Oxidative stress is a medical condition caused by a long-term imbalance of the ratio of free radicals and antioxidants in the body.
In other words, overexpression of free radicals and depletion of antioxidant enzymes produced by the host body are the most common cause of oxidative stress.
Oxidative stress occurs when the abundant and unstable free radicals start a chain reaction by stealing or donating their unpaired electrons in the outermost ring to stable atoms, leading to a cascade that cannot be stopped until all electrons are paired or inhibited by antioxidant.
Oxidative stress is dealy to oxidized protein, lipid and cause cell damage that have been linking to chronic diseases such as cardiovascular disease, diabetes, and cancer.
Certain risk factors such as unhealthy lifestyle such as smoking, an unhealthy diet with fewer fruits and vegetables, certain medical conditions such as chronic inflammatory disease and environmental factors such as pollution and radiation have linked to the onset of oxidative stress.
Believe it or not, people with a weakened immune system are more prone to oxidative stress compared to a healthy individual. Therefore, intake of antioxidants from the dietary sources may be necessary.
Dr. JA Knight in the investigation of free radicals, antioxidants, and immune system wrote, " oxidative stress may be detrimental in acquired immunity by activation of nuclear factor kappa B, which governs gene expression involving various cytokines, chemokines, and cell adhesion molecules, among others"
And "antioxidant supplementation essentially reverses several age-associated immune deficiencies, resulting in increased levels of interleukin-2, elevated numbers of total lymphocytes and T-cell subsets, enhanced mitogen responsiveness, increased killer cell activity, augmented antibody response to antigen stimulation, decreased lipid peroxidation, and decreased prostaglandin synthesis".
Alliin (S-allyl-L-cysteine-S-oxide) is a phytochemical compound sulfoxide,. a derivative of the amino acid cysteine, belonging to the class of sulfur compounds, found abundantly in fresh garlic and onion.
With an aim to find a potential compound for the treatment of diseases associated with oxidative stress, scientists investigated the effects of garlic active compounds, diallyl disulfide (DADS), diallyl sulfide (DAS) and alliin against Dengue virus (DENV).
Based on the tested assays, alliin reduced inflammation and affected the oxidative stress response by blocking the immune system response involved in the production of pro-inflammatory cytokines against the oxidative stress.
Furthermore, in cancer cells, pretreatment of alliin exerted a toxic effect on several mammalian cells in vitro in a dose-dependent manner.
In other words, alliin demonstrated significant cytotoxicity against cancer cells by killing them before they can reproduce.
More precisely, alliin-induced cancer cell apoptosis by increasing caspase-3 expression, DNA fragmentation, cell cycle arrest, ROS generation, GSH depletion.
The findings suggested that alliin modulated oxidative stress (the production of antioxidant and free radicals) depending on the body needs without causing harm to the healthy cells.
Taken altogether, alliin may be considered supplements for the prevention and treatment of diseases associated with oxidative stress, depending on the confirmation of the larger sample size and multicenter human study.
Intake of alliin in the form of supplement should be taken with extreme care to prevent overdose acute liver toxicity.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) In situ allicin generation using targeted alliinase delivery for inhibition of MIA PaCa-2 cells via epigenetic changes, oxidative stress and cyclin-dependent kinase inhibitor (CDKI) expression by Chhabria SV1, Akbarsha MA, Li AP, Kharkar PS, Desai KB. (PubMed)
(2) Garlic Organosulfur Compounds Reduce Inflammation and Oxidative Stressduring Dengue Virus Infection by Hall A1, Troupin A2, Londono-Renteria B3, Colpitts TM4. (PubMed)
(3) Review: Free radicals, antioxidants, and the immune system by JA Knight. (Annual of Clinical & Laboratory Science)
Sunday, September 15, 2019
Herbal Ginger, the Best Chemo Preventive Functional Food
Scientists may have found a natural ingredient which processed chemopreventive effects, with no side effects, according to study.
Chemoprevention is a general term used to describe the use of nontoxic natural chemicals and supplements for the treatment of cancer without inducing side effects.
The subjects of chemoprevention have under intensive studies over the last many years due to the side effects of chemo drugs. Natural chemopreventive agents have emerged as a promising and pragmatic medical approach to reduce the risk of cancer.
Most natural chemical compounds have been found to process the activity similar to those of conventional medicines for the treatment of cancer such as antioxidative, anti-inflammatory activity, induction of phase II enzymes, apoptosis, and cell cycle arrest.
For example: Curcumin found in turmeric in animal models has been shown to protect against skin, oral, intestinal, and colon carcinogenesis and also to suppress angiogenesis and metastasis.
Furthermore, the administration also found that the chemical compound process the ability to cancer proliferation by cell cycle arrest, induced apoptosis and activated the phase carcinogen-detoxifying enzymes.
Moreover, curcumin has a capability to inhibit carcinogen bioactivation via suppression of specific cytochrome P450 isozymes associated with the biotransformation of medication that causes drug toxicities, reduced pharmacological effect, and adverse drug reactions.
Dr. Pan MH the lead scientist in the cancer team at the National Kaohsiung Marine University wrote, "Many mechanisms have been shown to account for the anticarcinogenic actions of natural dietary compounds; attention has recently been focused on intracellular-signaling cascades as common molecular targets for various chemopreventive natural dietary compounds".
And, "In this critical review, we will summarize current knowledge on natural dietary compounds that act through the signaling pathways and modulate gene expression to induce detoxifying enzymes, programmed cell death, anti-inflammatory, and anti-proliferative effects, thus providing evidence for these substances in cancer chemopreventive action".
Ginger (Zingiber officinale) or ginger root, the second superfood used for thousands of years by mankind, is the genus Zingiber, belonging to the family Zingiberaceae, native to Tamil.
The root has been used in traditional and Chinese medicine for the treatment of dyspepsia, gastroparesis, constipation, edema, difficult urination, colic, etc.
With an aim to find a natural ingredient which processes chemopreventive effects with no side effects, researchers examined the ginger effect on cancer prevention.
Ginger exerted a significant activity against cancer onset through several mechanisms, including free radical scavenging, antioxidant pathways, alteration of gene expressions, and induction of apoptosis.
Ginger protects the integrity and viability of the cell by decreasing tumor initiation, promotion, and progression.
Dr. Baliga MS, the lead scientist,. after taking other factors into accounts wrote, "The above-mentioned mechanisms of ginger seem to be promising for cancer prevention; however, further clinical studies are warranted to assess the efficacy and safety of ginger".
In order to reveal more information about the ginger anticancer activity, researchers evaluated the effects of [6]-gingerol aspirinate (GAS) against colorectal cancers.
