Insulin resistance (IR), one of metabolic syndrome, is a condition of failure of cellular normal response to the hormone insulin. Patients with insulin resistance are found to have a significant risk to develop type 2 diabetes(1)(2)(3) and Heart diseases(3).
Regular physical activity has long been found to associate with the prevention of cancer, cardiovascular disease, and other chronic diseases, but regular walking contribution of reduced risk of Insulin Resistance in the younger and older elderly have been lacking, probably due to the effectiveness of modern restrict diet(4) and psychological therapies(5) in syndrome controlling.
Recent study conducted by the Klinika za endokrinologiju, showed that 10 sessions--35 min session of walking on treadmill, intensity 60.8 +/- 5.7% (VO2)max, frequency 5 times a week), had had significant influence on the increased aerobic capacity and insulin sensitivity in the tested patients(7), as well as enhanced suppression of hepatic glucose production(8).
In the review of data of 278,989 people (111,524 males and 167,465 females) living in Chiba Prefecture who underwent consecutive medical check-ups in 2008 and 2009, Dr. Ashizawa E and colleagues at the Chiba Prefectural Institute of Public Health said, "In men, the odds of developing MetS were significantly lower for participants who exercised regularly ("walking fast," OR=0.88, 95% CI [0.83-0.93]; and "higher physical activity," 0.85, [0.80-0.90])"(6).
Brisk walking, a popular and readily attainable form of moderate intensity physical activity, is one of the best to suitable for the majority of individuals to improve metabolic syndrome (MetS) risk factors in overweight male subjects, according to the study by University of Tsukuba(10).
Indeed, reductions in walking reduce insulin sensitivity and insulin signaling through multiple cellular processes in glucose metabolism(9) of that induced risk of Insulin Resistance in the progression of type 2 diabetes and cardiovascular diseases.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
References
(1) Increase in homeostasis model assessment of insulin resistance (HOMA-IR) had a strong impact on the development of type 2 diabetes in Japanese individuals with impaired insulinsecretion: the Saku study by Morimoto A1, Tatsumi Y2, Soyano F3, Miyamatsu N1, Sonoda N1, Godai K1, Ohno Y4, Noda M5, Deura K3.(PubMed)
(2) Insulin sensitivity and insulin secretion determined by homeostasis model assessment and risk of diabetes in a multiethnic cohort of women: the Women's Health Initiative Observational Study by Song Y1, Manson JE, Tinker L, Howard BV, Kuller LH, Nathan L, Rifai N, Liu S.(PubMed)
(3) Correlation of Serum Lipoprotein Ratios with Insulin Resistance in Infertile Women with Polycystic Ovarian Syndrome: A Case Control Study by Ghaffarzad A1, Amani R2, Mehrzad Sadaghiani M3, Darabi M4, Cheraghian B5.(PubMed)
(4) Very low-carbohydrate diets in the management of diabetes revisited by Schofield GM, Henderson G1, Thornley S.(PubMed)
(5) A Randomized Controlled Trial to Prevent Depression and Ameliorate Insulin Resistance in Adolescent Girls at Risk for Type 2 Diabetes by Shomaker LB1,2,3, Kelly NR4,5,6, Pickworth CK4, Cassidy OL4,5, Radin RM4,5, Shank LM4,5, Vannucci A4,5, Thompson KA4, Armaiz-Flores SA4, Brady SM4, Demidowich AP4, Galescu OA4, Courville AB7, Olsen C8, Chen KY9, Stice E10, Tanofsky-Kraff M11,12, Yanovski JA13.(PubMed)
(6) Exploring the link between standard lifestyle questionnaires administered during specific medical check-ups and incidence of metabolic syndrome in Chiba Prefecture by Ashizawa E1, Katano S, Harada A, Yanagibori R, Kobayashi Y, Sato S, Eguchi H.(PubMed)
(7) [Effect of a two-week program of individually monitored physical activity on insulin resistancein obese non-insulin-dependent diabetics].[Article in Serbian] by Cizmić M1, Zivotić-Vanović M, Zivanić S, Dragojević R.(PubMed)
(8) Effects of 7 days of exercise training on insulin sensitivity and responsiveness in type 2 diabetes mellitus by Kirwan JP1, Solomon TP, Wojta DM, Staten MA, Holloszy JO.(PubMed)
(9) Lack of regular physical exercise or too much inactivity byThyfault JP1, Booth FW.(PubMed)
(10) Lifestyle-based physical activity intervention for one year improves metabolic syndrome in overweight male employees by Kim J1, Tanabe K, Yoshizawa Y, Yokoyama N, Suga Y, Kuno S.(PubMed)
Friday, June 14, 2019
Phytchoemical Alliin Gobbles Up Cancer Cells in Vivo with No Side Effects
Cancer is a class of disease caused by irregular cell growth in the tissue or organ associated with the alternation of cell DNA.
Most cancers at the early stage, due to the small size of the tumor are asymptomatic, However, as the cells continue to proliferation, at some points, the tumor may affect the nearby blood vessels and nerve cell leading to symptoms of severe pain and bleeding accompanied by the general symptoms shared by all cancers.
Most primary cancers at the advanced stage can also travel a distance away from the original site to infect other healthy tissues, leading to a secondary metastasis.
According to the statistics provided by the National Cancer Institute, based on 2011–2015 statistics. approximately, 439.2 per 100,000 men and women per year are diagnosed with cancer. The number of cancer deaths is 163.5 per 100,000 men and women per year, also based on 2011–2015 statistics.
Cancers are classified depending on the types of cells alternation
* Carcinoma
Carcinoma is a malignant tumor found in anywhere of epithelial tissues lining the cavities, surfaces of structures and glands.
* Sarcoma
Sarcoma is a type of cancer that arises from malignantly connective tissue cells originated from embryonic germ cells or bone, cartilage, and fat tissues and cells.
* Lymphoma and leukemia
Hematopoietic cells are multipotent stem cells that give rise to all types of the blood cell, including red blood cells, white blood cells, and platelets become cancerous.
* Germ cell tumor
The cancer is derived from pluripotent cells. In adults, these are most often found in the testicle and ovary, However, the cancer is more common in babies and young children.
* Blastoma
The cancer is derived from immature "precursor" or embryonic tissue. These are also most common in children.
Alliin (S-allyl-L-cysteine-S-oxide) is a phytochemical compound sulfoxide,. a derivative of the amino acid cysteine, belonging to the class of sulfur compounds, found abundantly in fresh garlic and onion.
