Medical Advisor Journals

Wednesday, June 15, 2016

Traditional Chinese Medicine Herbal Therapy - Popular Chinese Herbs – Bi Ma Zi (Semen Ricinui communis)

Bi Ma Zi (Semen Ricinui communis)

Bi Ma Zi is also known as castor bean. The acrid, bitter, neutral and toxic herb has been used in TCM to treat abscess, tuberculosis of lymph nodes of the neck, acute and chronic pharyngitis, edema, ascites, constipation, nose bleeding and cough with phlegm and asthma. etc. as it expels dampness, reduces edema, dispels toxicity, carbuncles etc. by enhancing the function of liver, spleen, lung channels.

Ingredients
1. Tinricinolein
2. Ricinoleic acid
3. Linoleic acid
4. Sitosterol
5. Ricinine
6. Ricin D
7. Galactose-binding proteins
8. Phosphatidylethanolamine
9. Phosphatidylcholine
10. Apigenin
11. Chlorogenic acid
12. Etc.

Health benefit
1. Detoxification
In the evacuation of castor bean and its detoxification effects found that castor bean simultaneously induces the production of tannase and phytase by Paecilomyces variotii; both enzymes have high levels of activity and have the potential to be used in feedstuffs because they decrease overall anti-nutritional factors, according to the study of “Detoxification of castor bean residues and the simultaneous production of tannase and phytase by solid-state fermentation using Paecilomyces variotii” by Madeira JV Jr, Macedo JA, Macedo GA.(1).

2. Contraceptive potentials
In the investigation of Ricinui communis and it effects of female infertility in guinea pigs, found that Castor bean processes anti-implantation and abortifacient effects by prolonging the oestrus cycle of guinea pigs, according to the study of “Antifertility activity of Ricinus communis seed in female guinea pigs” by Makonnen E, Zerihun L, Assefa G, Rostom AA.(2).

3. Central nervous system stimulant effects
In the study of The extract of the pericarp of castor bean (Ricinus communis) and it effects in central nervous system found that At lower doses the extract improved memory consolidation and showed some neuroleptic-like properties, such as a decrease in exploratory behavior and catalepsy. The memory-improving effect and the seizure-eliciting properties of the extract were also observed with the administration of ricinine, a neutral alkaloid isolated from the extract, according to the study of “Pharmacological evaluation of ricinine, a central nervous system stimulant isolated from Ricinus communis’ by Ferraz AC, Angelucci ME, Da Costa ML, Batista IR, De Oliveira BH, Da Cunha C.(3).

4. Wound healing
In the evaluation of The biocompatibility of polyurethane resin-implants derived from castor bean (Ricinus communis) and it effects in would healing found that after week 6 of adjacent to the implants, the fibrous capsule was thinner and the tested area was almost totally covered with bone, which in several places was in close contact with the implants, according to the study of “Histologic and histometric evaluation of rat alveolar wound healing around polyurethane resin implants” by Carvalho TL, Araújo CA, Teófilo JM, Brentegani LG.(4).

5. Etc.

Side effects
1. Contraindicated during pregnancy and in cases of loose stool.
2. Overdoses may be cause severe poisoning in an adult, according to the study of “Ricinus communis Intoxications in Human and Veterinary Medicine-A Summary of Real Cases” by Worbs S, Köhler K, Pauly D, Avondet MA, Schaer M, Dorner MB, Dorner BG.(a)
3. Castor bean can induced allergic effects in certain people, according to the study of “Allergy to castor bean. II. Identification of the major allergens in castor bean seeds” by Thorpe SC, Kemeny DM, Panzani RC, McGurl B, Lord M.(b)
4. Etc.

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and restore your health naturally with Chinese diet

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Sources
(1) http://www.ncbi.nlm.nih.gov/pubmed/21612916
(2) http://www.ncbi.nlm.nih.gov/pubmed/10750521
(3) http://www.ncbi.nlm.nih.gov/pubmed/10418776
(4) http://www.ncbi.nlm.nih.gov/pubmed/9151174
(a) http://www.ncbi.nlm.nih.gov/pubmed/22069699
(b) http://www.ncbi.nlm.nih.gov/pubmed/3392372

Herbal therapy: Popular Herbal Goldenseal (Hydrastis canadensis)

Kyle J. Norton(Scholar and Master of Nutrients, all right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

Goldenseal (Hydrastis canadensis)
Goldenseal also known as Orange-root is a perennial plant, in the genus Hydrastis, belonging to the family Ranunculaceae, native to native to southeastern Canada and the northeastern United States. The herb has been used in traditional medicine to treat colds & flu, sinus and chest congestion, bladder infections and fungal infections, to promote wound healing, etc,.

