Thursday, June 2, 2016

Food therapy - Vegetables - Beet (Beta vulgaris)

Kyle J. Norton(Scholar and Master of Nutrients, all right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

                           Beet
Beet is best known as the beetroot or garden beet and belong to the amaranth family. It is a perennial plant with leafy stems growing to 1–2 m tall.

Nutrients
1. Energy
2. Carbohydrates
3. fiber
4. Protein
5. Vitamin A
6. Beta-carotene
7. Trytophan
8. Thiamine (Vitamin B1)
9. Riboflavin (Vitamin B2)
10. Niacin (Vitamin B3)
11. Pantothenic acid (Vitamin B5)
12. Vitamin B6
13. Folate (Vitamin B9)
14. Vitamin C
15. Calcium
16. Iron
17. Magnesium
18. Copper
19. Phosphorus
20. Potassium
21. Zinc
22. Magnesium
23. Betacyanin
24. Betaine
25. Etc.

Health benefits
A. Health benefits according to studies
1. Cell Apoptosis
In the assessment of the extract of red beetroot (Beta vulgaris L.) and its effect in suppressing the development of multi-organ tumors found that betanin, the majorbetacyanin constituent, may play an important role in the cytotoxicity exhibited by the red beetroot extract. Further studies are needed to evaluate the chemopreventive potentials of the beetroot extract when used alone or in combination with doxorubicin to mitigate the toxic side-effects of the latter, according to "Cytotoxic effect of the red beetroot (Beta vulgaris L.) extract compared to doxorubicin (Adriamycin) in the human prostate (PC-3) and breast (MCF-7) cancer cell lines" by Kapadia GJ, Azuine MA, Rao GS, Arai T, Iida A, Tokuda H.(a)

2. Antioxidants
In the assessment of betacyanins and betaxanthins found in cactus pear fruit ( Opuntia ficus indica L. Mill. cv. Gialla and Rossa) and red beet ( Beta vulgaris L. ssp. vulgaris) indicated that Betaxanthins were wholly soluble in the aqueous (bioaccessible) fraction after ultracentrifugation of the postintestinal (PI) digesta, whereas release of betacyanins from the matrix was incomplete. PI digesta inhibited dose-dependently the oxidation of methyl linoleate in methanol, an effect not correlated with the betalain content, according to "In vitro digestion of betalainic foods. Stability and bioaccessibility of betaxanthins and betacyanins and antioxidative potential of food digesta" by Tesoriere L, Fazzari M, Angileri F, Gentile C, Livrea MA.(b)

3. Cardiovascular diseases
In the classification of the effect of fruits and vegetables in blood pressure (BP) and the risk of adverse cardiovascular events found that approximately 3 hours after ingestion of a dietary nitrate load (beetroot juice 500 mL), BP was substantially reduced (Delta(max) -10.4/8 mm Hg); an effect that correlated with peak increases in plasma nitrite concentration. The dietary nitrate load also prevented endothelial dysfunction induced by an acute ischemic insult in the human forearm and significantly attenuated ex vivo platelet aggregation in response to collagen and ADP, according to "Acute blood pressure lowering, vasoprotective, and antiplatelet properties of dietary nitrate via bioconversion to nitrite" by Webb AJ, Patel N, Loukogeorgakis S, Okorie M, Aboud Z, Misra S, Rashid R, Miall P, Deanfield J, Benjamin N, MacAllister R, Hobbs AJ, Ahluwalia A.(c)

4. Lung and Skin Cancer
In the assessment of Beta vulgaris (beet) root extract and its effect on cancers found that in vivo anti-tumor promoting activity evaluation against the mice skin and lung bioassays also revealed a significant tumor inhibitory effect. The combined findings suggest that beetroot ingestion can be one of the useful means to prevent cancer, according to "Chemoprevention of lung and skin cancer byBeta vulgaris (beet) root extract" by Kapadia GJ, Tokuda H, Konoshima T, Nishino H.(d)

5. Etc.

B. Health benefits according to concentration
1. Folate
In the investigation of the prevalence and multifactorial etiology of anemia among Indian human immunodeficiency virus (HIV)-infected children and its effect onanemia, found that Anemia, particularly iron deficiency anemia and anemia of inflammation, is highly prevalent among children with HIV infection. Micronutrient supplements (iron and, folate) combined with ART(antiretroviral therapy) improved anemia in HIV-infected children, according to "The prevalence and etiology of anemia among HIV-infected children in India" by Shet A, Arumugam K, Rajagopalan N, Dinakar C, Krishnamurthy S, Mehta S, Shet AS.(1)

2. Manganese
It is one of important trace in preventing osteoporosis, according to the study of "[Study of estrogen deficiency impact on manganese levels in teeth and mandible of rats after ovariectomy]. [Article in Polish]" by Rahnama M, Błoniarz J, Zareba S, Swiatkowski W.(2)and regulating blood sugar level, according to the study of "[An inadequate intake of manganese may favour insulin resistance in girls]. [Article in Spanish]" by Rodríguez-Rodríguez E, Bermejo LM, López-Sobaler AM, Ortega RM.(3)

3. Dietary fiber
Daily intake of right amount of fibers can prvent and treata. Diabetes, as Increased consumption of vegetables, whole grains, and soluble and insoluble fiber is associated with improved glucose metabolism in both diabetic and nondiabetic individuals. Improvements in insulin sensitivity and glucose homeostasis were more evident in participants following a plant-based diet compared with other commonly used diets, according to the study of "Efficacy of high-fiber diets in the management of type 2 diabetes mellitus" by Wolfram T, Ismail-Beigi F.(4)

4. Potassium
Potassium beside is important in maintaining the regular contraction and relaxation of the muscle, that helps to reducing the risk of hypokalemia, it also helps the lymphatic system in regulating the levels of fluid in the body, thus lessening the risk of lymphedema, swelling caused by the accumulation of lymph fluid. In a study of "Narrative review: evolving concepts in potassium homeostasis andhypokalemia" by Greenlee M, Wingo CS, McDonough AA, Youn JH, Kone BC., posted in PubMed (http://www.ncbi.nlm.nih.gov/pubmed/19414841), researchers found that recent experimental insights into the participation of feedback and feedforward control mechanisms in potassium homeostasis. New data make clear that feedforward homeostatic responses activate when decreased potassiumintake is sensed, even when plasma potassium concentration is still within the normal range and before frank hypokalemia ensues, in addition to the classic feedback activation of renal potassium conservation when plasma potassiumconcentration decreases.

