Kyle J. Norton(Scholar and Master of Nutrients, all right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.
Horsetail(Equisetum arvense)
Horsetail is a herbaceous perennial plant, of genus Equisetum, belonging toEquisetaceae, native to the arctic and temperate regions of the northern hemisphere. The herb has been used in traditional medicine to treat stop bleeding, heal ulcers and wounds, and treat tuberculosis, edema, kidney and bladder stones, urinary tract infections, incontinence, etc.
Health Benefits
1. Antioxidative and antiproliferative activities
In the investigation of the antioxidative and antiproliferative activity of differenthorsetail (Equisetum arvense L.) extracts found that ethyl acetate extract exhibited the most prominent antiproliferative effect, without inducing any cell growth stimulation on human tumor cell lines. The results obtained suggest that thehorsetail extracts could be used as an easily accessible source of natural antioxidants and as potential phytochemicals, according to "Antioxidative and antiproliferative activities of different horsetail (Equisetum arvense L.) extracts" by Cetojević-Simin DD, Canadanović-Brunet JM, Bogdanović GM, Djilas SM, Cetković GS, Tumbas VT, Stojiljković BT.(1)
2. Antioxidants
In the evaluation of antioxidant activity and phenolic composition of three different extracts (EtOAc, n-BuOH and H(2)O) of field horsetail (Equisetum arvense L.) found that the highest RSC regarding both DPPH and NO radicals is expressed by EtOAc extract (EC(50)=2.37 microg/mL and EC(50)=90.07 microg/mL, respectively), and the lowest by H(2)O extract (EC(50)=37.2 microg/mL and EC(50)>333.33 microg/mL, respectively). n-BuOH extract showed the highest total reducing power (AEAC=13.40 microg/mL), according to "Phenolic compounds in field horsetail (Equisetum arvense L.) as natural antioxidants" by Mimica-Dukic N, Simin N, Cvejic J, Jovin E, Orcic D, Bozin B.(2)
3. Anti fungal effect
In the assessment of The effectiveness of grape field antifungals (Switch, Flint Max and Equisetum arvense extract) found that the greatest reduction and E. arvense (0.02 g mL(-1) extract) the least. Higher temperatures affected OTA production by the isolates in different ways. In general, Switch and Flint Max reduced OTA production, while E. arvense stimulated it, according to "Ochratoxigenic moulds and effectiveness of grape field antifungals in a climatic change scenario" by García-Cela E, Ramos AJ, Sanchis V, Marin S.(3)
4. Anxiolytic effects
In the demonstration of the petroleum ether (PE), chloroform (CH), ethanol (ETH) and water extracts of E. arvense stems and theirs anti-anxiety effects found that the ethanolic extract of E. arvense seems to possess anxiolytic effect with lower sedative activity than that of diazepam. The results could be attributed to the flavonoid content of the ethanolic extract, according to "Anxiolytic effects ofEquisetum arvense Linn. extracts in mice" by Singh N, Kaur S, Bedi PM, Kaur D.(4)
5. Cytostatic activity
In the comparison of peptide extracts of medicinal plants and their Cytostatic activity found that the cytostatic effect was produced by peptide extracts of Camelia sinesis Kuntze, Inonotus obliquus, and a mixture Inula helenium L., Chelidonium majus L., Equisetum arvense L., and Inonotus obliquus, accoridng to "Cytostatic activity of peptide extracts of medicinal plants on transformed A549, H1299, and HeLa Cells" by Tepkeeva II, Aushev VN, Zborovskaya IB, Demushkin VP.(5)
6. Antitumor activity
In the investigation of a peptide extract PE-PM obtained from a mixture of Chelidonium majus L., Inula helenium L., Equisetum arvense L. and Inonotus obliquus and theirs antitumor activities, found that distinct antitumor activity of two local injections of the peptide extract PE-PM was detected by tumor growth inhibition and survival improvement of 33% of recipients bearing intraperitoneal form of ASF-LL, according to "[Antitumor activity of the plant remedy peptide extract PE-PM in a new mouse T-lymphoma/eukemia model].[Article in Russian]" by Chaadaeva AV, Tenkeeva II, Moiseeva EV, Svirshchevskaia EV, Demushkin VP.(6)
7. Breast cancer
In the comparison of peptide extracts from plants on slowly growing mammary adenocarcinoma in CBRB-Rb(8.17)1Iem mice used as a model of breast cancer in humans, found that Peptides from Hypericum perforatum and a mixture of Chelidonium majus L., Inula helenium L., Equisetum arvense L., and Inonotus obliquus exhibited maximum activity, according to "Evaluation of antitumor activity of peptide extracts from medicinal plants on the model of transplanted breast cancer in CBRB-Rb(8.17)1Iem mice" by Tepkeeva II, Moiseeva EV, Chaadaeva AV, Zhavoronkova EV, Kessler YV, Semushina SG, Demushkin VP.(7)
8. Anti diabetes
in the assessment of the methanolic extract of Equisetum arvense was analysed for its antidiabetic activity in streptozotocin-induced diabetic rats found that methanolic extract of Equisetum arvense produced a significant antidiabetic activity at doses 50 and 50 mg kg(-1)/b.wt. Concurrent histological studies of the pancreas of these animals showed comparable regeneration by methanolic extract which were earlier, necrosed by streptozotocin, accoridng to "The effect ofEquisetum arvense L. (Equisetaceae) in histological changes of pancreatic beta-cells in streptozotocin-induced diabetic in rats" by Soleimani S, Azarbaizani FF, Nejati V.(8)
9. Genotoxicity, antimicrobial activity, antioxidant effects
In the identification of the hydro-alcoholic extracts of five Equisetum species, E. arvense L., E. sylvaticum L., E. fluviatile L., E. palustre L. and E. telmateia Ehrh., growing-wild in Serbia and their genotoxicity, antimicrobial activity, antioxidant effects found that All tested extracts at 62.5 microg/ml showed higher incidence of micronucleus formation than in the control sample. The obtained data allowed mutual comparison of examined species and their assessment as possible sources of antioxidants, antimicrobials and/or genotoxic substances, according to "Antioxidant, antimicrobial and genotoxicity screening of hydro-alcoholic extracts of five serbian Equisetum species" by Milovanović V, Radulović N, Todorović Z, Stanković M, Stojanović G.(9)
10. Benign prostatic hyperplasia (BPH)
In the observation of four extracts from Chimaphila umbellata, Populus tremula, Pulsatilla pratensis and Equisetum arvense (coded as EVI-1, EVI-2, EVI-3 and EVI-4, respectively) and germ oil from Triticum aestivum (coded as EVI-5) and theirs effects on reactive oxygen species (ROS), superoxide anion (O2-) and hydroxyl radical (OH*) found that the suppression of ROS by EVI-1, EVI-2 and EVI-4 may partly contribute to the anti-inflammatory action of eviprostat, and this action may be implicated in its therapeutic effect on BPH, according to "Relevance of anti-reactive oxygen species activity to anti-inflammatory activity of components of eviprostat, a phytotherapeutic agent for benign prostatic hyperplasia" by Oka M, Tachibana M, Noda K, Inoue N, Tanaka M, Kuwabara K.(10)
11. Sedative and anticonvulsant effects
In the evaluation of the hydroalcoholic extract of Equisetum arvense (HAE) tested at the doses of 200 and 400 mg/kg and its Sedative and anticonvulsant effects found that HAE presented anticonvulsant and sedative effects. Phytochemical analysis detected the presence of tannins, saponins, sterols and flavonoids, according to "Sedative and anticonvulsant effects of hydroalcoholic extract ofEquisetum arvense" by Dos Santos JG Jr, Blanco MM, Do Monte FH, Russi M, Lanziotti VM, Leal LK, Cunha GM.(11)
12. Cognitive effects
In the study of the hydroalcoholic extract of stems from Equisetum arvense (HAE) reverses the cognitive impairment in aged rats found that HAE diminished the thiobarbituric acid reactive substances as well as nitrite formation, but did not alter catalase activity. Thus, the cognitive enhancement effects of the HAE may be attributed, at least in part, to it antioxidant action, according to "Cognitive enhancement in aged rats after chronic administration of Equisetum arvense L. with demonstrated antioxidant properties in vitro" by Guilherme dos Santos J Jr, Hoffmann Martins do Monte F, Marcela Blanco M, Maria do Nascimento Bispo Lanziotti V, Damasseno Maia F, Kalyne de Almeida Leal L.(12)
13. Etc.
Side effects
1. Horsetail may interact with other herbs and certain medication
2. Prolonged use of the herb may cause depletion of vitamin B1 (thiamin) and potassium
3. Do not take horsetail if you have heart or kidney disease, diabetes, etc.
4. Do not take the herb in children, or if you are pregnant or breast feeding without permission of the related field specialist.
