Sunday, June 12, 2016

Phytochemicals in Foods - The Effects of Astaxanthin

Kyle J. Norton(Scholar and Master of Nutrients, all right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.


                         Astaxanthin


Astaxanthin is a phytochemincal in the class of Xanthophylls , belonging to the group of Carotenoids (tetraterpenoids), found abundantly in yeast, krill, shrimp, salmon, lobsters, etc.

Health Benefits
1. Male infertility
In the investigation of the effects of Astaxanthin 16 mg/day (AstaCarox, AstaReal AB, Gustavsberg, Sweden) or placebo for 3 months treatment on semen parameters, reactive oxygen species (ROS), zona-free hamster oocyte test, serum hormones including testosterone, luteinizing hormone (LH), follicle stimulating hormone (FSH) and Inhibin B, and spontaneous or intrauterine insemination (IUI)-induced pregnancies, found that ROS and Inhibin B decreased significantly and sperm linear velocity increased in the Astaxanthin group (n = 11), but not in the placebo group (n = 19). The results of the zona-free hamster oocyte test tended to improve in the Astaxanthin group in contrast with the placebo group, though not reaching statistical significance. The total and per cycle pregnancy rates among the placebo cases (10.5 % and 3.6 %) were lower compared with 54.5 % and 23.1 % respectively in the Astaxanthin group (P = 0.028; P = 0.036), according to "Combined conventional/antioxidant "Astaxanthin" treatment for male infertility: a double blind, randomized trial" by Comhaire FH, El Garem Y, Mahmoud A, Eertmans F, Schoonjans F.(1)

2. Functional dyspepsia
In the evaluation of the efficacy of the natural antioxidant astaxanthin in functional dyspepsia in different doses and compared with placebo, found that at the end of therapy (week 4) no difference between the three treatment groups was observed regarding mean Gastrointestinal Symptom Rating Scale (GSRS) scores of abdominal pain, indigestion and reflux syndromes. The same results were observed at the end of follow-up. However reduction of reflux syndrome before treatment to week 4 was significantly pronounced in the higher (40mg) dose compared to the other treatment groups (16mg and placebo, p=0.04), according to "Efficacy of the natural antioxidant astaxanthin in the treatment of functional dyspepsia in patients with or without Helicobacter pylori infection: A prospective, randomized, double blind, and placebo-controlled study" by Kupcinskas L, Lafolie P, Lignell A, Kiudelis G, Jonaitis L, Adamonis K, Andersen LP, Wadström T.(2)

3. Anti-aging
In the review of the effects of Astaxanthin, a xanthophyll carotenoid, cell membrane nutrient with diverse clinical benefits indicated that in preliminary trials it showed promise for sports performance (soccer). In cultured cells, astaxanthinprotected the mitochondria against endogenous oxygen radicals, conserved their redox (antioxidant) capacity, and enhanced their energy production efficiency. The concentrations used in these cells would be attainable in humans by modest dietary intakes. Astaxanthin's clinical success extends beyond protection against oxidative stress and inflammation, to demonstrable promise for slowing age-related functional decline, according to "Astaxanthin, cell membrane nutrient with diverse clinical benefits and anti-aging potential" by Kidd P.(3)

4. Cardiovascular health
In the evualation of the an antioxidant with anti-inflammatory properties effects and as such has potential as a therapeutic agent in atherosclerotic cardiovascular disease of Astaxanthin, a xanthophyll carotenoid present in microalgae, fungi, complex plants, seafood, flamingos and quail, found that No adverse events have been reported and there is evidence of a reduction in biomarkers of oxidative stress and inflammation with astaxanthin administration. Experimental studies in several species using an ischaemia-reperfusion myocardial model demonstrated that astaxanthin protects the myocardium when administered both orally or intravenously prior to the induction of the ischaemic event, according to "Astaxanthin: a potential therapeutic agent in cardiovascular disease" by Fassett RG, Coombes JS.(4)

5. Antithrombotic and antihypertensive effects
In the examination of the hypothesis that astaxanthin, a red pigment carotenoid found in salmonid and crustacean aquaculture, for its protect on stroke-prone spontaneously hypertensive rats (SHRSP) from vascular oxidative damage, hypertension, and cerebral thrombosis, found that the results supported our hypothesis and strongly suggested that the antithrombotic and antihypertensive effects of astaxanthin or vitamin E may be related to an increase in bioavailable NO, possibly mediated by decreased inactivation of NO by reactive oxygen species, according to "Astaxanthin inhibits thrombosis in cerebral vessels of stroke-prone spontaneously hypertensive rats" by Sasaki Y, Kobara N, Higashino S, Giddings JC, Yamamoto J.(5)


6. Cholesterol
In a randomized, double-blind, placebo-controlled study to investigate the effects of astaxanthin on lipid profiles and oxidative stress in overweight and obese adults in Korea, found that all four biomarkers were not significantly different between the two groups. Compared with the placebo group, MDA and ISP were significantly lower, but TAC was significantly higher in the astaxanthin group at 12 weeks. These results suggest that supplementary astaxanthin has positive effects by improving the LDL cholesterol, ApoB, and oxidative stress biomarkers, according to "Positive effects of astaxanthin on lipid profiles and oxidative stress in overweight subjects" by Choi HD, Youn YK, Shin WG.(6)

