Arnica may have a potential and therapeutic effect in reduced expression of Ecchymosis, some scientists suggested.
The results of these efficacy were confirmed by some studies conducted by numbers of respectable institutes, including University of Miami Miller School of Medicine and University of South Florida.
Ecchymosis is a condition of discoloration of the skin as a result of bleeding underneath. In most cases it is caused by bruising.
Arnica is a herbaceous species, genus perennial, belongings to the family Asteraceae, antive to Europe and Asia, used in herbal medicine for centuries to treat strains, sprains, and bruises.
Wound healing is process of repairing of damage of skin, tissues, organs, etc.
The ingredients
Helenalin, chamissonolid, Sesquiterpene lactone, lignans of the furofuran, dibenzylbutyrolactone, dibenzylbutyrolactol types, pinoresinol, epipinoresinol, phillygenin, matairesinol, nortrachelogenin, and nortracheloside, six dibenzylbutyrolactol derivative.
In order to confirm the effect of herbal Arnice activity in treatment of ecchymosis in patients who under went rhinoplasty, the most common facial plastic surgical procedure, researchers at the joint study lead by the University of South Florida independently conducted a review of literature in databases (PubMed, SCOPUS, Embase, Web of Science, and the Cochrane database) from inception to September 2016, included studies that compared postoperative care methods (intervention groups) with no treatment (control group).
According to the final searching of 11 trials satisfied the criteria and guideline with a total of 627 patients, application of topical Arnica showed a significant effect in reduced eyelid ecchymosis during the first 7 days postoperative statistically in compared to the control group.
However, eyelid ecchymosis during the first 24 h postoperatively were statistically decreased in the cold compression group in compared to the control and treatment group.
Patients' questionnaires returned also expressed a strong satisfaction in the tapping application group than in the control group.
Also, the ratio of patient satisfaction was statistically higher in the tapping and Arnica application group than those of control.
Additionally, the analysis also found that surgeons had a significant tendency to decrease intranasal packing in remove pain from the surgery area as the placement was found to associate with more adverse effects in terms of postoperative ecchymosis in compared to non-packing.
Further differentiation to confirm the effectiveness of the combination of topical Arnica montana and Rhododendron tomentosum (Ledum palustre) in reducing postoperative ecchymosis in a select population of healthy volunteers after oculofacial surgery, researchers launched a review to examine the postoperative course, using topical Arnica and Ledum after undergoing common oculofacial procedures, including blepharoplasty, browpexy, and rhinoplasty, in the hands of 4 surgeons at tertiary referral centers from July 1, 2012 to December 31, 2012.
A total of 27 patients (16 females, 11 males) with age range of 18 to 70 years were included in the study.
Selected medical review showed that patients applied bilaterally topical hydrogel pads (OcuMend, Cearna Inc., Chicago, IL) containing Arnica 50 M (10) 50% and Ledum 50 M (10) after surgery through postoperative day(POD) 6 at each postoperative visit.
These results of everyday progression in patients were evaluated by their respective surgeons.
The physician-patient rating score were used to compare each patient's observed healing in each group.
Photographs in each examination also were recorded.
The median duration of follow-up was 7 days, range from 1 to 14 days.
According to the rating of final examination,
* The proportions of patients with markedly accelerated healing were 38.5% (5 of 13), 85.7% (6 of 7), 60.0% (12 of 20), and 51.9% (14 of 27) at POD 1 to 2, 3 to 5, 6 to 8, and overall, respectively.
* The proportions of patients with accelerated healing at the same time points were 15.4% (2 of 13), 14.3% (1 of 7), 30.0% (6 of 20), and 37.0% (10 of 27), respectively.
* The proportion of patients using Arnica/Ledum with markedly accelerated healing was significantly higher than the over all and time point proportion of the other groups at (post operative day) POD 3 to 5 (85.7%), POD 6 to 8 (60.0% ), and overall (51.9%) without inducing any adverse effects.
The findings suggested that combination of Arnica/Ledum were more effective in compared to other treatments.
Dr. Lee HS, the lead author said, "The preliminary results from this study demonstrate that the combination of topical Arnica montana and Rhododendron tomentosum (Ledum palustre) may be effective in reducing postoperative ecchymosis...., after oculofacial surgery".
Taken together, topical Arnica may be used alone or combined with other herbal medicine to accelerate the healing of ecchymosis
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Loose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Home page http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrients, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.
Sources
(1) Assessing the Effectiveness of Arnica montana and Rhododendron tomentosum (Ledum palustre) in the Reduction of Ecchymosis and Edema After Oculofacial Surgery: Preliminary Results by Kang JY1, Tran KD, Seiff SR, Mack WP, Lee WW.(PubMed)
(2) The effectiveness of postoperative intervention in patients after rhinoplasty: a meta-analysis by Lee HS1, Yoon HY1, Kim IH1, Hwang SH2.(PubMed)
(3) Is There a Role for Arnica and Bromelain in Prevention of Post-Procedure Ecchymosis or Edema? A Systematic Review of the Literature by Ho D1, Jagdeo J, Waldorf HA.(PubMed)
Saturday, September 29, 2018
Friday, September 28, 2018
How to Prevent Vulvar Cancer Naturally
Adding a portion of carrots in women daily diet may have a profound and positive effect in reduced risk, progression and treatment of vulvar cancer, some scientists suggested.
The investigations were conduced by numbers of respectable university in women associated to higher risk of vulvar cancers, including the Tampere University Central Hospital and Mercer University and the results were published on online literature.
You can view the detail in abstracts of the studies by clicking any of the resources link
Vulvar cancer is a medical condition characterized by cell growth irregularly and disorderly in the tissue of the area of skin surrounded the urethra and vagina, including the clitoris and labia.
At the later stage, the cancerous cells may travel a distance away from the original site to infectious other healthy tissue.
The results of evaluation were reported by some respectable institutes and published on the online medical literature.
Carrot, a root vegetable with orange color is a sub spices of Daucus carota, belongings to the family Apiaceae, native to Asian and Europe.
Nutrients
1. Carbohydrates
2. Sugars
3. Fibre
4. Fat
5. Protein
6. Vitamin A
7. Thiamine (VittaminB1)
8. Riboflavin (Vittamin B2)
9. Niacin (Vittamin B3)
10. Vitamin B6
11. Folate (Vittamin B9)
12. Vitamin C
13. Vitamin K
14. Calcium
15. Iron
16. Magnesium
17. Molybdenum
18. Phosphorus
19. Potassium
20. Sodium
In the study to analyze the association between body mass, selected indicator food intake, and vulvar cancer risk of 125 women aged 80 years or younger with histologically confirmed diagnosis of invasive vulvar cancer, admitted to a network of general and teaching hospitals in the greater Milan area in compared to Control subjects of 541 patients admitted to teaching and general hospitals in Milan for acute conditions, researcher found that carrot consumption is associated to reduce risk of the cancer.
In compared to others in exerted inconsistent association of risk of vulvar cancer such as milk, meat, liver, alcohol and coffee consumption, carrot demonstrated a significantly decreased risk ratio of 1.4.
The results suggest that certain factors in the dietary and nutritional aspects may process related mechanisms in risk of vulvar cancer.
Further analysis of carrot effect in risk of vulvar cancer inregard of the micro nutrients expression, researchers found that serum concentrations of vitamin A (retinol), vitamin E (alpha-tocopherol) and total carotene were lower in women with vulvar cancer but no difference to women with other types of female reproductive cancer such as cervical, endometrial and ovarian carcinomas.
In compared to healthy control, the mean levels of vitamin A was significantly less in patients with vulvar cancer.
However, according to the Mercer University, in analysis of the patients with metastasising carcinoma of the uterine cervix or recurrent disease after failure of surgical and/or radiation and chemotherapy therapy.
