Wednesday, June 8, 2016

The Best of Tomato, Brazil Nut and Grape Juice for Prevention and Treatment of HIV/AIDS and Pregnancy

Kyle J. Norton(Scholar, Master of Nutrients), all right reserved.
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

The Incredible and Effective smoothie for Reduced Risk and treatment of HIV/AIDS and Pregnancy

Yield: 2 serving (about 8 ounce each)
3/4 cup tomatoes
3/4 cup Brazil nut
1 cup organic grape juice

1. Place all ingredients in a blender and puree about 1 minute
2. Blend on high speed about 1 minute or until the mixture is thick and the ice is well crushed.
3. Serve immediately

Human immunodeficiency virus (HIV) is a lentivirus that causes acquired immune deficiency syndrome (AIDS) of which can lead to the progression of weakened immune system causes of infectious diseases and cancers.

The finding of a natural source for reduced risk and treatment of HIV/AIDS and Pregnancy has been running into many obstacles, many ingredients showed initially with promising result in animal studies have not produced same potentials in either large sample size and mutli centers human trials.

Strong evidences of number of renowned institutions suggested that natural sources, including carotenoids from tomatoes, selenium from brazil nut  may be a combination ingredients for reduced risk and treatment of HIV/AIDS and Pregnancy through their effects in improvement in immunological parameters and decreased evidence of lipid peroxidation(1).

Carotenoids, group of phytochemicals found abundantly in tomato which is a red, edible fruit, genus Solanum, belongings to family Solanaceae, native to South America. Because of its health benefits, tomato is grown world wide for commercial purpose and often in green house.
Dr. Irlam JH and colleagues at the study of micronutrient supplementation in children and adults with HIV infection said, " Vitamin A alone reduced all-cause mortality and improved growth in a small sub-group of HIV-infected children in one hospital-based trial, and reduced diarrhoea-associated morbidity in a small HIV-infected sub-group of infants in another trial"(2).
Importantly, according to the University of Cape Town, in the guideline of World Health Organization (WHO) recommendations in promoted and supported adequate dietary intake of micronutrients in HIV/AIDS and Pregnancy, suggested that multiple micronutrient supplements, including vitamin A and selenium conferred multiple clinical benefits to pregnant women and their offspring(3).

Resveratrol is a phytochemical in the class of Stilbenoids, found abundantly in peanut, grape and blueberry. Recent study suggested that Resveratrol reduced viral replication by 20% to 30%. With almost 12% of the world population suffering from HIV/AIDS(5).
Dr. Singh  and DrPai RS in the study of immune system inHIV/AIDS patients
said " antioxidants might have a significant role in the treatment of HIV/AIDS. An additional approach to treating HIV infection is fortifying the immune response of infected people. Immune modulators help to activate and boost the normal immune function. The present review first describes the boon of antioxidants (especially Vitamin A) and immune modulators (cytolin, resveratrol, murabutide, setarud, tucaresol, AVR118, Immunitin (HE2000), reticulose, and interleukin-7) in the treatment of HIV/AIDS"(4).

The identification of ingredient of Tomato, Brazil Nut and Grape Juice may serve as a foundation for establish a potential and natural source for reduced early onset and treatment of HIV/AIDS and Pregnancy in sometime in the future.
Women who are at increased risk of HIV/AIDS and Pregnancy due to family history and sexual active should drink at least 2 servings a day and people with HIV/AIDS and Pregnancy should drink as much as they can, depending to the digestive toleration. Change of life style and dietary pattern are recommended.

All Forms of Arthritis are Curable

Ovarian Cysts And PCOS Elimination




References
(1) Nutrients and HIV: part one -- beta carotene and selenium by Patrick L.(PubMed)
(2) Micronutrient supplementation in children and adults with HIV infection by Irlam JH1, Visser ME, Rollins N, Siegfried N.(PubMed)
(3) Micronutrient supplementation in pregnant women with HIV infection by Siegfried N1, Irlam JH, Visser ME, Rollins NN.(PubMed)
(4) Dawn of antioxidants and immune modulators to stop HIV-progression and boost the immune system in HIV/AIDS patients: An updated comprehensive and critical review. by Singh G1, Pai RS2.(PubMed)
(5) Recent advances of resveratrol in nanostructured based delivery systems and in the management of HIV/AIDS. by Singh G1, Pai RS2.(PubMed)

Most Common Diseases of elder: Respiratory Disease: Benign lung tumors - Treatment In herbal medicine perspective

Kyle J. Norton(Scholar and Master of Nutrients)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

Respiratory Disease is defined as medical conditions which affect the breathing organ and tissues including Inflammatory lung disease, Obstructive lung diseases, Restrictive lung diseases, Respiratory tract infections, trachea, bronchi, bronchioles, alveoli, the nerves and muscles breathing , etc,.

