Scientists may have found a whole herb which processes anti-diabetes property, some scientists suggested.
Diabetes is a chronic condition characterized by insufficient insulin entering the bloodstream to regulate the glucose as a result of either cell in pancreas dying off or receptor sites clogged up by fat and cholesterol.
In some cases, diabetes may also be caused by allergic reactions of cells in the immune system.
The actual causes of diabetes inflammatory condition are debatable.
Some researchers also do not know why some people without genetic mutations are susceptible to type 2 diabetes while others do not.
However, certain risk factors such as overweight and obesity (overexpression of fatty tissue that causes insulin resistant), physical inactivity, family history, race,,,,, and age. ...
Women developed gestational diabetes, polycystic ovary syndrome,.... and high blood pressure is also some major risk factors associated to increase the risk of type 2 diabetes.
The first line medicine used for the treatment of type 2 diabetes is metformin which processes a significant effect in improving the body tissue sensitivity to insulin. In other words, metformin improves the body uses insulin more effectively. and lowers glucose production in the liver.
In the stage prediabetes, patients may not experience any symptoms. However, untreated diabetes or diabetes that do not manage properly, may increase the risk of cataracts and glaucoma, foot damage.
In advance stage, untreated diabetes can also cause nerve damage or poor blood flow to the feet which in turn, increases the risk of various foot complications.
Alfalfa is a flowering plant in the genus Medicago, belonging to the family Fabaceae, It has been cultivated all over the world as hay for cattle feeding.
The leaves, sprouts, and seeds to make medicine has been used in traditional medicine over thousands of year to treat high cholesterol, asthma, osteoarthritis, rheumatoid arthritis, diabetes, enhance digestive system, bleeding disorder, kidney, and urinary tract infection, etc. North America aboriginal has used Alfalfa seed as food, such as making bread and mush.
Ingredients
1. Essential amino acids
2. Calcium
3. Magnesium
4. Potassium
5. Iron
6. Phosphorus
7. Zinc
8. Beta carotene
9. vitamin C
10. vitamins D
11.Vitamin E
12. Vitamin K
It chemical constituents include flavones, isoflavones, sterols, Bichanin, Coumestrol, Diadzein, Formonetin, Genistein,.... and coumarin derivatives.
In the study to examine the Lucerne (alfalfa) effect by oral administrated the herbal extract through diet (62.5 g/kg) and drinking water (2.5 g/l) in reducing the hyperglycemia of streptozotocin-diabetic mice, researchers found
* Application of aqueous extract of lucerne exerts a significant stimulation of insulin secretion from the pancreatic B-cell line.
* Application of aqueous extract of lucern also promotes insulin-like activity in inhibited overexpression glucose.
* The sequential extraction with solvents revealed .higher insulin-releasing activity in both methanol and water fractions compared to one extract constituent.
Further analysis also suggested that the activity of the extract was found to be heat stable and enhanced by exposure to acid and alkali (0.1 M-HCl and NaOH).
Dr. Gray AM, the lead author at the final report wrote, "The results demonstrate the presence of antihyperglycaemic, insulin-releasing and insulin-like activity in the traditional antidiabetic plant, Medicago sativa".
Additionally, in the study to reaffirm the effect herbal alfalfa against onset of diabetes researchers launched a study to compare alfalfa with other herbal medicine including dried leaves of agrimony (Agrimonia eupatoria), blackberry (Rubus fructicosus), celandine (Chelidonium majus), eucalyptus (Eucalyptus globulus), lady's mantle (Alchemilla vulgaris), and lily of the valley (Convallaria majalis); seeds of coriander (Coriandrum sativum); dried berries of juniper (Juniperus communis); bulbs of garlic (Allium sativum) and roots of liquorice (Glycyrhizza glabra).
In mice administrated by streptozotocin (200 mg/kg i.p.) to induce the development of hyperphagia, polydipsia, body weight loss, hyperglycemia and hypoinsulinemia, researchers found that
* Herbal alfalfa exerts a strong effect in reduced the level of hyperglycemia during the development of streptozotocin diabetes compared to others herbs.
* Herbal alfalfa reduced polydipsia and a reduced rate of body weight loss.
* Alfalfa initially countered the hyperinsulinaemic effect of streptozotocin, without affecting the fall in plasma insulin.
Dr. said, after taking into account of other co and confounders, " The results suggest that certain traditional plant treatments for diabetes, namely alfalfa,.......can retard the development of streptozotocin diabetes in mice".
Taking all together, herbal alfalfa may be considered a functional herb for the prevention and treatment of type 2 diabetes.
However, additional data collection on large example size and multi-center clinical studies performed with human consumption of the whole food during the course of the disease will be necessary to complete the picture of alfalfa anti-type 2 diabetes possibilities.
And long-term multiple dietary supplement consumption of a broad array of vitamin/mineral, herbal, and condition-specific dietary supplements on a daily basis should consult with their doctors or related field specialist before applying.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton, Master of Nutrition
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
References
(1) Pancreatic and extra-pancreatic effects of the traditional anti-diabetic plant, Medicago sativa (lucerne) by Gray AM, Flatt PR. (PubMed)
(2) Traditional plant treatments for diabetes. Studies in normal and streptozotocin diabetic mice. by Swanston-Flatt SK, Day C, Bailey CJ, Flatt PR. (PubMed)
(3) Drug-induced lupus: an update by Vasoo S.(PubMed)
Monday, December 31, 2018
Sunday, December 30, 2018
The Anti Cancers Night Shade Vegetable, Scientists show
Eggplant, the nightshade vegetable may be considered a functional food for the prevention and treatment of cancers, some researchers suggested.
Cancers are class of chronic diseases caused alternation of DNA of healthy cells.
In other words, healthy cells become cancerous if they grow uncontrollably and disorderly out of range of a normal healthy cell population which can only divide between 40 and 60 times.
According to the Hayflick limit theory, most cells survival is totally dependent on the telomeres on the ends of each chromosome.
Every time, healthy cells undergo division, the telomeres are shortened. Once the telomeres shorten to a critical length, the cells will die off.
In advance stage, traveling through fluid and blood circulation, most invasive cancer cells can infect healthy cells or tissue a distance away from the originated site.
According to the statistic provided the Canadian Health Service, In 2017, over 200,000 Canadians will be diagnosed with cancer and 80,000 will die from cancer.
Sadly, 1 in 2 Canadians will be diagnosed with cancer during their lifetime and 1 in 4 will die from the disease.
Lung, colorectal, breast and prostate cancers are the most common cancer found in Canadian, accounting for half of all cancers diagnosed.
And 60% of Canadians diagnosed with cancer will survive at least 5 years after their diagnosis.
Eggplant is a species of S. melongena, belonging to the family Solanaceae and native to India.
The plant has been cultivated in southern and eastern Asia since prehistory.
Eggplant is famous with its deep purple and the best eggplant can be found from August through October when it is in season.
