Monday, July 1, 2019

Healthy Legume, Navy Bean Reduces Risk of Breast Cancer

The breast is the tissue overlying the chest muscles. in women, breasts are made of specialized tissue that produces milk (glandular tissue) and fatty tissue. The size of the women breast is totally determined by the amount of fat.

Breast cancer is a medical condition associated with alternation of cell DNA located either in the inner lining of milk ducts (Ductal carcinoma) or the lobules (Lobular carcinoma) that supply the ducts with milk.

Most cases of breast cancer start in the cells on the surface of the inner lining tissues of the breast before penetrating into deeper layers to form a tumor through cell cycle division.

According to the statistics provided by the American Cancer Society, in the U.S. approximately, 1 in 8 U.S. women (about 12%) will develop invasive breast cancer over the course of her lifetime.

In 2019, approximately 268,600 new cases of invasive breast cancer will be diagnosed in women in the U.S., along with 62,930 new cases of non-invasive (in situ) breast cancer.


Most common symptoms of the early stage of breast cancer are lump (mass) in the breast, a lump in the armpit (lymph nodes), nipple discharge (clear or bloody), inverted or retracted nipple, scaly or pitted skin on nipple persistent tenderness of the breast and unusual breast pain or discomfort.

If you experience some of the aforementioned symptoms, please check with your doctor to rule out the possibility.

The 5 years survival rate of breast cancer diagnosed at the early stage is closed to 100%.

At the advanced stage, patients may also experience additional symptoms of bone pain (Secondary tumors in the bone), shortness of breath (Secondary tumors in the lung), unintentional weight loss and drop in appetite (Secondary tumors in the liver) and headaches, neurological pain or weakness (Secondary tumors in the nervous system).


The small, white navy bean, also called pea bean or haricot, popular in both dry and green forms, is very popular in Britain and the US, native to Peru. It is now grown and consumed across the world, due to their numerous health benefits.

On finding a potential compound for the treatment of breast cancer, researchers evaluated the high dietary fiber intake and breast cancer risk, particularly in hormone receptor‐negative breast cancer.

According to the returned food frequency data of a population‐based case–control study, including 2135 breast cancer cases (1070 Hispanics, 493 African Americans, and 572 non‐Hispanic Whites (NHWs)) and 2571 controls (1391 Hispanics, 557 African Americans, and 623 NHWs), high intake of bean fiber and total bean, including the navy bean reduced risk of breast cancer by 20% compared to those in the low quartile.

Furthermore, high intake of bean fiber and total bean have a strong inverse association with ER‐PR‐ breast cancer. More precisely, the reduced risk of ER-PR breast cancer associated with high intake were ranging from 28 to 36%.

Believe it or not, fiber intake from vegetables and fruits or total intake of vegetables and fruits showed no effects on the reduced risk of the diseases.

In other words, adding a portion or 2 of the navy bean into your daily diet may have a significant effect in the prevention of breast cancer, particularly in hormone-related breast cancer

Based on the finding, researchers wrote in the final report, "A high dietary intake of bean fiber and fiber‐rich foods such as beans and grains may lower the risk of ER‐PR‐ breast cancer, an aggressive breast cancer subtype for which few risk factors have been identified".

Taken altogether, navy bean containing a high amount of fibers may be considered a remedy for the prevention and treatment of hormone-related breast cancer pending to the confirmation of the larger sample size and multicenter human study.

Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight

How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca


Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.

Sources
(1) Intake of bean fiber, beans, and grains and reduced risk of hormone receptor‐negative breast cancer: the San Francisco Bay Area Breast Cancer Study by Meera Sangaramoorthy, 1 Jocelyn Koo, 1 and Esther M. John. (PMC)
(2) Breast Cancer by Kyle J. Norton

Sunday, June 30, 2019

Green tea, the Best Anti Depression Functional Whole Food

Green tea is found to consist of a psychological effect in patients with depression, a renowned institute study suggested

Depression is a normal response as part of our daily lives such as the loss of s job, the death of a loved one, and illness, affecting the way you eat, sleep, and the way you feel about yourself. Over 30 million Americans suffer from depression and the amount is increasing at an alarming rate.



Green tea, a precious drink processes numbers of health benefit known to almost everyone in Asia and Western world. However, as yin in nature herbal medicine or food, long term injection of large amounts may obstruct the balance of yin-yang, induced "yin excessive syndrome" or "yang vacuity syndrome" including weaken immunity and painful case of GERD,... according to traditional Chinese medicine's Yin-Yang theory.

