Medical Advisor Journals

Sunday, July 17, 2016

Traditional Chinese Medicine Herbal Therapy - Popular Chinese Herbs - He Huan Pi (Cortex Albizziae Julibrissin)

He Huan Pi (Cortex Albizziae Julibrissin)

He Huan Pi is also known as Albizzia bark. The sweet and neutral herb has been used in TCM as diuretic, tonic agent and to treat mood swing, insomnia, poor memory, relieve pain, etc., as it calms the Mind, resolves depression and stagnation, moves Blood, etc., by enhancing the functions of heart, liver and lung channels.

Ingredients
1. Acetic acid
2. Isovaleraldehyde
3. N-methylene-ethylenediamine
4. 4-penten-2-one
5. Isoamyl alcohol
6. Cis-3-hexen-1-ol
7. N-hexanol
8. Isoamyl acetate
9. 2-methylbutyl acetate
10. Isovaleroxyamine
11. Etc.

Health Benefits
1. Anti cancer
The indentfied of a a new triterpenoidal saponin (1: Julibroside J(21)) with a xylopyranosyl moiety located at its C-21 side chain of Albizia julibrissin hjave showed of inhibitory action against Bel-7402 cancer cell line at 10 microg/ml, according to “A cytotoxic saponin from Albizia julibrissin” by Zou K, Zhao YY, Zhang RY.(1).

2. Anti antitumors
The indentfied of a a new triterpenoidal saponin, julibroside J(28) (1), was isolated from the stem bark of Albizia julibrissin Durazz (Leguminosae) of Albizia julibrissin displayed significant antitumor activity in vitro against PC-3M-1E8, Bel-7402, and HeLa cancer cell lines at 10 microM assayed by SRB method, according to ‘An antitumor compound julibroside J28 from Albizia julibrissin” by Liang H, Tong WY, Zhao YY, Cui JR, Tu GZ.(2).

3. Acute leukemia
In the investigation of antitumor activity of Albizzia julibrissin Durazz (Leguminosae), used as a traditional oriental medicine, the mechanism underlying cytotoxic effect of its extract on human acute leukemia Jurkat T cells found that the cytotoxicity of HaBC18 toward Jurkat T cells is attributable to apoptosis mediated by mitochondria-dependent death-signaling pathway regulated by Bcl-xL, according to “Induction of apoptosis in human acute leukemia Jurkat T cells by Albizzia julibrissin extract is mediated via mitochondria-dependent caspase-3 activation” by Won HJ, Han CH, Kim YH, Kwon HJ, Kim BW, Choi JS, Kim KH.(3)

4. Sedative activity
The isolation of two flavonol glycosides, quercitrin (1) and isoquercitrin (2) of the flowers of Albizzia julibrissin, used as a sedative in oriental traditional medicine, both compounds 1 and 2 increased pentobarbital-induced sleeping time in dose-dependent manner in mice. These results support the use of the flowers of this plant as a sedative agent, according to “Sedative activity of two flavonol glycosides isolated from the flowers of Albizzia julibrissin Durazz” by Kang TH, Jeong SJ, Kim NY, Higuchi R, Kim YC.(4).

5. Arrhythmia
In the isolation of three pyridoxine derivatives from the fresh stem bark of Albizzia julibrissin DURAZZ., found that one of them, named julibrin II, was found to exhibit arrhythmic-inducing action. However, neither the others having the same aglycone nor some glycosides having the same sugar unit showed the action, according to “An arrhythmic-inducing glycoside from Albizzia julibrissin Durazz, IV” by Higuchi H, Kinjo J, Nohara T.(5).

6. Etc.

Side Effects
No side Effect is known

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and restore your health naturally with Chinese diet

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Sources
(1) http://www.ncbi.nlm.nih.gov/pubmed/16880673
(2) http://www.ncbi.nlm.nih.gov/pubmed/16112860
(3) http://www.ncbi.nlm.nih.gov/pubmed/16533581
(4) http://www.ncbi.nlm.nih.gov/pubmed/10904180
(5) http://www.ncbi.nlm.nih.gov/pubmed/1611699

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Women Health: Menstrual Disorder - Dysmenorrhea - Traditional Chinese Herbal Medicine Treatment for Damp-Wind in Dysmenorrhea

Kyle J. Norton(Scholar, Master of Nutrients), all right reserved.
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

Dysmenorrhea

Dysmenorrhea (painful menstruation) is defined as a condition of severe uterine pain during menstruation. Some women may experience periodic pains during or prior to, or after menstrual periods in the lower abdomen as resulting of over production of certain hormones in the prostaglandins family. In traditional Chinese medicine, dysmenorrhea is defined as a pain in the lower abdomen, appearing with menstrual cycle that can spread over to the whole abdomen and lumbosacral region, depending to diagnosis.

