Medical Advisor Journals

Sunday, August 7, 2016

Food Therapy: Fruits - Prunes(Prunus domestica)

Prune is a dried plum, therefore it is a genus of Prunus with many species, belong to family Rosaceae with unknown origin. Plum is cultivated for commercial drying called dried plum or prune. Prune is a sticky chewy texture and very nutritious.

Nutrients
1. Carbohydrates
2. Fiber
3. Vitamin A
4. Vitamin B3
5. Vitamin B6
6. Vitamin C
7. Vitamin E
8. Copper
9. Iron
10. Magnesium
11.Manganese
13. Phosphorus
14. Potassium
15. Etc.

Health Benefits
A. Health benefits according to studies
1. Liver diseases
In the research of prunes (Prunus domestica) and its effect on liver function, found that There was significant reduction of serum alanine transaminase (p 0.048) and serum alkaline phosphatase (p 0.017) by the lower dose of prunes. There was no change in serum aspartate transaminase and bilirubin. Alteration in liver function by use of prunes may have clinical relevance in appropriate cases and prunes might prove beneficial in hepatic disease, according to "Report: prunes and liver function: a clinical trial" by Ahmed T, Sadia H, Khalid A, Batool S, Janjua A.(a)

2. Hypertension
In the investigation of prunes (Prunus domestica) and its effect on blood pressure found that there was significant reduction of blood pressure by single dose of prunes daily group and the controls (p < 0.05). With the double dose of prunes, only systolic BP was reduced significantly (p < 0.05), according to "Use of prunes as a control of hypertension" by Ahmed T, Sadia H, Batool S, Janjua A, Shuja F.(b)

3. Antioxidants
In the evaluation of Nine different beverages, including prune juice and their free radical scavenging activity found that there was an almost 7-fold difference in the Total Oxyradical Scavenging Capacity (TOSC) between brewed coffee and ascorbic acid. The data suggest a potential role for commonly consumed beverages in lowering the risk of pathophysiologies associated with peroxyl radical-mediated events, according to "Comparison of peroxyl radical scavenging capacity of commonly consumed beverages" by Kwon do Y, Choi KH, Kim SJ, Choi DW, Kim YS, Kim YC.(c)

4. Cognitive effects
In the observation of prune juice and normal aging in animals and humans is accompanied by a decline in cognitive performance indicated that rats that drank plum juice from 19 to 21 mo of age had improved working memory in the Morris water maze, whereas rats fed dried plum powder were not different from the control group, possibly due to the smaller quantity of phenolics consumed in the powder group compared with the juice group. These results are discussed in relation to the amount and type of phenolics present in the plum products and in relation to other dietary intervention studies in which cognitive benefits have been reported, according "Plum juice, but not dried plum powder, is effective in mitigating cognitive deficits in aged rats" by Shukitt-Hale B, Kalt W, Carey AN, Vinqvist-Tymchuk M, McDonald J, Joseph JA.(d)

5. Human colon carcinoma Caco-2
In the study of the dried fruits of certain cultivars of Prunus domestica L. extract and its effect Caco-2, KATO II found that PE treatment for 24 h led to apoptotic changes in Caco-2 such as cell shrinkage and blebbed surfaces due to the convolutions of nuclear and plasma membranes and chromatin condensation and induced apoptosis in Caco-2, acording to "Prune extract (Prunus domestica L.) suppresses the proliferation and induces the apoptosis of human colon carcinoma Caco-2" by Fujii T, Ikami T, Xu JW, Ikeda K.(e)

6. Hypercholesterolemia
In the identification of Forty-one free-living adult men with mild hypercholesterolemia (5.2-7.5 mmol/L) voluntarily participated in an 8-wk crossover study designed to determine the effect of prunes as a source of fiber on plasma cholesterol and on fecal output and bile acid concentration found that During theprune period, subjects supplemented their usual diets with 12 prunes (100 g; 6 g dietary fiber) daily. Plasma low-density-lipoprotein cholesterol was significantly lower after the prune period (3.9 mmol/L) than after the grape-juice-control period (4.1 mmol/L). Fecal bile acid concentration of lithocholic acid was significantly lower after the prune period (0.95 mg bile acid/g dry wt stool) than after the grape-juice-control period (1.20 mg bile acid/g dry wt stool), according to "Consumption of prunes as a source of dietary fiber in men with mild hypercholesterolemia" by Tinker LF, Schneeman BO, Davis PA, Gallaher DD, Waggoner CR.(f)

7. Etc.

B. Health Benefits according to concentration
1. Protein
Protein in Prune is not only beneficial to the cardiovascular diseases, according to the study of "Soy protein, isoflavones, and cardiovascular health: an American Heart Association Science Advisory for professionals from the Nutrition Committee" by Sacks FM, Lichtenstein A, Van Horn L, Harris W, Kris-Etherton P, Winston M; American Heart Association Nutrition Committee(I), but also plays an important role in treating diabetes, according to "Effects of soy protein and isoflavones on glycemic control and insulin sensitivity: a 6-mo double-blind, randomized, placebo-controlled trial in postmenopausal Chinese women with prediabetes or untreated early diabetes" by Liu ZM, Chen YM, Ho SC, Ho YP, Woo J.(II)