Benign lung tumors, growth from many different structures in the lung, is defined as a conditions of abnormal cell growth with no tendency of spreading or masses that push normal cells out of the way rather than invading surrounding tissue restricted to a limited area in the lung. Approximately one out of 500 chest radiographs shows the incidental finding of a solitary pulmonary nodule and almost one half of these pulmonary lesions are caused by a tumor. Unfortunately, only 2% to 5% of alllung tumors are of benign origin, e. g. lipoma, fibroma, hamartoma, and chondroma, and the majority are malignant, most commonly primarylung cancer followed by metastases of extrapulmonary primary carcinomas. According to the study by Universitätsklinik für Pneumologie(a).

                      The Treatment


In herbal medicine perspective
1. Roots of Prismatomeris connata
The roots of Prismatomeris connata have been used in traditional herbal medicine to treat many health problems, particularly pneumoconiosis. According to the study by the University of British Columbia, natural compound PCON6 has relatively selective cytotoxicity against NSCLC growth and represent a concept of developing a novel drug therapy specific for NSCLC based on the roots of C. connata or PCON6(35).

2. Juglans mandshurica Maxim
Juglanthraquinone C (1,5-dihydroxy-9,10-anthraquinone-3-carboxylic acid, JC), a naturally occurring anthraquinone isolated from the stem bark of Juglans mandshurica. Acording to the study by the Northeast Normal University, JC exhibited the strongest cytotoxicity of all compounds evaluated. Next, we used JC to treat several human cancer cell lines and found that JC showed an inhibitory effect on cell viability in dose-dependent (2.5-10 μg/ml JC) and time-dependent (24-48 h) manners(36).

3. Trichosanthes kirilowii Maximowicz
Trichosanthin (TCS) is a type I ribosome-inactivating protein that is isolated from the root tubers of the Chinese medicinal herb Trichosanthes kirilowii Maximowicz. According to the study by Zhejiang University School of Medicine, recent studies have demonstrated that TCS does indeed induce apoptosis in several tumor cell lines. Although TCS-induced apoptosis of tumor cell lines is now well known, the underlying mechanisms remain to be elucidated(37).

4. Rheum officinale Baill.
Rheum officinale Baill. (Da Huang) is one of the herbs commonly used in traditional Chinese medicine formulae against cancer. According to the study by The Hong Kong Polytechnic University, Da Huang water extract was found to have significant growth inhibitory effects on both A549 and MCF-7 cell lines with IC(50) values 620+/-12.7 and 515+/-10.1 microg/ml, respectively. Growth inhibitory effects were dose- and time-dependent. A significant decrease in cell number, DNA fragmentation and single DNA strand breakages were observed in the Da Huang water extract treated A549 and MCF-7 cells(38).


Chinese Food Therapy
The Best Way to prevent, treat your disease, including Obesity
and restore your health naturally with Chinese diet

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Super foods Library, Eat Yourself Healthy With The Best of the Best Nature Has to Offer

Sources
(a) http://www.ncbi.nlm.nih.gov/pubmed/22753285
(35) http://www.ncbi.nlm.nih.gov/pubmed/22864748
(36) http://www.ncbi.nlm.nih.gov/pubmed/22484481
(37) http://www.ncbi.nlm.nih.gov/pubmed/20225201
(38) http://www.ncbi.nlm.nih.gov/pubmed/19397973

Most Common Disease of 50plus: The Clinical trials and Studies of Musculo-Skeletal disorders(MSDs) - Polymyalagia Arthritis (Rheumatica): The Individual herbs - Devil's claw

Kyle J. Norton(Scholar and Master of Nutrients, all right reserved)Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

Musculoskeletal disorders (MSDs) are medical condition mostly caused by work related occupations and working environment, affecting patients’ muscles, joints, tendons, ligaments and nerves and developing over time. A community sample of 73 females and 32 males aged 85 and over underwent a standardised examination at home. Musculoskeletal pain was reported by 57% of those interviewed(1).

