Beware of Excessive Coffee and Coffee Caffeine Intake In the Risk Of Pregnancy Loss, Scientists Suggest

Bad news for pregnant women and coffee lovers, excessive maternal caffeinated coffee intake may associate to increased risk of pregnancy loss, some studies suggested

Pregnancy loss is a natural death of an embryo or fetus before it is born, including spontaneous abortion, miscarry, stillbirth...

Coffee, becoming a popular and social beverage all over the world, particularly in the West, is a drink made from roast bean from the Coffea plant, native to tropical Africa and Madagascar.

In a total of 130 456 participants and 3429 cases in fourteen included studies, researchers found that women with
* No or very low caffeine intake, have a relative risk of pregnancy loss of 1.02.

* Moderate intake (150-349 mg/d) showed an increased relative risk of 1·16.

* High intake (350-699 mg/d) showed a relative risk of 1·40.

* Very high intake (≥ 700 mg/d) showed a relative risk of 1·72

The risks of pregnancy loss were increased linearly and correlatively to numbers of a cup of coffee intake per day.

According to the joint study led by the National University of Singapore and National University Health System, additional intake of 1 cup of coffee in women who are regular coffee drinkers similar to 100 mg/d increment caffeine intake was associated with 7% higher risk of pregnancy loss.

Furthermore, a case-control and cohort review study reported in English, the exposure of caffeine/coffee consumption during pregnancy, from selected 26 studies included (20 of caffeine and eight of coffee) suggested that the relative risk ratio of pregnancy loss due to caffeine consumption was 1.32

The study also found that risk of pregnancy loss increased substantially to 19% for every increased caffeine intake of 150 mg/day and every additional 2 cups of coffee intake, the risk of pregnancy loss increased by 8%.

The findings suggested that excessive maternal caffeinated coffee intake is associated to increase the risk of pregnancy loss. However, researchers can not explain why? pregnant women with the same health condition and gestation age, some are susceptible to pregnancy loss while others do not.

These results might suggest that although excessive coffee intake during pregnancy is considered a risk factor, there must be some others unknown risk factors involved in the manifestation of the onset of the loss.

Truly, there are many implications associated with pregnancy loss including ages of the father, genetic mutation or polymorphism in the father that can lead to the production abnormal chemicals or hormones by the embryo, sperm quality sperm chromosomes, ..... and unhealthy lifestyle choice of the father may also associate to the risk of pregnancy loss.

Dr. By Dr. Suhasini Inamdar, in the article "A man’s unhealthy lifestyle may also be responsible for a miscarriage: posed in the Economic Time wrote, "Men who drink alcohol heavily also have lower sperm motility and concentration. - Excess coffee consumption can further lead to reduced sperm concentration and count. Men who eat red meat have lower implantation and resultant pregnancy rates as well. Not getting enough vitamin D and vitamin B12"

Taking all together, there is no doubt that excessive intake of coffee during pregnancy-induced high risk of pregnancy loss but according to the statistic, North American women seldom drink more than 4 cups/day so we may be in the safe zones.

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Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.

Sources
(1) Maternal caffeine intake during pregnancy and risk of pregnancy loss: a categorical and dose-response meta-analysis of prospective studies by Chen LW1, Wu Y1, Neelakantan N1, Chong MF2, Pan A1, van Dam RM1.(PubMed)
(2) A meta-analysis of the risk of pregnancy loss and caffeine and coffee consumption during pregnancy by Li J1, Zhao H2, Song JM3, Zhang J4, Tang YL5, Xin CM6.(PubMed)

Yoga, the Integrated form of Exercise in Alleviating Symptoms of Polycystic Ovarian Syndrome (PCOs)

Yoga therapy may be considered an integrated form of exercise in reducing symptoms in women with Polycystic ovarian syndrome.

The polycystic ovarian syndrome is an endocrinologic disease among reproductive-age women caused by undeveloped follicles clumping on the ovaries that interfere with the function of the normal ovaries, associated with a high risk for the metabolic disorder.

Sadly, women with PCOs also have a higher risk of menstrual disorders, infertility, abnormal levels of hormone levels.

Certain medical conditions are also found to associate to the onset of PCOs such as type 2 diabetes, high blood pressure and high cholesterol, and triglycerides.

Researchers do not know why women who process the same health condition and follow a similar diet pattern, some are susceptible to the onset of the syndrome, while others do not.