7. Immune system
In the testing astaxanthin, a potent antioxidant carotenoid and its role in modulating immune response in cats, found that there was a dose-related increase in plasma astaxanthin concentrations, with maximum concentrations observed on wk 12. Dietary astaxanthin enhanced DTH response to both the specific (vaccine) and nonspecific (concanavalin A) antigens. In addition, cats fed astaxanthin had heightened PBMC proliferation and NK cell cytotoxic activity. The population of CD3(+) total T and CD4(+) T helper cells were also higher in astaxanthin-fed cats; however, no treatment difference was found with the CD8(+) T cytotoxic and MHC II(+) activated lymphocyte cell populations. Dietary astaxanthin increased concentrations of plasma IgG and IgM. Therefore, dietary astaxanthin heightened cell-mediated and humoral immune responses in cats, according to "Astaxanthinstimulates cell-mediated and humoral immune responses in cats" by Park JS, Mathison BD, Hayek MG, Massimino S, Reinhart GA, Chew BP.(7)

8. Non-alcoholic fatty liver disease
In the management of non-alcoholic fatty liver disease in full-spectrum antioxidant therapy featuring astaxanthin coupled with lipoprivic strategies and salsalate, indicated that Astaxanthin and spirulina appear to have considerable potential for controlling the oxidative stress associated with NAFLD - the former because it may help to prevent the mitochondrial damage that renders mitochondria a key source of superoxide in this syndrome, the latter because it is exceptionally rich in phycocyanobilin, a phytochemical inhibitor of NAPDH oxidase, according to "Full-spectrum antioxidant therapy featuring astaxanthin coupled with lipoprivic strategies and salsalate for management of non-alcoholic fatty liver disease" by McCarty MF.(8)

9. Diabetic complications
In the examination of whether astaxanthin (ASX, 3,3-dihydroxybeta, beta-carotene-4,4-dione, CAS 472-61-7), a dietary antioxidant carotenoid that is naturally present in algae, crustaceans, and fish, has a protective effect on endothelial dysfunction of aortas in diabetic rats and the possible molecular mechanism involved, indicated that ASX could ameliorate diabetic endothelial dysfunction by inhibiting the ox-LDLLOX-1-eNOS pathway. Treatment with ASX might be clinically useful for diabetic complications associated with endothelial dysfunction, according to "Ameliorative effect of astaxanthin on endothelial dysfunction in streptozotocin-induced diabetes in male rats" by Zhao ZW, Cai W, Lin YL, Lin QF, Jiang Q, Lin Z, Chen LL.(9)

10. Colon Health
In the investigation of the possible inhibitory effect of AX against inflammation-related mouse colon carcinogenesis and dextran sulfate sodium (DSS)-induced colitis in male ICR mice, found that the dietary AX suppresses the colitis and colitis-related colon carcinogenesis in mice, partly through inhibition of the expression of inflammatory cytokine and proliferation. Our findings suggest that AX is one of the candidates for prevention of colitis and inflammation-associated colon carcinogenesis in humans, according to "Dietary astaxanthin inhibits colitis and colitis-associated colon carcinogenesis in mice via modulation of the inflammatory cytokines" by Yasui Y, Hosokawa M, Mikami N, Miyashita K, Tanaka T.(10)

11. Anti cancers
In the investigation of the pharmacological roles of carotenoids in the prevention and reduction of cancer incidence, found that carotenoids up-regulated the expression of PPARγ and p21 and down-regulated the expression of cyclin D1 in a dose-dependent manner. In addition, β-carotene, astaxanthin, capsanthin and bixin also up-regulated the expression of Nrf2, an important transcription factor in Keap1-Nrf2/EpRE/ARE signaling pathway. It appears to us that PPARγ signaling pathways and Keap1-Nrf2/EpRE/ARE signaling pathway were involved in the inhibition of K562 cell proliferation by carotenoids and the up-regulation of PPARγ expression at least partly contributed to the antiproliferative effects of β-carotene,astaxanthin, capsanthin, and bixin on K562 cells, according to "Carotenoids inhibit proliferation and regulate expression of peroxisome proliferators-activated receptor gamma (PPARγ) in K562 cancer cells" by Zhang X, Zhao WE, Hu L, Zhao L, Huang J.(11)

12. Anxiolytic effects
In the study of study of the combined effect of ASTA and fish oil on the redox status in plasma and in the monoaminergic-rich anterior forebrain region of Wistar rats with possible correlations with the anxiolytic behavior, found that ASTA properly crosses the brain-blood barrier, our data also address a possible indirect role of ASTA in restoring basal oxidative conditions in anterior forebrain of animals: by improving GSH-based antioxidant capacity of plasma. Preliminary anxiolytic tests performed in the elevated plus maze are in alignment with our biochemical observations, according to "Astaxanthin limits fish oil-related oxidative insult in the anterior forebrain of Wistar rats: putative anxiolytic effects?" by Mattei R, Polotow TG, Vardaris CV, Guerra BA, Leite JR, Otton R, Barros MP.(12)

13. Antioxidants
In a randomized, double-blind study was performed to investigate the effect ofastaxanthin (ASX), which is known to be a potent antioxidant, on oxidative stress in overweight and obese adults in Korea, found that compared with baseline, the MDA (by 34.6% and 35.2%) and ISP (by 64.9% and 64.7%) levels were significantly lowered, whereas SOD (by 193% and 194%) and TAC (by 121% and 125%) levels were significantly increased in two dose groups after the 3 week intervention. This study revealed that supplemental ASX for 3 weeks improved oxidative stress biomarkers by suppressing lipid peroxidation and stimulating the activity of the antioxidant defense system, according to "Effects of astaxanthinon oxidative stress in overweight and obese adults" by Choi HD, Kim JH, Chang MJ, Kyu-Youn Y, Shin WG.(13)

14. Anti inflammatory effects
In the examination focused on the antioxidant effect of Astaxanthin (AST) and investigation of the efficacy of AST in endotoxin-induced uveitis (EIU) in rats, found that AST suppressed the development of EIU in a dose-dependent fashion. The anti-inflammatory effect of 100 mg/kg AST was as strong as that of 10 mg/kg prednisolone. AST also decreased production of NO, activity of inducible nitric oxide synthase (NOS), and production of PGE2 and TNF-alpha in RAW264.7 cells in vitro in a dose-dependent manner, according to "Effects of astaxanthin on lipopolysaccharide-induced inflammation in vitro and in vivo" by Ohgami K, Shiratori K, Kotake S, Nishida T, Mizuki N, Yazawa K, Ohno S.(14)

