no adverse effects.

People who are at high risk of Focal proliferative nephritis due to systemic lupus(SLE) and people with Focal proliferative nephritis should drink no more than 4 servings daily, depending to digestive toleration.

Life style and diet pattern change are necessary.

All Forms of Arthritis are Curable

You Can Eliminate Osteoarthritis

By addressing the Underlying Causes through Clinical Trials and Studies

Ovarian Cysts And PCOS Elimination

Holistic System In Existence That Will Show You How To

Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Super foods Library, Eat Yourself Healthy With The Best of the Best Nature Has to Offer

Reference(1) Epigallocatechin-3-gallate prevents lupus nephritis development in mice via enhancing the Nrf2 antioxidant pathway and inhibiting NLRP3 inflammasome activation by Tsai PY1, Ka SM, Chang JM, Chen HC, Shui HA, Li CY, Hua KF, Chang WL, Huang JJ, Yang SS, Chen A.(PubMed)
(2) [Immune modulation by vitamin D analogs in the prevention of autoimmune diseases].[Article in Dutch] by Bouillon R1, Verstuyf A, Branisteanu D, Waer M, Mathieu C.(PubMed)
(3) Bone disease in newly diagnosed lupus nephritis patients by Resende AL1, dos Reis LM1, Dias CB1, Custódio MR1, Jorgetti V1, Woronik V1.(PubMed)

Most Common Diseases of 50plus: Diabetes(The Articles) --- Pancreas and Type II Diabetes

If you are diabetic, the chance that you are overweight and this increase the
chance of high cholesterol and high blood pressure. So, to control the
glucose in your blood stream, you might want to try high protein diet
together with fighting cholesterol and high blood pressure natural remedies.

Diabetes is defined as a condition caused by insufficient insulin entering the bloodstream to regulate the glucose. It is either caused by cells in pancreas dying off or receptor sites clogged up by fat and cholesterol. In some cases, diabetes is also caused by allergic reactions of cells in the immune system.

Traditionally, diabetes is viewed as a failure of the pancreas to release
enough insulin for sugar metabolism. People with diabetes has grown
increasingly worse over last 10 years. The escalation in diabetes corresponds
to rise in heart disease, because of over weight, poor diet and lack of
exercise.
Before discussing the subject of what causes type II diabetes, you might want to know how does the pancreas help to maintain sugar in the blood stream.

The pancreas is located deep in the abdomen behind the stomach. It contains thin tubes joining to form a single opening into the intestine that is located just beyond the stomach.
The pancreas produces juices, enzymes and insulin.
1.The enzymes digest fat, protein, and
carbohydrates.

2. Pancreatic juices combined with juices from the intestines help to do the job of breaking down protein, carbohydrates and fat therefore it plays an important role in maintaining good health.

3.The pancreas also produces insulin, which is important in regulating the amount of sugar or glucose in the blood.

There are 3 different kinds of type II diabetes

1. If some of the cells in the pancreas die off the pancreas can't produce enough insulin to regulate sugar in the blood stream, then we have type II diabetes that are caused by deficiency of insulin.
Today experts still don't know the causes of how pancreas cells die off, but they suspect that excessive alcohol drinking may be the factor. According to surveys, 70% of patients with type II insulin deficiency diabetes were heavy alcohol users.

2.If the pancreas produces enough insulin, but the receptor sites are clogged up by fat and cholesterol causing insulin not being pick up at the cell from receptor sites, we have type II insulin sufficient diabetes.
Most cases of type II insulin sufficient diabetes are caused by uncontrolled diet that are high in saturated fat, smoking and excessive alcohol drinking.