13-cis-retinoic acid and interferon alpha-2 a in the treatment of squamous cell carcinoma of the cervix in 6 patients with locally recurrent or metastasising squamous cell carcinomas, five of the uterine cervix, one of the vulva. in the period of 52 days, median survival time 107 days, filed the results as follows
* 3 women experienced progression of disease uninfluenced by therapy.
* 1 patient with multiple subcutaneous lymph node metastases showed mixed response for a short period of 3 weeks before progression and eventual death.
* 1 patient had no change or disease for 13 months with subsequent progression and eventual death after 22 months.
* One patient could not be evaluated for an allergic reaction after only 15 days of treatment.
The application also induced adverse effects of "flu-like symptoms", skin irritations, conjunctivitis sicca and chileitis, all WHO 1-2.
Overall toxicity is extremely low in compared to standard chemotherapy, but is not negligible.
The failure of study in treatment of advance vulvar cancer may be due to numbers of implication, researchers at the Mercer University suggested , "this might be due to the small number of cases, which is a common problem in immunotherapeutic studies. Moreover, very unfavourable patient selection criteria in our study compared to primarily untreated patients may also have contributed to different response rates. However, in our opinion the tested regimen cannot be considered sufficiently effective in patients suffering from pretreated, recurrent squamous cell carcinoma of the cervix or vulva".
Taken together, Carrot with high amount of nutrients and antioxidants may be used as functional food in reduced risk and combined with standard therapy for treatment of vulvar cancer. However, multi centers and large sample size studies are necessary to re confirm this viability.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Loose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Home page http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299
Sources
(1) Selected food intake and risk of vulvar cancer by Parazzini F1, Moroni S, Negri E, La Vecchia C, Dal Pino D, Cavalleri E.(PubMed)
(2) Serum vitamins A and E and carotene in patients with gynecologic cancer by Heinonen PK1, Kuoppala T, Koskinen T, Punnonen R.(PubMed)
(3) [13-cis retinoic acid and interferon-alfa-2a as palliative therapy in pretreated, recurrent squamous epithelial carcinoma of the cervix uteri and vulva] by [Article in German](PubMed)
The investigations were conduced by numbers of respectable university in women associated to higher risk of vulvar cancers, including the Tampere University Central Hospital and Mercer University and the results were published on online literature.
You can view the detail in abstracts of the studies by clicking any of the resources link
Vulvar cancer is a medical condition characterized by cell growth irregularly and disorderly in the tissue of the area of skin surrounded the urethra and vagina, including the clitoris and labia.
At the later stage, the cancerous cells may travel a distance away from the original site to infectious other healthy tissue.
The results of evaluation were reported by some respectable institutes and published on the online medical literature.
Carrot, a root vegetable with orange color is a sub spices of Daucus carota, belongings to the family Apiaceae, native to Asian and Europe.
Nutrients
1. Carbohydrates
2. Sugars
3. Fibre
4. Fat
5. Protein
6. Vitamin A
7. Thiamine (VittaminB1)
8. Riboflavin (Vittamin B2)
9. Niacin (Vittamin B3)
10. Vitamin B6
11. Folate (Vittamin B9)
12. Vitamin C
13. Vitamin K
14. Calcium
15. Iron
16. Magnesium
17. Molybdenum
18. Phosphorus
19. Potassium
20. Sodium
In the study to analyze the association between body mass, selected indicator food intake, and vulvar cancer risk of 125 women aged 80 years or younger with histologically confirmed diagnosis of invasive vulvar cancer, admitted to a network of general and teaching hospitals in the greater Milan area in compared to Control subjects of 541 patients admitted to teaching and general hospitals in Milan for acute conditions, researcher found that carrot consumption is associated to reduce risk of the cancer.
In compared to others in exerted inconsistent association of risk of vulvar cancer such as milk, meat, liver, alcohol and coffee consumption, carrot demonstrated a significantly decreased risk ratio of 1.4.
The results suggest that certain factors in the dietary and nutritional aspects may process related mechanisms in risk of vulvar cancer.
Further analysis of carrot effect in risk of vulvar cancer inregard of the micro nutrients expression, researchers found that serum concentrations of vitamin A (retinol), vitamin E (alpha-tocopherol) and total carotene were lower in women with vulvar cancer but no difference to women with other types of female reproductive cancer such as cervical, endometrial and ovarian carcinomas.
In compared to healthy control, the mean levels of vitamin A was significantly less in patients with vulvar cancer.
However, according to the Mercer University, in analysis of the patients with metastasising carcinoma of the uterine cervix or recurrent disease after failure of surgical and/or radiation and chemotherapy therapy.
13-cis-retinoic acid and interferon alpha-2 a in the treatment of squamous cell carcinoma of the cervix in 6 patients with locally recurrent or metastasising squamous cell carcinomas, five of the uterine cervix, one of the vulva. in the period of 52 days, median survival time 107 days, filed the results as follows
* 3 women experienced progression of disease uninfluenced by therapy.
* 1 patient with multiple subcutaneous lymph node metastases showed mixed response for a short period of 3 weeks before progression and eventual death.
* 1 patient had no change or disease for 13 months with subsequent progression and eventual death after 22 months.
* One patient could not be evaluated for an allergic reaction after only 15 days of treatment.
The application also induced adverse effects of "flu-like symptoms", skin irritations, conjunctivitis sicca and chileitis, all WHO 1-2.
Overall toxicity is extremely low in compared to standard chemotherapy, but is not negligible.
The failure of study in treatment of advance vulvar cancer may be due to numbers of implication, researchers at the Mercer University suggested , "this might be due to the small number of cases, which is a common problem in immunotherapeutic studies. Moreover, very unfavourable patient selection criteria in our study compared to primarily untreated patients may also have contributed to different response rates. However, in our opinion the tested regimen cannot be considered sufficiently effective in patients suffering from pretreated, recurrent squamous cell carcinoma of the cervix or vulva".
Taken together, Carrot with high amount of nutrients and antioxidants may be used as functional food in reduced risk and combined with standard therapy for treatment of vulvar cancer. However, multi centers and large sample size studies are necessary to re confirm this viability.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Loose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Home page http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299
Sources
(1) Selected food intake and risk of vulvar cancer by Parazzini F1, Moroni S, Negri E, La Vecchia C, Dal Pino D, Cavalleri E.(PubMed)
(2) Serum vitamins A and E and carotene in patients with gynecologic cancer by Heinonen PK1, Kuoppala T, Koskinen T, Punnonen R.(PubMed)
(3) [13-cis retinoic acid and interferon-alfa-2a as palliative therapy in pretreated, recurrent squamous epithelial carcinoma of the cervix uteri and vulva] by [Article in German](PubMed)
Thursday, September 27, 2018
How to Prevent and Treat Infectious Diseases Naturally and Effectively
Including green tea as a beverage in your diet may have a therapeutic and positive effect in reduced risk and treatment of bacterial and viral infectious diseases, some scientists suggested.
The results of the analysis were carried out by numbers of institutes, including the Yonsei University and punished on online medical literature.
Green tea, is a precious drink processed numbers of health benefit known to almost everyone in Asia and Western world.
According to Review provided by VeriMed Healthcare Network. intake of green tea 2 to 4 cups per day by steep covered 5 to 10 minutes for leaf or flowers and 10 to 20 minutes for roots was associated to support immunity while providing antibacterial and antiviral activity.
Also, green tea (Camellia sinensis) extract of 250 to 500 mg daily, enhanced immune function due to its antioxidant, anti-inflammatory, and immune effects.
Moreover, tannin, green tea derived polyphenols and other related compounds, in the study to investigate the anti-viral effects of tannins on 12 different viruses including both enveloped viruses (influenza virus H3N2, H5N3, herpes simplex virus-1, vesicular stomatitis virus, Sendai virus and Newcastle disease virus) and non-enveloped viruses (poliovirus, coxsachievirus, adenovirus, rotavirus, feline calicivirus and mouse norovirus) researchers suggested that application of tannin reduced some viral infectivity in compared to persimmon (Diospyros kaki) with more than 4-log scale against all of the viruses tested.
