Cardiovascular disease (CVD) is a class of diseases associated with the blood vessels. Depending on the types of blood vessel damage or blocked, CVD can be a coronary artery disease caused by the hardening of the arteries that interfere with the blood flow to the heart.
Heart failure, a major health problem associated with the reduced function of the heart that affects more than 6.5 million Americans is also a leading cause of hospitalization in people older than age 65.
According to the statistics provided by the CDC, every year, heart disease causes the death of 610,000 people in the United States. In other words, every year, 1 in every 4 deaths in the US are caused by heart disease.
Believe it or not, every year about 735,000 Americans have a heart attack including the first attack of 525,000 patients.
Epidemiologically, risk factors associated with cardiovascular disease include family history, age ethnicity, gender, medical conditions such as cholesterol high blood pressure and diabetes.
Out of many risk factors, some researchers suggested the widespread obesity caused by the promotion of a high-fat diet over the past few decades may be one major condition that causes the onset of CVD.
Dr. Frank M. Sacks wrote, " Prospective observational studies in many populations showed that lower intake of saturated fat coupled with higher intake of polyunsaturated and monounsaturated fat is associated with lower rates of CVD and of other major causes of death and all-cause mortality. In contrast, replacement of saturated fat with mostly refined carbohydrates and sugars is not associated with lower rates of CVD and did not reduce CVD in clinical trials".
And, "Replacement of saturated with unsaturated fats lowers low-density lipoprotein cholesterol, a cause of atherosclerosis, linking biological evidence with the incidence of CVD in populations and in clinical trials".
Tomato is red, edible fruit, genus Solanum, belongs to family Solanaceae, native to South America. Because of its health benefits, the tomato is grown worldwide for the commercial purpose
and often in the greenhouse.
With an aim to find a natural treatment of cardiovascular disease, researchers evaluated the state of the evidence from intervention trials on the effect of consuming tomato products and lycopene on markers of cardiovascular (CV) function.
By searching the medical literature database of Medline, Web of science, and Scopus from inception to August 2016, 21 studies fulfilled inclusion criteria out of 1189 publications were identified.
According to the results from the meta-analyses, overall, interventions supplementing tomato were associated with significant reductions in LDL-cholesterol, inflammatory cytokine IL-6.
Furthermore, tomato injection improved the arteries function in blood circulation (flow-mediated dilation (FMD).
Compared to tomatoes, lycopene supplementation only reduced systolic-BP.
In other words, with the exception of blood pressure management by lycopene supplementation, dietary tomato provided more favorable results on cardiovascular risk, compared to lycopene supplementation.
The results strongly support the use of dietary tomatoes for the prevention of CVD.
Dr. Cheng HM. after taking other factors into accounts said, "The available evidence on the effects of tomato products and lycopene supplementation on CV risk factors supports the view that increasing the intake of these has positive effects on blood lipids, blood pressure, and endothelial function".
Taken altogether, tomatoes may be considered supplements for the prevention and treatment of CVD, pending to the confirmation of the larger sample size and multicenter human study.
Intake of lycopene in the form of supplement should be taken with extreme care to prevent overdose acute liver toxicity.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Tomato and lycopene supplementation and cardiovascular risk factors: A systematic review and meta-analysis by Cheng HM1, Koutsidis G1, Lodge JK1, Ashor A2, Siervo M2, Lara J. (PubMed)
(2) Whole food versus supplement: comparing the clinical evidence of tomato intake and lycopene supplementation on cardiovascular risk factors by Burton-Freeman B, Sesso HD. (PubMed)
(3) Dietary Fats and Cardiovascular Disease: A Presidential Advisory From the American Heart AssociationFrank M. Sacks, Alice H. Lichtenstein, Jason H.Y. Wu, Lawrence J. Appel, Mark A. Creager, Penny M. Kris-Etherton, Michael Miller, Eric B. Rimm, Lawrence L. Rudel, Jennifer G. Robinson. (Circulation)
Tuesday, July 9, 2019
Monday, July 8, 2019
Green tea, the Best Immunomodulated Functional Foods
Green tea is found to consist of a strong immunomodulating effect, affecting the innate and adaptive immune systems, a renowned institute study suggested
Green tea, a precious drink processes numbers of health benefit known to almost everyone in Asia and the Western world. However, as yin in nature herbal medicine or food, long term injection of large amounts may obstruct the balance of yin-yang, induced "yin excessive syndrome" or "yang vacuity syndrome" including weaken immunity and painful case of GERD,... according to traditional Chinese medicine's Yin-Yang theory.
According to the Harvard Medical School, epigallocatechin-3-gallate (EGCG) isolated from green tea expressed a strong effect on T cell functions, including T cell activation, proliferation, differentiation, and production of cytokines.
Injection of the phytochemical in the animal model showed significant effects in regulated T cell dysfunction in the expression of autoimmune inflammatory diseases as well as ameliorated T cell-mediated autoimmune diseases.
Furthermore, in naïve CD4(+) T cells proliferate and differentiate into different effector subsets, green tea EGCG inhibited the pro-inflammatory Th1 and Th17 cells, subsets of Th cells responsible for inducing autoimmunity, thus improving symptoms and reducing the pathology of autoimmune diseases.
Additionally, Dr. Wu D, the lead author said, "(The) protective effect EGCG is associated with the suppressed proliferation of autoreactive T cells, in reduced production of pro-inflammatory cytokines of Th1 and Th17, and increased T cell regulation populations in lymphoid tissues and central nervous system".
Further evaluation of green tea EGCG effect in regulated CD4(+) T helper (Th) subsets Th1, Th9, and Th17 cells conducted by the Tufts University, postulated that the phytochemical impeded Th1, Th9, and Th17 differentiation in exhibited inflammation by prevented IL-6(the pro-inflammatory cytokine)-induced suppression of Treg development.