3. If the pancreas also produces enough insulin, but allergic responses to certain foods cause resistance of cells to allow insulin to enter blood stream. In other words, if the cells of the muscle and liver resist to take up glucose from the blood causing high concentration of glucose in the blood stream, we have a case of type II insulin resistance diabetes. The foods creating this problem vary from person to person. Most people with type II insulin resistance diabetes seem to be precipitated by overweight, smoking and excessive alcohol drinking. Type II insulin resistant diabetics should have allergy shots in order to find the exact foods causing insulin resistance reactions.
All Forms of Arthritis are Curable
You Can Eliminate Osteoarthritis
By addressing the Underlying Causes through Clinical Trials and Studies

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to General health http://kylejnorton.blogspot.ca/p/general-health.html

Back to Kyle J. Norton Home page http://kylejnorton.blogspot.ca

Food Therapy: Garbanzo beans (chickpeas, Cicer)

Kyle J. Norton(Scholar and Master of Nutrients, all right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

Garbanzo beans also known as chickpea is an edible legume of genus Cicer and the family Fabaceae, high in protein and minerals. It is one of the earliest cultivated vegetables, native to Middle East.

Nutrients
1. Carbohydrates
2. Dietary fiber
3. Fat
4. Protein
5. Vitamin A
6. Thiamine (Vitamin B1)
7. Riboflavin (Vitamin B2)
8. Niacin (Vitamin B3)
9. Pantothenic acid (B5)
10. Vitamin B6
11. Folate (Vitamin B9)
12. Vitamin C
13. Vitamin E
14. Vitamin K
15. Iron
16. Magnesium
17. Phosphorus
18. Potassium
19. Zinc
20. Etc.

Health benefits
A. Health benefits according to studies
1. Antioxidants
In the observation of chemical compound Phenol of chickpeas (Cicer arietinum L.) and its antioxidant capacity found that the levels of antioxidant capacity were in accordance with the behavior of phenolic compounds exhibiting noticeable reductions in Castellano chickpea and not relevant changes in Sinaloa chickpea. Thus, the significant occurrence of bioactive phenolic compounds along with the relevant antioxidant capacities of dehydrated chickpea flours make them to be considered functional ingredients for their beneficial health effects, especially in case of Sinaloa, according to "Phenolic profile and antioxidant capacity of chickpeas (Cicer arietinum L.) as affected by a dehydration process" by Aguilera Y, Dueñas M, Estrella I, Hernández T, Benitez V, Esteban RM, Martín-Cabrejas MA.(a)

2. Free radicals scavenging activity
In the assessment of pectin (CAP) was extracted from the husk of Cicer arietinum L anmd its antioxidant effect found that at 1.0 mg/mL CAP exhibited a scavenging rate of 29% on DPPH radicals. The evaluation of antioxidant activity suggested that CAP had good potential for DPPH radical scavenging activity and should be explored as a novel potential antioxidant, according to "Component analysis and free radicals scavenging activity of Cicer arietinum L. husk pectin" by Urias-Orona V, Huerta-Oros J, Carvajal-Millán E, Lizardi-Mendoza J, Rascón-Chu A, Gardea AA.(b)

3. Antifungal activity
In the investigation of Melia azedarach L. leaves and it effects against Ascochyta rabiei (Pass.) found that the tested compounds exhibited variable antifungal activity against the target fungal pathogens. All compounds showed their highest antifungal activity after 24 h of incubation. Compound 2 was found to be the most effective, with an MIC of 0.0156 mg mL(-1), followed by compounds 3, 4 and 5, with MIC values of 0.0312, 0.25 and 0.125 mg mL(-1), respectively, accoridng to "Antifungal compounds from Melia azedarach leaves for management of Ascochyta rabiei, the cause of chickpea blight" by Jabeen K, Javaid A, Ahmad E, Athar M.(c)

4. Bowel health
In the examination of both changes in food consumption, satiation and perceived bowel health while consuming a diet rich in chickpeas, found that perceived satiation increased while participants consumed chickpeas and perceived bowel function improved. Health benefits, increases in dietary variety and satiation with legume consumption were the main perceived benefits, while inconvenience and gastrointestinal upset discouraged legume consumption, according to "Chickpea supplementation in an Australian diet affects food choice, satiety and bowel health" by Murty CM, Pittaway JK, Ball MJ.(d)

