Artichoke may be used as a functional remedy for the treatment of type 2 diabetes with no side effects, according to studies.
Type 2 diabetes is a medical disease characterized by not enough insulin in the bloodstream due to dismissed pancreas function or in properly use the insulin of the body.
In other words, type 2 diabetes is caused by the beta cell which is responsible for the production of insulin died off or the clogged up of the insulin receptor sites, which allow the cell to bind with insulin in the blood to transform glucose to energy.
The hallmark of type 2 diabetes is insulin resistance.
Types 2 diabetes is a common disease of adults in the Western world. According to the statistics provided by the Centers for Disease Control and Prevention (CDC), over 100 million U.S. adults are now living with diabetes or prediabetes.
And, in 2015, 30.3 million Americans or 9.4 percent of the U.S. population have diabetes.
The disease has caused a significant economic burden in the world. In the US, the annual economic cost for each individual with type 2 diabetes is $11,917.
In fact, the direct diabetes costs in a country’s gross domestic product (GDP) per capita, the USA stood out as having particularly high costs, compared to other countries.
Some researchers suggested that the widespread type 2 diabetes in the overweight population in the US may be correlated to the promotion of the Western diet over the past few decades.
Dr. Lu Qi, and colleagues in the examination of the Western diet in types 2 diabetics wrote, "The Western dietary pattern was not associated with diabetes risk among those with a lower GRS."
And, "In addition, we found that intakes of processed meat, red meat, and heme iron, which characterized the Western dietary pattern, showed significant interactions with GRS in relation to diabetes risk (P for interaction = 0.029, 0.02, and 0.0004, respectively). The diet-diabetes associations were more evident among men with a high GRS (≥12) than in those with a low GRS".
The results indirectly suggested that people who follow the Western diet with a genetic risk score (GRS) are at an increased risk of type 2 diabetes.
Artichoke is a perennial thistle of Cynara cardunculus species of the Cynara genus, belonging to the family Carduoideae native to Southern Europe around the Mediterranean.
The herbal plant has been used in traditional medicine as a liver protective and detoxified agent, and to treat digestive disorders, abdominal pain gas and bloating, etc.
Scientists on finding a natural ingredient for the treatment of diabetes examined the artichoke (JA) potential in attenuating lipid disturbances and insulin resistance (IR) in an animal model.
Wistar rats selected for the study were fed a control diet, a 60 % fructose-enriched diet (FRU), or an FRU with 10 % JA (n 6-7) for 4 weeks. An oral glucose tolerance test was carried out on day 21.
Injection of JA showed a significant effect on improving the expression of the genes associated with fibrosis and inflammation and insulin resistance according to the global gene expression analyses and oral glucose tolerance test, respectively.
Dr. Chang WC, the lead scientist after taking into account co and confounder suggested that 10 % JA supplementation may be beneficial for the prevention of the onset of diabetes.
Furthermore, in order to reveal more information about the artichoke anti-diabetes effect, researchers conducted a randomized, double-blinded, placebo-controlled study on 60 subjects with impaired fasting glucose (IFG), impaired glucose tolerance (IGT), or newly diagnosed type 2 diabetes.
The selected subjects were randomly assigned to either a group that ingested 40 g of a Jerusalem artichoke and fermented soybean powder mixture (19.45 g each) daily or a group that received a placebo for 12 weeks.
Group treated with supplementation with the Jerusalem artichoke and fermented soybean powder mixture reduced the levels of fasting glucose (p < 0.001) and FFAs (p = 0.034), glucose at 60 min.
According to the homeostasis model assessment, the supplement also inhibits the insulin resistance (p = 0.018), and the urinary 8-epi-prostaglandin F2α (8-epi-PGF2α) level, a marker of free radical-catalyzed lipid peroxidation.
Moreover, the change of glucose at 120 min (r = 0.472, p = 0.027) and the glucose under the curve (AUC) were positively correlated with the reduction of plasma malondialdehyde, an indication of oxidative stress.
The finding clearly suggested the efficacy of the consumption of a Jerusalem artichoke and fermented soybean powder mixture against the overexpression of glucose for 12 weeks, particularly, in the newly diagnosed type 2 diabetes.
Taken altogether, artichoke used alone or combined with other herbal products may be considered functional remedies for the prevention and treatment of type 2 diabetes, pending to the confirmation of larger sample size and multicenter human study.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
References
(1) Beneficial effects of soluble dietary Jerusalem artichoke (Helianthus tuberosus) in the prevention of the onset of type 2 diabetes and non-alcoholic fatty liver disease in high-fructose diet-fed rats by Chang WC1, Jia H2, Aw W2, Saito K2, Hasegawa S3, Kato H1. (PubMed)
(2)The effects of Jerusalem artichoke and fermented soybean powder mixture supplementation on blood glucose and oxidative stress in subjects with prediabetes or newly diagnosed type 2 diabetes.
Ahn HY1, Kim M1, Seo CR2, Yoo HJ3, Lee SH4, Lee JH. (PubMed)
(3) Genetic predisposition, Western dietary pattern, and the risk of type 2 diabetes in men by Lu Qi, Marilyn C Cornelis, Cuilin Zhang, Rob M van Dam, and Frank B Hu. (PMC)
Sunday, October 27, 2019
Herbal Arnica, the Potential Colon Cancer Functional Herb
Herb Arnica may be the next target of the pharmaceutical companies to identify a single ingredient medicine for the treatment of colon cancer, some scientists suggested.
Colon cancer is a slow and predictable condition characterized by irregular cell growth on the colon tissue.
The cause of colon cancer is a result of the alternation of DNA of the cells in the colon.
Most cases of colon cancer start at the cells on the surface of the inner lining of the colon tissue. At this stage, the tumor is very small and does not cause any symptoms.
However, at the later stage, colon cancer may cause symptoms of a change of bowel habits, severe rectal bleeding or blood in your stool and persistently abdominal pain.
If you experience some of the above symptoms that last more than 4 weeks, please check with your doctor to rule out the possibility of colon cancer.
According to the statistic, the 5-year survival rate of people with localized stage colorectal cancer is 90% and only 39% of patients are diagnosed at this early stage.
Researchers do not know why people with the same health condition, family history and diet pattern, some are susceptible to colon cells DNA alternation while others do not.
Out of a number of risk factors, the genetic preposition has been under intensifying studies by many scientists.
Dr.Glaser EM in finding the genetic mutation associated with the risk colon cancer said, "Colorectal cancer is one of the most common malignancies in the United States. Although both genetic and environmental factors play a role in colorectal tumorigenesis" and "single genes that confer susceptibility to familial adenomatous polyposis (FAP) and hereditary nonpolyposis colorectal cancer (HNPCC). Because these genes are inherited in an autosomal dominant fashion, offspring of carriers have a 50% chance of inheriting the gene mutation and its associated risk".
The genetic mutation hereditary nonpolyposis colorectal cancer (HNPCC).genes has a prevalence rate of 1 in 500, and causes about 2% to 3% of all colorectal cancers.
More importantly, genetic testing for the FAP and HNPCC genes is now available for everyone.
Arnica is a herbaceous species, genus perennial, belonging to the family Asteraceae, native to Europe and Asia.
The plant has been used in herbal medicine for centuries to treat strains, sprains, and bruises.
Colon Cancer is defined as a condition of the abnormal proliferation of cells in the colon.
Besides containing contain helenalin as it main ingredient used as an anti-inflammatory agent in herbal medicine, herbal Arnica also contains 11,13- dihydrohelenaline, chamissonolid, Sesquiterpene lactone, lignans of the furofuran, dibenzylbutyrolactone, dibenzylbutyrolactol types, pinoresinol, epipinoresinol, phillygenin, matairesinol, nortrachelogenin, and nortracheloside, six dibenzylbutyrolactol derivatives.