Girls in South East Asia have learnt in their early women life from grand mother wisdom, that they do not engage in any activity that distorts their regular period. Menstruation disorders should be treated immediately, otherwise, it may cause wide range of women diseases, such as infertility, according to traditional Chinese medicine. In this article, we will discuss dysmenorrhea - causes of heat pattern in TCM perspective.

Treatment for Damp-Wind in Dysmenorrhea

Damp wind is considered as a condition of excessive fluids accumulated in the body organs and tissues after prolong eating of cool and cold foods or/and engaging in activity that requires to present in the damp cool environment. Under extremed condition, it causes rebellion qi attacking the lower part of the body, including reproductive organ and joints. The belows are some Chinese damp wind tonic herbs.
1. Wei Ling Xian
Wei long xian is also known as clematis recta, it is one of the herb used to strengthen the clematis meridian by expelling the wind-damp due to blockage of the channel caused by prolong period of fluid accumulated in women lower part of the body, thus relieving menstrual cramps and pain

2. Qin Jiao
Qin Jiao is also known as Chinese bitter root or macrophylla root. It is used to strengthen the meridian gallbladder-liver-stomach, by improving the stomach is food digestion and smoothing the qi absorbed by the spleen, thus decreasing the rebellion qi flow of lung and liver causes of menstrual disorder such as menstrual cramps and pain.

3. Du Huo
Du huo also is known as European angelica and garden angelica, it is warm in nature and has been used to smooth the qi flow of kidney-bladder meridian by strengthening and smoothing the kidney qi flow. It also improves the function of kidney in fluid distribution and blood flow to the reproductive organ, thereby lessening the risk of development of damp wind that disturbs the lower part of the women body.

4. Mu Gua
Mu gua is also known as cydonia oblongata, it improves the function of the meridian liver-Spleen, thereby smoothing the qi flow to spleen and liver and liver function in blood formation, resulting in reducing the dis-harmonization of stomach and spleen in food absorption, leading to dampness accumulation and blood stagnation causes of damp wind.

5. Fang Ji
Fang ji is also known as stephania root, it has been used in tradition in treating meridian bladder-spleen-kidney blockage. By smoothing the qi flow of spleen and kidney and increasing the bladder in assisting secretion of urine, the herb decreases the risk of dampness accumulation of fluids in the lower part of the body. It is said that fang qi also helps to expel the wind from the body, thus reducing the damp wind causes of abdominal distention.
Pregnancy Miracle
Reverse Infertility And Get Pregnant Naturally
Using Holistic Ancient Chinese Medicine

Chinese Food Therapy
The Best Way to prevent, treat your disease, including Obesity
and restore your health naturally with Chinese diet

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Super foods Library, Eat Yourself Healthy With The Best of the Best Nature Has to Offer

The Obesity' Research and Studies of Family support and weight-loss

General Health: Appendicitis: Treatment in Traditional Chinese medicine perspective

Herbal therapy: Popular Herbal Muira Puama (Ptychopetalum)

Kyle J. Norton(Scholar and Master of Nutrients, all right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

Herbal Muira Puama (Ptychopetalum)

Muira Puama is a flowering plants in the genus of Ptychopetalum in thefamily Olacaceae, native to the Amazon rainforest.The herb has been used in traditional medicine to enhance sexual desire, erectile function and to treat dysentery, rheumatism nervous tension, depression, etc.