More importantly, the differentiation of epigallocatechin-3-gallate (EGCG) effect against viral infections also indicated that EGCG injection in solution type and powder types over extended periods at various temperature conditions exerts a strong effect in inhibited the tested human influenza A/H1N1 virus.
Green tea extract in the study also demonstrated potent viral inactivating activity for over a period of up to 2 months.
These results suggested that adding green tea supplement GTE may provide a greater than 4 log10 reduction of viral titers at a wide range of temperatures.
Dr. Lee YH, after taking intoaccount of other co and confouders said, "GTE-based antiviral agents could be formulated as a safe and environmentally friendly personal hygiene against viral infections".
The findings showed that green tea and green tea extract may be considered as function foods in reduced risk and treatment of infectious diseases caused by bacterial and viral invasion.
However, intake of green tea supplementation should be taken with extreme care as acute liver toxicity has been reported in numbers of cases.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Loose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Home page http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299
Sources
(1) Measle Reviewed By: Steven D. Ehrlich, NMD, Solutions Acupuncture, a private practice specializing in complementary and alternative medicine, Phoenix, AZ. Review provided by VeriMed Healthcare Network.
(2) Inactivation of Pathogenic Viruses by Plant-Derived Tannins: Strong Effects of Extracts from Persimmon (Diospyros kaki) on a Broad Range of Viruses
Kyoko Ueda, 1 Ryoko Kawabata, 1 Takashi Irie, 1 Yoshiaki Nakai, 2 Yukinobu Tohya, 3 and Takemasa Sakaguchi 1 (PMC)
(2) Evaluation of green tea extract as a safe personal hygiene against viral infections by Lee YH#1, Jang YH#1, Kim YS1, Kim J2,3, Seong BL1,4.(PubMed)
The results of the analysis were carried out by numbers of institutes, including the Yonsei University and punished on online medical literature.
Green tea, is a precious drink processed numbers of health benefit known to almost everyone in Asia and Western world.
According to Review provided by VeriMed Healthcare Network. intake of green tea 2 to 4 cups per day by steep covered 5 to 10 minutes for leaf or flowers and 10 to 20 minutes for roots was associated to support immunity while providing antibacterial and antiviral activity.
Also, green tea (Camellia sinensis) extract of 250 to 500 mg daily, enhanced immune function due to its antioxidant, anti-inflammatory, and immune effects.
Moreover, tannin, green tea derived polyphenols and other related compounds, in the study to investigate the anti-viral effects of tannins on 12 different viruses including both enveloped viruses (influenza virus H3N2, H5N3, herpes simplex virus-1, vesicular stomatitis virus, Sendai virus and Newcastle disease virus) and non-enveloped viruses (poliovirus, coxsachievirus, adenovirus, rotavirus, feline calicivirus and mouse norovirus) researchers suggested that application of tannin reduced some viral infectivity in compared to persimmon (Diospyros kaki) with more than 4-log scale against all of the viruses tested.
More importantly, the differentiation of epigallocatechin-3-gallate (EGCG) effect against viral infections also indicated that EGCG injection in solution type and powder types over extended periods at various temperature conditions exerts a strong effect in inhibited the tested human influenza A/H1N1 virus.
Green tea extract in the study also demonstrated potent viral inactivating activity for over a period of up to 2 months.
These results suggested that adding green tea supplement GTE may provide a greater than 4 log10 reduction of viral titers at a wide range of temperatures.
Dr. Lee YH, after taking intoaccount of other co and confouders said, "GTE-based antiviral agents could be formulated as a safe and environmentally friendly personal hygiene against viral infections".
The findings showed that green tea and green tea extract may be considered as function foods in reduced risk and treatment of infectious diseases caused by bacterial and viral invasion.
However, intake of green tea supplementation should be taken with extreme care as acute liver toxicity has been reported in numbers of cases.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Loose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Home page http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299
Sources
(1) Measle Reviewed By: Steven D. Ehrlich, NMD, Solutions Acupuncture, a private practice specializing in complementary and alternative medicine, Phoenix, AZ. Review provided by VeriMed Healthcare Network.
(2) Inactivation of Pathogenic Viruses by Plant-Derived Tannins: Strong Effects of Extracts from Persimmon (Diospyros kaki) on a Broad Range of Viruses
Kyoko Ueda, 1 Ryoko Kawabata, 1 Takashi Irie, 1 Yoshiaki Nakai, 2 Yukinobu Tohya, 3 and Takemasa Sakaguchi 1 (PMC)
(2) Evaluation of green tea extract as a safe personal hygiene against viral infections by Lee YH#1, Jang YH#1, Kim YS1, Kim J2,3, Seong BL1,4.(PubMed)
Wednesday, September 26, 2018
How to Treat Lower Back Pain Efficiently and Naturally
Green tea and its bioactive catechin epigallocatechin 3-gallate (EGCG) may have a therapeutic and positive effect in ameliorated symptoms and treatment of chronic back pain, some scientists suggested.
Green tea is a precious drink processes numbers of health benefit known to almost everyone in Asia and Western world.
Back pain is a condition of Musculo-Skeletal disorders(MSDs) of the spine caused by various factors, including bone fractures, muscle or ligament injure, arthritis, herniated discs. aging,....
Application of biologically active polyphenol epigallocatechin 3-gallate (EGCG) demonstrated a significant effect in reduced back pain through facilitate anti inflammatory and anti-catabolic activity in patients with intervertebral disc (IVD) disease due to age-related changes in the adult disc in induction of back pain.
According to the study by the Institute for Biomechanics (D-HEST), ETH Zurich ingestion of green tea EGCG on back pain patients, human IVD cells isolated from patients undergoing surgery due to degenerative disc disease (n = 34) and cultured in 2D or 3D indicated that the phytochemical inhibited levels of inflammatory response activated by IL-1β, a cytokine protein produced by macrophages, with function in contributed to the inflammatory pain hypersensitivity in the site of infection observed by the reverse transcription polymerase chain reaction (qRT-PCR), western blotting, enzyme-linked immunosorbent assay (ELISA), immunofluorescence and transcription factor assay.
Further more, application also displayed a strong effect in reduced expression of
p38 mitogen-activated protein kinases in mediated inflammatory factors of IL-1β in responded to stress stimuli.
Also, according to the Institute for Biomechanics (D-HEST), in the investigation of the analgesic properties of EGCG, by the von Frey filament test in Sprague-Dawley rats (n = 60), green tea EGCG injection also significantly inhibited the expression of pro-inflammatory mediators as expressed in above and reduced matrix metalloproteinases which have been found to associate to pro-inflammatory cytokines, chemokines and other proteins to regulate varied aspects of inflammation and immunity.
Moreover, in the radiculopathic pain component, researchers also indicated that EGCG inhibited the inflammation in precipitated back pain through modulation of the activity of IRAK-1 in glucose metabolism and insulin sensitivity in skeletal muscle and p38, c-Jun N-terminal kinases (JNK) and nuclear factor NF-κB in responded to stress stimuli in mediated production of pain related pro inflammatory cytokines such as IL-1β.
Some researchers postulated that back pain may also induced by muscle degeneration and impairment nerve injury, leading to increased levels of reactive oxygen species in induced tissue apoptosis.
In crushing of the sciatic nerve induced back pain in tested animal, application of green tea EGCG improved motor function in the toe spread and foot positioning and gain in the percentage motor deficit.
More importantly, EGCG expressed a significant effect in recovery of sensory innervation in neuropathic pain-like syndrome and improvement of muscle tissues from injured limb with severe histopathological alterations at the end of week 3 post-surgery in treated animals.
According to the RT-PCR assay, EGCG treatment also normalizing the Bax/Bcl-2 ratio, abnormal ratio of the Bax/Bcl-2 ratio has been found to associate in induction of nerve cell apoptosis as well as inhibited levels of p53 with function in regulated the cell death cycle at days 3 and 7 post-surgery.
