Regular physical activity has long been found to associate to the prevention of cancer, cardiovascular disease, and other chronic diseases, but regular walking contribution of health benefits of reduced symptoms of Gout in the younger and older elderly have been lacking, due to caregivers and physicians prefer to emphasize, in most cases in reduced pain by prescribed medicine and intake of foods with rich of purines(4).
A Delphi exercise conducted by the University of Otago suggested that both physicians and patients agreed upon several key features of gout, including severity, functional results, and idiographic perception and patterns of symptoms(1).
Dr. Stewart S and colleagues at the joint study led by the Auckland University of Technology indicated the importance of footwear worn as walking shoes with good footwear characteristics can influence plantar pressure values and encourage a more efficient heel to toe gait pattern in people with gout(2)
The National Kidney foundation reminded, "some people with gout do not have high uric acid levels, so it is very important to maintain a healthy lifestyle no matter the level. Do not smoke, follow a well-balanced diet, maintain a healthy weight, and exercise"(5).
In fact, according to 2008 American Society for Clinical Nutrition, the risk of gout is lower in men who are more physically active, maintain ideal body weight, and consume diets enriched in fruit and limited in meat and alcohol(3). Unfortunately, exercise, including walking during a gout attack will worsen the condition by inducing more pain and lengthening the inflammation.
“Exercises to relieve gout should be done steady and cautiously as to avoid further irritation to the joints. The best exercises for gout are a range of motion types: strength training, stretching and building endurance. Yoga is an exercise that incorporates all four; however, there are other exercises that can be done individually also” According to the article of How to Exercise If You Have Gout(6).
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
References
(1) A delphi exercise to identify characteristic features of gout - opinions from patients and physicians, the first stage in developing new classification criteria by Prowse RL1, Dalbeth N, Kavanaugh A, Adebajo AO, Gaffo AL, Terkeltaub R, Mandell BF, Suryana BP, Goldenstein-Schainberg C, Diaz-Torne C, Khanna D, Lioté F, Mccarthy G, Kerr GS, Yamanaka H, Janssens H, Baraf HF, Chen JH, Vazquez-Mellado J, Harrold LR, Stamp LK, Van De Laar MA, Janssen M, Doherty M, Boers M, Edwards NL, Gow P, Chapman P, Khanna P, Helliwell PS, Grainger R,Schumacher HR, Neogi T, Jansen TL, Louthrenoo W, Sivera F, Taylor WJ, Alten R.(PubMed)
(2) The effect of good and poor walking shoe characteristics on plantar pressure and gait in people with gout by Stewart S1, Dalbeth N2, McNair P3, Parmar P4, Gow P5, Rome K3.(PubMed)
(3) Effects of diet, physical activity and performance, and body weight on incident gout in ostensibly healthy, vigorously active men1,2,3 by Paul T Williams(American Society for Clinical Nutrition)
(4)A case-control study of the association of diet and obesity with gout in Taiwan1,2,3 by Li-Ching Lyu, Chi-Yin Hsu, Ching-Ying Yeh, Meei-Shyuan Lee, Su-Hua Huang, and Ching-Lan Chen( American Society for Clinical Nutrition)
(5) GOUT AND HYPERURICEMIA(The national Kidney foundation)
(6) How to Exercise If You Have Gout(3fc)
Thursday, June 6, 2019
Whole Food Honey Speeds Up Wound Healing
The wound can be internal or external. It is a cut or open of skin or injury of tissues caused by the physical impacts.
Human all have the experience of an open wound at some point in their life. Most wounds are minor. However, if the opening wound that lasts more than 20 minutes and causes a loss of a large pool of blood can be an emergency.
Wounds can be classified into 4 types
* An abrasion is a wound caused by rubbing or scraping the skin against a rough or hard surface.
* A laceration is a cut or tearing of your skin in most cases caused by knives, tools accidentally.
* Puncture is a hole caused by a sharp object, due to its strong impact, puncture has been found to induce tissue damage
* An avulsion is the most serious case of wound that induces a partial or complete tearing away of skin and the tissue beneath.
Not all wounds are the same if the wound cause bleeding longer than 20 minutes and deeper than 1/2 inches, you have to go to the emergency right the way.
In some cases, longer wound bleeding is also associated with the intake of certain medications such as blood thinner.
Treatment of a wound in conventional medicine is to reduce pain and prevent infection. Do not expect the doctor to provide you with medicine that speeds up the wound healing.
Honey, the rich golden liquid is the miraculous product made by bees using nectar from flowers.
The liquid is considered one of the healthy food for replacing the use of white sugar and artificial sweetener by many people.
On finding natural products for speed-up wound healing, researchers examined the honey in the contribution to its beneficial properties, especially in the wound healing process.
Stingless bee honey exerted a significant activity in breaking down the chain of free radicals that cause a detrimental effect to the wounded area through its antioxidant property.
The stingless bee honey sped up wound healing by protecting the wound against bacterial contamination through its antimicrobial property.
Furthermore, the tested honey also protected the wound dealing process by inhibiting the inflammation induced cytotoxicity.
Moreover, the tested honey promoted angiogenesis and oxygen circulation by its moisturizing properties.
Based on the results, researchers wrote, "The application of honey to the wound has been widely used since ancient times. As a result, it is essential to understand the pharmacological mechanism of the honey towards the physiology of the wounded skin in order to optimize the healing rate in the future".
Additionally, in order to learn more information about honey wound healing effects, researchers evaluated the effects of honey in the healing of skin wounds and particularly chronic wounds, such as diabetic foot ulcers.
Amongst the five tested honey, BL1 and BL5 honey showed the most promising healing properties due to the presence of flavanol that is already known to possess interesting biological activities.
