Medical Advisor Journals

Friday, July 1, 2016

Food therapy - Vegetables - Spinach (Spinacia)

Spinach is an edible flowering plant in the genus Spinacia, belongs to the family of Amaranthaceae and native to central and southwestern Asia. It is considered as a healthy plant containing vary vitamins and minerals.

Nutrients
1. Carbohydrates
2. Dietary fiber
3. Fat ( Omega 3 Fatty acid)
4. Protein
5. Vitamin A (Beta corotene, lutein and zeaxanthin)
6. Folate (Vitamin B9)
7. Vitamin C
8. Vitamin E
9. Vitamin K
10. Calcium
11. Iron
12. Phosphorus
13. Magnesium
14. Potassium
15. Manganese
16. Selenium
17. Etc.

Health benefits
A. Health benefits according to studies
1. Inflammatory diseases
In the evaluation of preadministration of glycolipid extracts from spinach and itsanti-oxidative and anti-inflammatory found that The glycolipid extracts fromspinach highly contained monogalactosyl-diacylglycerol (MGDG) and diglactosyl-diacylglycerol (DGDG). In Caco-2 cells, MGDG and DGDG inhibited the production of reactive oxygen species induced by phorbol ester, according to the study of "Protective effects of glycoglycerolipids extracted from spinach on 5-fluorouracil induced intestinal mucosal injury" by Shiota A, Hada T, Baba T, Sato M, Yamanaka-Okumura H, Yamamoto H, Taketani Y, Takeda E(a)

2. Anti cancers
In the investigation of major glycoglycerolipids, including monogalactosyl diacylglycerol (MGDG), digalactosyl diacylglycerol (DGDG) and sulfoquinovosyl diacylglycerol (SQDG) found in spinach and its effect on irregular cell growth found that MGDG and SQDG have been shown to inhibit the activities of mammalian DNA polymerases, but DGDG has no such inhibitory effect. The effect of these glycoglycerolipids on cancer cells, angiogenesis and solid tumor growth might be mediated via their inhibition of replicative DNA polymerase activities, according to "Anti-cancer effect of spinach glycoglycerolipids as angiogenesis inhibitors based on the selective inhibition of DNA polymerase activity" by Maeda N, Matsubara K, Yoshida H, Mizushina Y.(b)

3. Antioxidants
In the observation of serum total antioxidant capacity following comsumption of strawberries (240 g), spinach (294 g), red wine (300 ml) or vitamin C (1250 mg) in eight elderly women found that oxygen radical absorbance capacity (ORAC) assay, Trolox equivalent antioxidant capacity (TEAC) assay and ferric reducing ability (FRAP) assay. The results showed that the total antioxidant capacity of serum determined as ORAC, TEAC and FRAP, using the area under the curve, increased significantly by 7-25% during the 4-h period following consumption of red wine, strawberries, vitamin C or spinach. showed that the total antioxidant capacity of serum determined as ORAC, TEAC and FRAP, using the area under the curve, increased significantly by 7-25% during the 4-h period following consumption of red wine, strawberries, vitamin C or spinach, according to "Serum antioxidantcapacity is increased by consumption of strawberries, spinach, red wine or vitamin C in elderly women" by Cao G, Russell RM, Lischner N, Prior RL.(c)

4. Bone health
In the investigation of bone mass level associated with lifestyle factors among young Japanese women anf their effect in bone mass found that without daily intake of green and yellow vegetables had almost 5-fold risk of low bone mass, compared to the subjects having daily intake of the vegetables [Odds ratio: 4.96 (95%CI 1.36-18.18)]. In conclusion, daily intake of green and yellow vegetables is effective for maintaining bone mass in young women, according to "Daily intake of green and yellow vegetables is effective for maintaining bone mass in young women" by Fujii H, Noda T, Sairenchi T, Muto T.(d)

5. Etc.

B. Health benefits according to concentration
1. Vitamin K
Vitamin K not only plays an important role in protecting our skin from aging, it is also needed for the proper clotting of blood, thus decreasing the risk of excessive bleeding, in a study of "Delayed vitamin K deficiency as a cause of bleeding: still a concern in the 21st century!" by Kasatkar P, Shetty S, Ghosh K., posted inPubMed, researchers found that Laboratory tests confirmed acquired bleeding diathesis due to vitamin K deficiency, which was corrected after adequate vitamin K supplementation. VKDB is not an uncommon phenomenon and should be considered in the differential diagnosis of a child with bleeding diathesis.

2. Vitamin A
Vitamin A is not only important in preventing types I diabetes, according to "A close relationship between type 1 diabetes and vitamin A-deficiency and matrix metalloproteinase and hyaluronidase activities in skin tissues" byTakahashi N, Takasu S.(1) but also may be associated with compromised bone health, according to "Vitamins and bone health: beyond calcium and vitamin D" by Ahmadieh H, Arabi A.(2)

Manganese
It is one of important trace in preventing osteoporosis, according to the study of "[Study of estrogen deficiency impact on manganese levels in teeth and mandible of rats after ovariectomy]. [Article in Polish]" by Rahnama M, Błoniarz J, Zareba S, Swiatkowski W.(1)and regulating blood sugar level, according to the study of "[An inadequate intake of manganese may favour insulin resistance in girls]. [Article in Spanish]" by Rodríguez-Rodríguez E, Bermejo LM, López-Sobaler AM, Ortega RM.(5)

4. Folate
In the investigation of the prevalence and multifactorial etiology of anemia among Indian human immunodeficiency virus (HIV)-infected children and its effect onanemia, found that Anemia, particularly iron deficiency anemia and anemia of inflammation, is highly prevalent among children with HIV infection. Micronutrient supplements (iron and, folate) combined with ART(antiretroviral therapy) improved anemia in HIV-infected children, according to "The prevalence and etiology of anemia among HIV-infected children in India" by Shet A, Arumugam K, Rajagopalan N, Dinakar C, Krishnamurthy S, Mehta S, Shet AS.(4)

5. Etc.

C. Other health benefits
1. Phytonutrients
a) Immune system
Phytonutrients help to improve the immune system in fighting against the forming of free radicals that cause infection, inflammation and enhance the replication of DNA and cells division, according to study of "Role of antioxidants, essential fatty acids, carnitine, vitamins, phytochemicals and trace elements in the treatment of diabetes mellitus and its chronic complications" by Triggiani V, Resta F, Guastamacchia E, Sabbà C, Licchelli B, Ghiyasaldin S, Tafaro E., posted in PubMed (http://www.ncbi.nlm.nih.gov/pubmed/16611166)

b) Breast cancer
Phytoestrogen in the spinach also helps to occupy the estrogen receptor site, that prevents
the over production of bad estrogen, causing breast cancer, according to the study of "Phytoestrogens and breast cancer: a complex story" by Helferich WG, Andrade JE, Hoagland MS., posted in PubMed(http://www.ncbi.nlm.nih.gov/pubmed/18815740), researchers found that genistein can act as an oestrogen agonist resulting in proliferation of E-dependent human breast cancer tumours in vivo.

