The Best Smoothie of Blueberry, Tomato, Turmeric and Grape Juice for Prevention and Treatment of Neonatal Hepatitis

Kyle J. Norton(Scholar, Master of Nutrients), all right reserved.

Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.

Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post

Nominated for shorty award over last 4 years

Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

The smoothie for prevention and treatment of  Neonatal Hepatitis

Yield: 2 servings (about 8 ounces each)

3/4  cup blue berry
3/4 cup tomato
1 tsp curcumin

1 cup grape juice

1. Place all ingredients in a blender and puree about 1 minute

2. Blend on high speed about 1 minute or until the mixture is thick and the ice is well crushed.

3. Serve immediately

The finding of a natural source for treatment of   Neonatal Hepatitis has been running into many obstacles, many ingredients showed initially with promising result in animal studies have not produced same potentials in large sample size and mutli centers human trials.

Neonatal Hepatitis is a condition of liver inflammatory liver diseases occurred in the newborn, mostly within one to two months after birth. According to liver foundation anti viral infection together with intake of vitamin A, D and K should be helpful in fighting of free radicals in induction of oxidative stress(1).

Recent studies back by well known institutions proposed, Blueberry, Tomato, Turmeric and Grape Juice may be the next generation of natural ingredients for prevention and treatment of Neonatal Hepatitis.

Resveratrol is a phytochemical in the class of Stilbenoids, found abundantly in grape and blueberry may be a potent antioxidant for reduced risk and treatment of neonatal Hepatitis, through its anti viral infection(2). 

Accoridng to the IQ Institute of Infection and Immunity, resveratrol, the anti viral key molecules inhibited against HCV genotype 3a (GT3a) may offer an alternative attraction to target the viral helicase for treatment of hepatitis(3).

In a new human hepatoma cell line system for hepatitis C virus, the anioxidant effectively trigger autophagic cell death through the increased expression of autophagy through cell cycle arrest(4).

Turmeric is a perennial plant in the genus Curcuma, belongings to the family Zingiberaceae, native to tropical South Asia. The herb has been used in trditional medicine as anti-oxidant, hypoglycemic, colorant, antiseptic, wound healing agent, and to treat flatulence, bloating, and appetite loss, ulcers, eczema, inflammations, etc. Its phytochemical curcumin expressed anti hepatitis B virus (HBV) effect through inhibited HBV gene expression and replication(5).

According to the German Cancer Research Center (DKFZ), curcumin also reduced tumor incidence at other organ sites and suppressed formation of metastases and should be considered as a contra-indicated for patients suffering from inherited and acquired metal storage diseases that include patients with hepatitis C virus infection(6).

Curcuminoids, derived from the plant Curcuma domestica Val derivatives of curcumin, are effective in suppressing the hepatic microvascular inflammatory response against lipopolysacharide (LPS) through ameliorated expression of inflammatory cytokines(7).

Carotenoids, found abundantly in carrot and tomato also attenuated risk and treatment of neonatal hepatitis C through exhibition of synergistic effect(8). According to the Tongji Medical College, Huazhong University of Science and Technology, lutein, a member of carotenoids inhibited the activity of HBV through suppressed the secretion of HBsAg(antigen) from HepG2 2.2.15 cells in a dose-dependent manner(9).
Dr, Mawson AR and Dr. Steele TA., professors at the Des Moines University Osteopathic Medical Center, said, "The reduced rate of survival of liver grafts in patients with HBV infection could also be due to the continued presence of the virus, stimulated by retinoids in the graft tissue. "(10).

The effectiveness of Blueberry, Tomato, Turmeric and Grape Juice  may serve as cornerstones of pharmaceutical target for further studies in production of a potential medication for reduced risk, complications and treatment of Neonatal Hepatitis with little or no adverse effects.
Women who are at high risk of Neonatal Hepatitis due to family history, environment factors, .... should drink at least one serving daily and women with Neonatal Hepatitis should drink the smoothie as much as they can, depending to digestive toleration.
We don't recommend smoothie for newborn
Life style and dietary patter change are recommended.

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References
(1) How Is Neonatal Hepatitis Defined?(The liver disorder foundation)
(2) Identification of a resveratrol tetramer as a potent inhibitor of hepatitis C virus helicase by Lee S1, Yoon KD2, Lee M3, Cho Y3, Choi G3, Jang H4, Kim B5, Jung DH6, Oh JG2, Kim GW7, Oh JW7, Jeong YJ6, Kwon HJ5, Bae SK2, Min DH4, Windisch MP3,Heo TH2, Lee C1.(PubMed)
(3) Docking studies of Pakistani HCV NS3 helicase: a possible antiviral drug target. by Fatima K1, Mathew S2, Suhail M3, Ali A3, Damanhouri G3, Azhar E3, Qadri I3.(PubMed)
(4) Resveratrol arrests cell cycle and induces apoptosis in human hepatocellular carcinoma Huh-7 cells by Liao PC1, Ng LT, Lin LT, Richardson CD, Wang GH, Lin CC.(PubMed)
(5) Curcumin inhibits hepatitis B virus via down-regulation of the metabolic coactivator PGC-1alpha. by Rechtman MM1, Har-Noy O, Bar-Yishay I, Fishman S, Adamovich Y, Shaul Y, Halpern Z, Shlomai A.(PubMed)
(6) No prevention of liver and kidney tumors in Long-Evans Cinnamon rats by dietary curcumin, but inhibition at other sites and of metastases by Frank N1, Knauft J, Amelung F, Nair J, Wesch H, Bartsch H.(PubMed)
(7) Effect of curcuminoids as anti-inflammatory agents on the hepatic microvascular response to endotoxin by Lukita-Atmadja W1, Ito Y, Baker GL, McCuskey RS.(PubMed)
(8) Retinoids and rexinoids inhibit hepatitis C virus independently of retinoid receptor signaling by Murakami Y1, Fukasawa M2, Kaneko Y3, Suzuki T4, Wakita T5, Fukazawa H6.(PubMed)
(9) In vitro antiviral activity of lutein against hepatitis B virus by Pang R1, Tao JY, Zhang SL, Zhao L, Yue X, Wang YF, Ye P, Dong JH, Zhu Y, Wu JG.(PubMed)
(10) Possible role of retinoids in hepatitis B virus-associated liver damage By Mawson AR1, Steele TA.(PubMed)