2. Vitamin A
Vitamin A is not only important in preventing types I diabetes, according to "A close relationship between type 1 diabetes and vitamin A-deficiency and matrix metalloproteinase and hyaluronidase activities in skin tissues" byTakahashi N, Takasu S.(III) but also may be associated with compromised bone health, according to "Vitamins and bone health: beyond calcium and vitamin D" by Ahmadieh H, Arabi A.(IV)

3. Vitamin C
a. Asthma
Vitamin C is one of the key antioxidant vitamins which is abundant in the extracellular fluid lining the lung and low vitamin C intake has been associated with pulmonary dysfunction, such as asthma, according to the study of "Vitamin Csupplementation for asthma" by Kaur B, Rowe BH, Arnold E.(V)

b. DNA Damage
Ascorbic acid (AA), known as vitamin C, has important antioxidant vitamin has exerted the activity in preventing (imazalil)IMA-induced cause of DNA damage, according to the stuyd of "The protective role of ascorbic acid on imazalil-induced genetic damage assessed by the cytogenetic tests' by Türkez H, Aydin E.(VI)

4. Phosphorus
Phosphorus is one of essential trace minerals to maintains healthy teeth and bones, according to the study of "Phosphorus nutrition and the treatment ofosteoporosis" by Heaney RP, posted in PubMed (VII).

5. Potassium
Beside is a important minerals for lymphatic function in regulating the body fluids, it is also essential in preventing the forming of kidney stone, according to the study of "Empiric use of potassium citrate reduces kidney-stone incidence with the ketogenic diet" by McNally MA, Pyzik PL, Rubenstein JE, Hamdy RF, Kossoff EH., posted in PubMed(http://www.ncbi.nlm.nih.gov/pubmed/19596731), researchers wrote in conclusion that Oral potassium citrate is an effective preventive supplement against kidney stones in children who receive the KD, achieving its goal of urine alkalinization. Universal supplementation is warranted.

6. Etc.

C. Other health benefits
1. Immune system
Since prune contains high amount antioxidants, it enhances the immune system in fighting against the forming of free radical thus reducing the risk of irregular cell growth, inflammation and infection, according to the study of "[Antioxidant and/or free radical scavenger vitamins in tropical medicine].[Article in French]" by Clerc M., posted in PubMed(1)

2. Antioxidants and cardivascular health
Antioxidant also deceases the risk of heart diseases and strike by guarding our body against cholesterol oxidation and breaking off of capillaries and hardening of arterial walls, according to the study of "Vasoactive and antioxidant activities of plants used in Mexican traditional medicine for the treatment of cardiovascular diseases" by Ibarra-Alvarado C, Rojas A, Mendoza S, Bah M, Gutiérrez DM, Hernández-Sandoval L, Martínez M., Posted in PubMed(2). For more information of Antioxidant and Cancers and Diseases, visit http://the-anti-aging-guide.blogspot.com/2011/03/anti-aging-guide.html

3. Potassium
Potassium in prune helps to maintain normal blood pressure by making blood vessels less sensitive to substances, such as hormones, causing blood vessel to contract, thus causing hypertension of that can lead to cardiovascular diseases, according to the study of "Blood pressure lowering efficacy of potassium-sparing diuretics (that block the epithelial sodium channel) for primary hypertension" by Heran BS, Chen JM, Wang JJ, Wright JM., posted in PubMed(3)

4. Fibers
High amount of fibers helps to regulate blood sugar by releasing glucose slowly into bloodstream thus reducing pancreas stress cause of insulin sensitive, according to the study of "Long-term dietary treatment with increased amounts of fiber-rich low-glycemic index natural foods improves blood glucose control and reduces the number of hypoglycemic events in type 1 diabetic patients" by Giacco R, Parillo M, Rivellese AA, Lasorella G, Giacco A, D'Episcopo L, Riccardi G., posted in PubMed(4)

5. Cells nourishment
Prune contains high amount of iron, the mineral that enhances the reproduction of red blood cells and formation of hemoglobin, thus increasing the the oxygen absorption from the lung to nourish the body' cells, according to the study of "Iron deficiency in women: assessment, causes and consequences" by Coad J, Conlon C., posted in PubMed(5)

6. Etc.

Side Effects
As plum, it may cause problem for people with untreated kidney and gallbladder diseases and reduce the absorption of calcium.

Chinese Food Therapy
The Best Way to prevent, treat your disease, including Obesity
and restore your health naturally with Chinese diet

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Super foods Library, Eat Yourself Healthy With The Best of the Best Nature Has to Offer

Sources
(a) http://www.ncbi.nlm.nih.gov/pubmed/20884464
(b) http://www.ncbi.nlm.nih.gov/pubmed/21409897
(c) http://www.ncbi.nlm.nih.gov/pubmed/19280160
(d) http://www.ncbi.nlm.nih.gov/pubmed/19097856
(e) http://www.ncbi.nlm.nih.gov/pubmed/17190111
(f) http://www.ncbi.nlm.nih.gov/pubmed/1850578

(I) http://www.ncbi.nlm.nih.gov/pubmed/16418439
(II) http://www.ncbi.nlm.nih.gov/pubmed/20335543
(III) http://www.ncbi.nlm.nih.gov/pubmed/19160185
(IV) http://www.ncbi.nlm.nih.gov/pubmed/21967159
(V) http://www.ncbi.nlm.nih.gov/pubmed/19160185
(VI) http://www.ncbi.nlm.nih.gov/pubmed/21986888
(VII) http://www.ncbi.nlm.nih.gov/pubmed/14708952