These results demonstrated a important effect of green tea EGCG in enhanced functional recovery, protected muscle fibers from cellular death, and improved morphological recovery in skeletal muscle after nerve injuries.
However, in the study of caffeine activity in the modulation of pain perception in chronic pain states of 131 patients with chronic low back pain (64 men and 67 women; mean age = 42.1 years; mean duration of pain = 6.1 years) referred to a multidisciplinary pain clinic over a 2-year period, researchers found that in compared to caffeine intake regardless concentration, cffeine is not related to the global experience of pain and disability in patients with chronic low back pain, although high caffeine use may be embedded in a context of other unhealthy life-style behaviors.
Taken together, green tea and its bioactive component epigallocatechin 3-gallate (EGCG) may be considered as functional food in reduced back pain caused by physical damage of the spine and injured nerve cells. Intake of green tea supplement should be taken exceptional care as some cases of liver acute toxicity have been reported in medical literature.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Loose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Home page http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.
Sources
(1) Epigallocatechin 3-gallate suppresses interleukin-1β-induced inflammatory responses in intervertebral disc cells in vitro and reduces radiculopathic pain in rats by Krupkova O1, Sekiguchi M, Klasen J, Hausmann O, Konno S, Ferguson SJ, Wuertz-Kozak K.(PubMed)
(2) (-)-Epigallocatechin-3-gallate (EGCG) attenuates functional deficits and morphological alterations by diminishing apoptotic gene overexpression in skeletal muscles after sciatic nerve crush injury by Renno WM1, Al-Maghrebi M, Al-Banaw A.(PubMed)
(3) Caffeine and chronic low back pain by Currie SR1, Wilson KG, Gauthier ST.(PubMed)
Green tea is a precious drink processes numbers of health benefit known to almost everyone in Asia and Western world.
Back pain is a condition of Musculo-Skeletal disorders(MSDs) of the spine caused by various factors, including bone fractures, muscle or ligament injure, arthritis, herniated discs. aging,....
Application of biologically active polyphenol epigallocatechin 3-gallate (EGCG) demonstrated a significant effect in reduced back pain through facilitate anti inflammatory and anti-catabolic activity in patients with intervertebral disc (IVD) disease due to age-related changes in the adult disc in induction of back pain.
According to the study by the Institute for Biomechanics (D-HEST), ETH Zurich ingestion of green tea EGCG on back pain patients, human IVD cells isolated from patients undergoing surgery due to degenerative disc disease (n = 34) and cultured in 2D or 3D indicated that the phytochemical inhibited levels of inflammatory response activated by IL-1β, a cytokine protein produced by macrophages, with function in contributed to the inflammatory pain hypersensitivity in the site of infection observed by the reverse transcription polymerase chain reaction (qRT-PCR), western blotting, enzyme-linked immunosorbent assay (ELISA), immunofluorescence and transcription factor assay.
Further more, application also displayed a strong effect in reduced expression of
p38 mitogen-activated protein kinases in mediated inflammatory factors of IL-1β in responded to stress stimuli.
Also, according to the Institute for Biomechanics (D-HEST), in the investigation of the analgesic properties of EGCG, by the von Frey filament test in Sprague-Dawley rats (n = 60), green tea EGCG injection also significantly inhibited the expression of pro-inflammatory mediators as expressed in above and reduced matrix metalloproteinases which have been found to associate to pro-inflammatory cytokines, chemokines and other proteins to regulate varied aspects of inflammation and immunity.
Moreover, in the radiculopathic pain component, researchers also indicated that EGCG inhibited the inflammation in precipitated back pain through modulation of the activity of IRAK-1 in glucose metabolism and insulin sensitivity in skeletal muscle and p38, c-Jun N-terminal kinases (JNK) and nuclear factor NF-κB in responded to stress stimuli in mediated production of pain related pro inflammatory cytokines such as IL-1β.
Some researchers postulated that back pain may also induced by muscle degeneration and impairment nerve injury, leading to increased levels of reactive oxygen species in induced tissue apoptosis.
In crushing of the sciatic nerve induced back pain in tested animal, application of green tea EGCG improved motor function in the toe spread and foot positioning and gain in the percentage motor deficit.
More importantly, EGCG expressed a significant effect in recovery of sensory innervation in neuropathic pain-like syndrome and improvement of muscle tissues from injured limb with severe histopathological alterations at the end of week 3 post-surgery in treated animals.
According to the RT-PCR assay, EGCG treatment also normalizing the Bax/Bcl-2 ratio, abnormal ratio of the Bax/Bcl-2 ratio has been found to associate in induction of nerve cell apoptosis as well as inhibited levels of p53 with function in regulated the cell death cycle at days 3 and 7 post-surgery.
These results demonstrated a important effect of green tea EGCG in enhanced functional recovery, protected muscle fibers from cellular death, and improved morphological recovery in skeletal muscle after nerve injuries.
However, in the study of caffeine activity in the modulation of pain perception in chronic pain states of 131 patients with chronic low back pain (64 men and 67 women; mean age = 42.1 years; mean duration of pain = 6.1 years) referred to a multidisciplinary pain clinic over a 2-year period, researchers found that in compared to caffeine intake regardless concentration, cffeine is not related to the global experience of pain and disability in patients with chronic low back pain, although high caffeine use may be embedded in a context of other unhealthy life-style behaviors.
Taken together, green tea and its bioactive component epigallocatechin 3-gallate (EGCG) may be considered as functional food in reduced back pain caused by physical damage of the spine and injured nerve cells. Intake of green tea supplement should be taken exceptional care as some cases of liver acute toxicity have been reported in medical literature.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Loose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Home page http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.
Sources
(1) Epigallocatechin 3-gallate suppresses interleukin-1β-induced inflammatory responses in intervertebral disc cells in vitro and reduces radiculopathic pain in rats by Krupkova O1, Sekiguchi M, Klasen J, Hausmann O, Konno S, Ferguson SJ, Wuertz-Kozak K.(PubMed)
(2) (-)-Epigallocatechin-3-gallate (EGCG) attenuates functional deficits and morphological alterations by diminishing apoptotic gene overexpression in skeletal muscles after sciatic nerve crush injury by Renno WM1, Al-Maghrebi M, Al-Banaw A.(PubMed)
(3) Caffeine and chronic low back pain by Currie SR1, Wilson KG, Gauthier ST.(PubMed)
Tuesday, September 25, 2018
How to Optimize Your Immune Functioning Against Pathogens, Scientists Say
Including a portion of lentil in your diet will have a profound and substantial effect in modulated immune response in acute phase of infection, some scientist suggested
Lentil is a type of pulse and tiny legumes that can be cooked quickly and rich in protein and fiber, belongings genus Lens the Fabaceae family, native to Middle East.
Immune response is a natural reaction of immune system to protect our body against invasion of foreign substances.
In acute phase of infection, immune system initiated production of of proinflammatory Th1 cytokines in activated interleukin-12 (IL-12) and gamma interferon (IFN-γ) and other pro inflammatory factors such as TNF beta in response to detect, engulf and destroy pathogens and apoptotic cells through macrophages.
These activities played an important in induced apoptosis and reduced proliferation of bacteria or virus by attaching to the surface of the injure cells to initiation of alternation. however, over production of pro inflammatory expression may indeed cause substantial adverse effects in tissue destruction, and, in some cases, shock and death.
Type 1 T helper (Th1) in response to tissue damage and injure also activated macrophages which are responsible for cell-mediated immunity and phagocyte-dependent protective activity.
In the concerns of lectins adverse effecs may pose a potential threat to consumers due to their capacity to induce histamine release from basophils, after investigating over 16 common dietary produceds containing lectins researchers found that most plant lectins induce human basophils to produce interleukin 4 (IL-4) a anti inflammatory cytokine, which plays an important role in stimulated secretion of T cells and IL-13 another cytokines works conjunction with IL-4 in promoted the expression of T helper 2 (Th2) responses and regulation of Immunoglobulin E (IgE) synthesis.