5. Etc.

B. Health benefits according to concentration
1. Molybdenum
Molybdenum cofactor is vital for human enzymes, including xanthine oxidase, sulfite oxidase, and aldehyde oxidase, Deficiency may cause
a. Prenatal brain disruption, according to the study of "Prenatal brain disruption in molybdenum cofactor deficiency" by Carmi-Nawi N, Malinger G, Mandel H, Ichida K, Lerman-Sagie T, Lev D.(1)
b. Uniparental isodisomy with microcephaly and developmental delay, according to the study of "Maternal uniparental isodisomy is responsible for serious molybdenum cofactor deficiency" by Gümüş H, Ghesquiere S, Per H, Kondolot M, Ichida K, Poyrazoğlu G, Kumandaş S, Engelen J, Dundar M, Cağlayan AO.(2)

2. Manganese
It is one of important trace in preventing osteoporosis, according to the study of "[Study of estrogen deficiency impact on manganese levels in teeth and mandible of rats after ovariectomy]. [Article in Polish]" by Rahnama M, Błoniarz J, Zareba S, Swiatkowski W.(1)and regulating blood sugar level, according to the study of "[An inadequate intake of manganese may favour insulin resistance in girls]. [Article in Spanish]" by Rodríguez-Rodríguez E, Bermejo LM, López-Sobaler AM, Ortega RM.(3)

3. Dietary Fibers

Daily intake of right amount of fibers can prvent and treata. Diabetes, as Increased consumption of vegetables, whole grains, and soluble and insoluble fiber is associated with improved glucose metabolism in both diabetic and nondiabetic individuals. Improvements in insulin sensitivity and glucose homeostasis were more evident in participants following a plant-based diet compared with other commonly used diets, according to the study of "Efficacy of high-fiber diets in the management of type 2 diabetes mellitus" by Wolfram T, Ismail-Beigi F.(4)

4. Folate
In the investigation of the prevalence and multifactorial etiology of anemia among Indian human immunodeficiency virus (HIV)-infected children and its effect onanemia, found that Anemia, particularly iron deficiency anemia and anemia of inflammation, is highly prevalent among children with HIV infection. Micronutrient supplements (iron and, folate) combined with ART(antiretroviral therapy) improved anemia in HIV-infected children, according to "The prevalence and etiology of anemia among HIV-infected children in India" by Shet A, Arumugam K, Rajagopalan N, Dinakar C, Krishnamurthy S, Mehta S, Shet AS.(5)

5. Etc.

C. Other health benefits
1. Cardiovascular disease
Since garbanzo bean contains measure amount of soluble and insoluble dietary fibers, it helps to improve the digestive track in expelling bad cholesterol through waste removal by binding with them, thus reducing the risk of of heart diseases. In a study of "Effects of soluble dietary fiber on low-density lipoprotein cholesterol and coronary heart disease risk" by Bazzano LA., posted in PubMed (http://www.ncbi.nlm.nih.gov/pubmed/18937894), researchers indicated that Strong epidemiologic and experimental data suggest that increasing dietary fiber may help to lower low-density lipoprotein cholesterol (LDL-C) and decrease the risk of coronary heart disease. Recent studies have highlighted the role of dietary fiber, particularly water-soluble varieties, in decreasing the risk of cardiovascular disease.

2. Constipation
While soluble fiber can dissolve easily in water and takes on a soft, gel-like texture in the intestines, insoluble fiber passes through the intestines almost undigested. Together, they prevent the forming of hard, dry stools that are difficult to pass., according to the study of "A controlled, randomized, double-blind trial to evaluate the effect of a supplement of cocoa husk that is rich in dietary fiber on colonic transit in constipated pediatric patients" by Castillejo G, Bulló M, Anguera A, Escribano J, Salas-Salvadó J.

3. Blood sugar
High amount of fiber not only makes the stomach feeling fullness, but also releases the glucose slowly into the bloodstream, thus reducing the risk of insulin sensitive and benefiting people who suffer from insulin-resistance diabetes or hypoglycemia., according to the study of "Effect of dietary fiber on complications of gastric surgery: prevention of postprandial hypoglycemia by pectin" by Jenkins DJ, Gassull MA, Leeds AR, Metz G, Dilawari JB, Slavin B, Blendis LM., posted in PubMed (http://www.ncbi.nlm.nih.gov/pubmed/873118)

