Medical Advisor Journals

Friday, September 9, 2016

Phytochemicals in Foods- The Effects of Carvacrol

Chinese Food Therapy
The Best Way to prevent, treat your disease, including Obesity
and restore your health naturally with Chinese diet

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Super foods Library, Eat Yourself Healthy With The Best of the Best Nature Has to Offer

Herbal therapy: Popular Herbal Triphala

Kyle J. Norton(Scholar and Master of Nutrients, all right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

Triphala

Triphala is an Ayurvedic fomula consisting of equal parts of Amalaki (Emblica officinalis), Bibhitaki (Terminalia bellirica), and Haritaki (Terminalia chebula) ofmyrobalans. The herb has been used in traditional medicine to treat constipation, tonify colon, gastrointestinal tract, balance digestive system, cholesterol, enhance circulation, uterine health, etc.

Health Benefits
1. Antibacterial efficacy
In the assessment ofthe antibacterial efficacy of triphala against salivary mutans streptococci in comparison with the 'gold standard' chlorhexidine, found that The antimicrobial action of triphala against mutans streptococci closely parallels that of chlorhexidine. It does not have the side effects commonly associated with chlorhexidine and is cost effective, according to "Assessment of antibacterial efficacy of triphala against mutans streptococci - a randomised control trial" by Srinagesh J, Pushpanjali K.(1)

2. Prostate cancer
In the identification of gallic acid (GA), a major bioactive cytotoxic constituent of a polyherbal Ayurvedic formulation - triphala (TPL) and its effect on (AR)(+) LNCaP prostate cancer and normal epithelial cells, found that TPL contains 40% unidentified polyphenolic acids, of which 2.4% comprised GA. GA induced severe morphological alterations and was about 3-fold more cytotoxic towards cancer cells than TPL. This activity increased further in the presence of dihydrotestosterone. GA toxicity on normal cells was low at 72 h. Combination of GA with flutamide caused higher toxicity to cancer cells than either of the compounds alone, according to "Differential cytotoxicity of triphala and its phenolic constituent gallic acid on human prostate cancer LNCap and normal cells" by Russell LH Jr, Mazzio E, Badisa RB, Zhu ZP, Agharahimi M, Millington DJ, Goodman CB.(2)

3. Dental health
In the study of the effects of a mouthwash prepared with Triphala on dental plaque, gingival inflammation, and microbial growth and compare it with commercially available Chlorhexidine mouthwash, found that in the inhibitory effect on microbial counts except Lactobacillus where Triphala had shown better results than Chlorhexidine. It was concluded that there was no significant difference between the Triphala and the Chlorhexidine mouthwash, according to "The effect ofTriphala and Chlorhexidine mouthwash on dental plaque, gingival inflammation, and microbial growth" by Bajaj N, Tandon S.(3)

4. Anticataract effects
In the evaluation of evaluation of riphala (TP) is composed of Emblica officinalis, Terminalia chebula, and Terminalia belerica anticataract potential in vitro and in vivo in a selenite-induced experimental model of cataract, found that in vivo TF 25mg/kg developed only 20% nuclear cataract as compared to 100% in control. TP prevents or retards experimental selenite-induced cataract. This effect may be due to antioxidant activity. Further studies are warranted to explore its role in human cataract, according to "Evaluation of anticataract potential of Triphala in selenite-induced cataract: In vitro and in vivo studies" by Gupta SK, Kalaiselvan V, Srivastava S, Agrawal SS, Saxena R.(4)

5. Antibacterial, wound healing, and antioxidant activities in would healing
In the indentification of the Triphala extract (10% w/w) in vivo on wound healing on infected rat model by rate of healing, bacterial count, biochemical analysis, and expression of matrix metalloproteinases, found that results showed the antibacterial, wound healing, and antioxidant activities of Triphala ointment, necessary for the management of infected wounds. Active principles of theTriphala may be further evaluated and used as an excellent therapeutic formulation for infected wounds, according to "Triphala promotes healing of infected full-thickness dermal wound" by Kumar MS, Kirubanandan S, Sripriya R, Sehgal PK.(5)