All these expressed a significant effect of dietary lectin in reduced over expression of pro inflammatory factors in immune system during acute phase of infection in induced further cell damage and death in the infectious site through secretion of anti inflammatory cytokines without decreasing the immune protective activities.
Truly, further examine also found that concanavalin A, lentil lectin, phytohemagglutinin, , triggered basophils to release IL-4 at concentrations of up to 1 ng/10(6) basophils which in turn orchestrated the release of IL-13 and histamine and levels of IL-4 and IL-13 release reached a maximum after 4-6 h and more than 18 h, after injection, , respectively.
These activities demonstrated a significant effect of lentil lectin in inducing early IL-4 required to switch the immuneresponse towards a Th2 response and type I allergy, involving immunoglobulin E (IgE)–mediated release of histamine and other mediators from mast cells and basophils.
Indeed, the relative balance between Th1 and Th2 cytokines appears crucial, as Th1 cells activated immune response during the early state of body injure or damage through evoking cell-mediated immunity and phagocyte-dependent inflammation, in stimulated production of several pro inflammatory cytokines such as interferon (IFN)-gamma, interleukin (IL)-2 and tumor necrosis factor (TNF)-beta which may also cause damage to the cell of the infectious region, leading to permanently additional damage to the tissues and Th2, under response to over expression of pro inflammatory cytokines stimulated the production of IL-4, IL-5, IL-6, IL-9, IL-10, and IL-13 of anti inimflammatory mytokines in evoked strong antibody responses (including those of the IgE class) and eosinophil accumulation, and inhibited several functions of phagocytic cells as indicated above.
Taken together, Lentil lectin may have a anti inflammatory effect in reduced over expression of pro inflammatory factors in initiation of symptoms of fever, headache, swelling, redness, loss of appetite, muscle stiffness through activating production of anti inflammatory mytokines.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Loose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Home page http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.
Sources
(1) Role of Th1 and Th2 Cytokines in Immune Response to Uncomplicated Plasmodium falciparum Malaria by Donato Torre,1,* Filippo Speranza,1 Massimo Giola,1 Alberto Matteelli,2 Roberto Tambini,1 andGilberto Biondi1(PMC)
(2) Dietary lectins can induce in vitro release of IL-4 and IL-13 from human basophils by Haas H1, Falcone FH, Schramm G, Haisch K, Gibbs BF, Klaucke J, Pöppelmann M, Becker WM, Gabius HJ, Schlaak M.(PubMed)
(3) T-cell subsets (Th1 versus Th2) by Romagnani S1(PubMed)
Lentil is a type of pulse and tiny legumes that can be cooked quickly and rich in protein and fiber, belongings genus Lens the Fabaceae family, native to Middle East.
Immune response is a natural reaction of immune system to protect our body against invasion of foreign substances.
In acute phase of infection, immune system initiated production of of proinflammatory Th1 cytokines in activated interleukin-12 (IL-12) and gamma interferon (IFN-γ) and other pro inflammatory factors such as TNF beta in response to detect, engulf and destroy pathogens and apoptotic cells through macrophages.
These activities played an important in induced apoptosis and reduced proliferation of bacteria or virus by attaching to the surface of the injure cells to initiation of alternation. however, over production of pro inflammatory expression may indeed cause substantial adverse effects in tissue destruction, and, in some cases, shock and death.
Type 1 T helper (Th1) in response to tissue damage and injure also activated macrophages which are responsible for cell-mediated immunity and phagocyte-dependent protective activity.
In the concerns of lectins adverse effecs may pose a potential threat to consumers due to their capacity to induce histamine release from basophils, after investigating over 16 common dietary produceds containing lectins researchers found that most plant lectins induce human basophils to produce interleukin 4 (IL-4) a anti inflammatory cytokine, which plays an important role in stimulated secretion of T cells and IL-13 another cytokines works conjunction with IL-4 in promoted the expression of T helper 2 (Th2) responses and regulation of Immunoglobulin E (IgE) synthesis.
All these expressed a significant effect of dietary lectin in reduced over expression of pro inflammatory factors in immune system during acute phase of infection in induced further cell damage and death in the infectious site through secretion of anti inflammatory cytokines without decreasing the immune protective activities.
Truly, further examine also found that concanavalin A, lentil lectin, phytohemagglutinin, , triggered basophils to release IL-4 at concentrations of up to 1 ng/10(6) basophils which in turn orchestrated the release of IL-13 and histamine and levels of IL-4 and IL-13 release reached a maximum after 4-6 h and more than 18 h, after injection, , respectively.
These activities demonstrated a significant effect of lentil lectin in inducing early IL-4 required to switch the immuneresponse towards a Th2 response and type I allergy, involving immunoglobulin E (IgE)–mediated release of histamine and other mediators from mast cells and basophils.
Indeed, the relative balance between Th1 and Th2 cytokines appears crucial, as Th1 cells activated immune response during the early state of body injure or damage through evoking cell-mediated immunity and phagocyte-dependent inflammation, in stimulated production of several pro inflammatory cytokines such as interferon (IFN)-gamma, interleukin (IL)-2 and tumor necrosis factor (TNF)-beta which may also cause damage to the cell of the infectious region, leading to permanently additional damage to the tissues and Th2, under response to over expression of pro inflammatory cytokines stimulated the production of IL-4, IL-5, IL-6, IL-9, IL-10, and IL-13 of anti inimflammatory mytokines in evoked strong antibody responses (including those of the IgE class) and eosinophil accumulation, and inhibited several functions of phagocytic cells as indicated above.
Taken together, Lentil lectin may have a anti inflammatory effect in reduced over expression of pro inflammatory factors in initiation of symptoms of fever, headache, swelling, redness, loss of appetite, muscle stiffness through activating production of anti inflammatory mytokines.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Loose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Home page http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.
Sources
(1) Role of Th1 and Th2 Cytokines in Immune Response to Uncomplicated Plasmodium falciparum Malaria by Donato Torre,1,* Filippo Speranza,1 Massimo Giola,1 Alberto Matteelli,2 Roberto Tambini,1 andGilberto Biondi1(PMC)
(2) Dietary lectins can induce in vitro release of IL-4 and IL-13 from human basophils by Haas H1, Falcone FH, Schramm G, Haisch K, Gibbs BF, Klaucke J, Pöppelmann M, Becker WM, Gabius HJ, Schlaak M.(PubMed)
(3) T-cell subsets (Th1 versus Th2) by Romagnani S1(PubMed)
Monday, September 24, 2018
How to Normalize Your High Blood Pressure, Cholesterol and Sugar Quickly, Revealed by Researchers
Add a portion of dried peas in your daily diet will normalize the levels of High Blood Pressure, Cholesterol and Glucose, according to PubMed.
Hypertension, hyperglycemia and hyperlipidemia are most prevalent modifiable risk factors for development of diabetes, cardiovascular diseases and stroke.
Dried pea is a small but nutritionally mighty member of the legume family, genus Pisum belongings to the family Fabaceae with healthy source of proteins, fibers, vitamins and minerals.
The Nutrients and Chemical constituents
1. Carbohydrates
2. Dietary fiber
3. Fat
4. Protein
5. Vitamin A ( Beta carotene, lutein and zeaxanthin)
6. B vitamins
7. Vitamin C
8. Calcium
9. Iron
10. Magnesium
11. Phosphorus
12. Potassium
13. Zinc
14. Chemical constituents include saponin pisatin, L-pipecolic acid, glycoside-Pisatoside, tocopherols, cerebroside,....
1. The Effects of Dried Peas on High Blood Pressure
Hypertension is a chronic condition characterized by abnormal high blood pressure.
According to the Veterans' Affairs Medical Center, daily intake of fiber has emerged not only to prevent and treat various types of chronic diseases.but also reduced risk of hypertension.