With an aim to find a potential treatment of cancer with no side effect, researchers examined the protective effect of three garlic powder compared to that alliin.
Rat selected to the study were administered for 2 weeks with 5% garlic powder diet.
According to the comet assay, consumption of the different garlic powders induced a 35-60% reduction in DNA damage induced by N-nitrosodimethylamine (NDMA) in rat liver.
Compared to the other garlic powders increased alliin content of the garlic powder was associated strongly with a proportional decrease in NDMA induced DNA alteration.
In other words, alliin increased anti-liver cancer activity of garlic powder proportionally compared to normal garlic powders.
Interestingly, DNA damage induced by aflatoxin B1 in the liver or by 1,2-dimethylhydrazine in the colon were also decreased strongly by the three garlic powders but these decreases were not correlated to the alliin content of the garlic powder.
In other words, all phytochemical compounds found in the garlic powder must work together to augment the anti-cancer effect regardless of the content of the individual compound.
In the study of liver cancer induced by injections of 0.025 mg/kg body weight aflatoxin B1 (AFB1) in rats, researchers garlic powder decreased the appearance and size of hepatic GST-P foci associated with early markers of the liver cancer.
However, garlic containing the highest level of alliin showed a stronger effect in the protection of liver against the forming hepatic GST-P foci compared to the normal garlic powders.
Levels of alliin showed an inverse associated with the number and area of preneoplastic foci.
Garlic powder ingestion increased the activity of hepatic detoxified enzymes such as glutathione S-transferase and UDP glucuronosyltransferase with no modification of nifedipine oxidase activity.
Dr. Bergès R, the lead researchers said, "It is suggested that garlic partly exerts its anticarcinogenic effects through increasing enzymes involved in AFB1 detoxification. This study highlights the possibility of controlling the cultivation conditions to improve the chemopreventive efficacy of garlic".
Taken altogether, alliin may be considered supplements for the prevention and treatment of cancer with no side effect, pending to the confirmation of the larger sample size and multicenter human study.
Intake of alliin in the form of supplement should be taken with extreme care to prevent overdose acute liver toxicity.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Inhibition of carcinogen-induced DNA damage in rat liver and colon by garlic powders with varying alliin content by Singh V1, Belloir C, Siess MH, Le Bon AM. (PubMed)
(2) Comparison of the chemopreventive efficacies of garlic powders with different alliin contents against aflatoxin B1 carcinogenicity in rats by Bergès R1, Siess MH, Arnault I, Auger J, Kahane R, Pinnert MF, Vernevaut MF, le Bon AM. (PubMed)
Most cancers at the early stage, due to the small size of the tumor are asymptomatic, However, as the cells continue to proliferation, at some points, the tumor may affect the nearby blood vessels and nerve cell leading to symptoms of severe pain and bleeding accompanied by the general symptoms shared by all cancers.
Most primary cancers at the advanced stage can also travel a distance away from the original site to infect other healthy tissues, leading to a secondary metastasis.
According to the statistics provided by the National Cancer Institute, based on 2011–2015 statistics. approximately, 439.2 per 100,000 men and women per year are diagnosed with cancer. The number of cancer deaths is 163.5 per 100,000 men and women per year, also based on 2011–2015 statistics.
Cancers are classified depending on the types of cells alternation
* Carcinoma
Carcinoma is a malignant tumor found in anywhere of epithelial tissues lining the cavities, surfaces of structures and glands.
* Sarcoma
Sarcoma is a type of cancer that arises from malignantly connective tissue cells originated from embryonic germ cells or bone, cartilage, and fat tissues and cells.
* Lymphoma and leukemia
Hematopoietic cells are multipotent stem cells that give rise to all types of the blood cell, including red blood cells, white blood cells, and platelets become cancerous.
* Germ cell tumor
The cancer is derived from pluripotent cells. In adults, these are most often found in the testicle and ovary, However, the cancer is more common in babies and young children.
* Blastoma
The cancer is derived from immature "precursor" or embryonic tissue. These are also most common in children.
Alliin (S-allyl-L-cysteine-S-oxide) is a phytochemical compound sulfoxide,. a derivative of the amino acid cysteine, belonging to the class of sulfur compounds, found abundantly in fresh garlic and onion.
With an aim to find a potential treatment of cancer with no side effect, researchers examined the protective effect of three garlic powder compared to that alliin.
Rat selected to the study were administered for 2 weeks with 5% garlic powder diet.
According to the comet assay, consumption of the different garlic powders induced a 35-60% reduction in DNA damage induced by N-nitrosodimethylamine (NDMA) in rat liver.
Compared to the other garlic powders increased alliin content of the garlic powder was associated strongly with a proportional decrease in NDMA induced DNA alteration.
In other words, alliin increased anti-liver cancer activity of garlic powder proportionally compared to normal garlic powders.
Interestingly, DNA damage induced by aflatoxin B1 in the liver or by 1,2-dimethylhydrazine in the colon were also decreased strongly by the three garlic powders but these decreases were not correlated to the alliin content of the garlic powder.
In other words, all phytochemical compounds found in the garlic powder must work together to augment the anti-cancer effect regardless of the content of the individual compound.
In the study of liver cancer induced by injections of 0.025 mg/kg body weight aflatoxin B1 (AFB1) in rats, researchers garlic powder decreased the appearance and size of hepatic GST-P foci associated with early markers of the liver cancer.
However, garlic containing the highest level of alliin showed a stronger effect in the protection of liver against the forming hepatic GST-P foci compared to the normal garlic powders.
Levels of alliin showed an inverse associated with the number and area of preneoplastic foci.
Garlic powder ingestion increased the activity of hepatic detoxified enzymes such as glutathione S-transferase and UDP glucuronosyltransferase with no modification of nifedipine oxidase activity.
Dr. Bergès R, the lead researchers said, "It is suggested that garlic partly exerts its anticarcinogenic effects through increasing enzymes involved in AFB1 detoxification. This study highlights the possibility of controlling the cultivation conditions to improve the chemopreventive efficacy of garlic".
Taken altogether, alliin may be considered supplements for the prevention and treatment of cancer with no side effect, pending to the confirmation of the larger sample size and multicenter human study.
