Medical Advisor Journals

Thursday, June 16, 2016

Traditional Chinese Medicine Herbal Therapy - Popular Chinese Herbs – Bi Xie (Rhizoma Dioscoreae Hypoglaucae)

1. Anti-Mite activity
Active Demodex folliculorum were selected from patients with moderate to severe Demodex infestation to test for it effects in mite found that Dioscoreae Hypoglaucae kill mites within five minutes, according to the study of “[Anti-mite activities of 25 kinds of traditional Chinese medicines for Demodex folliculorum] [Article in Chinese] by Tian Y, Li CP.(1).

2. Osteoporosis
In the investigation of the decoction of Rhizoma Dioscoreae septemlobae(Pi Xie) (RD) and its effects of osteoporosis found that the decoction of RD can decline the bone turnover and the loss of bone of femur in the ovariectomized rats, according to the study of “[Effects of Dioscorea septemloba on the biomechanical and bone histomorphometric parameters of femur in the ovariectomized rats].[Article in Chinese]” by Xing GS, Lou JS, Yu SL, Wang ZB, Shi YJ.(2).

3. Rheumatoid arthritis
In the evaluation of Methanol extract of Dioscoreae Rhizom and it effects of
found that significantly inhibited the production of TNF-alpha and IL-1beta as well as down-regulating the expression of cyclooxygenase-2 (COX-2) and inducible nitric oxide synthase (iNOS) in IL-1beta- and TNF-alpha-stimulated hFLSCs. MDR also effectively reduced the level of reactive oxygen species (ROS) in these cells, according to the study of “Methanol extract of Dioscoreae Rhizoma inhibits pro-inflammatory cytokines and mediators in the synoviocytes of rheumatoid arthritis” by Kim MJ, Kim HN, Kang KS, Baek NI, Kim DK, Kim YS, Jeon BH, Kim SH.(3).

4. Benign prostatic hyperplasia
In clinical observation of zi yin tong bi formula, including Yam Rhizome and it effects on benign prostatic found hyperplasia found that the formula has improve the symptoms of night urination, degree of dysuria, condition of urinary thread, soreness and weakness in loin and knees, lower abdominal distention, spiritless and general weakness, according to the study of “[Clinical observation on ziyin tongbi decoction in treating benign prostatic hyperplasia].[Article in Chinese]” by Guo J, Song CS, Han Q.(4).

5. Etc.

Side effects
1. Bi Xie may increase in fibrosis in the kidneys and in inflammation in livers, accoring to the study of “Dioscorea villosa (wild yam) induces chronic kidney injury via pro-fibrotic pathways” by Wojcikowski K, Wohlmuth H, Johnson DW, Gobe G.(a)
2. Do not use if you are pregnant or breast feeding with out consulting with the related field specialist
3. Etc.

Chinese Food Therapy
The Best Way to prevent, treat your disease, including Obesity
and restore your health naturally with Chinese diet

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Super foods Library, Eat Yourself Healthy With The Best of the Best Nature Has to Offer

Sources
(1) http://www.ncbi.nlm.nih.gov/pubmed/17326398
(2) http://www.ncbi.nlm.nih.gov/pubmed/18619278
(3) http://www.ncbi.nlm.nih.gov/pubmed/15351318
(4) http://www.ncbi.nlm.nih.gov/pubmed/19317162
(a) http://www.ncbi.nlm.nih.gov/pubmed/18662738

Most Common Diseases of Men of 50Plus - Erectile Dysfunction Prevention and Treatment - The Chinese Herbal Medicine

Phytochemicals in Foods - The Effects of Campesterol

Kyle J. Norton(Scholar and Master of Nutrients, all right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

Campesterol

Campesterol is a phytochemincal in the class of Phytosterols, belonging to the group of Lipids, found abundantly in banana, pomegranate, pepper, coffee, grapefruit, cucumber, onion, oat, potato, etc.

Health benefits
1. Cardiovascular diseases
In the review of the studies published between January 1950 and April 2010 that reported either risk ratios (RR) of CVD in relation to serum sterol concentrations (either absolute or expressed as ratios relative to total cholesterol) or serum sterol concentrations in CVD cases and controls separately, indicated that 17 studies using different designs (four case-control, five nested case-control, three cohort, five cross-sectional) involving 11 182 participants. Eight studies reported RR of CVD and 15 studies reported serum concentrations in CVD cases and controls. Funnel plots showed evidence for publication bias indicating small unpublished studies with non-significant findings. Neither of our meta-analyses suggested any relationship between serum concentrations of sitosterol and campesterol (both absolute concentrations and ratios to cholesterol) and risk of CVD. Our systematic review and meta-analysis did not reveal any evidence of an association between serum concentrations of plant sterols and risk of CVD, according to "Plant sterols and cardiovascular disease: a systematic review and meta-analysis" by Genser B, Silbernagel G, De Backer G, Bruckert E, Carmena R, Chapman MJ, Deanfield J, Descamps OS, Rietzschel ER, Dias KC, März W.(1)

2. Cholesterol
In the investigation of Phytosterols (PSs),a group of plant derived steroid alcohols, with wide occurrence in vegetables and fruits, indicated that Structural resemblance of PSs with cholesterol enables them to displace low-density lipoprotein (LDL) cholesterol in the human intestine. Protective effects of PSs against cardiovascular diseases (CVDs), colon and breast cancer developments have been widely documented. Several reports have been published on the potential dietary intake of common PSs, such as β-sitosterol, stigmasterol andcampesterol, and their safety concerns. Ability of PSs to reduce cholesterol levels and risks associated with heart problems has made them a class of favorite food supplement, according to "Phytosterols: perspectives in human nutrition and clinical therapy' by Choudhary SP, Tran LS.(2)