Types of Musculo-Skeletal disorders in elder(2)

1. Osteoarthritis
2. Gout
3. Rheumatoid Arthritis
4. Polymalagia Arthritis
5. Cervical myleopathy and spinal canal stenosis
6. Osteoporosis
7. Low back pain
8. Fibromyalgia


           Polymyalagia Arthritis (Rheumatica)


Polymalagia Arthritis is defined as a condition a common inflammatory rheumatic disease which causes pain, stiffness and tenderness in large muscles, including muscles shoulders and pelvic girdle as a result of the presence of a synovitis in proximal joints and periarticular structures.

                                       Treatments



B.2. Herbal and Traditional Chinese medicine
Herbal medicine from different cultures have been found effectively in reduced symptoms and treatment for patient with Polymyalagia Arthritis (Rheumatica), including
B.2.1. Individual herb
2. Devil's claw
Devil's claw also known as wood spider, is a plant of genus Harpagophytum in the family of Pedaliaceae, native to South Africa.The plant has been used as herb in traditional and herbal medicine to treat fever, rheumatoid arthritis, skin, gallbladder, pancreas, stomach and kidneys conditions, etc. Because of its strongly anti inflammatory activities, the herb may be used to treat inflammatory rheumatic disease, causing pain, stiffness and tenderness in large muscles. According to University Hospital Zurich, Extracts of devil's claw inhibited a wide range of proinflammatory mediators(199) which are important in the pathophysiology of inflammatory rheumatic disease(197).


Dr. Chrubasik S said that preparations of devil's claw extract, should be taken account of the presence of the quantity of harpagoside of which has proven importantly in relived painful lower back or arthrotic pain as an attractive alternative to synthetic analgesics(198).

Chinese Food Therapy
The Best Way to prevent, treat your disease, including Obesity
and restore your health naturally with Chinese diet


Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months


Super foods Library, Eat Yourself Healthy With The Best of the Best Nature Has to Offer


References
(197) Alteration of anti-inflammatory activity of Harpagophytum procumbens (devil's claw) extract after external metabolic activation with S9 mix by Hostanska K1, Melzer J, Rostock M, Suter A, Saller R.(PubMed)(198) [Devil's claw extract as an example of the effectiveness of herbal analgesics].[Article in German] by Chrubasik S1.(PubMed)
(199) Inhibitory effects of devil's claw (secondary root of Harpagophytum procumbens) extract and harpagoside on cytokine production in mouse macrophages by Inaba K1, Murata K, Naruto S, Matsuda H.(PubMed)

Tuesday, June 7, 2016

Traditional Chinese Medicine Herbal Therapy - Popular Herbal Chinese Herbs – Bai Wai (Radix Cynanchi Atrati)

Kyle J. Norton(Scholar and Master of Nutrients, all right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

                 Bai Wai (Radix Cynanchi Atrati)

Bai Wei is also known as Black Swallowwort Root. The bitter,salty and cold herb has been used in TCM to relieve edema, snake bite, toxic sores, swollen and painful throat; promotes urination, etc as it is used as Diuretic agent, clear Heat, cool Blood, expel toxins and resolve dermal ulcers by enhancing the function of lung, stomach, kidney channels.

Ingredients
1. Essential oil
2. Cynanchol
3. Atratoside A,B,C,D
4. Atratogenin A,B
5. Glaucogenin C
6. Cyantratoside A,BC,D,E,F
7. Glaucoside C
8. Cynjapogenin A
9. Thevetosied
10. Cynanversicoside A,B,C,D,E
11. Neocynanversicoside
12. Etc.

Health Benefits
1. Anti-cancers
Water extract of Cynanchi atrati Radix enhances the apoptotic and inflammatory response by inhibiting IKK-mediated NF-κB activation, according to the study of “Water extract of Cynanchi atrati Radix regulates inflammation and apoptotic cell death through suppression of IKK-mediated NF-κB signaling” by Jeon J, Park KA, Lee H, Shin S, Zhang T, Won M, Yoon HK, Choi MK, Kim HG, Son CG, Hong JH, Hur GM.(1).

2. Anti- inflammatory effects
Water extract of Radix Cynanchi Atrati has ererted the anti-inflammatory effect by inhibiting fever caused by 15% yeast suspension hypodermic injection in Rat, according to the study of “[Antifebrile and anti-inflammatory effects of radix Cynanchi atrati].[Article in Chinese]” by Xue B, Liang A, Yang Q, Fu M, Wang J.(2).