Intake of alliin in the form of supplement should be taken with extreme care to prevent overdose acute liver toxicity.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Inhibition of carcinogen-induced DNA damage in rat liver and colon by garlic powders with varying alliin content by Singh V1, Belloir C, Siess MH, Le Bon AM. (PubMed)
(2) Comparison of the chemopreventive efficacies of garlic powders with different alliin contents against aflatoxin B1 carcinogenicity in rats by Bergès R1, Siess MH, Arnault I, Auger J, Kahane R, Pinnert MF, Vernevaut MF, le Bon AM. (PubMed)
Thursday, June 13, 2019
Whole Food Ginger, an Antibiotic Alternative with No Side Effects, Scientists Say
Infectious diseases are a medical condition caused by pathogenic microorganisms, including bacteria, viruses, parasites or fungi.
Most cases of infectious diseases are contagious by spreading directly or indirectly, from one person to another.
In other words, if you kiss, or are coughed or sneezed on by an infectious person, you are at risk of developing the same infectious disease.
According to the statistic provided by the World Health Organization, 3 infectious diseases were ranked in the top ten causes of death worldwide in 2016.
More precisely, lower respiratory infections, diarrheal diseases, and tuberculosis induced 3.0 million, 1.4 million, and 1.3 million deaths, respectively.
Conventionally, most cases of infectious diseases except those caused by viruses are treated by antibiotics.
If you are currently taking one of the antibiotics for the treatment of infectious diseases, please make sure you know all the side effects for preventive measure.
Diagnosis of the type of bacteria that causes the disease in most cases is important for precisive targeting.
Ginger (Zingiber officinale) or ginger root, the second superfood used for thousands of years by mankind, is the genus Zingiber, belonging to the family Zingiberaceae, native to Tamil.
The root has been used in traditional and Chinese medicine for the treatment of dyspepsia, gastroparesis, constipation, edema, difficult urination, colic, etc.
Researchers on finding a natural compound as the antibiotic alternative for the treatment of infectious diseases with no side effects evaluated the antibacterial properties of Allium sativum (garlic) cloves and Zingiber officinale (ginger) rhizomes against multi-drug resistant clinical pathogens causing nosocomial infection.
The study included two crude garlic cloves and ginger rhizomes with 95% (v/v) ethanol tested against five gram-negative and two-gram positive multi-drug resistant bacterial isolates.
Application of the extracts showed significant inhibition against all tested isolates.
The highest inhibition zone of garlic (19.45 mm) was found in the Pseudomonas aeruginosa (P. aeruginosa), with the minimal inhibitory concentration as low as 67.00 µg/mL.
Based on the findings, researchers wrote in the final report, "Natural spices of garlic and ginger possess effective anti-bacterial activity against multi-drug clinical pathogens and can be used for prevention of drug-resistant microbial diseases and further evaluation is necessary".
Additionally, in order to know more information about the ginger antibacterial property, researchers also examined the antimicrobial potency of fresh, natural and commercial dried Allium sativum and Zingiber officinale extracts against seven local clinical bacterial isolates such as Escherichia coli.
Compared to garlic extract, chloroform and diethyl ether extracts of Z. officinale showed a greater zone of inhibition of tested pathogens except for P. aeruginosa and E. coli.
Furthermore, all extracts of A. sativum and Z. officinale have a strong antibacterial effect compared to recommended standard antibiotics through activity index.
The efficacy of ginger against bacterial infectious diseases was attributed to the presence of various phytochemicals such as tannins, phenols, alkaloids, steroids, and saponins.
Dr. the lead scientist said, "These findings provide new insights to use A. sativum and Z. officinale as potential plant sources for controlling pathogenic bacteria and potentially considered as cost-effective in the management of diseases and to the threat of drug resistance phenomenon".
Take all together, ginger processed a high amount of bioactive compounds may be considered an antibiotic alternative for prevention and treatment of bacterial infectious diseases, pending to the confirmation of large sample size and multicenter human study.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma ISSN 0975-6299.
Sources
(1) Biological activities of Allium sativum and Zingiber officinale extracts on clinically important bacterial pathogens, their phytochemical and FT-IR spectroscopic analysis by Awan UA1, Ali S1, Shahnawaz AM1, Shafique I1, Zafar A1, Khan MAR2, Ghous T3, Saleem A4, Andleeb S. (PubMed)
(2) Antibacterial effect of Allium sativum cloves and Zingiber officinale rhizomes against multiple-drug resistant clinical pathogens by Karuppiah P1, Rajaram S. (PubMed)
Most cases of infectious diseases are contagious by spreading directly or indirectly, from one person to another.
In other words, if you kiss, or are coughed or sneezed on by an infectious person, you are at risk of developing the same infectious disease.
According to the statistic provided by the World Health Organization, 3 infectious diseases were ranked in the top ten causes of death worldwide in 2016.
More precisely, lower respiratory infections, diarrheal diseases, and tuberculosis induced 3.0 million, 1.4 million, and 1.3 million deaths, respectively.
Conventionally, most cases of infectious diseases except those caused by viruses are treated by antibiotics.
If you are currently taking one of the antibiotics for the treatment of infectious diseases, please make sure you know all the side effects for preventive measure.
Diagnosis of the type of bacteria that causes the disease in most cases is important for precisive targeting.
Ginger (Zingiber officinale) or ginger root, the second superfood used for thousands of years by mankind, is the genus Zingiber, belonging to the family Zingiberaceae, native to Tamil.
The root has been used in traditional and Chinese medicine for the treatment of dyspepsia, gastroparesis, constipation, edema, difficult urination, colic, etc.
Researchers on finding a natural compound as the antibiotic alternative for the treatment of infectious diseases with no side effects evaluated the antibacterial properties of Allium sativum (garlic) cloves and Zingiber officinale (ginger) rhizomes against multi-drug resistant clinical pathogens causing nosocomial infection.
The study included two crude garlic cloves and ginger rhizomes with 95% (v/v) ethanol tested against five gram-negative and two-gram positive multi-drug resistant bacterial isolates.
Application of the extracts showed significant inhibition against all tested isolates.
The highest inhibition zone of garlic (19.45 mm) was found in the Pseudomonas aeruginosa (P. aeruginosa), with the minimal inhibitory concentration as low as 67.00 µg/mL.
Based on the findings, researchers wrote in the final report, "Natural spices of garlic and ginger possess effective anti-bacterial activity against multi-drug clinical pathogens and can be used for prevention of drug-resistant microbial diseases and further evaluation is necessary".
Additionally, in order to know more information about the ginger antibacterial property, researchers also examined the antimicrobial potency of fresh, natural and commercial dried Allium sativum and Zingiber officinale extracts against seven local clinical bacterial isolates such as Escherichia coli.