GAS exerts enhanced anti-cancer properties in vitro and superior gastroprotective effects in mice by inhibiting the protein associated with the production of proinflammatory cytokines.
More importantly, GAS was also able to survive stomach acid and decomposed in intestinal linings or after absorption to simultaneously release of [6]-gingerol.
Dr. Zhu Y, the lead researcher said, "Our results demonstrate the enhanced anticancer properties along with gastroprotective effects of GAS, suggesting that GAS can be a therapeutic equivalent for ASA in inflammatory and proliferative diseases without the deleterious effects on stomach mucosa".
Take all together, ginger processed high amounts of the bioactive compound may be considered a functional alternative for chemoprevention, pending to the confirmation of large sample size and multicenter human study.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma ISSN 0975-6299.
Sources
(1) Update on the chemopreventive effects of ginger and its phytochemicals by Baliga MS1, Haniadka R, Pereira MM, D'Souza JJ, Pallaty PL, Bhat HP, Popuri S. (PubMed)
(2) Gastroprotective [6]-Gingerol Aspirinate as a Novel Chemopreventive Prodrug of Aspirin for Colon Cancer by Zhu Y1, Wang F1,2, Zhao Y1, Wang P1, Sang S. (PubMed)
(3) Chemopreventive effects of natural dietary compounds on cancer development by Pan MH1, Ho CT. (PubMed)
(4) Cancer chemopreventive effects of curcumin by Surh YJ1, Chun KS. (PubMed)
Chemoprevention is a general term used to describe the use of nontoxic natural chemicals and supplements for the treatment of cancer without inducing side effects.
The subjects of chemoprevention have under intensive studies over the last many years due to the side effects of chemo drugs. Natural chemopreventive agents have emerged as a promising and pragmatic medical approach to reduce the risk of cancer.
Most natural chemical compounds have been found to process the activity similar to those of conventional medicines for the treatment of cancer such as antioxidative, anti-inflammatory activity, induction of phase II enzymes, apoptosis, and cell cycle arrest.
For example: Curcumin found in turmeric in animal models has been shown to protect against skin, oral, intestinal, and colon carcinogenesis and also to suppress angiogenesis and metastasis.
Furthermore, the administration also found that the chemical compound process the ability to cancer proliferation by cell cycle arrest, induced apoptosis and activated the phase carcinogen-detoxifying enzymes.
Moreover, curcumin has a capability to inhibit carcinogen bioactivation via suppression of specific cytochrome P450 isozymes associated with the biotransformation of medication that causes drug toxicities, reduced pharmacological effect, and adverse drug reactions.
Dr. Pan MH the lead scientist in the cancer team at the National Kaohsiung Marine University wrote, "Many mechanisms have been shown to account for the anticarcinogenic actions of natural dietary compounds; attention has recently been focused on intracellular-signaling cascades as common molecular targets for various chemopreventive natural dietary compounds".
And, "In this critical review, we will summarize current knowledge on natural dietary compounds that act through the signaling pathways and modulate gene expression to induce detoxifying enzymes, programmed cell death, anti-inflammatory, and anti-proliferative effects, thus providing evidence for these substances in cancer chemopreventive action".
Ginger (Zingiber officinale) or ginger root, the second superfood used for thousands of years by mankind, is the genus Zingiber, belonging to the family Zingiberaceae, native to Tamil.
The root has been used in traditional and Chinese medicine for the treatment of dyspepsia, gastroparesis, constipation, edema, difficult urination, colic, etc.
With an aim to find a natural ingredient which processes chemopreventive effects with no side effects, researchers examined the ginger effect on cancer prevention.
Ginger exerted a significant activity against cancer onset through several mechanisms, including free radical scavenging, antioxidant pathways, alteration of gene expressions, and induction of apoptosis.
Ginger protects the integrity and viability of the cell by decreasing tumor initiation, promotion, and progression.
Dr. Baliga MS, the lead scientist,. after taking other factors into accounts wrote, "The above-mentioned mechanisms of ginger seem to be promising for cancer prevention; however, further clinical studies are warranted to assess the efficacy and safety of ginger".
In order to reveal more information about the ginger anticancer activity, researchers evaluated the effects of [6]-gingerol aspirinate (GAS) against colorectal cancers.
GAS exerts enhanced anti-cancer properties in vitro and superior gastroprotective effects in mice by inhibiting the protein associated with the production of proinflammatory cytokines.
More importantly, GAS was also able to survive stomach acid and decomposed in intestinal linings or after absorption to simultaneously release of [6]-gingerol.
Dr. Zhu Y, the lead researcher said, "Our results demonstrate the enhanced anticancer properties along with gastroprotective effects of GAS, suggesting that GAS can be a therapeutic equivalent for ASA in inflammatory and proliferative diseases without the deleterious effects on stomach mucosa".
Take all together, ginger processed high amounts of the bioactive compound may be considered a functional alternative for chemoprevention, pending to the confirmation of large sample size and multicenter human study.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma ISSN 0975-6299.
Sources
(1) Update on the chemopreventive effects of ginger and its phytochemicals by Baliga MS1, Haniadka R, Pereira MM, D'Souza JJ, Pallaty PL, Bhat HP, Popuri S. (PubMed)
(2) Gastroprotective [6]-Gingerol Aspirinate as a Novel Chemopreventive Prodrug of Aspirin for Colon Cancer by Zhu Y1, Wang F1,2, Zhao Y1, Wang P1, Sang S. (PubMed)
(3) Chemopreventive effects of natural dietary compounds on cancer development by Pan MH1, Ho CT. (PubMed)
(4) Cancer chemopreventive effects of curcumin by Surh YJ1, Chun KS. (PubMed)
Saturday, September 14, 2019
Green Tea and its Bioactive Egallocatechin-3-gallate (EGCG) in Reduced Risk, Progression and Treatment of Lupus
Green tea may have a therapeutic and positive effect in reduced risk and treatment of systemic lupus erythematosus (SLE), some scientists suggested.
Green tea is a precious drink processes numbers of health benefit known to almost everyone in Asia and the Western world.
The systemic lupus erythematosus (SLE) is an autoimmune disease characterized by the body's immune system abnormal function in attacking healthy tissue in many parts of the body.
In the study of patient with lupus nephritis induced by SLE, researchers found that intake of green tea epigallocatechin-3-gallate (EGCG), the major bioactive polyphenol displayed a strong antioxidant effect in reduced expression of reactive oxygen species inactivated the activity of pro-inflammatory factors nuclear factor-kappa B (NF-κB), a protein complex-mediated inflammatory responses under stress stimuli in induction of inflammation.