15. Neuroprotective effect
In the study, carried out to further investigate the neuroprotective effect of AST on oxidative stress induced toxicity in primary culture of cortical neurons and on focal cerebral ischemia-reperfusion induced brain damage in rats, found that the neuronal injury was significantly improved by pretreatment of AST at 80mg/kg. Taken together, these results suggest that pretreatment with AST exhibits noticeable neuroprotection against brain damage induced by ischemia-reperfusion and the antioxidant activity of AST maybe partly responsible for it, according to "Neuroprotective effect of astaxanthin on H(2)O(2)-induced neurotoxicity in vitro and on focal cerebral ischemia in vivo" by Lu YP, Liu SY, Sun H, Wu XM, Li JJ, Zhu L.(15)

16. Dihydrotestosterone, testosterone and estradiol levels
In a clinical study of clinically, 42 healthy males ages 37 to 70 years were divided into two groups of twenty-one and dosed with either 800 mg/day or 2000 mg/day of Alphastat(R) (Mytosterone(trade mark)) for fourteen days, found that both dose groups showed significant (p = 0.05) increases in T and decreases in DHT within three days of treatment with Alphastat(R) (Mytosterone(trade mark)). Between group statistical analysis showed no significant (p = 0.05) difference, indicating the effect was not dose dependent and that 800 mg/per day is equally effective as 2000 mg/day for increasing T and lowering DHT. Blood levels of ES however, decreased significantly (p = 0.05) in the 2000 mg/day dose group but not in the 800 mg/day dose group indicating a dose dependant decrease in E levels, according to "An open label, dose response study to determine the effect of a dietary supplement on dihydrotestosterone, testosterone and estradiol levels in healthy males" by Angwafor F 3rd, Anderson ML.(16)

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and restore your health naturally with Chinese diet


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Sources
(1) http://www.ncbi.nlm.nih.gov/pubmed/16110353
(2) http://www.ncbi.nlm.nih.gov/pubmed/18467083
(3) http://www.ncbi.nlm.nih.gov/pubmed/22214255
(4) http://www.ncbi.nlm.nih.gov/pubmed/21556169
(5) http://www.ncbi.nlm.nih.gov/pubmed/22074803
(6) http://www.ncbi.nlm.nih.gov/pubmed/21964877
(7) http://www.ncbi.nlm.nih.gov/pubmed/21930306
(8) http://www.ncbi.nlm.nih.gov/pubmed/21764223
(9) http://www.ncbi.nlm.nih.gov/pubmed/21650083
(10) http://www.ncbi.nlm.nih.gov/pubmed/21621527
(11) http://www.ncbi.nlm.nih.gov/pubmed/21620794
(12) http://www.ncbi.nlm.nih.gov/pubmed/21619892
(13) http://www.ncbi.nlm.nih.gov/pubmed/21480416
(14) http://www.ncbi.nlm.nih.gov/pubmed/12766075
(15) http://www.ncbi.nlm.nih.gov/pubmed/20846510
(16) http://www.ncbi.nlm.nih.gov/pubmed/18700016

Most Common Diseases of Men of 50Plus - Testosterone Deficiency - The Complication of Prostate Disease

Kyle J. Norton(Scholar and Master of Nutrients, all right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

I. Introduction
Testosterone deficiency
Testosterone is a male hormone. Besides promoting libido, it has other important functions such as maintaining muscle mass and forming bone, and regulating heart muscle and cholesterol. It also helps to improve the oxygen levels throughout the body as well as controlling blood glucose and strengthening the immune system. Starting at age 40 levels of testosterone start to diminish, the levels of the by-product prolactin of testosterone of men increases, stimulating the production of the enzyme 5-alpha reductase that causes the conversion of testosterone to gihydro-testosterones DHT thus triggering low levels of testosterone.

Prostate Gland
Prostate gland is a gland that makes and stores semen. It is located below the bladder and surrounds the tube that carries urine out of your body. starting at age 40,the levels of the by-product prolactin of testosterone of men increases, stimulating the production of the enzyme 5-alpha reductase that causes the conversion of testosterone to gihydro-testosterones DHT triggering prostate enlargement and other problems. Therefore in order to prevent the symptoms of enlarged prostate is to naturally impend the conversion of testosterone to DHT. Unfortunately, aging is not the only cause of enlarged prostate.

II. Causes of enlarged prostate and prostate cancer because of testosterone deficiency
By the age of 40, the levels of testosterone of men start to decrease resulting in the by-product prolactin of testosterone of men to increase, stimulating the production of the enzyme 5-alpha reductase that causes the conversion of testosterone to gihydro-testosterones DHT triggering prostate enlargement and prostate cancer. Excess estrogen seems to be the culprit in prostate enlargement that leads to the pathology and favors the development of prostate cancer.

III. Symptoms of enlarged prostate and prostate cancer because of testosterone deficiency
1. Frequent or difficult urination
2. Dribbling
3. Urinary urgency
4. Discomfort/pain in the penis
5. Low back pain
6. Reduced urinary stream
7. Hesitancy before or during urination
8. Reducing sexual desire
9. Anxiety about having sex
10. Need to urinate often especially at night
11. Blood in urine
12. Burning during urine
13. Painful ejaculation

III. Prevention and Treatment
In this case, since the problem of prostate gland is caused by testosterone deficiency it is the urgent need to increase the levels of testosterone and provide nutrition for the prostate.
A) Natural remedies for preventing and treating testosterone deficiency
1. Dark green leaf
Dark green leaf juice contains high amounts of vitamins C and E. Besides helping to reduce levels of cholesterol, high blood pressure and regulate blood glucose resulting in improved blood circulation to vital organs in our body. It also helps to fight the forming of free radicals and rejuvenates our cell and cleans up the clogged up receptor sites that helps to raise levels of testosterone.