Compared to garlic extract, chloroform and diethyl ether extracts of Z. officinale showed a greater zone of inhibition of tested pathogens except for P. aeruginosa and E. coli.
Furthermore, all extracts of A. sativum and Z. officinale have a strong antibacterial effect compared to recommended standard antibiotics through activity index.
The efficacy of ginger against bacterial infectious diseases was attributed to the presence of various phytochemicals such as tannins, phenols, alkaloids, steroids, and saponins.
Dr. the lead scientist said, "These findings provide new insights to use A. sativum and Z. officinale as potential plant sources for controlling pathogenic bacteria and potentially considered as cost-effective in the management of diseases and to the threat of drug resistance phenomenon".
Take all together, ginger processed a high amount of bioactive compounds may be considered an antibiotic alternative for prevention and treatment of bacterial infectious diseases, pending to the confirmation of large sample size and multicenter human study.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma ISSN 0975-6299.
Sources
(1) Biological activities of Allium sativum and Zingiber officinale extracts on clinically important bacterial pathogens, their phytochemical and FT-IR spectroscopic analysis by Awan UA1, Ali S1, Shahnawaz AM1, Shafique I1, Zafar A1, Khan MAR2, Ghous T3, Saleem A4, Andleeb S. (PubMed)
(2) Antibacterial effect of Allium sativum cloves and Zingiber officinale rhizomes against multiple-drug resistant clinical pathogens by Karuppiah P1, Rajaram S. (PubMed)
Regular Walking Reduced Risk of Early Onset, Progression and Symptoms of Alzheimer's disease
Regular physical activity has long been found to associate with the prevention of cancer, cardiovascular disease, and other chronic diseases, but regular walking contribution of reduced risk and progression of Alzheimer's disease in the younger and older elderly patient have been lacking, probably due to in reversibility in disease controlling(1) and in most cases in older adults(2).
Alzheimer's destroys brain cells, causing problems with memory, thinking, and behavior severe enough to affect language communication, memory, lifelong hobbies or social life. Alzheimer's gets worse over time, and it is fatal, due to the progression of the formation of plaques and tangles.
Strengthening the immune system fights against inflammation, reduce high blood pressure, lower cholesterol levels and a healthy diet will help to prevent Alzheimer's disease(3).
A new study conducted by the São Paulo State University, multimodal exercise, including walking intervention on frontal cognitive functions and kinematic gait parameters may be effective to prevent the progression in patients with Alzheimer's disease(4).
According to a study of the performance of exercise program such as walking, of 134 ambulatory patients with mild to severe AD, significantly improved ability to perform activities of daily living (ADLs), physical performance, and nutritional and decreasing behavioral disturbance and depression in patients(5).
In support of regular walking in improvement of cognitive and physical function in AD patients, Dr. Vreugdenhil A and colleagues at the University of Tasmania, said, " participation in a community-based exercise program can improve cognitive and physical function and independence in ADL in people with Alzheimer's disease,.... under the supervision of their carer.(6),
In fact, regular walking in elderly exercise program also showed to slow the rate of functional deterioration in mild AD and reduce falls and disease progression(8) in patients suffering from advanced AD(7), a major concern of caregivers, through the improvement of balance performance(8).
Dr. Ryan SM and colleagues in the study of examined exercise-mediated effects on AD pathology, cognitive function, hippocampal neurogenesis and neuroinflammation in transgenic mouse models of AD, concluded, "exercise presents a promising non-pharmacological option to potentially delay the onset of or slow down the progression of AD"(9) through " induced effects on hippocampal neurogenesis, cognitive function and neuroinflammation, and consider exercise as a potential pro-neurogenic and anti-inflammatory intervention for cognition"(10)
Some researches suggested that the effectiveness of exercise in delay the onset of or slow down the progression of AD by preventing amyloid-β (Aβ) load, probably are the results of exercise-induced protection against AD-related mitochondrial dysfunction and phenotypic deterioration(11).
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
References
(1) iPSCs: On the Road to Reprogramming Aging by Soria-Valles C1, López-Otín C2.(PubMed)
i(2) Clinical and cognitive trajectories in cognitively healthy elderly individuals with suspected non-Alzheimer's disease pathophysiology (SNAP) or Alzheimer's disease pathology: a longitudinal study BY Burnham SC1, Bourgeat P2, Doré V3, Savage G4, Brown B5, Laws S6, Maruff P7, Salvado O2, Ames D8, Martins RN9, Masters CL10,Rowe CC11, Villemagne VL12; AIBL Research Group.(PubMed)
(3) Regular Walking of 50+ to the World of Diseases Free and Longevity(Research and Studies) by Kyle J. Norton
(4) Multimodal exercise intervention improves frontal cognitive functions and gait in Alzheimer's disease: a controlled trial by Coelho FG1, Andrade LP, Pedroso RV, Santos-Galduroz RF, Gobbi S, Costa JL, Gobbi LT.(PubMed)
(5) Exercise program for nursing home residents with Alzheimer's disease: a 1-year randomized, controlled trial BY Rolland Y1, Pillard F, Klapouszczak A, Reynish E, Thomas D, Andrieu S, Rivière D, Vellas B.(PubMed)
(6) A community-based exercise programme to improve functional ability in people withAlzheimer's disease: a randomized controlled trial by Vreugdenhil A1, Cannell J, Davies A, Razay G.(PubMed)
(7) Effects of Exercise on Functional Performance and Fall Rate in Subjects with Mild or Advanced Alzheimer's Disease: Secondary Analyses of a Randomized Controlled Study by Öhman H1, Savikko N, Strandberg T, Kautiainen H, Raivio M, Laakkonen ML, Tilvis R, Pitkälä KH.(PubMed)
(8) Effectiveness of balance training exercise in people with mild to moderate severity Alzheimer's disease: protocol for a randomised trial by Hill KD1, LoGiudice D, Lautenschlager NT, Said CM, Dodd KJ, Suttanon P.(PubMed)
(9) Exercise as a pro-cognitive, pro-neurogenic and anti-inflammatory intervention in transgenic mouse models of Alzheimer's disease by Ryan SM1, Kelly ÁM2.(PubMed)
(10) Neuroinflammation negatively affects adult hippocampal neurogenesis and cognition: canexercise compensate? Ryan SM1, Nolan YM2.(PubMed)
(11) Exercise-induced neuroprotection of hippocampus in APP/PS1 transgenic mice via upregulation of mitochondrial 8-oxoguanine DNA glycosylase by Bo H1, Kang W2, Jiang N3, Wang X3, Zhang Y3, Ji LL4.(PubMed)
Alzheimer's destroys brain cells, causing problems with memory, thinking, and behavior severe enough to affect language communication, memory, lifelong hobbies or social life. Alzheimer's gets worse over time, and it is fatal, due to the progression of the formation of plaques and tangles.