Further analysis, also indicated that application of green tea EGCG decreased levels of interleukin (IL)-1β and IL-18, the inflammatory cytokines which were found to have a closed link to inflammation and correlated with systemic lupus erythematosus (SLE).
Moreover, in the evaluation of 12-week-old New Zealand black/white (NZB/W) F1 lupus-prone mice treated daily with EGCG by gavage until sacrificed at 34 weeks old, researchers at the National Defense Medical Center found that green tea ingestion exerts a strong effect in prevented proteinuria, renal function impairment, and severe renal lesions through increased repression of antioxidant mediated by renal nuclear factor E2-related factor 2 (Nrf2) and enhanced natural antioxidant of glutathione peroxidase produced by the host body.
The overexpression of antioxidant activity participated by green tea EGCG also ameliorated the free radical in expression of renal oxidative stress, through reduced NF-κB activation in production of inflammatory cytokine and increased anti-inflammatory NLRP3 mRNA/protein expression and mature caspase-1, IL-1β, and IL-18 in response to inflammation caused by immune abnormal activity in systemic lupus erythematosus (SLE).
The result of the study also found that green tea EGCG also enhanced splenic regulatory T (Treg) cell activity in maintain immunologic homeostasis and inhibited autoimmunity.
Additional study of green tea, epigallocatechin-3-gallate (EGCG) effect in lupus, researchers suggested that green tea exerted a profound anti-inflammatory activity on immune cells through inhibiting the immune-stimulated phosphoinositide 3-kinase (PI3K)/Akt/mammalian target of rapamycin (mTOR) pathway in the attenuated inflammatory response.
In fact, the expression of green tea EGCG also reduced the production of nitric oxide (NO) and other inflammatory mediators including iNOS expression, supernatant NO and interleukin-6 in the initiation of mesangial cells inflammation in the kidney under abnormal immunity in patients of systemic lupus erythematosus (SLE).
Dr. Peairs A, after taking into account of other co-founders said, " EGCG attenuated inflammation in MRL/lpr mouse mesangial cells via the PI3K/Akt/mTOR pathway" and "EGCG to regulate inflammation and control autoimmune disease".
The result of above differentiation was supported by the study conducted by the Medical College of Georgia in the evaluation of the green tea polyphenol, (-)-epigallocatechin-3-gallate (EGCG), affects autoantigen expression in human cells.
Dr. Hsu S, at the end of the experiment, postulated that green tea bioactive polyphenols EGCG inhibited the transcription and translation of major autoantigens, including SS-B/La, SS-A/Ro, coilin, DNA topoisomerase I, and alpha-fodrin through its anti-inflammatory and anti-apoptotic tissue effects.
Taken together, green tea and its bioactive component epigallocatechin-3-gallate (EGCG) may be considered as a functional food in reduced risk and progression and combined with conventional therapy for the treatment of systemic lupus erythematosus (SLE). However, the intake of green tea supplement should be taken with care in prevented liver acute toxicity.
For More information about yoga lessons tailor to a complete well being for women, please visit: YOGA For Women
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You. How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Epigallocatechin-3-gallate prevents lupus nephritis development in mice via enhancing the Nrf2 antioxidant pathway and inhibiting NLRP3 inflammasome activation by Tsai PY1, Ka SM, Chang JM, Chen HC, Shui HA, Li CY, Hua KF, Chang WL, Huang JJ, Yang SS, Chen A.(PubMed)
(2) Epigallocatechin-3-gallate (EGCG) attenuates inflammation in MRL/lpr mouse mesangial cells by Peairs A1, Dai R, Gan L, Shimp S, Rylander MN, Li L, Reilly CM.(PubMed)
(3) Inhibition of autoantigen expression by (-)-epigallocatechin-3-gallate (the major constituent of green tea) in normal human cells by Hsu S1, Dickinson DP, Qin H, Lapp C, Lapp D, Borke J, Walsh DS, Bollag WB, Stöppler H, Yamamoto T, Osaki T, Schuster G.(PubMed)
Green tea is a precious drink processes numbers of health benefit known to almost everyone in Asia and the Western world.
The systemic lupus erythematosus (SLE) is an autoimmune disease characterized by the body's immune system abnormal function in attacking healthy tissue in many parts of the body.
In the study of patient with lupus nephritis induced by SLE, researchers found that intake of green tea epigallocatechin-3-gallate (EGCG), the major bioactive polyphenol displayed a strong antioxidant effect in reduced expression of reactive oxygen species inactivated the activity of pro-inflammatory factors nuclear factor-kappa B (NF-κB), a protein complex-mediated inflammatory responses under stress stimuli in induction of inflammation.
Further analysis, also indicated that application of green tea EGCG decreased levels of interleukin (IL)-1β and IL-18, the inflammatory cytokines which were found to have a closed link to inflammation and correlated with systemic lupus erythematosus (SLE).
Moreover, in the evaluation of 12-week-old New Zealand black/white (NZB/W) F1 lupus-prone mice treated daily with EGCG by gavage until sacrificed at 34 weeks old, researchers at the National Defense Medical Center found that green tea ingestion exerts a strong effect in prevented proteinuria, renal function impairment, and severe renal lesions through increased repression of antioxidant mediated by renal nuclear factor E2-related factor 2 (Nrf2) and enhanced natural antioxidant of glutathione peroxidase produced by the host body.
The overexpression of antioxidant activity participated by green tea EGCG also ameliorated the free radical in expression of renal oxidative stress, through reduced NF-κB activation in production of inflammatory cytokine and increased anti-inflammatory NLRP3 mRNA/protein expression and mature caspase-1, IL-1β, and IL-18 in response to inflammation caused by immune abnormal activity in systemic lupus erythematosus (SLE).
The result of the study also found that green tea EGCG also enhanced splenic regulatory T (Treg) cell activity in maintain immunologic homeostasis and inhibited autoimmunity.
Additional study of green tea, epigallocatechin-3-gallate (EGCG) effect in lupus, researchers suggested that green tea exerted a profound anti-inflammatory activity on immune cells through inhibiting the immune-stimulated phosphoinositide 3-kinase (PI3K)/Akt/mammalian target of rapamycin (mTOR) pathway in the attenuated inflammatory response.
In fact, the expression of green tea EGCG also reduced the production of nitric oxide (NO) and other inflammatory mediators including iNOS expression, supernatant NO and interleukin-6 in the initiation of mesangial cells inflammation in the kidney under abnormal immunity in patients of systemic lupus erythematosus (SLE).