However, epidemiological studies suggested that family history of PCOs, fast food diet habits, body mass index and waist circumference are possible risk factors for the development of PCOS.

Some researchers also suggested that the mutated gene inherited from the parents are also a major factor that causes PCOs, including gene CYP11a.

Most common symptoms of PCOs include overexpression of acne, overweight or obesity, abdominal pain, the excessive male pattern of hair growth on the face, nipple area, chest, lower abdomen, bald spots, dark patches. In some women. The syndrome also can lead to psychological symptoms of anxiety and depression.

Treatment of PCOs is totally depended on the presence of the symptoms including medication for treatment of overexpression of hormone androgen and insulin resistance.

Yoga, the ancient technique for harmonized external and internal body well being, through breath control, meditation, bodily movement, and gesture..... has been well known for people in the Western world and some parts in Asia.


In a study of Ninety (90) adolescent (15-18 years) girls from a residential college in Andhra Pradesh satisfied the Rotterdam criteria and randomly assigned into 2 groups with yoga group practiced a holistic yoga module, while the control group practiced a matching set of physical exercises (1 hour/day, for 12 weeks), researchers after adjusting to other co confounders, showed that
*Yoga group expressed a significant change in hormones Anti-müllerian hormone AMH luteinizing hormone (LH), follicle-stimulating hormone (FSH) and LH/FSH ratio and particularly in hormone testosterone, compared to control.

* Yoga group also showed an improvement of The Ferriman–Gallwey score in evaluating and quantifying Hirsutism.

* There were an insignificant change of FSH and prolactin after intervention in both groups.

*4. More importantly, yoga group displayed favorably in changes of menstrual frequency compared to control

Dr. Nidhi R, the led author after reviewing the efficacy in yoga group, said, "A holistic yoga program for 12 weeks is significantly better than physical exercise in reducing AMH, LH, and testosterone, mFG score for hirsutism, and improving menstrual frequency with nonsignificant changes in body weight, FSH, and prolactin in adolescent PCOS"

The efficacy of yoga practice in reducing the expression of the male pattern of hair growth and changes of menstrual frequency is attributed to meditation and slow breathing in calming the central nervous system in response to hormone production. Thus reducing overexpression of certain hormones that associate to the symptoms of PCOs.


Additionally, in the investigated yoga therapy in the reduced primary symptoms of glucose metabolism and blood lipid levels in adolescent girls with polycystic ovary syndrome in same above group met the Rotterdam criteria for PCOS, researchers found that
* Yoga intervention displays a significant improvement of fasting insulin, fasting blood glucose, and homeostasis model assessment of insulin resistance compared to control.

* Yoga group also expresses a strong effect in blood lipid values except for high-density lipoprotein cholesterol.

* There was no change of body mass index, waist circumference, hip circumference, and waist-to-hip ratio, in both groups

Interestingly, in the study of possible use of Kapalabhati yoga technique to combat metabolic syndrome (MS) and polycystic ovarian syndrome (PCOS), researchers at the Cyberjaya University College of Medical Sciences conducted a review of published literature from PubMed, Scopus, and found that Kapalabhati may be helpful in reducing symptoms of various features of MS, but its efficacy against PCOS had not been found.

Dr. Ansari RM after adjusting to other aspects said, "since both syndromes arise due to common factor hyperinsulinemia primarily induced by stress in this modern world, it is hypothesized that Kapalabhati holds good against PCOS too ".

How yoga exhibited these kinds of effect are unclear, However, according to the article "Yoga for a Metabolic Makeover" written by CATHERINE GUTHRIE stress relief and feelings of well-being fostered by a regular yoga practice serve to rebalance the nervous system may be the major factor that has a strong effect in the improvement of metabolic syndrome through reducing the overexpression of pro-inflammatory cytokine in facilitating the onset of type 2 diabetes and lipid peroxidation, thus reducing the risk of insulin resistance and high blood cholesterol"


The information collected from the above differentiation suggested that yoga may be used as a secondary and integrated form of exercise combined with standard treatment in reducing the symptoms of PCOs.

Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca


Author Biography
Kyle J. Norton, Master of Nutrition
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.