3. Weight loss
In the assessment of the effects of 2 y of weight loss achieved with various diet regimens on phytosterols (markers of intestinal cholesterol absorption), lanosterol (marker of de novo cholesterol synthesis), and changes in apolipoprotein concentrations, found that a significant upregulation of the markers of cholesterol absorption (campesterol: +16.8%, P < 0.001) and a downregulation of the markers of cholesterol synthesis (lanosterol: -16.5%, P = 0.008) during the active weight-loss phase (first 6 mo, weight loss of 5%, 6%, and 10% in the 3 diet groups, respectively), followed by a rebound (campesterol: -6.2%, P = 0.045; lanosterol: +43.7%, P < 0.001) during the next 18 mo (weight gain of 1%, 1%, and 2% in the 3 diet groups, respectively). HDL cholesterol continuously increased during the study (17.0%, P < 0.001), whereas LDL cholesterol remained constant. At the end of the 24-mo follow-up period, campesterol (P < 0.001) and lanosterol (P = 0.016) amounts were significantly higher than baseline values, according to "Effects of a 2-y dietary weight-loss intervention on cholesterol metabolism in moderately obese men" by Leichtle AB, Helmschrodt C, Ceglarek U, Shai I, Henkin Y, Schwarzfuchs D, Golan R, Gepner Y, Stampfer MJ, Blüher M, Stumvoll M, Thiery J, Fiedler GM.(3)

4. Anti cancers
In the investigation of extract of Typhonium giganteum Engl. (BaiFuzi) by GC-MS, including the four major components [β-sitosterol (40.22%), campesterol (18.45%), n-hexadecanoic acid (9.52%) and (Z,Z)-9,12-octadecadienoic acid (8.15%)] found that the extract caused down-regulation of Bcl-2 expression, and up-regulation of Bax expression. Moreover, caspase-3 and caspase-9 protease activity significantly increased in a dose-dependent manner. Collectively, our results showed that the SFE-CO(2) extract from T. giganteum Engl. tubers induces apoptosis in SMMC-7721 cells involving a ROS-mediated mitochondrial signalling pathway, according to "SFE-CO2 extract from Typhonium giganteum Engl. tubers, induces apoptosis in human hepatoma SMMC-7721 cells involvement of a ROS-mediated mitochondrial pathway" by Li Q, Jiang C, Zu Y, Song Z, Zhang B, Meng X, Qiu W, Zhang L.(4)

5. Lung cancer
In the evaluation of the inhibitory effect of Typhonium blumei (Tb) extract on the viability of different cancer cells and the apoptotic effect of this extract on A549 lung cancer cells, indicated that dibutyl phthalate, α-linolenic acid, phytol,campesterol, stigmasterol and β-sitosterol were the major bioactive ingredients of Tb extract. Although all these compounds had good anti-proliferative effects on A549 cells, campesterol (IC(50)=2.2 μM for 24h treatment) and β-sitosterol (IC(50)=1.9 μM for 24h treatment) displayed the greatest inhibitory activity, according to "Typhonium blumei extract inhibits proliferation of human lung adenocarcinoma A549 cells via induction of cell cycle arrest and apoptosis" by
Hsu HF, Huang KH, Lu KJ, Chiou SJ, Yen JH, Chang CC, Houng JY.(5)

6. Cognitive effects
In the investigation of whether plant sterols in the brain are associated with alterations in brain cholesterol homeostasis and subsequently with brain functions, found that plant sterol accumulation resulted in decreased levels of desmosterol (P<0.01) and 24(S)-hydroxycholesterol (P<0.01) in the hippocampus, the brain region important for learning and memory functions, and increased lanosterol levels (P<0.01) in the cortex. However, Abcg5-/- and Abcg5+/+ displayed no differences in memory functions or in anxiety and mood related behavior. The swimming speed of the Abcg5-/- mice was slightly higher compared to Abcg5+/+ mice (P<0.001), according to "Cerebral accumulation of dietary derivable plant sterols does not interfere with memory and anxiety related behavior in Abcg5-/- mice" by Vanmierlo T, Rutten K, van Vark-van der Zee LC, Friedrichs S, Bloks VW, Blokland A, Ramaekers FC, Sijbrands E, Steinbusch H, Prickaerts J, Kuipers F, Lütjohann D, Mulder M.(6)

7. Antibacterial activity and mutagenicity
In the investigation of leaves of Alchornea triplinervia led to the isolation of the known substances quercetin, quercetin-7-O-beta-D-glucopyranoside, quercetin-3-O-beta-D-glucopyranoside, quercetin-3-O-beta-D-galactopyranoside, quercetin-3-O-alpha-L-arabinopyranoside, amentoflavone, brevifolin carboxylic acid, gallic acid, and methyl gallate from the methanolic extract, and stigmasterol, campesterol, sitosterol, lupeol, friedelan-3-ol, and friedelan-3-one from the chloroform extract, found that the methanolic extract showed antibacterial activity and mutagenicity, and is promising activity against Staphylococcus aureus (MIC = 62.5 microg/mL) and was slightly mutagenic in vitro and in vivo at the highest concentrations tested (1335 mg/kg b.w.), according to "Phenolic compounds in leaves of Alchornea triplinervia: anatomical localization, mutagenicity, and antibacterial activity" by Calvo TR, Demarco D, Santos FV, Moraes HP, Bauab TM, Varanda EA, Cólus IM, Vilegas W.(7)