5. Etc.
Chinese Food Therapy
The Best Way to prevent, treat your disease, including Obesity
and restore your health naturally with Chinese diet
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Super foods Library, Eat Yourself Healthy With The Best of the Best Nature Has to Offer
Sources
(1) http://www.ncbi.nlm.nih.gov/pubmed/20170379
(2) http://www.ncbi.nlm.nih.gov/pubmed/18719517
(3) http://www.ncbi.nlm.nih.gov/pubmed/22131267
(4) http://www.ncbi.nlm.nih.gov/pubmed/21615059
(5) http://www.ncbi.nlm.nih.gov/pubmed/19526129
(6) http://www.ncbi.nlm.nih.gov/pubmed/19351037
(7) http://www.ncbi.nlm.nih.gov/pubmed/19110595
(8) http://www.ncbi.nlm.nih.gov/pubmed/19086577
(9) http://www.ncbi.nlm.nih.gov/pubmed/17676400
(10) http://www.ncbi.nlm.nih.gov/pubmed/17583488
(11) http://www.ncbi.nlm.nih.gov/pubmed/15972249
(12) http://www.ncbi.nlm.nih.gov/pubmed/15972233
Tuesday, June 21, 2016
Phytochemicals in Foods - The Effects of Coumarin
Kyle J. Norton(Scholar and Master of Nutrients, all right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.
Coumarin
Coumarin is a phytochemical in the class of Lignans (phytoestrogens), belonging to the flavonoid in Flavonoids (polyphenols), found abundantly in citrus fruits, maize, etc.
Health Benefits
1. Anti tumors
In the investigation of the amphiphilic 7-carboxymethoxy coumarin monoend-functionalized methoxy poly(ethylene glycol) (mPEG-Lys-DCOU) chains and its self-assembled micelles, anti-tumor drug, found that both in vitro and in vivo studies demonstrated that the inhibition efficacy of drug-loaded micelles were comparable to that of doxorubicin hydrochloride. mPEG-Lys-DCOU micelles are promising carriers for anti-tumor drug delivery, according to "A novel micelle ofcoumarin derivative monoend-functionalized PEG for anti-tumor drug delivery: in vitro and in vivo study" by Lai Y, Long Y, Lei Y, Deng X, He B, Sheng M, Li M, Gu Z.(1)
2. Gastric cancer
In the investigation of an anti-mitotic potential of the novel synthetic coumarin-based compound, 7-diethylamino-3(2'-benzoxazolyl)-coumarin, in 5-fluorouracil-resistant human gastric cancer cell line SNU-620-5FU and its parental cell SNU-620, found that this compound enhances caspase-dependent apoptotic cell death via decreased expression of anti-apoptotic genes. Taken together, our data strongly support anti-mitotic potential of 7-diethylamino-3(2'-benzoxazolyl)-coumarin against drug-resistant cancer cells which will prompt us to further develop as a novel microtubule inhibitor for drug-resistant cancer chemotherapy, according to "Anti-mitotic potential of 7-diethylamino-3(2'-benzoxazolyl)-coumarin in 5-fluorouracil-resistant human gastric cancer cell line SNU620/5-FU' by Kim NH, Kim SN, Oh JS, Lee S, Kim YK.(2)
3. Anti cancers
In the identification of a novel coumarin analogue with the highest anticancer activity and further to its anticancer mechanisms, found that The compound had a broad spectrum of anticancer activity against 9 cancer cell lines derived from colon cancer, breast cancer, liver cancer, cervical cancer, leukemia, epidermoidcancer with IC(50) value of 75 nmol/L-1.57 μmol/L but with low cytotocitity against WI-38 human lung fibroblasts (IC(50) value of 12.128 μmol/L). The compound (0.04-10 μmol/L) induced G(2)-M phase arrest in HeLa cells in a dose-dependent manner, which was reversible after the compound was removed. The compound (10-300 μmol/L) induced the depolymerization of purified porcine tubulin in vitro. Finally, the compound (0.04-2.5 μmol/L) induced apoptosis of HeLa cells in dose- and time-dependent manners.Conclusion:6-Chloro-4-(methoxyphenyl) coumarin is a novel microtubule-targeting agent that induces G(2)-M arrest and apoptosis in HeLa cells, according to "Novel microtubule-targeted agent 6-chloro-4-(methoxyphenyl) coumarin induces G(2)-M arrest and apoptosis in HeLa cells" by Ma YM, Zhou YB, Xie CM, Chen DM, Li J.(3)
4. Antioxidant and anti-inflammatory activities
In the evaluation of the antioxidant and antiinflammatory activities of methanolic extract of whole plants of Angelica decursiva, and its solvent soluble fractions via in vitro, found that Among the tested fractions, the ethyl acetate fraction was found as the most active antioxidant fraction together with significant anti-inflammatory effect. From the active ethyl acetate fraction, four coumarinderivatives consisting of nodakenin, nodakenetin, umbelliferone, and umbelliferone-6-carboxylic acid, along with a phenolic compound, vanillic acid, were isolated. Among them, umbelliferone 6-carboxylic acid and vanillic acid were isolated for the first time from this plant. In all antioxidant assays, vanillic acid showed the highest antioxidant potential followed by umbelliferone 6-carboxylic acid among the isolated compounds. In the anti-inflammatory assay,umbelliferone 6-carboxylic acid exhibited the highest inhibitory activity against lipopolysaccharide-induced NO production in RAW 264.7 cells with an IC(50) value of 72.98 μg/mL, according to "In vitro antioxidant and anti-inflammatory activities of Angelica decursiva" by Zhao D, Islam MN, Ahn BR, Jung HA, Kim BW, Choi JS.(4)
5. Antimicrobial activity
In the investigation of the antibacterial and antifungal activities of Ulopterol, acoumarin isolated as another major active antimicrobial principle, found that the ethyl acetate extract which was found to possess highest antimicrobial activity was subjected to activity guided fractionation by column chromatography over silica gel. This resulted in the isolation of the coumarin, Ulopetrol, an active principle besides Flindersine which was reported by us earlier, according to "Antimicrobial activity of Ulopterol isolated from Toddalia asiatica (L.) Lam.: A traditional medicinal plant" by Karunai Raj M, Balachandran C, Duraipandiyan V, Agastian P, Ignacimuthu S.(5)
6. Alzheimer's disease
In a review of the differently synthesized coumarin derivatives as AChE inhibitors for management of AD indicated that the coumarin template for synthesizing novel AChE inhibitors with additional pharmacological activities including decrease in beta-amyloid (Aβ) deposition and beta-secretase inhibition are also important for AD management, according to "A review on coumarins as acetylcholinesterase inhibitors for Alzheimer's disease" by Anand P, Singh B, Singh N.(6)
7. Neuroprotective effects
In the investigation of the potential protective effects of osthole, a coumarincompound isolated from the plant-derived herb Cnidium monnieri in adult rats in the setting of traumatic brain injury (TBI), found that pretreatment with osthole (40 mg/kg) significantly increased the activity of SOD, the level of GSH, and the ratio of Bcl-2/Bax, and also reduced the level of MDA, the expression of active caspase-3, and the number of apoptotic cells at 24h after TBI. In summary, these results suggested that osthole had a neuroprotective effect against TBI, and the protection may be associated with its antioxidative and antiapoptotic functions, according to "Neuroprotective effects of osthole pretreatment against traumatic brain injury in rats" by He Y, Qu S, Wang J, He X, Lin W, Zhen H, Zhang X.(7)
8. Anticonvulsants
In the investigation of a series of coumarin incorporated 1,2,4- triazole compounds (1-14) for their possible anticonvulsant and neurotoxic properties, log P values, pharmacophoric mapping and three dimensional structure analysis, found that Compound (6) with para-fluoro substitution showed significant anticonvulsant activity, according to "Coumarin incorporated triazoles: a new class of anticonvulsants" by Bhat MA, Al-Omar MA.(8)
9. Hepatitis B virus
In the investigation of three new lignans, erythro-strebluslignanol (1), threo-7'-methoxyl strebluslignanol (2) and erythro-7'-methoxyl strebluslignanol (3), together with twelve known compounds were isolated from the n-butanol and chloroform fractions of the heartwood of Streblus asper, found that 6-hydroxyl-7-methoxyl-coumarin (5) and ursolic acid (10) showed anti-HBV activities, with IC(50) values of 29.60μM and 89.91μM for HBsAg at no cytotoxicity, and IC(50) values of 46.41μM and 97.61μM for HBeAg at no cytotoxicity, respectively, according to "Lignans from the heartwood of Streblus asper and their inhibiting activities to Hepatitis B virus" by Li LQ, Li J, Huang Y, Wu Q, Deng SP, Su XJ, Yang RY, Huang JG, Chen ZZ, Li S.(9)
(10). Etc.