In the concerns of the aberrant crypt foci (ACF) and colon-rectal mucosal epithelial cell proliferation in patients with colon cancer, researchers at the University of São Paulo examine the anti-colon cancer of chemical compound isolated from the Lychnophora ericoides Mart. (Brazilian herbal arnica).
50 included in the study were randomly assigned to the followings Fifty male Wistar rats were randomly divided into 5 groups.
* The groups G1 to G4 were given 4 injections of the carcinogen 1,2-dimethylhydrazine (DMH).
* The G2 group received Lychnophora ericoides (LE) extracts for 6 wks.
* The groups G3 and G4 received LE for 4 wk and 2 wk, respectively, at the postinitiation and initiation phases of colonic carcinogenesis.
* The group G5 was the control.
42 days after the first injections of DMH for the neoplastic induction, researchers found that
* Groups G1 demonstrated an increase in the number of aberrant crypt foci (ACF) and cancer cell proliferation induced by DMH.
* Group G4 after treatment of LE inhibited a clinically significant decrease in the number of aberrant crypt foci (ACF) and attenuated the increase of cancer cell proliferation induced by DMH.
These results suggested that Lychnophora ericoides extracts were effective against the development of colon cancer by suppressing the initiation and progression of colonic carcinogenesis.
Continuously, to differentiate the effect of herbal Arnica effects in the inhibition of cancers, researchers examine the cytotoxicity of 21 flavonoids and 5 sesquiterpene lactones, isolated from herbal Arnica in a human small cell lung carcinoma cell line, and in COLO 320, a human colorectal cancer cell line.
Compared to cisplatin, a novel chemo drug, most flavonoids showed moderate to low cytotoxicity against COLO 320 cancer cell line.
However, flavone jaceosidin of the sesquiterpene lactones was found to be the most effective compound.in displaying the cytotoxicity.
The application of the maximum half-life concentration of 1.0 microM exerted the most cytotoxic effect against COLO 320.
Compared to GLC4, COLO 320 was more sensitive than for many flavonoids (especially for flavones).
The finding strongly indicated that herbal Arnica bioactive compounds process potential activity in inhibiting the onset and progression of colon cancer.
Therefore, herbal Arnica containing abundant bioactive compounds may have potential in reducing the risk and treatment of colon cancer, depending on the confirmation of the large sample size and multicenter in the human study.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
References
(1) The protective role of Lychnophora ericoides Mart. (Brazilian arnica) in 1,2-dimethylhydrazine-induced experimental colon carcinogenesis by Fernandes CR, Turatti A, Gouvea DR, Gobbo-Neto L, Diniz A, Ribeiro-Silva A, Lopes NP, Garcia SB.(PubMed)
(2) Cytotoxicity of flavonoids and sesquiterpene lactones from Arnica species against the GLC4 and the COLO 320 cell lines by Woerdenbag HJ, Merfort I, Passreiter CM, Schmidt TJ, Willuhn G, van Uden W, Pras N, Kampinga HH, Konings AW.(PubMed)
(3) Inherited predisposition to colon cancer by Glaser EM. (PubMed)
Colon cancer is a slow and predictable condition characterized by irregular cell growth on the colon tissue.
The cause of colon cancer is a result of the alternation of DNA of the cells in the colon.
Most cases of colon cancer start at the cells on the surface of the inner lining of the colon tissue. At this stage, the tumor is very small and does not cause any symptoms.
However, at the later stage, colon cancer may cause symptoms of a change of bowel habits, severe rectal bleeding or blood in your stool and persistently abdominal pain.
If you experience some of the above symptoms that last more than 4 weeks, please check with your doctor to rule out the possibility of colon cancer.
According to the statistic, the 5-year survival rate of people with localized stage colorectal cancer is 90% and only 39% of patients are diagnosed at this early stage.
Researchers do not know why people with the same health condition, family history and diet pattern, some are susceptible to colon cells DNA alternation while others do not.
Out of a number of risk factors, the genetic preposition has been under intensifying studies by many scientists.
Dr.Glaser EM in finding the genetic mutation associated with the risk colon cancer said, "Colorectal cancer is one of the most common malignancies in the United States. Although both genetic and environmental factors play a role in colorectal tumorigenesis" and "single genes that confer susceptibility to familial adenomatous polyposis (FAP) and hereditary nonpolyposis colorectal cancer (HNPCC). Because these genes are inherited in an autosomal dominant fashion, offspring of carriers have a 50% chance of inheriting the gene mutation and its associated risk".
The genetic mutation hereditary nonpolyposis colorectal cancer (HNPCC).genes has a prevalence rate of 1 in 500, and causes about 2% to 3% of all colorectal cancers.
More importantly, genetic testing for the FAP and HNPCC genes is now available for everyone.
Arnica is a herbaceous species, genus perennial, belonging to the family Asteraceae, native to Europe and Asia.
The plant has been used in herbal medicine for centuries to treat strains, sprains, and bruises.
Colon Cancer is defined as a condition of the abnormal proliferation of cells in the colon.
Besides containing contain helenalin as it main ingredient used as an anti-inflammatory agent in herbal medicine, herbal Arnica also contains 11,13- dihydrohelenaline, chamissonolid, Sesquiterpene lactone, lignans of the furofuran, dibenzylbutyrolactone, dibenzylbutyrolactol types, pinoresinol, epipinoresinol, phillygenin, matairesinol, nortrachelogenin, and nortracheloside, six dibenzylbutyrolactol derivatives.
In the concerns of the aberrant crypt foci (ACF) and colon-rectal mucosal epithelial cell proliferation in patients with colon cancer, researchers at the University of São Paulo examine the anti-colon cancer of chemical compound isolated from the Lychnophora ericoides Mart. (Brazilian herbal arnica).
50 included in the study were randomly assigned to the followings Fifty male Wistar rats were randomly divided into 5 groups.
* The groups G1 to G4 were given 4 injections of the carcinogen 1,2-dimethylhydrazine (DMH).
* The G2 group received Lychnophora ericoides (LE) extracts for 6 wks.
* The groups G3 and G4 received LE for 4 wk and 2 wk, respectively, at the postinitiation and initiation phases of colonic carcinogenesis.
* The group G5 was the control.
42 days after the first injections of DMH for the neoplastic induction, researchers found that
* Groups G1 demonstrated an increase in the number of aberrant crypt foci (ACF) and cancer cell proliferation induced by DMH.
* Group G4 after treatment of LE inhibited a clinically significant decrease in the number of aberrant crypt foci (ACF) and attenuated the increase of cancer cell proliferation induced by DMH.
These results suggested that Lychnophora ericoides extracts were effective against the development of colon cancer by suppressing the initiation and progression of colonic carcinogenesis.
Continuously, to differentiate the effect of herbal Arnica effects in the inhibition of cancers, researchers examine the cytotoxicity of 21 flavonoids and 5 sesquiterpene lactones, isolated from herbal Arnica in a human small cell lung carcinoma cell line, and in COLO 320, a human colorectal cancer cell line.
Compared to cisplatin, a novel chemo drug, most flavonoids showed moderate to low cytotoxicity against COLO 320 cancer cell line.
However, flavone jaceosidin of the sesquiterpene lactones was found to be the most effective compound.in displaying the cytotoxicity.
The application of the maximum half-life concentration of 1.0 microM exerted the most cytotoxic effect against COLO 320.
Compared to GLC4, COLO 320 was more sensitive than for many flavonoids (especially for flavones).
The finding strongly indicated that herbal Arnica bioactive compounds process potential activity in inhibiting the onset and progression of colon cancer.