4. Nervous system
Protein in garbanzo bean is essential for nervous system in information transmitting between cells and cells in other parts of the body, thus reducing the risk of nervous tension cause of mood change, stress, anxiety, etc., according to the study of "The planar polarity protein Scribble1 is essential for neuronal plasticity and brainfunction" by Moreau MM, Piguel N, Papouin T, Koehl M, Durand CM, Rubio ME, Loll F, Richard EM, Mazzocco C, Racca C, Oliet SH, Abrous DN, Montcouquiol M, Sans N, posted in PubMed (http://www.ncbi.nlm.nih.gov/pubmed/20660256)

5. Iron
Garbanzos are very important for menstruating women, as they help them replenishing any kind of iron deficiency in the body. Iron is especially beneficial for women who are either pregnant or lactating, according to the study of "[Irondeficiency and overload. Implications in oxidative stress and cardiovascular health].[Article in Spanish]" by Toxqui L, De Piero A, Courtois V, Bastida S, Sánchez-Muniz FJ, Vaquero MP., posted in PubMed, (http://www.ncbi.nlm.nih.gov/pubmed/20593115) it also helps in production of red blood cells and formation of hemoglobin which enhances the absorption oxygen from the lung to nourish the cells in the body.

6. Manganese
Manganese beside is a mineral essential for energy production and metabolism of foods, it also helps to improve immune-system functioning that reduces the risk of inflammation, according to the study of "The effects of 3, 4 or 5 amino salicylic acids on manganese-induced neuronal death: ER stress and mitochondrial complexes" by Yoon H, Lee GH, Kim DS, Kim KW, Kim HR, Chae HJ., posted in PubMed (http://www.ncbi.nlm.nih.gov/pubmed/21477646 researchers indicated that the salicylate analogues and the antioxidants did not mediate ER stress in this model. The salicylate analogues reduced reactive oxygen species (ROS) and reversed the deficient mitochondrial membrane potential that was induced by Mn. Taken together, the 3, 4, 5 ASA worked in a similar way, regulating the Mn-induced mitochondrial dysfunction and protecting cells.

6. Etc.

Side effect
1. Purines
Garbanzo bean contains measure amount of purines, excessive intake of purines can cause gout and formation of kidney stones.
2. Sulphites
Sulphites in garbanzo bean can cause symptoms of rapid heartbeat, headache and disorientation for certain people.
3. Etc.

All Forms of Arthritis are Curable
You Can Eliminate Osteoarthritis
By addressing the Underlying Causes through Clinical Trials and Studies

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Super foods Library, Eat Yourself Healthy With The Best of the Best Nature Has to Offer

Sources
(a) http://www.ncbi.nlm.nih.gov/pubmed/21573982
(b) http://www.ncbi.nlm.nih.gov/pubmed/20938405
(c) http://www.tandfonline.com/doi/abs/10.1080/14786411003754298
(d) http://www.ncbi.nlm.nih.gov/pubmed/19945492
(1) http://www.ncbi.nlm.nih.gov/pubmed/21285035
(2) http://onlinelibrary.wiley.com/doi/10.1111/j.1469-8749.2010.03724.x/pdf
(3) http://www.ncbi.nlm.nih.gov/pubmed/22072339
(4) http://www.ncbi.nlm.nih.gov/pubmed/20713332
(5) http://www.ncbi.nlm.nih.gov/pubmed/22009132

Herbal therapy: Popular Herbal Chaste tree berry (Vitex agnus-castus)

Phytochemicals In Foods: The effects of Anacardic acid

Anacardic acid are phytichemicals of the organic acid found abundantly in cashews, mangoes, etc.