3. Neuroprotective effect
Chukmesundan (CMSD), composed of the following 8 medicinal herbs including Panex ginseng C.A. MEYER, Atractylodes macrocephala KOID, Poria cocos WOLF, Pinellia ternata BREIT, Brassica alba BOISS, Aconitum carmichaeli DEBX, Cynanchum atratum BGE(Bai wai) and Cuscuta chinensis LAM has exerted the Neuroprotective effect by by reducing the NO-mediated formation of free radicals or antagonizing their toxicity, according to the study of “Neuroprotective effect of a chuk-me-sun-dan on neurons from ischemic damage and neuronal cell toxicity” by Chung TW, Koo BS, Choi EG, Kim MG, Lee IS, Kim CH.(3).

4. Heart health
Bai wei has exerted the activity in stimulating of the heart muscle, improving contraction, slowing down heart rate, according to the study of “Bai wei” by Joe Hing Kwok Chu(4).

5. Etc.

The Obesity' Research and Studies: The Effective of Vitamin D

Kyle J. Norton(Scholar and Master of Nutrients, all right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.


Vitamin D is a fat-soluble secosteroids found in small amount in few foods, including salmon, mackerel, sardines and tuna. The vitamin plays an important role in modulation of cellular proliferation, apoptosis induction, tumor growth suppression and promotion in absorption of minerals, including calcium, iron, magnesium, phosphate and zinc.

The serum level of vitamin D
Low levels of micronutrients, including vitamin D are most common among overweight and obese children. According to the study, low serum 25-hydroxyvitamin D3 (25(OH)D) levels not only is associated to insulin resistance and cardiovascular diseases risks(817) but also incidence of obesity(818).
The study of Suspected Nonalcoholic Fatty Liver Disease in Chinese AmericanChildren also supported the link of obesity and metabolic syndrome among Chinese American childrenand suggested that testing for metabolic disorders and low vitamin D levels would be necessary to identify the early indication of NAFLD in childhood will allow for intervention with lifestyle modification, providing a means to reduce the prevalence of NAFLD in children and adults(819).
DR, Peterson CA, and Dr. Belenchia AM. told PubMed "There is a well-established inverse relationship between vitamin D status and obesity; however, it is unknown as to whether vitamin D deficiency contributes to, or is a consequence of obesity"(820). Some researchers suggested that correction of poor vitamin Dstatus through dietary supplementation may be an effective addition to the standard treatment of obesity and its associated insulin resistance(821) as vitamin D deficiency is accounted for the secular trends in the prevalence of obesity and for individual differences in its onset and severity(822).

Vitamin D and adiponectin
A suggestion of association of low levels of Vitamin D and adiponectin is associated to obesity instead of vitamin D itself(823).
Adiponectin is a protein involved in regulating glucose levels as well as fatty acid breakdown.
According to the study by the Università del Piemonte Orientale, in the confirmation Adiponectin tight association with obesity and diabetes mellitus, suggested that multimeric adiponectin may be a key plasma protein that links vitamin D deficiency to pediatric obesity(824).
In support the link between Vitamin D and adiponectin and obesity, the Ramathibodi Hospital, Mahidol University study showed that circulating adiponectin appears to be inversely related to beta cell dysfunction in addition to insulin resistance only in obese women(825). Other in the study insisted that since low serum levels of 1α,25-dihydroxycholecalciferol (DHCC) attenuates (monocyte chemotactic protein-1)MCP-1 and adiponectin production in human adipocytes, thereby reducing the expression of both pro- and anti-inflammatory factors may explain the difficulties so far in determining the role of DHCC in insulin sensitivity and obesity in human(826).

Taking altogether, low serum levels of vitamin D and vitamin D deficiency are associated to increase risk of obesity and obese complications through involvement of vary mechanisms. Over doses of vitamin D supplement may cause excessive calcium absorption, calcification, Urinary stones etc. please make sure to follow the guideline of the Institute of Medicine of the National Academies.