Dr. Anderson JW, the led author said, "Dried beans, oat products, and certain fruits and vegetables are good sources of soluble fiber" and "Current guidelines advise a doubling of dietary fiber intake for Americans. Inclusion of ample servings of fruits and vegetables, whole grains, and dried beans and peas will help individuals meet these guidelines".
Additionally, in the examined iineralocorticoid excess-treated mice with a control diet, high-fiber diet, or acetate supplementation researcher found that high fiber diet not only modified the gut microbiota populations and also increased the abundance of acetate-producing bacteria independently of mineralocorticoid excess and reduced systolic and diastolic blood pressures.
Dr. Marques FZ, the led researcher said, "The favorable effects of fiber may be explained by the generation and distribution of one of the main metabolites of the gut microbiota, the short-chain fatty acid acetate. Acetate effected several molecular changes associated with improved cardiovascular health and function".
These result demonstrated a significant effect of fibers intake in promoted health gut microbiota in regulating molecular changes associated with improved risk factor related to cardiovascular health and function, including blood pressure.
Other, in the examined cross-sectional studies of dietary intake as one of the major determinants in hypertension development and Dietary Approach to Stop Hypertension and the risk of incident hypertension in a large cohort study including incidence of hypertension among 80 426 French adults, researchers at the joint study led by the Paris-Descartes University found that
1. During a mean follow-up of 3.4±2.1 years, 2413 cases of incident hypertension were documented
2. Fiber intake displayed a strong effect in reduced risk of hypertension with relative odd risk of 0.81 in compared to the baseline.
3. Adopting a global healthy diet associated to several nutritional factors intake may be one of the best solution in reduced hypertensive incidence.
2. The Effects of Dried Peas on High Blood Cholesterol
Hyperlipidemia is a condition characterized by high levels of cholesterol in the blood stream.
In a study of 173 women and men, with a mean body mass index of approximately 36 kg m(-2) (one-fifth with diabetes type 2) randomizedly assigned to a high-fibre bean-rich diet that achieved mean (SD) fibre intakes of 35.5 (18.6) g day for women and 42.5 (30.3) g day for men, or a low-carbohydrate diet, researchers found that
1. High bean fiber intake showed a better weight loss and weight control in compared to low carbohydrate diet group.
2. Intake of bean fiber group expressed a significant decreased of Low-density lipoprotein (LDL)-cholesterol and total cholesterol levels in compared to other group.
Dr. Tonstad S, the led author said, "A high-fibre bean-rich diet was as effective as a low-carbohydrate diet for weight loss, although only the bean-rich diet lowered atherogenic lipids".
Additionally, in dyslipidemia rats study to evaluate the effects of grain-bean package, dietary fiber (DF) extracted from grain-bean package, and DF from grain corn on the blood lipids and fatty acid synthase (FAS) activity in high-fat, high-cholesterol feeding by randomly assigned into normal control group, hyperlipidemia model group, grain-bean package group, grain-bean package DF group and grain corn group, researchers after adjusting to other risk factors filed the following results
*Rats in hyperlipidemic model group showed a increased total cholesterol (TC), triglyceridaemia (TG), high density lipoprotein cholesterol (HDL-C), fasting blood glucose (FBG) in compared to groups.
* In compared to hyperlipidemic model group, grain-bean package group, grain-bean package DF group, expressed significantly decreased total cholesterol (TC), triglyceridaemia (TG), high density lipoprotein cholesterol (HDL-C), fasting blood glucose and significantly increased HDL-C levels.
The results of these findings demonstrated that dietary fiber can improve blood lipids levels indyslipidemic subject, decrease FAS activity and regulating SREBP-1c mRNA in glucose metabolic expression.
3. The Effects of Dried Peas on High Blood Glucose
Hyperglycemia is a medical condition characterized by abnormal high levels of glucose circulated in the blood stream.
Dried peas, a good sources of protein and fiber, is one of many rich-protein recommended for vegetarian.
Together with a low glycemic index, the peas may be considered as a high-fiber foods for daily carbohydrate intake in prediabetes.
Evidences of studies showed that a low-glycemic load meal containing psyllium soluble fiber is significantly improves the breakfast postprandial glycemic, insulinemic in adults with Type 2 DM.
In the study to compare the glycemic and insulinemic responses to 3 different meals based on dried peas, potatoes, or both in patients with type 2 diabetes, intake of the pea meal expressed a significant in tine delay of the increased postprandial plasma glucose and insulin concentrations, in compared to other meal.
Since carbohydrates counting in dried peas have been disregarded, the nutrient dried peas should be included in the consumption of low-glycemic, high-fiber foods at the expense of high-glycemic, low-fiber foods for prediabetes.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Loose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Home page http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.
Sources
(1) Health benefits and practical aspects of high-fiber diets by Anderson JW1, Smith BM, Gustafson NJ.(PubMed)
(2) High-Fiber Diet and Acetate Supplementation Change the Gut Microbiota and Prevent the Development of Hypertension and Heart Failure in Hypertensive Mice by Marques FZ1, Nelson E2, Chu PY2, Horlock D2, Fiedler A2, Ziemann M2, Tan JK2, Kuruppu S2, Rajapakse NW2, El-Osta A2, Mackay CR2, Kaye DM1(PubMed)
(3) Individual and Combined Effects of Dietary Factors on Risk of Incident Hypertension: Prospective Analysis From the NutriNet-Santé Cohort by Lelong H1, Blacher J2, Baudry J1, Adriouch S1, Galan P1, Fezeu L1, Hercberg S1, Kesse-Guyot E1.(PubMed)(4) A high-fibre bean-rich diet versus a low-carbohydrate diet for obesity by Tonstad S1, Malik N, Haddad E.(PubMed)
(5) [Effect of grain-bean package, grain-bean package dietary fiber and single whole grain dietary fiber on dyslipidemia rats].[Article in Chinese] by Liu Y, Zhai C, Sun G, Zhang H, Jiang M, Zhang H, Guo J, Lan X.(PubMed)
(6) Evaluation of a high-fiber diet in hyperlipidemia: a review by Ullrich IH.(PubMed)(7) Effects of breakfast meal composition on second meal metabolic responses in adults with Type 2 diabetes mellitus by Clark CA, Gardiner J, McBurney MI, Anderson S, Weatherspoon LJ, Henry DN, Hord NG.(PubMed)
(8) Comparison of the effects of dried peas with those of potatoes in mixed meals on postprandial glucose and insulin concentrations in patients with type 2 diabetes by Schäfer G, Schenk U, Ritzel U, Ramadori G, Leonhardt U.(PubMed)
Hypertension, hyperglycemia and hyperlipidemia are most prevalent modifiable risk factors for development of diabetes, cardiovascular diseases and stroke.
Dried pea is a small but nutritionally mighty member of the legume family, genus Pisum belongings to the family Fabaceae with healthy source of proteins, fibers, vitamins and minerals.
The Nutrients and Chemical constituents
1. Carbohydrates
2. Dietary fiber
3. Fat
4. Protein
5. Vitamin A ( Beta carotene, lutein and zeaxanthin)
6. B vitamins
7. Vitamin C
8. Calcium
9. Iron
10. Magnesium
11. Phosphorus
12. Potassium
13. Zinc
14. Chemical constituents include saponin pisatin, L-pipecolic acid, glycoside-Pisatoside, tocopherols, cerebroside,....
1. The Effects of Dried Peas on High Blood Pressure
Hypertension is a chronic condition characterized by abnormal high blood pressure.
According to the Veterans' Affairs Medical Center, daily intake of fiber has emerged not only to prevent and treat various types of chronic diseases.but also reduced risk of hypertension.
Dr. Anderson JW, the led author said, "Dried beans, oat products, and certain fruits and vegetables are good sources of soluble fiber" and "Current guidelines advise a doubling of dietary fiber intake for Americans. Inclusion of ample servings of fruits and vegetables, whole grains, and dried beans and peas will help individuals meet these guidelines".