The effects of Anacardic acid include
1. Breast cancer
In the investigation of Anacardic acid (AnAc; 2-hydroxy-6-alkylbenzoic acid), a dietary and medicinal phytochemical with established anticancer activity, found that AnAc inhibits cancer cell proliferation remain undefined. AnAc 24:1(omega5) was purified from geranium (Pelargonium x hortorum) and shown to inhibit the proliferation of estrogen receptor alpha (ERalpha)-positive MCF-7 and endocrine-resistant LCC9 and LY2 breast cancer cells with greater efficacy than ERalpha-negative primary human breast epithelial cells, according to "Anacardic acidinhibits estrogen receptor alpha-DNA binding and reduces target gene transcription and breast cancer cell proliferation" by Schultz DJ, Wickramasinghe NS, Ivanova MM, Isaacs SM, Dougherty SM, Imbert-Fernandez Y, Cunningham AR, Chen C, Klinge CM.(1)

2. Anti Cancer and inflammatory effects
In the optimization of histone acetyltransferases (HATs), a novel drug targets for treatment of diseases like, for example, cancer and inflammation, showed that in derivatives synthesized using a novel synthetic route, one compound showed a twofold improved inhibitory potency for the PCAF HAT activity and a twofold improved inhibition of histone acetylation in HEP G2 cells, according to " Improved inhibition of the histone acetyltransferase PCAF by an anacardic acidderivative" by Ghizzoni M, Boltjes A, Graaf C, Haisma HJ, Dekker FJ.(2)

3. Prostate cancer
In the postulation of that anacardic acid affects multiple steps of tumor angiogenesis to contribute to tumor inhibition, showed that when anacardic acid (2 mg/kg per day) was subcutaneously administrated to mice bearing human prostate tumor xenografts (n = 6-7), the volume and weight of solid tumors were significantly retarded. Src, Ki-67, and CD31 immunohistochemical staining further revealed that Src protein expression, tumor cell proliferation, and microvessel density could be remarkably suppressed by anacardic acid. Taken together, according to "Anacardic acid (6-pentadecylsalicylic acid) inhibits tumor angiogenesis by targeting Src/FAK/Rho GTPases signaling pathway" by Wu Y, He L, Zhang L, Chen J, Yi Z, Zhang J, Liu M, Pang X.(3)

4. Antimicrobial activity
In the investigation of a new anacardic acid, 6-[16'Z-nonadecenyl]-salicylic acid (1), along with seven known compounds, 6-[8'Z-pentadecenyl] salicylic acid (15:1anacardic acid) (2), 6-nonadecenyl salicylic acid (anacardic acid 19:0) (3), 6-pentadecyl salicylic acid (anacardic acid 15:0) (4), masticadienonic acid (5), 3α-hydroxymasticadienonic acid (6), 3-epi-oleanolic acid (7) and β-sitosterol, isolated from the bark of Amphipterygium adstringens, showed that compounds 1-4 exhibited antibacterial activity against Streptococcus mutans and Porphyromonas gingivalis with minimum inhibitory concentrations ranging from 7 to 104 µg mL and from 12 to 126 µg mL, respectively, according to "Isolation of the new anacardic acid 6-[16'Z-nonadecenyl]-salicylic acid and evaluation of its antimicrobial activity against Streptococcus mutans and Porphyromonas gingivalis" by Rivero-Cruz BE, Esturau N, Sánchez-Nieto S, Romero I, Castillo-Juárez I, Rivero-Cruz JF.(4)

5. Cell proliferation
In the evaluation of the role of lunasin, alone and in combination with aspirin andanacardic acid on cell proliferation and foci formation of transformed NIH/3T3 cells induced by chemical carcinogens 7,12-dimethylbenz[a]anthracene or 3-methylcholanthrene, found that lunasin, acting as a single agent, inhibits cell proliferation and foci formation. When combined with aspirin, these effects were significantly increased, indicating that this combination might be a promising strategy to prevent/treat cancer induced by chemical carcinogens, according to "Lunasin-aspirin combination against NIH/3T3 cells transformation induced by chemical carcinogens" by Hsieh CC, Hernández-Ledesma B, de Lumen BO.(5)

6. Pituitary tumors
In the investigation of the effect of anacardic acid (6-pentadecyl salicylic acid), a natural histone acetyltransferase inhibitor, on pituitary adenoma cells, showed thatAnacardic acid reduced the expression of survivin and X-linked inhibitor of apoptosis protein, antiapoptotic proteins associated with cellular survival and radioresistance, and radiosensitized pituitary adenoma cells, according to "Anacardic acid induces caspase-independent apoptosis and radiosensitizes pituitary adenoma cells" by Sukumari-Ramesh S, Singh N, Jensen MA, Dhandapani KM, Vender JR.(6)