Chinese Food Therapy
The Best Way to prevent, treat your disease, including Obesity
and restore your health naturally with Chinese diet

Ovarian Cysts And PCOS Elimination

Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Super foods Library, Eat Yourself Healthy With The Best of the Best Nature Has to Offer

References
(1) Adiposity and metabolic dysfunction in polycystic ovary syndrome by Sam S.(PubMed)
(2) A "kiss" before conception: triggering ovulation with kisspeptin-54 may improve IVF by Young SL.(PubMed)
(3.) Androgen hyperfunction and excessive heterosexual hair growth in women, with special attention to the polycystic ovarian syndrome by Lunde O1.(PubMed)
(4) Expression of anti-Müllerian hormone in letrozole rat model of polycystic ovary syndrome by Du DF1, Li XL, Fang F, Du MR.(PubMed)
(5) [Serum levels of anti-muller hormone in women with polycystic ovary syndromeand healthy women of reproductive age].[Article in Bulgarian] by Parahuleva N, Pehlivanov B, Orbecova M, Deneva T, Uchikova E.(PubMed)
(6) [Current opinions on the etiology and pathophysiology of hirsutism].[Article in Polish] by Krysiak R1, Kedzia A, Okopień B.(PubMed)
(7) The clinical evaluation of hirsutism by Somani N1, Harrison S, Bergfeld WF.(PubMed)
(8) Polycystic ovary syndrome and insulin: our understanding in the past, present and future by Mayer SB1, Evans WS, Nestler JE.(PubMed)
(9) Association of mean platelet volume with androgens and insulin resistance in nonobese patients with polycystic ovary syndrome by Dogan BA1, Arduc A2, Tuna MM1, Karakılıc E1, Dagdelen I1, Tutuncu Y1, Berker D1, Guler S1.(PubMed)
(10) Approach to the patient: contraception in women with polycystic ovary syndrome by Yildiz BO1.(PubMed)
(11) Polycystic ovarian syndrome (PCOS): a significant contributor to the overall burden of type 2 diabetes in women by Talbott EO1, Zborowski JV, Rager JR, Kip KE, Xu X, Orchard TJ.(PubMed)
(12) Prevalence of vitamin D deficiency in Slovak women with polycystic ovary syndrome and its relation to metabolic and reproductive abnormalities by Figurová J1, Dravecká I, Javorský M, Petríková J, Lazúrová I.(PubMed)
(13) Role of Insulin Sensitizers on Cardiovascular Risk Factors in Polycystic Ovarian Syndrome: A Meta-Analysis by Thethi TK1, Katalenich B2, Nagireddy P3, Chabbra P4, Kuhadiya N5, Fonseca V1.(PubMed)
(14) Acne in hirsute women by Lumezi BG1, Pupovci HL1, Berisha VL1, Goçi AU2, Gerqari A3.(PubMed)
(15) Obesity and polycystic ovary syndrome by Naderpoor N1, Shorakae S, Joham A, Boyle J, De Courten B, Teede HJ.(PubMed)
(16) Polycystic ovary syndrome: a complex condition with psychological, reproductive and metabolic manifestations that impacts on health across the lifespan by Teede H1, Deeks A, Moran L.(PubMed)
(17) Metabolic Evidence of Diminished Lipid Oxidation in Women With Polycystic Ovary Syndrome. by Whigham LD1, Butz DE2, Dashti H3, Tonelli M3, Johnson LK1, Cook ME2, Porter WP4, Eghbalnia HR5, Markley JL6, Lindheim SR7, Schoeller DA8, Abbott DH9, Assadi-Porter FM10.(PubMed)
(18) Risk of endometrial, ovarian and breast cancer in women with polycystic ovary syndrome: a systematic review and meta-analysis by Barry JA1, Azizia MM1, Hardiman PJ2.(PubMed)
(19) Risk of cancer among women with polycystic ovary syndrome: a Danish cohort study by Gottschau M1, Kjaer SK2, Jensen A1, Munk C1, Mellemkjaer L3.(PubMed)
(20) Polycystic ovary syndrome: metabolic consequences and long-term management by Carmina E1.(PubMed)