2. Menopause
Spinach contains high amount of plant estrogen that helps to reduce the symptoms of menopause, such as bone density, hot flash, etc., according to the study of "[The role of phytoestrogen therapy in relieving postmenopausal symptoms].[Article in Polish]" by Szkutnik-Fiedler D, Jedrzejczyk M, Grześkowiak E, Bartkowiak-Wieczorek J, Seremak-Mrozikiewicz A, Drews K, Mrozikiewicz PM., posted in PubMed (http://www.ncbi.nlm.nih.gov/pubmed/21395085)

3. Colon health
Spinach contains high amount of Vitamin A, E and vitamin C that help to enhance the immune system in protecting the proper growth of the colon cell and its DNA damage and mutation from free radicals, according to the abstract of study of "Intakes of vitamins A, C, and E and use of multiple vitamin supplements and risk of colon cancer: a pooled analysis of prospective cohort studies" by Park Y, Spiegelman D, Hunter DJ, Albanes D, Bergkvist L, Buring JE, Freudenheim JL, Giovannucci E, Goldbohm RA, Harnack L, Kato I, Krogh V, Leitzmann MF, Limburg PJ, Marshall JR, McCullough ML, Miller AB, Rohan TE, Schatzkin A, Shore R, Sieri S, Stampfer MJ, Virtamo J, Weijenberg M, Willett WC, Wolk A, Zhang SM, Smith-Warner SA., posted in PubMed (http://www.ncbi.nlm.nih.gov/pubmed/20820901), researchers found that Modest inverse associations with vitamin C and E intakes may be due to high correlations with folate intake, which had a similar inverse association with colon cancer. An inverse association with multivitamin use, a major source of folate and othervitamins, deserves further study.

4. Cataracts and muscular degeneration
Spinach contains a measurable amount of lutein, that helps to protect against eye diseases including age-related cataracts and muscular degeneration, according to the study of "Associations between lutein, zeaxanthin, and age-relatedmacular degeneration: an overview" by Carpentier S, Knaus M, Suh M., posted in PubMed (http://www.ncbi.nlm.nih.gov/pubmed/19234943)

5. Iron
Iron helps to enhances the production of red blood cells and formation of hemoglobin, that enhance in adsorption of oxygen from the lung and carry nutrients to all body cells, according to the study of "[Iron deficiency and overload. Implications in oxidative stress and cardiovascular health].[Article in Spanish]" by Toxqui L, De Piero A, Courtois V, Bastida S, Sánchez-Muniz FJ, Vaquero MP., posted in PubMed, (http://www.ncbi.nlm.nih.gov/pubmed/20593115)

Etc.

Side effects
1. Oxalates
Spinach contains a measurable amounts of oxalates that can cause problem for people who have untreated kidney and gallbladder diseases.
2. Purines
Purines is naturally substances found in plants, animals, and humans, it can cause forming of uric acid if over accumulated.
3. Etc.

Chinese Food Therapy
The Best Way to prevent, treat your disease, including Obesity
and restore your health naturally with Chinese diet

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Super foods Library, Eat Yourself Healthy With The Best of the Best Nature Has to Offer

Sources
(a) http://www.ncbi.nlm.nih.gov/pubmed/20847532
(b) http://www.ncbi.nlm.nih.gov/pubmed/21034405
(c) http://www.ncbi.nlm.nih.gov/pubmed/9868185

(1) http://www.ncbi.nlm.nih.gov/pubmed/21859436
(2) http://www.ncbi.nlm.nih.gov/pubmed/21967159
(3) http://www.ncbi.nlm.nih.gov/pubmed/22072339
(4) http://www.ncbi.nlm.nih.gov/pubmed/22009132

Anti Aging: The Research and Studies of Skin Aging - The Effects of Diet

Kyle J. Norton(Scholar and Master of Nutrients, all right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.
All right reserved. Reproduction and Translation to other languages of this publication are prohibited without consent of the writer.

Who doesn't want to look 5, 10,15 or 20 years younger in comparison to people with the same age group?

The dream of finding the ingredients in rejuvenated aging skin has been ongoing since human civilization. Unfortunately, many ingredients with no commercial values have been discarded due to their effects in dampening the profits of all cosmetic companies.

Don't ask me about commercial anti-aging products. Most of them are produced for making profits and do not perform as theirs' claims. Truly, if one found to be effective, it will constitute to shelf-removal of many others with the same intention. Unfortunately, walking through the cosmetic section of health stores and super markets, thousands of these products are still packed on the shelves. How effective they are? You know the answer.

Skin aging is one of most visible ageing process which occurs constantly in our skin organ. According to the Clinical Centre of Nis, certain plant extracts may have the ability to scavenge free radicals, to protect the skin matrix through the inhibition of enzymatic degradation, or to promote collagen synthesis in the skin, affect skin elasticity and tightness(a). Other suggested that free radicals induced domino effects in production of reactive oxygen species, can react with DNA, proteins, and fatty acids, causing oxidative damage and impairment of antioxidant system, leading injuries damage regulation pathways of skin, including wrinkles, roughness, appearance of fine lines, lack of elasticity, and de- or hyperpigmentation marks(b).
The degradation of the epidermal and dermal layers of the extracellular matrix (ECM), the non-cellular component present within all tissues and organs, such as UV Exposure, decline of lysosomal/endosomal cathepsin K, S and V activity(c) as well as environment factors such as irregular dryness, dark/light pigmentation, sallowness, severe atrophy, telangiectases, premalignant lesions, laxity, leathery appearance and deep wrinkling, etc., cause modification of the surface of skinand the physical properties of that lead to skin aging. Certain foods have been found to be effective in protect the skin against natural aging, including green tea and garlic.

1. Garlic
Garlic (Allium sativum) is a species in the onion genus, belonging to family Amaryllidaceae, native to central Asia. It has been used popularly in traditional and Chinese medicine in treating common cold and flu to the Plague, blood pressure cholesterol levels, natural antibiotic, etc.
In wrinkle formation, caffeic acid and S-allyl cysteine found in garlic significantly inhibited the degradation of type І procollagen and the expressions of MMPs in vivo and attenuated the histological collagen fiber disorder and oxidative stress in vivo, through decreased oxidative stress and inflammation by modulating the activities of NF-κB and AP-1, and exhibited an indirect anti-oxidant effect by suppressing cyclooxygenase-2 (COX-2) and induced nitric oxide synthase (iNOS) expressions levels and down-regulated transcriptional factors(1). Its garlic's antioxidant properties may either prevent or delay chronic diseases associated with aging(2). According to Aarhus University, garlic not only protected skin cell from undergo aging process but also inhibited the abnormal growth of skin cells, through its on long-term growth characteristics, morphology and macromolecular synthesis of human fibroblasts(3).