2.Goat Meat
Goat meat contains high amounts of protein, iron, magnesium, and zinc. Iron specifically offers the added benefit of raising levels of oxygen in the blood that is essential for providing nutrition to cell needs. High protein and zinc are two nutrients that help to optimize free testosterone levels and muscle-building.

3. Cold water fish
Besides plenty of omega 3, cold water fish is an excellent source of vitamin A and zinc that help the binding of sex hormones, specifically testosterone and estradiol.

4. Muira Pauma
Muira pauma are stems and roots of a ptychopetalum plant in South America. It has been used as an aphrodisiac, tonic and cure for muscle paralysis and strengthening the liver function that helps to cure the hormone imbalance in aging men. Study shows that muira pauma is a libido enhancer.

5. Milk thistle
Milk thistle helps restore the liver function that helps to eliminate the surplus of estrogen and sex hormone binding globulin that allow the increasing of levels of free testosterone.

6. Maca
Maca is a vegetable root or tuber that grows in the high Andean plateaus of Peru at high altitudes. It helps our body to nourish the pituitary gland that helps to increase the production of our own human hormones such as testosterone.

7. Ginseng
Ginseng in Chinese medicine is used as a pituitary strengthening herb. It also contains herbs that benefits the endocrine system in resulting of tonifying the entire endocrine system and helping the release of human growth hormone (HGH).

8. Horny Goat Weed
orny goat weed contains a variety of flavonoids such as icariin that helps to relax the blood vessels leading to the penis, which allows them to expand resulting in a stronger and harder erection. It also helps to treat low levels of testosterone and increase sexual desire at the same time.

9. DHEA
DHEA allows our body to create other hormones such as testosterone. Study shows that DHEA is a precursor to sex hormones, the deficiency of DHEA causes the deficiency of other sex hormones resulting in a loss of bone density, increasing of body mass, hardening of blood vessels, and low sex drive.

10. Chorella
Chlorella containing beta carotene and chlorophyll is a powerful antioxidant that helps to strengthen the immune system by blocking the formation of free radicals, improving oxygen levels for cell needs and nitric oxygen stimulating the enlargement of the penis through sexual desire.

11. Zinc and iron
Deficiency of zinc and iron causes the depletion of oxygen level and poor circulation of the bloodstream as undirectly resulting in erectile dysfunction. Since zinc also promotes healthy prostate glands that increases the release of prostate fluids that helps to stimulate the sexual desire by increasing the production of levels of free testosterone.

B) Natural remedies for preventing and treating prostate cancer and enlarged prostate
1. Soy bean and legume
Soybeans and legumes contains isoflavones and is a unique source of phytochemicals It directly inhibits the growth of different types of cancer cells and protects the prostate from being enlarged. Study shows that isoflavones were found to markedly inhibit prostate tumors in mice implanted with prostate cancer cells. Try adding soy or rice milk to your morning cereal or oatmeal.

2. Papaya
Papayas are rich in antioxidants, vitamin E, vitamin C, vitamin A, carotenoids and flavonoids that have cardio protective and anti-cancer effects. Eating papayas help to promote lung health and prevents the prostate from becoming enlarged and prevents prostate cancer.

3. Green tea
Green tea contains the antioxidant phytochemicals called polyphenols that attack growth factors and proteins, interrupting processes that increase the size of tumors, thus preventing them from spreading to other parts of the body. Green tea also help to prevent the development of benign prostate hyperplasia such as enlarged prostate and prostate cancer.

4. Bee pollen
Bee pollen is an antioxidant containing high amounts of flavonoids, zinc and many other elements needed by our bodies. It has an astounding record at reversing prostate cancer and other prostate problems such as enlarged prostate.

5. Glycine
Glycine is also found in fairly large amounts in the prostate fluid and may for this reason be important in prostate health. It is required to build proteins in the body and synthesis of nucleic acids, the construction of RNA as well as DNA, bile acids and other amino acids in the body. Study shows that glycine, taken withalanine and glutamic acid help to reduced the amount of swelling in the prostate tissue.

6. Saw palmetto
Saw palmetto is the number one choice when it comes to prostate health. Recent study of American Society for cell biology shows that saw palmetto inhibited prostate cancer cell growth in the test tube. It has been used for a long time as an herb to treat an enlarged prostate gland in men. It may also be used to treat prostate cancer. This herbal remedy has no significant side effects and only rarely causes mild stomach upset or diarrhea.

7. Pumpkin seed extract
Pumpkin seeds contain high amounts of zinc and fatty acids which is necessary for the prostate's health. Pumpkin seed extract helps to tone the bladder muscles, relax the sphincter mechanism and recongest the prostate.

8. Uva ursi
Uva ursi is an evergreen perennial shrub. It has been used since the year 150AD by various civilizations to treat urinary tract infections, kidney problems, Prostate, and bladder dysfunction.

9. Patrinia (Bai jiang cao)
Patrinia helps the body get rid of prostate inflammation and damp heat that exists in the body. In Chinese medicine damp heat in the prostate could be caused by bacteria infection, drugs and other conditions such as a habit of eating hot, spicy or greasy foods.

10. He shou wu
He shou wu contains several derivatives of tetrahydroxystilbene. These antioxidants and anti-inflammatory compounds may act as an estrogen, reducing levels of circulating male hormones such as DHT that fuel the growth of prostate cancer.