Nutritional Supplements
1. Carbohydrates
2. Sugars
3. Fiber
4. Fat
5. Protein
6. Thiamine (Vitamin B1)
7. Riboflavin (Vitamin B2)
8. Niacin (Vitamin B3)
9. Pantothenic acid (B5)
10. Vitamin B6
11. Folate (Vitamin B9)
12. Vitamin C
13. Tryptophan
14. Manganese
15. Calcium
16. Copper
17. Iron
18. Magnesium
19. Phosphorus
20. Potassium
21. Zinc
Chemical constituents
The vegetable chemical compounds containing include sterols (i.e. typical plant sterols, androstane, pregnane and cholestane derivatives, steroidal alkaloids, and sapogenins), phytosterols, triterpenes, δ-amyrin, Chlorogenic acid, Nasunin, and other Polyphenolic compounds.
In the effort to find the plant-derived foods such as potatoes, eggplants, and tomatoes with potential antiproliferative activities against human colon (HT29) and liver (HepG2) cancer cells, researchers at the Yeungnam University conducted a study to evaluate series of structurally related individual compounds in these plants, using microculture tetrazolium (MTT) assay.
Glycoalkaloids solamargine and solasonine and their common aglycon solasodine; and the nonsteroidal alkaloid jervine isolated from eggplant were selected to test the anti cancers possibilities compared to other compound isolated from potatoes and tomatoes.
After taking into account other factors, researchers found that
* Glycoalkaloids derived from eggplant exerts the most active anticancer cells compared to others. However, its hydrolysis products are less active compared to glycoalkaloids.
* Compounds isolated from eggplant are very effective against the liver cancer cells compared to colon cancer cells.
Dr. Lee KR, the lead author on the final report said, "....safety considerations should guide the use of these compounds preventative or therapeutic treatments against carcinomas".
Furthermore, the study to investigate the inhibitory effect of eggplant (Solanum melongena var. marunasu) extract on the human fibrosarcoma HT-1080 cell invasion of reconstituted basement membrane [Matrigel (MG)], researchers discovered
* Delphinidin, a flavonoid pigment contained in the peel demonstrates the most effective against human fibrosarcoma HT-1080 cell.
* Interestingly, application of eggplant extract and delphinidin did not affect tumor cell adhesion to MG or haptotactic migration to MG.
Further analysis of these effects, researchers found that the inhibition of cancer was attributed to
delphinidin of blocking the activity of Matrix metalloproteinases MMPs which are responsible for the degradation of most extracellular matrix proteins during organogenesis, growth and normal tissue turnover.
The findings suggested that the frequency of eggplant intake may associate to reduce the risk of cancers. However, further data collection on large example size and multi-center studies performed with human consumption of the whole food eggplant during the course of cancer will be necessary to complete the picture of eggplant and its bioactive ingredients anti-cancer possibilities.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton, Master of Nutrition
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
References
(1) Glycoalkaloids and metabolites inhibit the growth of human colon (HT29) and liver (HepG2) cancer cells by Lee KR1, Kozukue N, Han JS, Park JH, Chang EY, Baek EJ, Chang JS, Friedman M.(PubMed)
(2) Inhibitory effect of delphinidin from Solanum melongena on human fibrosarcoma HT-1080 invasiveness in vitro by Nagase H1, Sasaki K, Kito H, Haga A, Sato T.(PubMed)
Cancers are class of chronic diseases caused alternation of DNA of healthy cells.
In other words, healthy cells become cancerous if they grow uncontrollably and disorderly out of range of a normal healthy cell population which can only divide between 40 and 60 times.
According to the Hayflick limit theory, most cells survival is totally dependent on the telomeres on the ends of each chromosome.
Every time, healthy cells undergo division, the telomeres are shortened. Once the telomeres shorten to a critical length, the cells will die off.
In advance stage, traveling through fluid and blood circulation, most invasive cancer cells can infect healthy cells or tissue a distance away from the originated site.
According to the statistic provided the Canadian Health Service, In 2017, over 200,000 Canadians will be diagnosed with cancer and 80,000 will die from cancer.
Sadly, 1 in 2 Canadians will be diagnosed with cancer during their lifetime and 1 in 4 will die from the disease.
Lung, colorectal, breast and prostate cancers are the most common cancer found in Canadian, accounting for half of all cancers diagnosed.
And 60% of Canadians diagnosed with cancer will survive at least 5 years after their diagnosis.
Eggplant is a species of S. melongena, belonging to the family Solanaceae and native to India.
The plant has been cultivated in southern and eastern Asia since prehistory.
Eggplant is famous with its deep purple and the best eggplant can be found from August through October when it is in season.
Nutritional Supplements
1. Carbohydrates
2. Sugars
3. Fiber
4. Fat
5. Protein
6. Thiamine (Vitamin B1)
7. Riboflavin (Vitamin B2)
8. Niacin (Vitamin B3)
9. Pantothenic acid (B5)
10. Vitamin B6
11. Folate (Vitamin B9)
12. Vitamin C
13. Tryptophan
14. Manganese
15. Calcium
16. Copper
17. Iron
18. Magnesium
19. Phosphorus
20. Potassium
21. Zinc
Chemical constituents
The vegetable chemical compounds containing include sterols (i.e. typical plant sterols, androstane, pregnane and cholestane derivatives, steroidal alkaloids, and sapogenins), phytosterols, triterpenes, δ-amyrin, Chlorogenic acid, Nasunin, and other Polyphenolic compounds.
In the effort to find the plant-derived foods such as potatoes, eggplants, and tomatoes with potential antiproliferative activities against human colon (HT29) and liver (HepG2) cancer cells, researchers at the Yeungnam University conducted a study to evaluate series of structurally related individual compounds in these plants, using microculture tetrazolium (MTT) assay.
Glycoalkaloids solamargine and solasonine and their common aglycon solasodine; and the nonsteroidal alkaloid jervine isolated from eggplant were selected to test the anti cancers possibilities compared to other compound isolated from potatoes and tomatoes.
After taking into account other factors, researchers found that
* Glycoalkaloids derived from eggplant exerts the most active anticancer cells compared to others. However, its hydrolysis products are less active compared to glycoalkaloids.
* Compounds isolated from eggplant are very effective against the liver cancer cells compared to colon cancer cells.
Dr. Lee KR, the lead author on the final report said, "....safety considerations should guide the use of these compounds preventative or therapeutic treatments against carcinomas".
Furthermore, the study to investigate the inhibitory effect of eggplant (Solanum melongena var. marunasu) extract on the human fibrosarcoma HT-1080 cell invasion of reconstituted basement membrane [Matrigel (MG)], researchers discovered
* Delphinidin, a flavonoid pigment contained in the peel demonstrates the most effective against human fibrosarcoma HT-1080 cell.
* Interestingly, application of eggplant extract and delphinidin did not affect tumor cell adhesion to MG or haptotactic migration to MG.
Further analysis of these effects, researchers found that the inhibition of cancer was attributed to
delphinidin of blocking the activity of Matrix metalloproteinases MMPs which are responsible for the degradation of most extracellular matrix proteins during organogenesis, growth and normal tissue turnover.
The findings suggested that the frequency of eggplant intake may associate to reduce the risk of cancers. However, further data collection on large example size and multi-center studies performed with human consumption of the whole food eggplant during the course of cancer will be necessary to complete the picture of eggplant and its bioactive ingredients anti-cancer possibilities.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton, Master of Nutrition
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
References
(1) Glycoalkaloids and metabolites inhibit the growth of human colon (HT29) and liver (HepG2) cancer cells by Lee KR1, Kozukue N, Han JS, Park JH, Chang EY, Baek EJ, Chang JS, Friedman M.(PubMed)
(2) Inhibitory effect of delphinidin from Solanum melongena on human fibrosarcoma HT-1080 invasiveness in vitro by Nagase H1, Sasaki K, Kito H, Haga A, Sato T.(PubMed)
Friday, December 28, 2018
Green Tea, The Beverage Which Blocks The Onset of Ulcerative Colitis, Researchers Find
Green tea may have a therapeutic and positive effect for prevention and treatment of Ulcerative Colitis, some scientists suggested.