2. Ginger
Ginger (Zingiber officinale) or ginger root is the genus Zingiber, belonging to the family Zingiberaceae, native to Tamil. It has been used in traditional and Chinese medicine to treat dyspepsia, gastroparesis, constipation, edema, difficult urination, colic, etc.
In formation of wrinkles induced by UV exposure in rat or hairless mouse skin,extract of Zingiber officinale, significantly inhibited the fibroblast-derived elastase at a suberythemal dose, in prevention of the decrease in skin elasticity in both types of animal skin(4).

3. Black bean
Small roughly ovoid legumes with glossy black shells, genus Phaseolus, belongs to the family Fabaceae and can bought in most grocery stores all around the year in dried and canned forms. It is believed that black bean was first domesticated growth in South America.
According to Jiangnan University, chemical constituents in black bean sprouts may potentiate as additives in anti-aging and whitening skin cosmetic products due to its antioxidant properties(5).
On UVB-induced apoptotic skin cell death, anthocyanins a major chemical compound found in black bean, not only reduced UVB-induced reactive oxygen species levels but also inhibited UVB-induced apoptotic cell death through the prevention of caspase-3 pathway activation and reduction of proapoptotic Bax protein levels(6). Other study also found the effectiveness of anthocyanins in modulation of oxidative disorders including UVB-induced inflammation(7).

4. Avocado
Avocados are a commercially valuable fruit and are cultivated in tropical climates throughout the world, it is a green-skinned, pear-shaped fruit that ripens after harvesting and native to the Caribbean, Mexico, South America and Central America, belonging to the flowering plant family Lauraceae.
Daily intake of one-half a Hass avocado (68 g), may support cardiovascular health, weight management and healthy aging(8). Study on the of ingestion of an unsaponifiable avocado and soya extract (P.I.A.S.) indicated a very probable presence of phytosterols and a richer proportion of cholesterol, precursors particularly methostenol in the skin of rats fed(9).

5. Passion fruit
Passionflower is also known as passion vines,, in the genus Passiflora ,belonging to the family Passifloraceae, native to southeastern parts of the America. The herb has been used in traditional medicine in treating nervous tension including anxiety, insomnia, seizures, sleep problems and hysteria.
Passion fruit seed extract, piceatannol, and scirpusin B effected the keratinocyte by upregulated the glutathione (GSH) levels in keratinocytes in a dose-dependent manner, and suppressed the UVB-induced generation of reactive oxygen species (ROS), and enhanced matrix-metalloproteinase (MMP)-1 activity(10). A flavone chrysin from Passiflora caerulea Linn. and a benzoflavone moiety (BZF) recently isolated from Passiflora incarnata Linn in rat skin study, showed a great potential for clinical and therapeutic applications against the physiological and biochemical effects of aging(11).

6. Mango
Mango tree is a flower plant of genus of Mangifera, belonging to the family Anacardiaceae, native to the subtropical and tropical southeast Asia. The
Beside exerting its antioxidant with anti-inflammatory and immunomodulatory activities, mango extract also showed to inhibit wrinkle formation and damage to collagen fiber against UVB-induced skin aging in hairless mice(12). Polyamine, a major chemical constituent of mango and other plants may be potential target for reduced aging skin as the level of spermidine was maximal in 10-week-old mice and markedly reduced in 26-week-old mice(13).

7. Apple
Apple is the pomaceous fruit of the apple tree, a species of the rose family Rosaceae. It is one of the most widely cultivated tree fruits. The tree is originated in Central Asia.
Apple whole fruit and its chemical compound showed to protect cells from agingthrough influence of aging and oxidative stress(14). The study from Taipei Medical University, in the study of its chemical compounds suggested the use of extract of M. doumeri var. formosana (containing phenolic compounds) in anti-aging or cosmetic products(15) through exhibition of anti-oxidant and tyrosinase reducing activities(16).

9. Sea buckthorn fruit
Sea buckthorn is a shrub in the genus Hippophae, belonging to the family Elaeagnaceae, native to in
the wide regions of the Atlantic coasts of Europe right across to northwestern Mongolia and also
northwestern China.
A sea buckthorn (Hippophae rhamnoides L.) fruit blend (SFB) containing sea buckthorn fruit extract,
exhibited a protective and therapeutic drug candidate against skin aging by regulating the moisture
content, MMP expression levels and SOD activity in UV radiation-induced skin aging in hairless mice,
according to the study by the Pusan National University(17).

10. Grape
Grape is a woody vines of the genus Vitis, belong to the family Vitaceae, native to southern Turkey.
Trans-resveratrol, a polyphenol extracted from grape, showed a remarkable improvement in decreased aging signs(18). In facial skin morphology and functionality, combination of grape seed extract and soy phospholipids showed to have the potential in induced signal transduction pathways in facial hypodermis, resulting in anti-aging effects throughout all skin compartments, including dermal and epidermal layers(19). Clinically and biometrically, composition of lycopene, acerola extract, grape seed extract and Biomarine ComplexT showed to increase parameters of cutaneous hydration, reduction of pH, ultrasound density and a histological increment of collagen and elastic fibers (both on the face and arm), through a reduction of seborrhea (only on the face)(20).

11. Pomegranate
Pomegranates is a fruit-bearing small tree, genus Punica, belonging to family Lythraceae, native to Iran but has been cultivated in Asian since ancient time.
Pomegranate are among many plants ma be beneficial in protect against human skin aging(21), In the
Study at the Kyung Hee University Global Campus, Punica granatum (pomegranate) extract showed a positive effect in protecting skin against UVB-induced damage in cultured human skin fibroblasts, through increased expression of procollagen type I and decreased expression of MMP-1(22). In an immortal human keratinocyte line (Hala cell line), pomegranate polyphenol extract POMx protected HaCaT cells against UVB-induced oxidative stress and markers of photoaging(23). Ellagic acid, a polyphenol compound presented in berries andpomegranate, prevented collagen destruction and inflammatory responses caused by UV-B, according to the Hallym University(24).

12. Almond skin
Almond consists of an outer hull and a hard shell with the seed (nut) inside is native to the Middle East. It is most widely cultivated seed in the world for it economic and health benefit.
The study of α-Tocopherol (AT) and polyphenols (AP) in almonds ahainst UV exposure causes of oxidative stress, inflammation, erythema, and skin cancer, showed the positive effect of AT and AP, applied to medium or topically, in photoprotection against UVA(25)(26).