In a cross-sectional study of consumption of green tea and coffee ascertained with a validated dietary questionnaire and the amount of caffeine intake estimated from these beverages, green tea consumption is associated to reduce symptoms of depression, depending to amount of intake.

In comparison to amount intake of participants, the study also found that participants consumed ≥4 cups green tea/d had a 51% significantly lower prevalence odds of having depressive symptoms than those consumed less than 1 cup/d.

Dr. Pham NM, the lead author in the study said, "higher consumption of green tea, coffee and caffeine may confer protection against depression".

In vivo, green tea(GT) and GABA green tea (GGT) also expressed a protective activity of against post-stroke depression (PSD), a common consequence of stroke, according to joint study lead by the Pavia University.

In a mouse model of post-stroke depression, GGT and GT enhance the activity in the modulation of depressive symptoms through decrease oxidative stress, increased antioxidant endogenous defenses, including polyphenol, theanine, glutamine, etc......

Furthermore, in the review of Embase, PubMed, and Chinese National Knowledge Infrastructure databases from their inception through August 2014, tea consumption of more than 3 cups a day showed a significant decrease in the risk of depression of 37% (RR = 0.63, 95% CI: 0.55-0.71), in compared to individuals with lower tea consumption and those with higher tea consumption.

Taking together, there is no doubt, green tea may be used as a functional food in reduced symptoms and risk of depression if consumes daily. However, oral administration of large amount daily should be taken with care, particular to people with yin constituent.


Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight

How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca


Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.

Sources
(1) Green tea and coffee consumption is inversely associated with depressivesymptoms in a Japanese working population by Pham NM1, Nanri A1, Kurotani K1, Kuwahara K1, Kume A1, Sato M2, Hayabuchi H3, Mizoue T1.(PubMed)
(2) Antidepressive-like effects and antioxidant activity of green tea and GABA green tea in a mouse model of post-stroke depression by Di Lorenzo A1, Nabavi SF2, Sureda A3, Moghaddam AH4, Khanjani S4, Arcidiaco P5, Nabavi SM2, Daglia M1.(PubMed)
(3) Effect of green tea on reward learning in healthy individuals: a randomized, double-blind, placebo-controlled pilot study by Zhang Q1, Yang H, Wang J, Li A, Zhang W, Cui X, Wang K.(PubMed)

Phytochemical Lycopene Exhibits Anti Cancer Angiogenesis

Angiogenesis is a process involved in the migration, growth, and differentiation of endothelial cells, that stimulates the growth of new blood vessel from the existing vessel.

Cancer is a class of diseases associated with abnormal cell growth due to the alternation of DNA.

Most cases of cancer begin in the cells on the surface of the inner lining of tissue. At the early stage, due to the small size of the tumor, most patients are asymptomatic. However, at the advanced stage, the oversize tumor can press on the nearby nerve cells and blood vessel, leading to bleeding and localized pain and symptoms accompanied by the general symptoms shared by other types of cancer, such as unintended weight loss.

Localized symptoms are totally depending on the types of cancer.

At this stage, cancer cells can also travel a distance away from the originated site to infect other healthy cells and tissue, causing a secondary metastasis.


Under normal conditions, angiogenesis is necessary for wound healing, tissues repairment in which the developing or healing tissues receive an adequate supply of nutrients.

In Cancer, angiogenesis induced the formation of new blood supply from the preexisting vasculature by false signaling in ensuring the tumor survive and propagate.


In other words, if we can cut off the energy supply to cancer which totally relyed to the formation of the new blood vessel for proliferation and expansion, we may cure those types of cancer.

Dr. Benouchan M, the lead scientist wrote, " tumor angiogenesis plays an important role in tumor development, vascular invasion, and hematogenous metastasis. Thus, anti-angiogenic therapy directed against tumor ECs should, in principle, improve the efficacy of antitumor therapy by inducing little or no drug resistance".

Lycopene is a phytochemical in the class of carotenoid, a natural pigment with no vitamin A activity found abundantly in tomatoes and other red fruits and vegetables, such as red carrots, watermelons, and papayas,

Tomatoes provide about 80% of the lycopene in the world diet. In plants, lycopene protects the host against excessive photodamage and performs various functions in photosynthesis.