More importantly, in experimental autoimmune encephalomyelitis (EAE) rats, EGCG improved function of CD4(+) T cell through modulated the expression of IL-6 induced cytokine(gp130) in response to autoimmune function and cellular response.
Taking together, green tea process a strong immunomodulating effect in reduced risk and treatment of autoinflammatory and immune disease, but long term and large amount intake should be taken with care to prevent toxicity.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Immunomodulating effects of epigallocatechin-3-gallate from green tea: mechanisms and applications by Pae M1, Wu D.(PubMed)
(2) Green tea EGCG, T cells, and T cell-mediated autoimmune diseases by Wu D1, Wang J, Pae M, Meydani SN.(PubMed)
(3) Green tea epigallocatechin-3-gallate modulates differentiation of naïve CD4⁺ T cells into specific lineage effector cells by Wang J1, Pae M, Meydani SN, Wu D.(PubMed)
Green tea, a precious drink processes numbers of health benefit known to almost everyone in Asia and the Western world. However, as yin in nature herbal medicine or food, long term injection of large amounts may obstruct the balance of yin-yang, induced "yin excessive syndrome" or "yang vacuity syndrome" including weaken immunity and painful case of GERD,... according to traditional Chinese medicine's Yin-Yang theory.
According to the Harvard Medical School, epigallocatechin-3-gallate (EGCG) isolated from green tea expressed a strong effect on T cell functions, including T cell activation, proliferation, differentiation, and production of cytokines.
Injection of the phytochemical in the animal model showed significant effects in regulated T cell dysfunction in the expression of autoimmune inflammatory diseases as well as ameliorated T cell-mediated autoimmune diseases.
Furthermore, in naïve CD4(+) T cells proliferate and differentiate into different effector subsets, green tea EGCG inhibited the pro-inflammatory Th1 and Th17 cells, subsets of Th cells responsible for inducing autoimmunity, thus improving symptoms and reducing the pathology of autoimmune diseases.
Additionally, Dr. Wu D, the lead author said, "(The) protective effect EGCG is associated with the suppressed proliferation of autoreactive T cells, in reduced production of pro-inflammatory cytokines of Th1 and Th17, and increased T cell regulation populations in lymphoid tissues and central nervous system".
Further evaluation of green tea EGCG effect in regulated CD4(+) T helper (Th) subsets Th1, Th9, and Th17 cells conducted by the Tufts University, postulated that the phytochemical impeded Th1, Th9, and Th17 differentiation in exhibited inflammation by prevented IL-6(the pro-inflammatory cytokine)-induced suppression of Treg development.
More importantly, in experimental autoimmune encephalomyelitis (EAE) rats, EGCG improved function of CD4(+) T cell through modulated the expression of IL-6 induced cytokine(gp130) in response to autoimmune function and cellular response.
Taking together, green tea process a strong immunomodulating effect in reduced risk and treatment of autoinflammatory and immune disease, but long term and large amount intake should be taken with care to prevent toxicity.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Immunomodulating effects of epigallocatechin-3-gallate from green tea: mechanisms and applications by Pae M1, Wu D.(PubMed)
(2) Green tea EGCG, T cells, and T cell-mediated autoimmune diseases by Wu D1, Wang J, Pae M, Meydani SN.(PubMed)
(3) Green tea epigallocatechin-3-gallate modulates differentiation of naïve CD4⁺ T cells into specific lineage effector cells by Wang J1, Pae M, Meydani SN, Wu D.(PubMed)
Bromelain Protects the Rotator Cuff Against the Onset of Tendinitis
Tendinitis is inflammation or irritation of a tendon as a result of overuse, infection or rheumatic disease.
In other words, people who have an occupation or sport that requires a repetition of particular movement putting stress on the tendons over time are associated with the risk of tendinitis, including the tennis elbow, golfer's elbow, swimmer's shoulder, and jumper's knee.
Most common symptoms of tendinitis are a dull pain that affects limb or joint, tenderness and mild swelling.
Most common prevalent factors of tendinitis are aging, sport, occupation.
According to the Bureau of Labor Statistics, in the US, tendonitis (swelling of the tendons) is a fairly common problem, accounting for more than 70,000 people to miss work per year.
Tendinitis if untreated may induce complication of tendon rupture, a serious condition that may require surgery.
Long-term or persistently of tendon irritation has been found to induce tendinosis that leads to the degenerative changes in the tendon.
Conventionally, the immediate treatment for tendonitis caused by occupation is rest, ice, compression, and elevation of the injured tendon. pain relievers and anti-inflammatory drugs are prescribed to ease inflammation and pain.
Bromelain, a proteolytic enzyme found in pineapples (Ananas comosus) has been used in traditional medicine as an inflammatory agent and to treat pains, strains, and muscle aches and pains and ease back pain and chronic joint pain, skin diseases, etc.
On finding a natural compound for the treatment of tendinitis, researchers examined the effect of bromelain on patients with rotator cuff tendinitis.
Tenosan * (arginine L-alpha-ketoglutarate, methylsulfonylmethane, hydrolyzed type I collagen and bromelain), a commercial supplement sold in Italy was used in the study to test for its activity in tendon healing and mitigating the pain due to tendonitis.
Participants in the study included 90 consecutive patients with a large, postero-superior rotator cuff tear (RCT). managed with an arthroscopic repair randomly assigned into either Group I with or Group II without the supplement.
Supplement treated group showed a significant effect on the shoulder pain (follow-up: 6 months) and repair integrity on the final follow-up.
In other words, supplement after 3 months and after cuff repair decreases shoulder post-operative pain and a slight improvement in repair integrity.