13. Cacao bean and cola nut
Caocao a small tropical American evergreen tree, of the genus Theobroma, belonging to the family Malvaceae. Its seed has been used for making chocolate and cocoa mass, cocoa powder.
Cola tree is a genus Cola, belonging the family Malvaceae, native to the tropical rainforests of Africa.
Topical application of plant extracts and their xanthine derivatives showed to suppressed wrinkle formation, dermal connective alteration, and collagen accumulation(27). The 1Natura Innovation and Product Technology Ltda, Cajamar study indicated the antioxidant effects of cacao in protection against oxidative causes of skin cell damage(28).

14. Olive oils
Olive is belongs to the the family Oleaceae, native to the coastal areas of the eastern Mediterranean Basin and south end of the Caspian Sea. Its fruit, is also called the olive and the source of olive oil.
Unsaturated fatty acid (PUFA) found abundantly in olive oil may be effective in alleviation of skin problems such as dryness and those related to the agingprocess. The Università degli Studi di Torino study showed the use of combination of hemp seed and olive oils may inhibit the problem through spraying in some gel-emulsions(29). According to the Procter & Gamble Company, olive-derived fatty acid ethoxylates, not only showed to restore antioxidant enzymes in skinkeratinocytes and fibroblasts, but also reduced melanin production by an adrenergic receptor mechanism in melanocytes(30).

15. Date palm kernel extract
Date palm tree is a genus of Phoenix, belonging to the familyArecaceae, native from lands around Iraq. According to Vincience Research Center Date palm kernel
extract, in the study of 10 Ten healthy women volunteers, between the ages of 46 and 58 years, applied
the cream formula with 5% date palm kernel or placebo on the eye area twice a day for 5 weeks,
application of date palm kernel reduced the total surface of wrinkles by 27.6% (p = 0.038), the depth of
wrinkles by 3.52% (p = 0.0231). These results are statistically significant and were clinically confirmed
where visual improvement was seen in 60% of the volunteers treated(31).

16. Lemon oil
Lemon is a species of Citrus Aurantifolia, belongs to the family Rutaceae. It has around shape are with green to yellow in color and 3–6 cm in diameter and native to Southeast Asia.
According to University of Catania, Italy, a natural compound isolated from lemon oil (Lem1) not only showed to significantly increase the antioxidative potential ofskin biosurface in healthy volunteers but lexhibited a strong antioxidant effects in inhibition of free radical-mediated reactions, as evaluated in vitro and in vivo(32) and may provide a better understanding of the endogenous antioxidant potential ofskin and the real validity of a natural antioxidant biotechnology in the antiaging management of the skin(33).

Taken altogether, the list of foods have been found effectively in protection of photoagingnd alleviation of skin symptoms due to aging, as well as through influence of the expression of procollagen type I and MMP-1. As always, all articles written by Kyle J. Norton are for information & education only, please consult your Doctor & Related field specialist before applying.

Chinese Food Therapy
The Best Way to prevent, treat your disease, including Obesity
and restore your health naturally with Chinese diet

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Super foods Library, Eat Yourself Healthy With The Best of the Best Nature Has to Offer