Therefore, herbal Arnica containing abundant bioactive compounds may have potential in reducing the risk and treatment of colon cancer, depending on the confirmation of the large sample size and multicenter in the human study.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
References
(1) The protective role of Lychnophora ericoides Mart. (Brazilian arnica) in 1,2-dimethylhydrazine-induced experimental colon carcinogenesis by Fernandes CR, Turatti A, Gouvea DR, Gobbo-Neto L, Diniz A, Ribeiro-Silva A, Lopes NP, Garcia SB.(PubMed)
(2) Cytotoxicity of flavonoids and sesquiterpene lactones from Arnica species against the GLC4 and the COLO 320 cell lines by Woerdenbag HJ, Merfort I, Passreiter CM, Schmidt TJ, Willuhn G, van Uden W, Pras N, Kampinga HH, Konings AW.(PubMed)
(3) Inherited predisposition to colon cancer by Glaser EM. (PubMed)
Saturday, October 26, 2019
Green Tea, The Functional Beverage Which Protects the Stomach Against Gastric Ulcer
Green tea may have a therapeutic and positive effect in reducing the risk and treatment of gastric ulcers, some scientists suggested.
Gastric ulcers are sores that develop in the lining of the stomach as a result of a bacterial infection or by overproduction of stomach acid. In other words, gastric ulcer is a condition characterized by open sores developed in the stomach, affecting the function of the stomach.
There are a set of factors that cause a gastric ulcer, including the infection of Helicobacter pylori (H. pylori), frequent use of anti-inflammatory medicine, aging, smoking and excessive alcohol drinking
Some researchers suggested that people who have radiation therapy for stomach cancer are also a higher risk of gastric ulcer development.
According to the study "Are genetic influences on peptic ulcer dependent or independent of genetic influences for Helicobacter pylori infection?" by the Veterans Affairs Medical Center and Baylor College of Medicine. "Genetic influences are of moderate importance for liability to peptic ulcer disease. Genetic influences for peptic ulcer are independent of genetic influences important for acquiring H. pylori infection".
If you are experiencing the symptoms of dull pain in the stomach. weight loss. refuse to eat because of pain. persistent gastrointestinal discomforts, acid reflux, and heartburn, you may have a gastric ulcer. Please make sure that you check with your doctor to rule out the possibility.
Green tea, a precious drink processes a numbers of health benefits known to almost everyone in Asia and the Western world.
In the testing of healing of the hydroalcoholic extract including ethyl acetate fraction, (GEAc) and epigallocatechin gallate (EGCG) from green tea (GEt) in the risk of gastric ulcer induced by application of 80 % acetic acid on serosal mucosa of rats, researchers showed that application of the extract after 7 days inhibited ulcer area by exhibiting the antioxidant activity in reducing the free radical overexpression.
Furthermore, application of the hydroalcoholic extract also inhibited the oxidative stress that cause gastric damage by injection of acetic acid by enhancing the production of antioxidant enzyme GSH, superoxide dismutase (SOD) and Glutathione-S-transferase (GST) enzymes and ameliorating the production of lipid hydroperoxides (LOOH), a free radical in precipitated ulcer development by withdrawing electrons from the lipids in cell membranes.
Additional analysis also suggested that rats fed with green tea (GEt) improved the capacity of mucin content in gastric juice which has been found at reduced levels in rats with an ulcer after infecting of acetic acid.
Interestingly, injection of green tea (GEt) also decreased inflammatory infiltration of Myeloperoxidase (MPO) and N-acetylglucosaminidase (NAG) which has been used as biomarkers in the measurement of severity in some diseases including gastric ulcer.
Importantly, the application did not alter gastric acid secretion and induced acute toxicity.
Dr. Borato DG, the lead authors, after taking into account con-founders said, "GEt had a pronounced antiulcer effect, possibly through maintenance of mucin content and reduction of inflammation and oxidative stress".
Other polyphenol compound L-Theanine, isolated from green tea on NSAID (indomethacin)-induced maximum ulceration in the stomach on the third day at dose of 18 mg/kg inhibited the expression of the overproduction of reactive oxygen species (ROS) in the induction of lipid peroxidation, oxidation and protein carbonylation which is considered one of the most harmful irreversible oxidative protein that cause damage to the stomach.
The application also reduced the expression of type 1 T helper (Th1) cells in the production of inflammatory cytokines, interferon-gamma, interleukin (IL)-2, and tumor necrosis factor (TNF)-beta, in the facilitated immune response in exhibiting inflammation in the acute stomach damage infection.
Additionally, L-Theanine also increased the levels of total thiol in the stomach tissue, mucin content in the gastric juice. The enhanced antioxidant levels not only improve digestion but also protect the stomach against damage by foreign substances.
Moreover, at a higher dose of 40 mg/kg b.w. At 10 mg/kg b.w., Dr. Chatterjee S, the lead author said, "L-theanine significantly alleviated the adverse oxidative effect of indomethacin through enhanced synthesis of PGE2 by modulation of cyclooxygenase-1 and 2 [COX-1 and COX-2] expression, Th1/Th2 cytokine balance, and restoration of cellular antioxidant status at the gastric ulcer margin".
Taken together, been tea with abundant bioactive polyphenols may be considered functional food for the treatment of gastric ulcers without causing any adverse effects.
However, high doses and long-term applications of green tea supplements were associated with acute liver toxicity.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Healing mechanisms of the hydroalcoholic extract and ethyl acetate fraction of green tea(Camellia sinensis (L.) Kuntze) on chronic gastric ulcers by Borato DG1, Scolaro CT2, Maria-Ferreira D1, da Silva LM1, de Souza LM2, Iacomini M2, Werner MF1, Baggio CH3. (PubMed)
(2) L-Theanine healed NSAID-induced gastric ulcer by modulating pro/antioxidant balance in gastric ulcer margin by Chatterjee S1, Chatterjee A, Roy S, Bera B, Bandyopadhyay SK. (PubMed)
Gastric ulcers are sores that develop in the lining of the stomach as a result of a bacterial infection or by overproduction of stomach acid. In other words, gastric ulcer is a condition characterized by open sores developed in the stomach, affecting the function of the stomach.
There are a set of factors that cause a gastric ulcer, including the infection of Helicobacter pylori (H. pylori), frequent use of anti-inflammatory medicine, aging, smoking and excessive alcohol drinking
Some researchers suggested that people who have radiation therapy for stomach cancer are also a higher risk of gastric ulcer development.
According to the study "Are genetic influences on peptic ulcer dependent or independent of genetic influences for Helicobacter pylori infection?" by the Veterans Affairs Medical Center and Baylor College of Medicine. "Genetic influences are of moderate importance for liability to peptic ulcer disease. Genetic influences for peptic ulcer are independent of genetic influences important for acquiring H. pylori infection".
If you are experiencing the symptoms of dull pain in the stomach. weight loss. refuse to eat because of pain. persistent gastrointestinal discomforts, acid reflux, and heartburn, you may have a gastric ulcer. Please make sure that you check with your doctor to rule out the possibility.
Green tea, a precious drink processes a numbers of health benefits known to almost everyone in Asia and the Western world.
In the testing of healing of the hydroalcoholic extract including ethyl acetate fraction, (GEAc) and epigallocatechin gallate (EGCG) from green tea (GEt) in the risk of gastric ulcer induced by application of 80 % acetic acid on serosal mucosa of rats, researchers showed that application of the extract after 7 days inhibited ulcer area by exhibiting the antioxidant activity in reducing the free radical overexpression.
Furthermore, application of the hydroalcoholic extract also inhibited the oxidative stress that cause gastric damage by injection of acetic acid by enhancing the production of antioxidant enzyme GSH, superoxide dismutase (SOD) and Glutathione-S-transferase (GST) enzymes and ameliorating the production of lipid hydroperoxides (LOOH), a free radical in precipitated ulcer development by withdrawing electrons from the lipids in cell membranes.
Additional analysis also suggested that rats fed with green tea (GEt) improved the capacity of mucin content in gastric juice which has been found at reduced levels in rats with an ulcer after infecting of acetic acid.
Interestingly, injection of green tea (GEt) also decreased inflammatory infiltration of Myeloperoxidase (MPO) and N-acetylglucosaminidase (NAG) which has been used as biomarkers in the measurement of severity in some diseases including gastric ulcer.