Sources
(1) Effects of a holistic yoga program on endocrine parameters in adolescents with polycystic ovarian syndrome: a randomized controlled trial by Nidhi R1, Padmalatha V, Nagarathna R, Amritanshu R.(PubMed)
(2) Effect of a yoga program on glucose metabolism and blood lipid levels in adolescent girls with polycystic ovary syndrome by Nidhi R1, Padmalatha V, Nagarathna R, Ram A.(PubMed)
(2) Kapalabhati pranayama: An answer to modern day polycystic ovarian syndrome and coexisting metabolic syndrome? by Ansari RM1.(PubMed)

Yoga Improves Psychological and Physical Symptoms and Quality of Life in Ulcerative Colitis Patients

Yoga may be used as secondary therapy in improved psychological and physical activities and enhanced quality of life in patients with ulcerative colitis, studies suggested

Ulcerative colitis is one form of inflammatory bowel disease (IBD) characterized by long-lasting inflammation and ulcers (sores) in the digestive tract.

Yoga, the ancient practice for harmonized external and internal body well being, through breath control, meditation, bodily movement, and gesture..... has been well known for people in the Western world and some parts in Asia.

In the study of a total of 77 patients (75% women; 45.5 ± 11.9 years) with ulcerative colitis in clinical remission due to impaired quality of life randomly assigned to yoga (12 supervised weekly sessions of 90 min; n = 39) researchers indicated that
* Yoga group improved a significant quality of life compared to control after 12 weeks of the lesson, and additionally, at week 12, the improvement in yoga group reached a clinically relevant increase in quality of life.

* Yoga participants also expressed a reduced activity of the disease after 24 weeks.

* Only 3 patient experienced serious adverse events
Dr. Cramer H, the led author after adjusting to other factors said, "Yoga can be considered as a safe and effective ancillary intervention for patients with ulcerative colitis and impaired quality of life".

The improvement of quality of the life in tested subjects due to the reduction of physical and psychological symptoms was attributed to yoga slow breathing, meditation in enhancing the function of the central nervous system in hormone rebalancing which has a strong impact in the inhibition of psychological symptoms in the participants and yoga posture in strengthening the muscles and promoting blood circulation to the body need for physical activity, thus reducing physical symptoms.


Additionally, in support to the above analysis, researchers at the joint study led by All India Institute of Medical Sciences conducted a study of 100 IBD patients [ulcerative colitis (UC) n = 60 and Crohn's disease (CD) n = 40] during the clinical remission phase of disease, randomly assigned to either the yoga group with an 8-week yoga intervention (physical postures, pranayama, and meditation), 1- hour/day in addition to standard medical therapy (UC, n = 30; CD, n = 20) or the control group (UC, n = 30; CD n = 20), researchers after taking into account co and confounders found the below interesting results
* Yoga group displayed a reduction of UC patients in reported arthralgia, compared to control

* Numbers of Yoga group experienced reduced intestinal colic pain were lower compared to higher in the control group.

3. Yoga participants also expressed an improvement of state and trait anxiety levels.

These results suggested that yoga practice with meditation and slow breathing also have a strong effect in influence the hormone production of the central nervous system. By calming the central nervous system in reducing overproduction of certain hormones that are responsible for muscle constriction, thus decreasing pain.

Taking all together, yoga may be considered an integrated form of exercise for improvement of psychological and physical activities and quality of life in ulcerative colitis patients without inducing any side effects.


Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight

How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca


Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.


Sources
(1) Randomised clinical trial: yoga vs written self-care advice for ulcerative colitis by Cramer H1,2, Schäfer M1,3, Schöls M1,3,4, Köcke J1,3, Elsenbruch S4, Lauche R1,2, Engler H4, Dobos G1, Langhorst J1,3.(PubMed)
(2) Effect of Yoga-Based Intervention in Patients with Inflammatory Bowel Disease by Sharma P1, Poojary G2, Dwivedi SN3, Deepak KK4.(PubMed)

Herbal Anise and It's Bioactive Anethole That Kill Fungi Before They Can Cause Infection

Anise may have potential and substantial antifungal effects, some scientists suggested.

Antifungal activity is the systematic immune response with an aim to protect the body against damage and injury by destroying fungal invasion during the acute phase of infection.

In the plants, certain chemicals or pigments found the outer layer is also the natural anti microorganisms agents with a function to that protect the plants against certain microorganisms in causing harm and interfering with the plants' survival.