Taken altogether, honey processed a high amount of flavanol may be considered a functional remedies for the promotion of wound healing with no side effects, pending to the confirmation of large sample size and multicenter human study.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
References
(1) Stingless Bee Honey, the Natural Wound Healer: A Review by Abd Jalil MA1, Kasmuri AR, Hadi H. (PubMed)
(2) Evaluation of the In Vitro Wound-Healing Activity of Calabrian Honeys by Governa P1, Carullo G2, Biagi M3, Rago V4, Aiello F. (PubMed)
Human all have the experience of an open wound at some point in their life. Most wounds are minor. However, if the opening wound that lasts more than 20 minutes and causes a loss of a large pool of blood can be an emergency.
Wounds can be classified into 4 types
* An abrasion is a wound caused by rubbing or scraping the skin against a rough or hard surface.
* A laceration is a cut or tearing of your skin in most cases caused by knives, tools accidentally.
* Puncture is a hole caused by a sharp object, due to its strong impact, puncture has been found to induce tissue damage
* An avulsion is the most serious case of wound that induces a partial or complete tearing away of skin and the tissue beneath.
Not all wounds are the same if the wound cause bleeding longer than 20 minutes and deeper than 1/2 inches, you have to go to the emergency right the way.
In some cases, longer wound bleeding is also associated with the intake of certain medications such as blood thinner.
Treatment of a wound in conventional medicine is to reduce pain and prevent infection. Do not expect the doctor to provide you with medicine that speeds up the wound healing.
Honey, the rich golden liquid is the miraculous product made by bees using nectar from flowers.
The liquid is considered one of the healthy food for replacing the use of white sugar and artificial sweetener by many people.
On finding natural products for speed-up wound healing, researchers examined the honey in the contribution to its beneficial properties, especially in the wound healing process.
Stingless bee honey exerted a significant activity in breaking down the chain of free radicals that cause a detrimental effect to the wounded area through its antioxidant property.
The stingless bee honey sped up wound healing by protecting the wound against bacterial contamination through its antimicrobial property.
Furthermore, the tested honey also protected the wound dealing process by inhibiting the inflammation induced cytotoxicity.
Moreover, the tested honey promoted angiogenesis and oxygen circulation by its moisturizing properties.
Based on the results, researchers wrote, "The application of honey to the wound has been widely used since ancient times. As a result, it is essential to understand the pharmacological mechanism of the honey towards the physiology of the wounded skin in order to optimize the healing rate in the future".
Additionally, in order to learn more information about honey wound healing effects, researchers evaluated the effects of honey in the healing of skin wounds and particularly chronic wounds, such as diabetic foot ulcers.
Amongst the five tested honey, BL1 and BL5 honey showed the most promising healing properties due to the presence of flavanol that is already known to possess interesting biological activities.
Taken altogether, honey processed a high amount of flavanol may be considered a functional remedies for the promotion of wound healing with no side effects, pending to the confirmation of large sample size and multicenter human study.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
References
(1) Stingless Bee Honey, the Natural Wound Healer: A Review by Abd Jalil MA1, Kasmuri AR, Hadi H. (PubMed)
(2) Evaluation of the In Vitro Wound-Healing Activity of Calabrian Honeys by Governa P1, Carullo G2, Biagi M3, Rago V4, Aiello F. (PubMed)
Wednesday, June 5, 2019
Whole Food Ginger, the Stroke Prevention Functional Remedy
Stroke is a medical condition characterized by the death of brain cells as a result of inadequate of oxygen-rich blood flow.
In other words, stroke can be caused by either ischemia, due to lack of blood flow or hemorrhagia, due to bleeding.
A stroke is a medical emergency. Early intervention in most cases can minimize brain damage and potential complications.
According to the statistics, in the US, stroke is the leading cause of serious, long-term disability.
Each year, approximately 795,000 people suffer a stroke and recurrent stroke. Most cases of stroke are associated with adults over the age of 65.
Not all strokes can lead to permanent brain damage. Some people with a temporary disruption of blood flow to the brain do not result in permanent damage.
Besides aging, smoking, medical conditions such as unmanaged high blood pressure and cholesterol and diabetes, obesity, physical inactivity are some of the prevalent factors found in stroke patients.
Some researchers suggested a poor diet pattern such as the Western diet may have a strong impact in elevated the risk of stroke in the Western world.
Dr. Sherzai A, the lead scientist wrote, " Stroke is the fourth leading cause of mortality in the United States, yet it is 80% preventable by addressing lifestyle factors including nutrition".
And, "Adherence to DASH, Mediterranean, and prudent dietary patterns reduced the risk of stroke, whereas the Western dietary pattern was associated with increased stroke risk".
Ginger (Zingiber officinale) or ginger root, the second superfood used for thousands of years by mankind, is the genus Zingiber, belonging to the family Zingiberaceae, native to Tamil.
The root has been used in traditional and Chinese medicine for the treatment of dyspepsia, gastroparesis, constipation, edema, difficult urination, colic, etc.
With an aim to find a natural whole food for reducing the risk of stroke researchers examined the effects of ginger in the risk of stroke.
Three candidates from the ginger family identified based on the prediction models in the study were compared to those of the control inhibitor L-454560.
PDE4D inhibitor is a potential drug target used in stroke prevention.
Administration of 3 compounds identified from the ginger family was capable in inhibiting cAMP binding associated with the increase of stroke risk, similar to those of PDE4D.
Genetic polymorphisms of PDE4D (T83C, C87T, and C45T) gene is associated with increased risk of ischemic stroke (IS).
Genetic polymorphisms of ALOX5AP are also associated with ischemic stroke and atherothrombotic events in stroke patients.
In order to reveal more information about ginger anti-stroke risk activity, researchers examined the ginger on the activities of phosphodiesterase 4D (PDE4D) and 5-Lipoxygenase activating protein (ALOX5AP), the two of the major factors involved in the ischemic stroke, accounting for around 80-85% of total stroke.
Injection of ginger not only modulated the expression of PDE4D activities against the activation of cAMP-induced stroke and cardiovascular diseases but also inhibited the overexpression of ALOX5AP that could induce the development of atherosclerosis and stroke through inflammatory pathways.