(1) http://www.ncbi.nlm.nih.gov/pubmed/1303294

(2) http://www.ncbi.nlm.nih.gov/pubmed/20645769
(3) http://www.ncbi.nlm.nih.gov/pubmed/20091662
(4) http://www.ncbi.nlm.nih.gov/pubmed/11023137
(5) http://www.ncbi.nlm.nih.gov/pubmed/21934611

General Health: Cirrhosis - The Causes

Most cases of Cirrhosis are caused by excessive and chronic alcohol drink and hepatitis.
1. Excessive and chronic alcohol drink
Prolonged period of excessive alcohol drink can lead to onset of the disease. In the study to provide a quantitative assessment of the association between alcoholintake and risk of liver cirrhosis, by the Centre for Addiction and Mental Health, showed that alcohol consumption had a significantly larger impact on mortality ofliver cirrhosis compared with morbidity. Also, the same amount of average consumption was related to a higher risk of liver cirrhosis in women than in men.(1).

2. Hepatitis
a. Heptitis C
Hepatitis C virus (HCV) infects more than 170 million people worldwide, and thereby becomes a series global health challenge. Chronic infection with HCV is considered one of the major causes of end-stage liver disease including cirrhosisand hepatocellular carcinoma(2).

b. Hepatitis B
Following development of liver cirrhosis in patients with chronic hepatitis B, liverdisease may continue to progress and decompensation or hepatocellular carcinoma (HCC) may occur(3).

3. Biliary cirrhosis
a. Primary Biliary cirrhosis
Primary Biliary cirrhosis is defined as a chronic liver diseases as a result of the slow destruction of the bile duct of the liver. According to the study by, Nagasaki University Graduate School of Biomedical Sciences, patients with primary biliarycirrhosis (PBC) exhibit a variety of clinical manifestations and patterns of disease progression. The genetic variants of CYP7A1 and its transcriptional activators (HNF4A and PPARGC1A) may activate bile acid synthesis, resulting in the accumulation of bile acids in hepatocytes and eventually leading to the predisposition to PBC progression(4). Other study in the examined single nucleotide polymorphisms (SNPs) in cytotoxic T-lymphocyte antigen 4 (CTLA4) and solute carrier family 4 anion exchanger, member 2 (SLC4A2), which have been associated with the pathogenesis of PBC in Caucasian patients, found that CTLA4 and SLC4A2 genetic polymorphisms are differentially associated with PBC development and progression, as well as anti-gp210 or anti-centromere antibody production, in Japanese PBC patients(5).

b. Secondary Biliary cirrhosis
Secondary Biliary cirrhosis is defined as a condition of the blocking of the bile duct of the liver as a result infection or iatrogenic bile duct injury (BDI), bile duct strictures, gallstones, sclerosing, etc.
Secondary biliary cirrhosis was the indication for liver transplantation (LT) in 5 (1.7%) out of 300 LTs performed in our center between Feb 2002 and April 2011, according to the Surgery and Liver Transplantation, M. Curie Hospital, Szczecin(6).

4. Other causes (non-B, non-C liver cirrhosis (NBNC LC))
In a nationwide survey of NBNC LC in Japan at the 15th General Meeting of the Japan Society of Hepatology, 6999 NBNC LC with patients were registered at 48 medical institutions. Epidemiological and clinical factors, indicated that The percentage of NBNC LC among LC patients was 26%. NBNC LC patients were categorized into 11 types according to etiological agents: non-alcoholic steatohepatitis (NASH), 14.5%; alcoholic liver disease (ALD), 55.1%; fatty liverdisease (FLD), except NASH, ALD, and other known etiology, 2.5%; primarybiliary cirrhosis, 8.0%; other biliary cirrhosis, 0.8%; autoimmune hepatitis, 6.8%; metabolic disease, 0.6%; congestive disease, 0.8%; parasitic disease, 0.2%; other known etiology, 0.2%; and unknown etiology, 10.5%(7).

Chinese Food Therapy
The Best Way to prevent, treat your disease, including Obesity
and restore your health naturally with Chinese diet

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Super foods Library, Eat Yourself Healthy With The Best of the Best Nature Has to Offer

Sources
Sources
(a) http://www.cdc.gov/nchs/fastats/liverdis.htm
(1) http://www.ncbi.nlm.nih.gov/pubmed/20636661
(2) http://www.ncbi.nlm.nih.gov/pubmed/23355912
(3) http://www.ncbi.nlm.nih.gov/pubmed/22504333
(4) http://www.ncbi.nlm.nih.gov/pubmed/23354620
(5) http://www.ncbi.nlm.nih.gov/pubmed/21594562
(6) http://www.ncbi.nlm.nih.gov/pubmed/22743721
(7) http://www.ncbi.nlm.nih.gov/pubmed/23347437

The Obesity' Research and Studies of Beverage intake among preschool children and its effect on weight status

Kyle J. Norton(Scholar, Master of Nutrients), all right reserved.
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

Obesity is a medical condition of excess body fat accumulated overtime, while overweight is a condition of excess body weight relatively to the height. According to the Body Mass Index(BMI), a BMI between 25 to 29.9 is considered over weight, while a BMI of over 30 is an indication of obesity. According to the statistic, 68% of American population are either overweight or obese.