Most Common Diseases of elder: Respiratory Disease: Benign lung tumors - Treatment In conventional medicine perspective

Kyle J. Norton(Scholar and Master of Nutrients)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

Respiratory Disease is defined as medical conditions which affect the breathing organ and tissues including Inflammatory lung disease, Obstructive lung diseases, Restrictive lung diseases, Respiratory tract infections, trachea, bronchi, bronchioles, alveoli, the nerves and muscles breathing , etc,.

Benign lung tumors, growth from many different structures in the lung, is defined as a conditions of abnormal cell growth with no tendency of spreading or masses that push normal cells out of the way rather than invading surrounding tissue restricted to a limited area in the lung. Approximately one out of 500 chest radiographs shows the incidental finding of a solitary pulmonary nodule and almost one half of these pulmonary lesions are caused by a tumor. Unfortunately, only 2% to 5% of alllung tumors are of benign origin, e. g. lipoma, fibroma, hamartoma, and chondroma, and the majority are malignant, most commonly primarylung cancer followed by metastases of extrapulmonary primary carcinomas. According to the study by Universitätsklinik für Pneumologie(a).

                             The Treatment

 In conventional medicine perspective
radiographs may be continued used to monitor the progression of lung nodules, if the tumor does not double in size in less than a year and it does not become cancerous. Other wise surgery may be the only option, but the aim of the surgery is to spare the lung, unless it is absolutely necessary for it to be removed and depending to the patients conditions.
1. Endoscopic cryotherapy
In a systematic review and evaluation of endoscopic cryotherapy of endobronchial tumors, investigating safety and efficacy, found that endoscopic cryotherapy was found to be a safe and useful procedure in the management of endobronchial tumors although its efficacy and appropriate indications have yet to be determined in well-designed controlled studies(29).

2. Bronchotomy
Less than 1% of lung neoplasms are represented by benign tumors. Among these, hamartomas are the most common with an incidence between 0.025% and 0.32%. According to the study by the University of Messina, bronchotomy or parenchimal resection through thoracotomy should be reserved only for cases where the hamatoma cannot be approached through endoscopy, or when irreversible lung functional impairment occurred after prolonged airflow obstruction. Generally, when endoscopic approach is used, this is through rigid bronchoscopy, laser photocoagulation or mechanical resection. Here we present a giant EH occasionally diagnosed and treated by fiberoptic bronchoscopy electrosurgical snaring(30).

3. Pulmonary segmentectomy
Pulmonary segmentectomy has been recognized as an operative option for complete resection of early-stage lung cancer in patients with poor pulmonary function. According to the study by, transbronchial indocyanine green injection into the relevant bronchus with the use of an infrared thoracoscope allows identification of intersegmental lines and planes during thoracoscopic segmentectomy(31).

4. Lobectomy
In the study to assess 14,473 patients who met our inclusion criteria, lobectomy conferred superior unadjusted overall (p < 0.0001) and cancer-specific (p = 0.0053) 5-year survival compared with segmentectomy. Even after adjusting for patient factors, tumor characteristics, and geographic location, we noted that patients who underwent lobectomy had superior overall and cancer-specific survival rates, regardless of tumor size(32).

5. Sleeve resection
There is a report of a 75-year-old man complained of sputum and was referred to our department. His sputum cytology was class III. Chest X-ray and computed tomography showed no abnormalities, but bronchoscopy revealed an elevated lesion in the membranous portion of the left main bronchus, which was pathologically diagnosed as squamous cell carcinoma in situ. Since bronchoscopy revealed no other lesions in the visible parts of the airway, it was considered to be a solitary, early lung cancer, and sleeve resection of the left main bronchus was performed(33).

6. Completion pneumonectomy (CP)
Completion pneumonectomy (CP) is a difficult operation in which the surgeon must use techniques such as intrapericardial ligation of the pulmonary vessels. There is a case of CP for a patient with recurrent lung cancer. A 63-year-old man was admitted to our hospital for evaluation of abnormal shadows in the right lung field in October 2002. Right middle lobectomy with mediastinal lymph node dissection had been performed in February 1993. Computed tomography (CT) revealed a hilar mass in the right upper lobe the day after admission. Bronchofiberscopic cytology revealed squamous cell carcinoma. Right completion pneumonectomy was performed on suspicion of metachronous multiple lung cancers 4 days later. Histopathologically, resected specimens represented adenosquamous carcinoma similar to the prior lesion from the middle lobe, and examination revealed that the tumor represented a recurrence following middle lobectomy. The patient remains well as of 19 months postoperatively(34).