Take all together, ginger may be considered a functional alternative for the prevention of stroke, pending to the confirmation of large sample size and multicenter human study.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma ISSN 0975-6299.
Sources
(1) In silico pharmacology suggests ginger extracts may reduce stroke risks by Chang TT1, Chen KC, Chang KW, Chen HY, Tsai FJ, Sun MF, Chen CY. (PubMed)
(2) Traditional Chinese medicine, a solution for reducing dual stroke risk factors at once? by Chen KC1, Chang KW, Chen HY, Chen CY. (PubMed)
(3) Stroke, food groups, and dietary patterns: a systematic review by Sherzai A1, Heim LT, Boothby C, Sherzai AD. (PubMed)
Regular Walking Reduces Risk and Complications of hyperlipidemia in Older Adults of 50+
Regular Walking of 30 to 60 minutes per session on 2 days per week for 12 weeks, according to the joint study led by the Dong-A University, not only lowered Plasma oxidized low-density lipoprotein concentrations but also improved the ratio of oxidized low-density lipoprotein to high-density lipoprotein cholesterol significantly in comparison t. o baseline ratio(3) of that induced the reduced risk of cardiovascular-related health in older adults.
Dr. Neuparth MJ and colleagues at the Universidade do Porto in the study of moderate walking exercise on reduced chemerin levels in Portuguese patients with type 2 diabetes said, " The active patients, compared with the inactive, presented a trend toward higher levels of adiponectin and lower values of oxidized low-density lipoprotein." and " moderate walking in a regular basis was sufficient to reduce chemerin levels(involved activation of inflammatory and coagulation serine proteases.)"(4).
Cardiovascular disease, a complication of high blood cholesterol kills more than 2,000 Americans every day. Approximately 60 million Americans have heart disease, according to statistic and literature, hyperlipidemia is a good document risk factor for Cardiovascular Disease(7).
The joint study led by the University of Porto, of prospective cohort analysis among 4207 US men and women of a mean age of 73 years(standard deviation=6) who were free of CVD at baseline in the Cardiovascular Health Study suggested, walking reduces the incidence of CVD among older adults(6).
In fact, regular walking, according to Dr.Bassuk SS and Dr. Manson JE. not only retarded the complications of high blood cholesterol or retard the progression of asymptomatic coronary and peripheral arteriosclerosis, but also improved cardioprotective mechanisms of physical activity include reducing adiposity, blood pressure, diabetes incidence, dyslipidemia, and inflammation, and enhancing insulin sensitivity, glycemic control, fibrinolysis, and endothelial function(5).
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
References
(1) Prevalence of Cholesterol Treatment Eligibility and Medication Use Among Adults--United States, 2005-2012 by Mercado C, DeSimone AK, Odom E, Gillespie C, Ayala C, Loustalot F.(PubMed)
(2) Vital signs: prevalence, treatment, and control of high levels of low-density lipoproteincholesterol--United States, 1999-2002 and 2005-200 by Centers for Disease Control and Prevention (CDC)(PubMed)
(3) Low-volume walking program improves cardiovascular-related health in older adults by Park JH1, Miyashita M2, Takahashi M3, Kawanishi N4, Hayashida H5, Kim HS6, Suzuki K3, Nakamura Y3.(PubMed)
(4) The positive effect of moderate walking exercise on chemerin levels in Portuguese patients with type 2 diabetes mellitus by Neuparth MJ1, Proença JB, Santos-Silva A, Coimbra S.(PubMed)
(5) Physical activity and the prevention of cardiovascular disease by Bassuk SS1, Manson JE.(PubMed)
(6) Physical Activity and Risk of Coronary Heart Disease and Stroke in Older Adults: The Cardiovascular Health Study by Soares-Miranda L1, Siscovick DS2, Psaty BM2, Longstreth WT Jr2, Mozaffarian D2.(PubMed)
(7) Hyperlipidemia as a Risk Factor for Cardiovascular Disease by Robert H. Nelson, MDa,b,(PMC)
Dr. Neuparth MJ and colleagues at the Universidade do Porto in the study of moderate walking exercise on reduced chemerin levels in Portuguese patients with type 2 diabetes said, " The active patients, compared with the inactive, presented a trend toward higher levels of adiponectin and lower values of oxidized low-density lipoprotein." and " moderate walking in a regular basis was sufficient to reduce chemerin levels(involved activation of inflammatory and coagulation serine proteases.)"(4).
Cardiovascular disease, a complication of high blood cholesterol kills more than 2,000 Americans every day. Approximately 60 million Americans have heart disease, according to statistic and literature, hyperlipidemia is a good document risk factor for Cardiovascular Disease(7).
The joint study led by the University of Porto, of prospective cohort analysis among 4207 US men and women of a mean age of 73 years(standard deviation=6) who were free of CVD at baseline in the Cardiovascular Health Study suggested, walking reduces the incidence of CVD among older adults(6).
In fact, regular walking, according to Dr.Bassuk SS and Dr. Manson JE. not only retarded the complications of high blood cholesterol or retard the progression of asymptomatic coronary and peripheral arteriosclerosis, but also improved cardioprotective mechanisms of physical activity include reducing adiposity, blood pressure, diabetes incidence, dyslipidemia, and inflammation, and enhancing insulin sensitivity, glycemic control, fibrinolysis, and endothelial function(5).