6. Cancers prevention and treatment
In the review of Triphala, an antioxidant-rich herbal formulation and its effects as colon cleanser, digestive, diuretic, and laxative, indicated that Experimental studies in the past decade have shown that Triphala is useful in the prevention of cancer and that it also possesses antineoplastic, radioprotective and chemoprotective effects, according to "Triphala, Ayurvedic formulation for treating and preventing cancer: a review" by Baliga MS.(6)

7. Antioxidants
In the assessment of The aqueous extract of the fruits of Emblica officinalis (T1), Terminalia chebula (T2) and Terminalia belerica (T3) and their equiproportional mixture triphala for their in vitro antioxidant activity, indicated that the extracts were found to possess the ability to scavenge free radicals such as DPPH and superoxide. As the phenolic compounds present in these extracts are mostly responsible for their radical scavenging activity, the total phenolic contents present in these extracts were determined and expressed in terms of gallic acid equivalents and were found to vary from 33% to 44%, according to "In vitro antioxidant studies and free radical reactions of triphala, an ayurvedic formulation and its constituents" by Naik GH, Priyadarsini KI, Bhagirathi RG, Mishra B, Mishra KP, Banavalikar MM, Mohan H.(7)

8. Anti-ulcer activity
In the study of the efficacy of the polyherbal formulation NR-ANX-C (composed of the extracts from Withania somnifera, Camellia sinensis, Ocimum sanctum, shilajith and triphala) and its antioxidant potential in terms of protection from lipid peroxidation and the antiulcer activity, found that R-ANX-C (25 and 50 mg/kg) was more efficacious than ranitidine in reducing ulcer index in both the models. At the highest dose tested (50 mg/kg), NR-ANX-C was comparable to omeprazole in preventing ulcer formation in the pyloric ligature model. NR-ANX-C showed a dose- dependent decrease in gastric juice volume and total acidity in both the models. A dose-dependent increase in gastric pH and total adherent gastric mucus was also seen in NR-ANX-C treated groups. The extent of lipid peroxidation was also reduced in the test drug treated groups, according to "Evaluation of the anti-ulcer activity of NR-ANX-C (a polyherbal formulation) in aspirin & pyloric ligature induced gastric ulcers in albino rats" by Nair V, Arjuman A, Gopalakrishna HN, Dorababu P, Mirshad PV, Bhargavan D, Chatterji D.(8)

9. Hypolipidemic activity
In the investigation of Hypolipidemic activity of haritaki (terminalia chebula) in atherogenic diet induced hyperlipidemic rat, found that Haritaki was found to possess significant hypolipidemic activity. The results also suggest that Haritaki at 1.05 and 2.10 mg/kg b.wt. concentrations are an excellent lipid-lowering agent, according to "Hypolipidemic activity of haritaki (terminalia chebula) in atherogenic diet induced hyperlipidemic rats" by Maruthappan V, Shree KS.(9)

10. Anti-Salmonella activity
In the research of Fruits of T. belerica extract with petroleum ether, chloroform, acetone, alcohol and water and its effect gainst Salmonella typhi and Salmonella typhimurium , found that that aqueous extract of T. belerica was bactericidal at high concentrations where as low concentrations showed bacteriostatic property. In vitro cellular toxicity studies showed no cyto-toxicity associated with T. belerica extracts. Pretreatment of mice with aqueous extract of T. belerica conferred protection against experimental Salmonellosis and 100% survival of animals has been reported when challenged with lethal doses of S. typhimurium, according to "Anti-Salmonella activity of Terminalia belerica: in vitro and in vivo studies" by

Madani A, Jain SK.(10)