Importantly, the application did not alter gastric acid secretion and induced acute toxicity.
Dr. Borato DG, the lead authors, after taking into account con-founders said, "GEt had a pronounced antiulcer effect, possibly through maintenance of mucin content and reduction of inflammation and oxidative stress".
Other polyphenol compound L-Theanine, isolated from green tea on NSAID (indomethacin)-induced maximum ulceration in the stomach on the third day at dose of 18 mg/kg inhibited the expression of the overproduction of reactive oxygen species (ROS) in the induction of lipid peroxidation, oxidation and protein carbonylation which is considered one of the most harmful irreversible oxidative protein that cause damage to the stomach.
The application also reduced the expression of type 1 T helper (Th1) cells in the production of inflammatory cytokines, interferon-gamma, interleukin (IL)-2, and tumor necrosis factor (TNF)-beta, in the facilitated immune response in exhibiting inflammation in the acute stomach damage infection.
Additionally, L-Theanine also increased the levels of total thiol in the stomach tissue, mucin content in the gastric juice. The enhanced antioxidant levels not only improve digestion but also protect the stomach against damage by foreign substances.
Moreover, at a higher dose of 40 mg/kg b.w. At 10 mg/kg b.w., Dr. Chatterjee S, the lead author said, "L-theanine significantly alleviated the adverse oxidative effect of indomethacin through enhanced synthesis of PGE2 by modulation of cyclooxygenase-1 and 2 [COX-1 and COX-2] expression, Th1/Th2 cytokine balance, and restoration of cellular antioxidant status at the gastric ulcer margin".
Taken together, been tea with abundant bioactive polyphenols may be considered functional food for the treatment of gastric ulcers without causing any adverse effects.
However, high doses and long-term applications of green tea supplements were associated with acute liver toxicity.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Healing mechanisms of the hydroalcoholic extract and ethyl acetate fraction of green tea(Camellia sinensis (L.) Kuntze) on chronic gastric ulcers by Borato DG1, Scolaro CT2, Maria-Ferreira D1, da Silva LM1, de Souza LM2, Iacomini M2, Werner MF1, Baggio CH3. (PubMed)
(2) L-Theanine healed NSAID-induced gastric ulcer by modulating pro/antioxidant balance in gastric ulcer margin by Chatterjee S1, Chatterjee A, Roy S, Bera B, Bandyopadhyay SK. (PubMed)
Phytochemical Betaxanthins, the Best Antioxidants
Antioxidants that inhibit oxidation are stable molecules produced by the host or from the dietary sources.
Free radicals are highly reactive and unstable atoms with a single electron on the outermost ring. To become stable, free radicals intercept or donate an electron from stable atoms, leading to a chain reaction that can not be stopped until all electrons on the outermost ring are paired or inhibited by antioxidants.
Oxidative stress is a result of overexpression of free radicals compared to low levels of antioxidants in the body. Over time, oxidative stress induces protein, lipid, and cellular damage, leading to cells injury and death that facilitate the onset of chronic diseases, including CVD and cancer.
However, free radicals at a moderate level are necessary for the body function, including maintaining the blood vessels in the regulation of relaxation and constriction.
Some diseases associated with free radicals are
* Cancers
Free radical-induced oxidative stress causes alteration of DNA, leading to the possible development of cancer.
* Atherosclerosis
Atherosclerosis developing is associated with the oxidation of low-density lipoprotein molecules (LDL) or bad cholesterol, that leads to damage to the arterial wall.
* Ischemia
Researchers found that free radicals generated during oxidated stress through a series of interacting pathways in cardiac myocytes and endothelial cells can lead to the increased post-ischemic heart and post-ischemic injury.
* Diabetes mellitus
Diabetes mellitus reduced the ability of the body to regulate peroxide and transition metal metabolism that result in the establishment of the disease-induced longer-term complications such as atherosclerosis, kidney, and nerve damage as well as blindness.
* Lung disease
The implication of oxygen and air pollutants induced free radical activity have become obvious as our lung is the only organs to take in oxygen from the atmosphere.
Betaxanthins are Phytochemicals in the class of red and yellow indole-derived pigments, belongings to the group of Betalains, found abundantly in beets, Sicilian prickly pear, etc.
On finding a natural compound for the treatment of diseases associated with oxidative stress, researchers examined the betaxanthin's antioxidant capacity in Stenocereus pruinosus over a range of pH.
Based on the chemical analysis, the stability of betaxanthins was found to represent 89% of total betalains in yellow pitayas.
More precisely, the Maximum stability betaxanthins were observed at pH6.6, and the addition of ascorbic acid increased the half-life 1.8 times.
Additionally, betaxanthins were found to be more stable in gummies than in beverages observed by the increase of pigment retention increased in products that were stored in the dark or at low temperatures.
These results strongly suggested that betaxanthins exerted significant antioxidant activity.
Taken altogether, betaxanthins may be considered a natural antixodants against the onset of oxidative stress, pending to the confirmation of the larger sample size and multicenter human study.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You. How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Betaxanthins and antioxidant capacity in Stenocereus pruinosus: Stability and use in food by Rodríguez-Sánchez JA1, Cruz Y Victoria MT2, Barragán-Huerta BE. (PubMed)
Free radicals are highly reactive and unstable atoms with a single electron on the outermost ring. To become stable, free radicals intercept or donate an electron from stable atoms, leading to a chain reaction that can not be stopped until all electrons on the outermost ring are paired or inhibited by antioxidants.
Oxidative stress is a result of overexpression of free radicals compared to low levels of antioxidants in the body. Over time, oxidative stress induces protein, lipid, and cellular damage, leading to cells injury and death that facilitate the onset of chronic diseases, including CVD and cancer.
However, free radicals at a moderate level are necessary for the body function, including maintaining the blood vessels in the regulation of relaxation and constriction.
Some diseases associated with free radicals are
* Cancers
Free radical-induced oxidative stress causes alteration of DNA, leading to the possible development of cancer.
* Atherosclerosis
Atherosclerosis developing is associated with the oxidation of low-density lipoprotein molecules (LDL) or bad cholesterol, that leads to damage to the arterial wall.
* Ischemia
Researchers found that free radicals generated during oxidated stress through a series of interacting pathways in cardiac myocytes and endothelial cells can lead to the increased post-ischemic heart and post-ischemic injury.
* Diabetes mellitus
Diabetes mellitus reduced the ability of the body to regulate peroxide and transition metal metabolism that result in the establishment of the disease-induced longer-term complications such as atherosclerosis, kidney, and nerve damage as well as blindness.
* Lung disease
The implication of oxygen and air pollutants induced free radical activity have become obvious as our lung is the only organs to take in oxygen from the atmosphere.
Betaxanthins are Phytochemicals in the class of red and yellow indole-derived pigments, belongings to the group of Betalains, found abundantly in beets, Sicilian prickly pear, etc.
On finding a natural compound for the treatment of diseases associated with oxidative stress, researchers examined the betaxanthin's antioxidant capacity in Stenocereus pruinosus over a range of pH.
Based on the chemical analysis, the stability of betaxanthins was found to represent 89% of total betalains in yellow pitayas.
More precisely, the Maximum stability betaxanthins were observed at pH6.6, and the addition of ascorbic acid increased the half-life 1.8 times.
Additionally, betaxanthins were found to be more stable in gummies than in beverages observed by the increase of pigment retention increased in products that were stored in the dark or at low temperatures.
These results strongly suggested that betaxanthins exerted significant antioxidant activity.
Taken altogether, betaxanthins may be considered a natural antixodants against the onset of oxidative stress, pending to the confirmation of the larger sample size and multicenter human study.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You. How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Betaxanthins and antioxidant capacity in Stenocereus pruinosus: Stability and use in food by Rodríguez-Sánchez JA1, Cruz Y Victoria MT2, Barragán-Huerta BE. (PubMed)
Herbal Alfalfa, A Potent and Natural Dietary Antioxidants
Herbal alfalfa may have a profound and positive effect on enhancing the expression of antioxidants in the body, some scientists suggested.