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
References
(1) Prevalence of Cholesterol Treatment Eligibility and Medication Use Among Adults--United States, 2005-2012 by Mercado C, DeSimone AK, Odom E, Gillespie C, Ayala C, Loustalot F.(PubMed)
(2) Vital signs: prevalence, treatment, and control of high levels of low-density lipoproteincholesterol--United States, 1999-2002 and 2005-200 by Centers for Disease Control and Prevention (CDC)(PubMed)
(3) Low-volume walking program improves cardiovascular-related health in older adults by Park JH1, Miyashita M2, Takahashi M3, Kawanishi N4, Hayashida H5, Kim HS6, Suzuki K3, Nakamura Y3.(PubMed)
(4) The positive effect of moderate walking exercise on chemerin levels in Portuguese patients with type 2 diabetes mellitus by Neuparth MJ1, Proença JB, Santos-Silva A, Coimbra S.(PubMed)
(5) Physical activity and the prevention of cardiovascular disease by Bassuk SS1, Manson JE.(PubMed)
(6) Physical Activity and Risk of Coronary Heart Disease and Stroke in Older Adults: The Cardiovascular Health Study by Soares-Miranda L1, Siscovick DS2, Psaty BM2, Longstreth WT Jr2, Mozaffarian D2.(PubMed)
(7) Hyperlipidemia as a Risk Factor for Cardiovascular Disease by Robert H. Nelson, MDa,b,(PMC)
Tuesday, June 4, 2019
Turmeric Protects the Nerves Against the Onset of Diabetic Neuropathy
Diabetic neuropathy is a complication of patients with diabetes associated with nerves damage, ranging from pain and numbness in your legs and feet to problems with your digestive system.
Most cases of diabetic neuropathy are involved in diabetics who have a history of hyperglycemia caused by long-term high levels of glucose in the bloodstream, urinary tract, blood vessels, and heart.
Diabetic neuropathy can be classified into 4 main types, including.
* Peripheral neuropathy is the most common type of diabetic neuropathy, affecting the nerves that control the feet and legs first, followed by the hands and arms.
* The autonomic neuropathy that affects the nerves that control the heart, bladder, stomach, intestines, sex organs and eyes.
* Radiculoplexus neuropathy found mostly in older patients affects nerves that control the thighs, hips, buttocks or legs.
* Mononeuropathy, or focal neuropathy also found commonly in older patients affects the nerves that control the face, middle of the body (torso) or leg.
The exact causes of diabetic neuropathy are totally depending on the type of neuropathy. However, damage of nerves and blood vessels in the affected area has been found to induce by over time, uncontrolled high blood sugar.
In other words, diabetic neuropathy is preventable by keeping the blood glucose in the healthy range.
Dr. Michael Greger M.D. FACLM in the article "the best diet for diabetic neuropathy" wrote, "
(By examing) people eating different diets found that nine months or more on a strict plant-based diet appeared to remove the trans fat from their bodies (or at least their butts). Their pain, however, didn’t take nine months to get better—it got better in days".
In the explanation of the results, the researcher continued, "More likely, it was due to an improvement in blood flow. “[N]erve biopsies in diabetics with severe progressive neuropathy…have shown small vessel disease within the nerve.” There are blood vessels within our nerves that can get clogged up too. The oxygen levels in the nerves of diabetics were found to be lower than even the levels of de-oxygenated blood".
Turmeric is a perennial plant in the genus Curcuma, belonging to the family Zingiberaceae, native to tropical South Asia.
The herb has been used in traditional medicine as anti-oxidant, hypoglycemic, colorant, antiseptic, wound healing agent, and for the treatment of flatulence, bloating, and appetite loss, ulcers, eczema, inflammations, etc.
In the urgency to find a potential ingredient for the treatment of diabetic neuropathy researchers examined the turmeric antioxidant property, anti-inflammatory, CNS depressant effect, antibacterial and antifungal property.
According to the results of the experiment, turmeric inhibited the pathogenesis of diabetic neuropathy by improving the antioxidant in the reduction of the level of oxidative stress associated with the occurrence of the present complication.
Furthermore, turmeric also enhanced the anti-inflammatory and antibacterial activity against the spread of infection.
In other words, turmeric inhibited diabetic neuropathy through a number of mechanisms involved in the antioxidant, anti-inflammatory and antibacterial activity.
In order to review more information about turmeric effect, researchers investigated Nishamalaki (NA), a combination of Curcuma longa and Emblica officinalis in the prevention of diabetic neuropathy.
The study included diabetic neuropathy in type 2 diabetic Wistar rats under treatment of 12 weeks.
Selected rats were randomly divided into group I (Control) vehicle treated consists of 6 rats and
group II-VII Diabetic Control, NA low dose, NA High dose, Glibenclamide, Pioglitazone and Epalrestat respectively.
Diabetes-induced in 36 Wistar rats with Streptozotocin (STZ) (35mg/kg) intraperitoneally followed by High Fat High Fructose diet. After confirmation of the development of diabetes; rats divided into six groups as the aforementioned division.
Compared to other treatment groups, Nishamalaki (NA) not only controlled hyperglycemia and reduced lipid levels but also effectively prevented the development of diabetic neuropathy.
Taken altogether, turmeric used alone or combined with other herbal medicine may be considered supplements for the prevention of diabetic neuropathy, pending to the confirmation of the larger sample size and multicenter human study.
Intake of turmeric in the form of supplement should be taken with extreme care to prevent overdose acute liver toxicity.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Investigation of the utility of Curcuma caesia in the treatment of diabetic neuropathy by Grover M1, Shah K2, Khullar G3, Gupta J1, Behl T. (PubMed)
(2) Evaluation of Effect of Nishamalaki on STZ and HFHF Diet Induced Diabetic Neuropathy in Wistar Rats by Dawane JS1, Pandit VA2, Bhosale MS3, Khatavkar PS. (PubMed)(3) Best Diet for Diabetic Neuropathy. Written By Michael Greger M.D. FACLM on January 1st, 2019
Most cases of diabetic neuropathy are involved in diabetics who have a history of hyperglycemia caused by long-term high levels of glucose in the bloodstream, urinary tract, blood vessels, and heart.
Diabetic neuropathy can be classified into 4 main types, including.
* Peripheral neuropathy is the most common type of diabetic neuropathy, affecting the nerves that control the feet and legs first, followed by the hands and arms.
* The autonomic neuropathy that affects the nerves that control the heart, bladder, stomach, intestines, sex organs and eyes.
* Radiculoplexus neuropathy found mostly in older patients affects nerves that control the thighs, hips, buttocks or legs.