Chinese Food Therapy
The Best Way to prevent, treat your disease, including Obesity
and restore your health naturally with Chinese diet
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Super foods Library, Eat Yourself Healthy With The Best of the Best Nature Has to Offertml
Back to Kyle J. Norton Home page http://kylejnorton.blogspot.ca
Sources
(1) http://www.ncbi.nlm.nih.gov/pubmed/22118403
(2) http://www.ncbi.nlm.nih.gov/pubmed/22301191
(3) http://www.ncbi.nlm.nih.gov/pubmed/22266726
(4) http://www.ncbi.nlm.nih.gov/pubmed/22297757
(5) http://www.ncbi.nlm.nih.gov/pubmed/22265751
(6) http://www.ncbi.nlm.nih.gov/pubmed/22257528
(7) http://www.ncbi.nlm.nih.gov/pubmed/22153917
(8) http://www.ncbi.nlm.nih.gov/pubmed/22125954
(9) http://www.ncbi.nlm.nih.gov/pubmed/22119765
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.
Coumarin
Coumarin is a phytochemical in the class of Lignans (phytoestrogens), belonging to the flavonoid in Flavonoids (polyphenols), found abundantly in citrus fruits, maize, etc.
Health Benefits
1. Anti tumors
In the investigation of the amphiphilic 7-carboxymethoxy coumarin monoend-functionalized methoxy poly(ethylene glycol) (mPEG-Lys-DCOU) chains and its self-assembled micelles, anti-tumor drug, found that both in vitro and in vivo studies demonstrated that the inhibition efficacy of drug-loaded micelles were comparable to that of doxorubicin hydrochloride. mPEG-Lys-DCOU micelles are promising carriers for anti-tumor drug delivery, according to "A novel micelle ofcoumarin derivative monoend-functionalized PEG for anti-tumor drug delivery: in vitro and in vivo study" by Lai Y, Long Y, Lei Y, Deng X, He B, Sheng M, Li M, Gu Z.(1)
2. Gastric cancer
In the investigation of an anti-mitotic potential of the novel synthetic coumarin-based compound, 7-diethylamino-3(2'-benzoxazolyl)-coumarin, in 5-fluorouracil-resistant human gastric cancer cell line SNU-620-5FU and its parental cell SNU-620, found that this compound enhances caspase-dependent apoptotic cell death via decreased expression of anti-apoptotic genes. Taken together, our data strongly support anti-mitotic potential of 7-diethylamino-3(2'-benzoxazolyl)-coumarin against drug-resistant cancer cells which will prompt us to further develop as a novel microtubule inhibitor for drug-resistant cancer chemotherapy, according to "Anti-mitotic potential of 7-diethylamino-3(2'-benzoxazolyl)-coumarin in 5-fluorouracil-resistant human gastric cancer cell line SNU620/5-FU' by Kim NH, Kim SN, Oh JS, Lee S, Kim YK.(2)
3. Anti cancers
In the identification of a novel coumarin analogue with the highest anticancer activity and further to its anticancer mechanisms, found that The compound had a broad spectrum of anticancer activity against 9 cancer cell lines derived from colon cancer, breast cancer, liver cancer, cervical cancer, leukemia, epidermoidcancer with IC(50) value of 75 nmol/L-1.57 μmol/L but with low cytotocitity against WI-38 human lung fibroblasts (IC(50) value of 12.128 μmol/L). The compound (0.04-10 μmol/L) induced G(2)-M phase arrest in HeLa cells in a dose-dependent manner, which was reversible after the compound was removed. The compound (10-300 μmol/L) induced the depolymerization of purified porcine tubulin in vitro. Finally, the compound (0.04-2.5 μmol/L) induced apoptosis of HeLa cells in dose- and time-dependent manners.Conclusion:6-Chloro-4-(methoxyphenyl) coumarin is a novel microtubule-targeting agent that induces G(2)-M arrest and apoptosis in HeLa cells, according to "Novel microtubule-targeted agent 6-chloro-4-(methoxyphenyl) coumarin induces G(2)-M arrest and apoptosis in HeLa cells" by Ma YM, Zhou YB, Xie CM, Chen DM, Li J.(3)
4. Antioxidant and anti-inflammatory activities
In the evaluation of the antioxidant and antiinflammatory activities of methanolic extract of whole plants of Angelica decursiva, and its solvent soluble fractions via in vitro, found that Among the tested fractions, the ethyl acetate fraction was found as the most active antioxidant fraction together with significant anti-inflammatory effect. From the active ethyl acetate fraction, four coumarinderivatives consisting of nodakenin, nodakenetin, umbelliferone, and umbelliferone-6-carboxylic acid, along with a phenolic compound, vanillic acid, were isolated. Among them, umbelliferone 6-carboxylic acid and vanillic acid were isolated for the first time from this plant. In all antioxidant assays, vanillic acid showed the highest antioxidant potential followed by umbelliferone 6-carboxylic acid among the isolated compounds. In the anti-inflammatory assay,umbelliferone 6-carboxylic acid exhibited the highest inhibitory activity against lipopolysaccharide-induced NO production in RAW 264.7 cells with an IC(50) value of 72.98 μg/mL, according to "In vitro antioxidant and anti-inflammatory activities of Angelica decursiva" by Zhao D, Islam MN, Ahn BR, Jung HA, Kim BW, Choi JS.(4)
5. Antimicrobial activity
In the investigation of the antibacterial and antifungal activities of Ulopterol, acoumarin isolated as another major active antimicrobial principle, found that the ethyl acetate extract which was found to possess highest antimicrobial activity was subjected to activity guided fractionation by column chromatography over silica gel. This resulted in the isolation of the coumarin, Ulopetrol, an active principle besides Flindersine which was reported by us earlier, according to "Antimicrobial activity of Ulopterol isolated from Toddalia asiatica (L.) Lam.: A traditional medicinal plant" by Karunai Raj M, Balachandran C, Duraipandiyan V, Agastian P, Ignacimuthu S.(5)
6. Alzheimer's disease
In a review of the differently synthesized coumarin derivatives as AChE inhibitors for management of AD indicated that the coumarin template for synthesizing novel AChE inhibitors with additional pharmacological activities including decrease in beta-amyloid (Aβ) deposition and beta-secretase inhibition are also important for AD management, according to "A review on coumarins as acetylcholinesterase inhibitors for Alzheimer's disease" by Anand P, Singh B, Singh N.(6)
7. Neuroprotective effects
In the investigation of the potential protective effects of osthole, a coumarincompound isolated from the plant-derived herb Cnidium monnieri in adult rats in the setting of traumatic brain injury (TBI), found that pretreatment with osthole (40 mg/kg) significantly increased the activity of SOD, the level of GSH, and the ratio of Bcl-2/Bax, and also reduced the level of MDA, the expression of active caspase-3, and the number of apoptotic cells at 24h after TBI. In summary, these results suggested that osthole had a neuroprotective effect against TBI, and the protection may be associated with its antioxidative and antiapoptotic functions, according to "Neuroprotective effects of osthole pretreatment against traumatic brain injury in rats" by He Y, Qu S, Wang J, He X, Lin W, Zhen H, Zhang X.(7)
8. Anticonvulsants
In the investigation of a series of coumarin incorporated 1,2,4- triazole compounds (1-14) for their possible anticonvulsant and neurotoxic properties, log P values, pharmacophoric mapping and three dimensional structure analysis, found that Compound (6) with para-fluoro substitution showed significant anticonvulsant activity, according to "Coumarin incorporated triazoles: a new class of anticonvulsants" by Bhat MA, Al-Omar MA.(8)
9. Hepatitis B virus
In the investigation of three new lignans, erythro-strebluslignanol (1), threo-7'-methoxyl strebluslignanol (2) and erythro-7'-methoxyl strebluslignanol (3), together with twelve known compounds were isolated from the n-butanol and chloroform fractions of the heartwood of Streblus asper, found that 6-hydroxyl-7-methoxyl-coumarin (5) and ursolic acid (10) showed anti-HBV activities, with IC(50) values of 29.60μM and 89.91μM for HBsAg at no cytotoxicity, and IC(50) values of 46.41μM and 97.61μM for HBeAg at no cytotoxicity, respectively, according to "Lignans from the heartwood of Streblus asper and their inhibiting activities to Hepatitis B virus" by Li LQ, Li J, Huang Y, Wu Q, Deng SP, Su XJ, Yang RY, Huang JG, Chen ZZ, Li S.(9)
(10). Etc.