Antioxidants are stable molecules that inhibit oxidation induced by free radicals.
A free radical is a highly reactive atom with a single electron in the outer ring.
Free radicals produced in our body is a natural process derived either from essential metabolism through the processes of food intake or from external sources through directly contacting the skin or the air we breathe including exposure to X-rays, ozone, cigarette smoking, air pollutants, and industrial chemicals.
Some foods are antioxidants producers such as fruits and vegetables and whole-grain, while others such as processed meats, alcohol are radicals producers. Particularly, fats and oils can easily be oxidized if they are cooked in high heat.
In order to counter the overexpression of free radicals which add to the body's burden, our body produces enzymes antioxidants and metal carrier proteins to neutralize them before they can cause damage.
Depending on the degrees of free radical invasion, antioxidant enzymes can be categorized into first, second, third and even fourth line of defense.
Dr. O.M, in the examine the antioxidant defense wrote, "The role and effectiveness of the first-line defense antioxidants which basically include superoxide dismutase (SOD), catalase (CAT) and glutathione peroxidase (GPX) is important and indispensable in the entire defense strategy of antioxidants, especially in reference to superoxide anion radical (*O2) which is perpetually generated in normal body metabolism, particularly through the mitochondrial energy production pathway (MEPP)".
The statement clearly suggested that in healthy individual antioxidant enzymes synthesized form our body is good enough to protect the body from bombardments of free radicals.
However, for people with a weakened immune system, chronic illness, dietary sources of antioxidants may be needed.
Oxidative stress is a result of the imbalance of free radicals and antioxidants in the body. The syndrome is either caused by overexpression of free radicals or depressed levels of antioxidants or both.
Oxidative stress has been found to induce widespread damage due to a set of a chain reaction auto-catalytically by free radicals that attacks the lipid bilayers of the cell walls, induces lipid, protein damage and alternation of cell DNA, leading to the onset of chronic diseases, including cancers.
Alfalfa is a flowering plant in the genus Medicago, belongings to the family Fabaceae.
The herb has been cultivated all over the world as hay for cattle feeding. The leaves, sprouts, and seeds to make medicine has been used in traditional medicine over thousands of year for the treatment of high cholesterol, asthma, osteoarthritis, rheumatoid arthritis, diabetes, enhance digestive system, bleeding disorder, kidney, and urinary tract infection, etc.
North America aboriginal has used Alfalfa seed as food, such as making bread and mush.
In reaffirming the herbal alfalfa antioxidant activity especially scavenging activity for hydroxyl radical and DPPH radical, researchers launched a study to determine whether a lyophilized aqueous extract of alfalfa or Medicago sativa L. could exert antioxidant activity against carbon tetrachloride-induced oxidative stress and liver injury in rats.
Before injecting the lyophilized aqueous extract of alfalfa, rats treated by CCl (4) showed a significant increase of serum of oxidative stress markers observed by the levels of transaminase, ALP, bilirubin, lipid profile. and liver MDA accompanied by the decline of antioxidant status in liver non-protein sulfhydryl (NP-SH); and total protein (TP) contents.
Pretreatment with alfalfa and silymarin for three weeks prior to the administration of CCl (4) significantly prevented the increase of oxidative markers by reducing the oxidative stress indicated by elevated NP-SH and TP concentration of the antioxidant liver enzyme.
Futhermore, the incidence of liver lesion induced by the injection of CCL(4) also reduced by the pretreatment of alfalfa extract.
The application of alfalfa extracts also exerted a potent scavenging activity against hydroxyl radical and DPPH radical.
These results indicated that alfalfa may be considered a novel natural antioxidant. Dr.Al-Dosari MS wrote in the final report, " alfalfa extract possesses hepatoprotective and antioxidative stress properties possibly through its antioxidant phytochemical constituents and substantiates its use in various liver disorders as a hepatoprotector".
Additionally, researchers at the University of Life Sciences in Lublin, in the testing antioxidant effect of a dietary protein-xanthophylls (PX) concentrate of alfalfa on raw meat launched an evaluation by adding the concentration in turkey diet.
The study included 120 turkeys assigned randomly assigned to 3 groups (group I-control group; group II--with 1.5% supplementation of the protein-xanthophylls (PX) concentrate; group III--with 3% supplementation of the protein-xanthophylls (PX) concentrate).
The addition of protein-xanthophylls (PX) concentration of alfalfa to a turkey diet protects the deterioration of breast and thigh meat quality.
Also, by examining the changes in color, oxymyoglobin content, TBARS, and oxidation-reduction potential values, researchers said " the inclusion of the concentration to turkey diets acts as an antioxidant in the raw meat.
Taken altogether, alfalfa may be considered a natural antioxidant which improves the antioxidant profile in the body against the overexpression of free radicals in the initiation of oxidative stress.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
References
(1). In vitro and in vivo antioxidant activity of alfalfa (Medicago sativa L.) on carbon tetrachloride intoxicated rats. by Al-Dosari MS (PubMed).
(2). Effect of protein-xanthophylls (PX) concentrate of alfalfa supplementation on physico-chemical properties of turkey breast and thigh muscles during ageing. by Karwowska M, Stadnik J, Dolatowski ZJ, Grela ER. (PubMed)
(3) First line defense antioxidants-superoxide dismutase (SOD), catalase (CAT) and glutathione peroxidase (GPX): Their fundamental role in the entire antioxidant defense grid by O.M.Ighodaroab, O.A.Akinloyeb. (Science Direct)
Antioxidants are stable molecules that inhibit oxidation induced by free radicals.
A free radical is a highly reactive atom with a single electron in the outer ring.
Free radicals produced in our body is a natural process derived either from essential metabolism through the processes of food intake or from external sources through directly contacting the skin or the air we breathe including exposure to X-rays, ozone, cigarette smoking, air pollutants, and industrial chemicals.
Some foods are antioxidants producers such as fruits and vegetables and whole-grain, while others such as processed meats, alcohol are radicals producers. Particularly, fats and oils can easily be oxidized if they are cooked in high heat.
In order to counter the overexpression of free radicals which add to the body's burden, our body produces enzymes antioxidants and metal carrier proteins to neutralize them before they can cause damage.
Depending on the degrees of free radical invasion, antioxidant enzymes can be categorized into first, second, third and even fourth line of defense.
Dr. O.M, in the examine the antioxidant defense wrote, "The role and effectiveness of the first-line defense antioxidants which basically include superoxide dismutase (SOD), catalase (CAT) and glutathione peroxidase (GPX) is important and indispensable in the entire defense strategy of antioxidants, especially in reference to superoxide anion radical (*O2) which is perpetually generated in normal body metabolism, particularly through the mitochondrial energy production pathway (MEPP)".
The statement clearly suggested that in healthy individual antioxidant enzymes synthesized form our body is good enough to protect the body from bombardments of free radicals.
However, for people with a weakened immune system, chronic illness, dietary sources of antioxidants may be needed.
Oxidative stress is a result of the imbalance of free radicals and antioxidants in the body. The syndrome is either caused by overexpression of free radicals or depressed levels of antioxidants or both.
Oxidative stress has been found to induce widespread damage due to a set of a chain reaction auto-catalytically by free radicals that attacks the lipid bilayers of the cell walls, induces lipid, protein damage and alternation of cell DNA, leading to the onset of chronic diseases, including cancers.
Alfalfa is a flowering plant in the genus Medicago, belongings to the family Fabaceae.
The herb has been cultivated all over the world as hay for cattle feeding. The leaves, sprouts, and seeds to make medicine has been used in traditional medicine over thousands of year for the treatment of high cholesterol, asthma, osteoarthritis, rheumatoid arthritis, diabetes, enhance digestive system, bleeding disorder, kidney, and urinary tract infection, etc.