5. Vitamin C
In the evaluation of pulmonary dysfunction. and it effects on pulmonary dysfunction found that At present, evidence from randomised-controlled trials is insufficient to recommend a specific role for vitamin C in the treatment of asthma. Further methodologically strong and large-scale randomised controlled trials are needed in order to address the question of the effectiveness of vitamin C in children with asthma but some outcome data showed effectiveness on lung function, symptom scores, IgE levels and inhaled steroid use. One small study showed a significant difference in % drop in FEV1 post-exercise, according to the study of "Vitamin C supplementation for asthma" by Kaur B, Rowe BH, Arnold E.(5)

6. Tryptophan
Tryptophan is one of the 10 essential amino acids which the body uses to synthesize the proteins for brain cells need, thus enhancing the nerve cells in information transmitting between themselves and cells in the parts of the body that reduces the risk of anxiety and depression, according to the study of "The effects of tryptophan depletion on neural responses to emotional words in remitted depression" by Roiser JP, Levy J, Fromm SJ, Nugent AC, Talagala SL, Hasler G, Henn FA, Sahakian BJ, Drevets WC.(6)

7. Etc.

C. Other health benefits
1. Heart diseases
Fermentation products of sugar-beet fiber reduces bad cholesterol (LDL)by binding to them and expelling through digestive process, thus decreasing the risk of cholesterol plaque building up in the arterial walls. Other than that, beet also contains betaine that helps to lowers the levels of homocysteine, which is harmful to the blood vessels, according to "Fermentation products of sugar-beet fiber by cecal bacteria lower plasma cholesterol concentration in rats" by Hara H, Haga S, Kasai T, Kiriyama S.(I)

2. Prevent birth defect
Beet contains measurable amount of folate, which is essential to prevent neural tube defects by enhancing its functioning in synthesizing and repairing DNA aiding rapid and proper cell division and growth, according to "Folic Acid supplementation and pregnancy: more than just neural tube defectprevention" by Greenberg JA, Bell SJ, Guan Y, Yu YH.(II)

3. Cancer prevention
Since beetroot contains high amount of antioxidants that help to improve the immune function in fighting the forming of free radicals, by enhancing the proper cell replication and division, that reduce the risk of tumors and cancers, according to "Total extract of Beta vulgaris var. cicla seeds versus its purified phenolic components: antioxidant activities and antiproliferative effects against coloncancer cells" by Gennari L, Felletti M, Blasa M, Angelino D, Celeghini C, Corallini A, Ninfali P.(III)

4. Red blood cells
Iron helps to deliver oxygen ans nutrients to the body cells need due to its functioning of the production of red blood cells and formation of hemoglobin of that enhances the absorption of oxygen from the lung.

5. Etc.

Side effects

1. Oxalates Oxalates in the beet can cause kidney and gallbadder problem. People with above diseases should contact their doctor before consuming.
2. Increase the rick of lowering calcium absorption for people with weak digestive system.
3. Etc.

The Best anti inflammatory Smoothie of Raspberry, Olive and Pineapple Juices for Prevention and Treatment of Sarcoidosis

Kyle J. Norton(Scholar, Master of Nutrients), all right reserved.
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

The smoothie for prevention and treatment of Sarcoidosis
Yield: 2 servings (about 8 ounces each)
1  cups of raspberry
1/2 cup olive1 cup of pineapple juice

1. Place all ingredients in a blender and puree about 1 minute
2. Blend on high speed about 1 minute or until the mixture is thick and the ice is well crushed.
3. Serve immediately

The finding of a natural source for treatment of Sarcoidosis has been running into many obstacles, many ingredients showed initially with promising result in animal studies have not produced same potentials in large sample size and mutli centers human trials.

Sarcoidosis, is an inflammatory disease caused by abnormal collections of inflammatory cells (granulomas) induced the form of nodules in multiple organs, including the liver. According to the Maastricht University, patients with sarcoidosis are found to have lower antioxidant defense and exaggerated oxidative stress(1).

Recent studies back by well known institutions proposed, Reishi mushroom and Cooked Artichokes may be the next generation of natural ingredients for prevention and treatment of Primary Biliary Cirrhosis.

Quercetin, antioxidant found in raspberry may consist a beneficial and potential use in reduced inflammation of sarcoidosis, through inhibition of pro inflammatory cytokines(1). According to the University of Maastricht, intake of quercetin reduced the occurring oxidative stress as well as inflammation found in the in the blood of sarcoidosis patients(2).
Due to its inflammatory effects in nature, long term intake anti inflammatory from natural sources may reduce symptoms and for treatment of sarcoidosis, logically.

Bromelain, derived from pineapple with the power of anti anti-inflammation and anti-cancers(3) may be beneficiary for people with inflammatory diseases(3). According to University of Maryland medical center, 500 mg per day of bromelain may reduce inflammation caused in patient with sarcoidosis(4).

ω-3 polyunsaturated fatty acid found abundantly in flax seed oil and olive plays a critical role played by inflammation in the pathogenesis of several diseases(5), through inhibition of production of inflammatory cytokines and improvement of lipid metabolism(5)(6).

The effectiveness of Raspberry, Olive and Pineapple Juices may serve as cornerstones of pharmaceutical target for further studies in production of a potential medication for reduced risk, complications and treatment of sarcoidosis with little or no adverse effects.

People who are at high risk of Sarcoidosis due to aging, weaken immunity, .... should drink at least one serving daily and people with Sarcoidosis should drink the smoothie as much as they can, depending to digestive toleration.

Life style and dietary pattern change are recommended.


References
(1) Antioxidant status associated with inflammation in sarcoidosis: a potential role for antioxidants by Boots AW1, Drent M, Swennen EL, Moonen HJ, Bast A, Haenen GR.(PubMed)
(2) Quercetin reduces markers of oxidative stress and inflammation in sarcoidosis by Boots AW1, Drent M, de Boer VC, Bast A, Haenen GR.(PubMed)
(3) The combination of N-acetyl cysteine, alpha-lipoic acid, and bromelain shows high anti-inflammatory properties in novel in vivo and in vitro models of endometriosis by Agostinis C1, Zorzet S2, De Leo R1, Zauli G1, De Seta F3, Bulla R2.(PubMed)
(4) Sarcoidosis by University of Maryland medical center
(5) Experimental evidence of ω-3 polyunsaturated fatty acid modulation of inflammatory cytokines and bioactive lipid mediators: their potential role in inflammatory, neurodegenerative, and neoplastic diseases by Calviello G1, Su HM, Weylandt KH, Fasano E, Serini S, Cittadini A.(PubMed)
(6) [Anti-inflammatory pro-resolving derivatives of omega-3 and omega-6 polyunsaturated fatty acids].[Article in Polish] by Nowak JZ1.(PubMed)

Most common Diseases of 50plus: The Obesity' Research and Studies of Green tea on weight loss and weight maintenance

Kyle J. Norton(Scholar and Master of Nutrients, all right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

Obesity is a medical condition of excess body fat accumulated overtime, while overweight is a condition of excess body weight relatively to the height. According to the Body Mass Index(BMI), a BMI between 25 to 29.9 is considered over weight, while a BMI of over 30 is an indication of obesity. According to the statistic, 68% of American population are either overweight or obese.

You can calculate your BMI index BMI= weight (kg)/ height (m2)

The Research and Studies of Green tea on weight loss and weight maintenance

There have been different outcomes of the effect of green tea on weight loss (WL) and weight maintenance (WM) have been reported in studies with subjects differing in ethnicity and habitual caffeine intake. In the review conducted by Nutrition and Toxicology Research Institute Maastricht (NUTRIM) Maastricht University(1), out of the 49 studies initially identified, a total of 11 articles fitted the inclusion criteria and provided useful information for the meta-analysis. Effect sizes (mean weight change in treatment versus control group) were computed and aggregated based on a random-effects model. researchers concluded that Catechins significantly decreased body weight and significantly maintained body weight after a period of WL (microcirc=-1.31 kg; P<0.001). Inhibition of this effect by high habitual caffeine intake (>300 mg per day) failed to reach significance (microcirc=-0.27 kg for high and microcirc=-1.60 kg for low habitual caffeine intake; P=0.09). Also, the seemingly smaller effect of catechins in Caucasian (microcirc=-0.82 kg) subjects compared with Asians (microcirc=-1.51 kg; P=0.37) did not reach significance. Interaction of ethnicity and caffeine intake was a significant moderator (P=0.04).