Chinese Food Therapy
The Best Way to prevent, treat your disease, including Obesity
and restore your health naturally with Chinese diet
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Super foods Library, Eat Yourself Healthy With The Best of the Best Nature Has to Offertml
Back to Kyle J. Norton Home page http://kylejnorton.blogspot.ca
Sources
(1) http://www.ncbi.nlm.nih.gov/pubmed/22118403
(2) http://www.ncbi.nlm.nih.gov/pubmed/22301191
(3) http://www.ncbi.nlm.nih.gov/pubmed/22266726
(4) http://www.ncbi.nlm.nih.gov/pubmed/22297757
(5) http://www.ncbi.nlm.nih.gov/pubmed/22265751
(6) http://www.ncbi.nlm.nih.gov/pubmed/22257528
(7) http://www.ncbi.nlm.nih.gov/pubmed/22153917
(8) http://www.ncbi.nlm.nih.gov/pubmed/22125954
(9) http://www.ncbi.nlm.nih.gov/pubmed/22119765
Most Common Diseases of Men of 50Plus - Prostate Health - Cruciferous vegetables and Prostate cancer
Kyle J. Norton(Scholar and Master of Nutrients, all right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.
Cruciferous vegetables are the group of vegetables belonging to the family Brassicaceae, including cauliflower, cabbage, cress, bok choy, broccoli etc.
Broccoli is a mustard/cabbage plant, belong to the family Brassicaceae. It has large flower heads, usually green in color and the mass of flower heads is surrounded by leaves and evolved from a wild cabbage plant on the continent of Europe.
Prostate cancer is defined as a condition in which the cells of prostate has become cancerous, causing abnormal cell growth which spread to the distant parts of the body. Most prostate cancers are slow growing and enlarged prostate and prostate cancer may be detected during the Physical (rectum) exams.
Nutrients and chemical constituents
1. Carbohydrates
2. Sugars
3. Dietary fiber
4. Omega 3 fatty acid
5. Protein
6. Beta-carotene
7. Lutein and
8. Zeaxanthin
9. Thiamine (Vitamin B1)
10. Riboflavin (Vitamin B2)
11. Niacin (Vitamin B3)
12. Pantothenic acid (B5)
13. Vitamin B6
14. Folate (Vit. B9)
15. Vitamin C
16. Calcium
17. Tryptophan
18. Iron
19. Magnesium
20. Phosphorus
21.Potassium
22. Zinc
23. Etc.
Its chemical constutuents include glucosinolates, dithiolthiones, indoles , glucoraphanin, s-methyl cysteine sulfoxide, isothiocyanates, indole-3-carbinol, etc..
The benefits
Epidemiologically, chemical constituents of cruciferous vegetables, such as broccoli has shown to decrease incidence of prostate cancer. The depletion of gene of GSTM1 genotype of Glutathione S-transferase (GST) enzymes may be associated with an increased risk of cancer as these depletion reduced the function of GST in detoxifying certain potentially carcinogenic compounds. Study of broccoli involved the changes in global gene expression patterns in the humanprostate gland before, during and after a 12 month broccoli-rich diet, showed broccoli enhances the detoxified function of GSTM1 genotype resulting in complex changes to signalling pathways associated with inflammation and carcinogenesis in the prostate, through the interaction from the breakdown of glucosinolates—sulfur-containing compounds found in cruciferous vegetables with a signal sequence in the plasma. In other study, the effects of potent sulforaphane of isothiocyanates (ITCs) in broccoli, consistently found to be associated with reduced risk of prostate cancer, especially among men with GSTM1-present alleles, and may be used as chemopreventive agents against prostate cancer, with two or more servings per month.
Other study insisted that Selenium-enriched broccoli sprouts were superior to normal broccoli sprouts in inhibiting cell proliferation, decreasing prostate-specific antigen secretion, and inducing apoptosis of prostate cancer cells.
The Side effects
1. People who has over production of IgM immunoglobulins which makes blood thicken should talk to their doctor before taking high amount of broccoli.
2. Allergic reaction??
3. Etc.
Chinese Food Therapy
The Best Way to prevent, treat your disease, including Erectile Dysfunction
and restore your health naturally with Chinese diet
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Super foods Library, Eat Yourself Healthy With The Best of the Best Nature Has to Offer
Reference
(1) Broccoli consumption interacts with GSTM1 to perturb oncogenic signalling pathways in the prostate by Traka M, Gasper AV, Melchini A, Bacon JR, Needs PW, Frost V, Chantry A, Jones AM, Ortori CA, Barrett DA, Ball RY, Mills RD, Mithen RF.(PubMed)
(2) GSTT1 and GSTM1 null genotypes and the risk of gastric cancer: a case-control study in a Chinese population by Setiawan VW, Zhang ZF, Yu GP, Li YL, Lu ML, Tsai CJ, Cordova D, Wang MR, Guo CH, Yu SZ, Kurtz RC.(PubMed)
(3) Cruciferous vegetables, genetic polymorphisms in glutathione S-transferases M1 and T1, and prostate cancer risk by Joseph MA, Moysich KB, Freudenheim JL, Shields PG, Bowman ED, Zhang Y, Marshall JR, Ambrosone CB.(PubMed)
(4) Selenium enrichment of broccoli sprout extract increases chemosensitivity and apoptosis of LNCaP prostate cancer cells by Abdulah R, Faried A, Kobayashi K, Yamazaki C, Suradji EW, Ito K, Suzuki K, Murakami M, Kuwano H, Koyama H.(PubMed)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.
Cruciferous vegetables are the group of vegetables belonging to the family Brassicaceae, including cauliflower, cabbage, cress, bok choy, broccoli etc.
Broccoli is a mustard/cabbage plant, belong to the family Brassicaceae. It has large flower heads, usually green in color and the mass of flower heads is surrounded by leaves and evolved from a wild cabbage plant on the continent of Europe.
Prostate cancer is defined as a condition in which the cells of prostate has become cancerous, causing abnormal cell growth which spread to the distant parts of the body. Most prostate cancers are slow growing and enlarged prostate and prostate cancer may be detected during the Physical (rectum) exams.
Nutrients and chemical constituents
1. Carbohydrates
2. Sugars
3. Dietary fiber
4. Omega 3 fatty acid
5. Protein
6. Beta-carotene
7. Lutein and
8. Zeaxanthin
9. Thiamine (Vitamin B1)
10. Riboflavin (Vitamin B2)
11. Niacin (Vitamin B3)
12. Pantothenic acid (B5)
13. Vitamin B6
14. Folate (Vit. B9)
15. Vitamin C
16. Calcium
17. Tryptophan
18. Iron
19. Magnesium
20. Phosphorus
21.Potassium
22. Zinc
23. Etc.
Its chemical constutuents include glucosinolates, dithiolthiones, indoles , glucoraphanin, s-methyl cysteine sulfoxide, isothiocyanates, indole-3-carbinol, etc..