(21) Arterial stiffness is increased in asymptomatic nondiabetic postmenopausal women with a polycystic ovary syndrome phenotype by Armeni E1, Stamatelopoulos K, Rizos D, Georgiopoulos G, Kazani M, Kazani A, Kolyviras A, Stellos K, Panoulis K, Alexandrou A, Creatsa M, Papamichael C, Lambrinoudaki I.(PubMed)
(733) [Treatment of PCOS without IVF: weight loss, insulin-sensitizing agents].[Article in French] by Pugeat M1.(PubMed)
(734) A 12-week treatment with the long-acting glucagon-like peptide 1 receptor agonist liraglutide leads to significant weight loss in a subset of obese women with newly diagnosed polycystic ovary syndrome by Jensterle M1, Kravos NA1, Pfeifer M1, Kocjan T1, Janez A1.(PubMed)
(735) Body mass index and gonadotropin hormones (LH & FSH) associate with clinical symptoms among women with polycystic ovary syndrome by Esmaeilzadeh S, Andarieh MG1, Ghadimi R, Delavar MA.(PubMed)
(736) Obesity and polycystic ovary syndrome by Naderpoor N1, Shorakae S, Joham A, Boyle J, De Courten B, Teede HJ.(737)
(737) Polycystic ovary syndrome: a complex condition with psychological, reproductive and metabolic manifestations that impacts on health across the lifespan by Teede H1, Deeks A, Moran L.(PubMed)
(738) A retrospective study of the pregnancy, delivery and neonatal outcome in overweight versus normal weight women with polycystic ovary syndrome by De Frène V1, Vansteelandt S2, T'Sjoen G3, Gerris J4, Somers S4, Vercruysse L4, De Sutter P4.(PubMed)
(817) The association of vitamin D status with cardiometabolic risk factors, obesityand puberty in children by Aypak C1, Türedi O, Yüce A.(PubMed)
(818) Serum 25-hydroxyvitamin D (25-OH-D) in obese adolescents by Garanty-Bogacka B1, Syrenicz M, Goral J, Krupa B, Syrenicz J, Walczak M, Syrenicz A.(PubMed)
(819) Prevalence and Correlates of Suspected Nonalcoholic Fatty Liver Disease in Chinese American Children by Malespin M1, Sleesman B, Lau A, Wong SS, Cotler SJ.(PubMed)
(820) Vitamin D deficiency & childhood obesity: a tale of two epidemics by Peterson CA, Belenchia AM.(PubMed)
(821) Correcting vitamin D insufficiency improves insulin sensitivity in obese adolescents: a randomized controlled trial by Belenchia AM1, Tosh AK, Hillman LS, Peterson CA.(PubMed)
(822) Vitamin D deficiency is the cause of common obesity by Foss YJ.(PubMed)
(823) Cardiometabolic risk factors related to vitamin d and adiponectin in obese children and adolescents by Kardas F1, Kendirci M, Kurtoglu S.(PubMed)
(824) Pediatric obesity and vitamin D deficiency: a proteomic approach identifies multimeric adiponectin as a key link between these conditions by Walker GE1, Ricotti R2, Roccio M1, Moia S1, Bellone S2, Prodam F2, Bona G2.(PubMed)
(825) Differences in insulin sensitivity, pancreatic beta cell function and circulating adiponectin across glucose tolerance status in Thai obese and non-obese women by Chailurkit LO1, Chanprasertyothin S, Jongjaroenprasert W, Ongphiphadhanakul B.(PubMed)
(826) Differential effects of 1α,25-dihydroxycholecalciferol on MCP-1 andadiponectin production in human white adipocytes by Lorente-Cebrián S1, Eriksson A, Dunlop T, Mejhert N, Dahlman I, Aström G, Sjölin E, Wåhlén K, Carlberg C, Laurencikiene J, Hedén P, Arner P, Rydén M.(PubMed)
(827) Diet and nutrition in polycystic ovary syndrome (PCOS): pointers for nutritional management by Farshchi H, Rane A, Love A, Kennedy RL(PubMed)