Fungal diseases are often caused by fungi found in the environment. They are easy to treat if diagnosed early. However, untreated and late diagnosed fungal diseases may cause some serious complications such as lung infection, infertility and sometimes be life-threatening due to toxicity.

Dr. Robinson PA, the lead scientist in the study of life-threatening fungal infections in patients who cannot be treated with conventional antifungal agents, wrote, " .......in patients with serious fungal infections who failed to respond to or could not tolerate conventional antifungal therapy. Patients were enrolled if they had a life-threatening fungal infection and conventional therapy had failed to eradicate the infection, had caused serious toxic reactions, or was contraindicated".



If you are currently taking conventional medicine such as clotrimazole, econazole, or miconazole for treatment of fungal infection, please make sure that you know the adverse effects, particularly if you are taking them on a long-term basis.


Anise is a flowering plant of the species of Pimpinella anisum, genus Pimpinella, belongings to the family Apiaceae native to Egypt and the Mediterranean region, used in traditional herbal medicine as a fragrance in soaps, oils, and mouth fresheners and stomachic, antiseptic, anti-spasmodic,...

Chemical constituents
Anethole, D-pinene, I-phellandrene, Alpha-terpineol, Safrol, Methyl chavicol, Resin, Shikimic acid, etc.

In the evaluation of the antifungal activities of fluid extract and essential oil isolated from Anise researchers at the University of Zagreb found that application of Anise fluid extract displays a significant antimycotic activity against Candida albicans, C. parapsilosis, C. tropicalis, C. pseudotropicalis, and C. krusei at the minimum inhibitory concentration (MIC) between 17 and 20%

and dermatophyte species (Trichophyton rubrum, T. mentagrophytes, Microsporum canis, and M. gypseum) with MIC values between 1.5 and 9.0%.


In compared to the fluid extract, Anise essential oil showed a very strong antifungal activity in yeasts with MIC lower than 1.56% (V/V) and dermatophytes with MIC lower than 0.78% (V/V).

Further, in the examine the efficacy of fluid extract researchers surprisingly found that fluid extract not only does not exert any inhibition of species of C. glabrata but also promotes the growth of activity of Geotrichum spp. in compared to essential oil counterpart.
These results suggested that although the fluid extract and essential oil react differently in fungal inhibition, the essential oil expressed an impressively stronger antifungal activity against all species but weaker in compared to nystatin(an antifungal medication) in Geotrichum spp.



Moreover, due to the statistically significant difference of MIC values (p < 0.01) between the essential oils and the fluid extract of anise, researchers suspected that some very potent fungicidal components must be presented in the essential oil of Anise, but not in the fluid extract or only presented in a very low concentration.


Interestingly, in compared to ketoconazole(an antifungal drug), the fluid extract and essential oil of Anise pronounced a substantially higher or equal antifungal activity.


Dr. Kosalec I, after taking into account other co-founders, said, "Anise essential oil exhibited stronger antifungal activities against yeasts and dermatophytes with MIC values between 0.10 and 1.56% (V/V),(in compared to 1.5 and 9.0% of the extract), respectively".


Some researchers suggested that anethole, a major chemical compound found on Anise essential oil may be the component which exerted a significant effect against plant pathogenic fungi, according to the data obtained by hydro-distillation analyzed for its chemical composition by gas chromatography (GC) and gas chromatography-mass spectrometry (GC-MS).


Indeed, trans-Anethole of 89.5% and cis-anethole 0.7% were found in high concentration in the essential oil but not in the fluid extract.


Anethole expressed a significant antifungal effect, probably through exhibiting antioxidant activities and stimulating the natural antioxidants produced by the body to protect the healthy cell against oxidative damage induced by expression of ROS caused by the proliferation of fungal species.


More importantly, anethole also inhibited chitin, an important structural component of the cell walls of many fungi indirectly governed by an enzymatic activity in permeabilized hyphae, filaments that make up the mycelium of a fungus.in a dose-dependent manner.


These differentiations suggested that anethole may be developed as natural fungicides for plant disease control in fruit and vegetable preservation without inducing intolerantly adverse effect.


Taken together, Anise and its bioactive anethole may be considered as a functional herb for reduced risk, progression and combined with conventional medicine for treatment of fungal overgrowth.




Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight

How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca


Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.