Additionally, in the examined iineralocorticoid excess-treated mice with a control diet, high-fiber diet, or acetate supplementation researcher found that high fiber diet not only modified the gut microbiota populations and also increased the abundance of acetate-producing bacteria independently of mineralocorticoid excess and reduced systolic and diastolic blood pressures.
Dr. Marques FZ, the led researcher said, "The favorable effects of fiber may be explained by the generation and distribution of one of the main metabolites of the gut microbiota, the short-chain fatty acid acetate. Acetate effected several molecular changes associated with improved cardiovascular health and function".
These result demonstrated a significant effect of fibers intake in promoted health gut microbiota in regulating molecular changes associated with improved risk factor related to cardiovascular health and function, including blood pressure.
Other, in the examined cross-sectional studies of dietary intake as one of the major determinants in hypertension development and Dietary Approach to Stop Hypertension and the risk of incident hypertension in a large cohort study including incidence of hypertension among 80 426 French adults, researchers at the joint study led by the Paris-Descartes University found that
1. During a mean follow-up of 3.4±2.1 years, 2413 cases of incident hypertension were documented
2. Fiber intake displayed a strong effect in reduced risk of hypertension with relative odd risk of 0.81 in compared to the baseline.
3. Adopting a global healthy diet associated to several nutritional factors intake may be one of the best solution in reduced hypertensive incidence.
2. The Effects of Dried Peas on High Blood Cholesterol
Hyperlipidemia is a condition characterized by high levels of cholesterol in the blood stream.
In a study of 173 women and men, with a mean body mass index of approximately 36 kg m(-2) (one-fifth with diabetes type 2) randomizedly assigned to a high-fibre bean-rich diet that achieved mean (SD) fibre intakes of 35.5 (18.6) g day for women and 42.5 (30.3) g day for men, or a low-carbohydrate diet, researchers found that
1. High bean fiber intake showed a better weight loss and weight control in compared to low carbohydrate diet group.
2. Intake of bean fiber group expressed a significant decreased of Low-density lipoprotein (LDL)-cholesterol and total cholesterol levels in compared to other group.
Dr. Tonstad S, the led author said, "A high-fibre bean-rich diet was as effective as a low-carbohydrate diet for weight loss, although only the bean-rich diet lowered atherogenic lipids".
Additionally, in dyslipidemia rats study to evaluate the effects of grain-bean package, dietary fiber (DF) extracted from grain-bean package, and DF from grain corn on the blood lipids and fatty acid synthase (FAS) activity in high-fat, high-cholesterol feeding by randomly assigned into normal control group, hyperlipidemia model group, grain-bean package group, grain-bean package DF group and grain corn group, researchers after adjusting to other risk factors filed the following results
*Rats in hyperlipidemic model group showed a increased total cholesterol (TC), triglyceridaemia (TG), high density lipoprotein cholesterol (HDL-C), fasting blood glucose (FBG) in compared to groups.
* In compared to hyperlipidemic model group, grain-bean package group, grain-bean package DF group, expressed significantly decreased total cholesterol (TC), triglyceridaemia (TG), high density lipoprotein cholesterol (HDL-C), fasting blood glucose and significantly increased HDL-C levels.
The results of these findings demonstrated that dietary fiber can improve blood lipids levels indyslipidemic subject, decrease FAS activity and regulating SREBP-1c mRNA in glucose metabolic expression.
3. The Effects of Dried Peas on High Blood Glucose
Hyperglycemia is a medical condition characterized by abnormal high levels of glucose circulated in the blood stream.
Dried peas, a good sources of protein and fiber, is one of many rich-protein recommended for vegetarian.
Together with a low glycemic index, the peas may be considered as a high-fiber foods for daily carbohydrate intake in prediabetes.
Evidences of studies showed that a low-glycemic load meal containing psyllium soluble fiber is significantly improves the breakfast postprandial glycemic, insulinemic in adults with Type 2 DM.
In the study to compare the glycemic and insulinemic responses to 3 different meals based on dried peas, potatoes, or both in patients with type 2 diabetes, intake of the pea meal expressed a significant in tine delay of the increased postprandial plasma glucose and insulin concentrations, in compared to other meal.
Since carbohydrates counting in dried peas have been disregarded, the nutrient dried peas should be included in the consumption of low-glycemic, high-fiber foods at the expense of high-glycemic, low-fiber foods for prediabetes.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Loose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Home page http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.
Sources
(1) Health benefits and practical aspects of high-fiber diets by Anderson JW1, Smith BM, Gustafson NJ.(PubMed)
(2) High-Fiber Diet and Acetate Supplementation Change the Gut Microbiota and Prevent the Development of Hypertension and Heart Failure in Hypertensive Mice by Marques FZ1, Nelson E2, Chu PY2, Horlock D2, Fiedler A2, Ziemann M2, Tan JK2, Kuruppu S2, Rajapakse NW2, El-Osta A2, Mackay CR2, Kaye DM1(PubMed)
(3) Individual and Combined Effects of Dietary Factors on Risk of Incident Hypertension: Prospective Analysis From the NutriNet-Santé Cohort by Lelong H1, Blacher J2, Baudry J1, Adriouch S1, Galan P1, Fezeu L1, Hercberg S1, Kesse-Guyot E1.(PubMed)(4) A high-fibre bean-rich diet versus a low-carbohydrate diet for obesity by Tonstad S1, Malik N, Haddad E.(PubMed)
(5) [Effect of grain-bean package, grain-bean package dietary fiber and single whole grain dietary fiber on dyslipidemia rats].[Article in Chinese] by Liu Y, Zhai C, Sun G, Zhang H, Jiang M, Zhang H, Guo J, Lan X.(PubMed)
(6) Evaluation of a high-fiber diet in hyperlipidemia: a review by Ullrich IH.(PubMed)(7) Effects of breakfast meal composition on second meal metabolic responses in adults with Type 2 diabetes mellitus by Clark CA, Gardiner J, McBurney MI, Anderson S, Weatherspoon LJ, Henry DN, Hord NG.(PubMed)
(8) Comparison of the effects of dried peas with those of potatoes in mixed meals on postprandial glucose and insulin concentrations in patients with type 2 diabetes by Schäfer G, Schenk U, Ritzel U, Ramadori G, Leonhardt U.(PubMed)
Sunday, September 23, 2018
11 Health Benefits and 3 Critical Adverse-Effects of Grape Seed Extract, According to PubMed
Grape is a woody vines of the genus Vitis, belong to the family Vitaceae, native to southern Turkey.
A. Quoted From The World Most Popular Herbs
Grape Seed Extract is the commercial extracts from whole grape seeds that contains many concentrations, including vitamin E, flavonoids, linoleic acid, oligomeric proanthocyanidins(OPCs), etc..The herb has been used in traditional medicine as antioxidant, anti-inflammatory agents and to treat skin wounds with less scarring, allergies, macular degeneration, arthritis, enhance circulation of blood vessels, lower cholesterol, etc.