8. Weight loss, hepatic steatosis, inflammation, and LDL-apoB-100 metabolism
In a 16-week intervention trial of a hypocaloric, low-fat diet plus 10 mg/day ezetimibe (n = 15) versus a hypocaloric, low-fat diet alone (n = 10) on intrahepatic triglyceride (IHTG) content, plasma high sensitivity-C-reactive protein (hs-CRP), adipocytokines, and fetuin-A concentrations and apolipoprotein (apo)B-100 kinetics in obese subjects, found that compared with weight loss alone, ezetimibe plus weight loss significantly (all P < 0.05) decreased IHTG content (-18%), plasma hs-CRP (-53%), interleukin-6 (-24%), LDL cholesterol (-18%), campesterol (-59%), and apoB-100 (-14%) levels, with a significant increase in plasma lathosterol concentrations (+43%). The LDL-apoB-100 concentration also significantly fell with ezetimibe plus weight loss (-12%), chiefly owing to an increase in the corresponding fractional catabolic rate (+29%) and suggested that Addition of ezetimibe to a moderate weight loss diet in obese subjects can significantly improve hepatic steatosis, inflammation, and LDL-apoB-100 metabolism, according to "Effect of ezetimibe on hepatic fat, inflammatory markers, and apolipoprotein B-100 kinetics in insulin-resistant obese subjects on a weight loss diet" by Chan DC, Watts GF, Gan SK, Ooi EM, Barrett PH.(8)

9. Etc.
Chinese Food Therapy
The Best Way to prevent, treat your disease, including Obesity
and restore your health naturally with Chinese diet

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Super foods Library, Eat Yourself Healthy With The Best of the Best Nature Has to Offer
Sources
(1) http://www.ncbi.nlm.nih.gov/pubmed/22334625
(2) http://www.ncbi.nlm.nih.gov/pubmed/21864283
(3) http://www.ncbi.nlm.nih.gov/pubmed/21940598
(4) http://www.ncbi.nlm.nih.gov/pubmed/21959296
(5) http://www.ncbi.nlm.nih.gov/pubmed/21470575
(6) http://www.ncbi.nlm.nih.gov/pubmed/21431910
(7) http://www.ncbi.nlm.nih.gov/pubmed/20839624
(8) http://www.ncbi.nlm.nih.gov/pubmed/20185740

Most Common Diseases of 50Plus:The Research and Studies of Ischemic heart disease - Treatments In herbal medicine perspective

Cardiovascular Disease

Cardiovascular disease is defined as medical conditions affecting the cardiovascular system, including heart, blood vessels(arteries and veins).
Beside cancer, heart disease kills more than 2,000 Americans everyday. Approximately 60 million Americans have heart disease.
There are many causes of heart diseases. Most of heart diseases are caused by high blood pressure contributes to hardening of the arteries. High levels of bad cholesterol (LDL) build up in the arteries as a result of uncontrolled diet with high levels of saturated fat and trans fat. All these add to the formation of atherosclerosis lesions and eventually arterial blockage or anything that serves to damage the inner lining of blood vessels and impedes the transportation of oxygen and nutrition to the heart can be defined as a risk of heart disease.

Ischemic heart disease
Ischemic heart disease is defined as a condition of reduced blood supply of the heart muscle, as a result of coronary artery disease caused by plague building up in the arteries.

The Treatments

In herbal medicine perspective

1. Soybean is the genus Glycine, belongings to the family Fabaceae, one of the legumes that contains twice as much protein per acre as any other major vegetable or grain crop, native to Southeast Asia. Now, it is grown worldwide with suitable climate for commercial profit and a a healthy foods. The herb has been used in traditional medicine for the proper functioning of the bowels, heart, kidney, liver, stomach. etc.
a. Insulin sensitive
Soybean helps to normalize plasma glucose and insulin homeostasis, according to "Increased insulin sensitivity and changes in the expression profile of key insulin regulatory genes and beta cell transcription factors in diabetic KKAy-mice after feeding with a soy bean protein rich diet high in isoflavone content" by Nordentoft I, Jeppesen PB, Hong J, Abudula R, Hermansen K.(67)
b. Cardiovascular diseases
Soy protein reduces reduces the levels of serum lipoprotein, decrease in low-density lipoprotein cholesterol (LDL-C), total cholesterol (TC), LDL-C/high-density lipoprotein cholesterol (HDL-C), triacylglycerol/HDL-C and TC/HDL-Cpostmenopausal women are at risk of cardiovascular disease, according to "Effects of soy bean on serum paraoxonase 1 activity and lipoproteins in hyperlipidemic postmenopausal women" by Shidfar F, Ehramphosh E, Heydari I, Haghighi L, Hosseini S, Shidfar S.(68)
c. Adipogenesis and Adipolysis
Germinated soy bean protein hydrolysates had an effect on inhibition of lipid storage in adypocites and increasing lipolysis, according to "Effect of Germinated Soybean Protein Hydrolysates on Adipogenesis and Adipolysis in 3T3-L1 Cells" by González-Espinosa de Los Monteros LA, Ramón-Gallegos E, Torres-Torres N, Mora-Escobedo R.(69)
d. Antioxidant effects
Extract from Virginia-grown soybean seeds had exerted its antioxidant effect when compared for their total phenolic contents (TPC), oxygen radical absorbance capacity (ORAC), and 2,2-diphenyl-1-picrylhydrazyl radical (DPPH(*)) scavenging activities, according to "Comparison of different strategies for soybeanantioxidant extraction" by Chung H, Ji X, Canning C, Sun S, Zhou K.(70)
e. Diabetes and hypertension
Soybean phenolic-rich extracts has exerted the inhibitory activities of phenolic-rich extracts from soybean on α-amylase, α-glucosidase and angiotensin I converting enzyme (ACE) activities in vitro, according to "Soybean phenolic-rich extracts inhibit key-enzymes linked to type 2 diabetes (α-amylase and α-glucosidase) and hypertension (angiotensin I converting enzyme) in vitro" by Ademiluyi AO, Oboh G.(71).