Additional observation of the results, researchers suggested that these improvements may have a strong impact on the postoperative rehabilitation program and reduced the re-rupture rate.
Taken altogether, bromelain used alone or combined with other herbal remedies may be considered supplements for the treatment of rotator cuff tendinitis, pending to the confirmation of the larger sample size and multicenter human study.
Intake of bromelain in the form of supplement should be taken with extreme care to prevent overdose acute liver toxicity.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Arginine L-alpha-ketoglutarate, methylsulfonylmethane, hydrolyzed type I collagen and bromelain in rotator cuff tear repair: a prospective randomized study by Gumina S1, Passaretti D, Gurzì MD, Candela V. (PubMed)
(2) Naturopathic treatment of rotator cuff tendinitis among Canadian postal workers: a randomized controlled trial by Szczurko O1, Cooley K, Mills EJ, Zhou Q, Perri D, Seely D. (PubMed)
In other words, people who have an occupation or sport that requires a repetition of particular movement putting stress on the tendons over time are associated with the risk of tendinitis, including the tennis elbow, golfer's elbow, swimmer's shoulder, and jumper's knee.
Most common symptoms of tendinitis are a dull pain that affects limb or joint, tenderness and mild swelling.
Most common prevalent factors of tendinitis are aging, sport, occupation.
According to the Bureau of Labor Statistics, in the US, tendonitis (swelling of the tendons) is a fairly common problem, accounting for more than 70,000 people to miss work per year.
Tendinitis if untreated may induce complication of tendon rupture, a serious condition that may require surgery.
Long-term or persistently of tendon irritation has been found to induce tendinosis that leads to the degenerative changes in the tendon.
Conventionally, the immediate treatment for tendonitis caused by occupation is rest, ice, compression, and elevation of the injured tendon. pain relievers and anti-inflammatory drugs are prescribed to ease inflammation and pain.
Bromelain, a proteolytic enzyme found in pineapples (Ananas comosus) has been used in traditional medicine as an inflammatory agent and to treat pains, strains, and muscle aches and pains and ease back pain and chronic joint pain, skin diseases, etc.
On finding a natural compound for the treatment of tendinitis, researchers examined the effect of bromelain on patients with rotator cuff tendinitis.
Tenosan * (arginine L-alpha-ketoglutarate, methylsulfonylmethane, hydrolyzed type I collagen and bromelain), a commercial supplement sold in Italy was used in the study to test for its activity in tendon healing and mitigating the pain due to tendonitis.
Participants in the study included 90 consecutive patients with a large, postero-superior rotator cuff tear (RCT). managed with an arthroscopic repair randomly assigned into either Group I with or Group II without the supplement.
Supplement treated group showed a significant effect on the shoulder pain (follow-up: 6 months) and repair integrity on the final follow-up.
In other words, supplement after 3 months and after cuff repair decreases shoulder post-operative pain and a slight improvement in repair integrity.
Additional observation of the results, researchers suggested that these improvements may have a strong impact on the postoperative rehabilitation program and reduced the re-rupture rate.
Taken altogether, bromelain used alone or combined with other herbal remedies may be considered supplements for the treatment of rotator cuff tendinitis, pending to the confirmation of the larger sample size and multicenter human study.
Intake of bromelain in the form of supplement should be taken with extreme care to prevent overdose acute liver toxicity.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Arginine L-alpha-ketoglutarate, methylsulfonylmethane, hydrolyzed type I collagen and bromelain in rotator cuff tear repair: a prospective randomized study by Gumina S1, Passaretti D, Gurzì MD, Candela V. (PubMed)
(2) Naturopathic treatment of rotator cuff tendinitis among Canadian postal workers: a randomized controlled trial by Szczurko O1, Cooley K, Mills EJ, Zhou Q, Perri D, Seely D. (PubMed)
Sunday, July 7, 2019
Green Tea, the Best Functional in Reduced Risk and Treatment of chronic obstructive pulmonary disease (COPD)
Green tea may be considered as a potential pharmacotherapy for asthma and chronic obstructive pulmonary disease (COPD), a renowned institute study suggested.
Green tea, a precious drink processes numbers of health benefit known to almost everyone in Asia and the Western world. However, as yin in nature herbal medicine, or food, long term injection of large amounts may obstruct the balance of yin-yang, induced "yin excessive syndrome" or "yang vacuity syndrome" including weaken immunity and painful case of GERD,... according to traditional Chinese medicine's Yin-Yang theory. Adding a slice of ginger will resolve the problem.
Chronic obstructive pulmonary disease (COPD) is a condition of lung disease caused by obstruction of airflow in normal breathing.
In a total of 13,651 adults from three Dutch cities examined from 1994 to 1997. observation of dietary intake estimated using a food frequency questionnaire, and flavonoid intake calculated using specific food composition tables, showed a significant effect of flavonoid intake regularly in reduced risk COPD.
According to the returned questionnaire, total catechin, flavonol, and flavone intake was positively associated with FEV1 in the air flow of a deep breath and inversely associated with chronic cough and breathlessness, common symptoms of chronic obstructive pulmonary disease (COPD).
More specified, Dr. Tabak C, the lead author said, "Flavonol and flavone intake was independently associated with a chronic cough only"
Furthermore, Chafuroside A (CFA), a water-soluble flavone C-glycoside, isolated from oolong tea, in oral administration exhibited at 0.5mg/kg or higher exhibited a profound effect in attenuated inflammatory symptoms in a dose-dependent manner, in experimental asthma/chronic obstructive pulmonary disease (COPD)-like model.
In fact, Biomarker profiling revealed that the CFA/SAM at 0.1mg CFA/kg equipotent to CFA at 1.0mg/kg testing result also expressed protective activity against antigen-induced airway inflammation.