A. Health Benefits
1. Ulcer
in the comparison of effects of Grape Seed Extract (GSE) and vitamins C and E on aspirin- and ethanol-induced gastric ulcer and associated increases of lipid peroxidation in rats, found that GSE protected against ethanol-induced gastric ulcers more effectively than VC or VE, while its protection against aspirin ulcers was comparable for all treatments. GSE produced the greatest reductions of gastric MDA in both models, according to" Effects of grape seed extract, vitamin C, and vitamin e on ethanol- and aspirin-induced ulcers" by Cuevas VM, Calzado YR, Guerra YP, Yera AO, Despaigne SJ, Ferreiro RM, Quintana DC.(1)
2. Pulmonary fibrosis
in assessment of grape seed extract (GSE) or vitamin E (Vit E) as antioxidants in effecting oxidative stress implication in the pathogenesis of silica-induced lung fibrosis indicated that according to the results of this study GSE could reduce the fibrogenic effect of silica. However; no synergistic effect was observed after co-administration of GSE and Vit E, according to "A comparative study of grape seed extract and vitamin E effects on silica-induced pulmonary fibrosis in rats" by Hemmati AA, Nazari Z, Samei M.(2)
3. Liver protective effect
In the observation of the efficacy of methotrexate (MTX), a widely used cytotoxic chemotherapeutic agent, and its liver protective effect found that GSE was supplemented, no significant changes in blood count parameters were noted. It appears that GSE protects the rat liver and inhibits methotrexate-induced oxidative stress. These data indicate that GSE may be of therapeutic benefit when used with MTX, according to "Role of grape seed extract on methotrexate induced oxidative stress in rat liver" by Cetin A, Kaynar L, Kocyigit I, Hacioglu SK, Saraymen R, Ozturk A, Sari I, Sagdic O.(3)
4. Antioxidant Activity
in the assessment of phenolic content, antioxidant activity of White and red wines spiked with green tea extract and grape seed extract found that the green tea extract and grape seed extract increased antioxidant activity dose-dependently and the CRTs varied considerably between the Korean and Australian groups, with Koreans preferring wines spiked with green tea extract and Australians showing a preference for wines spiked with grape seed extract, according to "Total Phenolic Content, Antioxidant Activity and Cross-Cultural Consumer Rejection Threshold in White and Red Wines Functionally Enhanced with Catechin-Rich" by Yoo YJ, Saliba A, Prenzler PD, Ryan DM.(4)
5. Skin Photoprotection
In the study of polyphenols distributed in plant foods, such as, fruits, vegetables, nuts, flowers, bark and seeds, etc., found that the selected polyphenols include: green tea polyphenols, pomegranate fruit extract, grape seed proanthocyanidins, resveratrol, silymarin, genistein and delphinidin. The new information on the mechanisms of action of these polyphenols supports their potential use in skin photoprotection and prevention of photocarcinogenesis in humans, according to "Polyphenols: Skin Photoprotection and Inhibition of Photocarcinogenesis" by Afaq F, Katiyar SK.(5)
6. Renal Ischemia/Reperfusion Injuries
In the evaluation of grape seed proanthocyanidin extract (GSPE) protects against renal I/R injury found that GSPE significantly reduced increases in urea, creatinine and cystatin C; increased kidney superoxide dismutase activity and glutathione peroxidase levels and reduced malondialdehyde levels. GSPE reduced histological renal damage and nuclear factor-κB activity. These results suggest that GSPE reduces renal dysfunction and injury caused by renal I/R, according to "Grape Seed Proanthocyanidin Extract Reduces Renal Ischemia/Reperfusion Injuries in Rats" by Wei R, Ding R, Wang Y, Tang L.(6)
7. Anticancers
a. In the reviews of Grapes and grape-based products as one such class of dietary products and its cancer chemopreventive potential, indicated that Overall, completed studies from various scientific groups conclude that both grapes and grape-based products are excellent sources of various anticancer agents and their regular consumption should thus be beneficial to the general population, according to "Anticancer and cancerchemopreventive potential of grape seed extract and other grape-based products" by Kaur M, Agarwal C, Agarwal R.(7a)
b. In the study of the biological and chemopreventive activities of grapeseed polyphenols and its inhibition of either initiation or promotion/progression stages of carcinogenesis found that suggest that the chemopreventive activity of polyphenols extracted from seedless grapecultivars was as effective as that of the seeded variety and these may have beneficial effects in disease states, especially cancer, according to "Antitumor-promoting effects of polyphenolic extracts from seedless and seeded Indian grapes" by Ramchandani AG, Karibasappa GS, Pakhale SS.(7b)
8. Colon Cancer
In the investigation of polyphenols of grape waste and its protection against human diseases related to oxidative stress, such as colorectal cancer, found that the grape extract has a significant antiproliferative effect in a tumor cell line. These data indicate that grape extract is a promising product to be used as an anti-free radical agent and could exert a chemopreventive action, according to "Grape waste extract obtained by supercritical fluid extraction contains bioactive antioxidant molecules and induces antiproliferative effects in human colon adenocarcinoma cells" byLazzè MC, Pizzala R, Gutiérrez Pecharromán FJ, Gatòn Garnica P, Antolín Rodríguez JM, Fabris N, Bianchi L.(8)
9. Prostate cancer
In the analyzing the bioflavonoids from Grape seed extract (GSE) and theirs effect on prostate cancer (PCA) found that that GSE possibly causes mitochondrial damage leading to cytochrome c release in cytosol and activation of caspases resulting in PARP cleavage and execution of apoptotic death of human PCA DU145 cells. Furthermore, GSE-caused caspase 3-mediated apoptosis also involves other pathway(s) including caspase 9 activation, according to "Grape seed extract induces apoptotic death of human prostate carcinoma DU145 cells via caspases activation accompanied by dissipation of mitochondrial membrane potential and cytochrome c release" by Agarwal C, Singh RP, Agarwal R.(9)
10. Atherosclerosis
in the association of consumption of red wine and other polyphenolic compounds and prevention of cardiovascular diseases found that aortic atherosclerosis evaluated as the cholesterol content in aortic tissue was comparable in the control and GSE-dosed females, but it was significantly reduced in the abdominal part of GSE-dosed male compared to the controls (P < 0.05). In conclusion, feeding GSE extract to Watanabe heritable hyperlipidemic (WHHL) rabbits had no significant effects in females but was associated with transient less hypercholesterolemic response to semisynthetic diet, according to "Effects of red grape skinand seed extract supplementation on atherosclerosis in Watanabe heritable hyperlipidemic rabbits" by Frederiksen H, Mortensen A, Schrøder M, Frandsen H, Bysted A, Knuthsen P, Rasmussen SE.(10)
11. Arthritis (CIA)
in the examination of whether grape seed proanthocyanidin extract (GSPE) effect on collagen-induced arthritis (CIA) in mice found that GSPE dose-dependently suppressed osteoclastogenesis in vitro. GSPE significantly reduced hydrogen peroxide production by anti-CD3-monoclonal-antibody-stimulated CD4+ splenocytes. These results indicate that intraperitoneal injection of GSPE attenuated CIA in mice. GSPE may be useful in the treatment of rheumatoid arthritis, according to "Grapeseed proanthocyanidin extract (GSPE) attenuates collagen-induced arthritis" by Cho ML, Heo YJ, Park MK, Oh HJ, Park JS, Woo YJ, Ju JH, Park SH, Kim HY, Min JK.(11).
B. Side Effects
1. Digestive discomforts, such as recurrent nausea, vomiting, diarrhea, and acute weakness(12)
2. Grape seed extract may induce a decrease in the concentrations of plasma copper, iron and zinc(13)
3. Intake of the extract may cause imbalance of intestinal microflora and interference with gut morphology(14)
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Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.
Sources
(1) http://www.ncbi.nlm.nih.gov/pubmed/22162675
(2) http://www.ncbi.nlm.nih.gov/pubmed/18547852
(3) http://www.ncbi.nlm.nih.gov/pubmed/19051353
(4) http://www.ncbi.nlm.nih.gov/pubmed/22133028
(5) http://www.ncbi.nlm.nih.gov/pubmed/22070679
(6) http://www.ncbi.nlm.nih.gov/pubmed/22157385
(7a) http://www.ncbi.nlm.nih.gov/pubmed/19640973
(7b) http://www.ncbi.nlm.nih.gov/pubmed/19105538
(8) http://www.ncbi.nlm.nih.gov/pubmed/19627204
(9) http://www.ncbi.nlm.nih.gov/pubmed/12419835
(10) http://www.ncbi.nlm.nih.gov/pubmed/17441214
(11) http://www.ncbi.nlm.nih.gov/pubmed/19446580
(12) https://www.ncbi.nlm.nih.gov/pubmed/25688637
(13) https://www.ncbi.nlm.nih.gov/pubmed/23031407
(14) https://www.ncbi.nlm.nih.gov/pubmed/21325227
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