With an aim to find a potent compound which processes anti-angiogenetic activity against cancer proliferation and invasion, researchers examined the apo-10'-lycopenoic acid (ALA), a derivative of lycopene on liver and lung cancer animal models.

In both Transwell and wound-healing models, application ALA in a dose-dependent manner was effective in inhibiting migration and invasion of liver and lung cancer cells.


Furthermore, ALA treatment suppressed the actin remodeling in orchestrating cancer cell motility and cancer cell membrane formation.

Moreover, the ALA also constrain the cancer proliferation, invasion by suppressing angiogenesis.

Based on the findings, researchers wrote, "ALA inhibits cancer cell motility and angiogenesis".

Dr. Zu K, the lead scientist in a joint study examined the effect of lycopene on tissue biomarkers in prostate cancers by analyzing the information obtained through questionnaires and ascertained total and lethal prostate cancer cases from 1986 through January 31, 2010, among 49898 male health professionals found that
* Higher lycopene intake was inversely associated with total prostate cancer and more strongly with lethal prostate cancer.

* Higher lycopene intake was associated with biomarkers in cancer indicative of less angiogenic potential.

In other words, higher lycopene intake reduced cancer proliferation by stimulating the formation of the new blood vessel.

Taken altogether, lycopene may be considered anti-angiogenetic supplements for the prevention and treatment of cancer through its anti-angiogenetic activity, pending on the confirmation of the larger sample size and multicenter human study.

Intake of lycopene in the form of supplement should be taken with extreme care to prevent overdose acute liver toxicity.

Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight

How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca


Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.

Sources
(1) Apo-10'-lycopenoic acid inhibits cancer cell migration and angiogenesis and induces peroxisome proliferator-activated receptor γ by Cheng J1, Miao B1, Hu KQ1, Fu X1, Wang XD. (PubMed)
(2) Dietary lycopene, angiogenesis, and prostate cancer: a prospective study in the prostate-specific antigen era by Zu K1, Mucci L, Rosner BA, Clinton SK, Loda M, Stampfer MJ, Giovannucci E. (PubMed)
(3) Anti-angiogenic strategies for cancer therapy (Review) by Benouchan M1, Colombo BM. (PubMed)

Saturday, June 29, 2019

Green Tea, the Best in Completed clearance of External Anogenital Warts Topically

Topical green tea extract may have a significant potency for treatment of External Anogenital Wartsis, a renowned institute study suggested

Green tea, a precious drink processes numbers of health benefit known to almost everyone in Asia and Western world. However, as yin in nature herbal medicine or food, long term injection of large amounts may obstruct the balance of yin-yang, induced "yin excessive syndrome" or "yang vacuity syndrome" including weaken immunity and painful case of GERD,... according to traditional Chinese medicine's Yin-Yang theory.

Catephen (Kora Corporation Ltd), is a herbal medicinal topical formulated product isolated from green tea, approved by the Medicines and Healthcare products Regulatory Agency (MHRA) inhibited the progression and cured external genital and perianal warts with 0.1g of green tea extract per gram (10%).

According to the University of Toronto, Sinecatechins ointment with 10% green tea extract also promoted quality of life and sexual well-being by healing the external genital warts (EGWs) induced by the human papilloma virus (HPV) cause of common sexually transmitted infection.


Dr. Gupta AK, the lead author said, " (The) phase III trials of sinecatechins 10% ointment have demonstrated higher efficacy and lower recurrence rates compared to currently available patient-applied treatments".

In a randomized, double-blind, vehicle-controlled trial involved 502 male and female patients aged 18 years and older, with 2-30 anogenital warts ranging from 12 to 600 mm(2) total wart area with topical application of sinecatechins ointment 15% or 10%, three times daily for a maximum of 16 weeks or until complete clearance of all warts or placebo, group treated with sinecatechins ointment at the end showed a partial clearance rates of at least of 78.4% and 74.0% compared with 51.5% in placebo, in the week 4 and 6.

The study also found that sinecatechins ointment group also reduced the recurrence rate of 6.5% to 8.3%, developed new warts in compared 8.8% in placebo group.

Furthermore, application of Sinecatechins ointment with a 10% and 15% green tea extract showed a well tolerated mild or moderate adverse effect in all patients.