Health benefits
1. Sex drive
In the assessment of he efficacy of a unique herbal formulation of Muira puamaand Ginkgo biloba (Herbal vX) in the treatment of sexual dysfunction in healthy women, found thatStatistically significant improvements occurred in frequency ofsexual desires, sexual intercourse, and sexual fantasies, as well as in satisfaction with sex life, intensity of sexual desires, excitement of fantasies, ability to reach orgasm, and intensity of orgasm. Reported compliance and tolerability were good. These initial findings support the strong anecdotal evidence for the benefits of Herbal vX on the female sex drive, according to "Effects of Herbal vX on libido and sexual activity in premenopausal and postmenopausal women" byWaynberg J, Brewer S.(1)

2. Neurodegenerative conditions
In the identification of a standardized ethanol extract from Ptychopetalum olacoides (POEE), a medicinal plant favored by the elderly in Amazon communities and its inhibition in brain areas relevant to cognition found that this study provides definitive proof of meaningful anticholinesterase activity compatible with the observed promnesic and anti-amnesic effects of POEE in mice, reaffirming the potential of this extract for treating neurodegenerative conditions where a hypofunctioning cholinergic neurotransmission is prominent, according to "Acetylcholinesterase inhibition in cognition-relevant brain areas of mice treated with a nootropic Amazonian herbal (Marapuama)" by Figueiró M, Ilha J, Pochmann D, Porciúncula LO, Xavier LL, Achaval M, Nunes DS, Elisabetsky E.(2)

3. Anti-stress effects
In the investigation of Marapuama (Ptychopetalum olacoides Bentham, PO and its anti-stress properties found that Ptychopetalum olacoides (Marapuama) might possess adaptogen-like properties, according to "Anti-stress effects of the "tonic"Ptychopetalum olacoides (Marapuama) in mice" by Piato AL, Detanico BC, Linck VM, Herrmann AP, Nunes DS, Elisabetsky E.(3)

4. Antioxidant activities
In the identification of of PO ethanol extract (POEE) free-radical scavenging properties in vitro, found that POEE administration reduced free-radical production in the hypothalamus, lead to significant decrease in lipid peroxidation in the cerebral cortex, striatum and hypothalamus, as well as in the carbonyl content in cerebellum and striatum. In terms of antioxidant enzymes, catalase activity was increased in the cortex, striatum, cerebellum and hippocampus, while glutathione peroxidase activity was increased in the hippocampus and concluded that POEE contains compounds able to improve the cellular antioxidant network efficacy in the brain, ultimately reducing the damage caused by oxidative stress, according to "Antioxidant activities of Ptychopetalum olacoides ("muirapuama") in mice brain" by Siqueira IR, Fochesatto C, Torres IL, da Silva AL, Nunes DS, Elisabetsky E, Netto CA.(4)

5. Anxiogenic properties
In the assessment of Alcohol infusions of roots of Ptychopetalum olacoides Benth. (PO), known as Marapuama or Muirapuama, used in the Brazilian Amazon as a 'nerve tonic' found that
found that P. olacoides ethanol extract (30, 100 and 300 mg/kg) decreased exploratory behaviour in the hole-board test, without interfering with locomotion or motor coordination (rota-rod test), according to "Anxiogenic properties of Ptychopetalum olacoides Benth. (Marapuama)" by da Silva AL, Bardini S, Nunes DS, Elisabetsky E.(5)

6. Antidepression effect
In the investigation of standardized PO ethanol extract (POEE) on the forced swimming (FST) and tail suspension tests (TST) and theirs antidepression effect found that Consistent with traditional use, the results indicate that POEE possesses antidepressant-like effects, possibly mediated by beta-adrenergic and D(1) dopamine receptors, according to "Antidepressant profile of Ptychopetalum olacoides Bentham (Marapuama) in mice" by Piato AL, Rizon LP, Martins BS, Nunes DS, Elisabetsky E.(6)

7. Etc.

Side effects
1. Overdoses may cause nervous tension, including insomnia and restlessness
2. Do not use the herb in Children, or if you are pregnant or breast feeding without approval from the related field specialist
3. Do not use the herb combination with other sexual stimulants.
4. Etc.