Strengthening the immune system fights against inflammation, reduce high blood pressure, lower cholesterol levels and a healthy diet will help to prevent Alzheimer's disease(3).
A new study conducted by the São Paulo State University, multimodal exercise, including walking intervention on frontal cognitive functions and kinematic gait parameters may be effective to prevent the progression in patients with Alzheimer's disease(4).
According to a study of the performance of exercise program such as walking, of 134 ambulatory patients with mild to severe AD, significantly improved ability to perform activities of daily living (ADLs), physical performance, and nutritional and decreasing behavioral disturbance and depression in patients(5).
In support of regular walking in improvement of cognitive and physical function in AD patients, Dr. Vreugdenhil A and colleagues at the University of Tasmania, said, " participation in a community-based exercise program can improve cognitive and physical function and independence in ADL in people with Alzheimer's disease,.... under the supervision of their carer.(6),
In fact, regular walking in elderly exercise program also showed to slow the rate of functional deterioration in mild AD and reduce falls and disease progression(8) in patients suffering from advanced AD(7), a major concern of caregivers, through the improvement of balance performance(8).
Dr. Ryan SM and colleagues in the study of examined exercise-mediated effects on AD pathology, cognitive function, hippocampal neurogenesis and neuroinflammation in transgenic mouse models of AD, concluded, "exercise presents a promising non-pharmacological option to potentially delay the onset of or slow down the progression of AD"(9) through " induced effects on hippocampal neurogenesis, cognitive function and neuroinflammation, and consider exercise as a potential pro-neurogenic and anti-inflammatory intervention for cognition"(10)
Some researches suggested that the effectiveness of exercise in delay the onset of or slow down the progression of AD by preventing amyloid-β (Aβ) load, probably are the results of exercise-induced protection against AD-related mitochondrial dysfunction and phenotypic deterioration(11).
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
References
(1) iPSCs: On the Road to Reprogramming Aging by Soria-Valles C1, López-Otín C2.(PubMed)
i(2) Clinical and cognitive trajectories in cognitively healthy elderly individuals with suspected non-Alzheimer's disease pathophysiology (SNAP) or Alzheimer's disease pathology: a longitudinal study BY Burnham SC1, Bourgeat P2, Doré V3, Savage G4, Brown B5, Laws S6, Maruff P7, Salvado O2, Ames D8, Martins RN9, Masters CL10,Rowe CC11, Villemagne VL12; AIBL Research Group.(PubMed)
(3) Regular Walking of 50+ to the World of Diseases Free and Longevity(Research and Studies) by Kyle J. Norton
(4) Multimodal exercise intervention improves frontal cognitive functions and gait in Alzheimer's disease: a controlled trial by Coelho FG1, Andrade LP, Pedroso RV, Santos-Galduroz RF, Gobbi S, Costa JL, Gobbi LT.(PubMed)
(5) Exercise program for nursing home residents with Alzheimer's disease: a 1-year randomized, controlled trial BY Rolland Y1, Pillard F, Klapouszczak A, Reynish E, Thomas D, Andrieu S, Rivière D, Vellas B.(PubMed)
(6) A community-based exercise programme to improve functional ability in people withAlzheimer's disease: a randomized controlled trial by Vreugdenhil A1, Cannell J, Davies A, Razay G.(PubMed)
(7) Effects of Exercise on Functional Performance and Fall Rate in Subjects with Mild or Advanced Alzheimer's Disease: Secondary Analyses of a Randomized Controlled Study by Öhman H1, Savikko N, Strandberg T, Kautiainen H, Raivio M, Laakkonen ML, Tilvis R, Pitkälä KH.(PubMed)
(8) Effectiveness of balance training exercise in people with mild to moderate severity Alzheimer's disease: protocol for a randomised trial by Hill KD1, LoGiudice D, Lautenschlager NT, Said CM, Dodd KJ, Suttanon P.(PubMed)
(9) Exercise as a pro-cognitive, pro-neurogenic and anti-inflammatory intervention in transgenic mouse models of Alzheimer's disease by Ryan SM1, Kelly ÁM2.(PubMed)
(10) Neuroinflammation negatively affects adult hippocampal neurogenesis and cognition: canexercise compensate? Ryan SM1, Nolan YM2.(PubMed)
(11) Exercise-induced neuroprotection of hippocampus in APP/PS1 transgenic mice via upregulation of mitochondrial 8-oxoguanine DNA glycosylase by Bo H1, Kang W2, Jiang N3, Wang X3, Zhang Y3, Ji LL4.(PubMed)
Wednesday, June 12, 2019
Regular Walking, Improves symptoms, QOL and reduces psychological stress on patients with Crohn's disease
Regular physical activity has long been found to associate to the prevention of cancer, cardiovascular disease, and other chronic diseases but guidelines to support an older adult in engagement in regular physical activity (PA) to improve patients with Crohn's disease are lacking.
Crohn's disease is an inflammatory bowel disease (IBD) affecting any part of the gastrointestinal tract from mouth to anus, as a result of adipocytokines and macrophage mediators in the perpetuated intestinal inflammatory process(4).
According to the University of Manitoba, regular walking may improve patients with Crohn's disease psychologically and physically without adversely affect disease activity(1).
In twelve subjects completed the 12-wk exercise program, all subjects showed statistically significant improvements after walking an average of 2.9 sessions/wk, at an average of 32.6 min/session, and for an average distance of 3.5 km/session(1).
Indeed, a low-intensity walking program from the University of Western Ontario also suggested that patients with Crohn's disease not only show improvement of quality of life without exacerbation in disease symptoms(2).
In a review also by the university of Western Ontario, although current pharmaceutical treatments are effective in controlling symptoms, patients continue to experience a reduced quality of life (QOL). CD patients engaged in physical activity. Exercise can benefit in decreased CD activity, reduced psychological stress and improved QOL(3).
In fact, regular walking enhance skeletal muscles in releasing biologically active myokines, exerting the direct anti-inflammatory effects and inhibiting the release of proinflammatory mediators from visceral fat of that showed to improve symptoms of Crohn's disease (CD)(4).
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
1. The effects of physical exercise on patients with Crohn's disease. by Loudon CP1, Corroll V, Butcher J, Rawsthorne P, Bernstein CN..