Taking together, there is no doubt that green tea may be used as therapeutic and functional food for reduced risk and treatment of chronic obstructive pulmonary disease (COPD) through the expression of plant phytochemicals, but large amount intake regularly should be taken with care in prevented toxicity.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Phytoceuticals: the new 'physic garden' for asthma and chronic obstructive pulmonary disease by Grandhi S1, Donnelly LE, Rogers DF.(PubMed)
(2) Chronic obstructive pulmonary disease and intake of catechins, flavonols, and flavones: the MORGEN Study by Tabak C1, Arts IC, Smit HA, Heederik D, Kromhout D.(PubMed)
(3) Self-assembled micellar formulation of chafuroside A with improved anti-inflammatory effects in experimental asthma/COPD-model rats by Onoue S1, Matsui T, Aoki Y, Ishida H, Nukaya H, Kou K, Yamada S.(PubMed)
Green tea, a precious drink processes numbers of health benefit known to almost everyone in Asia and the Western world. However, as yin in nature herbal medicine, or food, long term injection of large amounts may obstruct the balance of yin-yang, induced "yin excessive syndrome" or "yang vacuity syndrome" including weaken immunity and painful case of GERD,... according to traditional Chinese medicine's Yin-Yang theory. Adding a slice of ginger will resolve the problem.
Chronic obstructive pulmonary disease (COPD) is a condition of lung disease caused by obstruction of airflow in normal breathing.
In a total of 13,651 adults from three Dutch cities examined from 1994 to 1997. observation of dietary intake estimated using a food frequency questionnaire, and flavonoid intake calculated using specific food composition tables, showed a significant effect of flavonoid intake regularly in reduced risk COPD.
According to the returned questionnaire, total catechin, flavonol, and flavone intake was positively associated with FEV1 in the air flow of a deep breath and inversely associated with chronic cough and breathlessness, common symptoms of chronic obstructive pulmonary disease (COPD).
More specified, Dr. Tabak C, the lead author said, "Flavonol and flavone intake was independently associated with a chronic cough only"
Furthermore, Chafuroside A (CFA), a water-soluble flavone C-glycoside, isolated from oolong tea, in oral administration exhibited at 0.5mg/kg or higher exhibited a profound effect in attenuated inflammatory symptoms in a dose-dependent manner, in experimental asthma/chronic obstructive pulmonary disease (COPD)-like model.
In fact, Biomarker profiling revealed that the CFA/SAM at 0.1mg CFA/kg equipotent to CFA at 1.0mg/kg testing result also expressed protective activity against antigen-induced airway inflammation.
Taking together, there is no doubt that green tea may be used as therapeutic and functional food for reduced risk and treatment of chronic obstructive pulmonary disease (COPD) through the expression of plant phytochemicals, but large amount intake regularly should be taken with care in prevented toxicity.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Phytoceuticals: the new 'physic garden' for asthma and chronic obstructive pulmonary disease by Grandhi S1, Donnelly LE, Rogers DF.(PubMed)
(2) Chronic obstructive pulmonary disease and intake of catechins, flavonols, and flavones: the MORGEN Study by Tabak C1, Arts IC, Smit HA, Heederik D, Kromhout D.(PubMed)
(3) Self-assembled micellar formulation of chafuroside A with improved anti-inflammatory effects in experimental asthma/COPD-model rats by Onoue S1, Matsui T, Aoki Y, Ishida H, Nukaya H, Kou K, Yamada S.(PubMed)
Antioxidants Carotenoids Protect the Colonic Cells Integrity Against Colon Cancer
The colon or large intestine formed part of the digestive system plays a critical role to remove waste products from your body.
In other words, the colon works alongside with other digestive organs to remove stool and maintain your fluid and electrolyte balance.
The colon begins at the end of the small intestine and ends at the rectum.
More precisely, the large intestine can be broken into six sections including the cecum, ascending colon, transverse colon, descending colon, sigmoid colon, and the rectum.
Colon cancer is a medical condition caused by irregular cell growth in the cells on the surface of the inner lining of the colon tissues. At the early stage, most patients are assymptomatic.
Colon cancer can be classified depending on the location and cells origination
* Adenocarcinomas
Most cases of colon cancer are adenocarcinomas, originated in epithelium tissues, including the surface layer of skin, glands and their tissues that line the cavities and organs of the body.
* Squamous cell cancers
Squamous cells are the skin like cells that make up the colon lining together with the gland cells. Squamous cell cancers are rare with the risk of 25 per 100000.
Other colon tumors
* Carcinoid
Carcinoid is an unusual type of slow growth neuroendocrine tumor. It looks benign but might spread to other parts of the body as they grow in hormone-producing tissue in the digestive system.
* Leiomyosarcomas
Leiomyosarcomas are the rare and resistant types of colon cancer and generally not very responsive to chemotherapy or radiation. They are a malignant abnormal mass of tissue of smooth muscles of the colon, comprising between 5–10% of soft tissue sarcomas.
* Melanomas
Melanomas are a rare malignant tumor of cells that produce the dark pigment. This type of colon cancer usually originates from somewhere else before spreading to the colon.
According to the statistic provided by the American Cancer Society, in 2019, approximately, 101,420 new cases of colon cancer will be diagnosed in the US. The risk of colon cancer is slightly lower in women than in men.
Bowel cancer also known as colorectal cancer, is defined as a condition of the abnormal proliferation of cells in the colon, rectum, or vermiform appendix.
Carotenoids is a class of mainly yellow, orange, or red fat-soluble pigments, including lycopene and carotene, found abundantly in ripe tomato, pumpkins, carrots, corn, and daffodils.
On finding a potential compound for the treatment of colon cancer, researchers investigated the antiproliferative activity of carotenoids separated from marine Chlorella ellipsoidea and freshwater Chlorella vulgaris on colon cancer cell line.