You can calculate your BMI index BMI= weight (kg)/ height (m2)

The Studies of Beverage intake among preschool children and its effect on weight status

In the study to evaluate the beverage intake among preschool children who participated in the National Health and Nutrition Examination Survey 1999-2002 and investigate associations between types and amounts of beverages consumed and weight status in preschool-aged children. Dr. O'Connor TM, and the research team at Baylor College of Medicine showed that On average, preschool children drank less milk than the 2005 Dietary Guidelines for Americans recommendation of 16 oz/day. Only 8.6% drank low-fat or skim milk, as recommended for children who are older than 2 years. On average, preschool children drank < 6 oz/day 100% fruit juice. Increased beverage consumption was associated with an increase in the total energy intake of the children but not with their BMI. Prospectively studying preschool children beyond 2 to 5 years of age, through their adiposity rebound (approximately 5.5-6 years) to determine whether there is a trajectory increase in their BMI, may help to clarify the role of beverage consumption in total energy intake and weight status(1).

Chinese Food Therapy
The Best Way to prevent, treat your disease, including Obesity
and restore your health naturally with Chinese diet

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Super foods Library, Eat Yourself Healthy With The Best of the Best Nature Has to Offer

(1) "Beverage intake among preschool children and its effect on weight status" by O'Connor TM, Yang SJ, Nicklas TA.

Women Health: The Obesity and Infertility Research and Studies of Improving reproductive performance in overweight/obese women

Kyle J. Norton(Scholar, Master of Nutrients), all right reserved.
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

Obesity is a medical condition of excess body fat accumulated overtime, while overweight is a condition of excess body weight relatively to the height. According to the Body Mass Index(BMI), a BMI between 25 to 29.9 is considered over weight, while a BMI of over 30 is an indication of obesity. According to the statistic, 68% of American population are either overweight or obese.

You can calculate your BMI index BMI= weight (kg)/ height (m2)

The Studies of Improving reproductive performance in overweight/obese women

There is a very high prevalence of obese women in the infertile population and many studies have highlighted the link between obesity and infertility. According to the study by the The Queen Elizabeth Hospital, posted in PubMed, found that a large proportion of infertile women have polycystic ovary syndrome (PCOS) which is also linked with increased risk of obesity and other metabolic anomalies. The association between obesity and/or PCOS and hyperinsulinaemia, hyper androgenism and abnormal secretion of other hormones, such as leptin, underlies many reproductive disorders observed in this population. It has been demonstrated that weight loss can improve the fertility of obese women through the recovery of spontaneous ovulation, whereas others will have improved response to ovarian stimulation in infertility treatment.

Pregnancy Miracle
Reverse Infertility And Get Pregnant Naturally
Using Holistic Ancient Chinese Medicine

Chinese Food Therapy

The Best Way to prevent, treat your disease, including Obesity

and restore your health naturally with Chinese diet

Ovarian Cysts And PCOS Elimination

Holistic System In Existence That Will Show You How To

Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Super foods Library, Eat Yourself Healthy With The Best of the Best Nature Has to Offer

Men Health: Benign prostatic hyperplasia(BPH) - The Effect of Vitamin D

Benign prostatic hyperplasia(BPH)

Benign prostatic hyperplasia(BPH) is defined as a condition of increased in the number of cells of prostate gland, causing partial, or sometimes virtually complete obstruction of the urinary tract. According to statistic, BPH commonly starts at age of 30 and symptoms usually can not be realized until age of 50. More than half of men between age of 60-70 are experience symptoms of BPH and only 10% are required treatment. Suggestion of BPH is associated to nutritional status and eating habits, according to the study, 30 male patients with clinically confirmed and treated disease of the prostatic gland, including 15 men (aged 51-75 years) with BPH and 15 men (aged 51-73 years) with PC, indicated improper nutritional status lead of incorrect nutritional habits which fail to improve their health status, may be the cause of the development of some diet-dependent diseases, such as BPH and prostate cancer(a). A proper diet with vegetable, fruit containing zinc may reduce the risk of the disease from starting(b)(c).

Epidemiological studies, indicated intake of vegetables and fruits accompanied with healthy life style may be associated in prevented risk and treatment of enlarged prostate(d)(e)(f), it may due to enhancement of antioxidants effect on over production of prostate cells(g)(h).