7. Etc.


Chinese Food Therapy
The Best Way to prevent, treat your disease, including Obesity
and restore your health naturally with Chinese diet

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Super foods Library, Eat Yourself Healthy With The Best of the Best Nature Has to Offer

Sources
(a) http://www.ncbi.nlm.nih.gov/pubmed/22753285
(29) http://www.ncbi.nlm.nih.gov/pubmed/21716589
(30) http://www.ncbi.nlm.nih.gov/pubmed/21838930
(31) http://www.ncbi.nlm.nih.gov/pubmed/19952361
(32) http://www.ncbi.nlm.nih.gov/pubmed/21962268
(33) http://www.ncbi.nlm.nih.gov/pubmed/22510543
(34) http://www.ncbi.nlm.nih.gov/pubmed/15881232

Most common Diseases of 50plus: Heart Disease(The Articles) - The Chelation Therapy

Kyle J. Norton(Scholar and Master of Nutrients, all right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

                                  Heart Disease

Beside cancer, heart disease kills more than 2,000 Americans everyday. Approximately 60 million Americans have heart disease. There are many causes of heart disease. Anything that serves to damage the inner lining of blood vessels and impedes the transportation of oxygen and nutrition to the heart can be defined as a risk of heart disease.


Heart Diseases and Chelation Therapy

Heart diseases are caused by uncontrolled diets high in saturated and trans fats resulting in arteries being clogged up by bad cholesterol LDL and the inner lining of blood vessels being damaged impeding the transportation of oxygen and nutrition to the heart.

People with heart diseases using this type of therapy must be carefully selected and approved by their doctors. The prime candidate is people at their 40's and people already suffering from advanced forms of heart disease such as angina and intermittent claudication, because the people in this age group will experience some form of heart disease caused by excessive cholesterol intake and build up of calcium, scar tissues and fat within the arteries.

This form of chelation therapy includes the usage of an IV apparatus and EDTA that is a widely used abbreviation for the chemical compound ethylenediaminetetraacetic acid. EDTA, the chelation agent, not only helps to clean the harmful substances such as lead, uranium, nickel and calcium deposited in the arterial wall but also improves circulation, enhances the immune system and inhibits the creation of free radical. With the slow flow of EDTA from the bottle through the IV and finally into the patient's vein and bloodstream results in turning back the clock for many potential heart disease victims. Chelation therapy is not only helpful as an attractive alternative to bypass surgery, but also has the ability to improve the function of the brain, since this form of therapy is especially helpful in treating arterial blockage in the upper body.

Other benefits of chelation therapy include: reduction of liver-produced cholesterol, lowered cholesterol levels, reducing high blood pressure, and fewer excessive heart contractions.
With all the success in chelation therapy, it also produces some side effects for some people such as headaches, diarrhea, fainting, fatigues, fever, and cramps. Be sure you understand all these problems before taking chelation therapy.

Chinese Food Therapy
The Best Way to prevent, treat your disease, including Obesity
and restore your health naturally with Chinese diet

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Super foods Library, Eat Yourself Healthy With The Best of the Best Nature Has to Offer

Herbal therapy: Popular Herbal Feverfew (Tanacetum Parthenium)

Kyle J. Norton(Scholar and Master of Nutrients, all right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

                     Feverfew 

Feverfew is a small bush with scene leaves, genus Tanacetum, belonging to family Asteraceae and native to Euro-Asia. The heral plant has been used in traditional and herbal medicine to treat fever, headaches, migraine headaches, arthritis, stomach aches, toothaches, insect bites, infertility, problems with menstruation and labor during childbirth etc.

Health benefits
1. Migraine headaches
In the evaluation of Feverfew's effectiveness in treating migraine headaches over thousand of year in herbal medicine, research found that sublingual feverfew/ginger appears safe and effective as a first-line abortive treatment for a population of migraineurs who frequently experience mild headache prior to the onset of moderate to severe headache. Feverfew/ginger was generally well tolerated with oral numbness and nausea being the most frequently occurring adverse event, according to "A double-blind placebo-controlled pilot study of sublingualfeverfew and ginger (LipiGesic™ M) in the treatment of migraine" by Cady RK, Goldstein J, Nett R, Mitchell R, Beach ME, Browning R.(1)

2. Anti cancers
In the investigation of The medicinal herb feverfew [Tanacetum parthenium (L.) Schultz-Bip.] effectiveness in treating against tumor, and inflammatory properties found that apigenin and luteolin might have moderate to weak synergistic effects with parthenolide on the inhibition of cancer cell growth of Hs605T, MCF-7, and SiHa, according to "Antiproliferative activities of parthenolide and goldenfeverfew extract against three human cancer cell lines" by Wu C, Chen F, Rushing JW, Wang X, Kim HJ, Huang G, Haley-Zitlin V, He G.(2)

3. Anti-inflammatory activity
In the assessment of a parthenolide-depleted extract of Feverfew (PD-Feverfew) and to determine its effectiveness as an anti-inflammatory agent found that PD-Feverfew extracts have potent anti-inflammatory activity suggesting that this botanical would be efficacious in relieving inflammation without inducing immune sensitization, according to "Anti-inflammatory activity of parthenolide-depletedFeverfew (Tanacetum parthenium)" by Sur R, Martin K, Liebel F, Lyte P, Shapiro S, Southall M.(3)

4. Skin protective agent
In the determination of Feverfew antioxidants and their effect in protecting skin from UV irradiation and external aggression found that through the ability to scavenge free radicals, preserve endogenous antioxidant levels, reduce DNA damage and induce DNA repair enzymes, which can help repair damaged DNA, parthenolide-depleted extract of Feverfew may protect skin from the numerous external aggressions encountered daily by the skin and reduce the damage to oxidatively challenged skin, according to "Parthenolide-depleted Feverfew(Tanacetum parthenium) protects skin from UV irradiation and external aggression" by Martin K, Sur R, Liebel F, Tierney N, Lyte P, Garay M, Oddos T, Anthonavage M, Shapiro S, Southall M.(4)