Sources
(1) Antifungal activity of fluid extract and essential oil from anise fruits (Pimpinellaanisum L., Apiaceae). by Kosalec I1, Pepeljnjak S, Kustrak D.(PubMed)
(2) Antifungal activity of the essential oil of Illicium verum fruit and its main component trans-anethole by Huang Y1, Zhao J, Zhou L, Wang J, Gong Y, Chen X, Guo Z, Wang Q, Jiang W.(PubMed)
(3) Essential Oils and Antifungal Activity Filomena Nazzaro 1,* ID, Florinda Fratianni 1 ID, Raffaele Coppola 2 and Vincenzo De Feo(Pharmaceutical, MDPI)
(4) Fluconazole for life-threatening fungal infections in patients who cannot be treated with conventional antifungal agents by Robinson PA1, Knirsch AK, Joseph JA. (PubMed)

The Functional Herb Which Protects Our Body Against Type 2 Diabetes, Researchers Reveal

Scientists may have found a whole herb which processes anti-diabetes property, some scientists suggested.

Diabetes is a chronic condition characterized by insufficient insulin entering the bloodstream to regulate the glucose as a result of either cell in pancreas dying off or receptor sites clogged up by fat and cholesterol.

In some cases, diabetes may also be caused by allergic reactions of cells in the immune system.

The actual causes of diabetes inflammatory condition are debatable.

Some researchers also do not know why some people without genetic mutations are susceptible to type 2 diabetes while others do not.

However, certain risk factors such as overweight and obesity (overexpression of fatty tissue that causes insulin resistant), physical inactivity, family history, race,,,,, and age. ...

Women developed gestational diabetes, polycystic ovary syndrome,.... and high blood pressure is also some major risk factors associated to increase the risk of type 2 diabetes.

The first line medicine used for the treatment of type 2 diabetes is metformin which processes a significant effect in improving the body tissue sensitivity to insulin. In other words, metformin improves the body uses insulin more effectively. and lowers glucose production in the liver.

In the stage prediabetes, patients may not experience any symptoms. However, untreated diabetes or diabetes that do not manage properly, may increase the risk of cataracts and glaucoma, foot damage.

In advance stage, untreated diabetes can also cause nerve damage or poor blood flow to the feet which in turn, increases the risk of various foot complications.

Alfalfa is a flowering plant in the genus Medicago, belonging to the family Fabaceae, It has been cultivated all over the world as hay for cattle feeding.

The leaves, sprouts, and seeds to make medicine has been used in traditional medicine over thousands of year to treat high cholesterol, asthma, osteoarthritis, rheumatoid arthritis, diabetes, enhance digestive system, bleeding disorder, kidney, and urinary tract infection, etc. North America aboriginal has used Alfalfa seed as food, such as making bread and mush.

Ingredients
1. Essential amino acids
2. Calcium
3. Magnesium
4. Potassium
5. Iron
6. Phosphorus
7. Zinc
8. Beta carotene
9. vitamin C
10. vitamins D
11.Vitamin E
12. Vitamin K

It chemical constituents include flavones, isoflavones, sterols, Bichanin, Coumestrol, Diadzein, Formonetin, Genistein,.... and coumarin derivatives.

In the study to examine the Lucerne (alfalfa) effect by oral administrated the herbal extract through diet (62.5 g/kg) and drinking water (2.5 g/l) in reducing the hyperglycemia of streptozotocin-diabetic mice, researchers found
* Application of aqueous extract of lucerne exerts a significant stimulation of insulin secretion from the pancreatic B-cell line.

* Application of aqueous extract of lucern also promotes insulin-like activity in inhibited overexpression glucose.

* The sequential extraction with solvents revealed .higher insulin-releasing activity in both methanol and water fractions compared to one extract constituent.

Further analysis also suggested that the activity of the extract was found to be heat stable and enhanced by exposure to acid and alkali (0.1 M-HCl and NaOH).

Dr. Gray AM, the lead author at the final report wrote, "The results demonstrate the presence of antihyperglycaemic, insulin-releasing and insulin-like activity in the traditional antidiabetic plant, Medicago sativa".

Additionally, in the study to reaffirm the effect herbal alfalfa against onset of diabetes researchers launched a study to compare alfalfa with other herbal medicine including dried leaves of agrimony (Agrimonia eupatoria), blackberry (Rubus fructicosus), celandine (Chelidonium majus), eucalyptus (Eucalyptus globulus), lady's mantle (Alchemilla vulgaris), and lily of the valley (Convallaria majalis); seeds of coriander (Coriandrum sativum); dried berries of juniper (Juniperus communis); bulbs of garlic (Allium sativum) and roots of liquorice (Glycyrhizza glabra).