7. Antioxidant, larvicidal and antiacetylcholinesterase activities
In the evaluation of Anacardic acid, cardanol and cardol, the main constituents of natural cashew nut shell liquid (CNSL), were obtained by solvent extraction and assayed for antioxidant, larvicidal and antiacetylcholinesterase activity, showed that cardanol as the most active, followed by cardol and anacardic acid. The three CNSL components demonstrated good larvicidal activity against Aedes aegypti (LC(50)=12.40 for anacardic acid, 10.22 for cardol and 14.45 for cardanol) and exhibited inhibition zones for acetylcholinesterase enzymes in the TLC test similar to carbachol, which was used as standard, according to "Antioxidant, larvicidal and antiacetylcholinesterase activities of cashew nut shell liquid constituents" by Oliveira MS, Morais SM, Magalhães DV, Batista WP, Vieira IG, Craveiro AA, de Manezes JE, Carvalho AF, de Lima GP.(7)

8. Etc.

References
(1) http://www.ncbi.nlm.nih.gov/pubmed/20197399
(2) http://www.ncbi.nlm.nih.gov/pubmed/20655754
(3) http://www.ncbi.nlm.nih.gov/pubmed/21828260
(4) http://www.ncbi.nlm.nih.gov/pubmed/21815722
(5) http://www.ncbi.nlm.nih.gov/pubmed/21562729
(6) http://www.ncbi.nlm.nih.gov/pubmed/21275565
(7) http://www.ncbi.nlm.nih.gov/pubmed/20707981

Most Common Disease of 50plus: The Clinical trials and Studies of Musculo-Skeletal disorders(MSDs) - Rheumatoid Arthritis: Herbal formula Keishibukuryogan

Kyle J. Norton (Scholar)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

Musculoskeletal disorders (MSDs) are medical condition mostly caused by work related occupations and working environment, affecting patients’ muscles, joints, tendons, ligaments and nerves and developing over time. A community sample of 73 females and 32 males aged 85 and over underwent a standardised examination at home. Musculoskeletal pain was reported by 57% of those interviewed. A major restriction of joint movement range was frequent in the shoulder but uncommon in other joints(1).

Types of Musculo-Skeletal disorders in elder(2)
1. Osteoarthritis
2. Gout
3. Rheumatoid Arthritis
4. Polymalagia Arthritis
5. Cervical myleopathy and spinal canal stenosis
6. Osteoporosis
7. Low back pain
8. Fibromyalgia

Rheumatoid Arthritis

Rheumatoid Arthritis is defined a chronic disorder as a result of inflammation, affecting mostly the flexible (synovial) joints and tissues and organs in the body. The disease affects more women than men and generally occurs after the ages of 40, causing diminished quality of life of many elders(1). According to CDC, Musculoskeletal disorders (MSDs) affects over 52 millions of adults in the US alone, including 294,000 children under age 18 with some form of arthritis or rheumatic conditions(2). Rheumatoid Arthritis can induced bone loss through elevating bone resorption without increasing bone formation(4). A cross-sectional population-based study of 1042 patients with rheumatoid arthritis showed that RA patients had an increased risk of death from various causes(4a).

The Treatment

B. Treatment in herbal and traditional Chinese medicine
B.9. The herbal formulas in herbal and traditional Chinese medicine
Rheumatoid arthritis (RA) is a common worldwide public health problem especially in China, many RA formula has been used in the clinic and some of these TCM formulas have been existed over thousands of years in ancient China(388) with potential mechanisms such as inhibited osteoclast proliferation, suppressed fibroblast, decreased the expression of inflammatory cytokines, blocking signal pathways, etc.).
2. Keishibukuryogan
Keishibukuryogan, is a formul for the improvement of blood circulation may be a potential herbal formula used a treatment for reduced symptoms of RA, through its antioxidant and anti inflammatory effects on vascular function(389). As one of the most frequently used Kampo medicines in Japan, the herbal formula also has been used as biomarker protein (haptoglobin alpha 1 chain) for discriminating responders from non-responders in applying KBG for treatment of RA's patient(390).
Furthermore, application of Keishibukuryogan has shown to decreased tender joint count, swollen joint count and DAS(28) decreased significantly with CRP and inflammatory cytokines remained unchanged(391) in RA 's patient.