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The Best Way to prevent, treat your disease, including Obesity
and restore your health naturally with Chinese diet

Ovarian Cysts And PCOS Elimination
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Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

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(1) "The effects of green tea on weight loss and weight maintenance: a meta-analysis" by Hursel R, Viechtbauer W, Westerterp-Plantenga MS., posted in PubMed

Most Common Diseases of 50plus: Respiratory Disease: Benign lung tumors - The Causes

Kyle J. Norton(Scholar and Master of Nutrients)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

Respiratory Disease is defined as medical conditions which affect the breathing organ and tissues including Inflammatory lung disease, Obstructive lung diseases, Restrictive lung diseases, Respiratory tract infections, trachea, bronchi, bronchioles, alveoli, the nerves and muscles breathing , etc,.

Benign lung tumors, growth from many different structures in the lung, is defined as a conditions of abnormal cell growth with no tendency of spreading or masses that push normal cells out of the way rather than invading surrounding tissue restricted to a limited area in the lung. Approximately one out of 500 chest radiographs shows the incidental finding of a solitary pulmonary nodule and almost one half of these pulmonary lesions are caused by a tumor. Unfortunately, only 2% to 5% of alllung tumors are of benign origin, e. g. lipoma, fibroma, hamartoma, and chondroma, and the majority are malignant, most commonly primarylung cancer followed by metastases of extrapulmonary primary carcinomas. According to the study by Universitätsklinik für Pneumologie(a).

                       The Causes 

1. Infectious and inflammatory causes of benign lung tumors
a. An infectious fungus such as coccidioidomycosis
Coccidioidomycosis refers to the spectrum of disease caused by the dimorphic fungi Coccidioides immitis and Coccidioides posadasii. Clinical manifestations vary depending upon both the extent of infection and the immune status of the host. Coccidioidomycosis has been reported to involve almost all organ systems; however, pulmonary disease is the most common clinical manifestation. The incidence of coccidioidomycosis continues to rise, and primary coccidioidal pneumonia accounts for 17 to 29% of all cases of community-acquired pneumonia in endemic regions. The majority of patients with coccidioidomycosis resolve their initial infection without sequelae; however, several patients develop complications of disease ranging in severity from complicated pulmonary coccidioidomycosis to widely disseminated disease with immediately life-threatening manifestations, according to the study by the University of California-Davis(5).

Other study report a case of a 61-year-old gentleman presented with shortness of breath, cough, weight loss, but no fever or hemoptysis. His physical exam was unremarkable except for decreased air entry on both lung fields, and axillary and inguinal lymphadenopathies. Computed tomography of the chest showed bilateral cavitary lung lesions, biopsy of which showed non caseating granulomas, and tissue culture showing Histoplasma capsulatum(6). 

b. Tuberculosis (TB)
Chordoma is an uncommon tumor initially believed to be benign due to the rarity of its metastasis. Cytological, morphological, and immunohistochemical features of chordoma, relating to its origin from notochordal remnants, allows for its accurate diagnosis. According to the study by University of Saskatchewan, there is a report of a 75-year-old man with a known history of tuberculosis (TB) presented with shortness of breath and a dry cough. A chest X-ray demonstrated a diffuse, infiltrative miliary pattern in both lungs. Bronchial washings submitted for culture and cytological examination did not identify any tuberculous bacilli. Fine needle aspiration cytology (FNAC) showed focal areas of myxoid regions with small, round, uniform mononuclear cells. There was a documented past history of chordoma arising from the L2 vertebrae. Because of the rarity of this lesion in the lung and the limited diagnostic material available with a clinical history of TB and lumbar chordoma, the pathological report rendered on the FNAC was “atypical cells suspicious for metastatic chordoma(7).

c. A lung abscess
Capnocytophaga species are known commensals of the oral cavity of humans and animals (mainly dogs and cats) and are a rare cause of respiratory tract infections. There is a report of a case of cavitary lung abscess caused by a Capnocytophaga species in a patient with a metastatic neuroendocrine tumor, according to the study by Memorial Sloan-Kettering Cancer Center(8).

d. Round pneumonia
The differential diagnose between round pneumonia and a neoplastic process is difficult to make. In this report, all of cases of round pneumonia have resolved clinically and radiographically with antibiotic therapy, according to the study by (9).

e. Parasitic infections
According to the study by Department of Surgery, Mayo Clinic, Multiple benign pulmonary nodules are rare and are from a variety of etiologies. Infectious causes, such as histoplasmosis, tuberculosis, or parasitic infections, usually require biopsy for confirmation(9a).

2. Diseases casues of benign lung tumors
d. Rheumatoid arthritis
In the study to examine the role of lung disease in rheumatoid arthritis from a clinical, epidemiologic, pathophysiologic, and therapeutic perspective, showed that lung disease in rheumatoid arthritis is a heterogeneous and oftentimes serious condition, with a profound impact on patient wellbeing and survival. Advances in the understanding of its etiology and targeted application of available, as well as development of new, more specific therapeutics will be of benefit to patients with rheumatoid arthritis who are suffering from lung disease(10).

e. Wegener granulomatosis
Wegener’s granulomatosis is a type of vasculitis, or inflammation of the blood vessels. Wegener’s granulomatosis is a systemic vasculitis that primarily involves the upper and lower respiratory tracts and kidneys. Pulmonary Wegener’s granulomatosis can present with multifocal lung involvement or solitary lung lesions with no evidence of extrapulmonary disease, according to the study by the research team of Dr. S Uppal.(11).

f. Sarcoidosis
There is a report of a case of a 65-year-old woman with a high initial index of suspicion for lung malignancy. Clinicians should always be aware that sarcoidosis enters the differential diagnosis of patients presenting with a lung mass that encases and narrows bronchial and vascular structures with associated pericardial effusion. Rarely, pleural effusion can be the presenting symptom of disease relapse despite maintenance treatment(12).

g. Leiomyoma
Benign metastasizing leiomyoma, is rare but occurs from a low-grade leiomyoma that most commonly spreads from the uterus(13).

h. Meningiomas
Meningiomas are generally benign tumors, but rarely metastasize outside of the central nervous system. There is a report of a 25-year-old female was admitted to our institute because of an abnormal shadow on her chest x-ray. A computed tomography (CT) scan showed a 3-cm, well- circumscribed mass in the right lower lobe of the lung. We performed thoracotomy and resected three pulmonary tumors at the right lung and diaphragm. Histological examination revealed a benign meningothelial meningioma. Six months later, she complained of heaviness of her head and a head CT scan revealed an intracranial mass(13a).

3. Birth defected causes of benign lung tumors
The relationship between congenital cystic adenomatoid malformation (CCAM) and pleuropulmonary blastoma (PPB), whether causal, correlational, or coincidental, remains controversial. In the study of Seventy-four CCAMs resected over the study period in 129 children diagnosed with CCAM. Five PPBs were diagnosed during the study period. Three of the 5 PPB cases were initially diagnosed as CCAMs. These PPBs were not clinically or radiologically distinguishable from CCAMs, found that asymptomatic cystic lung malformations represent a therapeutic dilemma. In this cohort, the incidence of PPB among apparently benign lung lesions was 4%. No clinical or radiological markers differentiated benign CCAMs from PPBs. Our experience provides further justification for resection of all CCAMs(14).