In mice administrated by streptozotocin (200 mg/kg i.p.) to induce the development of hyperphagia, polydipsia, body weight loss, hyperglycemia and hypoinsulinemia, researchers found that

* Herbal alfalfa exerts a strong effect in reduced the level of hyperglycemia during the development of streptozotocin diabetes compared to others herbs.

* Herbal alfalfa reduced polydipsia and a reduced rate of body weight loss.

* Alfalfa initially countered the hyperinsulinaemic effect of streptozotocin, without affecting the fall in plasma insulin.

Dr. said, after taking into account of other co and confounders, " The results suggest that certain traditional plant treatments for diabetes, namely alfalfa,.......can retard the development of streptozotocin diabetes in mice".

Taking all together, herbal alfalfa may be considered a functional herb for the prevention and treatment of type 2 diabetes.

However, additional data collection on large example size and multi-center clinical studies performed with human consumption of the whole food during the course of the disease will be necessary to complete the picture of alfalfa anti-type 2 diabetes possibilities.

And long-term multiple dietary supplement consumption of a broad array of vitamin/mineral, herbal, and condition-specific dietary supplements on a daily basis should consult with their doctors or related field specialist before applying.

Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca


Author Biography
Kyle J. Norton, Master of Nutrition
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.

References
(1) Pancreatic and extra-pancreatic effects of the traditional anti-diabetic plant, Medicago sativa (lucerne) by Gray AM, Flatt PR. (PubMed)
(2) Traditional plant treatments for diabetes. Studies in normal and streptozotocin diabetic mice. by Swanston-Flatt SK, Day C, Bailey CJ, Flatt PR. (PubMed)
(3) Drug-induced lupus: an update by Vasoo S.(PubMed)

The Anti Cancers Night Shade Vegetable, Scientists show

Eggplant, the nightshade vegetable may be considered a functional food for the prevention and treatment of cancers, some researchers suggested.

Cancers are class of chronic diseases caused alternation of DNA of healthy cells.

In other words, healthy cells become cancerous if they grow uncontrollably and disorderly out of range of a normal healthy cell population which can only divide between 40 and 60 times.

According to the Hayflick limit theory, most cells survival is totally dependent on the telomeres on the ends of each chromosome.

Every time, healthy cells undergo division, the telomeres are shortened. Once the telomeres shorten to a critical length, the cells will die off.

In advance stage, traveling through fluid and blood circulation, most invasive cancer cells can infect healthy cells or tissue a distance away from the originated site.

According to the statistic provided the Canadian Health Service, In 2017, over 200,000 Canadians will be diagnosed with cancer and 80,000 will die from cancer.

Sadly, 1 in 2 Canadians will be diagnosed with cancer during their lifetime and 1 in 4 will die from the disease.

Lung, colorectal, breast and prostate cancers are the most common cancer found in Canadian, accounting for half of all cancers diagnosed.

And 60% of Canadians diagnosed with cancer will survive at least 5 years after their diagnosis.

Eggplant is a species of S. melongena, belonging to the family Solanaceae and native to India.

The plant has been cultivated in southern and eastern Asia since prehistory.

Eggplant is famous with its deep purple and the best eggplant can be found from August through October when it is in season.

Nutritional Supplements
1. Carbohydrates
2. Sugars
3. Fiber
4. Fat
5. Protein
6. Thiamine (Vitamin B1)
7. Riboflavin (Vitamin B2)
8. Niacin (Vitamin B3)
9. Pantothenic acid (B5)
10. Vitamin B6
11. Folate (Vitamin B9)
12. Vitamin C
13. Tryptophan
14. Manganese
15. Calcium
16. Copper
17. Iron
18. Magnesium
19. Phosphorus
20. Potassium
21. Zinc


Chemical constituents
The vegetable chemical compounds containing include sterols (i.e. typical plant sterols, androstane, pregnane and cholestane derivatives, steroidal alkaloids, and sapogenins), phytosterols, triterpenes, δ-amyrin, Chlorogenic acid, Nasunin, and other Polyphenolic compounds.