5. Blood platelet aggregation
In the research of extracts of feverfew and parthenolide and theirs effect on blood platelet aggregation in-vitro found that Both feverfew extract and parthenolide were more effective as inhibitors of the [14C]5-HT secretion and aggregation induced by some agents and not others, and were most effective as inhibitors of the [14C]5-HT secretion (but not the aggregation) induced by PMA. This suggests that the effects of feverfew/parthenolide on the protein kinase C pathway warrants further study, according to "A comparison of the effects of an extract of feverfew and parthenolide, a component of feverfew, on human platelet activity in-vitro" by Groenewegen WA, Heptinstall S.(5)

5. Antiserotonergic activity
In the comparison of the extracts of Tanacetum parthenium (Feverfew) and parthenolide and to determine theirs 5-Hydroxytryptamine-inhibiting activity found that the extract when degraded thermally upto 10% could significantly block the 5-HT receptors and neuronal release of 5-HT, however, on further degradation it lost its inhibitory capacity markedly. Similar results were observed in rats fed orally with undergraded and degraded Feverfew powder and injected i.p. with parthenolide. Feverfew powder was more effective than any of its extracts or pure parthenolide, according to "5-Hydroxytryptamine-inhibiting property ofFeverfew: role of parthenolide content" by Mittra S, Datta A, Singh SK, Singh A.(6)

6. Antibacterial activity
In the determination of Feverfew (Tanacetum parthenium L.) (Asteraceae), a medicinal plant traditionally and its essential oil antibacterial effectiveness found that the oil of Ardahan sample showed the highest activity on S. aureus (125 microg/mL) which is likewise two fold concentration of the positive control chloramphenicol (62.5 microg/mL). DPPH scavenging activity was 59.3% of the oil from Davutpasa at 15 mg/mL concentration. When compared to positive control alpha-tocopherol (94.6%) Savşat oil (28.2%) showed low and Davutpasa oil showed medium DPPH scavenging activity. All of the oils showed toxicity to Vibrio fischeri in the TLC-bioluminescence assay, according to "Antibacterial activity and the variation of Tanacetum parthenium (L.) Schultz Bip. essential oils from Turkey" by Polatoglu K, Demirci F, Demirci B, Gören N, Başer KH.(7)

8. Skin cancer
In the evaluation of Parthenolide, an active component of feverfew (Tanacetum parthenium) and it inhibits proliferation and kills various cancer cells found that the melanoma cells from vertical growth phase and melanocytes were less susceptible to parthenolide-induced cell death than metastatic cells when drug concentration was at least 6 mumol/l. Reactive oxygen species level was not significantly increased in melanoma cells. However, preincubation of parthenolide with the thiol nucleophile N-acetyl-cysteine protected melanoma cells from parthenolide-induced cell death suggesting the reaction with intracellular thiols as the mechanism responsible for parthenolide activity. In conclusion, the observed anticancer activity makes parthenolide an attractive drug candidate for further testing in melanoma therapy, according to "Parthenolide, a sesquiterpene lactone from the medical herb feverfew, shows anticancer activity against human melanoma cells in vitro" by Lesiak K, Koprowska K, Zalesna I, Nejc D, Düchler M, Czyz M.(8)

9. Apigenin and luteolin
In the classification of the medicinal herb feverfew [Tanacetum parthenium (L.) Schultz-Bip.] and its parthenolide, a sesquiterpene lactone on anti-migraine, anti-tumor, and anti-inflammatory properties found that feverfew ethanolic extract inhibited the growth of all three types of cancer cells with a half-effective concentration (EC50) of 1.5 mg/mL against Hs605T, 2.1 mg/mL against MCF-7, and 0.6 mg/mL against SiHa as a result of its components apigenin and luteolin, according to "Antiproliferative activities of parthenolide and golden feverfewextract against three human cancer cell lines" by Wu C, Chen F, Rushing JW, Wang X, Kim HJ, Huang G, Haley-Zitlin V, He G.(9)

10. Antioxidants
In the investigation of the constant exposure of the skin to oxidative stress results in damage to cellular DNA and cell membrane lipids and proteins found that soy,feverfew, mushroom extracts, teas, Coffea arabica (CoffeeBerry), Pinus pinaster (Pycnogenol), and Polypodium leucotomos have promising efficacy in the topical treatment of oxidative stress-induced dermatoses, according to "Naturalantioxidants" by Berson DS.(10)

11. Colorectal cancer
In the research of Parthenolide, the main components of Feverfew and itsapoptosis effect in cancer cells found that Parthenolide rapidly depleted intracellular thiols, including both free glutathione (GSH) and protein thiols. Concomitantly, there were dose- and time-dependent increases in intracellular reactive oxygen species (ROS) and calcium levels. Increased expression of GRP78 protein, a marker for endoplasmic reticulum stress was also detected. All these changes preceded parthenolide-induced apoptotic cell death, according to "Critical roles of intracellular thiols and calcium in parthenolide-induced apoptosis in human colorectal cancer cells" by Zhang S, Ong CN, Shen HM.(11)

12. Antithrombotic effect
In the investigation of The effects of an extract of the plant feverfew on the interaction of platelets with surfaces coated with human collagens of type III and IV (CIII, CIV), and on the integrity of the endothelial cell (EC) monolayer found that that feverfew may have antithrombotic potential in addition to its claimed benefit in fever, migraine and arthritis, according to "Feverfew--an antithrombotic drug?" by Loesche W, Mazurov AV, Voyno-Yasenetskaya TA, Groenewegen WA, Heptinstall S, Repin VS.(12)