The Effect of Vitamin D

Vitamin D is a fat-soluble secosteroids found in small amount in few foods, including salmon, mackerel, sardines and tuna. The vitamin plays an important role in modulation of cellular proliferation, apoptosis induction, tumor growth suppression and promotion in absorption of minerals, including calcium, iron, magnesium, phosphate and zinc.
Epidemiological studies, focusing the use of dietary vitamin E in reduced risk of benign prostatic hyperplasia(BPH) have produced inconsistent results(a)(b).
1. Vitamin D receptor(VDR) and BPH
The study of 222 prostate cancer patients, 209 benign prostatic hyperplasia (BPH) patients, 128 male controls who were over 60 years old and without any evidence of prostate cancer or BPH, and 198 female controls in Japanese men to exp;ore the genetic mutation of polymorphism in the VDR gene for risk of prostate cancer and BPH found the positive effect of BsmI polymorphism in the VDR gene in protection against prostate cancer(1). Other study showed rs731236(genetic)variant of the vitamin D receptor had a protective effect for LUTS, a common symptoms of men with BPH(2), and VDR Fok I polymorphisms(morphs of the phenotype) may be correlated with BPH complicated by histological prostatitis, the study of Graduate School, South Medical Universit showed(3). In Indian population, Taq-I(a restriction enzyme isolated from the bacterium Thermus aquaticus in 1978) and Bsm-I genetic variants of VDR gene influence susceptibilityBPH(4). But in the study of polymorphims with functional significance in the Bsm, Apa 1 and Taq 1 genes were therefore compared in 28 prostate cancer (CaP), 44 benign prostate hyperplasia (BPH) and 30 control cases in Thailand, indicated no significant variation in distribution of these three groups. Of that suggested these variations in the distribution frequencies from country to country and depending to other factors such as sun exposure, dietary and other lifestyle factors(5).

2. The serum of Vitamin D
Some researchers suggested that serum of vitamin D may be an indication of early onset of benign prostatichyoerplasia BPH. According to the study by American Urological Association Education and Research, low levels of 25-OHvitamin D is associated with benign prostatic hyperplasia(6). But a study byDemocritus University of Thrace showed no clear relationship between vitamin Dand serum levels of PSA or-of f/t-PSA(free/total prostate specific antigen) in PD patients(7).

3. The effects
BPH(1). BXL-628. a vitamin D3 analog, showed to decrease prostate growth and BPH symptoms, through inhibition of cell migration and cytoskeleton(a cellular scaffolding or skeleton contained within a cell's cytoplasm) remodeling in altered bladder contractility associated with BPH-induced lower urinary tract symptoms(8). Elocalcitol, a vitamin D3 analog, reduced the static component of BPH by inhibiting the activity of intraprostatic growth factors downstream of the androgen receptor, by targeting the RhoA(regulation and timing of cell division)/ROCK(protein, RhoA, RhoC, and ROCK expression were related to poor tumor differentiation) and NF-kappaB(involved in cellular responses to stimuli such as stress, cytokines, free radicals, ultraviolet irradiation, oxidized LDL, and bacterial or viral antigens.) pathway(9). The New York University School of Medicine study showed increase intake of vitamin D impact an adverse correlation with decreased BPH prevalence(10). Another novel nonsecosteroidal VDR agonist (CH5036249) showed an cell growth inhibitory activity of CH5036249 to be comparable to that of 1alpha,25(OH)2D3(11). Other analogs, including BXL-353, may also be potential for patients with BPH(12).

Taken altogether, serum of vitamin D may not be realizable diagnosis in determination the early onset of BPH, and vitamin D analogs are associated to reduced risk and treatment of Benign prostatic hyperplasia(BPH). As a;ways. all articles written by Kyle J. Norton are for information & education only, please consult your Doctor & Related field specialist before applying.

Chinese Food Therapy
The Best Way to prevent, treat your disease,
particular in treatment of Reproductive Men Health

Super foods Library, Eat Yourself Healthy With The Best of the Best Nature Has to Offer

References
(a) Dietary patterns, supplement use, and the risk of symptomatic benign prostatic hyperplasia: results from the prostate cancer prevention trial by Kristal AR1, Arnold KB, Schenk JM, Neuhouser ML, Goodman P, Penson DF, Thompson IM.(PubMed)
(b) Dietary patterns, supplement use, and the risk of benign prostatic hyperplasia by Poon KS1, McVary KT.(PubMed)
(c) Vitamin D and benign prostatic hyperplasia -- a review by Espinosa G1, Esposito R, Kazzazi A, Djavan B.(PubMed)
(1) Association of vitamin D receptor gene polymorphism with prostate cancer andbenign prostatic hyperplasia in a Japanese population by Habuchi T1, Suzuki T, Sasaki R, Wang L, Sato K, Satoh S, Akao T, Tsuchiya N, Shimoda N, Wada Y, Koizumi A, Chihara J, Ogawa O, Kato T.(PubMed)
(2) Systematic Review and Meta-analysis of Candidate Gene Association Studies of Lower Urinary Tract Symptoms in Men by Cartwright R1, Mangera A2, Tikkinen KA3, Rajan P4, Pesonen J5, Kirby AC6, Thiagamoorthy G7, Ambrose C8, Gonzalez-Maffe J9, Bennett PR10, Palmer T11, Walley A12, Järvelin MR13, Khullar V14, Chapple C15(PubMed)
(3) [Relationship between vitamin D receptor gene Fok I polymorphisms and benign prostatic hyperplasia complicated by histological prostatitis].[Article in Chinese] by Ruan L1, Zhong WD, Li ZM, Hua X.(PubMed)
(4) Association of genetic variants of the vitamin D receptor (VDR) gene (Fok-I, Taq-I and Bsm-I) with susceptibility of benign prostatic hyperplasia in a North Indian population by Manchanda PK1, Konwar R, Nayak VL, Singh V, Bid HK.(PubMed)
(5) Lack of association of VDR polymorphisms with Thai prostate cancer as compared with benign prostate hyperplasia and controls by Chaimuangraj S1, Thammachoti R, Ongphiphadhanakul B, Thammavit W.(PubMed)
(6) Low 25-OH vitamin D is associated with benign prostatic hyperplasia by Haghsheno MA1, Mellström D, Behre CJ, Damber JE, Johansson H, Karlsson M, Lorentzon M, Peeker R, Barret-Connor E, Waern E, Sundh V, Ohlsson C, Hammarsten J.(PubMed)
(7) Serum levels of prostate-specific antigen and vitamin D in peritoneal dialysis patients by Passadakis P1, Ersoy F, Tam P, Memmos D, Siamopoulos K, Ozener C, Akçiçek F, Camsari T, Ates K, Ataman R, Vlachojannis J, Dombros N, Utas C, Akpolat T, Bozfakioglu S, Wu GG, Karayaylali I, Arinsoy T, Stathakis C, Yavuz M, Tsakiris D, Dimitriades A, Yilmaz ME, Gültekin M, Karayalçin B, Challa A, Polat N, Oreopoulos DG.(PubMed)