* Mononeuropathy, or focal neuropathy also found commonly in older patients affects the nerves that control the face, middle of the body (torso) or leg.
The exact causes of diabetic neuropathy are totally depending on the type of neuropathy. However, damage of nerves and blood vessels in the affected area has been found to induce by over time, uncontrolled high blood sugar.
In other words, diabetic neuropathy is preventable by keeping the blood glucose in the healthy range.
Dr. Michael Greger M.D. FACLM in the article "the best diet for diabetic neuropathy" wrote, "
(By examing) people eating different diets found that nine months or more on a strict plant-based diet appeared to remove the trans fat from their bodies (or at least their butts). Their pain, however, didn’t take nine months to get better—it got better in days".
In the explanation of the results, the researcher continued, "More likely, it was due to an improvement in blood flow. “[N]erve biopsies in diabetics with severe progressive neuropathy…have shown small vessel disease within the nerve.” There are blood vessels within our nerves that can get clogged up too. The oxygen levels in the nerves of diabetics were found to be lower than even the levels of de-oxygenated blood".
Turmeric is a perennial plant in the genus Curcuma, belonging to the family Zingiberaceae, native to tropical South Asia.
The herb has been used in traditional medicine as anti-oxidant, hypoglycemic, colorant, antiseptic, wound healing agent, and for the treatment of flatulence, bloating, and appetite loss, ulcers, eczema, inflammations, etc.
In the urgency to find a potential ingredient for the treatment of diabetic neuropathy researchers examined the turmeric antioxidant property, anti-inflammatory, CNS depressant effect, antibacterial and antifungal property.
According to the results of the experiment, turmeric inhibited the pathogenesis of diabetic neuropathy by improving the antioxidant in the reduction of the level of oxidative stress associated with the occurrence of the present complication.
Furthermore, turmeric also enhanced the anti-inflammatory and antibacterial activity against the spread of infection.
In other words, turmeric inhibited diabetic neuropathy through a number of mechanisms involved in the antioxidant, anti-inflammatory and antibacterial activity.
In order to review more information about turmeric effect, researchers investigated Nishamalaki (NA), a combination of Curcuma longa and Emblica officinalis in the prevention of diabetic neuropathy.
The study included diabetic neuropathy in type 2 diabetic Wistar rats under treatment of 12 weeks.
Selected rats were randomly divided into group I (Control) vehicle treated consists of 6 rats and
group II-VII Diabetic Control, NA low dose, NA High dose, Glibenclamide, Pioglitazone and Epalrestat respectively.
Diabetes-induced in 36 Wistar rats with Streptozotocin (STZ) (35mg/kg) intraperitoneally followed by High Fat High Fructose diet. After confirmation of the development of diabetes; rats divided into six groups as the aforementioned division.
Compared to other treatment groups, Nishamalaki (NA) not only controlled hyperglycemia and reduced lipid levels but also effectively prevented the development of diabetic neuropathy.
Taken altogether, turmeric used alone or combined with other herbal medicine may be considered supplements for the prevention of diabetic neuropathy, pending to the confirmation of the larger sample size and multicenter human study.
Intake of turmeric in the form of supplement should be taken with extreme care to prevent overdose acute liver toxicity.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Investigation of the utility of Curcuma caesia in the treatment of diabetic neuropathy by Grover M1, Shah K2, Khullar G3, Gupta J1, Behl T. (PubMed)
(2) Evaluation of Effect of Nishamalaki on STZ and HFHF Diet Induced Diabetic Neuropathy in Wistar Rats by Dawane JS1, Pandit VA2, Bhosale MS3, Khatavkar PS. (PubMed)(3) Best Diet for Diabetic Neuropathy. Written By Michael Greger M.D. FACLM on January 1st, 2019
Phytochemical Betanin, the Potent Anti Prostate Cancer Remedy
Prostate cancer is a medical condition associated with cell growth disorderly in the tissue of the prostate.
The prostate is a reproductive gland in men that have shape and size of a walnut located between the bladder and the penis found in front of the rectum.
The gland has a unique function in the making of prostate fluid, one of the components of semen.
Prostate cancer is one of the slowest growth of cancer in men. Prostate cancer may take years to develop before affecting the patients with symptoms.
Most cases of prostate cancer are found in older men. However,
The disease also affects men before the ages of 40.
Believe it or not, about 1 man in 9 will be diagnosed with prostate cancer during his lifetime. According to the statistics, about 6 cases in 10 are diagnosed in men aged 65 or older.
In the US, approximately 1,700,000 new cases are diagnosed every year. Prostate cancer also causes the death of 609,640 patients.
The 5-year survival rate for diagnosed at local or regional prostate cancer is nearly 100%.
Although there are many risk factors involved in the onset of the condition, some researchers suggested the widespread prostate cancer over the past few decades may correlate to the promotion of a high-fat diet in the US.
Dr. Amir Bagheri, the lead scientists in the cancer team wrote, "Prostate cancer is one of the most common types of cancer with a high mortality rate".
And, "After adjustment for potential confounders, a healthy dietary pattern was associated with decreased risk of prostate cancer (highest versus lowest tertile OR:0.24; 95% CI: 0.07-0.81; trend p: 0.025). An unhealthy dietary pattern was related to increased risk of prostate cancer(highest versus lowest tertile OR:3.4; 95% CI: 1.09-10.32; trend p: 0.037)".
The findings strongly suggested that men who follow the Western diet pattern are associated with an increased risk of prostate cancer compared to those who do not.
Betanin is phytochemicals in the class of red and yellow indole-derived pigments of Betacyanins, belonging to the group of Betalains, found abundantly in beets, chard, etc.
With an aim to find an effective compound for the treatment of prostate cancer, researchers compared the cytotoxic effect of the red beetroot extract with an anticancer drug, doxorubicin (Adriamycin) in the androgen-independent human prostate cancer cells (PC-3).
According to the tested assays, both doxorubicin and the beetroot extract exhibited similarly a dose-dependent cytotoxic effect in the two cancer cell lines.