2. Low-intensity exercise improves quality of life in patients with Crohn's disease by Ng V1, Millard W, Lebrun C, Howard J.
3. Exercise and Crohn's disease: speculations on potential benefits by Ng V1, Millard W, Lebrun C, Howard J.
(4) The role of physical exercise in inflammatory bowel disease by Bilski J1, Brzozowski B2, Mazur-Bialy A1, Sliwowski Z3, Brzozowski T3.
Crohn's disease is an inflammatory bowel disease (IBD) affecting any part of the gastrointestinal tract from mouth to anus, as a result of adipocytokines and macrophage mediators in the perpetuated intestinal inflammatory process(4).
According to the University of Manitoba, regular walking may improve patients with Crohn's disease psychologically and physically without adversely affect disease activity(1).
In twelve subjects completed the 12-wk exercise program, all subjects showed statistically significant improvements after walking an average of 2.9 sessions/wk, at an average of 32.6 min/session, and for an average distance of 3.5 km/session(1).
Indeed, a low-intensity walking program from the University of Western Ontario also suggested that patients with Crohn's disease not only show improvement of quality of life without exacerbation in disease symptoms(2).
In a review also by the university of Western Ontario, although current pharmaceutical treatments are effective in controlling symptoms, patients continue to experience a reduced quality of life (QOL). CD patients engaged in physical activity. Exercise can benefit in decreased CD activity, reduced psychological stress and improved QOL(3).
In fact, regular walking enhance skeletal muscles in releasing biologically active myokines, exerting the direct anti-inflammatory effects and inhibiting the release of proinflammatory mediators from visceral fat of that showed to improve symptoms of Crohn's disease (CD)(4).
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
1. The effects of physical exercise on patients with Crohn's disease. by Loudon CP1, Corroll V, Butcher J, Rawsthorne P, Bernstein CN..
2. Low-intensity exercise improves quality of life in patients with Crohn's disease by Ng V1, Millard W, Lebrun C, Howard J.
3. Exercise and Crohn's disease: speculations on potential benefits by Ng V1, Millard W, Lebrun C, Howard J.
(4) The role of physical exercise in inflammatory bowel disease by Bilski J1, Brzozowski B2, Mazur-Bialy A1, Sliwowski Z3, Brzozowski T3.
Bromelain Speeds Up Skin Healing with No Side Effects
Skin healing is a natural process to reconstruct the skin back to its originated stage after skin damage.
Skin is a large organ in the human body which only protects our body against foreign invaders but also serves as a third detoxed system after the liver and kidney.
Skin healing is depending on the size of the wound, the small size can be healed quickly without using any medication. However, the large size wound in most cases is required stitches.
Similar to wound healing, at the acute phase of infection, the macrophages of the immune first line of defense stimulating the blood clot to cover the wound or cut and production of proinflammatory cytokines to destroy foreign invaders.
In this phase, patients may experience symptoms of skin redness, tender, and swelling around the wound or cut.
Depending on the size of a skin wound, the next overlap stage is broken blood vessels in the wound is repaired and new tissue is grown followed by the creation of collagen, the fibers that form the foundation for new tissue.
This process continues until the skin is stronger or back to the original form.
In the acute phase of infection, overproduction of pro-inflammatory cytokines induced by immune response may cause damage to healthy cells, leading scar forming.
Additionally, any interruption of these processed may induce the formation of scars.
Bromelain, a proteolytic enzyme found in pineapples (Ananas comosus) has been used in traditional medicine as inflammatory agent and to treat pains, strains, and muscle aches and pains and ease back pain and chronic joint pain, skin diseases, etc.
On finding a potential compound for speedup wound healing, researchers compared the structural integrity of bromelain (debridement enzyme) in the healing process.
The study included a combinational multiphasic delivery system that delivers biomolecules of bromelain through the fabrication of coaxial electrospinning of different biocompatible polymers.
In vitro, the fabricated scaffold delivery system sustained the release of debriding protease and its bioactive components in a timely fashion showed a significant effect in wound healing.
Furthermore, the fabricated scaffold used in debridement enzyme also promoted the wound healing process by its angiogenic potential through in vitro migration of endothelial cells and increased new capillaries from the existing blood vessel in response to wound healing.
Moreover, in vivo, studies also confirm the efficacy of the fabricated scaffold used in the delivery of bromelain.
Based on the findings, researchers said, "Our results, therefore, open up a new avenue for designing a bioactive combinational multiphasic delivery system to enhance wound healing".
In order to assess the role and clinical advantages of enzymatic debridement by a mixture of proteolytic enzymes enriched in Bromelain (Nexobrid®) on wound healing, researchers examined the mutual experience of applying enzymatic debridement in more than 500 adult and pediatric patients by the consensus panelists.
The statement included the answer of questions related to pain management and anesthesia, the timing of application, technique of application, after-intervention care, skin grafting after enzymatic debridement, blood loss, training strategies and learning curve and areas of future research needs.
According to the statements returned by the participant, 68 consensus statements, enzymatic debridement used showed a higher degree of consensus with a unanimous consensus in 88.2% of statements, and lowest degree of consensus of 70% in only 3 statements.
Taken altogether, bromelain used alone or combined with the multiphasic delivery system may be considered supplements for the speedup wound healing, pending to the confirmation of the larger sample size and multicenter human study.
Intake of bromelain in the form of supplement should be taken with extreme care to prevent overdose acute liver toxicity.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Eschar removal by bromelain based enzymatic debridement (Nexobrid®) in burns: An European consensus by Hirche C1, Citterio A2, Hoeksema H3, Koller J4, Lehner M5, Martinez JR6, Monstrey S3, Murray A7, Plock JA8, Sander F9, Schulz A10, Ziegler B11, Kneser U. (PubMed)
(2) Fabrication of core-shell nanofibers for controlled delivery of bromelain and salvianolic acid B for skin regeneration in wound therapeutics by Shoba E1, Lakra R, Syamala Kiran M, Korrapati PS. (PubMed)
Skin is a large organ in the human body which only protects our body against foreign invaders but also serves as a third detoxed system after the liver and kidney.
Skin healing is depending on the size of the wound, the small size can be healed quickly without using any medication. However, the large size wound in most cases is required stitches.
Similar to wound healing, at the acute phase of infection, the macrophages of the immune first line of defense stimulating the blood clot to cover the wound or cut and production of proinflammatory cytokines to destroy foreign invaders.