2. Garlic (Allium sativum) is a species in the onion genus, belonging to family Amaryllidaceae, native to central Asia. It has been used popularly in traditional and Chinese medicine in treating common cold and flu to the Plague, blood pressure cholesterol levels, natural antibiotic, etc.
a. Cholesterol
Eating 4 cloves of garlic a day can cut total CHOLESTEROL by 70%(Fresh or Supplement). The member of the allium family fights poor circulation.The sulfur compound in garlic keep your platelets from clumping together. It helps UNCLOG your Arteries but check with your Doctor if you are taking Blood thinning medications. Cook with both Garlic and onion to fight high blood pressure effectively. Try to take them everyday if you have high blood pressure and Cholesterol.

b. Blood pressure
In the assessment of garlic extract and its effect of hypertension. found that Agedgarlic extract was generally well tolerated and acceptability of trial treatment was high (92%) and aged garlic extract is superior to placebo in lowering systolic blood pressure similarly to current first line medications in patients with treated but uncontrolled hypertension, according to "Aged garlic extract lowers blood pressure in patients with treated but uncontrolled hypertension: a randomised controlled trial" by Ried K, Frank OR, Stocks NP.(72) 7. Atherosclerosis
In the demonstration of aged garlic extract therapy with supplements (AGE+S) and theirs effect on cardiovascular diseases found that CAC progression was significantly lower and TR significantly higher in the AGE+S compared to the placebo group after adjustment of cardiovascular risk factors (p<0.05). Total cholesterol, LDL-C, homocysteine, IgG and IgM autoantibodies to MDA-LDL and apoB-immune complexes were decreased, whereas HDL, OxPL/apoB, and Lp (a) were significantly increased in AGE+S to placebo and concluded that AGE+S is associated with a favorable improvement in oxidative biomarkers, vascular function, and reduced progression of atherosclerosis., according to "Aged garlicextract supplemented with B vitamins, folic acid and L-arginine retards the progression of subclinical atherosclerosis: a randomized clinical trial" by Budoff MJ, Ahmadi N, Gul KM, Liu ST, Flores FR, Tiano J, Takasu J, Miller E, Tsimikas S.(73)

3. Alfalfa
a. Antioxidant
In a study of measurements of pH, water holding capacity, color, oxymyoglobin content, TBARS and oxidation-reduction potential in evaluating the effects of a dietary protein-xanthophylls (PX) concentrate of alfalfa to turkey diets conducted by University of Life Sciences in Lublin, Skromna 8, 20-704 Lublin, (74), researchers found that TBARS and oxidation-reduction potential values suggested that the inclusion of the concentrate to turkey diets acts as an antioxidant in the raw meat.
b. Cholesterol
In a study to test the effect of Alfalfa used in traditional medicine to treat high blood cholesterol conducted by Malinow MR, McLaughlin P, Stafford C.(75), in 3 human volunteers during ingestion of diets containing alfalfa seeds (AS) for 3 weeks, researchers found that Plasma cholesterol concentrations were reduced and No signs of toxicity were detected through serum determinations of multiple parameters. The ingestion of AS in rats decreased the concentration of plasma cholesterol, reduced intestinal absorption of exogenous and endogenous cholesterol, and increased fecal biliary excretion.
c. Hyperlipoproteinemia
In a study of Fifteen patients with hyperlipoproteinemia (HLP), types IIA (n = 8), IIB (n = 3) and IV (n = 4) were given 40 g of heat prepared alfalfa seeds 3 times daily at mealtimes for 8 weeks with otherwise unchanged diet, conducted by Mölgaard J, von Schenck H, Olsson AG.(3), found that patients with type II HLPalfalfa treatment caused after 8 weeks a maximal lowering of pretreatment median values of total plasma cholesterol from 9.58 to 8.00 mmol/l (P less than 0.001) and low density lipoprotein (LDL) cholesterol from 7.69 to 6.33 mmol/l (P less than 0.01), which corresponds to decreases of 17% and 18%, respectively. Maximal decrease was 26% in total cholesterol and 30% in LDL cholesterol. In two patients with hypercholesterolemia the LDL cholesterol decreased less than 5%. Apolipoprotein B decreased in the same period from 2.17 to 1.43 g/l (P less than 0.05) in type II HLP, corresponding to 34% decrease, whereas apolipoprotein A-I did not change. Body weight increased slightly during the first 4 weeks of alfalfatreatment (P less than 0.001) probably because of the caloric content in the alfalfaseeds. After cessation of treatment, all lipoprotein concentrations returned to pretreatment levels. We conclude that alfalfa seeds can be added to the diet to help normalize serum cholesterol concentrations in patients with type II HLP.