Health Benefits
1. H1N1 influenza A
In the evaluation of whether the isoquinoline alkaloid berberine from glodenseal can inhibit the growth of influenza A, found that strong inhibition of production of both mediators and suggest that this effect is distinct from the anti-viral effect. Finally, we asked whether berberine-containing ethanol extracts of goldenseal also inhibit the growth of influenza A and production of inflammatory mediators. We found strong effectiveness at high concentrations, although upon dilution extracts were somewhat less effective than purified berberine, according to "Inhibition of H1N1 influenza A virus growth and induction of inflammatory mediators by the isoquinoline alkaloid berberine and extracts of goldenseal (Hydrastiscanadensis)" by Cecil CE, Davis JM, Cech NB, Laster SM.(1)

2. Carcinogenesis
In the classification of the major alkaloids in goldenseal are berberine, hydrastine, and canadine in Goldenseal root powder and theirs potential for human carcinogenicity found that some evidence of carcinogenic activity of goldensealroot powder in male B6C3F1 mice based on the increased incidences of hepatoblastoma and multiple hepatocellular adenoma, according to "Toxicology and carcinogenesis studies of goldenseal root powder (HydrastisCanadensis) in F344/N rats and B6C3F1 mice (feed studies)" by National Toxicology Program.(2)

3. Antibiotic resistance
In the investigation of new potential sources of antimicrobial agents to Neisseria gonorrhoeae (Ng) resistance found that Extracts of Arctostaphylos uva ursi (kinnikinnick or bearberry), Hydrastis canadensis (goldenseal), Prunus serotina (black cherry), and Rhodiola rosea (roseroot) inhibited the growth of all Ng isolates with minimum inhibitory concentrations of 32 μg/mL, 4 to 32 μg/mL, 16 to >32 μg/mL, and 32 to 64 μg/mL, respectively. Extracts of Acorus americanus (sweet flag), Berberis vulgaris (barberry), Cimicifuga racemosa (black cohosh), Equisetum arvense (field horsetail), Gaultheria procumbens (wintergreen), Ledum groenlandicum (Labrador tea), Ledum palustre (marsh Labrador tea), Oenothera biennis (common evening primrose), Sambucus nigra (elderberry), and Zanthoxylum americanum (prickly ash) had weak or no antimicrobial activity against the Ng isolates with minimum inhibitory concentrations ≥256 μg/mL, according to "Extracts of Canadian first nations medicinal plants, used as natural products, inhibit neisseria gonorrhoeae isolates with different antibiotic resistance profiles" by Cybulska P, Thakur SD, Foster BC, Scott IM, Leduc RI, Arnason JT, Dillon JA.(3)

4. Antibacterial activity
In the identification of Goldenseal (Hydrastis canadensis L.) effect on inflammation and infection found that extracts from the aerial portions of H. canadensis contain efflux pump inhibitors, while efflux pump inhibitory activity was not observed for the root extract. The three most abundant H. canadensis alkaloids, berberine, hydrastine, and canadine, are not responsible for the efflux pump inhibitory activity of the extracts from H. canadensis aerial portions. according to "Goldenseal(Hydrastis canadensis L.) extracts synergistically enhance the antibacterial activity of berberine via efflux pump inhibition" by Ettefagh KA, Burns JT, Junio HA, Kaatz GW, Cech NB.(4)

5. Liver cancer
In observation of ethanolic extract of Hydrastis canadensis and its anti-cancer potentials against p-dimethylaminoazobenzene (p-DAB) induced hepatocarcinogenesis in mice, found that acritical analysis of results of these studies suggested anti-cancer potentials of the drug suitable for use as a supportive complementary medicine in liver cancer, according to "Anti-carcinogenic potentials of a plant extract (Hydrastis canadensis): I. Evidence from in vivo studies in mice (Mus musculus)" by Karmakar SR, Biswas SJ, Khuda-Bukhsh AR.(5)

6. Cytostatic agent
In the analyzing isoquinoline alkaloid berberine found in plants such as goldenseal(Hydrastis canadensis) and its exhibiting antiproliferative and tumoricidal properties found that Berberine displays multiphasic effects in these malignant cell lines, which are correlated with the concentration and intracellular distribution of this alkaloid. These results help explain some of the conflicting information in the literature regarding the effects of berberine, and suggest that its use in clinical development may be more as a cytostatic agent than a cytotoxic compound, according to "Different concentrations of berberine result in distinct cellular localization patterns and cell cycle effects in a melanoma cell line" by Serafim TL, Oliveira PJ, Sardao VA, Perkins E, Parke D, Holy J.(6)