Chinese Food Therapy
The Best Way to prevent, treat your disease, including Obesity
and restore your health naturally with Chinese diet

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Super foods Library, Eat Yourself Healthy With The Best of the Best Nature Has to Offer


Sources
(a) http://www.ncbi.nlm.nih.gov/pubmed/22753285
(5) http://www.ncbi.nlm.nih.gov/pubmed/22167403
(6) http://www.ncbi.nlm.nih.gov/pubmed/23198458
(7) http://www.ncbi.nlm.nih.gov/pubmed/22081530
(8) http://www.ncbi.nlm.nih.gov/pubmed/22075586
(9) http://www.ncbi.nlm.nih.gov/pubmed/18537020
(9a) http://www.ncbi.nlm.nih.gov/pubmed/12973710
(10) http://www.ncbi.nlm.nih.gov/pubmed/18388528
(11) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1119387/
(12) http://www.ncbi.nlm.nih.gov/pubmed/22937889
(13) http://www.ncbi.nlm.nih.gov/pubmed/12973710
(13a) http://www.ncbi.nlm.nih.gov/pubmed/23364223
(14) http://www.ncbi.nlm.nih.gov/pubmed/20620300

General Health: Candida Albicans: Treatment - Chinese Herbs for Upper and Middle burner causes of Candida Albicans Overgrowth

Kyle J. Norton(Scholar and Master of Nutrients, all right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

What is Candida Albicans

Candida albicans are members of a large group of micro organism whose cells contain complex structures enclosed within the membranes, including yeast(2)(3), fungi(4)(5)(6), and mold(6) that live among the gut flora in the human mouth and gastrointestinal tract. In fact, under normal circumstances, Candida albicans that do not cause harmful effects, but overgrowth results in candidiasis. Non-albicansCandida (NAC) species cause 35-65% of all candidaemias in the general patient population(1). According to joint study, in many cases, biofilm(microorganisms with cells stick to each other on a surface) formation(7) gene mutations(8) and overexpression of genes(9)(10) are often associated with increased Candidaresistance toward antifungal agents.


                                  Treatment

In Traditional Chinese Medicine 
In traditional Chinese medicine, candidiasis is defined as a malfunction of the Triple Burner-related condition due to spleen and stomach disorder(401), causing excess fluid or phlegm in our system(402), weakening immune system(403)(402), leading to damp heat accumulates in the Lower, Middle and Upper Burner causes of candidiasis(401).


                        Cleansing TCM Herbs


Overgrowth of candida in TCM is considered as the accumulation of waste, phlegm and damp heat, toxins due to inability of spleen and stomach in digesting foods properly(401).



Chinese herbs for Upper and Middle burner disorder causes of Candida albicans overgrowth
1. Huang Lian (Rhizoma Coptidis)
Huang lian is aslo known as Canker roots, a genus of Coptis in the family Ranunculaceae, native to Asia and North America. The bitter and cool herb has been used in TCM as anti microbial(462)(463)(464)Including Candica albicans(465)(466), anti inflammatory(467)(468), antidiabetic(469)(470), anti palette coagulative(461) agents and to treat irritable bowel syndrome(471), inflammation of intestine and diarrhea(460) caused by bacterial infection by clearing heat(460)(461), drying damp(460)(461), dispersing fire and expelling toxins(460) as it promotes the functions of heart, large intestine, liver, and stomach channels(461).


2. Da Huang (Radix et Rhizoma Rhei)
Da Huang is also known as Ruhbarb, is a genus Rheum, belonging the family Polygonaceae. The bitter and cold herb has been used in TCM to treat diarrhoea(472), bowel movement(473), aging induced dementia(474), tumor(475), abdominal-distention and/or pain(476), hemorrhoidal bleeding(476) and urination burning sensation(476), bacterial infection(477) and improve blood circulation(477), by clearing damp heat(477), expelling toxins(478)(480) and invigorating blood(477) as it promotes the functions of heart, large intestine, liver, stomach channels(476). According to Advances in Viridans Streptococci Research and Treatment: 2011 Edition, da huang showed to exhibit antimicrobial activity against many strains of bacterias(479), including candida albicans(480).

3. Huang Bai (Cortex Phellodendri)
Huang Bai is also known as Cork-tree, a genus of Phellodendra, belonging to the family Rutaceae, native to east and northeast Asia. The bitter and cold herb has been used in TCM as anti microbial(481)(482)(483), including candida albicans(484)(485), anti inflammatory(486)(487) and anti trichomoniasis(488), to lower blood pressure(489) and blood sugar(490) by
clearing damp heat(481) in the lower burner due to bacterial infection(480), dispersing fire(480) and expeling toxins(480) as it promotes the functions of kidney and bladder channels(488).

4. Shi Gao (Herba Achilleae alpinae)
Shi Gao is also known as Gypsum, a very soft mineral composed of calcium sulfate dihydrate. The bitter, very cod and acrid herb has been used in TCM as antipyretics(492), antimicrobial(496)(497) including candida albicans(498)and to treat asthma(492), relieve pain(493)(494) and diabetes(495) by clearing and fire(499), as it promotes the functions of lung, kidney channels(500).

5. Lian Qiao (Fructus Forsythiae Suspensae)
Lian Qiao is also known as Forsythia fruit, is a genus of Forsythia, belongs to the family Oleaceae, native to Eastern Asia. The bitter, cold and slightly acrid herb has been used as spectrum antibiotic(501)(502)(503), antioxidant(502)(503), inflammatory(504)(505) agents and to treat asthma(506), lower fever(507), cholesterol(509) and to protect liver(510) by clearing heat and toxins, and resolving abscesses as it promotes the functions of heart, liver and gallbladder channels(508).

6. Ju Hua (Flos Chrysanthemi Morifolii)
Ju Hua also known as chrysanthemum flower, a genus of chrysanthemum, belongs to the family Asteraceae, native to Asia and northeastern Europe. The sweet, bitter and slightly cold herb has been used in TCM as anti-inflammatory(511)(512)(513), antibiotic(514)(515), including andida albicans(519), analgesic(516) and antipyretic(517) agents and to benefit diabetes(518) by expelling wind, clearing heat and toxins as it promotes the functions of lung and liver channels(517).

7. Bo He (Herba Menthae Haplocalycis)
Bo he is also known as Mint, a genus of Mentha, belonging to the family Lamiaceae, native to the through the world. The acrid and cold herb has been used in TCM as anti-pyretic(520), antinociceptive(520)(521), antimicrobial(522)(523) including candida albicans(524)(525), antioxidant(522)(523) anti-inflammatory(526)(527) agents and to treat wind-heat(528) cause of infection(522)(523) by dispersing wind-heat(528) and clearing fire(528) as it promotes the functions of liver and lung channels(529).

8. Gan Cao (Radix Glycyrrhizae Uralensis)
Gan Cao is also known as Licorice, a genus of Glycyrrhiza, belonging to the familyFabaceae, native to southern Europe and parts of Asia. The sweet herb has been used in TCM as anti microbial(530)(531)(532), including candida akbicans(533)(534), antioxidant(530)(531), inflammatory(536)(537), and anti allergic(538)(539)(540) agents by tonifying spleen, benefiting qi, moistening lung as it promotes all 12 channels(535).