13.
In the demonstration of the inhibitory effect on inflammatory cytokines and matrix metalloproteinase production from stimulated synovial cells derived from rheumatoid arthritis patients found that Parthenolide is one of the main sesquiterpense lactones responsible for the bioactivities of feverfew and recently reported to inhibit NFkappaB activation. Parthenolide has ameliorated the severity of joint destruction in experimental animal model. Based upon these findings, NFkappaB may be one of important therapeutic target for arthritis, according to "[Application of NFkappaB inhibitor for arthritis].[Article in Japanese]" by Tomita T, Kunugiza Y, Nomura K, Morimoto D, Kuroda S, Yoshikawa H.(13)

14. Etc.

Side effects
1. Feverfew may interact with other medicine. If you are taking blood thin medicine, please consult with your doctor, according to "Herbal medicinals: selected clinical considerations focusing on known or potential drug-herb interactions" by Miller LG.(a)
2. Do not take the herb, if you are pregnant or breast feeding with out approval of related field specialist.
3. Over doses can cause abdominal pain, indigestion, gas, diarrhea, nausea, vomiting, and nervousness.
4. Feverfew may cause allergic effect to some people with allergies to chamomile, ragweed.
5. Etc.

Chinese Food Therapy
The Best Way to prevent, treat your disease, including Obesity
and restore your health naturally with Chinese diet

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Super foods Library, Eat Yourself Healthy With The Best of the Best Nature Has to Offer

Sources
(a) http://www.ncbi.nlm.nih.gov/pubmed/9818800
(1) http://www.ncbi.nlm.nih.gov/pubmed/21631494
(2) http://www.ncbi.nlm.nih.gov/pubmed/16579729
(3) http://www.ncbi.nlm.nih.gov/pubmed/19112586
(4) http://www.ncbi.nlm.nih.gov/pubmed/18071724
(5) http://www.ncbi.nlm.nih.gov/pubmed/1981582
(6) http://www.ncbi.nlm.nih.gov/pubmed/11603284
(7) http://www.ncbi.nlm.nih.gov/pubmed/20299764
(8) http://www.ncbi.nlm.nih.gov/pubmed/19949351
(9) http://www.ncbi.nlm.nih.gov/pubmed/16579729
(10) http://www.ncbi.nlm.nih.gov/pubmed/18681153
(11) http://www.ncbi.nlm.nih.gov/pubmed/15142672
(12) http://www.ncbi.nlm.nih.gov/pubmed/2459017
(13) http://www.ncbi.nlm.nih.gov/pubmed/19404004

Most common Diseases of 50plus: Heart Disease(The Articles) - Fat: Friend or Foe?

Kyle J. Norton(Scholar and Master of Nutrients, all right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

                                  Heart Disease

Beside cancer, heart disease kills more than 2,000 Americans everyday. Approximately 60 million Americans have heart disease. There are many causes of heart disease. Anything that serves to damage the inner lining of blood vessels and impedes the transportation of oxygen and nutrition to the heart can be defined as a risk of heart disease.


Heart Diseases- Dairy Products: Friend Or Foe?

 There are many opinions about pros and cons of dairy products in our diet. Would it also be the cause of cholesterol building up in the arteries, high blood pressure and heart diseases? In this article, we will discuss dairy products: friend or foe?

Diary products which contain lactose are products made from milk including cheese, yogurt, and butter that have been part of the human diet for years. They play an important role in a healthy diet, both for nutritional value and personal enjoyment but also contains elements that can cause cholesterol to build up in the arteries and high blood pressure resulting in heart diseases.
Study shows that milk drinkers are no more likely to die of a heart disease than non milk drinkers. In fact drinking less than 4 cups of milk a day actually lessens the chance of dying of any cause.
Since milk contains high saturated fat, by selecting skim or low fat milk it not only helps to lessen the chance of heart attack but also benefits from the nutritional supplements and minerals contained in milk.
Other dairy products that we would like to mention here are eggs. Eggs get a bad name for high cholesterol content. Study shows that eating one egg a day does not increase the risk of heart attack or stroke, unless you are diabetic. Eggs contain high amounts of B vitamins, vitamin A, D, and E that are vital for a healthy heart.
Besides milk and eggs, there are other dairy products such as cheese and butter. Statistics show that North Americans eat nearly 3 times more cheese than they did 30 years ago. Cheese contains high amounts of calcium but also high amounts in saturated fat which is the main cause of cholesterol build up in the arteries, and high blood pressure resulting in heart diseases and stroke. In fact if you can cut the amount of cheese and butter consumed daily by half and replace them with low fat cheese you will limit your risk of heart attack. For best protection, be sure to limit your cheese intake to less than 2 ounces a week.
By all means, choosing low fat and limiting your daily intake of dairy products will not only limit the risk of heart disease but also help your body to absorb the needed nutrition as result of better health.