Dr. Peairs A, after taking into account of other co-founders said, " EGCG attenuated inflammation in MRL/lpr mouse mesangial cells via the PI3K/Akt/mTOR pathway" and "EGCG to regulate inflammation and control autoimmune disease".
The result of above differentiation was supported by the study conducted by the Medical College of Georgia in the evaluation of the green tea polyphenol, (-)-epigallocatechin-3-gallate (EGCG), affects autoantigen expression in human cells.
Dr. Hsu S, at the end of the experiment, postulated that green tea bioactive polyphenols EGCG inhibited the transcription and translation of major autoantigens, including SS-B/La, SS-A/Ro, coilin, DNA topoisomerase I, and alpha-fodrin through its anti-inflammatory and anti-apoptotic tissue effects.
Taken together, green tea and its bioactive component epigallocatechin-3-gallate (EGCG) may be considered as a functional food in reduced risk and progression and combined with conventional therapy for the treatment of systemic lupus erythematosus (SLE). However, the intake of green tea supplement should be taken with care in prevented liver acute toxicity.
For More information about yoga lessons tailor to a complete well being for women, please visit: YOGA For Women
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You. How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Epigallocatechin-3-gallate prevents lupus nephritis development in mice via enhancing the Nrf2 antioxidant pathway and inhibiting NLRP3 inflammasome activation by Tsai PY1, Ka SM, Chang JM, Chen HC, Shui HA, Li CY, Hua KF, Chang WL, Huang JJ, Yang SS, Chen A.(PubMed)
(2) Epigallocatechin-3-gallate (EGCG) attenuates inflammation in MRL/lpr mouse mesangial cells by Peairs A1, Dai R, Gan L, Shimp S, Rylander MN, Li L, Reilly CM.(PubMed)
(3) Inhibition of autoantigen expression by (-)-epigallocatechin-3-gallate (the major constituent of green tea) in normal human cells by Hsu S1, Dickinson DP, Qin H, Lapp C, Lapp D, Borke J, Walsh DS, Bollag WB, Stöppler H, Yamamoto T, Osaki T, Schuster G.(PubMed)
Green Tea In the Prevention and Treatment of Acute and Chronic Constipation
Green tea may have a therapeutic and positive effect in reduced risk and treatment of acute and chronic constipation, some scientists suggested.
Constipation is a condition of hard to pass stool or not passing stool frequently, affecting 1/6 people over 12 years old in Canada.
In the examine the effects of Pu-erh tea on constipation in ICR mice induced by carbon injection researchers found that mice in control group without administrated Pu-erh green tea expressed a significant weight loss, food and water intake in compared to experiment group.
In compared to first black stool time of normal group of 90 min, control (injection of carbon) of 221 min and bisacodyl treatment group (100 mg/kg in control group) of 118 min, mice in control group treated with green tea at doses of 200, 400 and 800 mg/kg showed an improved stool passing time of 178, 155 and 139 min, respectively.
Importantly, the application of green tea Pu-erh also expressed a strong increase of serum levels of
1. Motilin (MTL) in the blood stream in stimulated the contraction of the fundus and antrum and accelerated gastric emptying;
2. Gastrin, a peptide hormone in the stimulated secretion of gastric acid (HCl) by the parietal cells of the stomach in improved gastric motility;
3. Endothelin (ET), a peptide hormone with function in the contraction of rat stomach strips, rat colon, and guinea pig ileum;
4. Acetylcholine enzyme (AchE) chemical released by motor neurons of the nervous system in order to activate muscles;
5. Substance P (SP) an amino-acids peptide in the induction of rapid contraction of the smooth muscle of the digestive tract and
6. Vasoactive intestinal peptide (VIP), a potent vasodilator, in regulated smooth muscle activity and blood flow in the gastrointestinal tract.
And the decrease of somatostatin (SS) hormone in reduced gastric acid secretion and emission of gastrointestinal hormones, such as gastrin.
Additionally, in comparison of 2 types of commonly used osmotic laxative polyethylene glycol (PEG), namely PEG with electrolytes mixed with water and PEG without electrolytes mixed with tea or other sources such as juice and coffee for taste, researchers at the Pirkanmaan Erikoislääkäripalvelu conducted a randomized, double-blind, parallel-group study at ten private assisted-living facilities or communal nursing homes in Finland. Selected patients were.required to have used isotonic PEG at a stable dose without any other treatment for constipation (except for Plantago ovata seeds) for at least 2 weeks prior to a run-in period and randomly assigned receive hypotonic PEG or continued to receive isotonic PEG, both dissolved in water, 12 g once or twice daily or once every other day, for 4 weeks, found that the mean (SD) weekly stool frequencies are not different in both hypotonic and isotonic PEG groups, although soft or normal stool consistency of 70% was higher in the hypotonic PEG group in compared to 52% in isotonic PEG group.
Moreover, both products are considered safe without inducing stool straining or gastrointestinal symptoms, although the level of sodium was statistically and significantly lower in the hypotonic PEG group at the last day of testing of the study in compared to another group.
Dr. Seinelä L, after taking into account other co-factors said, "Both treatments appear safe, well-tolerated and, when dissolved in water, well accepted by the majority of the patients. When desired, switching from isotonic to hypotonic PEG can safely take place in elderly individuals without compromising efficacy".
However, a total of 1,705 female Japanese dietetic students aged 18-20 years and free of current disease studies suggested the intake of tea is associated to constipation(3) without mentioning types of tea used in the surveys.
According to the theory of traditional Chinese medicine, green tea is yin in nature with function in relieving indigestion and smoothed bowel movements through promotion of fluid production(4) and constipation is a result of overexpression of yang or deficiency of yin, therefore, we do believe, the tea mentioned in the study were red, black or herbal tea with yang sufficiency.
Taken together, green tea may be considered as a functional food for the prevention and treatment of constipation. Intake of green tea extracts should be taken with exceptional care due to toxicity reported in the medical literature.
For More information about yoga lessons tailor to a complete well being for women, please visit: YOGA BURN
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Component analysis of Pu-erh and its anti-constipation effects by Li G1, Wang Q1, Qian Y1, Zhou Y1, Wang R1, Zhao X1.(PubMed)
(2) Comparison of polyethylene glycol with and without electrolytes in the treatment of constipation in elderly institutionalized patients: a randomized, double-blind, parallel-group study by Seinelä L1, Sairanen U, Laine T, Kurl S, Pettersson T, Happonen P.(PubMed)
(3) Dietary intake in relation to self-reported constipation among Japanese women aged 18-20 years by Murakami K1, Okubo H, Sasaki S.(PubMed)
(4) History of Green Tea by Tao de Wan
Constipation is a condition of hard to pass stool or not passing stool frequently, affecting 1/6 people over 12 years old in Canada.