North America aboriginal has used Alfalfa seed as food, such as making bread and mush.
In reaffirming the herbal alfalfa antioxidant activity especially scavenging activity for hydroxyl radical and DPPH radical, researchers launched a study to determine whether a lyophilized aqueous extract of alfalfa or Medicago sativa L. could exert antioxidant activity against carbon tetrachloride-induced oxidative stress and liver injury in rats.
Before injecting the lyophilized aqueous extract of alfalfa, rats treated by CCl (4) showed a significant increase of serum of oxidative stress markers observed by the levels of transaminase, ALP, bilirubin, lipid profile. and liver MDA accompanied by the decline of antioxidant status in liver non-protein sulfhydryl (NP-SH); and total protein (TP) contents.
Pretreatment with alfalfa and silymarin for three weeks prior to the administration of CCl (4) significantly prevented the increase of oxidative markers by reducing the oxidative stress indicated by elevated NP-SH and TP concentration of the antioxidant liver enzyme.
Futhermore, the incidence of liver lesion induced by the injection of CCL(4) also reduced by the pretreatment of alfalfa extract.
The application of alfalfa extracts also exerted a potent scavenging activity against hydroxyl radical and DPPH radical.
These results indicated that alfalfa may be considered a novel natural antioxidant. Dr.Al-Dosari MS wrote in the final report, " alfalfa extract possesses hepatoprotective and antioxidative stress properties possibly through its antioxidant phytochemical constituents and substantiates its use in various liver disorders as a hepatoprotector".
Additionally, researchers at the University of Life Sciences in Lublin, in the testing antioxidant effect of a dietary protein-xanthophylls (PX) concentrate of alfalfa on raw meat launched an evaluation by adding the concentration in turkey diet.
The study included 120 turkeys assigned randomly assigned to 3 groups (group I-control group; group II--with 1.5% supplementation of the protein-xanthophylls (PX) concentrate; group III--with 3% supplementation of the protein-xanthophylls (PX) concentrate).
The addition of protein-xanthophylls (PX) concentration of alfalfa to a turkey diet protects the deterioration of breast and thigh meat quality.
Also, by examining the changes in color, oxymyoglobin content, TBARS, and oxidation-reduction potential values, researchers said " the inclusion of the concentration to turkey diets acts as an antioxidant in the raw meat.
Taken altogether, alfalfa may be considered a natural antioxidant which improves the antioxidant profile in the body against the overexpression of free radicals in the initiation of oxidative stress.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
References
(1). In vitro and in vivo antioxidant activity of alfalfa (Medicago sativa L.) on carbon tetrachloride intoxicated rats. by Al-Dosari MS (PubMed).
(2). Effect of protein-xanthophylls (PX) concentrate of alfalfa supplementation on physico-chemical properties of turkey breast and thigh muscles during ageing. by Karwowska M, Stadnik J, Dolatowski ZJ, Grela ER. (PubMed)
(3) First line defense antioxidants-superoxide dismutase (SOD), catalase (CAT) and glutathione peroxidase (GPX): Their fundamental role in the entire antioxidant defense grid by O.M.Ighodaroab, O.A.Akinloyeb. (Science Direct)
Herbal Aloe Vera Gobbles Up Cancer Cells in Vivo and Vitro
Aloe Vera may be the next target for the pharmaceutical companies to extract a single ingredient for the treatment of cancers, some scientists suggested.
Cancers are a class of medical diseases associated with cell growth irregularly and disorderly in some specific tissue and organs.
Most cancer starts at the cell on the surface of the inner lining of the organ's tissue. At the later stage, cancer cells can be found in the deeper of layers of the infected organ.
In the advanced stage, malignant cells can travel a distance away from the original site to infect other healthy tissue and organ through the circulation of fluids and blood.
The causes of cancer are the results of the alternation of healthy cell DNA. Researchers do not why the healthy cell' DNA is alternated.
Normally, healthy cells undergo a certain number of cell cycle divisions than die. In a cancerous cell, cell division undergoes indefinitely.
According to the statistic, approximately 38.4% of men and women will be diagnosed with cancer at some point during their lifetimes.
The genetic mutation of the cancer cell may be associated with certain risk factors. Epidemiological studies suggested that long-term exposure to carcinogens, the increased in age, gender, inherited genetic defects and skin type can increase the risk the cancer onset.
Most common and general symptoms of cancer are unintended weight loss, lump, fatigue, loss of appetite and persistent localized symptoms and localized pain in the later stage.
If you experience some of the above symptoms, please check with your doctor right the way to rule out the possibility of cancer.
Out of numbers of the risk factor, the genetic preposition has been under intensive studied by many scientists.
Dr. Eric T, the lead author on the study of genetic implication on the cancer risk said, "Genetic testing for inherited cancer risk is now widely used to target individuals for screening and prevention" and
"Overall, 17,340 PVs were identified in 17,000 (6.7%) of the tested individuals. The pathogenic variants (PV) positive rate was 9.8% among individuals with a personal cancer history, compared to 4.7% in unaffected individuals. PVs were most common in BRCA1/2 (42.2%), other breast cancer (BR) genes (32.9%), and the LS genes (13.2%)".
These results clearly stated that people who carry certain mutated genes are at the substantial risk of cancer onset, compared to those who do not.
Aloe Vera is species of succulent plant in the genus Aloe, belonging to the Family Xanthorrhoeaceae, native to Sudan. It has become very popular for commercial cultivation due to its health benefits.
Aloe vera has been used in herbal medicine in treating many kinds of diseases, including wound, burn healing, minor skin infections, sebaceous cysts, diabetes, and elevated cholesterol, etc.
It is also one of many popular herbs studied in scientific ways with some conflicting results.
The ten main areas of chemical constituents of Aloe vera are amino acids, anthraquinones, enzymes, minerals, vitamins, lignins, monosaccharide, polysaccharides, salicylic acid, saponins, and sterols.
They all work together in a synergistic way to create healing and health-giving benefits, according to Gertrude Baldwin in the article of THE BENEFITS OF THE USE OF ALOE VERA IN HERBAL PREPARATIONS.
In the finding, a natural ingredient for the treatment of breast cancer without inducing side effects, researchers at the National Chung Hsing University conducted a study to compare the efficacy of Emodin and Aloe-Emodin, the major bioactive compound found in herbal Aloe Vera.
By analyzing the estrogenic activity as phytoestrogens on the estrogen receptor α (ER α ) activation and breast cancer cell growth, application of both emodin and aloe-emodin are capable of inhibiting breast cancer cell proliferation by reducing the ER α protein levels which has been found in high levels in patient with breast cancer thereby suppressing ER α transcriptional (mRNA) activation..
High expression of ERα mRNA is found associated with patients with breast cancer.
Breast cancer treatment with aloe-emodin also decreases the expression of the levels of ERα associated with the protein that stimulates the division of breast cancer cells by increasing the cancer cell's degradation.
The efficacy of aloe-emodin inhibited breast cancer proliferation and induced apoptosis is attributed to breaking down the cytoplasm of ER α protein in the breast cancer cells.
The results suggested that aloe-emodin suppressed breast cell proliferation emodin by targeting ER α protein expression through distinct mechanisms.
Further demonstration of the effect of aloe-emodin on the risk of cancer, researchers examined whether aloe-emodin exerts a similar effect on the growth of human cervical cancer cells, HeLa.
Human cervical cancer cells, HeLa used in the experiment were treated by different doses of aloe-emodin for 1-5 days,.
Measured by 3-(4, 5-dimethylthiazol-2-yl)-2, 5-diphenyl tetrazolium bromide assay, aloe-emodin displays significant effects in the inhibition of the growth of HeLa cells in a dose-dependent manner at concentrations ranging between 2.5 and 40 micromol/L.