11. Anti bacteria infection
In the study of the effect of phytochemical (phenolic, flavonoid and carotenoid) and antibacterial activities of aqueous and ethanol extracts of Triphala and its individual components (Terminalia chebula, Terminalia belerica and Emblica officinalis) against certain bacterial isolates (Pseudomonas aeruginosa, Klebsiella pneumoniae, Shigella sonnei, S. flexneri, Staphylococcus aureus, Vibrio cholerae, Salmonella paratyphi-B, Escherichia coli, Enterococcus faecalis, Salmonella typhi) obtained from HIV infected patients, found that most of the bacterial isolates were inhibited by the ethanol and aqueous extracts of T. chebula followed by T. belerica and E. officinalis by both disk diffusion and MIC methods, according to "Evaluation of the growth inhibitory activities of Triphala against common bacterial isolates from HIV infected patients" by Srikumar R, Parthasarathy NJ, Shankar EM, Manikandan S, Vijayakumar R, Thangaraj R, Vijayananth K, Sheeladevi R, Rao UA.(11)

12. Pancreatic tumor
In the elucidation of the molecular mechanism of Triphala against human pancreatic cancer in the cellular and in vivo model, found that Triphala is effective in inhibiting the growth of human pancreatic cancer cells in both cellular and in vivo model. Our data also suggests that the growth inhibitory effects of Triphala is mediated by the activation of ERK and p53 and shows potential for the treatment and/or prevention of human pancreatic cancer, according to "Triphala inhibits both in vitro and in vivo xenograft growth of pancreatic tumor cells by inducing apoptosis" by Shi Y, Sahu RP, Srivastava SK.(12)

13. Gouty arthritis
In the investigation of the anti-arthritic effect of Triphala in the paw volume, lysosomal enzyme activities, lipid peroxidation, anti-oxidant status and inflammatory mediator TNF-alpha in control and monosodium urate crystal-induced mice, found that Triphala treatment (1 gm/kg/b.w. orally) significantly inhibited the paw volume and the levels of lysosomal enzymes, lipid peroxidation and inflammatory mediator tumour necrosis factor-alpha; however the anti-oxidant status was found to be increased in plasma, liver and spleen of monosodium urate crystal-induced mice when compared to control mice. In addition, beta-glucuronidase and lactate dehydrogenase level were reduced in Triphala (100 microg/ml) treated monosodium urate crystal-incubated polymorphonuclear leucocytes. In conclusion, the results obtained clearly indicated that Triphalaexerted a strong anti-inflammatory effect against gouty arthritis, according to "An in vivo and in vitro potential of Indian ayurvedic herbal formulation Triphalaon experimental gouty arthritis in mice" by Sabina EP, Rasool M.(13)

14. Etc.

Side effects
1. Overdoses can cause gastrointestinal discomfort, such as dehydration cause of diarrhea
2. Do not take the herb in children, or if you are pregnant or breast feeding without approval from the related field specialist.
3. Overdose may cause colon damage.
4. Etc.

Pregnancy Miracle
Reverse Infertility And Get Pregnant Naturally
Using Holistic Ancient Chinese Medicine

Chinese Medicine Herbal Therapy - Popular Chinese Herbs - Mu Bie Zi (Momordica cochinchinensis (Lour.) Spreng)

Kyle J. Norton(Scholar, Master of Nutrients), all right reserved.
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

Mu Bie Zi (Momordica cochinchinensis (Lour.) Spreng)

Mu Bie Zi is also known as Indian trumpet flower seed. The bitter, slightly sweet, warm and toxic herb has been used in TCM to treat bunacles, scofula, pain in rheumatism, spastic muscles, etc., as it enhances the functions of liver, spleen and stomach channels.

Ingredients
1. Momordic acid
2. Gypsogenin
3. Oleanolic acid
4. α-elaeostearic acid
5. Amino acid
6. Phytosterol
7. Etc.

Health Benefits
1. Immunological effect
The immunological effect of an extract from Momordica cochinchinensis seed (ECMS) on immune responses against infectious bursal disease (IBD) in chickens was evaluated showed that A significant increase in mitogenic stimulated lymphocyte proliferation was also recorded in all ECMS groups as compared with controls (P<0.05; P<0.01). No adverse effect of ECMS was noted on growth performance, although average weight gain was significantly higher in 20 microg (7, 14, 21, 28, and 35 d) and 40 or 80 microg (14 d) of ECMS groups as compared with controls (P<0.05; P<0.01)(1).