In the examine the effects of Pu-erh tea on constipation in ICR mice induced by carbon injection researchers found that mice in control group without administrated Pu-erh green tea expressed a significant weight loss, food and water intake in compared to experiment group.
In compared to first black stool time of normal group of 90 min, control (injection of carbon) of 221 min and bisacodyl treatment group (100 mg/kg in control group) of 118 min, mice in control group treated with green tea at doses of 200, 400 and 800 mg/kg showed an improved stool passing time of 178, 155 and 139 min, respectively.
Importantly, the application of green tea Pu-erh also expressed a strong increase of serum levels of
1. Motilin (MTL) in the blood stream in stimulated the contraction of the fundus and antrum and accelerated gastric emptying;
2. Gastrin, a peptide hormone in the stimulated secretion of gastric acid (HCl) by the parietal cells of the stomach in improved gastric motility;
3. Endothelin (ET), a peptide hormone with function in the contraction of rat stomach strips, rat colon, and guinea pig ileum;
4. Acetylcholine enzyme (AchE) chemical released by motor neurons of the nervous system in order to activate muscles;
5. Substance P (SP) an amino-acids peptide in the induction of rapid contraction of the smooth muscle of the digestive tract and
6. Vasoactive intestinal peptide (VIP), a potent vasodilator, in regulated smooth muscle activity and blood flow in the gastrointestinal tract.
And the decrease of somatostatin (SS) hormone in reduced gastric acid secretion and emission of gastrointestinal hormones, such as gastrin.
Additionally, in comparison of 2 types of commonly used osmotic laxative polyethylene glycol (PEG), namely PEG with electrolytes mixed with water and PEG without electrolytes mixed with tea or other sources such as juice and coffee for taste, researchers at the Pirkanmaan Erikoislääkäripalvelu conducted a randomized, double-blind, parallel-group study at ten private assisted-living facilities or communal nursing homes in Finland. Selected patients were.required to have used isotonic PEG at a stable dose without any other treatment for constipation (except for Plantago ovata seeds) for at least 2 weeks prior to a run-in period and randomly assigned receive hypotonic PEG or continued to receive isotonic PEG, both dissolved in water, 12 g once or twice daily or once every other day, for 4 weeks, found that the mean (SD) weekly stool frequencies are not different in both hypotonic and isotonic PEG groups, although soft or normal stool consistency of 70% was higher in the hypotonic PEG group in compared to 52% in isotonic PEG group.
Moreover, both products are considered safe without inducing stool straining or gastrointestinal symptoms, although the level of sodium was statistically and significantly lower in the hypotonic PEG group at the last day of testing of the study in compared to another group.
Dr. Seinelä L, after taking into account other co-factors said, "Both treatments appear safe, well-tolerated and, when dissolved in water, well accepted by the majority of the patients. When desired, switching from isotonic to hypotonic PEG can safely take place in elderly individuals without compromising efficacy".
However, a total of 1,705 female Japanese dietetic students aged 18-20 years and free of current disease studies suggested the intake of tea is associated to constipation(3) without mentioning types of tea used in the surveys.
According to the theory of traditional Chinese medicine, green tea is yin in nature with function in relieving indigestion and smoothed bowel movements through promotion of fluid production(4) and constipation is a result of overexpression of yang or deficiency of yin, therefore, we do believe, the tea mentioned in the study were red, black or herbal tea with yang sufficiency.
Taken together, green tea may be considered as a functional food for the prevention and treatment of constipation. Intake of green tea extracts should be taken with exceptional care due to toxicity reported in the medical literature.
For More information about yoga lessons tailor to a complete well being for women, please visit: YOGA BURN
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Component analysis of Pu-erh and its anti-constipation effects by Li G1, Wang Q1, Qian Y1, Zhou Y1, Wang R1, Zhao X1.(PubMed)
(2) Comparison of polyethylene glycol with and without electrolytes in the treatment of constipation in elderly institutionalized patients: a randomized, double-blind, parallel-group study by Seinelä L1, Sairanen U, Laine T, Kurl S, Pettersson T, Happonen P.(PubMed)
(3) Dietary intake in relation to self-reported constipation among Japanese women aged 18-20 years by Murakami K1, Okubo H, Sasaki S.(PubMed)
(4) History of Green Tea by Tao de Wan
Friday, September 13, 2019
Green Tea In Reducing the Risk of Subarachnoid Hemorrhage (SAH)
Green tea may have a therapeutic and positive effect in reduced risk hemorrhage, some scientists suggested.
Green tea is a precious drink processes numbers of health benefit known to almost everyone in Asia and the Western world.
Hemorrhage is a condition of vessel rupture, leading to bleeding within the brain tissue.
In the investigation of the effects of green tea polyphenols intake and the risk of subarachnoid hemorrhage (SAH) study, researchers at the Henan Institute of Science and Technology found that
administration of green tea reduced the early onset of SAH through prevented alteration of mitochondrial membrane potential to the basal level.
Further analysis, also suggested that green tea pre-treatment also decreased the production of Adenosine triphosphate(APT) content, a vasoactive compound found in high concentrations after subarachnoid hemorrhage and the cytochrome c level to induced cell death in the brain cortex after 12 hours in the tested models.
These result suggested that green tea administration not only exerted a significant neuroprotective effect against the polarization of mitochondrial membrane potential and prevented the production of certain proteins and enzymes in the induction of brain damage.
Indeed, over the course of study of a total of 180 mice, 8 (4.4%) died during the experiment, 5 (8.3%) in the SAH group, 3 (5.0%) in the tea polyphenols pretreated model, and 0 in the control group.
And the differentiation of the neurological scores observed for mice with SAH was significantly lower than that of the sham group from 6 h to 72 h after SAH occurrence.
Additionally, pretreatment with tea polyphenols expressed a significant decrease in activity lactic acid dehydrogenase (LDH) levels in the bloodstream, an indication of brain tissue injury and damage in compared to the untreated SAH group.
Dr. Mo H, the lead scientist after taking into account others con-founders, said, "After pretreatment with tea polyphenols, the neurological outcome was also improved(through various implications)".
Interestingly, in a designed to determine the effects of consumption of green tea in reduced risk for subarachnoid hemorrhage (SAH) in a case-control study consisting incident SAH cases of n=201 matched by age (+/-2 years) and gender to hospital (n=201) and community controls (n=201) from April 1992 to March 1997, researchers at the Aichi Prefectural College of Nursing and Health suggested that habitual green tea consumption is associated inversely in risk of subarachnoid hemorrhage (SAH).