(8 BXL-628, a vitamin D receptor agonist effective in benign prostatic hyperplasiatreatment, prevents RhoA activation and inhibits RhoA/Rho kinase signaling in rat and human bladder by Morelli A1, Vignozzi L, Filippi S, Vannelli GB, Ambrosini S, Mancina R, Crescioli C, Donati S, Fibbi B, Colli E, Adorini L, Maggi M.(PubMed)
(9) Vitamin D receptor agonists target static, dynamic, and inflammatory components of benign prostatic hyperplasia by Adorini L1, Penna G, Fibbi B, Maggi M.(PubMed)
(10) Vitamin D and benign prostatic hyperplasia -- a review by Espinosa G1, Esposito R, Kazzazi A, Djavan B.(PubMed)
(11) A novel nonsecosteroidal VDR agonist (CH5036249) exhibits efficacy in a spontaneous benign prostatic hyperplasia beagle model by Taniguchi K1, Katagiri K, Kashiwagi H, Harada S, Sugimoto Y, Shimizu Y, Arakawa H, Ito T, Yamazaki M, Watanabe T, Kato A, Hoshino E, Takahashi T, Esaki T, Suzuki M, Takeda S, Ichikawa F, Harada A, Sekiguchi N, Ishigai M, Kawata H, Yoneya T, Onuma E, Sudoh M, Aoki Y.(PubMed)
(12) Inhibition of spontaneous and androgen-induced prostate growth by a nonhypercalcemic calcitriol analog by Crescioli C1, Ferruzzi P, Caporali A, Mancina R, Comerci A, Muratori M, Scaltriti M, Vannelli GB, Smiroldo S, Mariani R, Villari D, Bettuzzi S, Serio M, Adorini L, Maggi M.(PubMed)

Women Health: Premenstrual syndrome(PMS): The Adverse effects of Caffeine

Premenstrual syndrome(PMS)

Premenstrual syndrome is defined as faulty function of the ovaries related to the women's menstrual cycle, effected over 70% to 90% of women in the US and lesser for women in Southeast Asia because of difference in living style and social structure. The syndrome also interferes women's physical and emotional states, and daily activities as a result of hormone fluctuation and occurs one to two weeks before menstruation and then declines when the period starts.

The Adverse effects of Caffeine

1. Vitamins and minerals deficiency
Food containing caffeine also contains tannin(1) which block the digestive system in absorbing of vitamins and minerals in the digestive tract(1)t including iron, zinc, copper(2), magnesium(3), etc., the vital vitamins and minerals for women with PMS.

2. Unbalance of blood sugar
Caffeine is a stimulant, it helps to improve the function of nervous system(4) if it is taken in a right dose. Over dose of caffeine causes suddenly surge and fall of blood sugar(5) in the blood stream resulting in over production of adrenaline hormone(6)(7) leading to symptoms of PMS(8).

3. Methylxathines
Methylxathines in food containing caffeine inhibits the actions of sleepiness induces adenosine(11) and treat symptoms of asthma(12)(13), but may exhibit side effects of breast tenderness(9), begnin lumps(9)(10) and breast pain(10).

4. Theophylline and theobromine
Foods containing caffeine also contains methylxathines and theobromine which contrite to relaxed muscle(14) and improved blood pressure, if they are taken in small dose. Over dose of methylxathines and theobromine may increase the risk of blood sugar unbalance(15) leading to over production adrenaline hormone(16) causes of PMS symptoms(8).

5. Addictive
Caffeine is so additive(17),. It narrows your blood vessels(18) when taken. complete stop suddenly may induce symptoms of greater sleepiness, lower mental alertness, and poorer performance on simple reaction time, choice reaction time and recognition memory tasks, etc.(19). It is wise to stop it slowly over a period of time.