In the effort to find the plant-derived foods such as potatoes, eggplants, and tomatoes with potential antiproliferative activities against human colon (HT29) and liver (HepG2) cancer cells, researchers at the Yeungnam University conducted a study to evaluate series of structurally related individual compounds in these plants, using microculture tetrazolium (MTT) assay.
Glycoalkaloids solamargine and solasonine and their common aglycon solasodine; and the nonsteroidal alkaloid jervine isolated from eggplant were selected to test the anti cancers possibilities compared to other compound isolated from potatoes and tomatoes.

After taking into account other factors, researchers found that
* Glycoalkaloids derived from eggplant exerts the most active anticancer cells compared to others. However, its hydrolysis products are less active compared to glycoalkaloids.

* Compounds isolated from eggplant are very effective against the liver cancer cells compared to colon cancer cells.


Dr. Lee KR, the lead author on the final report said, "....safety considerations should guide the use of these compounds preventative or therapeutic treatments against carcinomas".

Furthermore, the study to investigate the inhibitory effect of eggplant (Solanum melongena var. marunasu) extract on the human fibrosarcoma HT-1080 cell invasion of reconstituted basement membrane [Matrigel (MG)], researchers discovered

* Delphinidin, a flavonoid pigment contained in the peel demonstrates the most effective against human fibrosarcoma HT-1080 cell.

* Interestingly, application of eggplant extract and delphinidin did not affect tumor cell adhesion to MG or haptotactic migration to MG.

Further analysis of these effects, researchers found that the inhibition of cancer was attributed to
delphinidin of blocking the activity of Matrix metalloproteinases MMPs which are responsible for the degradation of most extracellular matrix proteins during organogenesis, growth and normal tissue turnover.

The findings suggested that the frequency of eggplant intake may associate to reduce the risk of cancers. However, further data collection on large example size and multi-center studies performed with human consumption of the whole food eggplant during the course of cancer will be necessary to complete the picture of eggplant and its bioactive ingredients anti-cancer possibilities.

Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca


Author Biography
Kyle J. Norton, Master of Nutrition
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.

References
(1) Glycoalkaloids and metabolites inhibit the growth of human colon (HT29) and liver (HepG2) cancer cells by Lee KR1, Kozukue N, Han JS, Park JH, Chang EY, Baek EJ, Chang JS, Friedman M.(PubMed)
(2) Inhibitory effect of delphinidin from Solanum melongena on human fibrosarcoma HT-1080 invasiveness in vitro by Nagase H1, Sasaki K, Kito H, Haga A, Sato T.(PubMed)

Green Tea, The Beverage Which Blocks The Onset of Ulcerative Colitis, Researchers Find

Green tea may have a therapeutic and positive effect for prevention and treatment of Ulcerative Colitis, some scientists suggested.

Ulcerative Colitis is a digestive condition characterized by inflammatory bowel disease (IBD) that induces chronic inflammation and ulcers (sores) in the digestive tract.

According to statistic, approximately, between 250,000 and 500,000 people are infected by ulcerative colitis in the United States. The risk of ulcerative colitis onset is between 2 to 7 per 100,000 persons.

Most common symptoms are abdominal pain and diarrhea. However, some patients may also experience symptoms of fatigue or tiredness, loss of appetite, dehydration feeling the urge to empty the bowels constantly,.... and weight loss.

If you have some of the symptoms of above, please check with your doctor to rule out the possibility of ulcerative colitis.

Researchers do not know the exact cause of Ulcerative Colitis.

Neither they know why ulcerative colitis induces chronic inflammation and ulcers (sores) in the digestive tract.

However, they do know that certain risk factors are associated to the development of the disease, including genetic mutation of a certain gene, environmental toxins, overreaction of the immune system,.... and long-term high levels of linoleic acid intake.

Green tea, a precious drink processes numbers of health benefit known to almost everyone in Asia and Western world.

As yin in nature, long-term injection of large amounts may obstruct the balance of yin-yang, induced "yin excessive syndrome" or "yang vacuity syndrome" including weaken immunity and painful case of GERD,... according to traditional Chinese medicine's Yin-Yang theory.

Mild to moderate ulcerative colitis (UC) patients, 15 received 400 mg or 800 mg of total Polyphenon E daily, administered in split doses or and 4 in placebo in a double-blinded, placebo-controlled pilot study, researchers at the end of the experiential indicated that oral administration of the extracts exerts a potential effect of reduced levels of inflammation through the improvement of the reading of the mean UC disease activity index score compared to the entry score.