The benefits
Epidemiologically, chemical constituents of cruciferous vegetables, such as broccoli has shown to decrease incidence of prostate cancer. The depletion of gene of GSTM1 genotype of Glutathione S-transferase (GST) enzymes may be associated with an increased risk of cancer as these depletion reduced the function of GST in detoxifying certain potentially carcinogenic compounds. Study of broccoli involved the changes in global gene expression patterns in the humanprostate gland before, during and after a 12 month broccoli-rich diet, showed broccoli enhances the detoxified function of GSTM1 genotype resulting in complex changes to signalling pathways associated with inflammation and carcinogenesis in the prostate, through the interaction from the breakdown of glucosinolates—sulfur-containing compounds found in cruciferous vegetables with a signal sequence in the plasma. In other study, the effects of potent sulforaphane of isothiocyanates (ITCs) in broccoli, consistently found to be associated with reduced risk of prostate cancer, especially among men with GSTM1-present alleles, and may be used as chemopreventive agents against prostate cancer, with two or more servings per month.
Other study insisted that Selenium-enriched broccoli sprouts were superior to normal broccoli sprouts in inhibiting cell proliferation, decreasing prostate-specific antigen secretion, and inducing apoptosis of prostate cancer cells.
The Side effects
1. People who has over production of IgM immunoglobulins which makes blood thicken should talk to their doctor before taking high amount of broccoli.
2. Allergic reaction??
3. Etc.
Chinese Food Therapy
The Best Way to prevent, treat your disease, including Erectile Dysfunction
and restore your health naturally with Chinese diet
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Super foods Library, Eat Yourself Healthy With The Best of the Best Nature Has to Offer
Reference
(1) Broccoli consumption interacts with GSTM1 to perturb oncogenic signalling pathways in the prostate by Traka M, Gasper AV, Melchini A, Bacon JR, Needs PW, Frost V, Chantry A, Jones AM, Ortori CA, Barrett DA, Ball RY, Mills RD, Mithen RF.(PubMed)
(2) GSTT1 and GSTM1 null genotypes and the risk of gastric cancer: a case-control study in a Chinese population by Setiawan VW, Zhang ZF, Yu GP, Li YL, Lu ML, Tsai CJ, Cordova D, Wang MR, Guo CH, Yu SZ, Kurtz RC.(PubMed)
(3) Cruciferous vegetables, genetic polymorphisms in glutathione S-transferases M1 and T1, and prostate cancer risk by Joseph MA, Moysich KB, Freudenheim JL, Shields PG, Bowman ED, Zhang Y, Marshall JR, Ambrosone CB.(PubMed)
(4) Selenium enrichment of broccoli sprout extract increases chemosensitivity and apoptosis of LNCaP prostate cancer cells by Abdulah R, Faried A, Kobayashi K, Yamazaki C, Suradji EW, Ito K, Suzuki K, Murakami M, Kuwano H, Koyama H.(PubMed)
The Obesity's Weight Loss Recipes: Julie's White Carrot salad
Kyle J. Norton(Scholar, Master of Nutrients), all right reserved.
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.
The Best Weight Loss and Healthy Recipe, Quoted from Raw food, volume 2, Healthy, delicious vegetarian cuisine made with living foods vt Lisa Montgonery, editor, hatherleigh
By Antanas Vainius
Prep. 10 minutes
2 tbsp. tarragon, crushed
1 lime juice
Bunch baby white carrots, sliced
2/3 cup medium diakon, grated
3 tbsp.olive oil
Full spectrum salt to taste
Soak tarragon in lime juice for 5 minutes. Toss diakon and carrots and pour tarragon mixture on carrots/ diakon and olive oil, salt, toss and serve.
Serve on de-seeded tomatoes wegdes.
Chinese Food Therapy
The Best Way to prevent, treat your disease, including Obesity
and restore your health naturally with Chinese diet
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Super foods Library, Eat Yourself Healthy With The Best of the Best Nature Has to Offer
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.
The Best Weight Loss and Healthy Recipe, Quoted from Raw food, volume 2, Healthy, delicious vegetarian cuisine made with living foods vt Lisa Montgonery, editor, hatherleigh
By Antanas Vainius
Prep. 10 minutes
2 tbsp. tarragon, crushed
1 lime juice
Bunch baby white carrots, sliced
2/3 cup medium diakon, grated
3 tbsp.olive oil
Full spectrum salt to taste
Soak tarragon in lime juice for 5 minutes. Toss diakon and carrots and pour tarragon mixture on carrots/ diakon and olive oil, salt, toss and serve.
Serve on de-seeded tomatoes wegdes.
Chinese Food Therapy
The Best Way to prevent, treat your disease, including Obesity
and restore your health naturally with Chinese diet
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Super foods Library, Eat Yourself Healthy With The Best of the Best Nature Has to Offer
The Obesity' Research and Studies of Intentional weight loss and dose reductions of anti-diabetic medications
Kyle J. Norton(Scholar and Master of Nutrients, all right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.
Obesity is a medical condition of excess body fat accumulated overtime, while overweight is a condition of excess body weight relatively to the height. According to the Body Mass Index(BMI), a BMI between 25 to 29.9 is considered over weight, while a BMI of over 30 is an indication of obesity. According to the statistic, 68% of American population are either overweight or obese.
You can calculate your BMI index BMI= weight (kg)/ height (m2)
The Studies of Intentional weight loss and dose reductions of anti-diabetic medications
In the investigation to study the mean starting BMI was 35 kg/m(2), mean age 53.4 years, and 58% were male. All 50 used at least one anti-diabetic medication (30 metformin, 39 sulfonylureas, 31 insulin, 21 sitagliptin) to manage blood sugar. Mean duration of follow-up was 30.2 months. Mean weight loss was 10.8 ± 4.1 kgs (11.1% of initial body weight ± 4.7%). 22/50 patients (44%) discontinued anti-diabetes medications (14 sulfonylureas [36%], 7 insulin [23%], 4 sitagliptin [19%]), found that the mean percentage weight loss achieved at the point of successful discontinuation of medication was 11.2% ± 3.5% (14% for sulphonylureas, 11% for insulin, and 7.1% for sitagliptin). Mean percentage weight loss of 5.6% ± 2.8% (5.1% for sulphonylureas, 4.3% for insulin, and 7.1% for sitagliptin) was required for initial dose reduction. For every 5% weight loss, predicted dose reductions were sulphonylureas, 39%; insulin, 42%; and any anti-diabetic medications, 49%. by Johns Hopkins Bloomberg School of Public Health
Chinese Food Therapy
The Best Way to prevent, treat your disease, including Obesity
and restore your health naturally with Chinese diet
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Super foods Library, Eat Yourself Healthy With The Best of the Best Nature Has to Offer
(1) "Intentional weight loss and dose reductions of anti-diabetic medications--a retrospective cohort study" by Kumar AA, Palamaner Subash Shantha G, Kahan S, Samson RJ, Boddu ND, Cheskin LJ.
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.
Obesity is a medical condition of excess body fat accumulated overtime, while overweight is a condition of excess body weight relatively to the height. According to the Body Mass Index(BMI), a BMI between 25 to 29.9 is considered over weight, while a BMI of over 30 is an indication of obesity. According to the statistic, 68% of American population are either overweight or obese.