Ulcerative Colitis is a digestive condition characterized by inflammatory bowel disease (IBD) that induces chronic inflammation and ulcers (sores) in the digestive tract.
According to statistic, approximately, between 250,000 and 500,000 people are infected by ulcerative colitis in the United States. The risk of ulcerative colitis onset is between 2 to 7 per 100,000 persons.
Most common symptoms are abdominal pain and diarrhea. However, some patients may also experience symptoms of fatigue or tiredness, loss of appetite, dehydration feeling the urge to empty the bowels constantly,.... and weight loss.
If you have some of the symptoms of above, please check with your doctor to rule out the possibility of ulcerative colitis.
Researchers do not know the exact cause of Ulcerative Colitis.
Neither they know why ulcerative colitis induces chronic inflammation and ulcers (sores) in the digestive tract.
However, they do know that certain risk factors are associated to the development of the disease, including genetic mutation of a certain gene, environmental toxins, overreaction of the immune system,.... and long-term high levels of linoleic acid intake.
Green tea, a precious drink processes numbers of health benefit known to almost everyone in Asia and Western world.
As yin in nature, long-term injection of large amounts may obstruct the balance of yin-yang, induced "yin excessive syndrome" or "yang vacuity syndrome" including weaken immunity and painful case of GERD,... according to traditional Chinese medicine's Yin-Yang theory.
Mild to moderate ulcerative colitis (UC) patients, 15 received 400 mg or 800 mg of total Polyphenon E daily, administered in split doses or and 4 in placebo in a double-blinded, placebo-controlled pilot study, researchers at the end of the experiential indicated that oral administration of the extracts exerts a potential effect of reduced levels of inflammation through the improvement of the reading of the mean UC disease activity index score compared to the entry score.
After 56 days of therapy, Polyphenon E treatment group exhibited strong improvement of over response rate of 66.7% (10 of 15) and remission rate of 53.3% (8/15) compared to 0% (0/4) in both response rate and remission rate in the placebo group.
Dr. Dryden GW, the lead author, after taking into account of other co-founder said, "Administration of Polyphenon E resulted in a therapeutic benefit for(ulcerative colitis (UC)) patients who were refractory to 5-aminosalicylic and/or azathioprine".
Polyphenon E is high-quality tea catechin extracted from natural tea leaves.
Further analysis of green tea bioactive polyphenols, epigallocatechin gallate (EGCG) on dextran sulfate sodium- (DSS-) induced ulcerative colitis in rats and to explore the roles of TLR4/MyD88/NF-κB signaling pathway, indicated that application of the extract significantly improves the intestinal mucosal injury in rats though inhibited production of inflammatory factors which were overexpression during the acute phase of injuring and damage to induced further damage to the tissue.
Moreover, green tea bioactive polyphenols, epigallocatechin gallate (EGCG) also reduced chronic inflammation and maintained the balance of the ratio of Th1/Th2 T-helper (Th) lymphocytes that prevent alterations in cellular immunity in patients with ulcerative colitis.
Imbalance of Th1/Th2 was found to associate to the occurrence and development of ulcerative colitis.
Additionally, injection of green tea EGCG also reduced the levels of TLR4 signaling in activated the intracellular signaling pathway NF-κB and inflammatory cytokine production to imitate inflammation.
Amazingly, researchers also found that injection of TLR4 antagonism not only shows a significantly reduced the protective effect of EGCG on intestinal mucosal injury colitis but also increased the expressions of inflammatory factors in the production of pro-inflammatory cytokines.
Moreover, in the examine the antioxidant activity of green tea catechins in model of colitis induced by 2.4.6 trinitrobenzene sulfonic acid (TNBS) using 35 young adult Sprague-Dawley rats which are divided into four groups: normal control (n=5), catechins (n=9), TNBS (n=9) and 2.4.6 trinitrobenzene sulfonic acid (TNBS) plus catechins (n=12), at the end of the experiment researchers at the Joint study, American University of Beirut, found that groups with TNBS and catechin express strong anti-inflammatory and anti-oxidant effects of amelioration of symptoms and expression of ulcerative colitis through stabilizing the mast cells production, induced by injection of TNBS in compared to TNBS treated group.
Dr. the lead authors in the joint study suggested that the study depicted a significant amelioration in the TNBS- and EGCG-treated rats compared to the non-treated animals in similar to histological data, as the mechanism of action occurred basically through the NF-kB pathway and possibly through crosstalk with other pathways.
Taken together, green tea and its bioactive polyphenols may be considered as functional foods for the prevention and treatment of ulcerative colitis through the expression of antioxidant and anti-inflammatory activity.
Intake of green tea extract should be taken with extreme care as acute toxicity has been reported in some cases.
https://kylejnorton.blogspot.com/2018/09/green-tea-beverage-which-blocks-onset.html
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299
Sources
(1) A pilot study to evaluate the safety and efficacy of an oral dose of (-)-epigallocatechin-3-gallate-rich polyphenon E in patients with mild to moderate ulcerative colitis by Dryden GW1, Lam A, Beatty K, Qazzaz HH, McClain CJ. (PubMed)
(2) Tea catechins induce crosstalk between signaling pathways and stabilize mast cells in ulcerative colitis by Gerges Geagea A1,2, Rizzo M2, Eid A1, Hajj Hussein I3, Zgheib Z1, Zeenny MN1, Jurjus R4, Uzzo ML5, Spatola GF5, Bonaventura G5, Leone A5, Massaad-Massade L6,7,8, Jurjus A1.(PubMed)
(3) EGCG Maintains Th1/Th2 Balance and Mitigates Ulcerative Colitis Induced by Dextran Sulfate Sodium through TLR4/MyD88/NF-κB Signaling Pathway in Rats by TNBS,1 Liu Xuelei,2 Dong Wanwei,3 Liang Linlang,1 and Chen Keyan3(Hindawi)
Ulcerative Colitis is a digestive condition characterized by inflammatory bowel disease (IBD) that induces chronic inflammation and ulcers (sores) in the digestive tract.
According to statistic, approximately, between 250,000 and 500,000 people are infected by ulcerative colitis in the United States. The risk of ulcerative colitis onset is between 2 to 7 per 100,000 persons.
Most common symptoms are abdominal pain and diarrhea. However, some patients may also experience symptoms of fatigue or tiredness, loss of appetite, dehydration feeling the urge to empty the bowels constantly,.... and weight loss.
If you have some of the symptoms of above, please check with your doctor to rule out the possibility of ulcerative colitis.
Researchers do not know the exact cause of Ulcerative Colitis.
Neither they know why ulcerative colitis induces chronic inflammation and ulcers (sores) in the digestive tract.
However, they do know that certain risk factors are associated to the development of the disease, including genetic mutation of a certain gene, environmental toxins, overreaction of the immune system,.... and long-term high levels of linoleic acid intake.