The cytotoxicity of the beetroot extract was significantly lower when compared to doxorubicin, however, the extract continued to decrease the growth rate of the PC-3 cells by 3.7% in 3 days vs. 12.5% in 7 days at the concentration of 29 µg/ml, compared to those of doxorubicin, at the same concentration level.
In further analysis, researchers found that the anti-prostate cancer effects of beetroot extract were attributed to the presence of betanin, the major betacyanin constituent in the exhibition of cytotoxicity.
Dr. Kapadia GJ, the lead scientists suggested the beetroot extract (B) when used alone or in combination with doxorubicin (D) may process chemopreventive potentials to mitigate the toxic side-effects of the latter.
In order to reveal more information of red beetroot (Beta vulgaris L.) anti-cancer activity researchers examined the beetroot extract (B), approved by Food and Drug Administration and European Union as red food color E162 against cancers.
In pancreatic (PaCa), breast (MCF-7) and prostate (PC-3) tumor cells of human origin, D showed an overall positive reduction in drug concentration when combined with B in its cytotoxicity profile.
The synergistic cytotoxicity was best when the B:D ratio of 1:5 was used in PaCa cells at IC50, IC75, and IC90 dose levels.
The findings strongly supported the potential use of red beetroot extract-doxorubicin combination in treating human prostate cancer.
In other words, red beetroot extracts not only processed the potential to improve the anti-cancer effects of doxorubicin through reduced volume used in prostate cancer treatment but also inhibited the doxorubicin's adverse effects.
Taken altogether, betanin used alone or combined with other medicines may be considered supplements for the prevention and treatment of prostate cancer, pending to the confirmation of the larger sample size and multicenter human study.
Intake of betanin in the form of supplement should be taken with extreme care to prevent overdose acute liver toxicity.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Cytotoxic effect of the red beetroot (Beta vulgaris L.) extract compared to doxorubicin (Adriamycin) in the human prostate (PC-3) and breast (MCF-7) cancercell lines by Kapadia GJ1, Azuine MA, Rao GS, Arai T, Iida A, Tokuda H. (PubMed)
(2) Synergistic cytotoxicity of red beetroot (Beta vulgaris L.) extract with doxorubicin in human pancreatic, breast and prostate cancer cell lines by Kapadia GJ1, Rao GS, Ramachandran C, Iida A, Suzuki N, Tokuda H. (PubMed)
(3) Dietary patterns and risk of prostate cancer: a factor analysis study in a sample of Iranian men by Amir Bagheri, 1 , 2 Seyed Mostafa Nachvak, 1 ,* Mansour Rezaei, 3 Mozhgan Moravridzade, 1 , 2Mahmoudreza Moradi, 4 and Michael Nelson. (PMC)
The prostate is a reproductive gland in men that have shape and size of a walnut located between the bladder and the penis found in front of the rectum.
The gland has a unique function in the making of prostate fluid, one of the components of semen.
Prostate cancer is one of the slowest growth of cancer in men. Prostate cancer may take years to develop before affecting the patients with symptoms.
Most cases of prostate cancer are found in older men. However,
The disease also affects men before the ages of 40.
Believe it or not, about 1 man in 9 will be diagnosed with prostate cancer during his lifetime. According to the statistics, about 6 cases in 10 are diagnosed in men aged 65 or older.
In the US, approximately 1,700,000 new cases are diagnosed every year. Prostate cancer also causes the death of 609,640 patients.
The 5-year survival rate for diagnosed at local or regional prostate cancer is nearly 100%.
Although there are many risk factors involved in the onset of the condition, some researchers suggested the widespread prostate cancer over the past few decades may correlate to the promotion of a high-fat diet in the US.
Dr. Amir Bagheri, the lead scientists in the cancer team wrote, "Prostate cancer is one of the most common types of cancer with a high mortality rate".
And, "After adjustment for potential confounders, a healthy dietary pattern was associated with decreased risk of prostate cancer (highest versus lowest tertile OR:0.24; 95% CI: 0.07-0.81; trend p: 0.025). An unhealthy dietary pattern was related to increased risk of prostate cancer(highest versus lowest tertile OR:3.4; 95% CI: 1.09-10.32; trend p: 0.037)".
The findings strongly suggested that men who follow the Western diet pattern are associated with an increased risk of prostate cancer compared to those who do not.
Betanin is phytochemicals in the class of red and yellow indole-derived pigments of Betacyanins, belonging to the group of Betalains, found abundantly in beets, chard, etc.
With an aim to find an effective compound for the treatment of prostate cancer, researchers compared the cytotoxic effect of the red beetroot extract with an anticancer drug, doxorubicin (Adriamycin) in the androgen-independent human prostate cancer cells (PC-3).
According to the tested assays, both doxorubicin and the beetroot extract exhibited similarly a dose-dependent cytotoxic effect in the two cancer cell lines.
The cytotoxicity of the beetroot extract was significantly lower when compared to doxorubicin, however, the extract continued to decrease the growth rate of the PC-3 cells by 3.7% in 3 days vs. 12.5% in 7 days at the concentration of 29 µg/ml, compared to those of doxorubicin, at the same concentration level.
In further analysis, researchers found that the anti-prostate cancer effects of beetroot extract were attributed to the presence of betanin, the major betacyanin constituent in the exhibition of cytotoxicity.
Dr. Kapadia GJ, the lead scientists suggested the beetroot extract (B) when used alone or in combination with doxorubicin (D) may process chemopreventive potentials to mitigate the toxic side-effects of the latter.
In order to reveal more information of red beetroot (Beta vulgaris L.) anti-cancer activity researchers examined the beetroot extract (B), approved by Food and Drug Administration and European Union as red food color E162 against cancers.
In pancreatic (PaCa), breast (MCF-7) and prostate (PC-3) tumor cells of human origin, D showed an overall positive reduction in drug concentration when combined with B in its cytotoxicity profile.