4. Ginkgo biloba
a. Hypertension
Ginkgo enhanced endothelium-dependent vasodilation and elevation of the endothelial intracellular Ca(2+) level in SHR, resulting in hypotension, according to the study of "Effects of Ginkgo biloba extract on blood pressure and vascular endothelial response by acetylcholine in spontaneously hypertensive rats" by Kubota Y, Tanaka N, Kagota S, Nakamura K, Kunitomo M, Umegaki K, Shinozuka K.(76)
b. Cardiovascular tissues
Ginkgo biloba extract (EGb) has shown the protection of the cardiovascular tissues against HgCl(2)-induced oxidative damage, according to the study of "Protective effects of Ginkgo biloba extract against mercury(II)-induced cardiovascular oxidative damage in rats" by Tunali-Akbay T, Sener G, Salvarli H, Sehirli O, Yarat A.(77)
c. Hyperlipidemia
Ginkgo biloba leaves (EGB) has demonstrated the activities of limitation of the absorption of cholesterol, inactivation of HMGCoA and favorable regulation of profiles of essential polyunsaturated fatty acid (EFA), according to the study of "Application of GC/MS-based metabonomic profiling in studying the lipid-regulating effects of Ginkgo biloba extract on diet-induced hyperlipidemia in rats" by Zhang Q, Wang GJ, A JY, Wu D, Zhu LL, Ma B,(78).

5. Grape seed extract
Grape Seed Extract is the commercial extracts from whole grape seeds that contains many concentrations, including vitamin E, flavonoids, linoleic acid,oligomeric proanthocyanidins(OPCs), etc..The herb has been used in traditional medicine as antioxidant, anti-inflammatory agents and to treat skin wounds with less scarring, allergies, macular degeneration, arthritis, enhance circulation of blood vessels, lower cholesterol, etc.
a. Antioxidant Activity
in the assessment of phenolic content, antioxidant activity of White and red wines spiked with green tea extract and grape seed extract found that the green teaextract and grape seed extract increased antioxidant activity dose-dependently and the CRTs varied considerably between the Korean and Australian groups, with Koreans preferring wines spiked with green tea extract and Australians showing a preference for wines spiked with grape seed extract, according to "Total Phenolic Content, Antioxidant Activity and Cross-Cultural Consumer Rejection Threshold in White and Red Wines Functionally Enhanced with Catechin-Rich" by Yoo YJ, Saliba A, Prenzler PD, Ryan DM.(79)
b. Atherosclerosis
in the association of consumption of red wine and other polyphenolic compounds and prevention of cardiovascular diseases found that aortic atherosclerosis evaluated as the cholesterol content in aortic tissue was comparable in the control and GSE-dosed females, but it was significantly reduced in the abdominal part of GSE-dosed male compared to the controls (P < 0.05). In conclusion, feeding GSEextract to Watanabe heritable hyperlipidemic (WHHL) rabbits had no significant effects in females but was associated with transient less hypercholesterolemic response to semisynthetic diet, according to "Effects of red grape skin and seedextract supplementation on atherosclerosis in Watanabe heritable hyperlipidemic rabbits" by Frederiksen H, Mortensen A, Schrøder M, Frandsen H, Bysted A, Knuthsen P, Rasmussen SE.(80)

6. Hawthorn
a. Hypotensive effects
In the investigation of Hawthorn (Crataegus laevigata) leaves, flowers and berries used by herbal practitioners in the UK to treat hypertension in conjunction with prescribed drugs indicated that this is the first randomised controlled trial to demonstrate a hypotensive effect of hawthorn in patients with diabetes takin, according to "Hypotensive effects of hawthorn for patients with diabetes taking prescription drugs: a randomised controlled trial" by Walker AF, Marakis G, Simpson E, Hope JL, Robinson PA, Hassanein M, Simpson HC(81)
b. Cardiac effects
In the evaluation of the potential cardiac effects of two alcohol extracts of commercially available hawthorn found that the mechanism of cardiac activity ofhawthorn is via the Na(+),K(+)-ATPase and intracellular calcium concentrations are influenced, according to "A comparison of the effects of commercially availablehawthorn preparations on calcium transients of isolated cardiomyocytes" by Rodriguez ME, Poindexter BJ, Bick RJ, Dasgupta A.(82)
c. Cardiovascular disease
In the analyzing the effect of hawthorn in prevention and protection of cardiovascular disease indicated that these beneficial effects may in part be due to the presence of antioxidant flavonoid components. While a number of studies have been performed to evaluate the clinical efficacy of hawthorn, an international, multicenter, prospective clinical study including a large number of New York Heart Association (NYHA) class II/III heart failure patients is ongoing to test hawthorn's long-term therapeutic effects, according to "Hawthorn: potential roles in cardiovascular disease"by Chang WT, Dao J, Shao ZH.(83)
d. Chronic heart failure
In the assessment of Hawthorn extract usedas an oral treatment option for chronic heart failure, found that Ten trials including 855 patients with chronic heart failure (New York Heart Association classes I to III) provided data that were suitable for meta-analysis. For the physiologic outcome of maximal workload, treatment withhawthorn extract was more beneficial than placebo (WMD (Watt) 5.35, 95% CI 0.71 to 10.00, P < 0.02, n = 380). Exercise tolerance were significantly increased by hawthorn extract (WMD (Watt x min) 122.76, 95% CI 32.74 to 212.78, n = 98). The pressure-heart rate product, an index of cardiac oxygen consumption, also showed a beneficial decrease with hawthorn treatment (WMD (mmHg/min) -19.22, 95% CI -30.46 to -7.98, n = 264). Symptoms such as shortness of breath and fatigue improved significantly with hawthorn treatment as compared with placebo (WMD -5.47, 95% CI -8.68 to -2.26, n = 239), according to "Hawthorn extract for treating chronic heart failure" by Pittler MH, Guo R, Ernst E.(84)
e. Hyperlipemia
in the determination of The Yishoujiangzhi (de-blood-lipid) tablets (composed of Radix Polygori Multiflori, Rhizoma Polygonati, Fructus Lycii, Crataegus Pinnatifida and Cassia Tora) and its effect on Hyperlipemia found that in the treatment of 130 cases of hyperlipemia, achieving an effective rate of 87.0% in lowering serum cholesterol and 80.8% in lowering triglyceride, according to 'Yishou jiangzhi (de-blood-lipid) tablets in the treatment of hyperlipemia" by Guan Y, Zhao S.(85)
7. Etc.