7. Cholesterol
In the study of berberine (BBR), an alkaloid isolated from Goldenseal as a unique cholesterol-lowering drug that upregulates hepatic low density lipoprotein receptor (LDLR) found that ubstantial evidence to show that goldenseal contains natural MDR1 antagonist(s) that accentuate the upregulatory effect of BBR on LDLR mRNA expression. These new findings identify goldenseal as a natural LDL-c-lowering agent, and our studies provide a molecular basis for the mechanisms of action, according to "The medicinal plant goldenseal is a natural LDL-lowering agent with multiple bioactive components and new action mechanisms" by Abidi P, Chen W, Kraemer FB, Li H, Liu J.(7)

8. Antimicrobial activities
In the assessment of Two new C-methyl flavonoids, 6,8-di- C-methylluteolin 7-methyl ether (1) and 6- C-methylluteolin 7-methyl ether (2), were isolated from a commercially available sample of the roots of Hydrastis canadensis, along with seven known compounds, berberine (3), beta-hydrastine (4), canadine (5), canadaline (6), isocorypalmine (7), canadinic acid (8), and beta-sitosterol 3- O-beta- D-glucoside (9). and intesting theirs effect on microbial activities found that berberine (3) and, to a lesser extent, 1 and 2, showed antimicrobial activity when evaluated against the oral pathogens Streptococcus mutans and Fusobacterium nucleatum. Berberine (3) exhibited an additive antimicrobial effect when tested against S. mutans in combination with 1, according to "Antimicrobial constituents from goldenseal (the Rhizomes of Hydrastis canadensis) against selected oral pathogens" by Hwang BY, Roberts SK, Chadwick LR, Wu CD, Kinghorn AD(8)

9. Cardiovascular effects
In the researches of Berberine, is an alkaloid from Hydrastis canadensis L., Chinese herb Huanglian and its cardiovascular effects found that Berberine has been shown to prolong the duration of ventricular action potential. Its vasodilator activity has been attributed to multiple cellular mechanisms. The cardiovascular effects of berberine suggest its possible clinical usefulness in the treatment of arrhythmias and/or heart failure, according to "Cardiovascular actions of berberine" by Lau CW, Yao XQ, Chen ZY, Ko WH, Huang Y.(9)

10. Immune stimulant
In the demonstration of the immune stimulant of Goldenseal (Hydrastiscanadenisis) is a native American medicinal plant used as an . Astragalus (Astragalus membranaceus) is a widely used herbal product in China, found that both goldenseal and Astragalus exhibit abilities to modulate macrophage responses during stimulation. Therefore, it is hypothesized that their historical use as therapeutic agents may be due to reduction in the pro-inflammatory response that indirectly leads to limiting of clinical symptoms during infection. Both products differ in their immune stimulatory patterns, offering insight into differential use and therapeutic potential of these products to regulate macrophage immune responses and activation events, according to "Immune modulation of macrophage pro-inflammatory response by goldenseal and Astragalus extracts" by Clement-Kruzel S, Hwang SA, Kruzel MC, Dasgupta A, Actor JK.(10)

11. Relaxant effects
In the investigation of berberine (anticholinergic, antisecretory, and antimicrobial) and beta-hydrastine (astringent) from Hydrastis or goldenseal and its relaxant effects found that at concentrations between 0.01 and 0.1 microg/ml, potentiated the relaxant effect of isoprenaline on carbachol-precontracted isolated guinea pig trachea. These data, which are insufficient to draw definite mechanistic conclusions, indicate that the aforementioned alkaloids may act by interacting with adrenergic and adenosinic receptors "Relaxant effects of Hydrastis canadensis L. and its major alkaloids on guinea pig isolated trachea" by Abdel-Haq H, Cometa MF, Palmery M, Leone MG, Silvestrini B, Saso L.(11)

12. Etc.

Side effects
1. The herb may cause allergic effect
2. Overdoses may cause nausea, vomiting, etc.
3. Do not use the herb if you are pregnant without approval from related field specialist
4. Do not use goldenseal in new born
5. Etc.