The synergistic cytotoxicity was best when the B:D ratio of 1:5 was used in PaCa cells at IC50, IC75, and IC90 dose levels.
The findings strongly supported the potential use of red beetroot extract-doxorubicin combination in treating human prostate cancer.
In other words, red beetroot extracts not only processed the potential to improve the anti-cancer effects of doxorubicin through reduced volume used in prostate cancer treatment but also inhibited the doxorubicin's adverse effects.
Taken altogether, betanin used alone or combined with other medicines may be considered supplements for the prevention and treatment of prostate cancer, pending to the confirmation of the larger sample size and multicenter human study.
Intake of betanin in the form of supplement should be taken with extreme care to prevent overdose acute liver toxicity.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Cytotoxic effect of the red beetroot (Beta vulgaris L.) extract compared to doxorubicin (Adriamycin) in the human prostate (PC-3) and breast (MCF-7) cancercell lines by Kapadia GJ1, Azuine MA, Rao GS, Arai T, Iida A, Tokuda H. (PubMed)
(2) Synergistic cytotoxicity of red beetroot (Beta vulgaris L.) extract with doxorubicin in human pancreatic, breast and prostate cancer cell lines by Kapadia GJ1, Rao GS, Ramachandran C, Iida A, Suzuki N, Tokuda H. (PubMed)
(3) Dietary patterns and risk of prostate cancer: a factor analysis study in a sample of Iranian men by Amir Bagheri, 1 , 2 Seyed Mostafa Nachvak, 1 ,* Mansour Rezaei, 3 Mozhgan Moravridzade, 1 , 2Mahmoudreza Moradi, 4 and Michael Nelson. (PMC)
Monday, June 3, 2019
Herbal Artichoke Regulates Insulinemic Response
Insulin response is a process of your body that react to the dietary intake.
Insulin produced by the pancreas is a hormone that binds the insulin receptors in the promotion of cell of the intestines to convert glucose to energy for the body needs.
Acute insulin response used as the predictor of types 2 diabetes by diagnosed both normal fasting and 2-h plasma glucose concentrations.
Compared to a healthy individual with normal insulin response, most patients of prediabetes and diabetes have elevated fasting and 2 hours of plasma glucose concentration.
There are many risk factors associated with the abnormal insulinemic response. However, some researchers suggested that the gradual dying of the beta cells of pancreas and insulin receptors sites clogging-up by cholesterol are 2 of the major causes that affect the insulin expression.
Some researchers suggested that abnormal insulin response may be correlated to the widespread of obesity that leads to insulin resistance in the Western world.
Dr. Olga T. Hardy, in the evaluation of the causes of insulin resistance underlying obesity wrote,
"The association between obesity and insulin resistance is an area of much interest and enormous public health impact".
And, "Visceral adiposity is correlated with the accumulation of excess lipid in the liver and results in cell-autonomous impairment in insulin signaling. Visceral adipose tissue is also prone to inflammation and inflammatory cytokine production, which also contribute to impairment in insulin signaling".
The results strongly suggested if you are obese, your risk of insulin resistance increased substantially compared to overweight or healthy weight individuals.
Artichoke is a perennial thistle of Cynara cardunculus species of the Cynara genus, belonging to the family Carduoideae native to Southern Europe around the Mediterranean.
The herbal plant has been used in traditional medicine as liver protective and detoxified agent, and to treat digestive disorders, abdominal pain gas and bloating, etc.
Researchers on finding a potential natural ingredient for the modulation of insulinemic response, researchers investigate the impact of the supplementation of a pre-biotic compound [Jerusalem artichoke meal (JAM)] on the glycaemic and insulinemic response in healthy, non-obese warm-blooded horses.
The study included 6 adult mares fed with crushed oat grains (1 g starch/kg bwt per day) and meadow hay (2 kg/100 kg bwt per day) together with either 0.15 g fructooligosaccharides and inulin (FOS+INU)/kg bwt per day via commercial JAM or maize cob meal without grains as control (CON) in 2 × 3-week periods according to a crossover design.
According to the sample collected at the postprandial (PP) time points (-60, 0, 30, 60, 90, 120, 180, 240 and 300 min), and the plasma glucose and serum insulin levels, JAM vs. CON did not change the PP peak of glucose or insulin (glucose: 6.3 ± 0.40 vs. 7.0 ± 0.87 mmol/l.
However, following JAM feeding, glucose and insulin levels declined more rapidly until 240 min PP compared to animal fed with CON.
The finding suggested that JAM exerted a significant effect on postprandial (PP) glucose and insulin levels on and after the time points of 240 min.
Furthermore, in order to reveal more information JA insulinemic response, researchers compared the Jerusalem artichoke (Helianthus tuberosus Linne, HTL) and chungkookjang (CKJ; fermented soybeans) in energy and glucose metabolism.
The study included rats divided into partially pancreatectomized (Px) diabetic rats, and sham-operated non-diabetic control rats and all fed high-fat diets. Additionally, diabetic rats were sub-divided into an untreated diabetic control group and those fed with 5% HTL, 5% CKJ or 5% HTL+5% CKJ for 8 weeks. HTL+CKJ treatment reduced visceral fat without modulating energy intake compared to diabetic control.
According to the hyperinsulinemic euglycemic assay, rats treated HTL, HTL+CKJ showed an improvement in glucose tolerance, compared to the diabetic normal-control group.
CKJ and CKJ+HTL but not HTL, injection groups increased first and second phase insulin secretion compared to that of diabetic-control.
Moreover, the glucose infusion rates (mg/kg bw/min) and hepatic insulin sensitivity were increased and CKJ+HTL (13.5), but not HTL (9.4) or CKJ (9.5) alone, and HTL and CKJ+ HTL decreased hepatic glucose compared to diabetic control.
Dr. Yang HJ, the lead scientist wrote in the final report, "HTL and CKJ enhanced glucose tolerance in different manners, and exhibited partially additive and complementary effects by reversing insulin resistance and enhancing β-cell function in diabetic rats".