2. Newcastle disease (ND)
The study evaluated the immunological effect of extract of Momordica cochinchinensis (Lour.) Spreng. seeds (ECMS) on the immune response against Newcastle disease (ND) in chickens. F showed that Humoral and cellular immune responses were evaluated by indirect ELISA assay and the 3-(4,5-dimethyl thiazol-2-yl)-2,5-diphenyl tetrazolium bromide method. Results indicated that humoral immune response was enhanced by ECMS 14 d postimmunization. Eighty micrograms of ECMS was the best dose with the ND vaccine and was significantly different from the other groups 21 d after immunization. No significant differences were found in the cellular immune response, whereas the 80 microg of ECMS group had higher values than the other groups 35 d after immunization(2).

3. Etc.

Side Effects
1. Do not use in case of weakness
2. Do not use the herb in newborn, children, or if you are pregnant or breast feeding without first consulting with related field specialist
3. Etc.

Pregnancy Miracle
Reverse Infertility And Get Pregnant Naturally
Using Holistic Ancient Chinese Medicine

Chinese Food Therapy

The Best Way to prevent, treat your disease, including Obesity

and restore your health naturally with Chinese diet

Ovarian Cysts And PCOS Elimination

Holistic System In Existence That Will Show You How To

Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Super foods Library, Eat Yourself Healthy With The Best of the Best Nature Has to Offer

Sources
(1) http://www.ncbi.nlm.nih.gov/pubmed/20460658

Overcome Infertility: Cervical Mucus test of Female Infertility In Conventional medicine Perspective

Infertility is defined as inability of a couple to conceive after 12 months of unprotected sexual intercourse. It effects over 5 millions couple alone in the U. S. and many times more in the world. Because of unawareness of treatments, only 10% seeks help from professional specialist.

Cervical Mucus test of Female Infertility In Conventional medicine Perspective

Cervical mucus test is the study of the cervical mucus through out menstrual cycles. The main focus of the test is to analyze "Is the mucus is friendly to sperm invasion or not ?". There are 2 types of cervical test.

Procedure
1. Spinnbarkeit
The sample is taken from the vagina to check for the day of ovulation.
2. Postcoital test
The test is examined within 4 hours at the doctor office or laboratory after sexual intercourse and assuming that the male partner has a healthy sperm production.

Diagnosis
a) Spinnbarkeit test
Spinnbarkeit is a self help kit, it can be done by a woman at comfort at her own home to exam the mucus characteristics, because the mucus consistently change throughout menstrual cycle. If the mucus is watery and stretchable, it means it is very close or a good chance that the ovulation is coming.
b) Postcoital test
It is also known as sperm-sperm mucus interaction test or Sims-Huhner test, it is done after the Spinnbartkeit test or at the laboratory just before ovulation to see how the sperm of the male partner swim through the watery and stretchable mucus. If the sperm is able to swim normally then the cervical mucus is consider friendly to sperm invasion or otherwise. If there are no sperm are found in the cervical mucus but presented in vagina, or sperm are found clumping, no movement or dead then the female partner may be suspected to produce sperm hostile cervical mucus. More analysis may be required to rule out any external factors.

Pregnancy Miracle
Reverse Infertility And Get Pregnant Naturally
Using Holistic Ancient Chinese Medicine

Chinese Food Therapy

The Best Way to prevent, treat your disease, including Obesity

and restore your health naturally with Chinese diet

Ovarian Cysts And PCOS Elimination

Holistic System In Existence That Will Show You How To

Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Super foods Library, Eat Yourself Healthy With The Best of the Best Nature Has to Offer

Women Health: Menstrual Disorders - Oligomenorrhea Prevention: How to prevent in common sense approaches

The Prevention

A. How to prevent in common sense approaches
1. Reduce stress by meditation or yoga
Meditation and yoga can help to keep breathing slow and controlled and to relax and energized the body, thus reducing the stress.

2. Avoid intensive exercise
Intensive exercise can reduce estrogen levels, which can lead irregular menstrual cycle including Oligomenorrhea

3. Nutrient deficiency
unhealthy diet can cause deficiency of vitamins and minerals, including vitamin B complex and magnesium , leading to Oligomenorrhea.