Green tea, a precious drink processes numbers of health benefit known to almost everyone in Asia and Western world.
As yin in nature, long-term injection of large amounts may obstruct the balance of yin-yang, induced "yin excessive syndrome" or "yang vacuity syndrome" including weaken immunity and painful case of GERD,... according to traditional Chinese medicine's Yin-Yang theory.
Mild to moderate ulcerative colitis (UC) patients, 15 received 400 mg or 800 mg of total Polyphenon E daily, administered in split doses or and 4 in placebo in a double-blinded, placebo-controlled pilot study, researchers at the end of the experiential indicated that oral administration of the extracts exerts a potential effect of reduced levels of inflammation through the improvement of the reading of the mean UC disease activity index score compared to the entry score.
After 56 days of therapy, Polyphenon E treatment group exhibited strong improvement of over response rate of 66.7% (10 of 15) and remission rate of 53.3% (8/15) compared to 0% (0/4) in both response rate and remission rate in the placebo group.
Dr. Dryden GW, the lead author, after taking into account of other co-founder said, "Administration of Polyphenon E resulted in a therapeutic benefit for(ulcerative colitis (UC)) patients who were refractory to 5-aminosalicylic and/or azathioprine".
Polyphenon E is high-quality tea catechin extracted from natural tea leaves.
Further analysis of green tea bioactive polyphenols, epigallocatechin gallate (EGCG) on dextran sulfate sodium- (DSS-) induced ulcerative colitis in rats and to explore the roles of TLR4/MyD88/NF-κB signaling pathway, indicated that application of the extract significantly improves the intestinal mucosal injury in rats though inhibited production of inflammatory factors which were overexpression during the acute phase of injuring and damage to induced further damage to the tissue.
Moreover, green tea bioactive polyphenols, epigallocatechin gallate (EGCG) also reduced chronic inflammation and maintained the balance of the ratio of Th1/Th2 T-helper (Th) lymphocytes that prevent alterations in cellular immunity in patients with ulcerative colitis.
Imbalance of Th1/Th2 was found to associate to the occurrence and development of ulcerative colitis.
Additionally, injection of green tea EGCG also reduced the levels of TLR4 signaling in activated the intracellular signaling pathway NF-κB and inflammatory cytokine production to imitate inflammation.
Amazingly, researchers also found that injection of TLR4 antagonism not only shows a significantly reduced the protective effect of EGCG on intestinal mucosal injury colitis but also increased the expressions of inflammatory factors in the production of pro-inflammatory cytokines.
Moreover, in the examine the antioxidant activity of green tea catechins in model of colitis induced by 2.4.6 trinitrobenzene sulfonic acid (TNBS) using 35 young adult Sprague-Dawley rats which are divided into four groups: normal control (n=5), catechins (n=9), TNBS (n=9) and 2.4.6 trinitrobenzene sulfonic acid (TNBS) plus catechins (n=12), at the end of the experiment researchers at the Joint study, American University of Beirut, found that groups with TNBS and catechin express strong anti-inflammatory and anti-oxidant effects of amelioration of symptoms and expression of ulcerative colitis through stabilizing the mast cells production, induced by injection of TNBS in compared to TNBS treated group.
Dr. the lead authors in the joint study suggested that the study depicted a significant amelioration in the TNBS- and EGCG-treated rats compared to the non-treated animals in similar to histological data, as the mechanism of action occurred basically through the NF-kB pathway and possibly through crosstalk with other pathways.
Taken together, green tea and its bioactive polyphenols may be considered as functional foods for the prevention and treatment of ulcerative colitis through the expression of antioxidant and anti-inflammatory activity.
Intake of green tea extract should be taken with extreme care as acute toxicity has been reported in some cases.
https://kylejnorton.blogspot.com/2018/09/green-tea-beverage-which-blocks-onset.html
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299
Sources
(1) A pilot study to evaluate the safety and efficacy of an oral dose of (-)-epigallocatechin-3-gallate-rich polyphenon E in patients with mild to moderate ulcerative colitis by Dryden GW1, Lam A, Beatty K, Qazzaz HH, McClain CJ. (PubMed)
(2) Tea catechins induce crosstalk between signaling pathways and stabilize mast cells in ulcerative colitis by Gerges Geagea A1,2, Rizzo M2, Eid A1, Hajj Hussein I3, Zgheib Z1, Zeenny MN1, Jurjus R4, Uzzo ML5, Spatola GF5, Bonaventura G5, Leone A5, Massaad-Massade L6,7,8, Jurjus A1.(PubMed)
(3) EGCG Maintains Th1/Th2 Balance and Mitigates Ulcerative Colitis Induced by Dextran Sulfate Sodium through TLR4/MyD88/NF-κB Signaling Pathway in Rats by TNBS,1 Liu Xuelei,2 Dong Wanwei,3 Liang Linlang,1 and Chen Keyan3(Hindawi)
Thursday, December 27, 2018
Long Term Yoga Practice Improves Cognitive Function of Patients with Schizophrenia
Epidemiological studies do agree that yoga lesson may reduce symptoms and complications expression in patients with Schizophrenia, a renowned university study suggested.
Schizophrenia is a mental disorder induced inconsistent or contradictory elements such as the breakdown of certain relation in thought, emotion, and behavior, leading to faulty perception, inappropriate actions,.... and feelings.
The exact causes of schizophrenia are unknown. However, the National Health service suggested that certain risk factors involving physical, genetic, psychological and environmental circumstances are associated with the likeliness of a person to develop the condition.
Sadly, researchers do not know, why people with the same health condition, some are susceptible to Schizophrenia development the while others do not.
Furthermore, stressful or emotional life event might trigger a psychotic episode in patients with Schizophrenia.
Yoga, the accident technique practice for harmonized external and internal body well being, through breath control, meditation, bodily movement, and gesture..... has been well known for people in the Western world and some parts in Asia due to health benefits reported by various respectable institutes' research and supported by health advocates.
In the clinically stable, adult outpatients with SZ (n=286) completed baseline assessments randomized to treatment as usual (TAU), supervised yoga training with TAU (YT) or supervised physical exercise training with TAU (PE) researchers at the joint study led by the University of Pittsburgh filed the following results
* After six months and follow up, yoga showed a significant improvement of speed index of attention domain compared to control groups.
* In cognitive domains, yoga group demonstrated a significant improvement compared to PE and with TAU alone, respectively
The further assessment also suggested that both YT and PE improved attention and additional cognitive domains well past the training period, but only the YT group showed a beneficial effect of on speed index of attention domain.
These results of improvement may be attributed to the repeated practice of attentional focus and redirecting attention may be a possible active ingredient for developing greater attentional control
Moreover, the physical and cognitive benefits associated with yoga and mindfulness may be due to mechanisms that activated the parasympathetic nervous system through meditative or contemplative practices.
Some researchers also suggested long-term yoga practice increases body perception, stronger functional connectivity within the basal ganglia and increased activation of grey matter volume and amygdala with regional enlargement.
Additionally, in the review literature published in the databases of MEDLINE, PubMed, Embase, CINAHL, BIOS, AMED, PsychINFO involved randomised controlled trials (RCTs) including people with schizophrenia comparing yoga as a package of care with standard-care control, researchers found only 3 studies with all outcomes were short-term (less than eight weeks) with none of them displayed a significant change of yoga group in compared to control.