9. Etc.


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(488) Huang bai(Complementary and Alternative Healing University)
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(493) Treatment of painful Modic type I changes by vertebral augmentation with bioactive resorbable bone cement by Masala S1, Anselmetti GC, Marcia S, Nano G, Taglieri A, Calabria E, Chiocchi M, Simonetti G.(PubMed)
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(499) Herbs that c;ear heat(Chapter 3)
(500) Shi Gao (Complementary and Alternative Healing University)
(501) Chemical constituents from the fruits of Forsythia suspensa and their antimicrobial activity by Kuo PC1, Chen GF2, Yang ML3, Lin YH1, Peng CC1.(PubMed)
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(508) Lian qiao (Complementary and Alternative Healing University)
(509) Effects of forsythia fruit extracts and lignan on lipid metabolism by Cho SH1, Rhee SJ, Choi SW, Choi Y.(PubMed)
(510) Protective effects of Forsythia suspensa extract against oxidative stress induced by diquat in rats. Lu T1, Piao XL, Zhang Q, Wang D, Piao XS, Kim SW.(PubMed)
(511) Anti-inflammatory components of Chrysanthemum indicum flowers by Luyen BT1, Tai BH2, Thao NP2, Cha JY3, Lee HY3, Lee YM4, Kim YH5.(PubMed)
(512) Chrysanthemum indicum Linné extract inhibits the inflammatory response by suppressing NF-kappaB and MAPKs activation in lipopolysaccharide-induced RAW 264.7 macrophages by Cheon MS1, Yoon T, Lee do Y, Choi G, Moon BC, Lee AY, Choo BK, Kim HK.(PubMed)
(513) Suppression of inflammatory responses by handelin, a guaianolide dimer from Chrysanthemum boreale, via downregulation of NF-κB signaling and pro-inflammatory cytokine production by Pyee Y1, Chung HJ, Choi TJ, Park HJ, Hong JY, Kim JS, Kang SS, Lee SK.(PubMed)
(514) Rapid green synthesis of silver nanoparticles from Chrysanthemum indicum L and its antibacterial and cytotoxic effects: an in vitro study by Arokiyaraj S1, Arasu MV2, Vincent S3, Prakash NU4, Choi SH5, Oh YK1, Choi KC2, Kim KH6.(PubMed)
(515) Composition and antibacterial activity of essential oils from leaf, stem and root of Chrysanthemum parthenium (L.) Bernh. from Iran by Shafaghat A1, Sadeghi H, Oji K.(PubMed)
(516) Analgesic activity of the aqueous fraction from the ethanolic extract of Chrysanthemum indicum in mice by Chen YF1, Zhao MH, Yan M, Shi GB, Hou GX, Huang Y, Wang X, Zhao QC.(PubMed)
(517) Ju hua (Complementary and Alternative Healing University)
(518) Chrysanthemum Promotes Adipocyte Differentiation, Adiponectin Secretion and Glucose Uptake by Yamamoto J1, Yamane T, Oishi Y, Shimizu M, Tadaishi M, Kobayashi-Hattori K.(PubMed)
(519) The chemical constituents of endophytic fungus Trichoderma sp. MFF-1 by Li GH1, Wang XB, Liu FF, Dang LZ, Li L, Yang ZS, Xin X, Zhang KQ.(PubMed)
(520) Antipyretic and antinociceptive properties of Mentha longifolia Huds. (Lamiaceae) leaf aqueous extract in rats and mice by Amabeoku GJ1, Erasmus SJ, Ojewole JA, Mukinda JT.(PubMed)
(521) Antinociceptive activity of Mentha piperita leaf aqueous extract in mice by Taher YA1.(PubMed)
(522) Antimicrobial and antioxidant activities of three Mentha species essential oils. Mimica-Dukić N1, Bozin B, Soković M, Mihajlović B, Matavulj M.(PubMed)
(523) Chemical composition and antimicrobial and antioxidant activities of Mentha (longifolia L. and viridis) essential oils by Mkaddem M1, Bouajila J, Ennajar M, Lebrihi A, Mathieu F, Romdhane M.(PubMed)
(524) Effects of Mentha suaveolens Essential Oil Alone or in Combination with Other Drugs in Candida albicans by Stringaro A1, Vavala E2, Colone M1, Pepi F3, Mignogna G4, Garzoli S3, Cecchetti S5, Ragno R3, Angiolella L2.(PubMed)
(525) Anti-Candida activity of Mentha arvensis and Turnera ulmifolia by Santos KK1, Matias EF, Souza CE, Tintino SR, Braga MF, Guedes GM, Nogueira LF, Morais EC, Costa JG, Menezes IR, Coutinho HD.(PubMed)
(526) Chemical Composition and Anti-Inflammatory, Cytotoxic and Antioxidant Activities of Essential Oil from Leaves of Mentha piperita Grown in China by Sun Z1, Wang H2, Wang J3, Zhou L3, Yang P1.(PubMed)
(527) Anti-inflammatory effect of Mentha longifolia in lipopolysaccharide-stimulated macrophages: reduction of nitric oxide production through inhibition of inducible nitric oxide synthas by Karimian P1, Kavoosi G, Amirghofran Z.(PubMed)
(528) Pocket Atlas of Chinese Medicine By Marnae C. Ergil, page 269
(529) Bo he(Complementary and Alternative Healing University)
(530) Identification of antimicrobial and antioxidant constituents from licorice of Russian and Xinjiang origin by Okada K, Tamura Y, Yamamoto M, Inoue Y, Takagaki R, Takahashi K, Demizu S, Kajiyama K, Hiraga Y, Kinoshita T.(PubMed)
(531) Antioxidant and antimicrobial constituents of licorice: isolation and structure elucidation of a new benzofuran derivative by Demizu S, Kajiyama K, Takahashi K, Hiraga Y, Yamamoto S, Tamura Y, Okada K, Kinoshita T.(PubMed)
(532) Antimicrobial flavonoids from Glycyrrhiza glabra hairy root cultures by Li W, Asada Y, Yoshikawa T.(PubMed)
(533) 18β-glycyrrhetinic acid induces immunological adjuvant activity of Th1 against Candida albicans surface mannan extract by Kim J1, Joo I, Kim H, Han Y.(PubMed)
(534) Effect of licorice compounds licochalcone A, glabridin and glycyrrhizic acid on growth and virulence properties of Candida albicans by Messier C1, Grenier D.(PubMed)
(535) Gan cao(Complementary and Alternative Healing University)
(536) Glabridin, An isoflavan from licorice root, down-regulates iNOS expression and activity under high glucose stress and inflammation by Yehuda I1, Madar Z, Leikin-Frenkel A, Tamir S.(PubMed)
(537) Anti-inflammatory effects of Huangqin tang extract in mice on ulcerative colitis by Chen P1, Zhou X2, Zhang L2, Shan M2, Bao B2, Cao Y2, Kang A2, Ding A2.(PubMed)
(538) Modulatory effects of several herbal extracts on avian peripheral blood cell immune responses by Dorhoi A1, Dobrean V, Zăhan M, Virag P.(PubMed)
(539) Attenuation of allergic airway inflammation in a murine model of asthma by Licochalcone A by Chu X1, Jiang L, Wei M, Yang X, Guan M, Xie X, Wei J, Liu D, Wang D.(PubMed)
(540) Interaction of gypsum and the rhizome of Anemarrhena asphodeloides plays an important role in anti-allergic effects of byakkokakeishito in mice by Makino T1, Shiraki Y, Mizukami H.(PubMed)

Phytochemicals In Foods: The effects of Omega-3, 6,9 fatty acids

Kyle J. Norton(Scholar and Master of Nutrients, all right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

                    Omega-3, 6,9 fatty acids

Omega-3, 6,9 fatty acids are phytochemincals in the class of Lipids, found abundantly in dark-green leafy vegetables, grains, legumes, nuts, etc.

