Medical Advisor Journals

Wednesday, June 28, 2017

Thyroid hormone Analysis of patients with anaplastic thyroid cancer

Kyle J. Norton(Scholar and Master of Nutrients, all right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

Thyroid hormone

Thyroid hormone (triiodothyronine (T3) and thyroxine (T4)), produced by the thyroid gland, plays an important role in regulation of metabolism, including directly boosts energy metabolism and triggers rapid protein synthesis and regulates mitochondrial gene transcription, etc. Iodine is necessary for the production of T3and T4, deficiency of Iodine can lead to enlarge thyroid grand and goitre.

Thyroid hormone Analysis of patients with anaplastic thyroid cancer

In the study to to analyze the clinicopathologic characteristics of patients diagnosed with ATC expected to undergo curative thyroidectomy, with the goal of finding differences between patients surviving ≥6 months and <6 months, found that ATC showed female predominance. Patients initially presented with neck mass, and median age was 55 years. In patients with ATC who are expected to undergo curative thyroidectomy, surgery should actively be considered as primary therapy for patient survival when the size is <5 cm(61).

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Sources
(61) http://www.ncbi.nlm.nih.gov/pubmed/22977757

Tuesday, June 27, 2017

Thyroid hormone: Thyroid Nodule Size and Cancer

Thyroid hormone: Thyroid Nodule Size and Cancer

In the study to evaluate the association of nodule size upon cancer risk in a retrospective cohort analysis at an academic hospital with 4955 consecutive patients evaluated between 1995 and 2009, found that Increasing thyroid nodule size impacts cancer risk in a nonlinear fashion. A threshold is detected at 2.0 cm, beyond which cancer risk is unchanged. However, the risk of follicular carcinomas and other rare thyroid malignancies increases as nodules enlarge(60).

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Sources
(60) http://www.ncbi.nlm.nih.gov/pubmed/23275525

Monday, June 26, 2017

Thyroid hormone: Hereditary medullary thyroid carcinoma (HMTC)

Thyroid hormone: Hereditary medullary thyroid carcinoma (HMTC)

In the study to investigate the role of germline inheritance of polymorphisms in CYP1A2*F, CYP1A1m1, GSTP1, NAT2 and TP53 genes in hereditary medullarythyroid carcinoma (HMTC) patients of 132 patients with HMTC, 88 first-degree relatives of HMTC patients and 575 control individuals, found that
the inheritance of specific genes determining the individual response to environmental toxins may contribute to the risk and phenotypic variability that exists in patients with HMTC(59).

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Sources
(59) http://www.ncbi.nlm.nih.gov/pubmed/23278115

Sunday, June 25, 2017

Thyroid hormone: Thyroid disease in pregnancy and childhood

Thyroid hormone: Thyroid disease in pregnancy and childhood

Thyroid function in pregnancy is characterised by a T4 surge at 12 weeks declining thereafter. Fetal brain development depends on T4 transport into the fetus which in turn depends on sufficient maternal iodine supply. In the study to measure free T4 using direct equilibrium dialysis, as well as total T4 and TSH in 287 pregnant women at 27 weeks' gestation, found that Increasing maternal TSH was related to better performance on tests of cognition and language at 12 months but not at later ages. At 60 months, there was inconsistent evidence that higher TSH was related to improved attention. We found no convincing evidence that maternal TH during the second half of pregnancy was related to impaired child neurodevelopment(58).

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Sources
(58) http://www.ncbi.nlm.nih.gov/pubmed/22132346

Saturday, June 24, 2017

Thyroid hormone: Subclinical hypothyroidism in pregnancy

Thyroid hormone: Subclinical hypothyroidism in pregnancy

In the study to evaluate the intellectual development of children of mothers who had M-SCH during the pregnancy for these children with 68 children were recruited, after excluding those age < 4 or age > 15, 44, found that IQ level and cognitive performance of children born to LT4-treated hypothyroid mothers is similar in those whose mothers have M-SCH during pregnancy compared with those whose mothers have normal serum TSH concentrations during pregnancy(57).

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Sources
(57) http://www.ncbi.nlm.nih.gov/pubmed/21943136

Friday, June 23, 2017

Thyroid hormone: Thyroid physiology and common diseases in pregnancy

Thyroid hormone: Thyroid physiology and common diseases in pregnancy

Thyroid diseases are common during pregnancy and an adequate treatment is important to prevent adverse maternal and fetal outcomes, such as neurodevelopment complications in the fetus. According to the study by Artemisia Fetal-Maternal Medical Center, found that large-scale intervention trials are urgently needed to assess the efficacy of preconception or early pregnancy screening for thyroid disorders. Accurate interpretation of both antepartum and postpartum levels of thyroid hormones is important in preventing pregnancy-related complication secondary to thyroid dysfunction(56).

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Sources
(56) http://www.ncbi.nlm.nih.gov/pubmed/22419883

Thursday, June 22, 2017

Thyroid hormone: Thyroid hormone levels and vegetative dysfunction and heart connective tissue dysplasia (HCTD)

Thyroid hormone: Thyroid hormone levels and vegetative dysfunction and heart connective tissue dysplasia (HCTD)

Heart connective tissue dysplasia (HCTD) are known to be subject to infectious and inflammatory diseases due to peculiarities of their immune system. In the study of 181 patients with HCTD depending on thyroid hormone levels and vegetative dysfunction. indicated that HCTD was shown to be associated with a significant decrease of IgM levels and increase of circulating immune complexes. The IgG level in patients with mitral valve prolapse (MVP), anomalous chord localization, and combination of MPV and tricuspid valve prolapse was significantly higher than in the absence of HCTD(55).

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Sources
(55) http://www.ncbi.nlm.nih.gov/pubmed/23285764