After 56 days of therapy, Polyphenon E treatment group exhibited strong improvement of over response rate of 66.7% (10 of 15) and remission rate of 53.3% (8/15) compared to 0% (0/4) in both response rate and remission rate in the placebo group.

Dr. Dryden GW, the lead author, after taking into account of other co-founder said, "Administration of Polyphenon E resulted in a therapeutic benefit for(ulcerative colitis (UC)) patients who were refractory to 5-aminosalicylic and/or azathioprine".

Polyphenon E is high-quality tea catechin extracted from natural tea leaves.

Further analysis of green tea bioactive polyphenols, epigallocatechin gallate (EGCG) on dextran sulfate sodium- (DSS-) induced ulcerative colitis in rats and to explore the roles of TLR4/MyD88/NF-κB signaling pathway, indicated that application of the extract significantly improves the intestinal mucosal injury in rats though inhibited production of inflammatory factors which were overexpression during the acute phase of injuring and damage to induced further damage to the tissue.

Moreover, green tea bioactive polyphenols, epigallocatechin gallate (EGCG) also reduced chronic inflammation and maintained the balance of the ratio of Th1/Th2 T-helper (Th) lymphocytes that prevent alterations in cellular immunity in patients with ulcerative colitis.

Imbalance of Th1/Th2 was found to associate to the occurrence and development of ulcerative colitis.

Additionally, injection of green tea EGCG also reduced the levels of TLR4 signaling in activated the intracellular signaling pathway NF-κB and inflammatory cytokine production to imitate inflammation.

Amazingly, researchers also found that injection of TLR4 antagonism not only shows a significantly reduced the protective effect of EGCG on intestinal mucosal injury colitis but also increased the expressions of inflammatory factors in the production of pro-inflammatory cytokines.

Moreover, in the examine the antioxidant activity of green tea catechins in model of colitis induced by 2.4.6 trinitrobenzene sulfonic acid (TNBS) using 35 young adult Sprague-Dawley rats which are divided into four groups: normal control (n=5), catechins (n=9), TNBS (n=9) and 2.4.6 trinitrobenzene sulfonic acid (TNBS) plus catechins (n=12), at the end of the experiment researchers at the Joint study, American University of Beirut, found that groups with TNBS and catechin express strong anti-inflammatory and anti-oxidant effects of amelioration of symptoms and expression of ulcerative colitis through stabilizing the mast cells production, induced by injection of TNBS in compared to TNBS treated group.

Dr. the lead authors in the joint study suggested that the study depicted a significant amelioration in the TNBS- and EGCG-treated rats compared to the non-treated animals in similar to histological data, as the mechanism of action occurred basically through the NF-kB pathway and possibly through crosstalk with other pathways.

Taken together, green tea and its bioactive polyphenols may be considered as functional foods for the prevention and treatment of ulcerative colitis through the expression of antioxidant and anti-inflammatory activity.

Intake of green tea extract should be taken with extreme care as acute toxicity has been reported in some cases.

https://kylejnorton.blogspot.com/2018/09/green-tea-beverage-which-blocks-onset.html



Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight

How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca



Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299



Sources
(1) A pilot study to evaluate the safety and efficacy of an oral dose of (-)-epigallocatechin-3-gallate-rich polyphenon E in patients with mild to moderate ulcerative colitis by Dryden GW1, Lam A, Beatty K, Qazzaz HH, McClain CJ. (PubMed)
(2) Tea catechins induce crosstalk between signaling pathways and stabilize mast cells in ulcerative colitis by Gerges Geagea A1,2, Rizzo M2, Eid A1, Hajj Hussein I3, Zgheib Z1, Zeenny MN1, Jurjus R4, Uzzo ML5, Spatola GF5, Bonaventura G5, Leone A5, Massaad-Massade L6,7,8, Jurjus A1.(PubMed)
(3) EGCG Maintains Th1/Th2 Balance and Mitigates Ulcerative Colitis Induced by Dextran Sulfate Sodium through TLR4/MyD88/NF-κB Signaling Pathway in Rats by TNBS,1 Liu Xuelei,2 Dong Wanwei,3 Liang Linlang,1 and Chen Keyan3(Hindawi)