Chinese Food Therapy
The Best Way to prevent, treat your disease, including Obesity
and restore your health naturally with Chinese diet

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Super foods Library, Eat Yourself Healthy With The Best of the Best Nature Has to Offer
Sources
(1) http://www.ncbi.nlm.nih.gov/pubmed/21683808
(2) http://www.ncbi.nlm.nih.gov/pubmed/21372858
(3) http://www.ncbi.nlm.nih.gov/pubmed/21301385
(4) http://www.ncbi.nlm.nih.gov/pubmed/21157683
(5) http://www.ncbi.nlm.nih.gov/pubmed/20843149
(6) http://www.ncbi.nlm.nih.gov/pubmed/17661039
(7) http://www.ncbi.nlm.nih.gov/pubmed/16885565
(8) http://www.ncbi.nlm.nih.gov/pubmed/12898417
(9) http://www.ncbi.nlm.nih.gov/pubmed/11607041
(10) http://www.ncbi.nlm.nih.gov/pubmed/18800897
(11) http://www.ncbi.nlm.nih.gov/pubmed/11129501

The Delicious Smoothie of Curcumion, Aloe Vera juice and Grape for Prevention and Treatment of Rosacea

Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.

Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post

Nominated for shorty award over last 4 years

Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

The smoothie for prevention and treatment of Rosacea

Yield: 2 servings (about 8 ounces each)

1 1/2 cups blueberry

1 tsp curcumin

1 cup green tea drink (Make from 4 grams of green tea and a cup of hot water lipped for 5 minutes. Set aside for cooling to room temperature)

1. Place all ingredients in a blender and puree about 1 minute

2. Blend on high speed about 1 minute or until the mixture is thick and the ice is well crushed.

3. Serve immediately

The finding of a natural source for treatment of Rosacea has been running into many obstacles, many ingredients showed initially with promising result in animal studies have not produced same potentials in large sample size and mutli centers human trials.

Rosacea is a chronic inflammatory condition with redness or blushing facial skin. According to the University of Louisville, licorice, green tea, pomegranate, turmeric may be sued for treatment of Rosacea, due to its powerful anti inflammatory effect(1).

Dr. Wu J said, ".....active ingredients, anti-inflammatory properties, clinical effects, and therapeutic potential(rosacea, atopic dermatitis, sensitive and irritated skin, drug-induced skin eruptions, and psoriasis) of colloidal oatmeal, feverfew, licorice, aloe vera, chamomile, and turmeric"(2).

Recent studies by some renowned institutions suggested that Curcumin(5), Aloe Vera juice(7) and blueberry(4) may be the next generation of ingredient extracted from natural sources for reduced risk and treatment of Rosacea.

Resveratrol, a phytochemical in the class of Stilbenoids, found abundantly in blueberry and grape also exhibited anti inflammatory effect against pro inflammatory cytokines(3). According to the investigated the effect of resveratrol on skin lesion, in an atopic dermatitis (AD) mouse model, showed that the phytochemical inhibited the prto inflammatory pathways against skin diseases through modulating the HMGB1 protein expression, a cytokine mediator of inflammation(4).

Curcumin, is a major chemical constituent found in turmeric, which is a perennial plant in the genus Curcuma, belongings to the family Zingiberaceae, native to tropical South Asia. According to the joint study lead by the Stony Brook University, the antioxidant inhibited two inflammatory diseases, periodontitis and rosacea, through inflammatory mediators expression(5).

In fact, Dr. Zhang Y and professors at the State University of New York at Stony Brook said, "Tetracyclines (TCs), (having uniquely modified curcumin as a "core" molecule), are known inhibitors of mammalian-derived MMPs, and non-antibiotic formulations of Doxycycline are FDA-approved to treat periodontitis and the chronic inflammatory skin disease, rosacea"(6).

Aloe Vera is species of succulent plant in the genus Aloe, belonging to the Family Xanthorrhoeaceae, native to Sudan. It has become very popular for commercial cultivation due to its health benefits. According to the University of Pretoria, the herb has been used in treatment of skin disorders, through ts moisturizing and anti-inflammatory effects in modulating the IgE levels of mouse model of atopic dermatitis (AD)(7).

Dr. Benson KF and colleagues in the Aloe vera-based extract of Nerium oleander leaves against skin diseases, said, "NAE-8(®), a novel component of a commercial cosmetic product, showed beneficial antioxidant protection in several cellular models, without the induction of leukocyte activation and secretion of inflammatory cytokines"(8).

Taking altogether, The combination of Curcumin, Aloe Vera juice and Grape may offer the potential effect not only in prevention of the onset and treatment of Rosacea.
People who are at increased risk of Pyoderma gangrenosum are wise to drink at least one serving daily. People with Rosacea, should drink the juice as much as they can, depending to the toleration of digestive system.

Made From Fresh Fruits And Vegetable Recipes
Secret To A Vibrant And Healthy Lifestyle
That You Can Find Easily At The Comfort Of Your Kitchen.