References
(1) Anti-wrinkle and anti-inflammatory effects of active garlic components and the inhibition of MMPs via NF-κB signaling by Kim SR1, Jung YR, An HJ, Kim DH, Jang EJ, Choi YJ, Moon KM, Park MH, Park CH, Chung KW, Bae HR, Choi YW, Kim ND, Chung HY(PubMed)
(2) Garlic and aging: new insights into an old remedy by Rahman K(PubMed)
(3) Testing garlic for possible anti-ageing effects on long-term growth characteristics, morphology and macromolecular synthesis of human fibroblasts in culture by Svendsen L1, Rattan SI, Clark BF.(PubMed)
(4) Inhibition of ultraviolet-B-induced wrinkle formation by an elastase-inhibiting herbal extract: implication for the mechanism underlying elastase-associated wrinkles by Tsukahara K1, Nakagawa H, Moriwaki S, Takema Y, Fujimura T, Imokawa G(PubMed)
(5) Study of active ingredients in black soybean sprouts and their safety in cosmetic use by Lai J1, Xin C, Zhao Y, Feng B, He C, Dong Y, Fang Y, Wei S.(PubMed)
(6) Protective effect of anthocyanins from black soybean seed coats on UVB-induced apoptotic cell death in vitro and in vivo by Tsoyi K1, Park HB, Kim YM, Chung JI, Shin SC, Shim HJ, Lee WS, Seo HG, Lee JH, Chang KC, Kim HJ.(PubMed)
(7) Anthocyanins from black soybean seed coats inhibit UVB-induced inflammatory cylooxygenase-2 gene expression and PGE2 production through regulation of the nuclear factor-kappaB and phosphatidylinositol 3-kinase/Akt pathway by Tsoyi K1, Park HB, Kim YM, Chung JI, Shin SC, Lee WS, Seo HG, Lee JH, Chang KC, Kim HJ.(PubMed)
(8) Hass avocado composition and potential health effects by Dreher ML1, Davenport AJ.(PubMed)
(9) [Influence of the daily ingestion of a total unsaponifiable extract from avocadoand soy bean oils on cholesterol metabolism in the rat].[Article in French] by Chevallier F, Lutton C, Sulpice JC, D'Hollander F.(PubMed)
(10) The protective effects of piceatannol from passion fruit (Passiflora edulis) seeds in UVB-irradiated keratinocytes by Maruki-Uchida H1, Kurita I, Sugiyama K, Sai M, Maeda K, Ito T.(PubMed)
(11) Beneficial effects of chrysin and benzoflavone on virility in 2-year-old male rats by Dhawan K1, Kumar S, Sharma A.(PubMed)
(12) Protective effect of mango (Mangifera indica L.) against UVB-induced skin aging in hairless mice by Song JH1, Bae EY, Choi G, Hyun JW, Lee MY, Lee HW, Chae S.(PubMed)
(13) Decrease in polyamines with aging and their ingestion from food and drink by Nishimura K1, Shiina R, Kashiwagi K, Igarashi K.(PubMed)
(14) Apple can act as anti-aging on yeast cells by Palermo V1, Mattivi F, Silvestri R, La Regina G, Falcone C, Mazzoni C.(PubMed)
(15) Phenolic constituents of Malus doumeri var. formosana in the field of skincare. by Leu SJ1, Lin YP, Lin RD, Wen CL, Cheng KT, Hsu FL, Lee MH(PubMed)
(16) Constituents from the Formosan apple reduce tyrosinase activity in human epidermal melanocytes by Lin YP1, Hsu FL, Chen CS, Chern JW, Lee MH(PubMed)
(17) UV radiation-induced skin aging in hairless mice is effectively prevented by oral intake of sea buckthorn (Hippophae rhamnoides L.) fruit blend for 6 weeks through MMP suppression and increase of SOD activity by Hwang IS1, Kim JE, Choi SI, Lee HR, Lee YJ, Jang MJ, Son HJ, Lee HS, Oh CH, Kim BH, Lee SH, Hwang DY.(PubMed)
(18) Enhanced antioxidant effect of trans-resveratrol: potential of binary systems with polyethylene glycol and cyclodextrin by Moyano-Mendez JR1, Fabbrocini G, De Stefano D, Mazzella C, Mayol L, Scognamiglio I, Carnuccio R, Ayala F, La Rotonda MI, De Rosa G(PubMed)
(19) Hypodermal delivery of cosmetic actives for improved facial skin morphology and functionality by Bojanowski K.(PubMed)
(20) Clinical, biometric and ultrasound assessment of the effects of daily use of a nutraceutical composed of lycopene, acerola extract, grape seed extract and Biomarine Complex in photoaged human skin by Costa A1, Lindmark L, Arruda LH, Assumpção EC, Ota FS, Pereira Mde O, Langen SS(PubMed)
(21) Innovations in natural ingredients and their use in skin care by Fowler JF Jr1, Woolery-Lloyd H, Waldorf H, Saini R(PubMed)
(22) Extract of Punica granatum inhibits skin photoaging induced by UVB irradiation by Park HM1, Moon E, Kim AJ, Kim MH, Lee S, Lee JB, Park YK, Jung HS, Kim YB, Kim SY(PubMed)
(23) Inhibition of UVB-mediated oxidative stress and markers of photoaging in immortalized HaCaT keratinocytes by pomegranate polyphenol extract POMx by Zaid MA1, Afaq F, Syed DN, Dreher M, Mukhtar H.(PubMed)
(24) Dietary compound ellagic acid alleviates skin wrinkle and inflammation induced by UV-B irradiation by Bae JY1, Choi JS, Kang SW, Lee YJ, Park J, Kang YH(PubMed)
(25) A pilot study of the photoprotective effect of almond phytochemicals in a 3D human skin equivalent by Evans-Johnson JA1, Garlick JA, Johnson EJ, Wang XD, Oliver Chen CY.(PubMed)
(26) Effect of pre-treatment of almond oil on ultraviolet B-induced cutaneous photoaging in mice by Sultana Y1, Kohli K, Athar M, Khar RK, Aqil M.(PubMed)
(27) Topical application of plant extracts containing xanthine derivatives can prevent UV-induced wrinkle formation in hairless mice by Mitani H1, Ryu A, Suzuki T, Yamashita M, Arakane K, Koide(PubMed)
(28) A new potent natural antioxidant mixture provides global protection against oxidative skin cell damage by Jorge AT1, Arroteia KF, Lago JC, de Sá-Rocha VM, Gesztesi J, Moreira PL(PubMed)
(29) Hemp-seed and olive oils: their stability against oxidation and use in O/W emulsions.
Sapino S1, Carlotti ME, Peira E, Gallarate M(PubMed)
(30) Application of genomics to breakthroughs in the cosmetic treatment of skinageing and discoloration by Osborne R1, Hakozaki T, Laughlin T, Finlay DR.(PubMed)
(31) Date palm kernel extract exhibits antiaging properties and significantly reduces skin wrinkles by Bauza E1, Dal Farra C, Berghi A, Oberto G, Peyronel D, Domloge N(PubMed)
(32) Oxidative stress and antioxidants at skin biosurface: a novel antioxidant fromlemon oil capable of inhibiting oxidative damage to the skin by Calabrese V1, Scapagnini G, Randazzo SD, Randazzo G, Catalano C, Geraci G, Morganti P(PubMed)
(33) Biochemical studies on a novel antioxidant from lemon oil and its biotechnological application in cosmetic dermatology by Calabrese V1, Randazzo SD, Catalano C, Rizza V.(PubMed)

Women Health: Fibroadenomas Preventions - The Diet

1. Cruciferous vegetables
Cruciferous vegetables such as cauliflower, broccoli, cabbage, etc. beside contain high amount of antioxidants, but also phytonutrients that have been shown to help prevent the onset and halt the progression of certain invasive tumors.

2. Wolfberry
Wolfberry beside contains a measure amount of beta-carotene which is proven in vitro to inhibit the spreading of cancer cells, it also contains high amount of phytonutrient which can occupy the estrogen receptors, leading to less estrogen produced by the body. Because of controversy of the subject, I would like to direct the question to this site, click here

3. Deep sea fish
Deep sea fish, because of living in the very cold environment and feeding onto omega 3 rich seaweed, contains high amount of Omega 3 essential fatty acid which is necessary to balance the levels of Omega 6 fatty acids to prevent the over production of prostaglandins hormone, causing premenstrual mastalgia, leading to fibroadenomas.

4. Green tea
In some clinical studies researchers suggested that the polyphenols in green tea, may play an important role in the prevention of cancer by killing cancerous cells and stopping their progression. It should helpful to prevent breast cancer due to fibroadenomas.

5. Fruits and vegatable
In a study of Fruit and vegetable intakes are associated with lower risk of breast fibroadenomas in Chinese women. Nelson ZC, Ray RM, Wu C, Stalsberg H, Porter P, Lampe JW, Shannon J, Horner N, Li W, Wang W, Hu Y, Gao D, Thomas DB, researchers found that In conclusion, a diet rich in fruits and vegetables and the use of oral contraceptives may reduce risk of fibroadenoma.

6. Etc.

Chinese Food Therapy
The Best Way to prevent, treat your disease, including Obesity
and restore your health naturally with Chinese diet

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Super foods Library, Eat Yourself Healthy With The Best of the Best Nature Has to Offer

General Health: Depression - The General Approach for Prevention

Prevention - The General Approach

1. Reduce intake of saturated and trans fats
Saturates and trans fats cause the increase of levels of bad cholesterol in the blood stream, blocking the circulation of blood and reducing the levels of oxygen that are essential for brain cells resulting in mood change and low interest for daily function.

2. Reduce intake of fat food, simple carbohydrates, and artificial sweetener
The above food causes chemical and nutritional imbalances and contribute to depression.

3. Be careful with conventional prescription side effects
Conventional medication while common can produce negative side effects and tends to treat the symptoms rather than the cause of depression. Some prescription medication may cause side effects to only some patients but not others. Be sure to talk to your doctor if you have some depression side effect.

4. Moderate exercise
Exercise helps to increase the circulation and oxygen level in the bloodstream, gives body energy and produces feelings of revitalization and accomplishmenttriggering the release of certain hormones that help to boost your mood.

5. Join a social group or club
Joining a social group or club is the best way to climb out and learn something new. It is the proven way to keep your brain active and increase your confidence and self esteem.