Chinese Food Therapy
The Best Way to prevent, treat your disease, including Obesity
and restore your health naturally with Chinese diet

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Super foods Library, Eat Yourself Healthy With The Best of the Best Nature Has to Offer

The Holistic prevention, management and treatment of Polycystic Ovarian Syndrome: The Vitamins

Kyle J. Norton(Scholar, Master of Nutrients), all right reserved.
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

Polycystic Ovarian Syndrome

Polycystic Ovarian Syndrome is defined as endocrinologic diseases among reproductive-age women caused by undeveloped follicles clumping on the ovaries that interferes with the function of the normal ovaries associated with a high risk for metabolic disorder(1) as resulting of enlarged ovaries(2), leading to hormone imbalance(excessive androgen and anti-müllerian hormone (AMH) )(1)(3)(4)(5), induced Hirsutism(6)(7), reproductive disorder(10(12)), risks of type 2 diabetes(9)(10)(11), metabolic syndrome(10)(12) and early cardiovascular disease(8)(13), acne(10)(14), endometrial cancer(18)(19),weight gain and obesity(15)(16)(17). The syndrome effects over 5% of women population or 1 in 20 women.
Unfortunately, according to studies, women with PCOs after the reproductive age, are associated to continuously increase risk of type II diabetes, with no increasingaltered glucose tolerance(20), CVD and hypertension(21).

The prevention and management

Polycystic ovary syndrome (PCOS) is unpreventable in Western medicine. Early diagnosis and treatment may reduce risk of its complications, including infertility, metabolic syndrome, obesity, diabetes, cardiovascular diseases, stroke, etc.

Although PCOS cannot be completely avoided, strengthening immunity has shown a significant reduction of chronic inflammatory diseases(266)(267)(268).

The Vitamins

1. Vitamin B2
Vitamin B2 required for a wide variety of cellular processes, plays a key role in energy metabolism, enhances the digestive system in absorbing nutrients and supports the immune system(285)(286)(287)in fighting against irregular cell growth causes of chronic inflammatory disease(288).

2. Vitamin C
Vitamin C, a water-soluble vitamin and an antioxidant found in high concentrations in immune cells, is not only important in aiding the digestive system in absorbing nutrients, but also enhances the production of white blood cell(289)(290) of the immune system in protection of the body against oxidative stress, harmful bacteria(291) and virus induced inflammation.

3. Vitamin A
Retinoic acid, appears to maintain normal skin health by switching on genes and differentiating keratinocytes (immature skin cells)(292) into mature epidermal cells and helps to detoxify liver(293), and enhances the immune system(294)(295) in protecting our body through its anti tumor functions (296).

4. Vitamin E
Vitamin E is fat-soluble compounds included both tocopherols and tocotrienols. It besides is an polyphenol antioxidants(296)(297)(302) in scavenging free radicals, but also promotes the immune system in enhanced functions of B-cells(298)(299)(300), the immune cells(301)(303) in production of antibodies to destroy irregular cell proliferation.

5. Vitamin D
15 minutes in the the Sun daily has shown to provide necessary vitamin D for the body. Over 68% of women with PCOs had vitamin D deficiency.(304). According to Medical faculty of P.J.Šafarik University Košice, women with vitamin D deficient PCOs are exhibited a significantly higher body mass index (BMI), fasting insulin, and homeostasis model assessment-insulin resistance and borderline higher glycemia in comparison to controls(305).

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References
(1) Adiposity and metabolic dysfunction in polycystic ovary syndrome by Sam S.(PubMed)
(2) A "kiss" before conception: triggering ovulation with kisspeptin-54 may improve IVF by Young SL.(PubMed)
(3.) Androgen hyperfunction and excessive heterosexual hair growth in women, with special attention to the polycystic ovarian syndrome by Lunde O1.(PubMed)
(4) Expression of anti-Müllerian hormone in letrozole rat model of polycystic ovary syndrome by Du DF1, Li XL, Fang F, Du MR.(PubMed)
(5) [Serum levels of anti-muller hormone in women with polycystic ovary syndromeand healthy women of reproductive age].[Article in Bulgarian] by Parahuleva N, Pehlivanov B, Orbecova M, Deneva T, Uchikova E.(PubMed)
(6) [Current opinions on the etiology and pathophysiology of hirsutism].[Article in Polish] by Krysiak R1, Kedzia A, Okopień B.(PubMed)
(7) The clinical evaluation of hirsutism by Somani N1, Harrison S, Bergfeld WF.(PubMed)
(8) Polycystic ovary syndrome and insulin: our understanding in the past, present and future by Mayer SB1, Evans WS, Nestler JE.(PubMed)
(9) Association of mean platelet volume with androgens and insulin resistance in nonobese patients with polycystic ovary syndrome by Dogan BA1, Arduc A2, Tuna MM1, Karakılıc E1, Dagdelen I1, Tutuncu Y1, Berker D1, Guler S1.(PubMed)
(10) Approach to the patient: contraception in women with polycystic ovary syndrome by Yildiz BO1.(PubMed)
(11) Polycystic ovarian syndrome (PCOS): a significant contributor to the overall burden of type 2 diabetes in women by Talbott EO1, Zborowski JV, Rager JR, Kip KE, Xu X, Orchard TJ.(PubMed)
(12) Prevalence of vitamin D deficiency in Slovak women with polycystic ovary syndrome and its relation to metabolic and reproductive abnormalities by Figurová J1, Dravecká I, Javorský M, Petríková J, Lazúrová I.(PubMed)
(13) Role of Insulin Sensitizers on Cardiovascular Risk Factors in Polycystic Ovarian Syndrome: A Meta-Analysis by Thethi TK1, Katalenich B2, Nagireddy P3, Chabbra P4, Kuhadiya N5, Fonseca V1.(PubMed)
(14) Acne in hirsute women by Lumezi BG1, Pupovci HL1, Berisha VL1, Goçi AU2, Gerqari A3.(PubMed)
(15) Obesity and polycystic ovary syndrome by Naderpoor N1, Shorakae S, Joham A, Boyle J, De Courten B, Teede HJ.(PubMed)
(16) Polycystic ovary syndrome: a complex condition with psychological, reproductive and metabolic manifestations that impacts on health across the lifespan by Teede H1, Deeks A, Moran L.(PubMed)
(17) Metabolic Evidence of Diminished Lipid Oxidation in Women With Polycystic Ovary Syndrome. by Whigham LD1, Butz DE2, Dashti H3, Tonelli M3, Johnson LK1, Cook ME2, Porter WP4, Eghbalnia HR5, Markley JL6, Lindheim SR7, Schoeller DA8, Abbott DH9, Assadi-Porter FM10.(PubMed)
(18) Risk of endometrial, ovarian and breast cancer in women with polycystic ovary syndrome: a systematic review and meta-analysis by Barry JA1, Azizia MM1, Hardiman PJ2.(PubMed)
(19) Risk of cancer among women with polycystic ovary syndrome: a Danish cohort study by Gottschau M1, Kjaer SK2, Jensen A1, Munk C1, Mellemkjaer L3.(PubMed)
(20) Polycystic ovary syndrome: metabolic consequences and long-term management by Carmina E1.(PubMed)
(21) Arterial stiffness is increased in asymptomatic nondiabetic postmenopausal women with a polycystic ovary syndrome phenotype by Armeni E1, Stamatelopoulos K, Rizos D, Georgiopoulos G, Kazani M, Kazani A, Kolyviras A, Stellos K, Panoulis K, Alexandrou A, Creatsa M, Papamichael C, Lambrinoudaki I.(PubMed)
(266) [Immunopathological responses in women with chronic inflammatorydiseases of the uterus and appendages and their therapeutic correction].[Article in Russian] by Medvedev BI1, Kazachkova EA, Kazachkov EL.(PubMed)
(267) Cross Talk Between ER Stress, Oxidative Stress, and Inflammation in Health and Disease by Dandekar A1, Mendez R, Zhang K.(PubMed)
(268) New dog and new tricks: evolving roles for IL-33 in type 2 immunity by Lott JM1, Sumpter TL1, Turnquist HR2.(PubMed)
(285) Food, Immunity, and the Microbiome by Tilg H1, Moschen AR2.(PubMed)