The findings indicated that short-term yoga practice may have a little effect of improvement of cognitive function.
More importantly, in patients perspective, a study of total of 100 schizophrenia patients (male: female = 57:43; age: 35.8 ± 9.2 years) attending the psychiatry out-patient services of a tertiary neuropsychiatry hospital administered a survey questionnaire, researchers at the National Institute of Mental Health and Neuro Sciences reported the following results
* 46% participant was aware that yoga is also one of the complementary therapies useful in schizophrenia.
* 32% had tried yoga in the past for some reasons, but only 31% of them were continuing yoga with reasons of lack of motivation (31%) and inability to spare time (27.6%).
* However, the majority (88.5%) of them were willing to take up add-on yoga therapy on out-patient basis along with their regular medical follow-up.
Taking all together, long-term yoga lesson may be used as a secondary and therapeutic enhancement of cognitive function in patients with schizophrenia.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton, Master of Nutrition
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Yoga as part of a package of care versus standard care for schizophrenia by Broderick J1, Vancampfort D.(PubMed)
(2) A randomized controlled trial of adjunctive yoga and adjunctive physical exercise training for cognitive dysfunction in schizophrenia by Bhatia T1, Mazumdar S2, Wood J3, He F2, Gur RE4, Gur RC4, Nimgaonkar VL5, Deshpande SN6.(PubMed)
(3) Yoga for schizophrenia: Patients' perspective by Govindaraj R1, Varambally S1, Gangadhar BN1.(PubMed)
(4) Effects of weekly one-hour Hatha yoga therapy on resilience and stress levels in patients with schizophrenia-spectrum disorders: an eight-week randomized controlled trial by Ikai S1, Suzuki T, Uchida H, Saruta J, Tsukinoki K, Fujii Y, Mimura M.(PubMed)
(5) A yoga program for cognitive enhancement by (PMC)
Schizophrenia is a mental disorder induced inconsistent or contradictory elements such as the breakdown of certain relation in thought, emotion, and behavior, leading to faulty perception, inappropriate actions,.... and feelings.
The exact causes of schizophrenia are unknown. However, the National Health service suggested that certain risk factors involving physical, genetic, psychological and environmental circumstances are associated with the likeliness of a person to develop the condition.
Sadly, researchers do not know, why people with the same health condition, some are susceptible to Schizophrenia development the while others do not.
Furthermore, stressful or emotional life event might trigger a psychotic episode in patients with Schizophrenia.
Yoga, the accident technique practice for harmonized external and internal body well being, through breath control, meditation, bodily movement, and gesture..... has been well known for people in the Western world and some parts in Asia due to health benefits reported by various respectable institutes' research and supported by health advocates.
In the clinically stable, adult outpatients with SZ (n=286) completed baseline assessments randomized to treatment as usual (TAU), supervised yoga training with TAU (YT) or supervised physical exercise training with TAU (PE) researchers at the joint study led by the University of Pittsburgh filed the following results
* After six months and follow up, yoga showed a significant improvement of speed index of attention domain compared to control groups.
* In cognitive domains, yoga group demonstrated a significant improvement compared to PE and with TAU alone, respectively
The further assessment also suggested that both YT and PE improved attention and additional cognitive domains well past the training period, but only the YT group showed a beneficial effect of on speed index of attention domain.
These results of improvement may be attributed to the repeated practice of attentional focus and redirecting attention may be a possible active ingredient for developing greater attentional control
Moreover, the physical and cognitive benefits associated with yoga and mindfulness may be due to mechanisms that activated the parasympathetic nervous system through meditative or contemplative practices.
Some researchers also suggested long-term yoga practice increases body perception, stronger functional connectivity within the basal ganglia and increased activation of grey matter volume and amygdala with regional enlargement.
Additionally, in the review literature published in the databases of MEDLINE, PubMed, Embase, CINAHL, BIOS, AMED, PsychINFO involved randomised controlled trials (RCTs) including people with schizophrenia comparing yoga as a package of care with standard-care control, researchers found only 3 studies with all outcomes were short-term (less than eight weeks) with none of them displayed a significant change of yoga group in compared to control.
The findings indicated that short-term yoga practice may have a little effect of improvement of cognitive function.
More importantly, in patients perspective, a study of total of 100 schizophrenia patients (male: female = 57:43; age: 35.8 ± 9.2 years) attending the psychiatry out-patient services of a tertiary neuropsychiatry hospital administered a survey questionnaire, researchers at the National Institute of Mental Health and Neuro Sciences reported the following results
* 46% participant was aware that yoga is also one of the complementary therapies useful in schizophrenia.
* 32% had tried yoga in the past for some reasons, but only 31% of them were continuing yoga with reasons of lack of motivation (31%) and inability to spare time (27.6%).
* However, the majority (88.5%) of them were willing to take up add-on yoga therapy on out-patient basis along with their regular medical follow-up.
Taking all together, long-term yoga lesson may be used as a secondary and therapeutic enhancement of cognitive function in patients with schizophrenia.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton, Master of Nutrition
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Yoga as part of a package of care versus standard care for schizophrenia by Broderick J1, Vancampfort D.(PubMed)
(2) A randomized controlled trial of adjunctive yoga and adjunctive physical exercise training for cognitive dysfunction in schizophrenia by Bhatia T1, Mazumdar S2, Wood J3, He F2, Gur RE4, Gur RC4, Nimgaonkar VL5, Deshpande SN6.(PubMed)
(3) Yoga for schizophrenia: Patients' perspective by Govindaraj R1, Varambally S1, Gangadhar BN1.(PubMed)
(4) Effects of weekly one-hour Hatha yoga therapy on resilience and stress levels in patients with schizophrenia-spectrum disorders: an eight-week randomized controlled trial by Ikai S1, Suzuki T, Uchida H, Saruta J, Tsukinoki K, Fujii Y, Mimura M.(PubMed)
(5) A yoga program for cognitive enhancement by (PMC)
Wednesday, December 26, 2018
Dried Peas Delay and Decrease Postprandial Plasma Glucose and Insulin Concentrations Effectively In Type 2 Diabetes, Scientists Find
Scientists may have found a whole food with a potential effect of management of type 2 diabetes, some studies suggested.
Types 2 Diabetes is a chronic and medical condition characterized insufficient insulin entering the bloodstream to neutralize the levels of glucose.
Types 2 Diabetes is caused either by cells in pancreas dying off or receptor sites clogged up by fat and cholesterol.
In some cases, diabetes can also be caused by allergic reactions of cells in the immune system.
The exact causes of type 2 diabetes are unknown as researchers do not know why? people with same
health condition, some are susceptible to early onset of type 2 diabetes, while others do not.
However, some researchers suggested there are some major risk factors such as genetics and lifestyle associated with early onset of insulin resistance.
Epidemiological studies also suggested that conditions such as overweight, obesity, physical inactivity, family history, race, age, and high blood pressure are some prevalent risk factors of type 2 diabetes, especially, in women with polycystic ovary syndrome and previous gestational diabetes.
According to the World Health Organization, the number of people with diabetes has risen from 108 million in 1980 to 422 million in 2014.