Chinese Food Therapy
The Best Way to prevent, treat your disease, including Obesity
and restore your health naturally with Chinese diet

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Super foods Library, Eat Yourself Healthy With The Best of the Best Nature Has to Offer
Sources
(67) http://www.ncbi.nlm.nih.gov/pubmed/18522411
(68) http://www.ncbi.nlm.nih.gov/pubmed/18608549
(69) http://www.ncbi.nlm.nih.gov/pubmed?term=Effect%20of%20Germinated%20Soybean%20Protein%20Hydrolysates%20on%20Adipogenesis%20and%20Adipolysis%20in%203T3-L1%20Cells
(70) http://www.ncbi.nlm.nih.gov/pubmed/20302378
(71) http://www.ncbi.nlm.nih.gov/pubmed/22005499
(72) http://www.ncbi.nlm.nih.gov/pubmed/20594781
(73) http://www.ncbi.nlm.nih.gov/pubmed/19573556
(74) http://www.ncbi.nlm.nih.gov/pubmed/20580166
(75) http://www.ncbi.nlm.nih.gov/pubmed/7379953
(76) http://www.ncbi.nlm.nih.gov/pubmed/16451753
(77) http://www.ncbi.nlm.nih.gov/pubmed/17072828
(78) http://www.ncbi.nlm.nih.gov/pubmed/19960012
(79) http://www.ncbi.nlm.nih.gov/pubmed/22133028
(80) http://www.ncbi.nlm.nih.gov/pubmed/17441214
(81) http://www.ncbi.nlm.nih.gov/pubmed/16762125
(82) http://www.ncbi.nlm.nih.gov/pubmed/19053860
(83) http://www.ncbi.nlm.nih.gov/pubmed/15844828
(84) http://www.ncbi.nlm.nih.gov/pubmed/18254076
(85) http://www.ncbi.nlm.nih.gov/pubmed/8569253

The Delicious Smoothie of Sweet Potato and Pinapple for Prevention and Treatment of Menstrual Migraines

Kyle J. Norton(Scholar, Master of Nutrients), all right reserved.
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

The smoothie for reduced symptoms and treatment of Menstrual Migraines
Yield: 2 serving (about 8 ounce each)
3/4 cups pineapple
3/4 cup sweet potato
1 cup of rice milk

1. Place all ingredients in a blender and puree about 1 minute
2. Blend on high speed about 1 minute or until the mixture is thick and the ice is well crushed. Add more green tea drink if needed
3. Serve immediately

The finding the natural ingredients for treatment of Menstrual Migraines is considered as a dream of many scientist to replace the long term usage adverse effect of conventional medicine.
Unfortunately, many compounds found effective in initial studying failed to confirm the potential in large sample size and multi center.

Menstrual Migraines is a condition of migraine headache occurred on or between 2 days before the onset of menstruation and the first 3 days of bleeding(1) and associated with increased prostaglandin (PG) levels in the endometrium(2).

Recent studies suggested that scientist in some research centers have found the naturally potential ingredients, such as sweet potato(2), and pineapple(3) for prevention and treatment for Menstrual Migraines.

Dr. Shaik MM, and Dr. Gan SH said, vitamin E (found abundantly in sweet potato)
may be beneficiary for women with menstrual migraine due to it anti prostaglandin (PG) hormone effects(2).
According to Tarbiat Modarres University, in the comparison of the vitamin E and the placebo treatment periods, showed that vitamin E induced significant differences in the pain severity and functional disability scales and symptoms of photophobia, phonophobia, and nausea(3).

Melatonin, found abundantly in pineapple is also associated prevention of menstrual migraine(4). According to the University of Genoa,levels of Nocturnal urinary melatonin excretion was significantly decreased in women with menstrual migraines throughout an ovarian cycle in compared to healthy controls(5).