In this phase, patients may experience symptoms of skin redness, tender, and swelling around the wound or cut.
Depending on the size of a skin wound, the next overlap stage is broken blood vessels in the wound is repaired and new tissue is grown followed by the creation of collagen, the fibers that form the foundation for new tissue.
This process continues until the skin is stronger or back to the original form.
In the acute phase of infection, overproduction of pro-inflammatory cytokines induced by immune response may cause damage to healthy cells, leading scar forming.
Additionally, any interruption of these processed may induce the formation of scars.
Bromelain, a proteolytic enzyme found in pineapples (Ananas comosus) has been used in traditional medicine as inflammatory agent and to treat pains, strains, and muscle aches and pains and ease back pain and chronic joint pain, skin diseases, etc.
On finding a potential compound for speedup wound healing, researchers compared the structural integrity of bromelain (debridement enzyme) in the healing process.
The study included a combinational multiphasic delivery system that delivers biomolecules of bromelain through the fabrication of coaxial electrospinning of different biocompatible polymers.
In vitro, the fabricated scaffold delivery system sustained the release of debriding protease and its bioactive components in a timely fashion showed a significant effect in wound healing.
Furthermore, the fabricated scaffold used in debridement enzyme also promoted the wound healing process by its angiogenic potential through in vitro migration of endothelial cells and increased new capillaries from the existing blood vessel in response to wound healing.
Moreover, in vivo, studies also confirm the efficacy of the fabricated scaffold used in the delivery of bromelain.
Based on the findings, researchers said, "Our results, therefore, open up a new avenue for designing a bioactive combinational multiphasic delivery system to enhance wound healing".
In order to assess the role and clinical advantages of enzymatic debridement by a mixture of proteolytic enzymes enriched in Bromelain (Nexobrid®) on wound healing, researchers examined the mutual experience of applying enzymatic debridement in more than 500 adult and pediatric patients by the consensus panelists.
The statement included the answer of questions related to pain management and anesthesia, the timing of application, technique of application, after-intervention care, skin grafting after enzymatic debridement, blood loss, training strategies and learning curve and areas of future research needs.
According to the statements returned by the participant, 68 consensus statements, enzymatic debridement used showed a higher degree of consensus with a unanimous consensus in 88.2% of statements, and lowest degree of consensus of 70% in only 3 statements.
Taken altogether, bromelain used alone or combined with the multiphasic delivery system may be considered supplements for the speedup wound healing, pending to the confirmation of the larger sample size and multicenter human study.
Intake of bromelain in the form of supplement should be taken with extreme care to prevent overdose acute liver toxicity.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Eschar removal by bromelain based enzymatic debridement (Nexobrid®) in burns: An European consensus by Hirche C1, Citterio A2, Hoeksema H3, Koller J4, Lehner M5, Martinez JR6, Monstrey S3, Murray A7, Plock JA8, Sander F9, Schulz A10, Ziegler B11, Kneser U. (PubMed)
(2) Fabrication of core-shell nanofibers for controlled delivery of bromelain and salvianolic acid B for skin regeneration in wound therapeutics by Shoba E1, Lakra R, Syamala Kiran M, Korrapati PS. (PubMed)
Tuesday, June 11, 2019
Regular Walking Reduces Risk of high triglyceride level Significantly
Regular physical activity has long been found to associate with the prevention of cancer, cardiovascular disease, and other chronic diseases, the joint study led by Universidade Federal de Minas Gerais, showed that regular physical activity (PA) induces desirable changes in plasma levels of high- and low-density lipoproteins (HDL and LDL, respectively) and triglycerides (TG), important risk factors for cardiometabolic diseases(4).
But the regular walking contribution of reduced risk of high triglyceride level in the younger and older elderly have been lacking, probably due to the effectiveness of modern diet restriction(2)(3) in syndrome controlling.
High Levels of Triglyceride is a condition of high levels of fat found in the blood. The University of South Carolina study blood lipid and lipoprotein adaptations to exercise suggested, exercise, including brisk walking or jogging, induced energy expenditure is also associated with TC and LDL-C reductions(1).
Regular walking showed to benefit a reduction of body fat stores, endogenous insulin requirements, and food intake and improved the ability to eliminate cholesterol and triglyceride concentrations by increasing the plasma high-density lipoprotein fraction(6).
Dr. Durstine JL and colleagues at the University of South Carolina, said, "Plasma triglycerides reductions are often observed after exercise training regimens requiring energy expenditure" but the health issues would fair better with "a comprehensive medical management plan that optimizes pharmacologic, reduced dietary fat intake, weight loss, and exercise interventions"(5).
Cardiovascular disease, a complication of high blood cholesterol and triglyceride kills more than 2,000 Americans every day. Approximately 60 million Americans have heart disease, according to statistic and literature, hyperlipidemia is a good document risk factor for Cardiovascular Disease(7).
Regular Walking also is found to Reduces Risk of Complication of Heart Disease in patients high triglyceride level. A study of 14 obese middle-aged women, after 24 weeks in the exercise program, exhibited a significant reduction of weight, body fat, body mass index, waist circumference, systolic blood pressure, diastolic blood pressure, and triglycerides, whereas HDLC, a metabolic improvement factor, increased significantly(8).
Stanford University School of Medicine study of one hundred nineteen of the men and 112 of the women showed that regular exercise in overweight men and women is the best way to enhance the improvement in plasma lipoprotein levels, together with the adoption of a low-saturated-fat, low-cholesterol diet(9).
In support the effectiveness of regular walking in reduced levels of cholesterol and triglycerides, the study of a 10-week Nordic walking training program on the level of GH and LH in elderly women, insisted, regular walking significantly decrease total cholesterol, LDL cholesterol and triglycerides (all on a similar average by between 0.1 and 0.2%), creatine kinase (on average by 14%), lactate dehydrogenase (on average by 4%), C-reactive protein (on average by 24%), and body mass (on average by 5.7%) of that protect against menopause-related catabolic processes(10).