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particular in treatment of menstrual disorder in Women Health

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Holistic System In Existence That Will Show You How To
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References
(1) Assessment of Anti-nutritive Activity of Tannins in Tea By-products Based on In vitro Rumen Fermentation by Kondo M1, Hirano Y2, Ikai N3, Kita K4, Jayanegara A5, Yokota HO3.(PubMed)
(2) [Factors which modify the nutritional state of iron: tannin content of herbal teas].[Article in Spanish] by Pizarro F1, Olivares M, Hertrampf E, Walter T.(PubMed)
(3) Rhubarb tannins extract inhibits the expression of aquaporins 2 and 3 inmagnesium sulphate-induced diarrhoea model by Liu C1, Zheng Y2, Xu W2, Wang H2, Lin N1.(PubMed)
(4) Caffeine and the central nervous system: mechanisms of action, biochemical, metabolic and psychostimulant effects by Nehlig A1, Daval JL, Debry G.(PubMed)
(4) [Comparison of caffeine citrate and aminophylline for treating primary apnea in premature infants].[Article in Chinese] by Xu JL1, Wang RQ, Chen DM.(PubMed)
(5) Caffeine's impairment of insulin-mediated glucose disposal cannot be solely attributed to adrenaline in humans by Battram DS1, Graham TE, Dela F.(PubMed)
(6) Adrenaline rush: the role of adrenergic receptors in stimulant-induced behaviors by Schmidt KT1, Weinshenker D.(PubMed)
(7) [Correlation between neurotransmitters and neurosteroids and premenstrual syndrome patients of Gan-yang ascending syndrome and Gan-qi stagnation syndrome].[Article in Chinese] by Gao H1, Xia T, Qiao MQ.(PubMed)
(8) Adrenaline rush: the role of adrenergic receptors in stimulant-induced behaviors by Schmidt KT1, Weinshenker D.(PubMed)
(9) Methylxanthines and benign breast disease by Schairer C, Brinton LA, Hoover RN.(PubMed)
(10) Caffeine restriction as initial treatment for breast pain by Russell LC.(PubMed)
(11) Effect of caffeine on intravenous adenosine-induced hyperemia in fractional flow reserve measurement by Matsumoto H1, Nakatsuma K, Shimada T, Ushimaru S, Mikuri M, Yamazaki T, Matsuda T.(PubMed)
(12) [Asthma bronchiale: lung function is affected by coffeine].[Article in German] by Dinh QT1, Bals R.(PubMed)
(13) Can we find better bronchodilators to relieve asthma symptoms? by Townsend EA1, Yim PD, Gallos G, Emala CW.(PubMed)
(14) Opposite actions of caffeine and creatine on muscle relaxation time in humans by Hespel P1, Op't Eijnde B, Van Leemputte M.(PubMed)
(15) Differential effects of methylxanthines on local cerebral blood flow andglucose utilization in the conscious rat by Grome JJ, Stefanovich V.(PubMed)
(16) Mood, alertness and sympathetic-adrenal medullary activity during the menstrual cycle by Pátkai P, Johannson G, Post B.(PubMed)
(17) The buzz: is caffeine addiction real?[No authors listed](PubMed)
(18) Effects of chronic administration of ethanolic extract of kolanut (Cola nitida) and caffeine on vascular function by Salahdeen HM, Omoaghe AO, Isehunwa GO, Murtala BA, Alada AR.(PubMed)
(19) Faster but not smarter: effects of caffeine and caffeine withdrawal on alertness and performance by Rogers PJ1, Heatherley SV, Mullings EL, Smith JE.(PubMed)

Overcome Infertility - Diagnosis of Infertility From Letter A - Z in Male

Kyle J. Norton(Scholar and Master of Nutrients, all right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

Diagnosis of Infertility From Letter A - Z

Infertility is defined as inability of a couple to conceive after 12 months of unprotected sexual intercourse or can not carry the pregnancy to full term. It effects over 5 millions couple alone in the U. S. and many times more in the world, because of unawareness of treatments, only 10% seeks help from professional specialist. In fact, More than 40% of infertility of a couple is caused by male inability to fertilize. Diagnosis is a analytics approach, after initial consultation and medical history and personal information have been taken from a patient or couple. The main objective conventional diagnosis is to find the causes of infertility, but unfortunately, it has less than 1% successful rate. We will try to give you the definitions of type of diagnosis in alphabet order.

Before reading the definition of types of diagnosis, you may want to know briefly what important information will be record on your personal file
I. General medical history
1. Any miscarriage, previous pregnancies and abortion.
2. Any ectopic pregnancy
3. Any previous surgery
4. Have you now on HRT.
5. Use of conceptive method, type of use
6. Any reproductive chronic pain including STD. urinary tract infection ad chronic diseases.
7. Medication you are taking now
8. Any medication of your mother during pregnancy to rule out infertility caused by birth defect
9. Your lifestyle.

II. Physical Exam in male patients
a) Testicle related including injure, childhood testicle illness and abnormal in birth
b) Age of puberty
c) Number of previous sexual partners
d) Question related to ejaculation and impotence
e) Do you have child with other women
f) Have you ever contacted and treated with sexual transmitted diseases
g) Hot bath and sunnas
h) Smoking and drugs abuse
i) Expose to radiation
j) workplace hazard
k) Medication may influence your sexual organs.
l) Other general exam depending to your specialist (herbalist or others).