6. Get enough sleep
Over half of people with sleep disorders are found to have some mental disorder such as depression. In fact, study shows that insomnia may be the cause of depression.

7. Light therapy
If you have season affective disorder, the body chemistry is thrown off by a decrease in the amount of day light. Light therapy will help to increase energy levels and overcome difficulty in getting out of bed.

The Obesity' Research and Studies of Intermittent versus daily calorie restriction

Kyle J. Norton(Scholar, Master of Nutrients), all right reserved.
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

Obesity is a medical condition of excess body fat accumulated overtime, while overweight is a condition of excess body weight relatively to the height. According to the Body Mass Index(BMI), a BMI between 25 to 29.9 is considered over weight, while a BMI of over 30 is an indication of obesity. According to the statistic, 68% of American population are either overweight or obese.

You can calculate your BMI index BMI= weight (kg)/ height (m2)

The Studies of Intermittent versus daily calorie restriction

Dietary restriction is an effective strategy for weight loss in obese individuals.The most common form of dietary restriction implemented is daily calorie restriction (CR), which involves reducing energy by 15-60% of usual caloric intake every day. Another form of dietary restriction employed is intermittent CR, which involves 24 h of ad libitum food consumption alternated with 24 h of complete or partial food restriction. The study reveal that similar weight loss and fat mass loss with 3 to 12 weeks' intermittent CR (4-8%, 11-16%, respectively) and daily CR (5-8%, 10-20%, respectively). In contrast, less fat free mass was lost in response to intermittent CR versus daily CR.(1)

Chinese Food Therapy
The Best Way to prevent, treat your disease, including Obesity
and restore your health naturally with Chinese diet

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Super foods Library, Eat Yourself Healthy With The Best of the Best Nature Has to Offer

(1) "Intermittent versus daily calorie restriction: which diet regimen is more effective for weight loss?"

The Obesity's Weight Loss Recipes - Hummus

Kyle J. Norton(Scholar, Master of Nutrients), all right reserved.
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

The Best Weight Loss and Healthy Recipe - Hummus

Recipe contributed by 30 minutes vegetarian recipes by Marie-laude Morin, Publisher Robert Rose at www,robertrose.ca

Using canned chickpeas means you can prepare this hummus in just a few Minutes with no cooking required. Serve with toasted pita chips.
Tips: this recipe can be lighter by replacing 1 tbsp. (15mL) olive oil with the same amount of water. It's just as tasty. For presentation, drizzle a little olive oil on top and sprinkle with fresh parsley.
Food processor
11/2 cup drained rinsed canned chickpeas (375mL)
1 clove garlic, coarsely chopped 1
3 tbsp. freshly squeezed lemon juice (45mL)
1 tbsp. olive oil (15mL)
1 tbsp. tahini (15mL)
1/2 tsp. salt (2mL)
Freshly ground pepper
In a food processor, puree chickpeas, garlic, lemon juice, olive oil, 3 tbsp. (45mL) water, tahini and pepper to taste, until smooth and creamy.
Variation: Fresh herb hummus: Add 2 tbsp. (30mL) fresh Italian flat-leaf parsley leaves, 6 fresh basil leaves and 2 tsp. (10mL) thyme leaves with chickpeas. Make 12.

Chinese Food Therapy
The Best Way to prevent, treat your disease, including Obesity
and restore your health naturally with Chinese diet

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Super foods Library, Eat Yourself Healthy With The Best of the Best Nature Has to Offer

The Holistic prevention, management and treatment of Polycystic Ovarian Syndrome: TCM Herbal Medicine for Kidney Yang deficiency -Wolfberry

Polycystic Ovarian Syndrome is defined as endocrinologic diseases among reproductive-age women caused by undeveloped follicles clumping on the ovaries that interferes with the function of the normal ovaries associated with a high risk for metabolic disorder(1) as resulting of enlarged ovaries(2), leading to hormone imbalance(excessive androgen and anti-müllerian hormone (AMH) )(1)(3)(4)(5), induced Hirsutism(6)(7), reproductive disorder(10(12)), risks of type 2 diabetes(9)(10)(11), metabolic syndrome(10)(12) and early cardiovascular disease(8)(13), acne(10)(14), endometrial cancer(18)(19),weight gain and obesity(15)(16)(17). The syndrome effects over 5% of women population or 1 in 20 women.
Unfortunately, according to studies, women with PCOs after the reproductive age, are associated to continuously increase risk of type II diabetes, with no increasingaltered glucose tolerance(20), CVD and hypertension(21).

Management and Treatment according to Traditional Chinese Medicine Perspective

While conventional medicine focus of using synthetic medication to induce ovulation and assisted artificial insemination for infertility couple, if the medicine fail, traditional Chinese medicine views polycystic ovarian syndrome in different approaches.

Polycystic ovary syndrome, according to traditional Chinese medicine is a medical condition characterized by accumulative of fluid over a prolonged period of time causes of dampness and phlegms(1247a)(1247b) build up on the ovaries due to the effects of vary differentiations, affecting not only the women’s menstrual cycle, but also ovulation and fertility(1247a)(1247b).

Depending to differentiation, most common diagnosis of polycystic ovary syndrome can be classified into

Kidney yang deficiency

Along with common symptoms mentioned above, women with PCOs diagnosed with kidney yang deficiency may also experience yang vacuity induced cold expressive syndrome, including
lumbago, cold limbs, fatigue, cold aversion, feverish sensation in chest, palms and soles(1573),
difficulty in urination, enuresis, incontinence, declining libido and edema(1574) as a result of kidneys no longer perform their function in store fluid to moister and warm the body for healthy function in the body's organs and tissues, inducing adrenal insufficient chronic lower back pain(1575)(1580), depression(1575), hypothyroidism(1579)(1575), nephritis(1578)(1575), ...(1575), leading to failure in transform damp heat expression, promoted accentuation of inflammatory development of phlegm(1583).
Kidney yang deficiency has shown to alter carbohydrate and lipid metabolisms (free fatty acids, 1-monolinoleoylglycerol, and cholesterol), gut microbiota metabolism (indole-3-propionic acid), indued anovulatory infertility( 1581) and hypertension(1582) of which related to symptoms of PCOs(1576)(1577).

Herbal medicine for kidney yang deficiency

4. Lycium chinense(Qi Zi)(1759)
Gou Qi Zi or Qi Zi is also known as wolfberry fruit. The sweet and neutral herb has been used in TCM as anti cancer(1748)(1749)(1750), antiviral(1751), and antiinflammatory(1751) agent and to treat weakness(1768) mental acuity(1768), shortness of breath(1768), memory and neurogenesis impairments(1752), relieve pain(1753) improve vision(1754)(1755), anemia(1754), diabetes(1756), promote antiaging(1757), enhance immune system(1751), heart function(1751), lower blood lipids(1751), modulate estrogen receptors(1750) etc., as it nourishes and tonifies liver and kidneys by enhancing the functions of liver, lung and kidney channels(1758).