11. Astragalus root
Astragalus root is a sprawling perennial legume. The Chinese medicine uses the dried sliced or powdered root of the plant to enhance immune function by increasing the activity of certain white blood cells, which increases the production of antibodies. It also helps to increase the body's resistance to infections, to heal the allergies, and to raise and renew the vitality.

By combining the use of these natural remedies, it will help to raise the levels of free testosterone and promote a strong prostate gland. I hope this information will help in preventing and treating enlarged prostate and prostate cancer caused by testosterone deficiency.
Chinese Food Therapy
The Best Way to prevent, treat your disease, including Obesity 
and restore your health naturally with Chinese diet

Ovarian Cysts And PCOS Elimination

Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

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Traditional Chinese Medicine Herbal Therapy - Popular Herbal Chinese Herbs – Bai Zi Ren (Platycladi Semen)

Kyle J. Norton(Scholar and Master of Nutrients, all right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

              Bai Zi Ren (Platycladi Semen)


Bai Zi Ren is also known as biota seed. The sweet, acrid and neutral herb has been used in TCM to treat insomnia, palpitations, neurasthenia, constipation, weak memory, losing hair, etc as it nourishes the Heart, moistens the Intestines, Promotes bowel movement, etc. by enhancing the functions of heart, spleen. channels.

Ingredeients
1. Fat
2. Evaporating oil
3. Saponin
4. Etc.

Health Benefits
1. Anti-allergic effect
Lambertianic acid found in the leaves of Thuja orientalis (Bai zi Ren) may contain the property in treating allergym as it inhibited the production of interleukin-6 (IL-6), PGD(2) and LTC(4), the expression of COX-2 and the degranulation of β-hexosaminidase in the PMA plus calcimycin-induced BMMCs in mouse, according to the study of “Anti-allergic effect of lambertianic acid from Thuja orientalis in mouse bone marrow-derived mast cells” by Chae HS, Chin YW.(1).

2. Anti-inflammatory activities
Chloroform fraction (CHL) and pure compounds of Franco (LPO) has worked together in exhibiting the anti inalmmatory effect as CHL and its components (hinokiol and acacetin) on 5-LOX enhaces the anti-inflammatory activity of LPO, according to the study of “The anti-inflammatory activities of an extract and compounds isolated from Platycladus orientalis (Linnaeus) Franco in vitro and ex vivo” by Fan SY, Zeng HW, Pei YH, Li L, Ye J, Pan YX, Zhang JG, Yuan X, Zhang WD(2).

3. Anti -neurotoxicity
Thuja orientalis (Bai Zi Zen) leaves (TOFE) has exerted the ability of protecting SH-SY5Y cells from 6-OHDA through the downregulation of OS and mitochondrial-mediated apoptosis, and decreasing the phosphorylation of extracellular signal-regulated kinase (pERK), as it may be cosidered as a potential source in treatingParkinson’s disease (PD), according to the study of “Protective effects of standardized Thuja orientalis leaves against 6-hydroxydopamine-induced neurotoxicity in SH-SY5Y cells” by Ju MS, Lee P, Kim HG, Lee KY, Hur J, Cho SH, Sung SH, Oh MS.(3).

4. Anti malaria and Japanese encephalitis
Ethanolic and acetone extracts of Nerium indicum and Thuja orientelis has exerted the ability in larviciding for both types of mosquito larvae, thus reducing the risk of malaria and Japanese encephalitis vector, according to the study of “Larvicidal potential of Nerium indicum and Thuja oriertelis extracts against malaria and Japanese encephalitis vector” by Sharma P, Mohan L, Srivastava CN.(4).

5. Ect.

Side effects
1. Bai Zi Ren may cause clonic seizures such as rhythmic jerking movements of the arms and legs(a)
2. Do not use the herb if you are pregnant and breast feeding with out approval by the related field specialist
3. No Other side effect is known


Chinese Food Therapy
The Best Way to prevent, treat your disease, including Obesity 
and restore your health naturally with Chinese diet

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Super foods LibraryEat Yourself Healthy With The Best of the Best Nature Has to Offer

Sources
(1) http://www.ncbi.nlm.nih.gov/pubmed/21854102
(2) http://www.ncbi.nlm.nih.gov/pubmed/21619922
(3) http://www.ncbi.nlm.nih.gov/pubmed/20040370
(a) http://www.mdidea.com/products/proper/proper073research.html

The Obesity's Article: Lose Weight with Foods Substitution

Kyle J. Norton(Scholar and Master of Nutrients, all right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

For a healthy person weight loss is simple: burn more calories than you consume. The healthiest weight is determine by height to weight ratio or Body Mass Index (BMI) and the amount of fat in your body. Unfortunately over 60% of the North American population is considered to be overweight, according to the BMI index. We also have discussed the negative weight loss in the article "Foods make you lose weight". In this article we will to discuss how to lose weight with food substitutions in your diets.

1. Dip fried food is crunchy and tasty, but it contains lots of saturated fat that causes arteries to build up with cholesterol, heart disease and unhealthy weight gain. You can avoid these by steaming, stirring and consuming more cold water fish.