You can calculate your BMI index BMI= weight (kg)/ height (m2)
The Studies of Intentional weight loss and dose reductions of anti-diabetic medications
In the investigation to study the mean starting BMI was 35 kg/m(2), mean age 53.4 years, and 58% were male. All 50 used at least one anti-diabetic medication (30 metformin, 39 sulfonylureas, 31 insulin, 21 sitagliptin) to manage blood sugar. Mean duration of follow-up was 30.2 months. Mean weight loss was 10.8 ± 4.1 kgs (11.1% of initial body weight ± 4.7%). 22/50 patients (44%) discontinued anti-diabetes medications (14 sulfonylureas [36%], 7 insulin [23%], 4 sitagliptin [19%]), found that the mean percentage weight loss achieved at the point of successful discontinuation of medication was 11.2% ± 3.5% (14% for sulphonylureas, 11% for insulin, and 7.1% for sitagliptin). Mean percentage weight loss of 5.6% ± 2.8% (5.1% for sulphonylureas, 4.3% for insulin, and 7.1% for sitagliptin) was required for initial dose reduction. For every 5% weight loss, predicted dose reductions were sulphonylureas, 39%; insulin, 42%; and any anti-diabetic medications, 49%. by Johns Hopkins Bloomberg School of Public Health
Chinese Food Therapy
The Best Way to prevent, treat your disease, including Obesity
and restore your health naturally with Chinese diet
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Super foods Library, Eat Yourself Healthy With The Best of the Best Nature Has to Offer
(1) "Intentional weight loss and dose reductions of anti-diabetic medications--a retrospective cohort study" by Kumar AA, Palamaner Subash Shantha G, Kahan S, Samson RJ, Boddu ND, Cheskin LJ.
The Holistic prevention, management and treatment of Polycystic Ovarian Syndrome:The Symptoms and Differentiations In TCM
Kyle J. Norton(Scholar, Master of Nutrients), all right reserved.
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.
Polycystic Ovarian Syndrome
Polycystic Ovarian Syndrome is defined as endocrinologic diseases among reproductive-age women caused by undeveloped follicles clumping on the ovaries that interferes with the function of the normal ovaries associated with a high risk for metabolic disorder(1) as resulting of enlarged ovaries(2), leading to hormone imbalance(excessive androgen and anti-müllerian hormone (AMH) )(1)(3)(4)(5), induced Hirsutism(6)(7), reproductive disorder(10(12)), risks of type 2 diabetes(9)(10)(11), metabolic syndrome(10)(12) and early cardiovascular disease(8)(13), acne(10)(14), endometrial cancer(18)(19),weight gain and obesity(15)(16)(17). The syndrome effects over 5% of women population or 1 in 20 women.
Unfortunately, according to studies, women with PCOs after the reproductive age, are associated to continuously increase risk of type II diabetes, with no increasingaltered glucose tolerance(20), CVD and hypertension(21).
In Traditional Chinese Medicine Perspective
While conventional medicine focus of using synthetic medication to induce ovulation and assisted artificial insemination for infertility couple, if the medicine fail, traditional Chinese medicine views polycystic ovarian syndrome in different approaches.
Polycystic ovary syndrome, according to traditional Chinese medicine is a medical condition characterized by accumulative of fluid over a prolonged period of time causes of dampness and phlegms(247a)(247b) build up on the ovaries due to the effects of vary differentiations, affecting not only the women’s menstrual cycle, but also ovulation and fertility(1247a)(247b).
Symptoms
According to statistic, most common symptoms of Chinese women with PCOs in traditional Chinese medicine include(1247)
1. Abdomen pain before menstrual onset
2. Obfuscation color
3. Cold lower abdomen
4. Insomnia
5. Fatigue
6. Eyes dark, face dark or ring lip dark, before and after menstruation
7. Chest tightness
8. Irritability
9. Depression
10. Lower abdomen pain during menstruation
11. Breast swelling
12. Etc.
Differentiation
Depending to differentiation of the diseases, PCOs according to TCM can be classified onto
A. General syndrome
1. Kidney deficiency syndrome(1246)
2. Stagnation of Qi and blood stasis(1246)
3. Dampness heat of liver(1246)(1248)
4. Stagnation of phlegm dampness syndrome(1246)
B. Single or combination syndrome
4. Kidney Yang deficiency and blood stasis(1247)
5. Kidney Yang deficiency (1247)(1248)
6. Kidney Yin deficiency and blood stasis(1147)
7. Kidney Yin deficiency and liver Qi stagnation syndrome(1247)
8. Kidney Yang deficiency and phlegm dampness stagnation(1247)
9. Kidney Yin deficiency(147)(1248)
10. Spleen-Yang deficiency (SYD)(1248)
(1246) [Clinical study of area of Jiangsu province of polycystic ovarian syndrome correlation distribution of traditional Chinese medicine syndrome type and improper diet]. [Article in Chinese] by Feng Y, Gao YP.(PubMed)
(1247) [Preliminary study on relationship of disease-syndrome-symptom of ovulatory disorder infertility based on factor analysis]. [Article in Chinese] by Li M, Ma K, Shan, J.(PubMed)
(1248) Spleen-yang-deficiency patients with polycystic ovary syndrome have higher levels of visfatin by Fu H, Qiu Y, Xia M, Wei F, He H, Yang L.(PubMed)
(1249)
Chinese Food Therapy
The Best Way to prevent, treat your disease, including Obesity
and restore your health naturally with Chinese diet
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Super foods Library, Eat Yourself Healthy With The Best of the Best Nature Has to Offer
References
(1) Adiposity and metabolic dysfunction in polycystic ovary syndrome by Sam S.(PubMed)
(2) A "kiss" before conception: triggering ovulation with kisspeptin-54 may improve IVF by Young SL.(PubMed)
(3.) Androgen hyperfunction and excessive heterosexual hair growth in women, with special attention to the polycystic ovarian syndrome by Lunde O1.(PubMed)
(4) Expression of anti-Müllerian hormone in letrozole rat model of polycystic ovary syndrome by Du DF1, Li XL, Fang F, Du MR.(PubMed)
(5) [Serum levels of anti-muller hormone in women with polycystic ovary syndromeand healthy women of reproductive age].[Article in Bulgarian] by Parahuleva N, Pehlivanov B, Orbecova M, Deneva T, Uchikova E.(PubMed)
(6) [Current opinions on the etiology and pathophysiology of hirsutism].[Article in Polish] by Krysiak R1, Kedzia A, Okopień B.(PubMed)
(7) The clinical evaluation of hirsutism by Somani N1, Harrison S, Bergfeld WF.(PubMed)
(8) Polycystic ovary syndrome and insulin: our understanding in the past, present and future by Mayer SB1, Evans WS, Nestler JE.(PubMed)
(9) Association of mean platelet volume with androgens and insulin resistance in nonobese patients with polycystic ovary syndrome by Dogan BA1, Arduc A2, Tuna MM1, Karakılıc E1, Dagdelen I1, Tutuncu Y1, Berker D1, Guler S1.(PubMed)
(10) Approach to the patient: contraception in women with polycystic ovary syndrome by Yildiz BO1.(PubMed)
(11) Polycystic ovarian syndrome (PCOS): a significant contributor to the overall burden of type 2 diabetes in women by Talbott EO1, Zborowski JV, Rager JR, Kip KE, Xu X, Orchard TJ.(PubMed)
(12) Prevalence of vitamin D deficiency in Slovak women with polycystic ovary syndrome and its relation to metabolic and reproductive abnormalities by Figurová J1, Dravecká I, Javorský M, Petríková J, Lazúrová I.(PubMed)
(13) Role of Insulin Sensitizers on Cardiovascular Risk Factors in Polycystic Ovarian Syndrome: A Meta-Analysis by Thethi TK1, Katalenich B2, Nagireddy P3, Chabbra P4, Kuhadiya N5, Fonseca V1.(PubMed)
(14) Acne in hirsute women by Lumezi BG1, Pupovci HL1, Berisha VL1, Goçi AU2, Gerqari A3.(PubMed)
(15) Obesity and polycystic ovary syndrome by Naderpoor N1, Shorakae S, Joham A, Boyle J, De Courten B, Teede HJ.(PubMed)
(16) Polycystic ovary syndrome: a complex condition with psychological, reproductive and metabolic manifestations that impacts on health across the lifespan by Teede H1, Deeks A, Moran L.(PubMed)
(17) Metabolic Evidence of Diminished Lipid Oxidation in Women With Polycystic Ovary Syndrome. by Whigham LD1, Butz DE2, Dashti H3, Tonelli M3, Johnson LK1, Cook ME2, Porter WP4, Eghbalnia HR5, Markley JL6, Lindheim SR7, Schoeller DA8, Abbott DH9, Assadi-Porter FM10.(PubMed)
(18) Risk of endometrial, ovarian and breast cancer in women with polycystic ovary syndrome: a systematic review and meta-analysis by Barry JA1, Azizia MM1, Hardiman PJ2.(PubMed)
(19) Risk of cancer among women with polycystic ovary syndrome: a Danish cohort study by Gottschau M1, Kjaer SK2, Jensen A1, Munk C1, Mellemkjaer L3.(PubMed)
(20) Polycystic ovary syndrome: metabolic consequences and long-term management by Carmina E1.(PubMed)
(21) Arterial stiffness is increased in asymptomatic nondiabetic postmenopausal women with a polycystic ovary syndrome phenotype by Armeni E1, Stamatelopoulos K, Rizos D, Georgiopoulos G, Kazani M, Kazani A, Kolyviras A, Stellos K, Panoulis K, Alexandrou A, Creatsa M, Papamichael C, Lambrinoudaki I.(PubMed)
(1246) [Clinical study of area of Jiangsu province of polycystic ovarian syndrome correlation distribution of traditional Chinese medicine syndrome type and improper diet]. [Article in Chinese] by Feng Y, Gao YP.(PubMed)
(1247) [Preliminary study on relationship of disease-syndrome-symptom of ovulatory disorder infertility based on factor analysis]. [Article in Chinese] by Li M, Ma K, Shan, J.(PubMed)
(1247a) A Comprehensive Treatment of Polycystic Ovarian Syndrome (PCOS) bny byLiqin Zhao
(1247b) Polycystic Ovary Syndrome - a TCM Perspective by Donna Dupre, L.Ac.