(286) Edible mushrooms: improving human health and promoting quality life by Valverde ME1, Hernández-Pérez T1, Paredes-López O1.(PubMed)

(287) [Effect of some vitamins on activity of immunocompetent cells].[Article in Russian]by Nezgovorov DV.(PubMed)

(288) Antioxidants keep the potentially probiotic but highly oxygen-sensitive human gut bacterium Faecalibacterium prausnitzii alive at ambient air by Khan MT1, van Dijl JM1, Harmsen HJ1.(PubMed)

(289) Storing red blood cells with vitamin C and N-acetylcysteine prevents oxidative stress-related lesions: a metabolomics overview by Pallotta V1, Gevi F1, D'alessandro A1, Zolla L1.(PubMed)

(290) Red blood cell metabolism under prolonged anaerobic storage by D'Alessandro A1, Gevi F, Zolla L.(PubMed)

(291) Alterations in antioxidant defense system of workers chronically exposed to arsenic, cadmium and mercury from coal flying ash by Zeneli L1, Sekovanić A, Ajvazi M, Kurti L, Daci N.(PubMed)

(292) Indomethacin-induced translocation of bacteria across enteric epithelia is reactive oxygen species-dependent and reduced by vitamin C by Schoultz I1, McKay CM, Graepel R, Phan VC, Wang A, Söderholm J, McKay DM.(PubMed)

(293) Vitamin C derivative ascorbyl palmitate promotes ultraviolet-B-induced lipid peroxidation and cytotoxicity in keratinocytes by Meves A1, Stock SN, Beyerle A, Pittelkow MR, Peus D.(PubMed)

(294). Effects of dried fish on antioxidant levels in rat liver by Anilakumar KR1, Khanum F, Krishna KR, Viswanathan KR.(PubMed)

(295) Vitamin A and retinoic acid in T cell-related immunity by Ross AC1.(PubMed)

(296) Vitamin A and immune regulation: role of retinoic acid in gut-associated dendritic cell education, immune protection and tolerance by Cassani B1, Villablanca EJ, De Calisto J, Wang S, Mora JR.(PubMed)

(297) Modulatory role of vitamin A on the Candida albicans-induced immune response in human monocytes by Klassert TE1, Hanisch A, Bräuer J, Klaile E, Heyl KA, Mansour MK, Tam JM, Vyas JM, Slevogt H.(PubMed)
(298) [Toxicology of the synthetic antioxidants BHA and BHT in comparison with the natural antioxidant vitamin E].[Article in German]by Kahl R1, Kappus H.(PubMed)
(299) Effectiveness of antioxidants (vitamin C and E) with and without sunscreens as topical photoprotectants by Darr D1, Dunston S, Faust H, Pinnell S.(PubMed)
(300) Immune dysfunction and cytokine production in hemodialysis. Could they be lessened by vitamin E-coated dialyzer membrane by Senatore M, Cecere P, Colombo P, Costantini L, Filiberti O, Piccini G, Peona C, Buemi M, Nicoletti A, Rizzuto G.(PubMed)
(301) Prospective crossover trial of the influence of vitamin E-coated dialyzer membranes on T-cell activation and cytokine induction by Girndt M1, Lengler S, Kaul H, Sester U, Sester M, Köhler H.(PubMed)
(302) Vitamin E and immunity by Moriguchi S1, Muraga M.(PubMed)
(303) The role of vitamin E in T-cell differentiation and the decrease of cellularimmunity with aging.by Moriguchi S1.(PubMed)
(304) Evaluation of Relation between Anthropometric Indices and Vitamin D Concentrations in Women with Polycystic Ovarian Syndrome by Faraji R1, Sharami SH1, Zahiri Z1, Asgharni M1, Kazemnejad E1, Sadeghi S1.(PubMed)
(305) Prevalence of vitamin D deficiency in Slovak women with polycystic ovary syndrome and its relation to metabolic and reproductive abnormalities by Figurová J1, Dravecká I, Javorský M, Petríková J, Lazúrová I.(PubMed

The Curable Smoothie for Prevention and Treatment of Reye’s Syndrome Caused by influenza virus

Kyle J. Norton(Scholar, Master of Nutrients), all right reserved.

Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.

Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post

Nominated for shorty award over last 4 years

Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

The finding of a natural source for treatment of Reye’s Syndrome  has been running into many obstacles, many ingredients showed initially with promising result in animal studies have not produced same potentials in large sample size and mutli centers human trials.

 Reye’s Syndrome is a condition causes of  swelling of liver and brain, affecting mostly children often ages 4 to 12 and almost always associated with a previous viral infection such as influenza (flu), cold, or chicken pox(*).


Reye’s Syndrome caused by  influenza virus
The smoothie for reduced risk and treatment of influenza virus
Yield: 2 servings (about 8 ounces each)
1 1/2 cups grapes
1 cup green tea drink (Make from 4 grams(2 tea bags) of green tea, a slice of ginger and a cup of hot water lipped for 5 minutes, and set aside for cooling to room temperature)

1. Place all ingredients in a blender and puree about 1 minute
2. Blend on high speed about 1 minute or until the mixture is thick and the ice is well crushed.
3. Serve immediately

The finding of a natural source for reduced risk and treatment of influenza virus has encountered many obstacles, many ingredients showed initially promising result in animal studies have not produced same potentials in either large sample size and mutli centers human trials.

Scientists in some well known institutions may have found the therapeutic and potential ingredients from natural sources(Green tea and grape) for reduced risk and treatment of influenza.

Green tea has been a precious drink in traditional Chinese culture and used exceptional in socialization for more than 4000 thousand years. Because of their health benefits, they have been cultivated for commercial purposes all over the world.In animal model, polyphenolic compounds present in green tea, particularly catechins, are well known to process a strong anti-influenza activity in in a dose-dependent effect, especially in the early phase of lungs infection(1).

According to the Yonsei University, Catechin derivatives found in green tea also exhibited a broad spectrum activity against various subtypes of influenza viruses, through its antioxidant effect in inhibition of circulating human influenza viruses (A/H1N1, A/H3N2 and B type), H2N2 and H9N2 avian influenza virus, the viruses on red blood cell (RBC)(2).
Dr. Song JM and colleagues at the Yonsei University, polyphenolic compound catechins ((-)-epigallocatechin gallate (EGCG), (-)-epicatechin gallate (ECG) and (-)-epigallocatechin (EGC)) all showed to exhibited antiviral effect on influenza virus through altering the physical properties of viral membrane(3).

Grape is a woody vines of the genus Vitis, belong to the family Vitaceae, native to southern Turkey.
Its antioxidant, resveratrol has shown to process strong anti influenza virus, including, inhibitory effect on the NA activity of the influenza virus strain A/PR/8/34 (H1N1)(4)(5), epidemiological studies suggest.

Resveratrol (RV) in the Univ. of Rome Sapienza study also exhibits anti-inflammatory, and anti-proliferative properties against a wide variety of viruses including members of the Herpesviridae family, retroviruses, influenza A virus and polyomavirus by altering certain cellular pathways(6).

Dr. Thapa M and colleagues at the Kansas State University said, " polyphenols, such as resveratrol and epigallocatechin gallate (EGCG), showed significant anti-influenza activity in vitro and/or in vivo", especially against influenza virus (porcine H1N1 strain)(7).

Taking altogether people who are at increased risk of influenza due to weaken immunity and aging .....should drink at least one serving daily and people with influenza should drink the smoothie at 4 servings a day, depending to digestive toleration.

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References

(*0 (1) Reye’s Syndrome (national Reye’s Syndrome association)
(1) Anti-influenza virus activity of green tea by-products in vitro and efficacy against influenza virus infection in chickens by Lee HJ1, Lee YN, Youn HN, Lee DH, Kwak JH, Seong BL, Lee JB, Park SY, Choi IS, Song CS.(PubMed)
(2) Biological evaluation of anti-influenza viral activity of semi-synthetic catechin derivatives by Song JM1, Park KD, Lee KH, Byun YH, Park JH, Kim SH, Kim JH, Seong BL.(PubMed)
(3) Antiviral effect of catechins in green tea on influenza virus by Song JM1, Lee KH, Seong BL.(PubMed)
(4) In vitro antiviral effects and 3D QSAR study of resveratrol derivatives as potent inhibitors of influenza H1N1 neuraminidase by Li C1, Fang JS, Lian WW, Pang XC, Liu AL, Du GH.(PubMed)
(5) [Active neuraminidase constituents of Polygonum cuspidatum against influenza A(H1N1) influenza virus].[Article in Chinese] by Chen KT1, Zhou WL, Liu JW, Zu M, He ZN, Du GH, Chen WW, Liu AL.(PubMed)
(6) Resveratrol inhibits Epstein Barr Virus lytic cycle in Burkitt's lymphoma cells by affecting multiple molecular targets by De Leo A1, Arena G, Lacanna E, Oliviero G, Colavita F, Mattia E.(PubMed)
(7) Synthesis and antiviral activity of substituted quercetins by Thapa M1, Kim Y, Desper J, Chang KO, Hua DH.(PubMed)