Taken altogether, artichoke used alone or combined with another herbal remedy may be considered functional food for the enhancement of insulinemic response against the onset of diabetes, pending to the validation of larger sample size and multicenter human study.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
References
(1) Glycaemic and insulinaemic responses of adult healthy warm-blooded mares following feeding with Jerusalem artichoke meal by Glatter M1, Bochnia M1, Goetz F1, Gottschalk J2, Koeller G3, Mielenz N4, Hillegeist D5, Greef JM5, Einspanier A2, Zeyner A. (PubMed)
(2) Jerusalem artichoke and chungkookjang additively improve insulin secretion and sensitivity in diabetic rats by Yang HJ1, Kwon DY, Kim MJ, Kang S, Kim DS, Park S. (PubMed)
(3) What causes the insulin resistance underlying obesity? by Olga T. Hardy, Michael P. Czech, and Silvia Corvera. (PMC)
Insulin produced by the pancreas is a hormone that binds the insulin receptors in the promotion of cell of the intestines to convert glucose to energy for the body needs.
Acute insulin response used as the predictor of types 2 diabetes by diagnosed both normal fasting and 2-h plasma glucose concentrations.
Compared to a healthy individual with normal insulin response, most patients of prediabetes and diabetes have elevated fasting and 2 hours of plasma glucose concentration.
There are many risk factors associated with the abnormal insulinemic response. However, some researchers suggested that the gradual dying of the beta cells of pancreas and insulin receptors sites clogging-up by cholesterol are 2 of the major causes that affect the insulin expression.
Some researchers suggested that abnormal insulin response may be correlated to the widespread of obesity that leads to insulin resistance in the Western world.
Dr. Olga T. Hardy, in the evaluation of the causes of insulin resistance underlying obesity wrote,
"The association between obesity and insulin resistance is an area of much interest and enormous public health impact".
And, "Visceral adiposity is correlated with the accumulation of excess lipid in the liver and results in cell-autonomous impairment in insulin signaling. Visceral adipose tissue is also prone to inflammation and inflammatory cytokine production, which also contribute to impairment in insulin signaling".
The results strongly suggested if you are obese, your risk of insulin resistance increased substantially compared to overweight or healthy weight individuals.
Artichoke is a perennial thistle of Cynara cardunculus species of the Cynara genus, belonging to the family Carduoideae native to Southern Europe around the Mediterranean.
The herbal plant has been used in traditional medicine as liver protective and detoxified agent, and to treat digestive disorders, abdominal pain gas and bloating, etc.
Researchers on finding a potential natural ingredient for the modulation of insulinemic response, researchers investigate the impact of the supplementation of a pre-biotic compound [Jerusalem artichoke meal (JAM)] on the glycaemic and insulinemic response in healthy, non-obese warm-blooded horses.
The study included 6 adult mares fed with crushed oat grains (1 g starch/kg bwt per day) and meadow hay (2 kg/100 kg bwt per day) together with either 0.15 g fructooligosaccharides and inulin (FOS+INU)/kg bwt per day via commercial JAM or maize cob meal without grains as control (CON) in 2 × 3-week periods according to a crossover design.
According to the sample collected at the postprandial (PP) time points (-60, 0, 30, 60, 90, 120, 180, 240 and 300 min), and the plasma glucose and serum insulin levels, JAM vs. CON did not change the PP peak of glucose or insulin (glucose: 6.3 ± 0.40 vs. 7.0 ± 0.87 mmol/l.
However, following JAM feeding, glucose and insulin levels declined more rapidly until 240 min PP compared to animal fed with CON.
The finding suggested that JAM exerted a significant effect on postprandial (PP) glucose and insulin levels on and after the time points of 240 min.
Furthermore, in order to reveal more information JA insulinemic response, researchers compared the Jerusalem artichoke (Helianthus tuberosus Linne, HTL) and chungkookjang (CKJ; fermented soybeans) in energy and glucose metabolism.
The study included rats divided into partially pancreatectomized (Px) diabetic rats, and sham-operated non-diabetic control rats and all fed high-fat diets. Additionally, diabetic rats were sub-divided into an untreated diabetic control group and those fed with 5% HTL, 5% CKJ or 5% HTL+5% CKJ for 8 weeks. HTL+CKJ treatment reduced visceral fat without modulating energy intake compared to diabetic control.
According to the hyperinsulinemic euglycemic assay, rats treated HTL, HTL+CKJ showed an improvement in glucose tolerance, compared to the diabetic normal-control group.
CKJ and CKJ+HTL but not HTL, injection groups increased first and second phase insulin secretion compared to that of diabetic-control.
Moreover, the glucose infusion rates (mg/kg bw/min) and hepatic insulin sensitivity were increased and CKJ+HTL (13.5), but not HTL (9.4) or CKJ (9.5) alone, and HTL and CKJ+ HTL decreased hepatic glucose compared to diabetic control.
Dr. Yang HJ, the lead scientist wrote in the final report, "HTL and CKJ enhanced glucose tolerance in different manners, and exhibited partially additive and complementary effects by reversing insulin resistance and enhancing β-cell function in diabetic rats".
Taken altogether, artichoke used alone or combined with another herbal remedy may be considered functional food for the enhancement of insulinemic response against the onset of diabetes, pending to the validation of larger sample size and multicenter human study.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
References
(1) Glycaemic and insulinaemic responses of adult healthy warm-blooded mares following feeding with Jerusalem artichoke meal by Glatter M1, Bochnia M1, Goetz F1, Gottschalk J2, Koeller G3, Mielenz N4, Hillegeist D5, Greef JM5, Einspanier A2, Zeyner A. (PubMed)
(2) Jerusalem artichoke and chungkookjang additively improve insulin secretion and sensitivity in diabetic rats by Yang HJ1, Kwon DY, Kim MJ, Kang S, Kim DS, Park S. (PubMed)
(3) What causes the insulin resistance underlying obesity? by Olga T. Hardy, Michael P. Czech, and Silvia Corvera. (PMC)
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