Health Benefits
1. Vascular smooth muscle tone
In the investigation of the comparative effects of omega-3, omega-6 and omega-9fatty acids on vascular smooth muscle tone, showed that Docosahexaenoic acid (1-255 microM) and eicosapentaenoic acid (31-255 microM) inhibited phenylephrine-induced contractions, (8-63%) and (20-65%), respectively, which were not altered by indomethacin, NDGA, or by removal of the endothelium. Linoleic acid (18:2n6) and arachidonic acid (20:4n6) also induced significant relaxation. Therefore, fatty acid-induced relaxation of the rat aorta is specific to polyunsaturated fatty acids, 20:5n3, 22:6n3, 18:2n6 and 20:4n6, according to "Effects of omega-3, omega-6 and omega-9 fatty acids on vascular smooth muscle tone" by Engler MB.(1)

2. Breast cancer
In the review of the literature concerning the role of fatty acids and eicosanoid synthesis inhibitors in breast carcinoma, indicated that The omega-6 polyunsaturated fatty acids (PUFAs), primarily linoleic acid, promote breast cancer tumorigenesis and tumor cell proliferation directly and indirectly via increased synthesis of cyclooxygenase- and lipoxygenase-catalyzed products. The omega-3PUFAs, primarily docosahexaenoic acid (DHA) and eicosapentaenoic acid (EPA), suppress breast carcinoma tumorigenesis and tumor cell proliferation, although the effect of DHA may be partly ascribed to increased amounts of EPA derived from DHA. Both cyclooxygenase and lipoxygenase inhibitors suppress tumorigenesis and/or tumor proliferation, with the latter being more active. Thus, arachidonic acid-derived eicosanoids play an important role in breast cancer, and the balance of the various eicosanoids may be a critical determinant of cell proliferation, according to "The role of fatty acids and eicosanoid synthesis inhibitors in breast carcinoma" by Noguchi M, Rose DP, Earashi M, Miyazaki I.(2)

3. Regulatory effects
In the examination of the effects of individual n-6 (linoleic acid) and n-3 (alpha-linolenic, eicosapentaenoic, and docosahexaenoic acid) PUFAs on plasma lipid levels and on the major transport processes that determine plasma LDL concentrations, found that Rats were fed a semisynthetic cholesterol-free diet supplemented with 4% (by wt) linoleic, alpha-linolenic, eicosapentaenoic, or docosahexaenoic acid for 2 weeks. Dietary eicosapentaenoic and docosahexaenoic acids lowered plasma triglyceride concentrations by 62% and 52%, respectively, and lowered plasma cholesterol concentrations by 54% and 43%, respectively. In contrast, dietary linoleic and alpha-linolenic acids had relatively little effect on plasma triglyceride or cholesterol concentrations. Dietary eicosapentaenoic and docosahexaenoic acids increased hepatic LDL receptor activity by 72% and 58%, respectively, and reduced the rate of LDL cholesterol entry into plasma by 36% and 30%, respectively, according to "Regulatory effects of individual n-6 and n-3 polyunsaturated fatty acids on LDL transport in the rat" by Spady DK.(3)

4. Systolic blood pressure, triglycerides and LDL cholesterol
In the ccomparison of the cardiovascular risk-reduction potential of three major polyunsaturated fatty acids in a double-blind study. showed that for the diet supplemented with EPA plus DHA compared with the linoleic acid diet systolic blood pressure fell 5.1 mm Hg (p = 0.01); plasma triglyceride and VLDL cholesterol fell by 39% (p = 0.001) and 49% (p = 0.01), respectively; and LDL cholesterol rose by 9% (p = 0.01). There were no significant changes with the diet supplemented with alpha-linolenic acid. The net effect on cardiovascular risk therefore is complex and the systolic blood pressure reduction was substantial, according to "n-3 fatty acids of marine origin lower systolic blood pressure and triglycerides but raise LDL cholesterol compared with n-3 and n-6 fatty acids from plants" by Kestin M, Clifton P, Belling GB, Nestel PJ.(4)

5. Cardiovascular effects
In the comparison of the effects of alpha-linolenic acid (ALA, C18:3n-3) to those of eicosapentaenoic acid (EPA, C20:5n-3) plus docosahexaenoic acid (DHA, C22:6n-3) on cardiovascular risk markers in healthy elderly subjects, found that Both n-3fatty acid diets did not change concentrations of total-cholesterol, LDL-cholesterol, HDL-cholesterol, triacylglycerol and apoA-1 when compared with the oleic acid-rich diet. However, after the EPA/DHA-rich diet, LDL-cholesterol increased by 0.39 mmol/l (P = 0.0323, 95% CI (0.030, 0.780 mmol/l)) when compared with the ALA-rich diet. Intake of EPA/DHA also increased apoB concentrations by 14 mg/dl (P = 0.0031, 95% CI (4, 23 mg/dl)) and 12 mg/dl (P = 0.005, 95% CI (3, 21 mg/dl)) versus the oleic acid and ALA-rich diet, respectively. Except for an EPA/DHA-induced increase in tissue factor pathway inhibitor (TFPI) of 14.6% (P = 0.0184 versus ALA diet, 95% CI (1.5, 18.3%)), changes in markers of hemostasis and endothelial integrity did not reach statistical significance following consumption of the two n-3 fatty acid diets, according to "Effects of alpha-linolenic acid versus those of EPA/DHA on cardiovascular risk markers in healthy elderly subjects" by Goyens PL, Mensink RP.(5)

6. Cognitive effects
In the assessment of the cognitive effects of fish oil supplementation at college age, hypothesizing benefits on affect, executive control, inhibition, and verbal learning and memory. College-aged participants, indicated that the benefits of n-3 PUFA on RAVLT performance derived more from depreciated placebo performance than improved performance due to fish oil. The placebo gain on TMT performance likely derived from a learning effect. Together, these results present limited cognitive benefits of n-3 PUFA at college age; however, the treatment may have been subtherapeutic, with a larger sample needed to generalize these results, according to "Omega-3 polyunsaturated fatty acids and cognition in a college-aged population" by Karr JE, Grindstaff TR, Alexander JE.(6)

7. Depression-related cognition
In the investigation of the effects of n-3 PUFA on depression-relevant cognitive functioning in healthy individuals, found that The n-3 PUFA group made fewer risk-averse decisions than the placebo group. This difference appeared only in non-normative trials of the decision-making test, and was not accompanied by increased impulsiveness. N-3 PUFAs improved scores on the control/perfectionism scale of the cognitive reactivity measure. No effects were found on the other cognitive tasks and no consistent effects on mood were observed. The present findings indicate that n-3 PUFA supplementation may have a selective effect on risky decision making in healthy volunteers, which is unrelated to impulsiveness, according to "Omega-3 fatty acids (fish-oil) and depression-related cognition in healthy volunteers" by Antypa N, Van der Does AJ, Smelt AH, Rogers RD.(7)

8. Mental illness
In the review of the double blind placebo controlled clinical trials published prior to April 2007 to determine whether omega-3 PUFA are likely to be efficacious in these psychiatric disorders, found that for schizophrenia and borderline personality disorder we found little evidence of a robust clinically relevant effect. In the case of attention deficit hyperactivity disorder and related disorders, most trials showed at most small benefits over placebo. A limited meta-analysis of these trials suggested that benefits of omega-3 PUFA supplementation may be greater in a classroom setting than at home. Some evidence indicates that omega-3 PUFA may reduce symptoms of anxiety although the data is preliminary and inconclusive. The most convincing evidence for beneficial effects of omega-3PUFA is to be found in mood disorders. A meta-analysis of trials involving patients with major depressive disorder and bipolar disorder provided evidence that omega-3 PUFA supplementation reduces symptoms of depression. Furthermore, meta-regression analysis suggests that supplementation with eicosapentaenoic acid may be more beneficial in mood disorders than with docosahexaenoic acid, although several confounding factors prevented a definitive conclusion being made regarding which species of omega-3 PUFA is most beneficial, according to "Omega-3 fatty acids as treatments for mental illness: which disorder and which fatty acid?" by Ross BM, Seguin J, Sieswerda LE.(8)