Aloe-emodin induces HeLa cells death by disrupting the cell cycle division at the G2/M phase, according to the flow cytometric analysis.
The effects of aloe-emodin inhibited the human by increasing the expression of proteins associated with cell death programming and reducing the expression of proteins associated with cancer prefiltration and survival.
Most importantly, after taking into account co and confounders, researchers discovered, aloe-emodin also activates the enzyme associated with the break down the protein of ER α and deactivates the enzyme associated with cell proliferation
Taken altogether, Aloe vera with the abundant aloe-emodin may be considered a functional food for the prevention and an adjunct therapy combined with the primary medicine for treatment of cancer without inducing adverse effects.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
References
(1) ALOE VERA by Gertrude Baldwin, http://www.herballegacy.com/Baldwin_Chemical.html
(2) Emodin and Aloe-Emodin Suppress Breast Cancer Cell Proliferation through ER α Inhibition.
Huang PH, Huang CY, Chen MC, Lee YT, Yue CH, Wang HY, Lin H.(PubMed)
(3) Growth inhibitory effects of gastric cancer cells with an increase in S phase and alkaline phosphatase activity repression by aloe-emodin. by Guo J, Xiao B, Zhang S, Liu D, Liao Y, Sun Q.(PubMed)
(4) Anticancer effect of aloe-emodin on cervical cancer cells involves G2/M arrest and induction of differentiation. by Guo JM, Xiao BX, Liu Q, Zhang S, Liu DH, Gong ZH.(PubMed)
(5) Clinical testing with a panel of 25 genes associated with increased cancer risk results in a significant increase in clinically significant findings across a broad range of cancer histories by (Research Gate)
Cancers are a class of medical diseases associated with cell growth irregularly and disorderly in some specific tissue and organs.
Most cancer starts at the cell on the surface of the inner lining of the organ's tissue. At the later stage, cancer cells can be found in the deeper of layers of the infected organ.
In the advanced stage, malignant cells can travel a distance away from the original site to infect other healthy tissue and organ through the circulation of fluids and blood.
The causes of cancer are the results of the alternation of healthy cell DNA. Researchers do not why the healthy cell' DNA is alternated.
Normally, healthy cells undergo a certain number of cell cycle divisions than die. In a cancerous cell, cell division undergoes indefinitely.
According to the statistic, approximately 38.4% of men and women will be diagnosed with cancer at some point during their lifetimes.
The genetic mutation of the cancer cell may be associated with certain risk factors. Epidemiological studies suggested that long-term exposure to carcinogens, the increased in age, gender, inherited genetic defects and skin type can increase the risk the cancer onset.
Most common and general symptoms of cancer are unintended weight loss, lump, fatigue, loss of appetite and persistent localized symptoms and localized pain in the later stage.
If you experience some of the above symptoms, please check with your doctor right the way to rule out the possibility of cancer.
Out of numbers of the risk factor, the genetic preposition has been under intensive studied by many scientists.
Dr. Eric T, the lead author on the study of genetic implication on the cancer risk said, "Genetic testing for inherited cancer risk is now widely used to target individuals for screening and prevention" and
"Overall, 17,340 PVs were identified in 17,000 (6.7%) of the tested individuals. The pathogenic variants (PV) positive rate was 9.8% among individuals with a personal cancer history, compared to 4.7% in unaffected individuals. PVs were most common in BRCA1/2 (42.2%), other breast cancer (BR) genes (32.9%), and the LS genes (13.2%)".
These results clearly stated that people who carry certain mutated genes are at the substantial risk of cancer onset, compared to those who do not.
Aloe Vera is species of succulent plant in the genus Aloe, belonging to the Family Xanthorrhoeaceae, native to Sudan. It has become very popular for commercial cultivation due to its health benefits.
Aloe vera has been used in herbal medicine in treating many kinds of diseases, including wound, burn healing, minor skin infections, sebaceous cysts, diabetes, and elevated cholesterol, etc.
It is also one of many popular herbs studied in scientific ways with some conflicting results.
The ten main areas of chemical constituents of Aloe vera are amino acids, anthraquinones, enzymes, minerals, vitamins, lignins, monosaccharide, polysaccharides, salicylic acid, saponins, and sterols.
They all work together in a synergistic way to create healing and health-giving benefits, according to Gertrude Baldwin in the article of THE BENEFITS OF THE USE OF ALOE VERA IN HERBAL PREPARATIONS.
In the finding, a natural ingredient for the treatment of breast cancer without inducing side effects, researchers at the National Chung Hsing University conducted a study to compare the efficacy of Emodin and Aloe-Emodin, the major bioactive compound found in herbal Aloe Vera.
By analyzing the estrogenic activity as phytoestrogens on the estrogen receptor α (ER α ) activation and breast cancer cell growth, application of both emodin and aloe-emodin are capable of inhibiting breast cancer cell proliferation by reducing the ER α protein levels which has been found in high levels in patient with breast cancer thereby suppressing ER α transcriptional (mRNA) activation..
High expression of ERα mRNA is found associated with patients with breast cancer.
Breast cancer treatment with aloe-emodin also decreases the expression of the levels of ERα associated with the protein that stimulates the division of breast cancer cells by increasing the cancer cell's degradation.
The efficacy of aloe-emodin inhibited breast cancer proliferation and induced apoptosis is attributed to breaking down the cytoplasm of ER α protein in the breast cancer cells.
The results suggested that aloe-emodin suppressed breast cell proliferation emodin by targeting ER α protein expression through distinct mechanisms.
Further demonstration of the effect of aloe-emodin on the risk of cancer, researchers examined whether aloe-emodin exerts a similar effect on the growth of human cervical cancer cells, HeLa.
Human cervical cancer cells, HeLa used in the experiment were treated by different doses of aloe-emodin for 1-5 days,.
Measured by 3-(4, 5-dimethylthiazol-2-yl)-2, 5-diphenyl tetrazolium bromide assay, aloe-emodin displays significant effects in the inhibition of the growth of HeLa cells in a dose-dependent manner at concentrations ranging between 2.5 and 40 micromol/L.
Aloe-emodin induces HeLa cells death by disrupting the cell cycle division at the G2/M phase, according to the flow cytometric analysis.
The effects of aloe-emodin inhibited the human by increasing the expression of proteins associated with cell death programming and reducing the expression of proteins associated with cancer prefiltration and survival.
Most importantly, after taking into account co and confounders, researchers discovered, aloe-emodin also activates the enzyme associated with the break down the protein of ER α and deactivates the enzyme associated with cell proliferation
Taken altogether, Aloe vera with the abundant aloe-emodin may be considered a functional food for the prevention and an adjunct therapy combined with the primary medicine for treatment of cancer without inducing adverse effects.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
References
(1) ALOE VERA by Gertrude Baldwin, http://www.herballegacy.com/Baldwin_Chemical.html
(2) Emodin and Aloe-Emodin Suppress Breast Cancer Cell Proliferation through ER α Inhibition.
Huang PH, Huang CY, Chen MC, Lee YT, Yue CH, Wang HY, Lin H.(PubMed)
(3) Growth inhibitory effects of gastric cancer cells with an increase in S phase and alkaline phosphatase activity repression by aloe-emodin. by Guo J, Xiao B, Zhang S, Liu D, Liao Y, Sun Q.(PubMed)
(4) Anticancer effect of aloe-emodin on cervical cancer cells involves G2/M arrest and induction of differentiation. by Guo JM, Xiao BX, Liu Q, Zhang S, Liu DH, Gong ZH.(PubMed)
(5) Clinical testing with a panel of 25 genes associated with increased cancer risk results in a significant increase in clinically significant findings across a broad range of cancer histories by (Research Gate)
Herbal Andrographis Modulates Immune Function To the Body Needs, Scientists Say
Herbal Andrographis paniculata may have a profound effect in enhancing the function of the immune system against disease development, some studies found.