4. Weight loss
Weight loss too quickly increases the risk of hormonal imbalance that can lead to Oligomenorrhea

5. Moderate drinking
According to the answer to the question of Does alcohol affect menstruation?, Chosen by AskerAppolnia_76 stated that YES it does... in a couple of different ways.First, it inhibits the secretion of the ADH, or anti-diuretic hormone from the pituitary gland in the brain... that's why we pee so much when we drink. You are essentially getting dehydrated, so the blood thickens and your menstrual flow will slow down until you re-hydrate yourself. Second, when you drink hard core, like lots of hard liquor or go on a bender for a few days, you can have extra periods or have skipped or late periods too. the reason for this is it messes up your metabolism and your hormones.

6. Etc.
Chinese Food Therapy
The Best Way to prevent, treat your disease,
particular in treatment of menstrual disorder in Women Health

Pregnancy Miracle
Reverse Infertility And Get Pregnant Naturally
Using Holistic Ancient Chinese Medicine

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Super foods Library, Eat Yourself Healthy With The Best of the Best Nature Has to Offer

Phytochemicals for Treatment of Myeloma (Multiple Myenoma)

Phytochemials are defined as a group of chemical compound found naturally in plants, including fruits, vegetables, beans, grains, etc. Many studies have proven that they can because of certain phytochemicals, but for what ever reason, there are either no clinical trials follow through or the studies can not make to stage of clinical trials. Do not expect the pharmateutical or foods industrial companies to pay for the researches, as the discovery of the phytochemicals to cure cancers can only dampen the profits of both industries as phytochemicals can not be patented.

Cancer is a class of diseases in which a group of cells growing and multiplying disordered and uncontrollable way in our body, have become progressively worse and damaged other healthy tissues, sometimes spreads to other organs in the body via lymph or blood and results may be in death.
Food intake can help to prevent and treat cancers.

Myeloma (Multiple Myenoma)

Multiple myeloma (Myeloma) is a type of cancer originated from plasma cells in the bone marrow. It is a type of white blood cell normally responsible for the production of antibodies to protect our body against infection with some characteristics.

Types of food to prevent and treat Multiple myeloma (Myeloma)
1. Turmeric
In the study of Curcumin (diferuloylmethane) down-regulates the constitutive activation of nuclear factor-kappa B and IkappaBalpha kinase in human multiple myeloma cells, leading to suppression of proliferation and induction of apoptosis, scientists at the The University of Texas MD Anderson Cancer Center, showed that Curcumin suppressed the constitutive IkappaBalpha phosphorylation through the inhibition of IKK activity. Curcumin also down-regulated the expression of NF-kappaB-regulated gene products, including IkappaBalpha, Bcl-2, Bcl-x(L), cyclin D1, and interleukin-6. This led to the suppression of proliferation and arrest of cells at the G(1)/S phase of the cell cycle. Suppression of NF-kappaB complex by IKKgamma/NF-kappaB essential modulator-binding domain peptide also suppressed the proliferation of MM cells. Curcumin also activated caspase-7 and caspase-9 and induced polyadenosine-5'-diphosphate-ribose polymerase (PARP) cleavage. Curcumin-induced down-regulation of NF-kappaB, a factor that has been implicated in chemoresistance, also induced chemosensitivity to vincristine and melphalan(1).

2. Green tea
(-)-epigallocatechin-3-gallate extracted from green tea have exerted the inhibitory effect against multiple myeloma cells. Dr. Shammas MA and the research team at Veterans Administration Boston Health Care System, and Dana Farber Cancer Institute/Harvard Medical School, showed that EGCG interacts with the 67-kDa laminin receptor 1 (LR1), which is significantly elevated in myeloma cell lines and patient samples relative to normal PBMCs. RNAi-mediated inhibition of LR1 resulted in abrogation of EGCG-induced apoptosis in myeloma cells, indicating that LR1 plays an important role in mediating EGCG activity in MM while sparing PBMCs. Evaluation of changes in gene expression profile indicates that EGCG treatment activates distinct pathways of growth arrest and apoptosis in MM cells by inducing the expression of death-associated protein kinase 2, the initiators and mediators of death receptor-dependent apoptosis (Fas ligand, Fas, and caspase 4), p53-like proteins (p73, p63), positive regulators of apoptosis and NF-kappaB activation (CARD10, CARD14), and cyclin-dependent kinase inhibitors (p16 and p18)(2).