All Forms of Arthritis are Curable
You Can Eliminate Osteoarthritis
By addressing the Underlying Causes through Clinical Trials and Studies

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to General health http://kylejnorton.blogspot.ca/p/general-health.html

Back to Kyle J. Norton Home page http://kylejnorton.blogspot.ca

References
(1) 8 Areas of Age-Related Change(NIH)
(2) Arthritis-Related Statistics(CDC)
(3) Valgus deformities of the feet and characteristics of gait in patients who have rheumatoid arthritis by Keenan MA1, Peabody TD, Gronley JK, Perry J.(PubMed)
(4) Serum Sclerostin Level Among Egyptian Rheumatoid Arthritis Patients: Relation to Disease Activity ,Bone Mineral Density and Radiological Grading by Mehaney DA, Eissa M, Anwar S, El-Din SF(PubMed)
(4a) Death rates and causes of death in patients with rheumatoid arthritis: a population-based study by Sihvonen S1, Korpela M, Laippala P, Mustonen J, Pasternack A(PubMed)
(388) The treatment of rheumatoid arthritis using Chinese Medicinal Plants: From pharmacology to potential molecular mechanisms by Lü S1, Wang Q2, Li G3, Sun S4, Guo Y4, Kuang H5.(PubMed)
(389) Effects of keishibukuryogan on vascular function in adjuvant-induced arthritis rats by Nozaki K1, Goto H, Nakagawa T, Hikiami H, Koizumi K, Shibahara N, Shimada Y.(PubMed)
(390) Identification of a predictive biomarker for the beneficial effect of a Kampo (Japanese traditional) medicinekeishibukuryogan in rheumatoid arthritis patients by Ogawa K1, Kojima T, Matsumoto C, Kamegai S, Oyama T, Shibagaki Y, Muramoto H, Kawasaki T, Fujinaga H, Takahashi K, Hikiami H, Goto H, Kiga C, Koizumi K, Sakurai H, Shimada Y, Yamamoto M, Terasawa K, Takeda S, Saiki I.(PubMed)
(391) Keishibukuryogan (gui-zhi-fu-ling-wan), a Kampo formula, decreases disease activity and soluble vascular adhesion molecule-1 in patients with rheumatoid arthritis by Nozaki K1, Hikiami H, Goto H, Nakagawa T, Shibahara N, Shimada Y.(PubMed)

The Smoothie of Green Tea, Grape and Curcumin for Prevention and Treatment of Vaginal Bleeding in Menopause caused by Cervicitis

Kyle J. Norton(Scholar, Master of Nutrients), all right reserved.
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
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Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

The finding of a natural source for reduced risk and treatment of Vaginal Bleeding in Menopause caused by Cervicitis has encountered many obstacles, many ingredients showed initially the promising result in animal studies have not produced same potentials in either large sample size and mutli centers human trials.

Scientists in some well known institutions may have found the therapeutic and potential ingredients from natural sources(Green tea and grape) for reduced risk and treatment of Vaginal Bleeding in Menopause caused by uterus or cervix infection.

Abnormal vaginal bleeding is a bleeding when you do not suppose to such as menopause, pregnancy or when your menstruation is lighter or heavier than it should be.

The smoothie for reduced risk and treatment of Vaginal Bleeding in Menopause caused by Cervicitis
Yield: 2 servings (about 8 ounces each)
1 1/2 cups grape
1 tsp curcumin
1 cup green tea drink (Make from 4 grams of green tea, a slice of ginger and a cup of hot water lipped for 5 minutes, and let cool to room temperature)

1. Place all ingredients in a blender and puree about 1 minute
2. Blend on high speed about 1 minute or until the mixture is thick and the ice is well crushed. Add more green tea drink if needed

3. Serve immediately

Cervicitis is an inflammation of the cervix.