The global prevalence of diabetes among adults over 18 years of age has risen from 4.7% in 1980 to 8.5% in 2014.
Diabetes prevalence has been rising more rapidly in middle- and low-income countries.
Sadly, untreated or improperly managed diabetes are leading causes of kidney failure, lower-limb amputations, and adult-onset blindness.
Dried peas are a small but nutritionally mighty member of the legume family, genus Pisum belongings to the family Fabaceae.
Fried peas also healthy sources of protein, fiber, vitamins and minerals that are good for everyone diet.
The Nutrients and Chemical constituents
1. Carbohydrates
2. Dietary fiber
3. Fat
4. Protein
5. Vitamin A ( Beta-carotene, lutein, and zeaxanthin)
6. B vitamins
7. Vitamin C
8. Calcium
9. Iron
10. Magnesium
11. Phosphorus
12. Potassium
13. Zinc Beside it main component of Polyphenolic compounds, it also contains saponin pisatin, L-pipecolic acid, glycoside-Pisatoside, tocopherols,.... and cerebroside.
To understand more of low-glycemic response versus a high glycemic response breakfast meal on postprandial serum glucose, insulin and free fatty acid (FFA) responses after consumption of a standardized mid-day meal in adult individuals with Type 2 diabetes mellitus (DM), researchers launched a randomized crossover intervention using control and test meals was conducted over a 3-week-period following an overnight fast of 8-10 h.
Patients included in the study were given either Breakfast (A), a high glycemic load breakfast meal consist of farina (kJ 1833; carbohydrate (CHO) 78 g and psyllium soluble fiber 0 g) or breakfast (B) a low-glycemic load breakfast meal consists of a fiber-loop cereal (kJ 1515; CHO 62 g and psyllium soluble fiber 6.6 g) randomly.
Forty-five Type 2 DM subjects included in the study have completed the requirements. By observation of post-breakfast analyses experiment, researchers found that
* Breakfast B had a significantly lower area under the curve (AUC) values for plasma glucose and insulin compared to Breakfast A (P<0.05).
* Post-lunch analyses indicated similar glucose responses for the two breakfast types.
* Insulin AUC values for Breakfasts B were significantly lower than Breakfast A (P<0.05) (95% confidence level).
These result suggested that psyllium soluble fiber have a strong effect to reduce fasting glucose compared to a meal without. However, intake of psyllium soluble fiber showed insignificant improvement postprandially in the glycemic, insulinemic and FFA responses after the consumption of the lunch meal.
Dr. Clark CA, the lead researcher also indicated, "These data revealed no residual postprandial effect of the psyllium soluble fiber breakfast meal beyond the second meal consumed".
Additionally, in the study to evaluate the glycemic and insulinemic effects of dried peas compared to potatoes researchers at the University of Göttingen conducted a study, using 3 different meals based on dried peas, potatoes, or both in patients with type 2 diabetes undergoing dietary treatment.
The tested meals were prepared according to local recipes and consumed at weekly intervals in random order at lunchtime, contained comparable amounts of carbohydrate, fat, protein, and water. The carbohydrate source of the meals differed and was supplied from either dried peas (meal 1), potatoes (meal 3), or a combination thereof (meal 2). Peripheral and venous blood was sampled over 180 min.
In the final report, researchers wrote,
* The increases in postprandial plasma glucose and insulin concentrations were delayed and significantly smaller after the peameal than after the potato meal.
* The areas under the glucose curve were 164, 257 and 381 mmol x 180 min/L for meals 1, 2, and 3, respectively (P < 0.01).
* The areas under the insulin curve were 13.8, 15.4 and 31.2 nmol x 180 min/L, respectively.
These results further reaffirm the effect of dried peas in delay and lower postprandial plasma glucose and insulin concentrations compared to potatoes.
Interestingly, researchers also strongly suggested, "..... carbohydrates in dried peas may be largely disregarded in carbohydrate counting and that type 2 diabetic patients should probably increase their consumption of low-glycemic, high-fiber foods at the expense of high-glycemic, low-fiber foods".
Taken together, dried peas may be considered as a functional food for diabetes management by reducing postprandial plasma glucose and insulin concentrations in patients with type 2 diabetes.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299
References
(1) Effects of breakfast meal composition on second meal metabolic responses in adults with Type 2 diabetes mellitus by Clark CA, Gardiner J, McBurney MI, Anderson S, Weatherspoon LJ, Henry DN, Hord NG. (PubMed)
(2) Comparison of the effects of dried peas with those of potatoes in mixed meals on postprandial glucose and insulin concentrations in patients with type 2 diabetes by Schäfer G, Schenk U, Ritzel U, Ramadori G, Leonhardt U.(PubMed)
Tuesday, December 25, 2018
Green tea, The Beverage Kills Bacterial Staphylococcus and Streptococcus That Cause Cellulitis
Green tea may have a therapeutic and positive effect of reducing risk and treatment of cellulitis, some scientists suggested.
The results of the investigation were evaluated by numbers of respectable institutes, including the University of Indonesia and Mashhad University of Medical Sciences and published online in some medical literature databases including PubMed.
Cellulitis is a common and serious bacterial skin infection that affects the deep layer of skin, caused mostly by Staphylococcus and Streptococcus bacteria, inducing symptoms of a red, swollen skin rash (usually on the lower legs or arms) that feels tender and hot.
The skin infectious disease can appear anywhere in the body, however, in most cases, it affects the skin of the lower legs.
Some researchers suggested that people with a weakened immune system such as age population and intake of immune suppressive drugs and obesity are most likely to develop cellulitis.
As always, most cases of cellulitis are treated with antibiotics in a period of 5-10 days. Please make sure that you discuss the side effects of the medicine with your doctor.
Although it is rare, some people with severe cellulitis that experience severe symptoms of high fever or vomiting and fails to respond to treatment.
Recurrences of cellulitis may require antibiotics that are given by IV.
Green tea is a precious drink processed numbers of health benefit known to almost everyone in Asia and the Western world.
In the searching of natural antibiotics against skin infection such as cellulitis, by reviewing some plants for the treatment of skin diseases taken place during the past 17 year using the of plants is as old as the mankind, researchers found that green tea with abundant polyphenols, epigallocatechin gallate exerts a strong effect as antioxidants to reduce the risk of skin diseases, including tumors, herpes, and cellulitis.
According to the National Center for Complementary and Alternative Medicine, application of EGCG also demonstrated potential in rejuvenated old skin cells.
Further analysis of green tea catechins, the major green tea polyphenols, exhibited antimicrobial activity against resistant pathogens in induction of skin infection, including cellulitis, researchers at the Mashhad University of Medical Sciences conducted a study to determine the minimum inhibitory concentration (MIC) and the minimum bactericidal concentration (MBC) values of different agents against bacterial strains, through assessing the interactions of green tea extract, epigallate catechin, epigallocatechin gallate, two types of methylxanthine, caffeine, and theophylline with gentamicin against standard and clinical isolates of Staphylococcus aureus (S. aureus) and the standard strain of Pseudomonas aeruginosa (P. aeruginosa).
According to the final phase of the experiment, researchers indicated that
*The MICs of gentamicin against bacterial strains were in the range of 0.312 - 320 μg/mL and the MIC values of both types of catechins were 62.5 - 250 μg/ mL.