All Forms of Arthritis are Curable
You Can Eliminate Osteoarthritis
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References

(1) Innovations in natural ingredients and their use in skin care by Fowler JF Jr1, Woolery-Lloyd H, Waldorf H, Saini R.(PubMed)

(2) Anti-inflammatory ingredients by Wu J1.(PubMed)

(3) One-year supplementation with a grape extract containing resveratrol modulates inflammatory-related microRNAs and cytokines expression in peripheral blood mononuclear cells of type 2 diabetes and hypertensive patients with coronary artery disease by Tomé-Carneiro J1, Larrosa M, Yáñez-Gascón MJ, Dávalos A, Gil-Zamorano J, Gonzálvez M, García-Almagro FJ, Ruiz Ros JA, Tomás-Barberán FA, Espín JC, García-Conesa MT.(PubMed)

(4) Resveratrol attenuates HMGB1 signaling and inflammation in house dust mite-induced atopic dermatitis in mice by Karuppagounder V, Arumugam S, Thandavarayan RA, Pitchaimani V, Sreedhar R, Afrin R, Harima M, Suzuki H, Nomoto M, Miyashita S,Suzuki K, Watanabe K.(PubMed)

(5) A novel chemically modified curcumin reduces severity of experimental periodontal disease in rats: initial observations by Elburki MS1, Rossa C2, Guimaraes MR2, Goodenough M1, Lee HM1, Curylofo FA2, Zhang Y3, Johnson F3, Golub LM1(PubMed)

(6) Design, synthesis and biological activity of new polyenolic inhibitors of matrix metalloproteinases: a focus on chemically-modified curcumins. by Zhang Y1, Gu Y, Lee HM, Hambardjieva E, Vranková K, Golub LM, Johnson F.(PubMed)

(7) A comparison of the leaf gel extracts of Aloe ferox and Aloe vera in the topical treatment of atopic dermatitis in Balb/c mice by Finberg MJ1, Muntingh GL1, van Rensburg CE2.(PubMed)

(8) Antioxidant, anti-inflammatory, anti-apoptotic, and skin regenerative properties of an Aloe vera-based extract of Nerium oleander leaves (nae-8(®)) by Benson KF1, Newman RA2, Jensen GS1.(PubMed)

Most Common Diseases of Men of 50Plus - Erectile Dysfunction Prevention and Treatment - The Herbal Medicine

The Holistic prevention, management and treatment of Polycystic Ovarian Syndrome: The Fertility Herb Licorice

Polycystic Ovarian Syndrome is defined as endocrinologic diseases among reproductive-age women caused by undeveloped follicles clumping on the ovaries that interferes with the function of the normal ovaries associated with a high risk for metabolic disorder(1) as resulting of enlarged ovaries(2), leading to hormone imbalance(excessive androgen and anti-müllerian hormone (AMH) )(1)(3)(4)(5), induced Hirsutism(6)(7), reproductive disorder(10(12)), risks of type 2 diabetes(9)(10)(11), metabolic syndrome(10)(12) and early cardiovascular disease(8)(13), acne(10)(14), endometrial cancer(18)(19),weight gain and obesity(15)(16)(17). The syndrome effects over 5% of women population or 1 in 20 women.
Unfortunately, according to studies, women with PCOs after the reproductive age, are associated to continuously increase risk of type II diabetes, with no increasingaltered glucose tolerance(20), CVD and hypertension(21).

The prevention and management In Herbal Medicine

Polycystic ovary syndrome (PCOS) is unpreventable in Western medicine. Early diagnosis and treatment may reduce risk of its complications, including infertility, metabolic syndrome, obesity, diabetes, cardiovascular diseases, stroke, etc.
Reduce fat intake less than 30% of total calories with a low proportion of saturated fat and high in fiber from predominantly low-glycaemic-index-carbohydrate foods for patients with PCOs(827a). Calorie intake should be distributed between several meals per day with restricted intake of snacks and drinks(828).

The Fertility Herb: Licorice

See the common herbs used for treatment of PCO

[Gan Cao is also known as Licorice root. The sweet and neutral herb has been used in TCM as anti allergy(856), anti inflammation(855), anti ulcer(857), anti convulsion(858), oxidative stress(858) and to treat stomach weakness, tired and lack of strength, palpitation and short of breath, cough with abundance of phlegm, stomach and solar plexus pain(859), etc., as it tonifies the Spleen, benefits the Qi, moistens the Lungs, calms cough, deaf or acute pain, by enhancing all 12 channels(859). Licorice, in a review of 33 studies of herbal medicine for the management of polycystic ovary syndrome (PCOS), showed a stronge evidences in improved metabolic hormone profile and improved fertility outcomes and regulation of ovulation and inhibition of hyperandrogenism in PCOS(860). In model rats experiment, Ganshao Paste (CGP), also decreased serum levels of LH, T, and FSH and increased of serum estradiol (E2), and progesterone (P)(861)(860)(865). According to University of Natural Resources and Life Sciences Vienna, licorice may have a potential effect on metabolic syndrome(862) in women with PCOs.]