Most Common Disease of 50plus: The Clinical trials and Studies of Musculo-Skeletal disorders(MSDs) - Polymyalagia Arthritis (Rheumatica) Treatment: Individual herb: Devil's claw

Kyle J. Norton(Scholar and Master of Nutrients, all right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

Musculoskeletal disorders (MSDs) are medical condition mostly caused by work related occupations and working environment, affecting patients’ muscles, joints, tendons, ligaments and nerves and developing over time. A community sample of 73 females and 32 males aged 85 and over underwent a standardised examination at home. Musculoskeletal pain was reported by 57% of those interviewed(1).

Types of Musculo-Skeletal disorders in elder(2)
1. Osteoarthritis
2. Gout
3. Rheumatoid Arthritis
4. Polymalagia Arthritis
5. Cervical myleopathy and spinal canal stenosis
6. Osteoporosis
7. Low back pain
8. Fibromyalgia


                 Polymyalagia Arthritis (Rheumatica)


Polymalagia Arthritis is defined as a condition a common inflammatory rheumatic disease which causes pain, stiffness and tenderness in large muscles, including muscles shoulders and pelvic girdle as a result of the presence of a synovitis in proximal joints and periarticular structures.

                             Treatments


B.2. Herbal and Traditional Chinese medicine
Herbal medicine from different cultures have been found effectively in reduced symptoms and treatment for patient with Polymyalagia Arthritis (Rheumatica), including
B.2.1. Individual herb
2. Devil's claw
Devil's claw also known as wood spider, is a plant of genus Harpagophytum in the family of Pedaliaceae, native to South Africa.The plant has been used as herb in traditional and herbal medicine to treat fever, rheumatoid arthritis, skin, gallbladder, pancreas, stomach and kidneys conditions, etc. Because of its strongly anti inflammatory activities, the herb may be used to treat inflammatory rheumatic disease, causing pain, stiffness and tenderness in large muscles. According to University Hospital Zurich, Extracts of devil's claw inhibited a wide range of proinflammatory mediators(199) which are important in the pathophysiology of inflammatory rheumatic disease(197).
Dr. Chrubasik S said that preparations of devil's claw extract, should be taken account of the presence of the quantity of harpagoside of which has proven importantly in relived painful lower back or arthrotic pain as an attractive alternative to synthetic analgesics(198).


Chinese Food Therapy
The Best Way to prevent, treat your disease, including Obesity
and restore your health naturally with Chinese diet


Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months


Super foods LibraryEat Yourself Healthy With The Best of the Best Nature Has to Offer


References
(197) Alteration of anti-inflammatory activity of Harpagophytum procumbens (devil's claw) extract after external metabolic activation with S9 mix by Hostanska K1, Melzer J, Rostock M, Suter A, Saller R.(PubMed)(198) [Devil's claw extract as an example of the effectiveness of herbal analgesics].[Article in German] by Chrubasik S1.(PubMed)
(199) Inhibitory effects of devil's claw (secondary root of Harpagophytum procumbens) extract and harpagoside on cytokine production in mouse macrophages by Inaba K1, Murata K, Naruto S, Matsuda H.(PubMed)

The Best Smoothie of Blueberry, Tomato, Turmeric and Grape Juice for Prevention and Treatment of Neonatal Hepatitis

Kyle J. Norton(Scholar, Master of Nutrients), all right reserved.
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
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Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

The smoothie for prevention and treatment of  Neonatal Hepatitis
Yield: 2 servings (about 8 ounces each)
3/4  cup blue berry
3/4 cup tomato
1 tsp curcumin
1 cup grape juice

1. Place all ingredients in a blender and puree about 1 minute
2. Blend on high speed about 1 minute or until the mixture is thick and the ice is well crushed.
3. Serve immediately

The finding of a natural source for treatment of   Neonatal Hepatitis has been running into many obstacles, many ingredients showed initially with promising result in animal studies have not produced same potentials in large sample size and mutli centers human trials.

Neonatal Hepatitis is a condition of liver inflammatory liver diseases occurred in the newborn, mostly within one to two months after birth. According to liver foundation anti viral infection together with intake of vitamin A, D and K should be helpful in fighting of free radicals in induction of oxidative stress(1).

Recent studies back by well known institutions proposed, Blueberry, Tomato, Turmeric and Grape Juice may be the next generation of natural ingredients for prevention and treatment of Neonatal Hepatitis.

Resveratrol is a phytochemical in the class of Stilbenoids, found abundantly in grape and blueberry may be a potent antioxidant for reduced risk and treatment of neonatal Hepatitis, through its anti viral infection(2). 
Accoridng to the IQ Institute of Infection and Immunity, resveratrol, the anti viral key molecules inhibited against HCV genotype 3a (GT3a) may offer an alternative attraction to target the viral helicase for treatment of hepatitis(3).
In a new human hepatoma cell line system for hepatitis C virus, the anioxidant effectively trigger autophagic cell death through the increased expression of autophagy through cell cycle arrest(4).