Truly, there is no doubt that green tea process a potential value for treatment of external genital warts (EGWs) through the efficacy of phytochemical catechin in induced apoptosis of microbacterial expression.


Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight

How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca


Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.

Sources
(1) Green tea extract for external anogenital warts.[No authors listed](PubMed)
(2) Sinecatechins 10% ointment: a green tea extract for the treatment of external genital warts by Gupta AK1, Daigle D2.(PubMed)
(3) Sinecatechins, a defined green tea extract, in the treatment of external anogenital warts: a randomized controlled trial by Tatti S1, Swinehart JM, Thielert C, Tawfik H, Mescheder A, Beutner KR(PubMed).

Phytochemical Alliin Reduced Metabolic Risk Factors Against Heart Disease, Stroke, and Diabetes in Vivo

Metabolic risk factors are the cluster conditions are associated with an increased risk of heart disease, stroke, and diabetes.

In other words, if you have 3 or more risk factors of too much fat around the waist, elevated blood pressure, high triglycerides, elevated blood sugar, and low HDL cholesterol, you are considered at a higher risk of cardiovascular disease and diabetes compared to those who have less.

There is no single cause of metabolic syndrome. However, most cases of MetS are found in overweight and obese patients, particularly in those with insulin resistance, the condition caused by the inability of the body to use insulin properly in converting sugar to energy.

Symptoms are depending on the risk factors which the patients have, such as high blood pressure and cholesterol and glucose.

Other than the aforementioned risk factors, epidemiologically, aging, family history, physical inactivity and women with polycystic ovary syndrome are at a higher risk of the condition onset.

Some researchers suggested the rise of metabolic syndrome in the US over the past few decades may be correlated with the promotion of a high-fat diet in the Western world.


Dr. Wabitsch, M., the lead scientist wrote, "Specific alterations of the Western Diet uniquely drive this process and are unrelated to calories. These alterations include too little fiber, omega-3 fatty acids, and micronutrients, and too many omega-6 fatty acids, trans-fats, branched-chain amino acids, ethanol, and fructose. The food industry invokes personal responsibility while denying any corporate responsibility and citing scientific, policy, and social arguments. However, their responses obfuscate the scientific truth in order to obviate their culpability".


Alliin (S-allyl-L-cysteine-S-oxide) is a phytochemical compound sulfoxide,. a derivative of the amino acid cysteine, belonging to the class of sulfur compounds, found abundantly in fresh garlic and onion.

On finding a natural compound for the treatment of metabolic risk in diabetics, researchers investigated the effects of alliin (S-allyl cysteine sulfoxide) is a bioactive sulfoxide compound derived from garlic against metabolic risk factors in a diet-induced animal model.

The selected diet-induced obese C57BL/6J DIO mice were treated by drinking water with or without alliin (0.1 mg/ml) for 8 weeks.

According to the tested assays, alliin showed no significant effect on the body weight, adiposity or energy balance, however, alliin significantly reduced the levels of glucose homeostasis, increased insulin sensitivity and the lipid profile associated with metabolic risk factors.


The efficacy of alliin against the onset of hyperglycemia in obese tested mice was attributed at least in part by balancing the levels of gut microbiota.

In other words, alliin modulated of the intestinal microbiota composition by decreasing levels of Lachnospiraceae and increasing levels of Ruminococcaceae.

Based on the findings, researchers said, "alliin has nutraceutical or even medicinal potential in the prevention of diabetes and lipid metabolic disorders(in the induction of hyperglycemia and hyperlipidemia)".

Furthermore, in order to reveal more information about alliin antimetabolic activity, researchers compared the therapeutic effects of alliin extracted from garlic leaves of plants grown under ex-situ and in situ conditions.


According to the results of bioanalysis on normal and alloxan-induced diabetic rats in five weeks experiment
* Alliin produced from in situ grown-plants showed a significant reduction of the serum glucose, triglycerides, total lipids, total cholesterol, low-density lipoprotein (LDL)-, and very low-density lipoprotein (VLDL)-cholesterol in diabetic rats of 54%, 15%, 14%, 20%, 24%,and 15% repetitively.

* Alliin produced from ex-situ grown-plants showed lesser effect in the reduction of 35%, 14%, 10%, 12%, 17%, and 11%, respectively

* Both were compared to those treated with distilled water.

* Additionally, alliin produced from in and ex-situ grown-plants showed no effect on high-density lipoprotein (HDL)-cholesterol.