2. Adding one teaspoon of hot pepper and mustard to every meal will raise metabolic rate by as much as 25 percent.

3. Replace the cream in your recipe with low fat sour cream or low fat evaporated milk.

4. Don't smother your baked potato with butter or sour cream. Replace it with salsa or low fat chili.

5. Use olive oil or canola oil instead of animal oils or vegetable oils.

6. Add nuts in your diet. Nuts tend to be high in fat and nutrition, so include them in your diet but do not overdo it.

7. Substitute mungbean paste for butter in peanut butter cookies to lower fat and increase fiber.

8. Serve meat or poultry with cranberry sauce, salsa and skip the gravy.

9. If you don't eat your foods while walking, driving or watching television, you will eat less and enjoy your foods

10. Put spinach on your sandwich instead of lettuce, since spinach is more nutritious.
Chinese Food Therapy

The Best Way to prevent, treat your disease, including Obesity
and restore your health naturally with Chinese diet

Ovarian Cysts And PCOS Elimination

Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Super foods Library, Eat Yourself Healthy With The Best of the Best Nature Has to Offer

The Obesity' Research and Studies - Are standard behavioral weight loss programs effective for young adults

Kyle J. Norton(Scholar and Master of Nutrients, all right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

Obesity is a medical condition of excess body fat accumulated overtime, while overweight is a condition of excess body weight relatively to the height. According to the Body Mass Index(BMI), a BMI between 25 to 29.9 is considered over weight, while a BMI of over 30 is an indication of obesity. According to the statistic, 68% of American population are either overweight or obese.

You can calculate your BMI index BMI= weight (kg)/ height (m2)

In the comparison of the enrollment, attendance, retention and weight losses of young adults in behavioral weight loss (BWL) programs with older participants in the same trials, conducted by Weight Control and Diabetes Research Center, Brown Medical School and The Miriam Hospital(1), found that Young adults represented 7% of the sample, attended significantly fewer sessions than did adults (52 vs 74%, respectively; P<0.001) and were less likely to be retained for the 6-month assessment (67 vs 95%, respectively; P<0.05). Controlling for demographic variables, study and baseline weight, the mean weight losses achieved were significantly less for young adults compared with adults (-4.3 kg (6.3) vs -7.7 kg (7.0), respectively; P<0.05); fewer young adults achieved > or =5% weight loss at 6 months compared with older participants (8/21 (38%) vs 171/277 (62%); P<0.05). After controlling for session attendance, differences in the mean weight loss were not significant (P=0.81). Controlling for baseline values, study and demographics, changes in total physical activity over the initial 6 months of treatment were less for young adults compared with adults, but these differences only approached statistical significance (P=0.07).


Chinese Food Therapy
The Best Way to prevent, treat your disease, including Obesity 
and restore your health naturally with Chinese diet

Ovarian Cysts And PCOS Elimination

Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

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(1) "Are standard behavioral weight loss programs effective for young adults?" by Gokee-LaRose J, Gorin AA, Raynor HA, Laska MN, Jeffery RW, Levy RL, Wing RR., posted in Pubmed



The Holistic prevention, management and treatment of Polycystic Ovarian Syndrome: The Best PCOs Diets for weight loss

Kyle J. Norton(Scholar, Master of Nutrients), all right reserved.
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

                Polycystic Ovarian Syndrome

Polycystic Ovarian Syndrome is defined as endocrinologic diseases among reproductive-age women caused by undeveloped follicles clumping on the ovaries that interferes with the function of the normal ovaries associated with a high risk for metabolic disorder(1) as resulting of enlarged ovaries(2), leading to hormone imbalance(excessive androgen and anti-müllerian hormone (AMH) )(1)(3)(4)(5), induced Hirsutism(6)(7), reproductive disorder(10(12)), risks of type 2 diabetes(9)(10)(11), metabolic syndrome(10)(12) and early cardiovascular disease(8)(13), acne(10)(14), endometrial cancer(18)(19),weight gain and obesity(15)(16)(17). The syndrome effects over 5% of women population or 1 in 20 women.
Unfortunately, according to studies, women with PCOs after the reproductive age, are associated to continuously increase risk of type II diabetes, with no increasingaltered glucose tolerance(20), CVD and hypertension(21).

  The Treatments


In Weight Loss Perspective

Weight loss(733)(734) for obese patients is one of most vital factor to reduce PCOs symptoms(735)(737) and risk of PCOs complications(736)(737). Some researchers found that 5-10% of weight low will improve PCOs features(737) by 25%, including pregnancy(738). How can you lose weight and maintain healthybody for a healthy conception?


      The Best PCOs Diet for weight loss


Most women with PCOs are likely overweight or obese according to BMI index. Most diet plans require the endurance and determination of the participants(750).

1. Complex carbohydrate, low protein and only unsaturated fat diet
This is the one which I have made for my diabetic friends, it works well for her. The plan not only helps to stabilize her blood sugar, but also maintain her weight within the normal range of BMI index. If you would like to try, please first consult with your doctor.
a) No Simple sugar
b) Only eat vegetables (prefer rainbow colors), nuts, seeds and limited intake of fruits containing high amount of sugar such as melon. Fruits only should be eaten as soon as after each meal.
b) Limited intake of protein to 1/3 of the daily amount. Meat must be lean (prefer chicken breast) and eat together with vegetables and fruits to further delay the release of sugar.
c) Only use unsaturated fat as toping. Stirring is allowed with occasional fried foods and others.
d) Drink at least 8 cups of pure water and milk ( prefer one cup of green tea and a cup of morning coffee with no sugar and a little bit milk). Since vegetables contain high amount of fiber, drinking more water can prevent constipation.
e) 1/4 table spoon of cinnamon each in the morning and evening. It is said that cinnamon stimulates the production of insulin(752) and regulates the blood sugar in the blood stream(753).
The diet works well for her in maintaining the healthy weight and stabilizing and lowering the blood sugar. Since she does not have PCOs and problem of infertility, it is for your benefit to check with your doctor before applying.