Based on the chemical analysis, the carotenoid from C. vulgaris was almost completely composed of lutein compared to carotenoid from C. ellipsoidea that was composed of violaxanthin with two minor xanthophylls, antheraxanthin, and zeaxanthin.
According to the tested assays, both semipurified extracts of C. ellipsoidea and C. vulgaris inhibited HCT116 cell growth in a dose-dependent manner, with the effective IC(50) values of 40.73 +/- 3.71 and 40.31 +/- 4.43 microg/mL, respectively.
In other words, both carotenoids even with different major chemical compound exerted a similar inhibitory activity in the tested cancer cell line.
Furthermore, both extracts also demonstrated a significant effect on inducing cancer cell apoptosis. However, C. ellipsoidea extract produced an apoptosis-inducing effect almost 2.5 times stronger than that of the C. vulgaris extract.
The results strongly suggested that there must be other unknown compounds found in C. ellipsoidea extract but not in C. vulgaris that causes the additional death of the cancer cell population.
Dr. Cha KH, the lead scientist after taking other factors into account wrote, "These results indicate that bioactive xanthophylls of C. ellipsoidea might be useful functional ingredients in the prevention of human cancers".
Taken altogether, carotenoids may be considered a remedy for the prevention and treatment of colon cancer, pending to the confirmation of the larger sample size and multicenter human study.
Intake of carotenoids in the form of supplement should be taken with extreme care to prevent overdose acute liver toxicity.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Plasma and dietary carotenoids and vitamins A, C and E and risk of colon and rectal cancer in the European Prospective Investigation into Cancer and Nutrition by Leenders M1, Leufkens AM, Siersema PD, van Duijnhoven FJ, Vrieling A, Hulshof PJ, van Gils CH, Overvad K, Roswall N, Kyrø C, Boutron-Ruault MC, Fagerhazzi G, Cadeau C, Kühn T, Johnson T, Boeing H, Aleksandrova K, Trichopoulou A, Klinaki E, Androulidaki A, Palli D, Grioni S, Sacerdote C, Tumino R, Panico S, Bakker MF, Skeie G, Weiderpass E, Jakszyn P, Barricarte A, María Huerta J, Molina-Montes E, Argüelles M, Johansson I, Ljuslinder I, Key TJ, Bradbury KE, Khaw KT, Wareham NJ, Ferrari P, Duarte-Salles T, Jenab M, Gunter MJ, Vergnaud AC, Wark PA, Bueno-de-Mesquita HB. (PubMed)
(2) Antiproliferative effects of carotenoids extracted from Chlorella ellipsoidea and Chlorella vulgaris on human colon cancer cells by Cha KH1, Koo SY, Lee DU. (PubMed)
(2) Bowel (Colorectal ) Cancer by Kyle J. Norton
In other words, the colon works alongside with other digestive organs to remove stool and maintain your fluid and electrolyte balance.
The colon begins at the end of the small intestine and ends at the rectum.
More precisely, the large intestine can be broken into six sections including the cecum, ascending colon, transverse colon, descending colon, sigmoid colon, and the rectum.
Colon cancer is a medical condition caused by irregular cell growth in the cells on the surface of the inner lining of the colon tissues. At the early stage, most patients are assymptomatic.
Colon cancer can be classified depending on the location and cells origination
* Adenocarcinomas
Most cases of colon cancer are adenocarcinomas, originated in epithelium tissues, including the surface layer of skin, glands and their tissues that line the cavities and organs of the body.
* Squamous cell cancers
Squamous cells are the skin like cells that make up the colon lining together with the gland cells. Squamous cell cancers are rare with the risk of 25 per 100000.
Other colon tumors
* Carcinoid
Carcinoid is an unusual type of slow growth neuroendocrine tumor. It looks benign but might spread to other parts of the body as they grow in hormone-producing tissue in the digestive system.
* Leiomyosarcomas
Leiomyosarcomas are the rare and resistant types of colon cancer and generally not very responsive to chemotherapy or radiation. They are a malignant abnormal mass of tissue of smooth muscles of the colon, comprising between 5–10% of soft tissue sarcomas.
* Melanomas
Melanomas are a rare malignant tumor of cells that produce the dark pigment. This type of colon cancer usually originates from somewhere else before spreading to the colon.
According to the statistic provided by the American Cancer Society, in 2019, approximately, 101,420 new cases of colon cancer will be diagnosed in the US. The risk of colon cancer is slightly lower in women than in men.
Bowel cancer also known as colorectal cancer, is defined as a condition of the abnormal proliferation of cells in the colon, rectum, or vermiform appendix.
Carotenoids is a class of mainly yellow, orange, or red fat-soluble pigments, including lycopene and carotene, found abundantly in ripe tomato, pumpkins, carrots, corn, and daffodils.
On finding a potential compound for the treatment of colon cancer, researchers investigated the antiproliferative activity of carotenoids separated from marine Chlorella ellipsoidea and freshwater Chlorella vulgaris on colon cancer cell line.
Based on the chemical analysis, the carotenoid from C. vulgaris was almost completely composed of lutein compared to carotenoid from C. ellipsoidea that was composed of violaxanthin with two minor xanthophylls, antheraxanthin, and zeaxanthin.
According to the tested assays, both semipurified extracts of C. ellipsoidea and C. vulgaris inhibited HCT116 cell growth in a dose-dependent manner, with the effective IC(50) values of 40.73 +/- 3.71 and 40.31 +/- 4.43 microg/mL, respectively.
In other words, both carotenoids even with different major chemical compound exerted a similar inhibitory activity in the tested cancer cell line.