Green tea has been a precious drink in traditional Chinese culture and used exceptional in socialization for more than 4000 thousand years. Due to its commercial values and health effects, green tea now has been cultivated all over the world in suitable climate.

According to the The Catholic University of Korea, green tea extracts (polyphenon E; poly E and (-)-epigallocatechin-3-gallate [EGCG]) exhibited anti human papilloma virus (HPV) infected cervical lesions at a a 200 mg of poly E taken orally every day for eight to 12 weeks(1).

The phytochemicals of epigallocatechin gallate and polyphenols E also inhibited immortalized HPV-immortalized cervical epithelial cells and cancer cell growth. induced apoptosis through cell cycle change, according Guangxi Medical University(2).

Turmeric is a perennial plant in the genus Curcuma, belonging to the family Zingiberaceae, native to tropical South Asia. Its phytochemical curcumin can stimulate prevention of multiple sexually transmitted infections of cervix caused by HIV (human immunodeficiency virus), HSV (herpes simplex virus) and HPV (human papilloma virus)(3).

According to the Air Force General Hospital of People's Liberation Army, curcumin induced apoptosis of HPV-positive human cervical cancer cells via the anti inflammatory/cellular tumor antigen NF-κB-p53-caspase-3 pathway(4).
In a phase II randomized controlled study,curcumin and curcumin containing polyherbal preparations have demonstrated anti-microbial and anti- viral properties against cervical human papillomavirus (HPV) infection(5).

Resveratrol is a phytochemical in the class of Stilbenoids, found abundantly in grape, etc. may also expressed immune modulating effects(6) against human papillomavirus (HPV)induced inflammation(7) and malignant progression in neoplasms(8).

The effectiveness of Green Tea, Curcumin and Grape may serve as cornerstones of pharmaceutical target for further studies in production of a potential medication for for Reduced Risk of Consequences of cervicitis with little or no adverse effects.

Women who are at increased risk of Cervicitis due to sexual active,.... should take 1 - 2 servings daily and women with Cervicitis should take as much as they can depending to the digestive toleration.
Life style and dietary patter change are recommended.

References

(1) Protective effects of green tea extracts (polyphenon E and EGCG) on human cervical lesions by Ahn WS1, Yoo J, Huh SW, Kim CK, Lee JM, Namkoong SE, Bae SM, Lee IP.(PubMed)

(2) Green tea compound in chemoprevention of cervical cancer by Zou C1, Liu H, Feugang JM, Hao Z, Chow HH, Garcia F.(PubMed)
(3) Natural polyphenols: potential in the prevention of sexually transmitted viral infections by Date AA1, Destache CJ2.(PubMed)
(4) Curcumin improves the paclitaxel-induced apoptosis of HPV-positive human cervical cancer cells via the NF-κB-p53-caspase-3 pathway by Dang YP1, Yuan XY1, Tian R1, Li DG1, Liu W1.(PubMed)
(5) Clearance of cervical human papillomavirus infection by topical application of curcumin andcurcumin containing polyherbal cream: a phase II randomized controlled study by Basu P1, Dutta S, Begum R, Mittal S, Dutta PD, Bharti AC, Panda CK, Biswas J, Dey B, Talwar GP, Das BC.(PubMed)
(6) The enhancement of immune function and activation of NF-κB by resveratrol-treatment in immunosuppressive mice by Lai X1, Pei Q2, Song X1, Zhou X1, Yin Z3, Jia R4, Zou Y1, Li L1, Yue G5, Liang X1, Yin L1, Lv C1, Jing B1(PubMed)
(7) Regulation of immune responses to HPV infection and during HPV-directed immunotherapy by Bhat P1, Mattarollo SR, Gosmann C, Frazer IH, Leggatt GR.(PubMed)
(8) The role of human papilloma virus (HPV) infection in non-anogenital cancer and the promise of immunotherapy: a review by Cobos C1, Figueroa JA, Mirandola L, Colombo M, Summers G, Figueroa A, Aulakh A, Konala V, Verma R, Riaz J, Wade R, Saadeh C,Rahman RL, Pandey A, Radhi S, Nguyen DD, Jenkins M, Chiriva-Internati M, Cobos E.(PubMed)