3. Skins and seed of grape and wine
In the study to investigate the effect of Resveratrol trans-3, 4', 5,-trihydroxystilbene, insuppressing the multiple myeloma (MM), found thatResveratrol activated IRE1α as evidenced by XBP1 messenger RNA splicing and phosphorylation of both IRE1α and its downstream kinase c-Jun N-terminal kinase in MM cells. These responses were associated with resveratrol-induced cytotoxicity of MM cells. Resveratrol selectively suppressed the transcriptional activity of XBP1s while it stimulated gene expression of the molecules that are regulated by the non-IRE1/XBP1 axis of the ER stress response. Luciferase assays indicated that resveratrol suppressed the transcriptional activity of XBP1s through sirtuin 1, a downstream molecular target of resveratrol. Chromatin immunoprecipitation studies revealed that resveratrol decreased the DNA binding capacity of XBP1 and increased the enrichment of sirtuin 1 at the XBP1 binding region in the XBP1 promoter(3).

4. Carrot
Retinoic acid found of a measure amount in carrot has a potential in prevent and treat Myeloma (Multiple Myenoma). Study showed that The inhibitory effect of cRA was significantly superior to tRA (P = 0.0129) and IFN-alpha, similar to IFN-gamma and DEX. The combinations of cRA + IFN alpha, tRA + IFN-gamma, tRA + DEX did not show any synergistic effect on myeloma proliferation. In contrast, the combination cRA + DEX (0.29 +/- 0.04, M +/- SEM) markedly increased the effect of both cRA and DEX used as single agents. Ig synthesis was not significantly affected by CRA, tRA, IFN-gamma and the combination tRA + IFN-gamma. As expected, only IFN-alpha (P = 0.002) and DEX (P < 0.001) inhibited Ig production(4).

5. Etc.

Chinese Food Therapy
The Best Way to prevent, treat your disease,
particular in treatment of menstrual disorder in Women Health

Sources
(1) http://www.ncbi.nlm.nih.gov/pubmed/12393461
(2) http://www.ncbi.nlm.nih.gov/pubmed/16809610
(3) http://www.ncbi.nlm.nih.gov/pubmed/21723843
(40 http://www.ncbi.nlm.nih.gov/pubmed/7734354

General Health: Cystitis - The Symptoms

Cystitis

Cystitis is defined as a condition of urinary bladder inflammation

The Symptoms

1. Pressure in the lower pelvis, daytime frequency and nocturia
Interstitial cystitis is is characterized by over 6 months of chronic pain, pressureand discomfort felt in the lower pelvis or bladder. It is often relieved with voiding, along with daytime frequency and nocturia in the absence of an urinary tract infection(1).

2. Painful urination (dysuria)
A slight majority of women with interstitial cystitis/painful bladder syndrome (IC/PBS) reported dysuria at onset of their IC/PBS symptoms. The available laboratory data have suggested that dysuria may be a sensitive indicator of urinary tract infection at the onset of IC/PBS(2).

3. Frequent urination (polyuria) or urgent need to urinate (urinary urgency)
It can be caused by overactive bladder as a result of irritation due to inflammatory cystitis

4. Haematuria
There is a report of a case of uncomplicated urinary tract infection due to Corynebacterium striatum in an ambulatory patient without any other predisponent risk factors(3).

5. Bladder/pelvic pain

6. Dark, cloudy or strong-smelling urine

7. Etc.

Chinese Food Therapy
The Best Way to prevent, treat your disease,
particular in treatment of menstrual disorder in Women Health

Sources
(1) http://www.ncbi.nlm.nih.gov/pubmed/20679058
(2) http://www.ncbi.nlm.nih.gov/pubmed/16979747
(3) http://www.ncbi.nlm.nih.gov/pubmed/19900386