Dr. Wetterberg L. said, " Patients with migraine,...........exhibited a decreased amplitude of their diurnal rhythm of melatonin" and "The change in melatonin secretion in human is apparently controlled by a mechanism which is at least party influenced by environmental lighting conditions, drugs and different disease states"(6).

The combination of Sweet potato and Pineapple smoothie may hold a key in further studies in production of an effective natural ingredients for prevention and treatment of Menstrual Migraines without inducing adverse effects.

Women who are at higher risk of Menstrual Migraines due to family history, obesity,...should take at least one serving daily. Women with Menstrual Migraines should drink as much as they can depending to the digestive toleration.

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Reference
(1) Prevention and treatment of menstrual migraine by MacGregor EA1(PubMed)
(2) Vitamin supplementation as possible prophylactic treatment against migraine with aura and menstrual migraine. by Shaik MM1, Gan SH1.(PubMed)
(3) The effect of vitamin E on the treatment of menstrual migraine by Ziaei S1, Kazemnejad A, Sedighi A.(PubMed)
(4) Melatonin, 3 mg, is effective for migraine prevention by Peres MF1, Zukerman E, da Cunha Tanuri F, Moreira FR, Cipolla-Neto J.(PubMed)
(5) Urinary melatonin excretion throughout the ovarian cycle in menstrually related migraine by Murialdo G1, Fonzi S, Costelli P, Solinas GP, Parodi C, Marabini S, Fanciullacci M, Polleri A.(PubMed)
(6) Melatonin in humans physiological and clinical studies by Wetterberg L.(PubMed)

The Obesity's Weight Loss Recipes: Carrot raisin salad

Kyle J. Norton(Scholar, Master of Nutrients), all right reserved.
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

Recipe attributed to Company's Coming Salads by Jean Parè

A lunch box winner

Grated carrot 2 cups (500 ml)
Raison (see note) 1/2 cup (125 ml)
Salad dressing ( or mayonnaise) 1/3 cup (75 ml)
Vinegar 1tbsp. 15 ml
Put all ingredients into a bowl. Toss to coat. Serve 6.
Note: If raisins are too dry. Covered in equal amount of water to 2 minutes. Let stand until cool. Drain. Pat dry with paper towel.
Variation: Add 1/2 cup (125 ml) chopped celery.
Chinese Food Therapy
The Best Way to prevent, treat your disease, including Obesity
and restore your health naturally with Chinese diet

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

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Obesity and Obesity's complication - The association of Obesity on Infertility

Kyle J. Norton(Scholar, Master of Nutrients), all right reserved.
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

Obesity is a medical condition of excess body fat accumulated overtime, while overweight is a condition of excess body weight relatively to the height. According to the Body Mass Index(BMI), a BMI between 25 to 29.9 is considered over weight, while a BMI of over 30 is an indication of obesity. According to the statistic, 68% of American population are either overweight or obese.

You can calculate your BMI index BMI= weight (kg)/ height (m2)

Infertility is a condition of the female partner who can not get pregnant after 12 months of unprotected sexual intercourse.
How do calculate your BMI indexBMI= weight (kg)/ height (m2)

The associatiom obesity with Infertility
1. Hormonal effects
In a study of " Body mass index in relation to semen quality, sperm DNA integrity, and serum reproductive hormone levels among men attending an infertility clinic." by Chavarro JE, Toth TL, Wright DL, Meeker JD, Hauser R. (Source from Channing Laboratory, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts, USA. jchavarr@hsph.harvard.edu, Copyright 2010 American Society for Reproductive Medicine. Published by Elsevier Inc. All rights reserved.), posted in PubMed, using the Standard semen analysis, sperm DNA fragmentation, and serum levels of reproductive hormones, researchers found that despite major differences in reproductive hormone levels with increasing body weight, only extreme levels ofobesity may negatively influence male reproductive potential.

2. Sperm concentration and total sperm count
According to the study of " Is overweight a risk factor for reduced semen quality and altered serum sex hormone profile?" by Aggerholm AS, Thulstrup AM, Toft G, Ramlau-Hansen CH, Bonde JP. (Source from Department of Occupational Medicine, Aarhus University Hospital, Aarhus, Denmark. ansag@as.aaa.dk), posted in PubMed, researchers found that The T and inhibin B serum concentrations were 25%-32% lower in obese men in comparison with normal-weight men, whereas the E(2) concentration was 6% higher in obese men. Overweight men (BMI, 25.1-30.0 kg/m(2)) had a slightly lower adjusted sperm concentration and total sperm count than did men with a normal BMI (20.0-25.0 kg/m(2)), but no reduction in sperm count was observed among the obese men and suggested that that overweight and obese men have a markedly changed sex hormone profile in serum, whereas reduction of semen quality, if any, was marginal and below the detection limit of this large study.