Based on the findings, Dr. Nasim SA, the lead scientist wrote, "These findings demonstrate leaf extract obtained from plants grown under in situ conditions possess higher therapeutic efficiency in comparison with leaf extract obtained from plants grown under ex situ condition".

In other words, alliin produced from original grown-plants is more effective compared to alliin produced by ex-situ.

Taken altogether, alliin may be considered supplements for reducing metabolic risk with no side effect, responding to the confirmation of the larger sample size and multicenter human study.

Intake of alliin in the form of supplement should be taken with extreme care to prevent overdose acute liver toxicity.

Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight

How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca


Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.

Sources
(1) Hypoglycemic and hypolipidemic effect of S-allyl-cysteine sulfoxide (alliin) in DIO mice.
Zhai B1, Zhang C1, Sheng Y1, Zhao C2, He X1,3, Xu W1,3, Huang K1,3, Luo Y. (PubMed)
(2) Alliin obtained from leaf extract of garlic grown under in situ conditions possess higher therapeutic potency as analyzed in alloxan-induced diabetic rats by Nasim SA1, Dhir B, Kapoor R, Fatima S, Mahmooduzzafar, Mujib A. (PubMed)
(3) Metabolic Syndrome and Obesity in Childhood and Adolescence by Editor(s): Kiess, W. (Leipzig), Wabitsch, M. (Ulm), Maffeis, C. (Verona), and Sharma, A.M. (Edmonton, Alta.). (Karger)

Friday, June 28, 2019

Green tea, the Best Anti Obesity Functional Food

Obesity is a medical condition of excess body fat accumulated overtime. A person is considered an obese if excess body weight relatively to the height is over 30 in BMI index.

According to the University of the Punjab, Epigallocatechin gallate, a polyphenol found in tea plants exhibited anti obesity effect through modulation of thePPAR[gamma] pathway in metabolism involved fat cells/adipose tissues.

In animal study, the chemical constituent stopped the adipogenic cell differentiation through different proteins and transcription factors in expression of adipocyte formation which is considered as fat cell development in contribution to obesity.

Dr. Javaid MS, the lead author in the study said, "Docking analysis of PPAR gamma and epigallocatechin gallate demonstrated that epigallocatechin gallate binds with PPAR gamma at its active site and blocks its activity".

Also, in animal induced by high fat diet, green tea Epigallocatechin 3-gallate (EGCG),exerted anti obesity effects through reduced plasma glucose and alleviate complications of diabetes by attenuating advanced glycation end products (AGEs) formation involved proteins or lipids expression.

Dietary EGCG tested in C57BL/6 mice induced by high-fat diet with or without ECGC for 17 weeks and compared to a control group placed on low-fat diet for the same period, also showed a significanty reduced weight gain, plasma glucose, insulin level, liver and kidney weight, which can be seen in obesity in compared control mice.

Importantly, green tea Epigallocatechin 3-gallate (EGCG fed mice novally decreased the levels of AGEs(advanced glycation end product) in both plasma and liver while inhibiting the receptor for AGE (RAGE) expression of activating Nrf2, antioxidant response and enhanced anti oxidative stress ratio of GSH/GSSG.


Other searchers opinionated the effect of green tea in reduced fat/adipose tissues accumulation in obese subject is a result of the pro-oxidant action of EGCG, in de activated cellular production of reactive oxygen species, through indication of adenosine monophosphate-activated protein kinase in suppressed gene and protein expression of enzymes and transcription factors involved in adipogenesis and lipogenesis(fat and adiposed metabolism).

Taking together, green tea with all the phytochemicals may be used as anti obesity functional food to help control hyperglycemia, reduce weight, and alleviate diabetes complications.


Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight

How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca


Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.

Sources
(1) Epigallocatechin Gallate as an anti-obesity therapeutic compound: an in silico approach for structure-based drug designing by Javaid MS1, Latief N1, Ijaz B1, Ashfaq UA2(PubMed).
(2) Green tea epigallocatechin 3-gallate alleviates hyperglycemia and reduces advanced glycation end products via nrf2 pathway in mice with high fat diet-induced obesity by Sampath C1, Rashid MR1, Sang S2, Ahmedna M3(PubMed)
(3) Beneficial Effects of Tea and the Green Tea Catechin Epigallocatechin-3-gallate on Obesity by Suzuki T1, Pervin M2, Goto S3, Isemura M4, Nakamura Y5.(PubMed)

Whole Food Tomato Protects the Obese Against Obesity-Related Co-Morbidities

Obesity is a disease characterized by excess body fat has accumulated over time. A BMI of over 30 is an indication of obesity.