(1248) Spleen-yang-deficiency patients with polycystic ovary syndrome have higher levels of visfatin by Fu H, Qiu Y, Xia M, Wei F, He H, Yang L.(PubMed)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.
Polycystic Ovarian Syndrome
Unfortunately, according to studies, women with PCOs after the reproductive age, are associated to continuously increase risk of type II diabetes, with no increasingaltered glucose tolerance(20), CVD and hypertension(21).
In Traditional Chinese Medicine Perspective
While conventional medicine focus of using synthetic medication to induce ovulation and assisted artificial insemination for infertility couple, if the medicine fail, traditional Chinese medicine views polycystic ovarian syndrome in different approaches.
Polycystic ovary syndrome, according to traditional Chinese medicine is a medical condition characterized by accumulative of fluid over a prolonged period of time causes of dampness and phlegms(247a)(247b) build up on the ovaries due to the effects of vary differentiations, affecting not only the women’s menstrual cycle, but also ovulation and fertility(1247a)(247b).
Symptoms
According to statistic, most common symptoms of Chinese women with PCOs in traditional Chinese medicine include(1247)
1. Abdomen pain before menstrual onset
2. Obfuscation color
3. Cold lower abdomen
4. Insomnia
5. Fatigue
6. Eyes dark, face dark or ring lip dark, before and after menstruation
7. Chest tightness
8. Irritability
9. Depression
10. Lower abdomen pain during menstruation
11. Breast swelling
12. Etc.
Differentiation
Depending to differentiation of the diseases, PCOs according to TCM can be classified onto
A. General syndrome
1. Kidney deficiency syndrome(1246)
2. Stagnation of Qi and blood stasis(1246)
3. Dampness heat of liver(1246)(1248)
4. Stagnation of phlegm dampness syndrome(1246)
B. Single or combination syndrome
4. Kidney Yang deficiency and blood stasis(1247)
5. Kidney Yang deficiency (1247)(1248)
6. Kidney Yin deficiency and blood stasis(1147)
7. Kidney Yin deficiency and liver Qi stagnation syndrome(1247)
8. Kidney Yang deficiency and phlegm dampness stagnation(1247)
9. Kidney Yin deficiency(147)(1248)
10. Spleen-Yang deficiency (SYD)(1248)
(1246) [Clinical study of area of Jiangsu province of polycystic ovarian syndrome correlation distribution of traditional Chinese medicine syndrome type and improper diet]. [Article in Chinese] by Feng Y, Gao YP.(PubMed)
(1247) [Preliminary study on relationship of disease-syndrome-symptom of ovulatory disorder infertility based on factor analysis]. [Article in Chinese] by Li M, Ma K, Shan, J.(PubMed)
(1248) Spleen-yang-deficiency patients with polycystic ovary syndrome have higher levels of visfatin by Fu H, Qiu Y, Xia M, Wei F, He H, Yang L.(PubMed)
(1249)
Chinese Food Therapy
The Best Way to prevent, treat your disease, including Obesity
and restore your health naturally with Chinese diet
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Super foods Library, Eat Yourself Healthy With The Best of the Best Nature Has to Offer
References
(1) Adiposity and metabolic dysfunction in polycystic ovary syndrome by Sam S.(PubMed)
(2) A "kiss" before conception: triggering ovulation with kisspeptin-54 may improve IVF by Young SL.(PubMed)
(3.) Androgen hyperfunction and excessive heterosexual hair growth in women, with special attention to the polycystic ovarian syndrome by Lunde O1.(PubMed)
(4) Expression of anti-Müllerian hormone in letrozole rat model of polycystic ovary syndrome by Du DF1, Li XL, Fang F, Du MR.(PubMed)
(5) [Serum levels of anti-muller hormone in women with polycystic ovary syndromeand healthy women of reproductive age].[Article in Bulgarian] by Parahuleva N, Pehlivanov B, Orbecova M, Deneva T, Uchikova E.(PubMed)
(6) [Current opinions on the etiology and pathophysiology of hirsutism].[Article in Polish] by Krysiak R1, Kedzia A, Okopień B.(PubMed)
(7) The clinical evaluation of hirsutism by Somani N1, Harrison S, Bergfeld WF.(PubMed)
(8) Polycystic ovary syndrome and insulin: our understanding in the past, present and future by Mayer SB1, Evans WS, Nestler JE.(PubMed)
(9) Association of mean platelet volume with androgens and insulin resistance in nonobese patients with polycystic ovary syndrome by Dogan BA1, Arduc A2, Tuna MM1, Karakılıc E1, Dagdelen I1, Tutuncu Y1, Berker D1, Guler S1.(PubMed)
(10) Approach to the patient: contraception in women with polycystic ovary syndrome by Yildiz BO1.(PubMed)
(11) Polycystic ovarian syndrome (PCOS): a significant contributor to the overall burden of type 2 diabetes in women by Talbott EO1, Zborowski JV, Rager JR, Kip KE, Xu X, Orchard TJ.(PubMed)
(12) Prevalence of vitamin D deficiency in Slovak women with polycystic ovary syndrome and its relation to metabolic and reproductive abnormalities by Figurová J1, Dravecká I, Javorský M, Petríková J, Lazúrová I.(PubMed)
(13) Role of Insulin Sensitizers on Cardiovascular Risk Factors in Polycystic Ovarian Syndrome: A Meta-Analysis by Thethi TK1, Katalenich B2, Nagireddy P3, Chabbra P4, Kuhadiya N5, Fonseca V1.(PubMed)
(14) Acne in hirsute women by Lumezi BG1, Pupovci HL1, Berisha VL1, Goçi AU2, Gerqari A3.(PubMed)
(15) Obesity and polycystic ovary syndrome by Naderpoor N1, Shorakae S, Joham A, Boyle J, De Courten B, Teede HJ.(PubMed)
(16) Polycystic ovary syndrome: a complex condition with psychological, reproductive and metabolic manifestations that impacts on health across the lifespan by Teede H1, Deeks A, Moran L.(PubMed)
(17) Metabolic Evidence of Diminished Lipid Oxidation in Women With Polycystic Ovary Syndrome. by Whigham LD1, Butz DE2, Dashti H3, Tonelli M3, Johnson LK1, Cook ME2, Porter WP4, Eghbalnia HR5, Markley JL6, Lindheim SR7, Schoeller DA8, Abbott DH9, Assadi-Porter FM10.(PubMed)
(18) Risk of endometrial, ovarian and breast cancer in women with polycystic ovary syndrome: a systematic review and meta-analysis by Barry JA1, Azizia MM1, Hardiman PJ2.(PubMed)
(19) Risk of cancer among women with polycystic ovary syndrome: a Danish cohort study by Gottschau M1, Kjaer SK2, Jensen A1, Munk C1, Mellemkjaer L3.(PubMed)
(20) Polycystic ovary syndrome: metabolic consequences and long-term management by Carmina E1.(PubMed)
(21) Arterial stiffness is increased in asymptomatic nondiabetic postmenopausal women with a polycystic ovary syndrome phenotype by Armeni E1, Stamatelopoulos K, Rizos D, Georgiopoulos G, Kazani M, Kazani A, Kolyviras A, Stellos K, Panoulis K, Alexandrou A, Creatsa M, Papamichael C, Lambrinoudaki I.(PubMed)
(1246) [Clinical study of area of Jiangsu province of polycystic ovarian syndrome correlation distribution of traditional Chinese medicine syndrome type and improper diet]. [Article in Chinese] by Feng Y, Gao YP.(PubMed)
(1247) [Preliminary study on relationship of disease-syndrome-symptom of ovulatory disorder infertility based on factor analysis]. [Article in Chinese] by Li M, Ma K, Shan, J.(PubMed)
(1247a) A Comprehensive Treatment of Polycystic Ovarian Syndrome (PCOS) bny byLiqin Zhao
(1247b) Polycystic Ovary Syndrome - a TCM Perspective by Donna Dupre, L.Ac.