2. Blow flow
Licorice improves the blood flow in the body by exerting its anti thrombosis(983) and inhibiting the levels of bad cholesterol(984)(985) and triglyceride levels(985) and increasing HDL-cholesterol content(984) in reduced risk of cardiovascular disease(985) and blood stagnation(897) in the abdominal region induced induced infertility(986).

3. Glycyrrhizin
Glycyrrhizin, one of main ingredient from licorice, exhibited anti inflammatory effect pharmacologically in treatment of inflammatory diseases(988)(989)(990), lowered high serum testosterone levels in oligomenorrheic or amenorrheic women, and induced conception in some women(991). As antioxidant, the phytochemical also inhibit irregular cell growth(992)(993) and microbial invasion(994)(995) causes of cancers(992)(993) and infection and inflammation(994)(995) respectively. in adrenocortical function and behavour, it also regulated the levels of cortisol(996), induced by over production of serotonin cause of hormone imbalance(997).

4. Phytoestrogen
See phytoestrogen in black cohosh
[Phytoestrogen found it balck cohosh showed to occupy the estrogen receptor sites in women body(908), through it antiestrogenic and extrogenic effects(909), to induce hormone balancing may result in improving the chance of ovulation and fertility(910)(911)].

5. Lecithin
Lecithin is a fat like substance called a phospholipid improved lipid transfer, cholesterol efflux, HDL genesis and and remodeling at the blood-brain barrier (BBB)(998). against cells from oxidation surrounding the brain(999), in reducing psychotic symptoms(1002) such as stress(1000)(1001), and depression(1002).

Side effects
1. It may raise blood pressure(1003)(1004(1006)
2. Long term usage of large dosage can also cause edema(1004)(1006) and hypokalemia(1004)(1005)(1006).
3. Overdose can be toxic(106), in inducing rhabdomyolysis or myoglobinuria(1006).
4. Etc.

Chinese Food Therapy
The Best Way to prevent, treat your disease, including Obesity
and restore your health naturally with Chinese diet

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Super foods Library, Eat Yourself Healthy With The Best of the Best Nature Has to Offer