9. Antioxidant, antimicrobial activities
In the investigation of the hexane extract from different parts in several Hypericum species, found that The antioxidant activity of all hexane extracts was evaluated by the 2,2-diphenyl-1-picrylhydrazyl (DPPH) radical scavenging method. The results indicate that hexane extracts from different parts of H. scabrum possess considerable antioxidant activity. The highest radical scavenging activity was detected in seed, which had an IC50 = 165 microg/mL. The antimicrobial activity of the extracts of those samples were determined against seven Gram-positive and Gram-negative bacteria (Bacillus subtilis, Enterococcus faecalis, Staphylococcus aureus, S. epidermidis, Escherichia coli, Pseudomonas aeruginosa, and Klebsiella pneumoniae), as well as three fungi (Candida albicans, Saccharomyces cerevisiae, and Aspergillus niger), according to "Antioxidant, antimicrobial activities and fatty acid components of flower, leaf, stem and seed of Hypericum scabrum" by Shafaghat A.(9)

10. Post-partum depression PPD
In the investigation of the effect of unbalanced dietary intake of omega-6/omega-3ratio >9:1 in the prevalence for PPD, comprising a prospective cohort with four waves of follow-up during pregnancy and one following delivery. PPD was evaluated according to the Edinburgh Post-partum Depression Scale (PPD ≥ 11) in 106 puerperae between 2005 and 2007, in Rio de Janeiro, Brazil. Independent variables included socio-demographic, obstetric, pre-pregnancy body mass index (BMI) and dietary intake data, which were obtained by means of a food frequency questionnaire in the first trimester of pregnancy, verified that an association between omega-6/omega-3 ratio above 9:1, the levels recommended by the Institute of Medicine, and the prevalence of PPD. These results add to the evidence regarding the importance of omega-6 and omega-3 fatty acids in the regulation of mental health mechanisms, according to "High dietary ratio of omega-6 to omega-3 polyunsaturated acids during pregnancy and prevalence of post-partum depression" by da Rocha CM, Kac G.(10)

11. Relieving inflammation
In the evaluation of the effects of lymphatic drainage and omega-3 polyunsaturatedfatty acid (omega-3PUFA) on high mobility group box 1 (HMGB1), inflammatory cytokines and endotoxin in rats with intestinal ischemia-reperfusion (I/R) injury, found that Lymphatic drainage may reduce the levels of endotoxin, inflammatory cytokines and HMGB1 so as to alleviate the intestinal I/R injury. The intervention of omega-3PUFA has some protective effect through relieving inflammation, according to "[Effects of lymphatic drainage and omega-3 polyunsaturatedfatty acids on intestinal ischemia-reperfusion injury in rats].[Article in Chinese]" by Zhou KG, He GZ, Zhang R, Chen XF.(11)

12. Suppression of inflammatory
In the determination of whether salmon (rich in n-3 LCPUFAs) consumption twice a week during pregnancy affected offspring umbilical vein EC CAM expression, showed that increased dietary salmon intake in pregnancy dampens offspring EC activation, which implicates a role for n-3 LCPUFAs in the suppression of inflammatory processes in humans. This trial was registered at clinicaltrials.gov as NCT00801502, according to "Salmon consumption by pregnant women reduces ex vivo umbilical cord endothelial cell activation" by van den Elsen LW, Noakes PS, van der Maarel MA, Kremmyda LS, Vlachava M, Diaper ND, Miles EA, Eussen SR, Garssen J, Willemsen LE, Wilson SJ, Godfrey KM, Calder PC.(12)

13. Neonatal immune responses
In thye assessment of whether an increased intake of oily fish in pregnancy modifies neonatal immune responses and early markers of atopy, showed that Oily fish intervention in pregnancy modifies neonatal immune responses but may not affect markers of infant atopy assessed at 6 mo of age, according to "Increased intake of oily fish in pregnancy: effects on neonatal immune responses and on clinical outcomes in infants at 6 mo" by Noakes PS, Vlachava M, Kremmyda LS, Diaper ND, Miles EA, Erlewyn-Lajeunesse M, Williams AP, Godfrey KM, Calder PC.(13)

14. Allergic disease
In the study of the effects of maternal n-3 (PUFA)-rich fish oil supplementation on cord blood (CB) IgE and cytokine levels in neonates at risk of developing allergic disease, found that increasing neonatal n-3 PUFA levels with maternal dietary supplementation can achieve subtle modification of neonatal cytokine levels. Further assessment of immune function and clinical follow-up of these infants will help determine if there are any significant effects on postnatal immune development and expression of allergic disease, according to " Maternal fish oil supplementation in pregnancy reduces interleukin-13 levels in cord blood of infants at high risk of atopy' by Dunstan JA, Mori TA, Barden A, Beilin LJ, Taylor AL, Holt PG, Prescott SL.(14)

15. Mucosal immune function
In the evaluation of if changes in breast milk omega-3 polyunsaturated fatty acid (n-3 PUFA) composition as a result of maternal dietary fish oil supplementation during pregnancy can modify levels of these immunological parameters in breast milk, found that Supplementation with fish oil during pregnancy significantly alters early post-partum breast milk fatty acid composition. omega-3 PUFA levels were positively associated with IgA and sCD14 levels, suggesting a relationship between fatty acid status and mucosal immune function, according to "The effect of supplementation with fish oil during pregnancy on breast milk immunoglobulin A, soluble CD14, cytokine levels and fatty acid composition" by Dunstan JA, Roper J, Mitoulas L, Hartmann PE, Simmer K, Prescott SL.(15)

16. Ventricular arrhythmias and myocardial infarction
In the investigation of the effectiveness of prescription medication containing 90%omega-3 polyunsaturated fatty acids for 6 months on ventricular arrhythmias in patients with myocardial infarction less than a year ago, found that Administration of highly concentration preparation of omega-3 PUFAs for 3 months reduced number of PVCs per day, frequencies of grades 2, 3, 4A, 4B, and high grade PVCs (grades 3 - 5) as a whole. These effects persisted after 6 months of treatment, according to "[Possibilities of a preparation omega-3 polyunsaturatedfatty acids in the treatment of patients with ventricular arrhythmias and myocardial infarction].[Article in Russian]" by Gogolashvili NG, Litvinenko MV, Pochikaeva TN, Vavitova ES, Polikarpov LS, Novgorodtseva NIa.(16)

17. Health effects
In the investigation of the health effects of Perilla frutescens seeds, a good source of polyunsaturated fatty acids (PUFAs), showed that in comparing to other plant oils, perilla seed oil consistently contains the one of the highest proportion ofomega-3 (ALA) fatty acids, at 54-64%. The omega-6 (linoleic acid) component is usually around 14% and omega-9 (Oleic acid) is also present in perilla oil. These polyunsaturated fatty acids are most beneficial to human health and in prevention of different diseases like cardiovascular disorders, cancer, inflammatory, rheumatoid arthritis etc., according to "Health effects of omega-3,6,9 fatty acids: Perilla frutescens is a good example of plant oils" by Asif M.(17)