Overweight is a condition of excess body weight relative to height, a BMI that is between 25 to 29.9 is considered overweight.

According to the statistics, 68% of the American population is either overweight or obese. Obesity has been found to induce adverse effects nearly every system of the human body, leading to increased risk of numerous diseases, including diabetes and cardiovascular disease.

Furthermore, the rate of obesity continues to climb at an alarming rate, that leads to significant burdens to the country economy and health care system.

Currently, there is not an effective treatment of the disease. However, some researchers suggested that combat the powerful environmental factors that influence eating and physical activity, particularly in the economy that may be the best approach to reduce the risk of obesity.


Bariatric surgery has been proposed to patients with extreme obesity (BMI of 40 or higher) due to weight-induced a serious weight-related health problem, such as diabetes or high blood pressure accompanied by the commitment of lifestyle changes. However, this type of surgery has posted a serious risk of many patients if the commitment of making lifelong changes in the eating and exercise habits cannot be followed through.


There are many risk factors associated with the onset of obesity. Some researchers suggested that the widespread obesity in the US may be correlated to the promotion high-fat diet over the past few decades.

Dr, Golay A, the lead scientist at the Geneva University Hospital, wrote, "Epidemiological evidence suggests that a high-fat diet promotes the development of obesity and that there is a direct relationship between the amount of dietary fat and the degree of obesity".

And, "Dietary fat induces overconsumption and weight gain through its low satiety properties and high caloric density. Obese and post-obese subjects do not appear to adapt to dietary fat, and therefore fat storage is increased".

Tomato is red, edible fruit, genus Solanum, belongs to family Solanaceae, native to South America. Because of its health benefits, the tomato is grown worldwide for the commercial purpose
and often in the greenhouse.

On finding a natural and potential compound for the treatment of obesity complication, researchers investigated the effect of the potent tomato-derived antioxidant and oxidative status, and inflammatory markers in obese.

The study included the comparison of 8 obese patients (body mass index 37.5 +/- 2.5 kg/m2) with a control group of eight lean, age and gender-matched subjects (BMI 21.6 +/- 0.6 kg/m2), before and after 4 weeks of lycopene supplementation (tomato-derived Lyc-O-Mato) (30 mg daily).

Before treatment, according to the tested results, compared to control, obese subjects showed significantly reduced levels of plasma carotenoids, increased levels of CRP and expression of pro-inflammatory cytokine and oxidative stress.

Additional analysis of the findings, BMI was correlated with increased expression of CRP, proinflammation (IL-6) and oxidative stress.
The presence of high levels IL-6 and oxidative stress also found to correlate inversely with carotenoids (P < 0.05).

In other words, obese induced increased levels of CRP, IL-6, and oxidative stress were attributed probably by the depletion of antioxidant enzymes produced by the host.

After treatment, lycopene a significant elevation of plasma carotenoids (1.79 vs. 0.54 microg/ml) and plasma of lycopene (1.15 vs 0.23 microg/ml) in the subjects compared to the placebo group.

The results suggested that injection of lycopene improved the levels of antioxidants enzymes in the obese, thus preventing the occurrence of diseases associated with CRP, IL-6, and oxidative stress without affecting the markers of inflammation and oxidation products.

Based on the results, researchers concluded, "Obese patients showed abnormally higher markers of inflammation and oxidation products and lower plasma carotenoids".

And, "The lack of reduction of pro-inflammatory markers could be attributed to the short period of the study and the small number of participants".

Taken altogether, tomatoes processed a high amount of lycopene may be considered supplements for the prevention of obesity-related co-morbidities, pending to the confirmation of the larger sample size and multicenter human study.

Intake of lycopene in the form of supplement should be taken with extreme care to prevent overdose acute liver toxicity.

Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight

How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca


Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.

Sources
(1) The effect of tomato-derived lycopene on low carotenoids and enhanced systemic inflammation and oxidation in severe obesity by Markovits N1, Ben Amotz A, Levy Y. (PubMed)
(2) The role of dietary fat in obesity by Golay A1, Bobbioni E. (PubMed)