References
(1) Adiposity and metabolic dysfunction in polycystic ovary syndrome by Sam S.(PubMed)
(2) A "kiss" before conception: triggering ovulation with kisspeptin-54 may improve IVF by Young SL.(PubMed)
(3.) Androgen hyperfunction and excessive heterosexual hair growth in women, with special attention to the polycystic ovarian syndrome by Lunde O1.(PubMed)
(4) Expression of anti-Müllerian hormone in letrozole rat model of polycystic ovary syndrome by Du DF1, Li XL, Fang F, Du MR.(PubMed)
(5) [Serum levels of anti-muller hormone in women with polycystic ovary syndromeand healthy women of reproductive age].[Article in Bulgarian] by Parahuleva N, Pehlivanov B, Orbecova M, Deneva T, Uchikova E.(PubMed)
(6) [Current opinions on the etiology and pathophysiology of hirsutism].[Article in Polish] by Krysiak R1, Kedzia A, Okopień B.(PubMed)
(7) The clinical evaluation of hirsutism by Somani N1, Harrison S, Bergfeld WF.(PubMed)
(8) Polycystic ovary syndrome and insulin: our understanding in the past, present and future by Mayer SB1, Evans WS, Nestler JE.(PubMed)
(9) Association of mean platelet volume with androgens and insulin resistance in nonobese patients with polycystic ovary syndrome by Dogan BA1, Arduc A2, Tuna MM1, Karakılıc E1, Dagdelen I1, Tutuncu Y1, Berker D1, Guler S1.(PubMed)
(10) Approach to the patient: contraception in women with polycystic ovary syndrome by Yildiz BO1.(PubMed)
(11) Polycystic ovarian syndrome (PCOS): a significant contributor to the overall burden of type 2 diabetes in women by Talbott EO1, Zborowski JV, Rager JR, Kip KE, Xu X, Orchard TJ.(PubMed)
(12) Prevalence of vitamin D deficiency in Slovak women with polycystic ovary syndrome and its relation to metabolic and reproductive abnormalities by Figurová J1, Dravecká I, Javorský M, Petríková J, Lazúrová I.(PubMed)
(13) Role of Insulin Sensitizers on Cardiovascular Risk Factors in Polycystic Ovarian Syndrome: A Meta-Analysis by Thethi TK1, Katalenich B2, Nagireddy P3, Chabbra P4, Kuhadiya N5, Fonseca V1.(PubMed)
(14) Acne in hirsute women by Lumezi BG1, Pupovci HL1, Berisha VL1, Goçi AU2, Gerqari A3.(PubMed)
(15) Obesity and polycystic ovary syndrome by Naderpoor N1, Shorakae S, Joham A, Boyle J, De Courten B, Teede HJ.(PubMed)
(16) Polycystic ovary syndrome: a complex condition with psychological, reproductive and metabolic manifestations that impacts on health across the lifespan by Teede H1, Deeks A, Moran L.(PubMed)
(17) Metabolic Evidence of Diminished Lipid Oxidation in Women With Polycystic Ovary Syndrome. by Whigham LD1, Butz DE2, Dashti H3, Tonelli M3, Johnson LK1, Cook ME2, Porter WP4, Eghbalnia HR5, Markley JL6, Lindheim SR7, Schoeller DA8, Abbott DH9, Assadi-Porter FM10.(PubMed)
(18) Risk of endometrial, ovarian and breast cancer in women with polycystic ovary syndrome: a systematic review and meta-analysis by Barry JA1, Azizia MM1, Hardiman PJ2.(PubMed)
(19) Risk of cancer among women with polycystic ovary syndrome: a Danish cohort study by Gottschau M1, Kjaer SK2, Jensen A1, Munk C1, Mellemkjaer L3.(PubMed)
(20) Polycystic ovary syndrome: metabolic consequences and long-term management by Carmina E1.(PubMed)
(21) Arterial stiffness is increased in asymptomatic nondiabetic postmenopausal women with a polycystic ovary syndrome phenotype by Armeni E1, Stamatelopoulos K, Rizos D, Georgiopoulos G, Kazani M, Kazani A, Kolyviras A, Stellos K, Panoulis K, Alexandrou A, Creatsa M, Papamichael C, Lambrinoudaki I.(PubMed)
(827a) Diet and nutrition in polycystic ovary syndrome (PCOS): pointers for nutritional management by Farshchi H, Rane A, Love A, Kennedy RL(PubMed)
(828) The optimal diet for women with polycystic ovary syndrome? by Marsh K, Brand-Miller J.(PubMed)
(983) Antithrombotic effect of Glycyrrhizin, a plant-derived thrombin inhibitor by Mendes-Silva W1, Assafim M, Ruta B, Monteiro RQ, Guimarães JA, Zingali RB.(PubMed)
(984) Hypocholesterolaemic and antioxidant effects of Glycyrrhiza glabra (Linn) in rats by Visavadiya NP1, Narasimhacharya AV.(PubMed)
(985) Antiatherosclerotic effects of licorice extract supplementation on hypercholesterolemic patients: increased resistance of LDL to atherogenic modifications, reduced plasma lipid levels, and decreased systolic blood pressureby Fuhrman B1, Volkova N, Kaplan M, Presser D, Attias J, Hayek T, Aviram M.(PubMed)
(986) [Exploration into rules of combined Chinese and Western medical treatment on immune infertility].[Article in Chinese] by Yao DN1, Chen WY, Xiao Y.(PubMed)
(987) [Treatment of irritable bowel syndrome by Chinese medicine and pharmacy: an analysis of data mining on experiences of experts].[Article in Chinese] by Zhang BH1, Gao R, Li ZH, Li BS, Wang FY, Tang XD.(PubMed)
(988) [Pharmacological study of the anti-inflammatory agent glyderinine].[Article in Russian] by Azimov MM, Zakirov UB, Radzhapova ShD.(PubMed)