Furthermore, both extracts also demonstrated a significant effect on inducing cancer cell apoptosis. However, C. ellipsoidea extract produced an apoptosis-inducing effect almost 2.5 times stronger than that of the C. vulgaris extract.
The results strongly suggested that there must be other unknown compounds found in C. ellipsoidea extract but not in C. vulgaris that causes the additional death of the cancer cell population.
Dr. Cha KH, the lead scientist after taking other factors into account wrote, "These results indicate that bioactive xanthophylls of C. ellipsoidea might be useful functional ingredients in the prevention of human cancers".
Taken altogether, carotenoids may be considered a remedy for the prevention and treatment of colon cancer, pending to the confirmation of the larger sample size and multicenter human study.
Intake of carotenoids in the form of supplement should be taken with extreme care to prevent overdose acute liver toxicity.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Plasma and dietary carotenoids and vitamins A, C and E and risk of colon and rectal cancer in the European Prospective Investigation into Cancer and Nutrition by Leenders M1, Leufkens AM, Siersema PD, van Duijnhoven FJ, Vrieling A, Hulshof PJ, van Gils CH, Overvad K, Roswall N, Kyrø C, Boutron-Ruault MC, Fagerhazzi G, Cadeau C, Kühn T, Johnson T, Boeing H, Aleksandrova K, Trichopoulou A, Klinaki E, Androulidaki A, Palli D, Grioni S, Sacerdote C, Tumino R, Panico S, Bakker MF, Skeie G, Weiderpass E, Jakszyn P, Barricarte A, María Huerta J, Molina-Montes E, Argüelles M, Johansson I, Ljuslinder I, Key TJ, Bradbury KE, Khaw KT, Wareham NJ, Ferrari P, Duarte-Salles T, Jenab M, Gunter MJ, Vergnaud AC, Wark PA, Bueno-de-Mesquita HB. (PubMed)
(2) Antiproliferative effects of carotenoids extracted from Chlorella ellipsoidea and Chlorella vulgaris on human colon cancer cells by Cha KH1, Koo SY, Lee DU. (PubMed)
(2) Bowel (Colorectal ) Cancer by Kyle J. Norton
Saturday, July 6, 2019
Green tea, The best Beverage for Lower Coronary Artery Disease Risk
A recent study conducted by a respectable institute suggested that green tea may have a potential effect on reduced risk and treatment of coronary artery disease.
Coronary artery disease is a condition of narrowing coronary arteries, caused by hardening arterial wall, cholesterol building up in the arteries, leading to blockage of the blood flow in the arteries.
Green tea, a precious drink processes numbers of health benefit known to almost everyone in Asia and the Western world. However, as yin in nature herbal medicine, or food, long term injection of large amounts may obstruct the balance of yin-yang, induced "yin excessive syndrome" or "yang vacuity syndrome" including weaken immunity and painful case of GERD,... according to traditional Chinese medicine's Yin-Yang theory. Adding a slice of ginger will do the trick of neutralization.
According to the review of literature of a study of 22 healthy volunteers, injection of green tea 7 cups/day exhibited anti cholesterol effects through modifying the low-density lipoprotein (MDA-LDL) concentrations and decreasing plasma C-reactive protein and interleukin (IL)-6 concentrations involving inflammatory expression.
Green tea consumption of less of 1 cup a day in 725 patients undergoing coronary angiography, is found to associate to lower risk of myocardial infarction (MI) in compared to CVD patients without MI and patients without CAD.
Dr. Ohmori R, the lead author said," Green tea consumption was found to be inversely associated with MI in Japanese patients" and " The protective effect of green tea against atherosclerosis is more likely to be because of the inhibitory effect of LDL oxidation than because of anti-inflammatory effect".
Additionally, the Japanese population with a green tea drinking habit, showed a significantly reduced risk of a decreased incidence of coronary artery disease (CAD), due to the presence of abundant polyphenolic antioxidants.
In a group of comprised 203 patients who underwent coronary angiography (109 patients with significant coronary stenosis and 94 patients without), coronary artery disease (CAD) is associated inversely in regular green tea drinking group.
The study showed that green tea intake per day was an independent predictor for CVD based on a multivariate logistic regression analysis. but not a predictor of cardiovascular diseases based on the Cox proportional hazard model.
Continuously, in researching the data of PUBMED and EMBASE for studies conducted from 1966 through November 2009 filed the following results:
1. 5 studies on green tea. indicated the lower relative risk is depended significantly between the highest green tea consumption and reduced risk of CVD.
2. The risk of CVD is reduced by 10% for every additional cup of green tea intake.
Taking together, green tea may be used as a functional food of healthy adults with a higher risk CVD.
However, long term and a large amount of green tea consumption should be taken with care to prevent toxicity.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Antioxidant beverages: green tea intake and coronary artery disease by Ohmori R1, Kondo K2, Momiyama Y3.(PubMed)
(2) Effects of green tea intake on the development of coronary artery disease by Sano J1, Inami S, Seimiya K, Ohba T, Sakai S, Takano T, Mizuno K.(PubMed)
Coronary artery disease is a condition of narrowing coronary arteries, caused by hardening arterial wall, cholesterol building up in the arteries, leading to blockage of the blood flow in the arteries.
Green tea, a precious drink processes numbers of health benefit known to almost everyone in Asia and the Western world. However, as yin in nature herbal medicine, or food, long term injection of large amounts may obstruct the balance of yin-yang, induced "yin excessive syndrome" or "yang vacuity syndrome" including weaken immunity and painful case of GERD,... according to traditional Chinese medicine's Yin-Yang theory. Adding a slice of ginger will do the trick of neutralization.
According to the review of literature of a study of 22 healthy volunteers, injection of green tea 7 cups/day exhibited anti cholesterol effects through modifying the low-density lipoprotein (MDA-LDL) concentrations and decreasing plasma C-reactive protein and interleukin (IL)-6 concentrations involving inflammatory expression.