Chinese Food Therapy
The Best Way to prevent, treat your disease, including Obesity
and restore your health naturally with Chinese diet

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Super foods Library, Eat Yourself Healthy With The Best of the Best Nature Has to Offer

Sources
(1) http://www.ncbi.nlm.nih.gov/pubmed/11186145
(2) http://www.ncbi.nlm.nih.gov/pubmed/20833520
(3) http://www.ncbi.nlm.nih.gov/pubmed/19682881
(4) http://www.ncbi.nlm.nih.gov/pubmed/17433649
(5) http://www.ncbi.nlm.nih.gov/pubmed/12164265
(6) http://www.ncbi.nlm.nih.gov/pubmed/19067380

Phytochemicals in Foods - The Effects of Cinnamic acid

Kyle J. Norton(Scholar and Master of Nutrients, all right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

Cinnamic acid

Cinnamic acid is a phytochemical in the class of Hydroxycinnamic acids, found abundantly in cinnamon, aloe. etc.

Health Benefits
1. Depigmenting activity
In the examination of the effects of cinnamic acid on melanin biosynthesis within the melanocytes and brown guinea pigs, found that cinnamic acid exhibited depigmenting activity on the UV-B-induced hyperpigmentation of brown guinea pig skin. Our results suggest that cinnamic acid might act as a skin whitening agent via inhibition of tyrosinase activity and expression within melanocytes, according to "Inhibitory effects of cinnamic acid on melanin biosynthesis in skin" by Kong YH, Jo YO, Cho CW, Son D, Park S, Rho J, Choi SY.(1)

2. Gastroprotective Effect
in the sudy of the ulcer-preventive properties of aqueous extract of ginger rhizome (GRAE) belonging to the family Zingiberceae, found that compositional analysis favored by determination of the efficacy of individual phenolic acids towards their potential ulcer-preventive ability revealed that between cinnamic (50%) and gallic (46%) phenolic acids, cinnamic acid appear to contribute to better H(+), K(+)-ATPase and Helicobacter pylori inhibitory activity, while gallic acid contributes significantly to anti-oxidant activity, according to "Gastroprotective Effect of Ginger Rhizome (Zingiber officinale) Extract: Role of Gallic Acid andCinnamic Acid in H+, K+-ATPase/H. pylori Inhibition and Anti-oxidative Mechanism" by Nanjundaiah SM, Annaiah HN, M Dharmesh S.(2)

3. Antioxidant effects
found that TPP-OH protected cells against H(2)O(2) and linoleic acid hydroperoxide-induced oxidative stress. As mitochondrial oxidative damage is associated with a number of clinical disorders, TPP-OH may be a useful lead that could be added to the family of mitochondria-targeted antioxidants that can decrease mitochondrial oxidative damage, according to "Rational discovery and development of a mitochondria-targeted antioxidant based on cinnamic acidscaffold" by Teixeira J, Soares P, Benfeito S, Gaspar A, Garrido J, Murphy MP, Borges F.(3)

4. Prostate cancer
In the study, testing the effects of tetra-bromo-cinnamic acid (TBCA) as an effort to develop new chemotherapy for prostate cancers, found that TBCA blocked AR nuclear translocation and gene expression. To confirm the target specificity, we used gene-specific siRNAs for both CK2α and CK2α' subunits, and the results suggested that both CK2 catalytic subunits are involved in androgen-stimulated AR nuclear translocation and AR-mediated gene expression in prostate cancer cells, according to "Casein kinase 2 inhibition attenuates androgen receptor function and cell proliferation in prostate cancer cells" by Yao K, Youn H, Gao X, Huang B, Zhou F, Li B, Han H.(4)

5. Antimicrobial activity
In a series of cinnamic acid derivatives synthesized and then brominated with bromine in the presence of chloroform or acetic acid, found that the tested compounds had mainly antifungal activity and were moderately active against Gram-positive bacteria. Bromination of the double bond determined the enhancement of the antimicrobial activity for all the tested compounds, according to "[Antimicrobial activity of some cinnamic acid derivatives].[Article in Romanian]" by Jităreanu A, Tătărîngă G, Zbancioc AM, Tuchiluş C, Stănescu U.(5)