(989) Glycyrrhizin protects mice against renal ischemia-reperfusion injury through inhibition of apoptosis and inflammation by downregulating p38 mitogen-activated protein kinase signaling by Ye S1, Zhu Y1, Ming Y1, She X1, Liu H1, Ye Q1.(PubMed)
(990) Protective effect of glycyrrhizin, a direct HMGB1 inhibitor, on focal cerebral ischemia/reperfusion-induced inflammation, oxidative stress, and apoptosis in rats by Gong G1, Xiang L2, Yuan L3, Hu L1, Wu W1, Cai L1, Yin L1, Dong H3.(PubMed)
(991) [Effect of shakuyaku-kanzo-to, shakuyaku, kanzo, paeoniflorin, glycyrrhetinic acid and glycyrrhizin on ovarian function in rats].[Article in Japanese] by Takeuchi T1.(PubMed)
(992) Glycyrrhizin induces apoptosis in prostate cancer cell lines DU-145 and LNCaP by Thirugnanam S1, Xu L, Ramaswamy K, Gnanasekar M.(PubMed)
(993) Glycyrrhetic acid (a metabolic substance and aglycon of glycyrrhizin) induces apoptosis in human hepatoma, promyelotic leukemia and stomach cancercells by Hibasami H1, Iwase H, Yoshioka K, Takahashi H.(PubMed)
(994) Glycyrrhizin, an active component of licorice roots, reduces morbidity and mortality of mice infected with lethal doses of influenza virus by Utsunomiya T1, Kobayashi M, Pollard RB, Suzuki F.(PubMed)
(995) Glycyrrhizin stimulates growth of Eubacterium sp. strain GLH, a human intestinal anaerobe by Akao T1, Akao T, Kobashi K.(PubMed)
(996) [Involvement of striatal serotonin in fluoxetine effects on adrenocortical function and behaviour].[Article in Russian] by Shishkina GT, Bulygina VV, Iudina AM, Tolstikova TG, Dygalo NN.(PubMed)
(997) Relationships between androgens, serotonin gene expression and innervation in male macaques by Bethea CL1, Coleman K2, Phu K3, Reddy AP3, Phu A3.(PubMed)
(998) Phospholipid transfer protein is expressed in cerebrovascular endothelial cells and involved in high density lipoprotein biogenesis and remodeling at the blood-brain barrier by Chirackal Manavalan AP1, Kober A, Metso J, Lang I, Becker T, Hasslitzer K, Zandl M, Fanaee-Danesh E, Pippal JB, Sachdev V, Kratky D, Stefulj J, Jauhiainen M, Panzenboeck U.(PubMed)
(999) Alterations in phospholipidomic profile in the brain of mouse model of depression induced by chronic unpredictable stress by Faria R1, Santana MM2, Aveleira CA3, Simões C1, Maciel E1, Melo T1, Santinha D1, Oliveira MM4, Peixoto F5, Domingues P1, Cavadas C2, Domingues MR6.(PubMed)
(1000) Effects of soy lecithin phosphatidic acid and phosphatidylserine complex (PAS) on the endocrine and psychological responses to mental stress by Hellhammer J1, Fries E, Buss C, Engert V, Tuch A, Rutenberg D, Hellhammer D.(PubMed)
(1001) Lecithin:cholesterol acyltransferase deficiency protects against cholesterol-induced hepatic endoplasmic reticulum stress in mice by Hager L1, Li L, Pun H, Liu L, Hossain MA, Maguire GF, Naples M, Baker C, Magomedova L, Tam J, Adeli K, Cummins CL, Connelly PW, Ng DS.(PubMed)
(1002) Altered phospholipid metabolism in schizophrenia: a phosphorus 31 nuclear magnetic resonance spectroscopy study by Weber-Fahr W1, Englisch S, Esser A, Tunc-Skarka N, Meyer-Lindenberg A, Ende G, Zink M.(PubMed)
(1003) Licorice-induced hypertension and syndromes of apparent mineralocorticoid excess by Walker BR1, Edwards CR.(PubMed)
(1004) Gan Cao(Chinese(Complementary and Alternative Healing University)
(1005) Licorice-induced hypokalemia by Mumoli N, Cei M.(PubMed)
(1006) Glycyrrhizic acid toxicity caused by consumption of licorice candy cigars by Johns C1.(PubMed)

The Obesity' Research and Studies -Weight Loss and Very Low Calorie Diet

The Obesity's Weight Loss Recipes: Cucumber in sour cream

Kyle J. Norton(Scholar, Master of Nutrients), all right reserved.
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

Recipe attributed to Company's Coming Salads by Jean Parè

A favorite that is one of easiest
Cucumber, medium size, with peel 3
salt 11/2 tsp. (7 ml)
Sour cream 1 cup (250 ml)
Dill weed 1/2 tsp. (2 ml)
Using a dinner fork, score clean cucumbers from top to bottom all around the outside. Slice thinly. Sprinkle with salt. Stir and allow to stand about 1/2 to 1 hour. Drain well.
Stir dour cream and dill weed together. Pour over cucumbers. Stir to cover all pieces. Serve. If time is short, stir salt into sour cream and dill. Combine with cucumber just before serving to prevent cream from becoming too thin to standing. Serve 12 to 15
Variation: Add 2 tbsp. (30ml) lemon juice. 2 tbsp. (30 ml) parsley and 2 tbsp. (30 ml) granulated sugar.
Chinese Food Therapy
The Best Way to prevent, treat your disease, including Obesity
and restore your health naturally with Chinese diet

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Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

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