Green tea consumption of less of 1 cup a day in 725 patients undergoing coronary angiography, is found to associate to lower risk of myocardial infarction (MI) in compared to CVD patients without MI and patients without CAD.
Dr. Ohmori R, the lead author said," Green tea consumption was found to be inversely associated with MI in Japanese patients" and " The protective effect of green tea against atherosclerosis is more likely to be because of the inhibitory effect of LDL oxidation than because of anti-inflammatory effect".
Additionally, the Japanese population with a green tea drinking habit, showed a significantly reduced risk of a decreased incidence of coronary artery disease (CAD), due to the presence of abundant polyphenolic antioxidants.
In a group of comprised 203 patients who underwent coronary angiography (109 patients with significant coronary stenosis and 94 patients without), coronary artery disease (CAD) is associated inversely in regular green tea drinking group.
The study showed that green tea intake per day was an independent predictor for CVD based on a multivariate logistic regression analysis. but not a predictor of cardiovascular diseases based on the Cox proportional hazard model.
Continuously, in researching the data of PUBMED and EMBASE for studies conducted from 1966 through November 2009 filed the following results:
1. 5 studies on green tea. indicated the lower relative risk is depended significantly between the highest green tea consumption and reduced risk of CVD.
2. The risk of CVD is reduced by 10% for every additional cup of green tea intake.
Taking together, green tea may be used as a functional food of healthy adults with a higher risk CVD.
However, long term and a large amount of green tea consumption should be taken with care to prevent toxicity.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Antioxidant beverages: green tea intake and coronary artery disease by Ohmori R1, Kondo K2, Momiyama Y3.(PubMed)
(2) Effects of green tea intake on the development of coronary artery disease by Sano J1, Inami S, Seimiya K, Ohba T, Sakai S, Takano T, Mizuno K.(PubMed)
Herbal Turmeric Suppresses Osteoarthritis
Osteoarthritis (OA) one of the most common forms of arthritis that affects over 25 25 million people in the United States is a chronic inflammatory disease of the joints due to wear and tear over time.
The characteristics of osteoarthritis are aching pain, stiffness, or difficulty of moving the joint or joints. The pain usually gets worse in a change of weather, at night and in the advanced diseases, the pain can occur even at rest.
Conventionally, treatment of osteoarthritis (OA) focuses on pain relief and improved physical function through pharmacological, nonpharmacological, and surgical treatments.
Most common risk factors associated with the onset of OA include genetic preposition, being overweight or obese, previous joint injury and repetitive movements or injuries to joints (such as a fracture, surgery or ligament tears).
However, most people with some of the risk factors have never developed the disease.
Dr. Sally Thomas, the lead scientist in the treatment of OA patients wrote, "As current treatment options in OA are very limited, OA patients would benefit greatly from some ability to self-manage their condition".
And, "For overweight/obese patients, weight reduction, ideally incorporating exercise, is paramount. The association between metabolic syndrome, type-2 diabetes, and OA risk or progression may partly explain the apparent benefit of dietary-lipid modification resulting from increased consumption of long-chain omega-3 fatty acids from oily fish/fish oil supplements. A strong association between OA and raised serum cholesterol together with clinical effects in statin users suggests a potential benefit of reduction of cholesterol by dietary means".
In other words, depending on the causes, patients may be recommended to a specific treatment.
Turmeric is a perennial plant in the genus Curcuma, belonging to the family Zingiberaceae, native to tropical South Asia.
The herb has been used in traditional medicine as anti-oxidant, hypoglycemic, colorant, antiseptic, wound healing agent, and for the treatment of flatulence, bloating, and appetite loss, ulcers, eczema, inflammations, etc.
With an aim to find a potential compound for the treatment of osteoarthritis (OA), researchers examined the Curene®, a bioavailable formulation of turmeric anti-inflammatory properties.
The randomized, double-blind, placebo-controlled, parallel-group included 50 subjects aged between 40 and 75 years who were suffering from unilateral or bilateral OA of the knee for greater than 3 months according to American College of Rheumatology (ACR) criteria.
The treatment group received 500mg Curene® once daily and the other group received a placebo.
According to the results from the Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) score, Curene® treated group showed a statistically significant reduction of pain score compared to placebo without inducing any adverse effects.
In other words, Curene® 500mg not only reduced pain, stiffness but also improved physical functioning in subjects suffering from knee OA.
In order to reveal more information of turmeric anti OA activity, researchers investigated LI73014F2 is a novel composition prepared from extracts of Terminalia chebula fruit, Curcuma longa rhizome, and Boswellia serrata gum resin in the inhibition of 5-Lipoxygenase (5-LOX).
Where activated enzyme 5-Lipoxygenase (5-LOX), has been found to induce pain in patients with OA.
In a 90-day randomized, placebo-controlled double-blind study included 105 particpants divded into three groups: placebo (n = 35), 200 mg/day of LI73014F2 (n = 35), and 400 mg/day of LI73014F2 (n = 35).
According to the results from tested assays obtained from the baseline (day 0) and on day 14 ± 3, 30 ± 3, 60 ± 3, and at the end of the study (day 90 ± 3), all doses of LI73014F2 conferred a strong effect in pain relief, improved physical function, and quality of life in OA patients, compared to the baseline.
Dr. Karlapudi V, the lead scientist said, "preclinical and clinical data together strongly suggest that the herbal formulation LI73014F2 is a safe and effective intervention for management of joint discomfort, demonstrating efficacy as early as 14 days".
Based on the findings, turmeric processed a high amount of bioactive curcumin used alone or combined with other herbal medicines may be considered supplements for the treatment of osteoarthritis (OA), pending to the confirmation of the larger sample size and multicenter human study.