People who drank one or more cup of green tea per day scored a significant lower risk of 60.3% compared to non-tea drinking group of 70.9%.
More specifically, testing subjects who consumed <1, and >or=1 time per day showed a strong ameliorated risk with an adjusted overall risk ratio of 0.74 and 0.56 respectively, in compared nondaily green tea drinkers.
Okamoto K suggested that risk of subarachnoid hemorrhage (SAH) is significant reduced linearly depending to numbers of a cup of green intake per day.
Taken together, green tea as powerful antioxidant activity may be considered as a functional food in reduced risk of subarachnoid hemorrhage (SAH) and used a combination with standard medicine for post-treatment of the incidence.
For More information on yoga lessons tailor to a complete well being for women, please visit: YOGA BURN
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Neuroprotective effect of tea polyphenols on oxyhemoglobin induced subarachnoid hemorrhage in mice by Mo H1, Chen Y, Huang L, Zhang H, Li J, Zhou W.(PubMed)
(2) Habitual green tea consumption and risk of an aneurysmal rupture subarachnoid hemorrhage: a case-control study in Nagoya, Japan by Okamoto K1.(PubMed)
(3) Dietary antioxidant intake and risk of an aneurysmal rupture subarachnoid hemorrhage in Japan by Okamoto K1, Horisawa R.(PubMed)
Green tea is a precious drink processes numbers of health benefit known to almost everyone in Asia and the Western world.
Hemorrhage is a condition of vessel rupture, leading to bleeding within the brain tissue.
In the investigation of the effects of green tea polyphenols intake and the risk of subarachnoid hemorrhage (SAH) study, researchers at the Henan Institute of Science and Technology found that
administration of green tea reduced the early onset of SAH through prevented alteration of mitochondrial membrane potential to the basal level.
Further analysis, also suggested that green tea pre-treatment also decreased the production of Adenosine triphosphate(APT) content, a vasoactive compound found in high concentrations after subarachnoid hemorrhage and the cytochrome c level to induced cell death in the brain cortex after 12 hours in the tested models.
These result suggested that green tea administration not only exerted a significant neuroprotective effect against the polarization of mitochondrial membrane potential and prevented the production of certain proteins and enzymes in the induction of brain damage.
Indeed, over the course of study of a total of 180 mice, 8 (4.4%) died during the experiment, 5 (8.3%) in the SAH group, 3 (5.0%) in the tea polyphenols pretreated model, and 0 in the control group.
And the differentiation of the neurological scores observed for mice with SAH was significantly lower than that of the sham group from 6 h to 72 h after SAH occurrence.
Additionally, pretreatment with tea polyphenols expressed a significant decrease in activity lactic acid dehydrogenase (LDH) levels in the bloodstream, an indication of brain tissue injury and damage in compared to the untreated SAH group.
Dr. Mo H, the lead scientist after taking into account others con-founders, said, "After pretreatment with tea polyphenols, the neurological outcome was also improved(through various implications)".
Interestingly, in a designed to determine the effects of consumption of green tea in reduced risk for subarachnoid hemorrhage (SAH) in a case-control study consisting incident SAH cases of n=201 matched by age (+/-2 years) and gender to hospital (n=201) and community controls (n=201) from April 1992 to March 1997, researchers at the Aichi Prefectural College of Nursing and Health suggested that habitual green tea consumption is associated inversely in risk of subarachnoid hemorrhage (SAH).
People who drank one or more cup of green tea per day scored a significant lower risk of 60.3% compared to non-tea drinking group of 70.9%.
More specifically, testing subjects who consumed <1, and >or=1 time per day showed a strong ameliorated risk with an adjusted overall risk ratio of 0.74 and 0.56 respectively, in compared nondaily green tea drinkers.
Okamoto K suggested that risk of subarachnoid hemorrhage (SAH) is significant reduced linearly depending to numbers of a cup of green intake per day.
Taken together, green tea as powerful antioxidant activity may be considered as a functional food in reduced risk of subarachnoid hemorrhage (SAH) and used a combination with standard medicine for post-treatment of the incidence.
For More information on yoga lessons tailor to a complete well being for women, please visit: YOGA BURN
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Neuroprotective effect of tea polyphenols on oxyhemoglobin induced subarachnoid hemorrhage in mice by Mo H1, Chen Y, Huang L, Zhang H, Li J, Zhou W.(PubMed)
(2) Habitual green tea consumption and risk of an aneurysmal rupture subarachnoid hemorrhage: a case-control study in Nagoya, Japan by Okamoto K1.(PubMed)
(3) Dietary antioxidant intake and risk of an aneurysmal rupture subarachnoid hemorrhage in Japan by Okamoto K1, Horisawa R.(PubMed)
Herbal Turmeric, a Natural Prevention and Treatment of Hyperglycemia
Hyperglycemia is a condition of abnormally high levels of glucose in the bloodstream. The condition also is a hallmark of diabetes. Another hallmark is insulin resistance.
Postprandial blood glucose is the levels taken after 2 hours of a meal, generally at the approximate peak value in patients with diabetes.
Most cases of hyperglycemia are the results of poor diet and glucose management in patients with diabetes. However, missing insulin injection and improper use of insulin injection are also found in some patients.
Management of postprandial blood glucose has become an important feature for diabetics against the risk of microvascular (retinopathy, nephropathy, and neuropathy) and cardiovascular disease (CVD).
Diabetes is a medical and chronic disease characterized by insufficient insulin entering the bloodstream to regulate the glucose as a result of the cells in pancreas died off or receptor sites clogged up by fat and cholesterol.
Most common symptoms of hyperglycemia are increased thirst, headache, frequent peeing, fatigue with blood sugar more than 180 mg/dL.
Depending on the blood glucose levels, some patient may also experience symptoms of trouble concentrating, blurred vision and weight loss.
However, some researchers suggested that poor diet with high saturated and trans fat, red meat and processed foods is one of the major and preventable risk factors associated with the onset of the condition in the Western world compared to a traditional diet.
Dr. David Hefner in the concern of the risk of diabetes in patients who are fans of the Western diet wrote, "The typical Western diet-red meat, high-fat dairy products, refined grains and desserts-may increase your chances for Type 2 diabetes" and "That's what researchers at the Harvard School of Public Health have found and reported in the Annals of Internal Medicine."
The doctor continued, "The news isn't particularly shocking but offers a new view on the health risks of a typical Western diet as a whole, rather than simply attacking elements within the diet such as fatty foods".