Taking all together, regular walking when used in conjunction with low-saturated-fat, low-cholesterol diet may promote a better result in a reduced level of triglycerides, and total cholesterol in compared with the baseline of all testing subjects.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
References
(1) Blood lipid and lipoprotein adaptations to exercise: a quantitative analysis. by Durstine JL1, Grandjean PW, Davis PG, Ferguson MA, Alderson NL, DuBose KD(PubMed)
(2) [Effects of intrauterine growth restriction and high-fat diet on serum lipid and transcriptional levels of related hepatic genes in rats].[Article in Chinese] by Chen LH1, Liang L, Zhu WF, Wang YM, Zhu JF.(PubMed)
(3) Dietary Interventions and Changes in Cardio-Metabolic Parameters in Metabolically Healthy Obese Subjects: A Systematic Review with Meta-Analysis by Stelmach-Mardas M1,2, Walkowiak J3.(PubMed)
(4) Physical Activity and Lipid Profile in the ELSA- Brasil Study.[Article in English, Portuguese] by Silva RC1, Diniz MF1, Alvim S2, Vidigal PG1, Fedeli LM3, Barreto SM1.(PubMed)
(5) Lipids, lipoproteins, and exercise by Durstine JL1, Grandjean PW, Cox CA, Thompson PD.(PubMed)
(6) Effects of a vigorous walking program on body composition, and carbohydrate and lipid metabolism of obese young men by Leon AS, Conrad J, Hunninghake DB, Serfass R.(PubMed)
(7) Hyperlipidemia as a Risk Factor for Cardiovascular Disease by Robert H. Nelson, MDa,b,(PMC)
(8) Effect of Walking Exercise on Changes in Cardiorespiratory Fitness, Metabolic Syndrome Markers, and High-molecular-weight Adiponectin in Obese Middle-aged Women by Kim DY1, Seo BD2, Kim DJ1.(PubMed)
(9) The effects on plasma lipoproteins of a prudent weight-reducing diet, with or without exercise, in overweight men and women by Wood PD1, Stefanick ML, Williams PT, Haskell WL.(PubMed)
(10) The effect of a 10-week Nordic walking training program on the level of GH and LH in elderly women by Hagner-Derengowska M1, Kałużny K2, Hagner W2, Plaskiewicz A2, Bronisz A3, Borkowska A1, Budzyński J4.(PubMed)
But the regular walking contribution of reduced risk of high triglyceride level in the younger and older elderly have been lacking, probably due to the effectiveness of modern diet restriction(2)(3) in syndrome controlling.
High Levels of Triglyceride is a condition of high levels of fat found in the blood. The University of South Carolina study blood lipid and lipoprotein adaptations to exercise suggested, exercise, including brisk walking or jogging, induced energy expenditure is also associated with TC and LDL-C reductions(1).
Regular walking showed to benefit a reduction of body fat stores, endogenous insulin requirements, and food intake and improved the ability to eliminate cholesterol and triglyceride concentrations by increasing the plasma high-density lipoprotein fraction(6).
Dr. Durstine JL and colleagues at the University of South Carolina, said, "Plasma triglycerides reductions are often observed after exercise training regimens requiring energy expenditure" but the health issues would fair better with "a comprehensive medical management plan that optimizes pharmacologic, reduced dietary fat intake, weight loss, and exercise interventions"(5).
Cardiovascular disease, a complication of high blood cholesterol and triglyceride kills more than 2,000 Americans every day. Approximately 60 million Americans have heart disease, according to statistic and literature, hyperlipidemia is a good document risk factor for Cardiovascular Disease(7).
Regular Walking also is found to Reduces Risk of Complication of Heart Disease in patients high triglyceride level. A study of 14 obese middle-aged women, after 24 weeks in the exercise program, exhibited a significant reduction of weight, body fat, body mass index, waist circumference, systolic blood pressure, diastolic blood pressure, and triglycerides, whereas HDLC, a metabolic improvement factor, increased significantly(8).
Stanford University School of Medicine study of one hundred nineteen of the men and 112 of the women showed that regular exercise in overweight men and women is the best way to enhance the improvement in plasma lipoprotein levels, together with the adoption of a low-saturated-fat, low-cholesterol diet(9).
In support the effectiveness of regular walking in reduced levels of cholesterol and triglycerides, the study of a 10-week Nordic walking training program on the level of GH and LH in elderly women, insisted, regular walking significantly decrease total cholesterol, LDL cholesterol and triglycerides (all on a similar average by between 0.1 and 0.2%), creatine kinase (on average by 14%), lactate dehydrogenase (on average by 4%), C-reactive protein (on average by 24%), and body mass (on average by 5.7%) of that protect against menopause-related catabolic processes(10).
Taking all together, regular walking when used in conjunction with low-saturated-fat, low-cholesterol diet may promote a better result in a reduced level of triglycerides, and total cholesterol in compared with the baseline of all testing subjects.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
References
(1) Blood lipid and lipoprotein adaptations to exercise: a quantitative analysis. by Durstine JL1, Grandjean PW, Davis PG, Ferguson MA, Alderson NL, DuBose KD(PubMed)
(2) [Effects of intrauterine growth restriction and high-fat diet on serum lipid and transcriptional levels of related hepatic genes in rats].[Article in Chinese] by Chen LH1, Liang L, Zhu WF, Wang YM, Zhu JF.(PubMed)
(3) Dietary Interventions and Changes in Cardio-Metabolic Parameters in Metabolically Healthy Obese Subjects: A Systematic Review with Meta-Analysis by Stelmach-Mardas M1,2, Walkowiak J3.(PubMed)
(4) Physical Activity and Lipid Profile in the ELSA- Brasil Study.[Article in English, Portuguese] by Silva RC1, Diniz MF1, Alvim S2, Vidigal PG1, Fedeli LM3, Barreto SM1.(PubMed)
(5) Lipids, lipoproteins, and exercise by Durstine JL1, Grandjean PW, Cox CA, Thompson PD.(PubMed)
(6) Effects of a vigorous walking program on body composition, and carbohydrate and lipid metabolism of obese young men by Leon AS, Conrad J, Hunninghake DB, Serfass R.(PubMed)
(7) Hyperlipidemia as a Risk Factor for Cardiovascular Disease by Robert H. Nelson, MDa,b,(PMC)
(8) Effect of Walking Exercise on Changes in Cardiorespiratory Fitness, Metabolic Syndrome Markers, and High-molecular-weight Adiponectin in Obese Middle-aged Women by Kim DY1, Seo BD2, Kim DJ1.(PubMed)
(9) The effects on plasma lipoproteins of a prudent weight-reducing diet, with or without exercise, in overweight men and women by Wood PD1, Stefanick ML, Williams PT, Haskell WL.(PubMed)
(10) The effect of a 10-week Nordic walking training program on the level of GH and LH in elderly women by Hagner-Derengowska M1, Kałużny K2, Hagner W2, Plaskiewicz A2, Bronisz A3, Borkowska A1, Budzyński J4.(PubMed)
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