Intake of turmeric in the form of supplement should be taken with extreme care to prevent overdose acute liver toxicity.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
Osteoarthritis
(1) A Randomized, Double Blind, Placebo Controlled, Parallel-Group Study to Evaluate the Safety and Efficacy of Curene® versus Placebo in Reducing Symptoms of Knee OA by Panda SK1, Nirvanashetty S2, Parachur VA3, Mohanty N4, Swain T. (PubMed)
(2) A Placebo-Controlled Double-Blind Study Demonstrates the Clinical Efficacy of a Novel Herbal Formulation for Relieving Joint Discomfort in Human Subjects with Osteoarthritis of Knee by Karlapudi V1, Prasad Mungara AVV2, Sengupta K3, Davis BA4, Raychaudhuri SP. (PubMed)
(3) What is the evidence for a role for diet and nutrition in osteoarthritis? by Sally Thomas,1 Heather Browne,1 Ali Mobasheri,2,3,4 and Margaret P Rayman. (PMC)
The characteristics of osteoarthritis are aching pain, stiffness, or difficulty of moving the joint or joints. The pain usually gets worse in a change of weather, at night and in the advanced diseases, the pain can occur even at rest.
Conventionally, treatment of osteoarthritis (OA) focuses on pain relief and improved physical function through pharmacological, nonpharmacological, and surgical treatments.
Most common risk factors associated with the onset of OA include genetic preposition, being overweight or obese, previous joint injury and repetitive movements or injuries to joints (such as a fracture, surgery or ligament tears).
However, most people with some of the risk factors have never developed the disease.
Dr. Sally Thomas, the lead scientist in the treatment of OA patients wrote, "As current treatment options in OA are very limited, OA patients would benefit greatly from some ability to self-manage their condition".
And, "For overweight/obese patients, weight reduction, ideally incorporating exercise, is paramount. The association between metabolic syndrome, type-2 diabetes, and OA risk or progression may partly explain the apparent benefit of dietary-lipid modification resulting from increased consumption of long-chain omega-3 fatty acids from oily fish/fish oil supplements. A strong association between OA and raised serum cholesterol together with clinical effects in statin users suggests a potential benefit of reduction of cholesterol by dietary means".
In other words, depending on the causes, patients may be recommended to a specific treatment.
Turmeric is a perennial plant in the genus Curcuma, belonging to the family Zingiberaceae, native to tropical South Asia.
The herb has been used in traditional medicine as anti-oxidant, hypoglycemic, colorant, antiseptic, wound healing agent, and for the treatment of flatulence, bloating, and appetite loss, ulcers, eczema, inflammations, etc.
With an aim to find a potential compound for the treatment of osteoarthritis (OA), researchers examined the Curene®, a bioavailable formulation of turmeric anti-inflammatory properties.
The randomized, double-blind, placebo-controlled, parallel-group included 50 subjects aged between 40 and 75 years who were suffering from unilateral or bilateral OA of the knee for greater than 3 months according to American College of Rheumatology (ACR) criteria.
The treatment group received 500mg Curene® once daily and the other group received a placebo.
According to the results from the Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) score, Curene® treated group showed a statistically significant reduction of pain score compared to placebo without inducing any adverse effects.
In other words, Curene® 500mg not only reduced pain, stiffness but also improved physical functioning in subjects suffering from knee OA.
In order to reveal more information of turmeric anti OA activity, researchers investigated LI73014F2 is a novel composition prepared from extracts of Terminalia chebula fruit, Curcuma longa rhizome, and Boswellia serrata gum resin in the inhibition of 5-Lipoxygenase (5-LOX).
Where activated enzyme 5-Lipoxygenase (5-LOX), has been found to induce pain in patients with OA.
In a 90-day randomized, placebo-controlled double-blind study included 105 particpants divded into three groups: placebo (n = 35), 200 mg/day of LI73014F2 (n = 35), and 400 mg/day of LI73014F2 (n = 35).
According to the results from tested assays obtained from the baseline (day 0) and on day 14 ± 3, 30 ± 3, 60 ± 3, and at the end of the study (day 90 ± 3), all doses of LI73014F2 conferred a strong effect in pain relief, improved physical function, and quality of life in OA patients, compared to the baseline.
Dr. Karlapudi V, the lead scientist said, "preclinical and clinical data together strongly suggest that the herbal formulation LI73014F2 is a safe and effective intervention for management of joint discomfort, demonstrating efficacy as early as 14 days".
Based on the findings, turmeric processed a high amount of bioactive curcumin used alone or combined with other herbal medicines may be considered supplements for the treatment of osteoarthritis (OA), pending to the confirmation of the larger sample size and multicenter human study.
Intake of turmeric in the form of supplement should be taken with extreme care to prevent overdose acute liver toxicity.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
Osteoarthritis
(1) A Randomized, Double Blind, Placebo Controlled, Parallel-Group Study to Evaluate the Safety and Efficacy of Curene® versus Placebo in Reducing Symptoms of Knee OA by Panda SK1, Nirvanashetty S2, Parachur VA3, Mohanty N4, Swain T. (PubMed)
(2) A Placebo-Controlled Double-Blind Study Demonstrates the Clinical Efficacy of a Novel Herbal Formulation for Relieving Joint Discomfort in Human Subjects with Osteoarthritis of Knee by Karlapudi V1, Prasad Mungara AVV2, Sengupta K3, Davis BA4, Raychaudhuri SP. (PubMed)
(3) What is the evidence for a role for diet and nutrition in osteoarthritis? by Sally Thomas,1 Heather Browne,1 Ali Mobasheri,2,3,4 and Margaret P Rayman. (PMC)
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