6. Insulin secretion
in the elucidation of the mechanisms by which p-Methoxycinnamic acid (p-MCA), acinnamic acid increases [Ca2+]i and insulin secretion in INS-1 cells. p-MCA (100 μM) increased [Ca2+]i in INS-1 cells, found that p-MCA enhanced glucose-, glibenclamide-induced insulin secretion whereas it also potentiated the increase in insulin secretion induced by arginine, and Bay K 8644, an L-type Ca2+ channel agonist. Taken together, our results suggest that p-MCA stimulated insulin secretion from pancreatic β-cells by increasing Ca2+ influx via the L-type Ca2+ channels, but not through the closure of ATP-sensitive K+ channels, according to "Mechanisms of p-methoxycinnamic acid-induced increase in insulin secretion" by
Adisakwattana S, Hsu WH, Yibchok-anun S.(6)

7. Lung cancer
In the development of a practicable method previously to transform and obtain pure c-CA, and the pure compound was used to evaluate the anti-invasive effect on human adenocarcinoma A549 cells, found that the invasive ability was significantly (p<0.05) reduced to 68% and 65%, respectively, relative to PMA treatment alone after treatment of PMA-treated A549 cells with either 50 μM c-CA or 100 μM t-CA for 24 h. The results suggest that both of the c-CA and t-CA are inhibitors for invasion of A549 cells and the activity of c-CA seems to be higher than t-CA, according to "A comparative study on the effectiveness of cis- and trans-form of cinnamic acid treatments for inhibiting invasive activity of human lung adenocarcinoma cells" by Yen GC, Chen YL, Sun FM, Chiang YL, Lu SH, Weng CJ.(7)

8. Anti-platelet aggregation
A series of novel ligustrazinyloxy-cinnamic acid derivatives were synthesized and evaluated for their inhibitory effect on adenosine diphosphate (ADP)-induced platelet aggregation in vitro,
found that compound 2e displayed the highest protective effect on the proliferation of the damaged ECV-304 cells (EC(50) = 0.020 mM), and compound 2f was the most active anti-platelet aggregation agent (EC(50) = 0.054 mM). Structure-activity relationships were briefly discussed, according to "Ligustrazine derivatives. Part 5: design, synthesis and biological evaluation of novel ligustrazinyloxy-cinnamic acid derivatives as potent cardiovascular agents" by Chen H, Li G, Zhan P, Liu X.(8)

9. Hypoglycemic effects
In the study of the effect of cinnamic acid, ferulic acid, p-coumaric acid, eugenol, chlorogenic acid, and caffeic acid, alone and in combination with two commercial oral hypoglycemic drugs (OHD), namely, thiazolidinedione (THZ) and metformin, on the uptake of 2-deoxyglucose (2DG) by 3T3-L1 adipocytes, found that Chlorogenic and cinnamic acids increased the expression of PPARγ, whereas other hydroxycinnamic acids enhanced the expression of PI3K, indicating different mechanisms of action between these compounds. These phytochemicals were able to reduce the expressions of the fatty acid synthase and HMG CoA reductase genes, indicating that they may be able to reduce the secondary complications caused by the accumulation of lipids, according to "Interaction of cinnamic acidderivatives with commercial hypoglycemic drugs on 2-deoxyglucose uptake in 3T3-L1 adipocytes' by Prabhakar PK, Doble M.(9)

10. Anti malarial activity
In the assessment, in vitro of antimalarial activity of four compounds isolated from Kigelia africana stem bark (atranorin - KAE1, specicoside - KAE7, 2β,3β,19α-trihydroxy-urs-12-20-en-28-oic acid - KAE3, and p-hydroxy-cinnamic acid - KAE10) and their drug interactions among themselves and their combination effects with quinine and artemetherinvestigation of the antiplasmodial activity and drug interactions against the multidrug-resistant W2mef strain of Plasmodium falciparum using the parasite lactate dehydrogenase assay, found that all the three compounds showed synergistic effects with artemether, unlike the slight antagonistic interactions of atranorin and 2β,3β,19α-trihydroxy-urs-12-en-28-oic acid in combination with quinine. K. africana compounds are therefore likely to serve as leads in the development of new partner drugs in artemether-based combination therapy, according to "Antimalarial drug interactions of compounds isolated from Kigelia africana (Bignoniaceae) and their synergism with artemether, against the multidrug-resistant W2mef Plasmodium falciparum strain" by Zofou D, Tene M, Tane P, Titanji VP.(10)

11. Etc.