18. Obesity
in the determination of whether obesity modifies the association between plasma phospholipid polyunsaturated fatty acids (PUFAs) and markers of inflammation and endothelial activation in Multi-Ethnic Study of Atherosclerosis (MESA) participants, found that the modifying effect of obesity on the association of plasma PUFAs with IL-6 and sICAM-1 suggests differences in fatty acid metabolism and may also have implications in dietary fatty acid intake for obese individuals, particularly for linoleic and EPAs. Further study is warranted to confirm and explain the strong associations of dihomo-γ-linolenic acid (DGLA) with inflammatory and endothelial activation markers, according to "Obesity modifies the association between plasma phospholipid polyunsaturated fatty acidsand markers of inflammation: the Multi-Ethnic Study of Atherosclerosis" by Steffen BT, Steffen LM, Tracy R, Siscovick D, Hanson NQ, Nettleton J, Tsai MY.(18)

19. Crohn's disease (CD)
In the investigation of the effects of a nutritionally balanced inflammatory bowel disease nutrition formula (IBDNF) on nutrition status in CD patients, indicate that twenty patients completed the final visit. After 4 months, there was a significant decrease in plasma phospholipid levels of arachidonic acid with increases in eicosapentaenoic acid (EPA) and docosahexaenoic acid. Ten patients had a final EPA concentration of >2%. There was improvement in fat-free and fat mass in patients with final EPA >2% (P = .014 and P = .05). Vitamin D (25-OH) levels improved in all patients (18.5-25.9 ng/mL, P < .001). Those with EPA >2% had significantly lower CDAI (116 ± 94.5 vs 261.8 ± 86.5; P = .005) and higher IBDQ (179.1 ± 26.6 vs 114.6 ± 35.9, P < .001) compared to those with EPA <2%, according to "The effects of an oral supplement enriched with fish oil, prebiotics, and antioxidants on nutrition status in Crohn's disease patients" by Wiese DM, Lashner BA, Lerner E, DeMichele SJ, Seidner DL.(19)

20. Etc.

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Sources
(1) http://www.ncbi.nlm.nih.gov/pubmed/1396998
(2) http://www.ncbi.nlm.nih.gov/pubmed/7777237
(3) http://www.ncbi.nlm.nih.gov/pubmed/8105015
(4) http://www.ncbi.nlm.nih.gov/pubmed/1971991
(5) http://www.ncbi.nlm.nih.gov/pubmed/16482073
(6) http://www.ncbi.nlm.nih.gov/pubmed/22250656
(7) http://www.ncbi.nlm.nih.gov/pubmed/18583436
(8) http://www.ncbi.nlm.nih.gov/pubmed/17877810
(9) http://www.ncbi.nlm.nih.gov/pubmed/22224301
(10) http://www.ncbi.nlm.nih.gov/pubmed/22136220
(11) http://www.ncbi.nlm.nih.gov/pubmed/22093738
(12) http://www.ncbi.nlm.nih.gov/pubmed/22011457
(13) http://www.ncbi.nlm.nih.gov/pubmed/22218160
(14) http://www.ncbi.nlm.nih.gov/pubmed/12680858
(15) http://www.ncbi.nlm.nih.gov/pubmed/15298564
(16) http://www.ncbi.nlm.nih.gov/pubmed/21942955
(17) http://www.ncbi.nlm.nih.gov/pubmed/21909287
(18) http://www.ncbi.nlm.nih.gov/pubmed/21829163
(19) http://www.ncbi.nlm.nih.gov/pubmed/21775642

The Curable Smoothie for Prevention and Treatment of Reye’s Syndrome Caused by Chicken Pox(Varicella-zoster virus)

Kyle J. Norton(Scholar, Master of Nutrients), all right reserved.
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.


The finding of a natural source for treatment of Reye’s Syndrome  has been running into many obstacles, many ingredients showed initially with promising result in animal studies have not produced same potentials in large sample size and mutli centers human trials.

 Reye’s Syndrome is a condition causes of  swelling of liver and brain, affecting mostly children often ages 4 to 12 and almost always associated with a previous viral infection such as influenza (flu), cold, or chicken pox(*).


Reye’s Syndrome caused by chicken pox
The smoothie for Prevention and Treatment of  Chickenpox(Varicella-zoster virus)
Yield: 2 servings (about 8 ounces each)
1/2 cup orange
1/2 cup sweet potato
1/2 tomato
1 cup rice milk

1. Place all ingredients in a blender and puree about 1 minute
2. Blend on high speed about 1 minute or until the mixture is thick and the ice is well crushed. Add more green tea drink if needed
3. Serve immediately

Recent studies by some renowned institutions suggested that orange(1), sweet potato(3) and tomato(5) may be the next generation of ingredient extracted from natural sources for reduced risk and treatment of Chicken Pox caused by Varicella-zoster virus.

Chickenpox is a infection infection caused by varicella zoster virus (VZV) of which can lead to extremely itchy blisters all over the body. The disease is is a highly contagious illness and one of the classic childhood diseases.
Herpes zoster or zona is defined as a viral disease with condition of a painful, blistering skin rash on one side of the body. Vitamin C, also known as L-ascorbate is a water soluble vitamin with a chemical structure formula of C6H6O6  found abundantly in orange may be effect for prevention and treatment of shingles.  According to the Heart-Jesus Hospital, Dernbach, intravenously administered ascorbic acid may have beneficial effects on herpes zoster-associated pain(1).

Dr. Schencking M and Dr. Kraft K. in the study of vitamin C against shingles suggested, combination of Cantharidin patches and intravenous administration of vitamin C is the best concomitant treatment of herpes zoster(2).

Vitamin E, found abundantly in sweet potato also exhibited anti human papillomavirus and herpes infections effect through decreased viral load and increased antiviral cytokine and peroxynitrite plasma levels(3).
According to the, vitamin E in the form of d, alpha-tocopherol acetate, in dose of 400 IU, 4 times a day, may be a highly effective therapy for patients with herpes zoster or zona(4).

Vitamin A, a bi-polar molecule formed by bonds between carbon and hydrogen and fat soluble vitamin, found abundantly in tomato is associated to patient with herpes zoster infections. Accoridng to the Wake Forest University School of Medicine, acute reductions in concentrations of plasma retinol (vitamin A) in patient with shingle may be related to existence of herpes zoster infection in recipients(5).

Taking altogether, The combination of Orange, Sweet Potato and Tomato may offer the potential effect not only in prevention of the onset and treatment of Chicken Pox caused by Varicella-zoster virus.
Children with increased risk of Chicken Pox  are wise to drink at least one serving daily. Children with Chicken Pox should drink the juice as much as they can, depending to the toleration of digestive system.


References
(*) Reye’s Syndrome (national Reye’s Syndrome association)
References
(1) Intravenous vitamin C in the treatment of shingles: results of a multicenter prospective cohort study. by Schencking M1, Vollbracht C, Weiss G, Lebert J, Biller A, Goyvaerts B, Kraft K.(PubMed)
(2) Cantharidin patches and intravenous administration of vitamin C in the concomitant treatment of herpes zoster: a case report by Schencking M1, Kraft K.(PubMed)
(3) Coenzyme Q(10), vitamin E, selenium, and methionine in the treatment of chronic recurrent viral mucocutaneous infections by De Luca C1, Kharaeva Z, Raskovic D, Pastore P, Luci A, Korkina L.(PubMed)
(4) Other treatments for herpes zoster neuralgia(PMC)
(5) Low plasma concentrations of retinol and alpha-tocopherol in hematopoietic stem cell transplant recipients: the effect of mucositis and the risk of infection by High KP1, Legault C, Sinclair JA, Cruz J, Hill K, Hurd DD.(PubMed)