2. Low carbohydrate and high protein diet (Modified diet with a high-protein,low-glycemic load (30% of daily energy from protein plus low-glycemic-load foods)

This is a type of diet most recommended by dietitian for women with PCOs and wanted to get pregnant.
a) If you have symptoms of PCOs and absence of period, you must see your doctor before attempting any weight loss program.
b) If you have kidney problem, do not attempt this program
c) If you have symptoms of PCOs and irregular menstrual period, this diet plan is helpful
The low carbohydrate diet and high protein diet limits daily intake of amount of carbohydrate and encourages you to take a high amount of protein without restricting yourself to the amount of fat intake. With low levels of carbohydrate in the body, you body needs to burn its fat stores for energy, leading to weight loss(754) and lowering the levels of asting LDL-cholesterol, HDL-cholesterol, glucose, insulin, free fatty acid, and C-reactive protein concentrations(754). In theory, it works well for women with PCOs because by suppressing the levels of insulin(755)(756), The diet improves ovulation(755) and reduce the levels of testosterone(756). It is also recommended that you also engage in moderate exercise to improved the physical fitness level of healthy, pregnant as well(757)(758).



Chinese Food Therapy
The Best Way to prevent, treat your disease, including Obesity
and restore your health naturally with Chinese diet

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Super foods Library, Eat Yourself Healthy With The Best of the Best Nature Has to Offer

References
(1) Adiposity and metabolic dysfunction in polycystic ovary syndrome by Sam S.(PubMed)
(2) A "kiss" before conception: triggering ovulation with kisspeptin-54 may improve IVF by Young SL.(PubMed)
(3.) Androgen hyperfunction and excessive heterosexual hair growth in women, with special attention to the polycystic ovarian syndrome by Lunde O1.(PubMed)
(4) Expression of anti-Müllerian hormone in letrozole rat model of polycystic ovary syndrome by Du DF1, Li XL, Fang F, Du MR.(PubMed)
(5) [Serum levels of anti-muller hormone in women with polycystic ovary syndromeand healthy women of reproductive age].[Article in Bulgarian] by Parahuleva N, Pehlivanov B, Orbecova M, Deneva T, Uchikova E.(PubMed)
(6) [Current opinions on the etiology and pathophysiology of hirsutism].[Article in Polish] by Krysiak R1, Kedzia A, Okopień B.(PubMed)
(7) The clinical evaluation of hirsutism by Somani N1, Harrison S, Bergfeld WF.(PubMed)
(8) Polycystic ovary syndrome and insulin: our understanding in the past, present and future by Mayer SB1, Evans WS, Nestler JE.(PubMed)
(9) Association of mean platelet volume with androgens and insulin resistance in nonobese patients with polycystic ovary syndrome by Dogan BA1, Arduc A2, Tuna MM1, Karakılıc E1, Dagdelen I1, Tutuncu Y1, Berker D1, Guler S1.(PubMed)
(10) Approach to the patient: contraception in women with polycystic ovary syndrome by Yildiz BO1.(PubMed)
(11) Polycystic ovarian syndrome (PCOS): a significant contributor to the overall burden of type 2 diabetes in women by Talbott EO1, Zborowski JV, Rager JR, Kip KE, Xu X, Orchard TJ.(PubMed)
(12) Prevalence of vitamin D deficiency in Slovak women with polycystic ovary syndrome and its relation to metabolic and reproductive abnormalities by Figurová J1, Dravecká I, Javorský M, Petríková J, Lazúrová I.(PubMed)
(13) Role of Insulin Sensitizers on Cardiovascular Risk Factors in Polycystic Ovarian Syndrome: A Meta-Analysis by Thethi TK1, Katalenich B2, Nagireddy P3, Chabbra P4, Kuhadiya N5, Fonseca V1.(PubMed)
(14) Acne in hirsute women by Lumezi BG1, Pupovci HL1, Berisha VL1, Goçi AU2, Gerqari A3.(PubMed)
(15) Obesity and polycystic ovary syndrome by Naderpoor N1, Shorakae S, Joham A, Boyle J, De Courten B, Teede HJ.(PubMed)
(16) Polycystic ovary syndrome: a complex condition with psychological, reproductive and metabolic manifestations that impacts on health across the lifespan by Teede H1, Deeks A, Moran L.(PubMed)
(17) Metabolic Evidence of Diminished Lipid Oxidation in Women With Polycystic Ovary Syndrome. by Whigham LD1, Butz DE2, Dashti H3, Tonelli M3, Johnson LK1, Cook ME2, Porter WP4, Eghbalnia HR5, Markley JL6, Lindheim SR7, Schoeller DA8, Abbott DH9, Assadi-Porter FM10.(PubMed)
(18) Risk of endometrial, ovarian and breast cancer in women with polycystic ovary syndrome: a systematic review and meta-analysis by Barry JA1, Azizia MM1, Hardiman PJ2.(PubMed)
(19) Risk of cancer among women with polycystic ovary syndrome: a Danish cohort study by Gottschau M1, Kjaer SK2, Jensen A1, Munk C1, Mellemkjaer L3.(PubMed)
(20) Polycystic ovary syndrome: metabolic consequences and long-term management by Carmina E1.(PubMed)
(21) Arterial stiffness is increased in asymptomatic nondiabetic postmenopausal women with a polycystic ovary syndrome phenotype by Armeni E1, Stamatelopoulos K, Rizos D, Georgiopoulos G, Kazani M, Kazani A, Kolyviras A, Stellos K, Panoulis K, Alexandrou A, Creatsa M, Papamichael C, Lambrinoudaki I.(PubMed)
(733) [Treatment of PCOS without IVF: weight loss, insulin-sensitizing agents].[Article in French] by Pugeat M1.(PubMed)
(734) A 12-week treatment with the long-acting glucagon-like peptide 1 receptor agonist liraglutide leads to significant weight loss in a subset of obese women with newly diagnosed polycystic ovary syndrome by Jensterle M1, Kravos NA1, Pfeifer M1, Kocjan T1, Janez A1.(PubMed)
(735) Body mass index and gonadotropin hormones (LH & FSH) associate with clinical symptoms among women with polycystic ovary syndrome by Esmaeilzadeh S, Andarieh MG1, Ghadimi R, Delavar MA.(PubMed)
(736) Obesity and polycystic ovary syndrome by Naderpoor N1, Shorakae S, Joham A, Boyle J, De Courten B, Teede HJ.(737)
(737) Polycystic ovary syndrome: a complex condition with psychological, reproductive and metabolic manifestations that impacts on health across the lifespan by Teede H1, Deeks A, Moran L.(PubMed)
(738) A retrospective study of the pregnancy, delivery and neonatal outcome in overweight versus normal weight women with polycystic ovary syndrome by De Frène V1, Vansteelandt S2, T'Sjoen G3, Gerris J4, Somers S4, Vercruysse L4, De Sutter P4.(PubMed)
(739) Carbohydrate(CDC)
(752) Chromium and polyphenols from cinnamon improve insulin sensitivity by Anderson RA1.(PubMed)
(753) The potential of cinnamon to reduce blood glucose levels in patients with type 2 diabetes and insulin resistance by Kirkham S1, Akilen R, Sharma S, Tsiami A.(PubMed)
(754) Effect of an energy-restricted, high-protein, low-fat diet relative to a conventional high-carbohydrate, low-fat diet on weight loss, body composition, nutritional status, and markers of cardiovascular health in obese women by Noakes M1, Keogh JB, Foster PR, Clifton PM.(PubMed)
(755) Diet and lifestyle in the prevention of ovulatory disorder infertility by Chavarro JE1, Rich-Edwards JW, Rosner BA, Willett WC.(PubMed)
(756) Beneficial effects of a high-protein, low-glycemic-load hypocaloric diet in overweight and obese women with polycystic ovary syndrome: a randomized controlled intervention study by Mehrabani HH1, Salehpour S, Amiri Z, Farahani SJ, Meyer BJ, Tahbaz F.(PubMed)
(757) 30(+) years of exercise in pregnancy by Lotgering FK1.(PubMed)
(758) Effect of a physical exercise program during pregnancy on uteroplacental and fetal blood flow and fetal growth: a randomized controlled trial by de Oliveria Melo AS1, Silva JL, Tavares JS, Barros VO, Leite DF, Amorim MM.(PubMed)