(1248) Spleen-yang-deficiency patients with polycystic ovary syndrome have higher levels of visfatin by Fu H, Qiu Y, Xia M, Wei F, He H, Yang L.(PubMed)
General Health: Detoxification - The First Step You Must Take to Cleanse Your Body Toxins
Kyle J. Norton(Scholar, Master of Nutrients), all right reserved.
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.
American diet contains high saturated fat, trans fat, and other harmful substances such as sugar, caffeine, pesticides, additive substances and less in fruits and vegetables. These types of harmful substances is toxic. Our body's detoxifying functions try to get rid of them everyday, when they fail it causes disruption of hormone production, damaging our body's detoxification organs and weakens our immune system resulting in hormone imbalance and many chronic illness. In order to reduce the risk of such results, detoxification is necessary to rejuvenate our body by replacing the intake of those bad foods with the healthy ones.
I believe this method is easy to achieve and everybody can do it without interfering too much with their choice of foods daily.
1. Reduce intake of meat
Protein is vital for brain function but consuming too much protein will cause high cholesterol building up in the arteries and triglycerides in your blood as well as increasing abdominal fat. Meat contains 50% saturated fat and 50% unsaturated. Since we consume more meat than we need, the best way is to substitute some daily intake of fat with fish. Fish contains high amounts of omega 3 fatty acids that help to balance over-supply of omega 6 acid from meat. Omega 3 fatty acid also helps to lower levels of bad cholesterol and triglyceride resulting in weight loss and a more healthy body.
2. Reduce intake of dairy products
Dairy products such as cheese, yogurt, butter, and ice cream contains high amounts of trans fat which causes cholesterol and triglyceride building up in our arteries, blocking the transportation of oxygen to our body cells resulting in fatigue, poor concentration, memory loss as well as weakening the body immune system. It is good for your health if you can reduce some of the above dairy products with rice milk, soy milk and oat milk because these healthy products contain more nutrition and help to cleanse your body from cholesterol, triglyceride and more.
3. Reduce intake of caffeine and alcohol
Caffeine and alcohol are stimulants that help to improve the function of nervous system, increasing alertness, and concentration but high amounts of caffeine and excessive drinking of alcohol causes palpitation of the heart, reducing levels of oxygen in the bloodstream as well as nervous system break down and liver disease resulting in weakened immune system and hormone imbalance. It is better for you to reduce daily intakes of above products and replace them with herbal tea, grain beverage and green tea because these healthy products promote a strong immune system, fight radical forming and toxin cleansing. Of course, we still insist drinking a maximum of one cup of red wine for women and 2 cups for men daily to help improve circulation of blood and provide more oxygen to the body's cells.
4. Reduce intake of sugar and artificial sweetener
Sugar adds calories which if you eat more than you need, you will gain weight and cause insulin resistance that increases your risk of getting heart disease, diabetes, high blood pressure or even some types of cancer. High doses of sugar and artificial also increase the urinary excretion of calcium, leading to weaker bones. Replace some of the above with raw honey or molasses.
5. Intake less carbonated beverages
Drinking carbonated beverage forces your body to consume carbon dioxide that is a toxic chemical and has a negative effect in your heart. Long term expose of this chemical will weaken your kidney and liver function. Replace some daily intake of the above with distilled water, filter water and juices. Drink at least one cup of dark green leaf juice and top it with some carrot to make it taste better. Dark green leaf juice contains a variety of nutrients and antioxidants that are vital in cleansing heavy metals and other toxins from your body.
6. Eat more fiber
Food with fiber is an excellent choice for body cleansing, specially for cleansing the toxic chemical building up in the colon. It also helps you to lose weight because you need more calories to digest food with high fiber such as celery, broccoli, cabbage and fiber adsorbs the juices from the stomach and make you feel fullness.
Chinese Food Therapy
The Best Way to prevent, treat your disease, including Obesity
and restore your health naturally with Chinese diet
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Super foods Library, Eat Yourself Healthy With The Best of the Best Nature Has to Offer
I believe this method is easy to achieve and everybody can do it without interfering too much with their choice of foods daily.
1. Reduce intake of meat
Protein is vital for brain function but consuming too much protein will cause high cholesterol building up in the arteries and triglycerides in your blood as well as increasing abdominal fat. Meat contains 50% saturated fat and 50% unsaturated. Since we consume more meat than we need, the best way is to substitute some daily intake of fat with fish. Fish contains high amounts of omega 3 fatty acids that help to balance over-supply of omega 6 acid from meat. Omega 3 fatty acid also helps to lower levels of bad cholesterol and triglyceride resulting in weight loss and a more healthy body.
2. Reduce intake of dairy products
Dairy products such as cheese, yogurt, butter, and ice cream contains high amounts of trans fat which causes cholesterol and triglyceride building up in our arteries, blocking the transportation of oxygen to our body cells resulting in fatigue, poor concentration, memory loss as well as weakening the body immune system. It is good for your health if you can reduce some of the above dairy products with rice milk, soy milk and oat milk because these healthy products contain more nutrition and help to cleanse your body from cholesterol, triglyceride and more.
3. Reduce intake of caffeine and alcohol
Caffeine and alcohol are stimulants that help to improve the function of nervous system, increasing alertness, and concentration but high amounts of caffeine and excessive drinking of alcohol causes palpitation of the heart, reducing levels of oxygen in the bloodstream as well as nervous system break down and liver disease resulting in weakened immune system and hormone imbalance. It is better for you to reduce daily intakes of above products and replace them with herbal tea, grain beverage and green tea because these healthy products promote a strong immune system, fight radical forming and toxin cleansing. Of course, we still insist drinking a maximum of one cup of red wine for women and 2 cups for men daily to help improve circulation of blood and provide more oxygen to the body's cells.
4. Reduce intake of sugar and artificial sweetener
Sugar adds calories which if you eat more than you need, you will gain weight and cause insulin resistance that increases your risk of getting heart disease, diabetes, high blood pressure or even some types of cancer. High doses of sugar and artificial also increase the urinary excretion of calcium, leading to weaker bones. Replace some of the above with raw honey or molasses.
5. Intake less carbonated beverages
Drinking carbonated beverage forces your body to consume carbon dioxide that is a toxic chemical and has a negative effect in your heart. Long term expose of this chemical will weaken your kidney and liver function. Replace some daily intake of the above with distilled water, filter water and juices. Drink at least one cup of dark green leaf juice and top it with some carrot to make it taste better. Dark green leaf juice contains a variety of nutrients and antioxidants that are vital in cleansing heavy metals and other toxins from your body.
6. Eat more fiber
Food with fiber is an excellent choice for body cleansing, specially for cleansing the toxic chemical building up in the colon. It also helps you to lose weight because you need more calories to digest food with high fiber such as celery, broccoli, cabbage and fiber adsorbs the juices from the stomach and make you feel fullness.
Chinese Food Therapy
The Best Way to prevent, treat your disease, including Obesity
and restore your health naturally with Chinese diet
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Super foods Library, Eat Yourself Healthy With The Best of the Best Nature Has to Offer
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