Chemical constituents(1758)
1. Betaine
2. β-sitosterol
3. Linoleic acid
4. Physalien
5. Cryptoxanthin
6. Atropine
7. Hyoscyamine
8. Scopoletin
9. Amino acids
10. Physalein
11. Zeaxanthin
12. Dipalmitate
13. Carotene
14. Etc.

Epidemiologically, wolfberry also processed anti oxidant(1763)(1762) and anti inflammatory(1765)(1764), anti insulin resistance(1760)(1761), anti depression(1767), sleep disorder(1768), anti stress(1768), anti mental deficits(1768) and anti metabolic syndrome(1766), through its enhanced carbohydrate(1770), lipid(1766) and other metabolic(1766) mechanisms, including fasting glucose(1770), hypertensive(1771)(1772), anti hyperglycaemic(1769)(1770)(1774), anti hyperlipidemic(1773)(1774), weight gain(1770), obesity, ,,, of which induced protective effects against the development of diabetes(1775)(1776) and cardiovascular disease(1777)(1751)(1778).

Chinese Food Therapy
The Best Way to prevent, treat your disease, including Obesity
and restore your health naturally with Chinese diet

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Super foods Library, Eat Yourself Healthy With The Best of the Best Nature Has to Offer

References
(1) Adiposity and metabolic dysfunction in polycystic ovary syndrome by Sam S.(PubMed)
(2) A "kiss" before conception: triggering ovulation with kisspeptin-54 may improve IVF by Young SL.(PubMed)
(3.) Androgen hyperfunction and excessive heterosexual hair growth in women, with special attention to the polycystic ovarian syndrome by Lunde O1.(PubMed)
(4) Expression of anti-Müllerian hormone in letrozole rat model of polycystic ovary syndrome by Du DF1, Li XL, Fang F, Du MR.(PubMed)
(5) [Serum levels of anti-muller hormone in women with polycystic ovary syndrome and healthy women of reproductive age].[Article in Bulgarian] by Parahuleva N, Pehlivanov B, Orbecova M, Deneva T, Uchikova E.(PubMed)
(6) [Current opinions on the etiology and pathophysiology of hirsutism].[Article in Polish] by Krysiak R1, Kedzia A, Okopień B.(PubMed)
(7) The clinical evaluation of hirsutism by Somani N1, Harrison S, Bergfeld WF.(PubMed)
(8) Polycystic ovary syndrome and insulin: our understanding in the past, present and future by Mayer SB1, Evans WS, Nestler JE.(PubMed)
(9) Association of mean platelet volume with androgens and insulin resistance in nonobese patients with polycystic ovary syndrome by Dogan BA1, Arduc A2, Tuna MM1, Karakılıc E1, Dagdelen I1, Tutuncu Y1, Berker D1, Guler S1.(PubMed)
(10) Approach to the patient: contraception in women with polycystic ovary syndrome by Yildiz BO1.(PubMed)
(11) Polycystic ovarian syndrome (PCOS): a significant contributor to the overall burden of type 2 diabetes in women by Talbott EO1, Zborowski JV, Rager JR, Kip KE, Xu X, Orchard TJ.(PubMed)
(12) Prevalence of vitamin D deficiency in Slovak women with polycystic ovary syndrome and its relation to metabolic and reproductive abnormalities by Figurová J1, Dravecká I, Javorský M, Petríková J, Lazúrová I.(PubMed)
(13) Role of Insulin Sensitizers on Cardiovascular Risk Factors in Polycystic Ovarian Syndrome: A Meta-Analysis by Thethi TK1, Katalenich B2, Nagireddy P3, Chabbra P4, Kuhadiya N5, Fonseca V1.(PubMed)
(14) Acne in hirsute women by Lumezi BG1, Pupovci HL1, Berisha VL1, Goçi AU2, Gerqari A3.(PubMed)
(15) Obesity and polycystic ovary syndrome by Naderpoor N1, Shorakae S, Joham A, Boyle J, De Courten B, Teede HJ.(PubMed)
(16) Polycystic ovary syndrome: a complex condition with psychological, reproductive and metabolic manifestations that impacts on health across the lifespan by Teede H1, Deeks A, Moran L.(PubMed)
(17) Metabolic Evidence of Diminished Lipid Oxidation in Women WithPolycystic Ovary Syndrome. by Whigham LD1, Butz DE2, Dashti H3, Tonelli M3, Johnson LK1, Cook ME2, Porter WP4, Eghbalnia HR5, Markley JL6, Lindheim SR7, Schoeller DA8, Abbott DH9, Assadi-Porter FM10.(PubMed)
(18) Risk of endometrial, ovarian and breast cancer in women with polycystic ovary syndrome: a systematic review and meta-analysis by Barry JA1, Azizia MM1, Hardiman PJ2.(PubMed)
(19) Risk of cancer among women with polycystic ovary syndrome: a Danish cohort study by Gottschau M1, Kjaer SK2, Jensen A1, Munk C1, Mellemkjaer L3.(PubMed)
(20) Polycystic ovary syndrome: metabolic consequences and long-term management by Carmina E1.(PubMed)
(21) Arterial stiffness is increased in asymptomatic nondiabetic postmenopausal women with a polycystic ovary syndrome phenotype by Armeni E1, Stamatelopoulos K, Rizos D, Georgiopoulos G, Kazani M, Kazani A, Kolyviras A, Stellos K, Panoulis K, Alexandrou A, Creatsa M, Papamichael C, Lambrinoudaki I.(PubMed)
(1246) [Clinical study of area of Jiangsu province of polycystic ovarian syndrome correlation distribution of traditional Chinese medicine syndrome type and improper diet]. [Article in Chinese] by Feng Y, Gao YP.(PubMed)
(1247) [Preliminary study on relationship of disease-syndrome-symptom of ovulatory disorder infertility based on factor analysis]. [Article in Chinese] by Li M, Ma K, Shan, J.(PubMed)
(1247a) A Comprehensive Treatment of Polycystic Ovarian Syndrome (PCOS) byLiqin Zhao