Most Common Diseases of 50Plus:The Research and Studies of Ischemic heart disease - The Symptoms

Kyle J. Norton(Scholar and Master of Nutrients, all right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

                 Cardiovascular Disease 


Cardiovascular disease is defined as medical conditions affecting the cardiovascular system, including heart, blood vessels(arteries and veins).
Beside cancer, heart disease kills more than 2,000 Americans everyday. Approximately 60 million Americans have heart disease.
There are many causes of heart diseases. Most of heart diseases are caused by high blood pressure contributes to hardening of the arteries. High levels of bad cholesterol (LDL) build up in the arteries as a result of uncontrolled diet with high levels of saturated fat and trans fat. All these add to the formation of atherosclerosis lesions and eventually arterial blockage or anything that serves to damage the inner lining of blood vessels and impedes the transportation of oxygen and nutrition to the heart can be defined as a risk of heart disease.

                                 Ischemic heart disease
Ischemic heart disease is defined as a condition of reduced blood supply of the heart muscle, as a result of coronary artery disease caused by plague building up in the arteries.

                               The Symptoms

Reduction of blood flow to the heart muscle may be resulting in a number of symptoms, which can vary in intensity among individuals.

1. Angina pectoris
Angina pectoris is defined as a condition of chest pain as a result of lack of blood supply to the heart muscle, due to obstruction or spasm of the coronary arteries of the heart's blood vessels.

2. Acute coronary syndrome
Acute coronary syndrome is defined as any group of symptoms caused by obstruction of the coronary arteries, mostly due to ST elevation myocardial infarction (30%), non ST elevation myocardial infarction (25%), or unstable angina (38%)
a. ST elevation myocardial infarction
St elevation myocardial infarction is a heart attack as a result of blockage of blood flow to the heart long enough time to cause damage or die of the heart muscle.
b. Unstable angina
Unstable angina, a type of acute coronary syndrome is a medical condition as a result of the heart not enough blood flow and oxygen cause of heart attack
c. Myocardial infarction
Myocardial infarction, a severe chest pain can not be relieved by rest as a result of acute heart damage.
Some researchers suggested that Ischemia refers to inadequate supply of oxygen and metabolic substrate to an organ. The term myocardial ischemia covers a heterogeneous group of clinical syndromes, globally called ischemic heart disease, which includes chronic stable angina at one end of the spectrum and acutemyocardial infarction at the other end. Between these two extremes, there is a broad myriad of intermediate syndromes, all having in common a mismatch between oxygen demand and supply. Ischemic heart disease is the leading cause of all morbidity and mortality in the United States(1).

3. Heart failure
Heart failure is defined as a condition in which the heart can't pump and/or fill enough blood to meet the body's needs due to weakness of the heart muscle of that can lead to difficulty in breathing or swelling of the extremities.

4. Fatigue and depression
Disease stage was neither associated with symptoms of fatigue (P=0.99) nor depression (P=0.29) at 12 months. In contrast, type-D personality was shown to predict both symptoms of fatigue [odds ratio (OR)=2.96; 95% confidence interval (CI): 1.92-4.58, P<0.001] and depression (OR=4.91; 95% CI: 3.16-7.65, P<0.001) at follow-up, but type-D personality(2)

5. Other symptoms include
a. Clammy skin
b. Nausea with or without vomiting
c. Pain in the neck or jaw
d. difficulty in breathing or rapid breathing
e. swelling of the extremities
f. Pain on Shoulder or arm
g. Etc.
6. Etc.