3. Egg quality
In a stidu of " The impact of obesity on egg quality" by Purcell SH, Moley KH.(Source from Department of Obstetrics and Gynecology, Washington University in St. Louis, 660 South Euclid Ave., St. Louis, MO, 63110, USA), posted in PubMed, researchers found that Both oocyte maturation and metabolism are impaired due toobesity, negatively impacting further development. In addition to reproductive hormones, obesity induced elevations in insulin, glucose, or free fatty acids, and changes in adipokines appear to impact the developmental competence of the oocyte. The data indicate that any one of these hormones or metabolites can impair oocyte developmental competence in vivo, and the combination of all of these factors and their interactions are the subject of ongoing investigations

4. Ovarian structure and function
In a study of " The New Zealand obese mouse model of obesity insulin resistance and poor breeding performance: evaluation of ovarian structure and function" by Radavelli-Bagatini S, Blair AR, Proietto J, Spritzer PM, Andrikopoulos S. (Source from Department of Medicine (Austin Health/Northern Health), Heidelberg Repatriation Hospital, The University of Melbourne, Heidelberg Heights, Melbourne, Victoria 3081, Australia), researchers concluded that NZO mice (New Zealand obese mice) show a poor breeding performance due to decreased ovulation, increased number of primordial and atretic follicles, and ovarian size. Given that NZO mice are obese, hyperinsulinemic and insulin resistant, they are suitable for investigating pathophysiological mechanisms linking metabolic alterations with reproductive defects.

5. Ovarian dysfunction
According to the study of "Inflammatory pathways linking obesity and ovarian dysfunction" by
Robker RL, Wu LL, Yang X. (Source from School of Paediatrics and Reproductive Health, Robinson Institute, University of Adelaide, Adelaide, South Australia 5005, Australia. rebecca.robker@adelaide.edu.au, Copyright © 2011 Elsevier Ireland Ltd. All rights reserved), posted in PubMed, researchers found that Studies in mice support this and allow further dissection of the pathways by which diet-inducedobesity contributes to changes in mitochondria and the endoplasmic reticulum. These studies are in their infancy but cumulatively provide basic information about the cellular mechanisms that may lead to the impaired ovulation and reduced oocyte developmental potential that is observed in obese females.

6. Pregnancy-related complications
According to the study "Effect of body mass index on in vitro fertilization outcomes in women" by Sathya A, Balasubramanyam S, Gupta S, Verma T.(Source from Consultant Endocrinologist, Institute of Reproductive Medicine and Women's Health, Madras Medical Mission Hospital, Chennai, Tamil Nadu, India), posted in PobMed, researchers concluded in abstract that Increase in body mass index in women does not appear to have an adverse effect on IVF outcome. However, preconceptual counselling for obese women is a must as weight reduction helps in reducing pregnancy-related complications.

7. Etc.

Effect of Female obesity and Newborn
In a study of "[Obesity and female reproduction].[Article in French], by Sarfati J, Young J, Christin-Maitre S. (Source from Service d'Endocrinologie et des Maladies de la Reproduction, Centre Hospitalier Universitaire de Bicêtre - APHP, 78 rue du Général-Leclerc 94275 Le Kremlin-Bicêtre, France. sarfati_julie@yahoo.fr, Copyright Â© 2010 Elsevier Masson SAS. All rights reserved), posted in PobMed, researchers found that In this model, all weaned pups have been fed with a regular diet. At 13 weeks, pups delivered from obese mice were significantly larger, and these pups demonstrated early development of a metabolic-type syndrome. These findings suggest that maternal obesity has adverse effects as early as the oocyte and preimplantation embryo stages and that these effects may contribute to lasting morbidity in offspring, underscoring the importance of optimal maternal weight and nutrition before conception.

The importance of Obesity and Infertility treatment
1. According to the study of "Impact of obesity on female fertility and fertilitytreatment" by Zain MM, Norman RJ. (Source from University of Adelaide, Research Centre for Reproductive Health, School of Paediatrics & Reproductive Health, South Australia, Australia. murizah.mohdzain@adelaide.edu.au), posted in PubMed, researchers filed in abstract that treatment of obesity itself should be the initial aim in obese infertile women before embarking on ovulation-induction drugs or assisted reproductive techniques. While various strategies for weight reduction, including diet, exercise, pharmacological and surgical intervention exist, lifestyle modification continues to be of paramount importance.

2. In a study of "Improving reproductive performance in overweight/obese women with effective weight management" by Norman RJ, Noakes M, Wu R, Davies MJ, Moran L, Wang JX. (Source from Reproductive Medicine Unit, University of Adelaide, The Queen Elizabeth Hospital, Woodville Rd, Woodville, SA5011, Australia_, posted in PubMed, researchers found that weight loss can improve the fertility of obese women through the recovery of spontaneous ovulation, whereas others will have improved response to ovarian stimulation in infertility treatment. Therefore, it is proposed that following the initial assessment of infertility and body mass index or other measurement of obesity, various weight management interventions, including diet, exercise or pharmacotherapeutic approaches, should be considered for overweight and obese infertile women.

3. Reported from the study of "The obese patient with infertility: a practical approach to diagnosis and treatment" by Moran LJ, Norman RJ. (Source from Reproductive Medicine Unit, Department of Obstetrics and Gynaecology, University of Adelaide, The Queen Elizabeth Hospital, South Australia, Australia), posted in Pubmed, researchers found that weight loss should be promoted as an initial treatment option for obese women with infertility. However, the most effective method for achieving and maintaining weight loss is unclear. Gradual weight loss is best achieved through a sensible eating plan that can be maintained over long periods of time. The likelihood of maintaining weight loss is increased when diet is combined with regular exercise, cognitive behavior therapy, and a supportive group environment. Adoption of these principles in a primary healthcare setting can therefore aid in treatment of infertility related to obesity.

4. Etc.

Chinese Food Therapy
The Best Way to prevent, treat your disease, including Obesity
and restore your health naturally with Chinese diet

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Super foods Library, Eat Yourself Healthy With The Best of the Best Nature Has to Offer