Turmeric is a perennial plant in the genus Curcuma, belongings to the family Zingiberaceae, native to tropical South Asia. The herb has been used in trditional medicine as anti-oxidant, hypoglycemic, colorant, antiseptic, wound healing agent, and to treat flatulence, bloating, and appetite loss, ulcers, eczema, inflammations, etc. Its phytochemical curcumin expressed anti hepatitis B virus (HBV) effect through inhibited HBV gene expression and replication(5).
According to the German Cancer Research Center (DKFZ), curcumin also reduced tumor incidence at other organ sites and suppressed formation of metastases and should be considered as a contra-indicated for patients suffering from inherited and acquired metal storage diseases that include patients with hepatitis C virus infection(6).
Curcuminoids, derived from the plant Curcuma domestica Val derivatives of curcumin, are effective in suppressing the hepatic microvascular inflammatory response against lipopolysacharide (LPS) through ameliorated expression of inflammatory cytokines(7).

Carotenoids, found abundantly in carrot and tomato also attenuated risk and treatment of neonatal hepatitis C through exhibition of synergistic effect(8). According to the Tongji Medical College, Huazhong University of Science and Technology, lutein, a member of carotenoids inhibited the activity of HBV through suppressed the secretion of HBsAg(antigen) from HepG2 2.2.15 cells in a dose-dependent manner(9).
Dr, Mawson AR and Dr. Steele TA., professors at the Des Moines University Osteopathic Medical Center, said, "The reduced rate of survival of liver grafts in patients with HBV infection could also be due to the continued presence of the virus, stimulated by retinoids in the graft tissue. "(10).

The effectiveness of Blueberry, Tomato, Turmeric and Grape Juice  may serve as cornerstones of pharmaceutical target for further studies in production of a potential medication for reduced risk, complications and treatment of Neonatal Hepatitis with little or no adverse effects.
Women who are at high risk of Neonatal Hepatitis due to family history, environment factors, .... should drink at least one serving daily and women with Neonatal Hepatitis should drink the smoothie as much as they can, depending to digestive toleration.
We don't recommend smoothie for newborn
Life style and dietary patter change are recommended.

References
(1) How Is Neonatal Hepatitis Defined?(The liver disorder foundation)
(2) Identification of a resveratrol tetramer as a potent inhibitor of hepatitis C virus helicase by Lee S1, Yoon KD2, Lee M3, Cho Y3, Choi G3, Jang H4, Kim B5, Jung DH6, Oh JG2, Kim GW7, Oh JW7, Jeong YJ6, Kwon HJ5, Bae SK2, Min DH4, Windisch MP3,Heo TH2, Lee C1.(PubMed)
(3) Docking studies of Pakistani HCV NS3 helicase: a possible antiviral drug target. by Fatima K1, Mathew S2, Suhail M3, Ali A3, Damanhouri G3, Azhar E3, Qadri I3.(PubMed)
(4) Resveratrol arrests cell cycle and induces apoptosis in human hepatocellular carcinoma Huh-7 cells by Liao PC1, Ng LT, Lin LT, Richardson CD, Wang GH, Lin CC.(PubMed)
(5) Curcumin inhibits hepatitis B virus via down-regulation of the metabolic coactivator PGC-1alpha. by Rechtman MM1, Har-Noy O, Bar-Yishay I, Fishman S, Adamovich Y, Shaul Y, Halpern Z, Shlomai A.(PubMed)
(6) No prevention of liver and kidney tumors in Long-Evans Cinnamon rats by dietary curcumin, but inhibition at other sites and of metastases by Frank N1, Knauft J, Amelung F, Nair J, Wesch H, Bartsch H.(PubMed)
(7) Effect of curcuminoids as anti-inflammatory agents on the hepatic microvascular response to endotoxin by Lukita-Atmadja W1, Ito Y, Baker GL, McCuskey RS.(PubMed)
(8) Retinoids and rexinoids inhibit hepatitis C virus independently of retinoid receptor signaling by Murakami Y1, Fukasawa M2, Kaneko Y3, Suzuki T4, Wakita T5, Fukazawa H6.(PubMed)
(9) In vitro antiviral activity of lutein against hepatitis B virus by Pang R1, Tao JY, Zhang SL, Zhao L, Yue X, Wang YF, Ye P, Dong JH, Zhu Y, Wu JG.(PubMed)
(10) Possible role of retinoids in hepatitis B virus-associated liver damage By Mawson AR1, Steele TA.(PubMed)