The immune system is a set of cells that have a unique function to protect our body against antigens or infectious agents that comprises the body's defense system against diseases.
The immune system does a great job of keeping people healthy and preventing infections.
It is made of special cells (white blood cells), antibodies, tissues (bone marrow), and organs (the spleen) defend people against germs and microorganisms every day.
There are 3 types of immunity can be classified as the following
* The innate immunity is also known as natural immunity that every human born with.
* The adaptive immunity is the type of immunity that develops in the life of the individual.
* Passive immunity that borrows from the outside sources and can only last only a short period of time
There are 2 types of immune disorders
* Underactive immunity or immune deficiency. People with an underactive immune system are easy
to be infected or sick all the times
* Overactive immune system or autoimmune diseases. In this case, the immune system attacks the host tissue, causing autoimmune diseases such as rheumatoid arthritis (RA).
Andrographis paniculata is also known as Andrographis is a herbaceous plant, genus Andrographis, belonging to the family Acanthaceae, native to India and Sri Lanka.
The plant has been used in traditional Siddha and Ayurvedic in treating the common cold, flu, upper respiratory infections, infectious diseases, diarrhea, dysentery, cholera, pneumonia, swollen lymph nodes, leprosy, bronchitis, sore throats, tuberculosis, chickenpox, etc.
In finding a natural ingredient or formula for the treatment of immune dysfunction with no side effects, researchers at the Prin. K. M. Kundnani College of Pharmacy, launched an investigation to examine the immunomodulatory activity of HN-02, an extract containing a mixture of andrographolides.
The pure powder form of the mixture of andrographolides.was evaluated at 1.0, 1.5, and 2.5 mg/kg on different in vivo and in vitro experimental models.
Application of the mixture delayed-type hypersensitivity (DTH) caused by the injection of cyclophosphamide (CYP) in the mouse model.
Where cyclophosphamide (CP) is a medication used as chemotherapy and to suppress the immune system.
HN-02 treatment elevated the depressed hemagglutination antibody (HA) titer, the antibody and increased the number of plaque-forming cells (PFCs) in the spleen cells of mice caused by the injection of CYP.
HN-02 treatment stimulated phagocytosis in the immune system and increased levels of white blood cells in the tested mice.
These results strongly indicated HN-02 has the ability to enhance immune function by modulating the immune responses which were altered during antigen interaction and reversing the immunosuppression induced by CYP.
Furthermore, according to the Amala Cancer Research Centre in the examine the natural whole herb function in the modulation of immune responses against tumor cells, Andrographis paniculata extract (APE) and its isolated compound andrographolide (ANDLE) exert a clinically significant effect on cell-mediated immune responses in normal and tumor-bearing control animals.
Treatment with APE and ANDLE significantly enhanced natural killer cell activity in normal and tumor-bearing animals on the fifth day,
Antibody-dependent cellular cytotoxicity was also increased in APE as well as ANDLE on day 11-treated normal and tumor-bearing animals compared to untreated tumor-bearing control animals.
Moreover, treatment of APE and ANDLE significantly elevated the production of interleukin-2 which regulates the activities of white blood cells (leukocytes, often lymphocytes) and interferon-gamma which is critical for innate and adaptive immunity in normal and Ehrlich ascites carcinoma-bearing animals.
These results firmly indicated that herbal Andrographis may be considered functional food in the enhancement of the immune function against foreign stimuli and micro pathogens.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
References
(1) Evaluation of immunomodulatory activity of an extract of andrographolides from Andographis paniculata by Naik SR, Hule A.(PubMed)
(2) Modulation of natural killer cell activity, antibody-dependent cellular cytotoxicity, and antibody-dependent complement-mediated cytotoxicity by andrographolide in normal and Ehrlich ascites carcinoma-bearing mice by Sheeja K, Kuttan G.(PubMed)
(3) Activation of cytotoxic T lymphocyte responses and attenuation of tumor growth in vivo by Andrographis paniculata extract and andrographolide by Sheeja K, Kuttan G.(PubMed)
The immune system is a set of cells that have a unique function to protect our body against antigens or infectious agents that comprises the body's defense system against diseases.
The immune system does a great job of keeping people healthy and preventing infections.
It is made of special cells (white blood cells), antibodies, tissues (bone marrow), and organs (the spleen) defend people against germs and microorganisms every day.
There are 3 types of immunity can be classified as the following
* The innate immunity is also known as natural immunity that every human born with.
* The adaptive immunity is the type of immunity that develops in the life of the individual.
* Passive immunity that borrows from the outside sources and can only last only a short period of time
There are 2 types of immune disorders
* Underactive immunity or immune deficiency. People with an underactive immune system are easy
to be infected or sick all the times
* Overactive immune system or autoimmune diseases. In this case, the immune system attacks the host tissue, causing autoimmune diseases such as rheumatoid arthritis (RA).
Andrographis paniculata is also known as Andrographis is a herbaceous plant, genus Andrographis, belonging to the family Acanthaceae, native to India and Sri Lanka.
The plant has been used in traditional Siddha and Ayurvedic in treating the common cold, flu, upper respiratory infections, infectious diseases, diarrhea, dysentery, cholera, pneumonia, swollen lymph nodes, leprosy, bronchitis, sore throats, tuberculosis, chickenpox, etc.
In finding a natural ingredient or formula for the treatment of immune dysfunction with no side effects, researchers at the Prin. K. M. Kundnani College of Pharmacy, launched an investigation to examine the immunomodulatory activity of HN-02, an extract containing a mixture of andrographolides.
The pure powder form of the mixture of andrographolides.was evaluated at 1.0, 1.5, and 2.5 mg/kg on different in vivo and in vitro experimental models.
Application of the mixture delayed-type hypersensitivity (DTH) caused by the injection of cyclophosphamide (CYP) in the mouse model.
Where cyclophosphamide (CP) is a medication used as chemotherapy and to suppress the immune system.
HN-02 treatment elevated the depressed hemagglutination antibody (HA) titer, the antibody and increased the number of plaque-forming cells (PFCs) in the spleen cells of mice caused by the injection of CYP.
HN-02 treatment stimulated phagocytosis in the immune system and increased levels of white blood cells in the tested mice.
These results strongly indicated HN-02 has the ability to enhance immune function by modulating the immune responses which were altered during antigen interaction and reversing the immunosuppression induced by CYP.
Furthermore, according to the Amala Cancer Research Centre in the examine the natural whole herb function in the modulation of immune responses against tumor cells, Andrographis paniculata extract (APE) and its isolated compound andrographolide (ANDLE) exert a clinically significant effect on cell-mediated immune responses in normal and tumor-bearing control animals.
Treatment with APE and ANDLE significantly enhanced natural killer cell activity in normal and tumor-bearing animals on the fifth day,
Antibody-dependent cellular cytotoxicity was also increased in APE as well as ANDLE on day 11-treated normal and tumor-bearing animals compared to untreated tumor-bearing control animals.
Moreover, treatment of APE and ANDLE significantly elevated the production of interleukin-2 which regulates the activities of white blood cells (leukocytes, often lymphocytes) and interferon-gamma which is critical for innate and adaptive immunity in normal and Ehrlich ascites carcinoma-bearing animals.
These results firmly indicated that herbal Andrographis may be considered functional food in the enhancement of the immune function against foreign stimuli and micro pathogens.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
References
(1) Evaluation of immunomodulatory activity of an extract of andrographolides from Andographis paniculata by Naik SR, Hule A.(PubMed)
(2) Modulation of natural killer cell activity, antibody-dependent cellular cytotoxicity, and antibody-dependent complement-mediated cytotoxicity by andrographolide in normal and Ehrlich ascites carcinoma-bearing mice by Sheeja K, Kuttan G.(PubMed)
(3) Activation of cytotoxic T lymphocyte responses and attenuation of tumor growth in vivo by Andrographis paniculata extract and andrographolide by Sheeja K, Kuttan G.(PubMed)
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