(1748) Lycium barbarum polysaccharides induce apoptosis in human prostate cancer cells and inhibits prostate cancer growth in a xenograft mouse model of human prostate cancer by Luo Q1, Li Z, Yan J, Zhu F, Xu RJ, Cai YZ.(PubMed)
(1749) [Observation of the effects of LAK/IL-2 therapy combining with Lycium barbarum polysaccharides in the treatment of 75 cancer patients]. [Article in Chinese] by Cao GW1, Yang WG, Du P.(PubMed)
(1750) Lycium barbarum inhibits growth of estrogen receptor positive human breast cancer cells by favorably altering estradiol metabolism by Li G1, Sepkovic DW, Bradlow HL, Telang NT, Wong GY.(PubMed)
(1751) An evidence-based update on the pharmacological activities and possible molecular targets of Lycium barbarum polysaccharides by Cheng J1, Zhou ZW2, Sheng HP3, He LJ4, Fan XW5, He ZX6, Sun T7, Zhang X8, Zhao RJ9, Gu L10, Cao C2, Zhou SF11.(PubMed)
(1752) Lycium barbarum polysaccharides prevent memory and neurogenesis impairments in scopolamine-treated rats by Chen W1, Cheng X2, Chen J3, Yi X2, Nie D4, Sun X5, Qin J2, Tian M2, Jin G2, Zhang X2.(PubMed)
(1753) [Effects of lycium barbarum polysaccharide on formation of traumatic neuroma and pain after transection of sciatic nerve in rats]. [Article in Chinese] by Fan H1, Deng C, Fu J, Ding L, Yin G, Ma Y.(PubMed)
(1754) Lycium (Lycium barbarum) by Cassileth B1.(PubMed)
(1755) Goji berry effects on macular characteristics and plasma antioxidant levels by Bucheli P1, Vidal K, Shen L, Gu Z, Zhang C, Miller LE, Wang J.(PubMed)
(1756) Anti-diabetic effects of the ethanol extract of a functional formula diet in mice fed with a fructose/fat-rich combination diet by Cheng Q1, Zhang X, Wang O, Liu J, Cai S, Wang R, Zhou F, Ji B.(PubMed)
(1757) Comparative evaluation of the antioxidant effects of the natural vitamin C analog 2-O-β-D-glucopyranosyl-L-ascorbic acid isolated from Goji berry fruit by Zhang Z1, Liu X, Zhang X, Liu J, Hao Y, Yang X, Wang Y.(PubMed)
(1758) Qi Zi(Complementary and Alternative Healing University)
(1759) Chinese Herbs – Gou Qi Zi or Qi Zi (Fructus Lycii) by Kyle J. Norton
(1760) A diet formula of Puerariae radix, Lycium barbarum, Crataegus pinnatifida, and Polygonati rhizoma alleviates insulin resistance and hepatic steatosis in CD-1 mice and HepG2 cellsby Liu J1, Zhang H, Ji B, Cai S, Wang R, Zhou F, Yang J, Liu H.(PubMed)
(1761) Dietary Lycium barbarum polysaccharide induces Nrf2/ARE pathway and ameliorates insulin resistance induced by high-fat via activation of PI3K/AKT signaling by Yang Y1, Li W2, Li Y2, Wang Q2, Gao L3, Zhao J4.(PubMed)
(1762) Lycium barbarum (goji) juice improves in vivo antioxidant biomarkers in serum of healthy adults by Amagase H1, Sun B, Borek C.(PubMed)
(1763) Effect of drying methods on physicochemical properties and antioxidant activities of wolfberry (Lycium barbarum) polysaccharide by Zhao Q1, Dong B2, Chen J2, Zhao B3, Wang X1, Wang L1, Zha S4, Wang Y1, Zhang J5, Wang Y5.(PubMed)
(1764) Anti-inflammatory effect of Lycii radicis in LPS-stimulated RAW 264.7 macrophages by Song MY1, Jung HW, Kang SY, Kim KH, Park YK.(PubMed)
(1765) Anti-inflammatory effect of Lycium Fruit water extract in lipopolysaccharide-stimulated RAW 264.7 macrophage cells by Oh YC1, Cho WK, Im GY, Jeong YH, Hwang YH, Liang C, Ma JY.(PubMed)
(1766) Metabolic Signatures of Kidney Yang Deficiency Syndrome and Protective Effects of Two Herbal Extracts in Rats Using GC/TOF by MS. Zhao L1, Wu H, Qiu M, Sun W, Wei R, Zheng X, Yang Y, Xin X, Zou H, Chen T, Liu J, Lu L, Su J, Ma C, Zhao A, Jia W.(PubMed)
(1767) Synaptic plasticity, but not hippocampal neurogenesis, mediated the counteractive effect of wolfberry on depression in rats(1) by Zhang E1, Yau SY, Lau BW, Ma H, Lee TM, Chang RC, So KF.(PubMed)

(1768) A meta-analysis of clinical improvements of general well-being by a standardized Lycium barbarum by Paul Hsu CH1, Nance DM, Amagase H.(PubMed)
(1769) Evaluation of hypoglycemic activity of the polysaccharides extracted from Lycium barbarum by Jing L1, Cui G, Feng Q, Xiao Y.(PubMed)
(1770) Hypoglycemic effects and mechanisms of action of Cortex Lycii Radicis on alloxan-induced diabetic mice by Gao D1, Li Q, Liu Z, Li Y, Liu Z, Fan Y, Li K, Han Z, Li J.(PubMed)
(1771) Protection of retinal ganglion cells and retinal vasculature by Lycium barbarum polysaccharides in a mouse model of acute ocular hypertension by Mi XS1, Feng Q, Lo AC, Chang RC, Lin B, Chung SK, So KF.(PubMed)
(1772) Goji (Lycium barbarum and L. chinense): Phytochemistry, pharmacology and safety in the perspective of traditional uses and recent popularity by Potterat O1.(PubMed)
(1773) Effects of Lycium barbarum polysaccharides on oxidative stress in hyperlipidemic mice following chronic composite psychological stress intervention by Zhu X1, Hu S1, Zhu L1, Ding J1, Zhou Y1, Li G1.(PubMed)
(1774) Hypoglycemic and hypolipidemic effects and antioxidant activity of fruit extracts from Lycium barbarum by Luo Q1, Cai Y, Yan J, Sun M, Corke H..(PubMed)
(1775) Practical Application of Antidiabetic Efficacy of Lycium barbarum Polysaccharide in Patients with Type 2 Diabetes by Cai H, Liu F, Zuo P, Huang G, Song Z, Wang T, Lu H, Guo F, Han C, Sun G1.(PubMed)
(1776) Characterization and hypoglycemic effect of a polysaccharide extracted from the fruit of Lycium barbarum L. by Zhu J1, Liu W, Yu J, Zou S, Wang J, Yao W, Gao X.(PubMed)
(1777) Lycium barbarum polysaccharides reduce intestinal ischemia/reperfusion injuries in rats by Yang X1, Bai H, Cai W, Li J, Zhou Q, Wang Y, Han J, Zhu X, Dong M, Hu D.(PubMed)
(1778) [Effect of Lycium ruthenicum anthocyanins on atherosclerosis in mice]. [Article in Chinese] by Lin L1, Li J, Lv H, Ma Y, Qian Y.(PubMed)