III. Diagnosis or test From Conventional Perspective from letter A to Z in Male patient
1. Acrosome reaction test
After the sample is taken your fertility specialist exam the acrosome reaction of your sperms to see how your sperm penetrate the female egg, how the enzymes (acrosome then acrosin released from the sperm head ) in sperm work through tough coating of the eggs and fgertilized it. The purpose of this test is to diagnosis the sperm acrosome then acrosin to see hoe these enzyme help to break tough surface of the egg. If not it may be the cause of infertility and specific treatment is required. It happens only 5% of infertility male population.
2. Antisperm antibody
An antisperm antibody test as defined as a test to look for abnormal function of immune system antibodies that fight against a male's sperm in blood, vaginal fluids, or semen. With a substance added to the sample sperm, the test will tell whether the sperm is affected by proteins of the immune system or not.

3. Biochemical analysis
The study of the chemical substances and vital processes occurring in male testicle such as the concentration of white blood cells, the level of fructose in the semen, and the volume, pH, and liquefaction time of the ejaculate.

4. Computer-Assist semen analysis
The sample of sperm is scanned in to the computer pre store program to show how the sperm quality, quantity, shape and movement. Since any small change of the computer may produce a significant change in sperm calculation, therefore any abnormal sperm count should be confirmed by manual count.

5. Hemizona assay
Hemizona assay is the analysis to compare sample sperm of the male to the sperm of the fertiliized male by splitting the marure and normal egg into 2 half. 1/2 is tested by sample sperm and the other half is tested by fertilitized male sperm.

6. Hormone evaluation
Hormonal evaluation is a study to measure the levels of certain hormones produced by your body such as levels of FSH and testosterone which are inlvoved directly in sperm production. The test will only be used is the semen of sperm anaalusis come back with low density of sperm or your specialist suspects that hormone imbalance is the cause of infertility.

7. Human zona pellucida binding test
The testes help to exam how the sperm bind to outer layer of the egg. including hemizona assay.

8. Hypoosmotic swelling test (HOST)
hypoosmotic swelling test (HOST) is the test used to identify sperm membrane for structure integrity by examining how the sperm tails react to special sugar and salt. Only healthy sperm can react in that circumstance.

9. Pene trak
Pene trak is the test for 90 minutes to check the movement of sperm through a normal and friendly mucus in the test tube.

10. Peroxidase staining
It is a test to check for infection by differentiating white blood cell from the immature sperm.

11.Post-coital/cervical mucus test
It is a test to see how friendly the mucus of the cervix toward the sperm invasion during ovulation. The result can be determined after
a) Male partner sperm with female partner cervical mucus
b) Male partner sperm with healthy mucus
c) Known healthy sperm with female partner mucus
d) Known healthy sperm with known healthy muscle

12. Sperm penetration assay (hamster test)
Sperm penetration test only is needed if the normal semen test can not determine the sperm penetration ability then hamster eggs with the ouster membrane has been stripped off are used in place of female eggs because of it's structural similarity to human eggs. After the sperm and hamster eggs have incubated for three hours, the eggs are checked for sperm penetration. Any percentage over 10 % is considered normal and potential for fertilization. Since is uses eggs than human being, good sperm penetration rate in hamster test does not guarantee 100% of positive result in human.

13.Sperm-Ubiquitin tag immunoassay (SUTI)
Sperm-Ubiquitin tag immunoassay ignores other sperm attributes and focusing solely on sperm's ubiquitin because ubiquitin is considered as a universal marker of any sperm abnormalities including sperm damage and sperm defective, thereby reducing some unecessary treatments.

14. Semen analysis
A semen analysis is usually the first test for all infertility male , it helps to measure the amount of semen a man produces and determines the quantity and quality of sperm such as size, shape. movement and PH level in the sample.
a) Normal form sperm
Ovary head, single tail with intact midsection and an uncoiled.
b) Abnormal heads
Head of sperm if too big or too small and other than ovary head.
c) Abnormal tails
Coil, broken, bent tail and other than single tail.
d) Immature gen cells
Since white blood cells and white gen cells have a very similar apprance and structure, it is up to the specialist to make sure that the present is immature gen cells and not white blood cells.
e) Vital staining
It is the analysis to see the percentage of dead sperm compare to lice one.
f) Urinalysis
It is to make sure the infertility is not caused by retrograde rejaculation and the urinary tract is not infected.

15. Scrotal sonography
Scotal sonography is used to evaluate the testicle disorder and surrouding organs including prostate gland, epididymis, an absent or undescended testicle and any testicle abnormality.

16.Testicle biopsy
A small is taken and tested for the ability of sperm producing cell to produce normal cells. This test is necessary if the infertility male is found to have no sperm in semen, normal sex levels of hormone and abnormal sperm with unknown cause. The risk of the test may cause testicle damage.

17. Vasography
Vasography is a Radiographic study of the vas deferens. It helps to determine if the vas deferens is blocked or not and the reason of such blockage. In this study, if there is large amount of sperm containing fluid presented when the vas deferens is open, it indicate there is a block appeared in the vesicle end of the vas deferens. If there is no fluid presented, the procedure continue until the cause of blockage is found, if there is one.

Pregnancy Miracle
Reverse Infertility And Get Pregnant Naturally
Using Holistic Ancient Chinese Medicine

Chinese Food Therapy

The Best Way to prevent, treat your disease, including Obesity

and restore your health naturally with Chinese diet

Ovarian Cysts And PCOS Elimination

Holistic System In Existence That Will Show You How To

Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Super foods Library, Eat Yourself Healthy With The Best of the Best Nature Has to Offer