* Green tea extract showed insufficient antibacterial activity when used alone
* Methylxanthines had no intrinsic inhibitory activity against any of the bacterial strains tested.
* When green tea extract and catechins were combined with gentamicin, the MIC values of gentamicin against the standard strains and a clinical isolate were reduced, and synergistic activities were observed (FICI < 1).
* A combination of caffeine with gentamicin did not alter the MIC values of gentamicin.
The results of all comparison after taking into account of other co and confounders revealed that green tea extract and catechins potentiated the antimicrobial action of gentamicin against some clinical isolates of S. aureus and standard P. aeruginosa strains", Dr. Fazly Bazzaz BS, the lead author said.
Moreover, the evaluate the antibacterial activity of the Indonesian water soluble green tea extract, Camellia sinensis, against clinical isolates of methicillin-resistant Staphylococcus aureus (S. aureus) (MRSA) and multi-drug resistant Pseudomonas aeruginosa (MDR-P. aeruginosa) also lends a support of the above differentiation.
According to the University of Indonesia,
* The inhibition zone diameter of green tea extracts for S. aureus ATCC 25923 and MRSA were (18.970 ± 0.287) mm, and (19.130 ± 0.250) mm respectively.
* While the inhibition zone diameter for P. aeruginosa ATCC 27853 and MDR-P. aeruginosa were (17.550 ± 0.393) mm and (17.670 ± 0.398) mm respectively.
* The MIC of green tea extracts against S. aureus ATCC 25923 and MRSA were 400 µg/mL and 400 µg/mL, respectively.
* Finally, the MIC for P. aeruginosa ATCC 27853 and MDR-P. aeruginosa were 800 µg/mL, and 800 µg/mL, respectively.
Taken together, green tea and its bioactive compounds may be considered as a functional food for reduced risk and treatment of cellulitis caused by Staphylococcus and Streptococcus bacterial infection.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Plants used to treat skin diseases by Nahida Tabassum and Mariya Hamdani(PMC)
(2) Effect of Catechins, Green tea Extract, and Methylxanthines in Combination with Gentamicin Against Staphylococcus aureus and Pseudomonas aeruginosa: - Combination therapy against resistant bacteria by Fazly Bazzaz BS1, Sarabandi S2, Khameneh B3, Hosseinzadeh H4.(PubMed)
(3) Antimicrobial activity of green tea extract against isolates of methicillin-resistant Staphylococcus aureus and multi-drug resistant Pseudomonas aeruginosa by Radji M1, Agustama RA, Elya B, Tjampakasari CR.(PubMed)
The results of the investigation were evaluated by numbers of respectable institutes, including the University of Indonesia and Mashhad University of Medical Sciences and published online in some medical literature databases including PubMed.
Cellulitis is a common and serious bacterial skin infection that affects the deep layer of skin, caused mostly by Staphylococcus and Streptococcus bacteria, inducing symptoms of a red, swollen skin rash (usually on the lower legs or arms) that feels tender and hot.
The skin infectious disease can appear anywhere in the body, however, in most cases, it affects the skin of the lower legs.
Some researchers suggested that people with a weakened immune system such as age population and intake of immune suppressive drugs and obesity are most likely to develop cellulitis.
As always, most cases of cellulitis are treated with antibiotics in a period of 5-10 days. Please make sure that you discuss the side effects of the medicine with your doctor.
Although it is rare, some people with severe cellulitis that experience severe symptoms of high fever or vomiting and fails to respond to treatment.
Recurrences of cellulitis may require antibiotics that are given by IV.
Green tea is a precious drink processed numbers of health benefit known to almost everyone in Asia and the Western world.
In the searching of natural antibiotics against skin infection such as cellulitis, by reviewing some plants for the treatment of skin diseases taken place during the past 17 year using the of plants is as old as the mankind, researchers found that green tea with abundant polyphenols, epigallocatechin gallate exerts a strong effect as antioxidants to reduce the risk of skin diseases, including tumors, herpes, and cellulitis.
According to the National Center for Complementary and Alternative Medicine, application of EGCG also demonstrated potential in rejuvenated old skin cells.
Further analysis of green tea catechins, the major green tea polyphenols, exhibited antimicrobial activity against resistant pathogens in induction of skin infection, including cellulitis, researchers at the Mashhad University of Medical Sciences conducted a study to determine the minimum inhibitory concentration (MIC) and the minimum bactericidal concentration (MBC) values of different agents against bacterial strains, through assessing the interactions of green tea extract, epigallate catechin, epigallocatechin gallate, two types of methylxanthine, caffeine, and theophylline with gentamicin against standard and clinical isolates of Staphylococcus aureus (S. aureus) and the standard strain of Pseudomonas aeruginosa (P. aeruginosa).
According to the final phase of the experiment, researchers indicated that
*The MICs of gentamicin against bacterial strains were in the range of 0.312 - 320 μg/mL and the MIC values of both types of catechins were 62.5 - 250 μg/ mL.
* Green tea extract showed insufficient antibacterial activity when used alone
* Methylxanthines had no intrinsic inhibitory activity against any of the bacterial strains tested.
* When green tea extract and catechins were combined with gentamicin, the MIC values of gentamicin against the standard strains and a clinical isolate were reduced, and synergistic activities were observed (FICI < 1).
* A combination of caffeine with gentamicin did not alter the MIC values of gentamicin.
The results of all comparison after taking into account of other co and confounders revealed that green tea extract and catechins potentiated the antimicrobial action of gentamicin against some clinical isolates of S. aureus and standard P. aeruginosa strains", Dr. Fazly Bazzaz BS, the lead author said.
Moreover, the evaluate the antibacterial activity of the Indonesian water soluble green tea extract, Camellia sinensis, against clinical isolates of methicillin-resistant Staphylococcus aureus (S. aureus) (MRSA) and multi-drug resistant Pseudomonas aeruginosa (MDR-P. aeruginosa) also lends a support of the above differentiation.
According to the University of Indonesia,
* The inhibition zone diameter of green tea extracts for S. aureus ATCC 25923 and MRSA were (18.970 ± 0.287) mm, and (19.130 ± 0.250) mm respectively.
* While the inhibition zone diameter for P. aeruginosa ATCC 27853 and MDR-P. aeruginosa were (17.550 ± 0.393) mm and (17.670 ± 0.398) mm respectively.
* The MIC of green tea extracts against S. aureus ATCC 25923 and MRSA were 400 µg/mL and 400 µg/mL, respectively.
* Finally, the MIC for P. aeruginosa ATCC 27853 and MDR-P. aeruginosa were 800 µg/mL, and 800 µg/mL, respectively.
Taken together, green tea and its bioactive compounds may be considered as a functional food for reduced risk and treatment of cellulitis caused by Staphylococcus and Streptococcus bacterial infection.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Plants used to treat skin diseases by Nahida Tabassum and Mariya Hamdani(PMC)
(2) Effect of Catechins, Green tea Extract, and Methylxanthines in Combination with Gentamicin Against Staphylococcus aureus and Pseudomonas aeruginosa: - Combination therapy against resistant bacteria by Fazly Bazzaz BS1, Sarabandi S2, Khameneh B3, Hosseinzadeh H4.(PubMed)
(3) Antimicrobial activity of green tea extract against isolates of methicillin-resistant Staphylococcus aureus and multi-drug resistant Pseudomonas aeruginosa by Radji M1, Agustama RA, Elya B, Tjampakasari CR.(PubMed)
Monday, December 24, 2018
Cruciferous Vegetables, The Natural Chemopreventive Veggies Protect Our Body Against Cancers Caused by Chemical Toxins, Scientists Reveal
Cruciferous vegetables, rich of phytochemicals may be considered as the functional food for prevention of cancers caused by chemical carcinogens some studies suggested.