Turmeric is a perennial plant in the genus Curcuma, belongings to the family Zingiberaceae, native to tropical South Asia.
The herb has been used in traditional medicine as anti-oxidant, hypoglycemic, colorant, antiseptic, wound healing agent, and for the treatment of flatulence, bloating, and appetite loss, ulcers, eczema, inflammations, etc.
On findings a potential compound for lowering blood glucose, researchers examined the efficacy of curcumin, antihyperglycemic activity.
By searching the medical database in PubMed from 1998 to 2013, associated with the role of curcumin in the development and progression of hyperglycemia and insulin resistance, researchers found that
* Curcumin inhibited the uptakes of blood glucose level by reducing the liver glucose production and suppressing abnormally high blood sugar-induced inflammatory state.
Furthermore, stimulation of glucose uptake associated hyperglycemia caused by overexpression of GLUT4, GLUT2 and GLUT3 genes that facilitate glucose movement across cell membranes was also attenuated by curcumin.
Activation of AMP kinase and promotion of PPAR ligand-binding activity involved in stimulated glucose uptake and lipid oxidation were also reduced by the administration of the bioactive compound.
Additionally, curcumin also inhibited the expression hyperglycemia by modulating the insulin secretion from pancreatic tissues, improving pancreatic cell function, thus reducing the risk of insulin resistance.
Based on the findings, researchers wrote, "Curcumin has antihyperglycemic and insulin sensitizer effects. Thereby, more studies evaluating the effects of curcumin on hyperglycemic state and insulin resistance in related disorders such as diabetes are recommended".
Taken altogether, turmeric processed abundantly bioactive compound curcumin may be considered supplements for the prevention and treatment of hyperglycemia, pending to the confirmation of the larger sample size and multicenter human study.
Intake of turmeric in the form of supplement should be taken with extreme care to prevent overdose acute liver toxicity.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You. How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Phytotherapeutic activity of curcumol: Isolation, GC-MS identification, and assessing potentials against acute and subchronic hyperglycemia, tactile allodynia, and hyperalgesia by Raafat KM1, Omar AG. (PubMed)
(2) Anti-hyperglycemic and insulin sensitizer effects of turmeric and its principle constituent curcumin by Ghorbani Z1, Hekmatdoost A2, Mirmiran P. (PubMed)
(3) Western Diet Linked to Type 2 Diabetes by David Hefner. (PMC)
Postprandial blood glucose is the levels taken after 2 hours of a meal, generally at the approximate peak value in patients with diabetes.
Most cases of hyperglycemia are the results of poor diet and glucose management in patients with diabetes. However, missing insulin injection and improper use of insulin injection are also found in some patients.
Management of postprandial blood glucose has become an important feature for diabetics against the risk of microvascular (retinopathy, nephropathy, and neuropathy) and cardiovascular disease (CVD).
Diabetes is a medical and chronic disease characterized by insufficient insulin entering the bloodstream to regulate the glucose as a result of the cells in pancreas died off or receptor sites clogged up by fat and cholesterol.
Most common symptoms of hyperglycemia are increased thirst, headache, frequent peeing, fatigue with blood sugar more than 180 mg/dL.
Depending on the blood glucose levels, some patient may also experience symptoms of trouble concentrating, blurred vision and weight loss.
However, some researchers suggested that poor diet with high saturated and trans fat, red meat and processed foods is one of the major and preventable risk factors associated with the onset of the condition in the Western world compared to a traditional diet.
Dr. David Hefner in the concern of the risk of diabetes in patients who are fans of the Western diet wrote, "The typical Western diet-red meat, high-fat dairy products, refined grains and desserts-may increase your chances for Type 2 diabetes" and "That's what researchers at the Harvard School of Public Health have found and reported in the Annals of Internal Medicine."
The doctor continued, "The news isn't particularly shocking but offers a new view on the health risks of a typical Western diet as a whole, rather than simply attacking elements within the diet such as fatty foods".
Turmeric is a perennial plant in the genus Curcuma, belongings to the family Zingiberaceae, native to tropical South Asia.
The herb has been used in traditional medicine as anti-oxidant, hypoglycemic, colorant, antiseptic, wound healing agent, and for the treatment of flatulence, bloating, and appetite loss, ulcers, eczema, inflammations, etc.
On findings a potential compound for lowering blood glucose, researchers examined the efficacy of curcumin, antihyperglycemic activity.
By searching the medical database in PubMed from 1998 to 2013, associated with the role of curcumin in the development and progression of hyperglycemia and insulin resistance, researchers found that
* Curcumin inhibited the uptakes of blood glucose level by reducing the liver glucose production and suppressing abnormally high blood sugar-induced inflammatory state.
Furthermore, stimulation of glucose uptake associated hyperglycemia caused by overexpression of GLUT4, GLUT2 and GLUT3 genes that facilitate glucose movement across cell membranes was also attenuated by curcumin.
Activation of AMP kinase and promotion of PPAR ligand-binding activity involved in stimulated glucose uptake and lipid oxidation were also reduced by the administration of the bioactive compound.
Additionally, curcumin also inhibited the expression hyperglycemia by modulating the insulin secretion from pancreatic tissues, improving pancreatic cell function, thus reducing the risk of insulin resistance.
Based on the findings, researchers wrote, "Curcumin has antihyperglycemic and insulin sensitizer effects. Thereby, more studies evaluating the effects of curcumin on hyperglycemic state and insulin resistance in related disorders such as diabetes are recommended".
Taken altogether, turmeric processed abundantly bioactive compound curcumin may be considered supplements for the prevention and treatment of hyperglycemia, pending to the confirmation of the larger sample size and multicenter human study.
Intake of turmeric in the form of supplement should be taken with extreme care to prevent overdose acute liver toxicity.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You. How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Phytotherapeutic activity of curcumol: Isolation, GC-MS identification, and assessing potentials against acute and subchronic hyperglycemia, tactile allodynia, and hyperalgesia by Raafat KM1, Omar AG. (PubMed)
(2) Anti-hyperglycemic and insulin sensitizer effects of turmeric and its principle constituent curcumin by Ghorbani Z1, Hekmatdoost A2, Mirmiran P. (PubMed)
(3) Western Diet Linked to Type 2 Diabetes by David Hefner. (PMC)
Thursday, September 12, 2019
Cucumber, The Best for the Treatment of Hyperlipidemia, According to Human Trial
Hyperlipidemia is a condition of abnormally high blood lipid in the bloodstream a major cause of plaque accumulation on the arterial wall that leads to the increased risk of heart disease and stroke.