Chemical carcinogens, types of chemical toxins, can induce cellular and chromosomes change and DNA damage, causing mutation of healthy cells, the initial stage of cancer development.
According to the National Toxicology Program 14th Report on Carcinogens “Known to be human carcinogens” provided by the American Cancer Society, there are many different types of chemical carcinogens, including
* Lifestyle factors (nutrition, tobacco use, physical activity, etc.)
* Naturally occurring exposures (ultraviolet light, radon gas, infectious agents, etc.)
* Medical treatments (radiation and medicines including chemotherapy, hormone drugs, drugs that suppress the immune system, etc.)
* Workplace Exposures
* Household exposures
* Pollution
Cancers are class of medical diseases characterized by cell multiply disorderly and uncontrollably.
At the advanced stage, most cancers can travel a distance away from the site of origin to infect other healthy cells and tissue via lymph and blood.
According to the Universidade Federal de Ouro Preto, sulforaphane (SFN), the isothiocyanate (ITC) group of organosulfur compounds found in cruciferous vegetable expressed chemopreventive properties involved detoxification processes of chemical carcinogens.
Dr. de Figueiredo SM, the lead author said, " In a dose-dependent manner, ITC inhibits the viability of human cancer cells, modifies epigenetic events that occur in cancer cells and present antiinflammatory effect acting during the initial of uncontrolled cell proliferation."
The chemoprotective activity of the cruciferous vegetable was attributed to significant expression of the antioxidants in cell cycle arrest and apoptosis of cancer cells.
Furthermore, its phytochemicals also can act as the post-initiation stages of carcinogenesis, 'suppressing' agent involving the ability to modulate the Nrf2 which is a protein with unique function of regulating expression of antioxidant proteins that protect against oxidative damage triggered by injury and inflammation.
In fact, besides using as a chemopreventive agent against chemical carcinogenesis, sulforaphane (SFN), the major chemical constituent of cruciferous vegetables also inhibited the drug-metabolizing enzymes that cause activation/neutralization of carcinogenic metabolites and protected normal healthy cells from environmental toxin inducing of cancers.
Moreover, the phytochemical exhibited the molecular mechanisms responsible for the overall chemopreventive effects on selective cytotoxicity, the unique function of inhibiting oxidate stress, free radicals produced by lipid peroxidation in cells.
Additionally, in tobacco smoke carcinogens induced chemical tumors, cruciferous vegetable consumption has shown to inversely associate the development of cancer.
In animal experiments. the chemopreventive effects of isothiocyanates, another compound found cruciferous vegetable, inhibited the metabolic activation of carcinogens by cytochrome P450s, enzymes with the function of metabolized potentially toxic compounds.
Taking together, intake of cruciferous vegetables have a potential health benefit against environment toxins that initiates the early onset of cancers. But due to the small size of the sample, further studies are necessary to address the veggies anti cancers possibility.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blog, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Chemoprotection by sulforaphane: keep one eye beyond Keap1 by Myzak MC1, Dashwood RH.(PubMed)
(2) The antioxidant properties of organosulfur compounds (sulforaphane) by de Figueiredo SM1, Binda NS, Nogueira-Machado JA, Vieira-Filho SA, Caligiorne RB.(PubMed)
(3) Role of 4-hydroxynonenal in chemopreventive activities of sulforaphane by Sharma R1, Sharma A, Chaudhary P, Sahu M, Jaiswal S, Awasthi S, Awasthi YC.(PubMed)
Chemical carcinogens, types of chemical toxins, can induce cellular and chromosomes change and DNA damage, causing mutation of healthy cells, the initial stage of cancer development.
According to the National Toxicology Program 14th Report on Carcinogens “Known to be human carcinogens” provided by the American Cancer Society, there are many different types of chemical carcinogens, including
* Lifestyle factors (nutrition, tobacco use, physical activity, etc.)
* Naturally occurring exposures (ultraviolet light, radon gas, infectious agents, etc.)
* Medical treatments (radiation and medicines including chemotherapy, hormone drugs, drugs that suppress the immune system, etc.)
* Workplace Exposures
* Household exposures
* Pollution
Cancers are class of medical diseases characterized by cell multiply disorderly and uncontrollably.
At the advanced stage, most cancers can travel a distance away from the site of origin to infect other healthy cells and tissue via lymph and blood.
According to the Universidade Federal de Ouro Preto, sulforaphane (SFN), the isothiocyanate (ITC) group of organosulfur compounds found in cruciferous vegetable expressed chemopreventive properties involved detoxification processes of chemical carcinogens.
Dr. de Figueiredo SM, the lead author said, " In a dose-dependent manner, ITC inhibits the viability of human cancer cells, modifies epigenetic events that occur in cancer cells and present antiinflammatory effect acting during the initial of uncontrolled cell proliferation."
The chemoprotective activity of the cruciferous vegetable was attributed to significant expression of the antioxidants in cell cycle arrest and apoptosis of cancer cells.
Furthermore, its phytochemicals also can act as the post-initiation stages of carcinogenesis, 'suppressing' agent involving the ability to modulate the Nrf2 which is a protein with unique function of regulating expression of antioxidant proteins that protect against oxidative damage triggered by injury and inflammation.
In fact, besides using as a chemopreventive agent against chemical carcinogenesis, sulforaphane (SFN), the major chemical constituent of cruciferous vegetables also inhibited the drug-metabolizing enzymes that cause activation/neutralization of carcinogenic metabolites and protected normal healthy cells from environmental toxin inducing of cancers.
Moreover, the phytochemical exhibited the molecular mechanisms responsible for the overall chemopreventive effects on selective cytotoxicity, the unique function of inhibiting oxidate stress, free radicals produced by lipid peroxidation in cells.
Additionally, in tobacco smoke carcinogens induced chemical tumors, cruciferous vegetable consumption has shown to inversely associate the development of cancer.
In animal experiments. the chemopreventive effects of isothiocyanates, another compound found cruciferous vegetable, inhibited the metabolic activation of carcinogens by cytochrome P450s, enzymes with the function of metabolized potentially toxic compounds.
Taking together, intake of cruciferous vegetables have a potential health benefit against environment toxins that initiates the early onset of cancers. But due to the small size of the sample, further studies are necessary to address the veggies anti cancers possibility.
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Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blog, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Chemoprotection by sulforaphane: keep one eye beyond Keap1 by Myzak MC1, Dashwood RH.(PubMed)
(2) The antioxidant properties of organosulfur compounds (sulforaphane) by de Figueiredo SM1, Binda NS, Nogueira-Machado JA, Vieira-Filho SA, Caligiorne RB.(PubMed)
(3) Role of 4-hydroxynonenal in chemopreventive activities of sulforaphane by Sharma R1, Sharma A, Chaudhary P, Sahu M, Jaiswal S, Awasthi S, Awasthi YC.(PubMed)
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