Cholesterol produced either by the liver or fat intake is essential to aid the digestive system in digesting foods and absorbing nutrient before passing them to other parts of the body, build a strong cell wall, produce vitamin D and steroid hormone.
There are 2 main types of cholesterol. The low-density lipoprotein (LDL) which carries the aforementioned function and the high-density lipoprotein (HDL)which returns the cholesterol back to the liver for reuse in the future.
The healthy blood cholesterol ratio of total blood cholesterol of LDL/ HDL is any numbers that are less than 4.
People with high blood cholesterol are asymptomatic. Conventionally, the condition can be lowered by regular intake of blood cholesterol-lowering medicine.
Most common risk factors that cause the onset of high blood cholesterol are unhealthy diet and physical inactivity.
Some researchers in the examination of the widespread high blood cholesterol over the past few decades probably are associated with the promotion of the high-fat diet in the US.
Dr. Cole TG, the lead scientist wrote," In normals, dietary cholesterol increases LDL production and decreases LDL receptor-related LDL clearance, resulting in elevations in LDL cholesterol levels of approximately 30 mg/dL".
Therefore, by changing behaviors in lifestyle, you may just be doing fine without medication. Please sure you tale to your doctor before withholding.
The cucumber plant is a species of Cucumis Sativus, belongs to the family Cucurbitaceae and native to Western Asia. It is a creeping vine with roots in the ground and grows up with the support of frames.
On finding a natural compound for the treatment of hyperlipidemia with no side effects, researchers examined the efficacy of Cucumber (Cucumis sativus) seed, used traditionally as a lipid-lowering nutritional supplement.
The randomized double-blind placebo-controlled clinical trial included hyperlipidemic patients with inclusion criteria randomly and equally assigned to either Cucumis or placebo groups or one medicinal or placebo capsule, once daily with food for 6 weeks.
According to the tested assays obtained from 23 patients in Cucumis group and 23 patients in the placebo group completed the study, cucumber seed extract-treated group showed a significant reduction of total cholesterol, and BMI index compared to baseline taken before the treatment
The extract also increased the levels of high-density lipoprotein (HLD) compared to placebo.
More precisely, at a concentration of daily dose of 500 mg, the consumption of C. sativus seed extract daily, exerted strong effects on serum lipid profile in tested adult hyperlipidemic patients.
In other words, daily injection at the ceratin dose may have a desirable effect in the prevention of hyperlipidemia in facilitating the onset of cholesterol build-up on the arteries and risk of cardiovascular disease.
Based on the results, researchers said, "Cucumber seed could be considered as a food supplement for treatment of dyslipidemia".
Taken altogether, cucumber may be used for the prevention and treatment of hyperlipidemia, pending to the confirmation of the larger sample size and multicenter human study.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Evaluation of the Effects of Cucumis sativus Seed Extract on Serum Lipids in Adult Hyperlipidemic Patients: A Randomized Double-Blind Placebo-Controlled Clinical Trial by Soltani R1, Hashemi M2, Farazmand A1, Asghari G3, Heshmat-Ghahdarijani K2, Kharazmkia A4, Ghanadian SM. (PubMed)
(2) Effects of high cholesterol high fat diet on plasma lipoproteins in familial hypercholesterolemia by Cole TG, Pfleger B, Hitchins O, Schonfeld G. (PubMed)
Cholesterol produced either by the liver or fat intake is essential to aid the digestive system in digesting foods and absorbing nutrient before passing them to other parts of the body, build a strong cell wall, produce vitamin D and steroid hormone.
There are 2 main types of cholesterol. The low-density lipoprotein (LDL) which carries the aforementioned function and the high-density lipoprotein (HDL)which returns the cholesterol back to the liver for reuse in the future.
The healthy blood cholesterol ratio of total blood cholesterol of LDL/ HDL is any numbers that are less than 4.
People with high blood cholesterol are asymptomatic. Conventionally, the condition can be lowered by regular intake of blood cholesterol-lowering medicine.
Most common risk factors that cause the onset of high blood cholesterol are unhealthy diet and physical inactivity.
Some researchers in the examination of the widespread high blood cholesterol over the past few decades probably are associated with the promotion of the high-fat diet in the US.
Dr. Cole TG, the lead scientist wrote," In normals, dietary cholesterol increases LDL production and decreases LDL receptor-related LDL clearance, resulting in elevations in LDL cholesterol levels of approximately 30 mg/dL".
Therefore, by changing behaviors in lifestyle, you may just be doing fine without medication. Please sure you tale to your doctor before withholding.
The cucumber plant is a species of Cucumis Sativus, belongs to the family Cucurbitaceae and native to Western Asia. It is a creeping vine with roots in the ground and grows up with the support of frames.
On finding a natural compound for the treatment of hyperlipidemia with no side effects, researchers examined the efficacy of Cucumber (Cucumis sativus) seed, used traditionally as a lipid-lowering nutritional supplement.
The randomized double-blind placebo-controlled clinical trial included hyperlipidemic patients with inclusion criteria randomly and equally assigned to either Cucumis or placebo groups or one medicinal or placebo capsule, once daily with food for 6 weeks.
According to the tested assays obtained from 23 patients in Cucumis group and 23 patients in the placebo group completed the study, cucumber seed extract-treated group showed a significant reduction of total cholesterol, and BMI index compared to baseline taken before the treatment
The extract also increased the levels of high-density lipoprotein (HLD) compared to placebo.
More precisely, at a concentration of daily dose of 500 mg, the consumption of C. sativus seed extract daily, exerted strong effects on serum lipid profile in tested adult hyperlipidemic patients.
In other words, daily injection at the ceratin dose may have a desirable effect in the prevention of hyperlipidemia in facilitating the onset of cholesterol build-up on the arteries and risk of cardiovascular disease.
Based on the results, researchers said, "Cucumber seed could be considered as a food supplement for treatment of dyslipidemia".
Taken altogether, cucumber may be used for the prevention and treatment of hyperlipidemia, pending to the confirmation of the larger sample size and multicenter human study.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Evaluation of the Effects of Cucumis sativus Seed Extract on Serum Lipids in Adult Hyperlipidemic Patients: A Randomized Double-Blind Placebo-Controlled Clinical Trial by Soltani R1, Hashemi M2, Farazmand A1, Asghari G3, Heshmat-Ghahdarijani K2, Kharazmkia A4, Ghanadian SM. (PubMed)
(2) Effects of high cholesterol high fat diet on plasma lipoproteins in familial hypercholesterolemia by Cole TG, Pfleger B, Hitchins O, Schonfeld G. (PubMed)
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